#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P48023	uniprotkb:Q99JB8	intact:EBI-495538|uniprotkb:Q9BZP9|ensembl:ENSP00000356694	intact:EBI-77834|ensembl:ENSMUSP00000028694|ensembl:ENSMUSP00000054391|ensembl:ENSMUSP00000106981|ensembl:ENSMUSP00000129175|uniprotkb:Q9EQP9	psi-mi:tnfl6_human(display_long)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:CD95L(gene name synonym)|uniprotkb:Apoptosis antigen ligand(gene name synonym)|uniprotkb:FASLG(gene name)|psi-mi:FASLG(display_short)|uniprotkb:APT1LG1(gene name synonym)|uniprotkb:FASL(gene name synonym)|uniprotkb:TNFSF6(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)	psi-mi:pacn3_mouse(display_long)|uniprotkb:Pacsin3(gene name)|psi-mi:Pacsin3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Thornhill et al. (2007)	pubmed:17761170|imex:IM-11376|mint:MINT-5220145	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7583563|mint:MINT-5209472|imex:IM-11376-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000630.1|refseq:NP_001289675.1|dip:DIP-2997N|ensembl:ENSG00000117560(gene)|ensembl:ENST00000367721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1903514"(release of sequestered calcium ion into cytosol by endoplasmic reticulum)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR028326|mint:P48023|rcsb pdb:1BZI|rcsb pdb:4MSV|rcsb pdb:5L19|rcsb pdb:5L36|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6785807|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-8862803|reactome:R-HSA-9614657|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0070848"(response to growth factor)|mint:MINT-5209473(identity)	ensembl:ENSMUSG00000027257(gene)|ensembl:ENSMUST00000028694(transcript)|ensembl:ENSMUST00000059566(transcript)|ensembl:ENSMUST00000111349(transcript)|ensembl:ENSMUST00000168916(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008289"(lipid binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028523|interpro:IPR031160|interpro:IPR036028|mint:Q99JB8|rcsb pdb:3M3W|rcsb pdb:3QE6|rcsb pdb:3SYV|reactome:R-MMU-8856828|refseq:NP_083009.1|refseq:NP_112019.2|refseq:XP_006500487.1|refseq:XP_006500488.1|refseq:XP_006500490.1|refseq:XP_006500491.1|refseq:NP_001276606.1|refseq:NP_001276607.1|mint:MINT-5209474(identity)	-	-	-	figure legend:T1|figure legend:F2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-schwann)|taxid:10090(Mus musculus)	-	2007/10/23	2014/10/16	rogid:3/Op+1mSXMoGr/8mhnh1oCpQ4sQ9606	rogid:cm01D0WJAwAupYJ64NRxTeFC79U10090	intact-crc:0EABB3830A07A954|rigid:RgfHEb1SzjjhbKz5JRS62ZfM/78	false	flag tag:?-?(MINT-5209484)|mutation increasing interaction:2-33(MINT-5209487)	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P48023	uniprotkb:Q9WVE8	intact:EBI-495538|uniprotkb:Q9BZP9|ensembl:ENSP00000356694	intact:EBI-645729|ensembl:ENSMUSP00000058320|ensembl:ENSMUSP00000130098|ensembl:ENSMUSP00000131504|ensembl:ENSMUSP00000155334|ensembl:ENSMUSP00000155481	psi-mi:tnfl6_human(display_long)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:CD95L(gene name synonym)|uniprotkb:Apoptosis antigen ligand(gene name synonym)|uniprotkb:FASLG(gene name)|psi-mi:FASLG(display_short)|uniprotkb:APT1LG1(gene name synonym)|uniprotkb:FASL(gene name synonym)|uniprotkb:TNFSF6(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)	psi-mi:pacn2_mouse(display_long)|uniprotkb:Pacsin2(gene name)|psi-mi:Pacsin2(display_short)|uniprotkb:Syndapin-II(gene name synonym)|uniprotkb:Syndapin-2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Thornhill et al. (2007)	pubmed:17761170|imex:IM-11376|mint:MINT-5220145	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7583563|mint:MINT-5209472|imex:IM-11376-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000630.1|refseq:NP_001289675.1|dip:DIP-2997N|ensembl:ENSG00000117560(gene)|ensembl:ENST00000367721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1903514"(release of sequestered calcium ion into cytosol by endoplasmic reticulum)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR028326|mint:P48023|rcsb pdb:1BZI|rcsb pdb:4MSV|rcsb pdb:5L19|rcsb