#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P27692 uniprotkb:P32914 intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W intact:EBI-17928|uniprotkb:D6VUJ8|uniprotkb:Q0P6T7|uniprotkb:Q45U23|ensemblfungi:YGR063C psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:spt4_yeast(display_long)|uniprotkb:YGR063C(locus name)|uniprotkb:SPT4(gene name)|psi-mi:SPT4(display_short)|uniprotkb:Chromatin elongation factor SPT4(gene name synonym) psi-mi:"MI:0096"(pull down) Hartzog et al. (1998) pubmed:9450930 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1372141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692 sgd:S000003295|ensemblfungi:YGR063C(gene)|ensemblfungi:YGR063C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006397"(mRNA processing)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR009287(Transcription initiation Spt4)|interpro:IPR022800|interpro:IPR029040|interpro:IPR038510|rcsb pdb:2EXU|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-75955|refseq:NP_011577.3|dip:DIP-2078N|mint:P32914 - crc64:E4324DB6B1E4721A crc64:59C164193ABA883B figure legend:6A taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/19 2014/10/16 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 rogid:MC4Di+maCZ0kgCpzXXV0KP82pwU559292 intact-crc:7D28B728AC891803|rigid:1qKg72P33LZSk4536GsJDNBpUF4 false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P27692 uniprotkb:P23615 intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W intact:EBI-17947|uniprotkb:D6VUP7|ensemblfungi:YGR116W psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:spt6_yeast(display_long)|uniprotkb:CRE2(gene name synonym)|uniprotkb:SPT6(gene name)|psi-mi:SPT6(display_short)|uniprotkb:SSN20(gene name synonym)|uniprotkb:YGR116W(locus name)|uniprotkb:G6169(orf name)|uniprotkb:Chromatin elongation factor SPT6(gene name synonym) psi-mi:"MI:0096"(pull down) Hartzog et al. (1998) pubmed:9450930 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1372147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692 refseq:NP_011631.1|sgd:S000003348|ensemblfungi:YGR116W(gene)|ensemblfungi:YGR116W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000414"(regulation of histone H3-K36 methylation)|go:"GO:0000433"(carbon catabolite repression of transcription from RNA polymerase II promoter by glucose)|go:"GO:0001073"(transcription antitermination factor activity, DNA binding)|go:"GO:0001178"(regulation of transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0070827"(obsolete chromatin maintenance)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR000980(SH2 motif)|interpro:IPR006641(Resolvase, RNase H-like fold)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017072(Transcription elongation factor Spt6)|interpro:IPR023319|interpro:IPR023323|interpro:IPR028083|interpro:IPR028088|interpro:IPR028231|interpro:IPR032706|interpro:IPR035018|interpro:IPR035019|interpro:IPR035420|interpro:IPR036860|interpro:IPR037027|interpro:IPR042066|rcsb pdb:2L3T|rcsb pdb:3OAK|rcsb pdb:3PSF|rcsb pdb:3PSI|rcsb pdb:3PSJ|rcsb pdb:3PSK|rcsb pdb:5VKL|rcsb pdb:5VKO|reactome:R-SCE-674695|reactome:R-SCE-75955|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031564"(transcription antitermination)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034728"(nucleosome organization)|go:"GO:0035327"|go:"GO:0042393"(histone binding)|dip:DIP-2630N|mint:P23615 - crc64:E4324DB6B1E4721A crc64:0BE9922A59BD0483 figure legend:6A|comment:Only a weak association was detected. taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/19 2014/10/16 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 rogid:P9a7UCjdCVTSPp8jVc5NjDP4FZk559292 intact-crc:270E8F51BC70491B|rigid:ybPqzVbafKtnRicB++L45hZsHN4 false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P27692 uniprotkb:P32914 intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W intact:EBI-17928|uniprotkb:D6VUJ8|uniprotkb:Q0P6T7|uniprotkb:Q45U23|ensemblfungi:YGR063C psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:spt4_yeast(display_long)|uniprotkb:YGR063C(locus name)|uniprotkb:SPT4(gene name)|psi-mi:SPT4(display_short)|uniprotkb:Chromatin elongation factor SPT4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hartzog et al. (1998) pubmed:9450930 