#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q91XC0 uniprotkb:Q99684 intact:EBI-1565930|uniprotkb:P97472|ensembl:ENSMUSP00000056977 intact:EBI-949368|ensembl:ENSP00000294702|ensembl:ENSP00000359357|ensembl:ENSP00000399719|uniprotkb:Q8N564 psi-mi:ajuba_mouse(display_long)|uniprotkb:Ajuba(gene name)|psi-mi:Ajuba(display_short)|uniprotkb:Jub(gene name synonym) psi-mi:gfi1_human(display_long)|uniprotkb:Growth factor independent protein 1(gene name synonym)|uniprotkb:Zinc finger protein 163(gene name synonym)|uniprotkb:GFI1(gene name)|psi-mi:GFI1(display_short)|uniprotkb:ZNF163(gene name synonym) psi-mi:"MI:0018"(two hybrid) Ayyanathan et al. (2007) pubmed:17909014|imex:IM-18884 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1565925|imex:IM-18884-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034720.2|dip:DIP-38451N|ensembl:ENSMUSG00000022178(gene)|ensembl:ENSMUST00000054487(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000932"(P-body)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031328"(positive regulation of cellular biosynthetic process)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035313"(wound healing, spreading of epidermal cells)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001781(Zinc finger, LIM-type)|reactome:R-MMU-1234176|reactome:R-MMU-2565942 ensembl:ENSG00000162676(gene)|ensembl:ENST00000294702(transcript)|ensembl:ENST00000370332(transcript)|ensembl:ENST00000427103(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070105"(positive regulation of interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029840|interpro:IPR036236|reactome:R-HSA-9616222|refseq:NP_001120688.1|refseq:NP_005254.2|refseq:NP_001120687.1|dip:DIP-38452N|refseq:XP_011539547.1|refseq:XP_011539548.1|refseq:XP_005270806.1 - - - dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/12/07 2014/10/16 rogid:T6AUE1QVamCFkotRwItOeD2IyLY10090 rogid:BFND3tswCN4YNWrz8KZQeS0EZUw9606 intact-crc:70012BB507FA7336|rigid:JINKMMmrqyQF9VnKjmuAcKo9fAI false sufficient binding region:301-468 sufficient binding region:1-20 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99684 uniprotkb:Q9QXD8 intact:EBI-949368|ensembl:ENSP00000294702|ensembl:ENSP00000359357|ensembl:ENSP00000399719|uniprotkb:Q8N564 intact:EBI-1565949|uniprotkb:Q8C8G4|uniprotkb:Q9CW55|ensembl:ENSMUSP00000026269 psi-mi:gfi1_human(display_long)|uniprotkb:Growth factor independent protein 1(gene name synonym)|uniprotkb:Zinc finger protein 163(gene name synonym)|uniprotkb:GFI1(gene name)|psi-mi:GFI1(display_short)|uniprotkb:ZNF163(gene name synonym) psi-mi:limd1_mouse(display_long)|uniprotkb:Limd1(gene name)|psi-mi:Limd1(display_short) psi-mi:"MI:0018"(two hybrid) Ayyanathan et al. (2007) pubmed:17909014|imex:IM-18884 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1565957|imex:IM-18884-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162676(gene)|ensembl:ENST00000294702(transcript)|ensembl:ENST00000370332(transcript)|ensembl:ENST00000427103(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070105"(positive regulation of interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029840|interpro:IPR036236|reactome:R-HSA-9616222|refseq:NP_001120688.1|refseq:NP_005254.2|refseq:NP_001120687.1|dip:DIP-38452N|refseq:XP_011539547.1|refseq:XP_011539548.1|refseq:XP_005270806.1 refseq:NP_038888.2|dip:DIP-38453N|ensembl:ENSMUSG00000025239(gene)|ensembl:ENSMUST00000026269(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002076"(osteoblast development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016310"(phosphorylation)|go:"GO:0016442"(RISC complex)|go:"GO:0016477"(cell migration)|go:"GO:0033962"(P-body assembly)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR028734|mint:Q9QXD8|reactome:R-MMU-1234176 - - - dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/12/07 2014/10/16 rogid:BFND3tswCN4YNWrz8KZQeS0EZUw9606 rogid:l5HpR5SwbKwqzy6a/WUkwnKVkck10090 intact-crc:B14F01407E6448A5|rigid:qVkdyv8UI85Ei82QrckXHX9Naoc false sufficient binding region:1-20 sufficient binding region:398-593 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9QXD8 uniprotkb:Q99684 intact:EBI-1565949|uniprotkb:Q8C8G4|uniprotkb:Q9CW55|ensembl:ENSMUSP00000026269 intact:EBI-949368|ensembl:ENSP00000294702|ensembl:ENSP00000359357|ensembl:ENSP00000399719|uniprotkb:Q8N564 