pdb:5L36|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6785807|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-8862803|reactome:R-HSA-9614657|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0070848"(response to growth factor)|mint:MINT-5209473(identity)	refseq:NP_001152981.1|refseq:NP_001152982.1|refseq:NP_035992.1|ensembl:ENSMUSG00000016664(gene)|ensembl:ENSMUST00000056177(transcript)|ensembl:ENSMUST00000165095(transcript)|ensembl:ENSMUST00000171436(transcript)|ensembl:ENSMUST00000230679(transcript)|ensembl:ENSMUST00000231184(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0032587"(ruffle membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0070836"(caveola assembly)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028521|interpro:IPR031160|interpro:IPR035743|interpro:IPR036028|interpro:IPR037453|mint:Q9WVE8|rcsb pdb:3LLL|reactome:R-MMU-8856828|go:"GO:0019898"(extrinsic component of membrane)|mint:MINT-5209475(identity)	-	-	-	figure legend:T1|figure legend:F2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-schwann)|taxid:10090(Mus musculus)	-	2007/10/23	2014/10/16	rogid:3/Op+1mSXMoGr/8mhnh1oCpQ4sQ9606	rogid:5ZzVQRaqMbqn/kBzGkCvQSUX5qs10090	intact-crc:0EABB3830A07A954|rigid:RgfHEb1SzjjhbKz5JRS62ZfM/78	false	flag tag:?-?(MINT-5209484)|mutation increasing interaction:2-33(MINT-5209487)	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P48023	uniprotkb:Q9DBG3	intact:EBI-495538|uniprotkb:Q9BZP9|ensembl:ENSP00000356694	intact:EBI-775229|uniprotkb:Q80XJ4|ensembl:ENSMUSP00000070714	psi-mi:tnfl6_human(display_long)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:CD95L(gene name synonym)|uniprotkb:Apoptosis antigen ligand(gene name synonym)|uniprotkb:FASLG(gene name)|psi-mi:FASLG(display_short)|uniprotkb:APT1LG1(gene name synonym)|uniprotkb:FASL(gene name synonym)|uniprotkb:TNFSF6(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)	psi-mi:ap2b1_mouse(display_long)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Ap2b1(gene name)|psi-mi:Ap2b1(display_short)|uniprotkb:Clapb1(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Thornhill et al. (2007)	pubmed:17761170|imex:IM-11376|mint:MINT-5220145	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7583563|mint:MINT-5209472|imex:IM-11376-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000630.1|refseq:NP_001289675.1|dip:DIP-2997N|ensembl:ENSG00000117560(gene)|ensembl:ENST00000367721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1903514"(release of sequestered calcium ion into cytosol by endoplasmic reticulum)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR028326|mint:P48023|rcsb pdb:1BZI|rcsb pdb:4MSV|rcsb pdb:5L19|rcsb pdb:5L36|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6785807|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-8862803|reactome:R-HSA-9614657|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0070848"(response to growth factor)|mint:MINT-5209473(identity)	refseq:NP_001030931.1|refseq:NP_082191.1|refseq:XP_006534321.1|refseq:XP_017170261.1|dip:DIP-32161N|ensembl:ENSMUSG00000035152(gene)|ensembl:ENSMUST00000065692(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0003279"(cardiac septum development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007507"(heart development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0035904"(aorta development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099590"(neurotransmitter receptor internalization)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905477"(positive regulation of protein localization to membrane)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:Q9DBG3|rcsb pdb:6OWO|rcsb pdb:6OXL|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038|mint:MINT-5209477(identity)	-	-	-	figure legend:T1|figure legend:F2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-schwann)|taxid:10090(Mus musculus)	-	2007/10/23	2014/10/16	rogid:3/Op+1mSXMoGr/8mhnh1oCpQ4sQ9606	rogid:YWwOqRpXCJDwzrLv27muBx1+DHI10090	intact-crc:0EABB3830A07A954|rigid:RgfHEb1SzjjhbKz5JRS62ZfM/78	false	flag tag:?-?