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1372158 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692 sgd:S000003295|ensemblfungi:YGR063C(gene)|ensemblfungi:YGR063C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006397"(mRNA processing)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR009287(Transcription initiation Spt4)|interpro:IPR022800|interpro:IPR029040|interpro:IPR038510|rcsb pdb:2EXU|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-75955|refseq:NP_011577.3|dip:DIP-2078N|mint:P32914 - crc64:E4324DB6B1E4721A crc64:59C164193ABA883B figure legend:6B taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/19 2014/10/16 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 rogid:MC4Di+maCZ0kgCpzXXV0KP82pwU559292 intact-crc:CDB8DBAC00D1BFC6|rigid:1qKg72P33LZSk4536GsJDNBpUF4 false - ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P32914 uniprotkb:P27692 intact:EBI-17928|uniprotkb:D6VUJ8|uniprotkb:Q0P6T7|uniprotkb:Q45U23|ensemblfungi:YGR063C intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W psi-mi:spt4_yeast(display_long)|uniprotkb:YGR063C(locus name)|uniprotkb:SPT4(gene name)|psi-mi:SPT4(display_short)|uniprotkb:Chromatin elongation factor SPT4(gene name synonym) psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hartzog et al. (1998) pubmed:9450930 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1372169 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003295|ensemblfungi:YGR063C(gene)|ensemblfungi:YGR063C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006397"(mRNA processing)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR009287(Transcription initiation Spt4)|interpro:IPR022800|interpro:IPR029040|interpro:IPR038510|rcsb pdb:2EXU|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-75955|refseq:NP_011577.3|dip:DIP-2078N|mint:P32914 refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692 - crc64:59C164193ABA883B crc64:E4324DB6B1E4721A figure legend:6C taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/19 2014/10/16 rogid:MC4Di+maCZ0kgCpzXXV0KP82pwU559292 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 intact-crc:A02E184E8EDA5683|rigid:1qKg72P33LZSk4536GsJDNBpUF4 false ha tag:?-? - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P32914 uniprotkb:P27692 intact:EBI-17928|uniprotkb:D6VUJ8|uniprotkb:Q0P6T7|uniprotkb:Q45U23|ensemblfungi:YGR063C intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W psi-mi:spt4_yeast(display_long)|uniprotkb:YGR063C(locus name)|uniprotkb:SPT4(gene name)|psi-mi:SPT4(display_short)|uniprotkb:Chromatin elongation factor SPT4(gene name synonym) psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hartzog et al. (1998) pubmed:9450930 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1372180 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003295|ensemblfungi:YGR063C(gene)|ensemblfungi:YGR063C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006397"(mRNA processing)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR009287(Transcription initiation Spt4)|interpro:IPR022800|interpro:IPR029040|interpro:IPR038510|rcsb pdb:2EXU|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-75955|refseq:NP_011577.3|dip:DIP-2078N|mint:P32914 refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692 - crc64:59C164193ABA883B crc64:E4324DB6B1E4721A figure legend:7 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/19 2014/10/16 rogid:MC4Di+maCZ0kgCpzXXV0KP82pwU559292 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 intact-crc:E0211E178056AFB5|rigid:1qKg72P33LZSk4536GsJDNBpUF4 false - flag tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P27692 uniprotkb:P04050 intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hartzog et al. (1998) pubmed:9450930 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1372188 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692 refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519 - crc64:E4324DB6B1E4721A crc64:A45C1360FF99F968 figure legend:7 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/19 2014/10/16 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 intact-crc:6A342ABA233ED9E8|rigid:1Nz6r+khjtjbfCWPk630e5jUdOk false flag tag:?-? - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)