psi-mi:limd1_mouse(display_long)|uniprotkb:Limd1(gene name)|psi-mi:Limd1(display_short) psi-mi:gfi1_human(display_long)|uniprotkb:Growth factor independent protein 1(gene name synonym)|uniprotkb:Zinc finger protein 163(gene name synonym)|uniprotkb:GFI1(gene name)|psi-mi:GFI1(display_short)|uniprotkb:ZNF163(gene name synonym) psi-mi:"MI:0018"(two hybrid) Ayyanathan et al. (2007) pubmed:17909014|imex:IM-18884 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1565999|imex:IM-18884-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038888.2|dip:DIP-38453N|ensembl:ENSMUSG00000025239(gene)|ensembl:ENSMUST00000026269(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002076"(osteoblast development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016310"(phosphorylation)|go:"GO:0016442"(RISC complex)|go:"GO:0016477"(cell migration)|go:"GO:0033962"(P-body assembly)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR028734|mint:Q9QXD8|reactome:R-MMU-1234176 ensembl:ENSG00000162676(gene)|ensembl:ENST00000294702(transcript)|ensembl:ENST00000370332(transcript)|ensembl:ENST00000427103(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070105"(positive regulation of interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029840|interpro:IPR036236|reactome:R-HSA-9616222|refseq:NP_001120688.1|refseq:NP_005254.2|refseq:NP_001120687.1|dip:DIP-38452N|refseq:XP_011539547.1|refseq:XP_011539548.1|refseq:XP_005270806.1 - - - figure legend:2 B, C|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/12/07 2014/10/16 rogid:l5HpR5SwbKwqzy6a/WUkwnKVkck10090 rogid:BFND3tswCN4YNWrz8KZQeS0EZUw9606 intact-crc:BABBB750F1C21A83|rigid:qVkdyv8UI85Ei82QrckXHX9Naoc false sufficient binding region:398-593 sufficient binding region:1-20|mutation disrupting interaction:5-5,6-6,7-7|mutation disrupting interaction:10-10,11-11|mutation disrupting interaction:5-5 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91XC0 uniprotkb:Q99684 intact:EBI-1565930|uniprotkb:P97472|ensembl:ENSMUSP00000056977 intact:EBI-949368|ensembl:ENSP00000294702|ensembl:ENSP00000359357|ensembl:ENSP00000399719|uniprotkb:Q8N564 psi-mi:ajuba_mouse(display_long)|uniprotkb:Ajuba(gene name)|psi-mi:Ajuba(display_short)|uniprotkb:Jub(gene name synonym) psi-mi:gfi1_human(display_long)|uniprotkb:Growth factor independent protein 1(gene name synonym)|uniprotkb:Zinc finger protein 163(gene name synonym)|uniprotkb:GFI1(gene name)|psi-mi:GFI1(display_short)|uniprotkb:ZNF163(gene name synonym) psi-mi:"MI:0018"(two hybrid) Ayyanathan et al. (2007) pubmed:17909014|imex:IM-18884 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1566055|imex:IM-18884-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034720.2|dip:DIP-38451N|ensembl:ENSMUSG00000022178(gene)|ensembl:ENSMUST00000054487(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000932"(P-body)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031328"(positive regulation of cellular biosynthetic process)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035313"(wound healing, spreading of epidermal cells)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001781(Zinc finger, LIM-type)|reactome:R-MMU-1234176|reactome:R-MMU-2565942 ensembl:ENSG00000162676(gene)|ensembl:ENST00000294702(transcript)|ensembl:ENST00000370332(transcript)|ensembl:ENST00000427103(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070105"(positive regulation of interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029840|interpro:IPR036236|reactome:R-HSA-9616222|refseq:NP_001120688.1|refseq:NP_005254.2|refseq:NP_001120687.1|dip:DIP-38452N|refseq:XP_011539547.1|refseq:XP_011539548.1|refseq:XP_005270806.1 - - - figure legend:2 B, C|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/12/07 2014/10/16 rogid:T6AUE1QVamCFkotRwItOeD2IyLY10090 rogid:BFND3tswCN4YNWrz8KZQeS0EZUw9606 intact-crc:A35D47A2051B0766|rigid:JINKMMmrqyQF9VnKjmuAcKo9fAI false sufficient binding region:301-468 sufficient binding region:1-20|mutation disrupting interaction:5-5,6-6,7-7|mutation disrupting interaction:10-10,11-11|mutation disrupting interaction:5-5 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q91XC0 uniprotkb:Q99684 intact:EBI-1565930|uniprotkb:P97472|ensembl:ENSMUSP00000056977 