(MINT-5209484)|mutation increasing interaction:2-33(MINT-5209487)	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P48023	uniprotkb:Q91ZR2	intact:EBI-495538|uniprotkb:Q9BZP9|ensembl:ENSP00000356694	intact:EBI-6879954	psi-mi:tnfl6_human(display_long)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:CD95L(gene name synonym)|uniprotkb:Apoptosis antigen ligand(gene name synonym)|uniprotkb:FASLG(gene name)|psi-mi:FASLG(display_short)|uniprotkb:APT1LG1(gene name synonym)|uniprotkb:FASL(gene name synonym)|uniprotkb:TNFSF6(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)	psi-mi:snx18_mouse(display_long)|uniprotkb:Snx18(gene name)|psi-mi:Snx18(display_short)|uniprotkb:Snag1(gene name synonym)|uniprotkb:Sorting nexin-associated Golgi protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Thornhill et al. (2007)	pubmed:17761170|imex:IM-11376|mint:MINT-5220145	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7583563|mint:MINT-5209472|imex:IM-11376-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000630.1|refseq:NP_001289675.1|dip:DIP-2997N|ensembl:ENSG00000117560(gene)|ensembl:ENST00000367721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1903514"(release of sequestered calcium ion into cytosol by endoplasmic reticulum)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR028326|mint:P48023|rcsb pdb:1BZI|rcsb pdb:4MSV|rcsb pdb:5L19|rcsb pdb:5L36|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6785807|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-8862803|reactome:R-HSA-9614657|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0070848"(response to growth factor)|mint:MINT-5209473(identity)	interpro:IPR035557|interpro:IPR035703|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030426"(growth cone)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0070062"(extracellular exosome)|reactome:R-MMU-8856828|interpro:IPR001683(Phox-like)|interpro:IPR001452(Src homology-3)|interpro:IPR019497|mint:Q91ZR2|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR027267|interpro:IPR036028|interpro:IPR036871|interpro:IPR028646|mint:MINT-5209476(identity)	-	-	-	figure legend:T1|figure legend:F2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-schwann)|taxid:10090(Mus musculus)	-	2007/10/23	2014/10/16	rogid:3/Op+1mSXMoGr/8mhnh1oCpQ4sQ9606	rogid:IPItUfL1UtHEriGBWsVef917RSM10090	intact-crc:0EABB3830A07A954|rigid:RgfHEb1SzjjhbKz5JRS62ZfM/78	false	flag tag:?-?(MINT-5209484)|mutation increasing interaction:2-33(MINT-5209487)	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P48023	uniprotkb:Q9DBG3	intact:EBI-495538|uniprotkb:Q9BZP9|ensembl:ENSP00000356694	intact:EBI-775229|uniprotkb:Q80XJ4|ensembl:ENSMUSP00000070714	psi-mi:tnfl6_human(display_long)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:CD95L(gene name synonym)|uniprotkb:Apoptosis antigen ligand(gene name synonym)|uniprotkb:FASLG(gene name)|psi-mi:FASLG(display_short)|uniprotkb:APT1LG1(gene name synonym)|uniprotkb:FASL(gene name synonym)|uniprotkb:TNFSF6(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)	psi-mi:ap2b1_mouse(display_long)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Ap2b1(gene name)|psi-mi:Ap2b1(display_short)|uniprotkb:Clapb1(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Thornhill et al. (2007)	pubmed:17761170|imex:IM-11376|mint:MINT-5220145	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7583636|mint:MINT-5209498|imex:IM-11376-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000630.1|refseq:NP_001289675.1|dip:DIP-2997N|ensembl:ENSG00000117560(gene)|ensembl:ENST00000367721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1903514"(release of sequestered calcium ion into cytosol by endoplasmic reticulum)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR028326|mint:P48023|rcsb pdb:1BZI|rcsb pdb:4MSV|rcsb pdb:5L19|rcsb pdb:5L36|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6785807|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-8862803|reactome:R-HSA-9614657|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0070848"(response to growth factor)|mint:MINT-5209499(identity)	