intact:EBI-949368|ensembl:ENSP00000294702|ensembl:ENSP00000359357|ensembl:ENSP00000399719|uniprotkb:Q8N564 psi-mi:ajuba_mouse(display_long)|uniprotkb:Ajuba(gene name)|psi-mi:Ajuba(display_short)|uniprotkb:Jub(gene name synonym) psi-mi:gfi1_human(display_long)|uniprotkb:Growth factor independent protein 1(gene name synonym)|uniprotkb:Zinc finger protein 163(gene name synonym)|uniprotkb:GFI1(gene name)|psi-mi:GFI1(display_short)|uniprotkb:ZNF163(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ayyanathan et al. (2007) pubmed:17909014|imex:IM-18884 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1566079|imex:IM-18884-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034720.2|dip:DIP-38451N|ensembl:ENSMUSG00000022178(gene)|ensembl:ENSMUST00000054487(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000932"(P-body)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031328"(positive regulation of cellular biosynthetic process)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035313"(wound healing, spreading of epidermal cells)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001781(Zinc finger, LIM-type)|reactome:R-MMU-1234176|reactome:R-MMU-2565942 ensembl:ENSG00000162676(gene)|ensembl:ENST00000294702(transcript)|ensembl:ENST00000370332(transcript)|ensembl:ENST00000427103(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070105"(positive regulation of interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029840|interpro:IPR036236|reactome:R-HSA-9616222|refseq:NP_001120688.1|refseq:NP_005254.2|refseq:NP_001120687.1|dip:DIP-38452N|refseq:XP_011539547.1|refseq:XP_011539548.1|refseq:XP_005270806.1 - - - figure legend:3 A|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2007/12/07 2014/10/16 rogid:T6AUE1QVamCFkotRwItOeD2IyLY10090 rogid:BFND3tswCN4YNWrz8KZQeS0EZUw9606 intact-crc:80FC432F6FA76B8E|rigid:JINKMMmrqyQF9VnKjmuAcKo9fAI false myc tag:?-? mutation disrupting interaction:10-10,11-11|tag:?-?|mutation disrupting interaction:5-5,6-6,7-7|mutation disrupting interaction:5-5|sufficient binding region:1-20 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q91XC0 uniprotkb:Q99684 intact:EBI-1565930|uniprotkb:P97472|ensembl:ENSMUSP00000056977 intact:EBI-949368|ensembl:ENSP00000294702|ensembl:ENSP00000359357|ensembl:ENSP00000399719|uniprotkb:Q8N564 psi-mi:ajuba_mouse(display_long)|uniprotkb:Ajuba(gene name)|psi-mi:Ajuba(display_short)|uniprotkb:Jub(gene name synonym) psi-mi:gfi1_human(display_long)|uniprotkb:Growth factor independent protein 1(gene name synonym)|uniprotkb:Zinc finger protein 163(gene name synonym)|uniprotkb:GFI1(gene name)|psi-mi:GFI1(display_short)|uniprotkb:ZNF163(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Ayyanathan et al. (2007) pubmed:17909014|imex:IM-18884 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-1566111|imex:IM-18884-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034720.2|dip:DIP-38451N|ensembl:ENSMUSG00000022178(gene)|ensembl:ENSMUST00000054487(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000932"(P-body)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031328"(positive regulation of cellular biosynthetic process)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035313"(wound healing, spreading of epidermal cells)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001781(Zinc finger, LIM-type)|reactome:R-MMU-1234176|reactome:R-MMU-2565942 ensembl:ENSG00000162676(gene)|ensembl:ENST00000294702(transcript)|ensembl:ENST00000370332(transcript)|ensembl:ENST00000427103(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070105"(positive regulation of interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029840|interpro:IPR036236|reactome:R-HSA-9616222|refseq:NP_001120688.1|refseq:NP_005254.2|refseq:NP_001120687.1|dip:DIP-38452N|refseq:XP_011539547.1|refseq:XP_011539548.1|refseq:XP_005270806.1 - - - figure legend:4 B|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2007/12/07 2014/10/16 rogid:T6AUE1QVamCFkotRwItOeD2IyLY10090 rogid:BFND3tswCN4YNWrz8KZQeS0EZUw9606 intact-crc:60C4FAFB55E81012|rigid:JINKMMmrqyQF9VnKjmuAcKo9fAI false myc tag:?-? sufficient binding region:1-20|mutation disrupting interaction:5-5,6-6,7-7|mutation disrupting interaction:5-5|tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)