refseq:NP_001030931.1|refseq:NP_082191.1|refseq:XP_006534321.1|refseq:XP_017170261.1|dip:DIP-32161N|ensembl:ENSMUSG00000035152(gene)|ensembl:ENSMUST00000065692(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0003279"(cardiac septum development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007507"(heart development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0035904"(aorta development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099590"(neurotransmitter receptor internalization)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905477"(positive regulation of protein localization to membrane)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:Q9DBG3|rcsb pdb:6OWO|rcsb pdb:6OXL|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038|mint:MINT-5209511(identity)	-	-	-	figure legend:F3A|figure legend:F3C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-schwann)|taxid:10090(Mus musculus)	-	2007/10/23	2014/10/16	rogid:3/Op+1mSXMoGr/8mhnh1oCpQ4sQ9606	rogid:YWwOqRpXCJDwzrLv27muBx1+DHI10090	intact-crc:76924D706115025D|rigid:Lsw60Php3tlSFOaNccpcwXW1Z5o	false	mutation increasing interaction:2-70(MINT-5209500)|flag tag:?-?(MINT-5209502)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q91ZR2	uniprotkb:P48023	intact:EBI-6879954	intact:EBI-495538|uniprotkb:Q9BZP9|ensembl:ENSP00000356694	psi-mi:snx18_mouse(display_long)|uniprotkb:Snx18(gene name)|psi-mi:Snx18(display_short)|uniprotkb:Snag1(gene name synonym)|uniprotkb:Sorting nexin-associated Golgi protein 1(gene name synonym)	psi-mi:tnfl6_human(display_long)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:CD95L(gene name synonym)|uniprotkb:Apoptosis antigen ligand(gene name synonym)|uniprotkb:FASLG(gene name)|psi-mi:FASLG(display_short)|uniprotkb:APT1LG1(gene name synonym)|uniprotkb:FASL(gene name synonym)|uniprotkb:TNFSF6(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Thornhill et al. (2007)	pubmed:17761170|imex:IM-11376|mint:MINT-5220145	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7583698|mint:MINT-5209533|imex:IM-11376-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR035557|interpro:IPR035703|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030426"(growth cone)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0070062"(extracellular exosome)|reactome:R-MMU-8856828|interpro:IPR001683(Phox-like)|interpro:IPR001452(Src homology-3)|interpro:IPR019497|mint:Q91ZR2|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR027267|interpro:IPR036028|interpro:IPR036871|interpro:IPR028646|mint:MINT-5209540(identity)	refseq:NP_000630.1|refseq:NP_001289675.1|dip:DIP-2997N|ensembl:ENSG00000117560(gene)|ensembl:ENST00000367721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1903514"(release of sequestered calcium ion into cytosol by endoplasmic reticulum)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR028326|mint:P48023|rcsb pdb:1BZI|rcsb pdb:4MSV|rcsb pdb:5L19|rcsb pdb:5L36|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6785807|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-8862803|reactome:R-HSA-9614657|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0070848"(response to growth factor)|mint:MINT-5209534(identity)	-	-	-	figure legend:F4|figure legend:F5B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-schwann)|taxid:10090(Mus musculus)	-	2007/10/23	2014/10/16	rogid:IPItUfL1UtHEriGBWsVef917RSM10090	rogid:3/Op+1mSXMoGr/8mhnh1oCpQ4sQ9606	intact-crc:8747417CA48EA73D|rigid:e1BA/V4PQ1kjlQi9xWGKnrPWFL0	false	-	flag tag:?-?(MINT-5209535)|mutation increasing interaction:33-70(MINT-5209537)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P48023	uniprotkb:Q91ZR2	intact:EBI-495538|uniprotkb:Q9BZP9|ensembl:ENSP00000356694	intact:EBI-6879954	psi-mi:tnfl6_human(display_long)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:CD95L(gene name synonym)|uniprotkb:Apoptosis antigen ligand(gene name synonym)|uniprotkb:FASLG(gene name)|psi-mi:FASLG(display_short)|uniprotkb:APT1LG1(gene name synonym)|uniprotkb:FASL(gene name synonym)|uniprotkb:TNFSF6(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)	psi-mi:snx18_mouse(display_long)|uniprotkb:Snx18(gene name)|psi-mi:Snx18(display_short)|uniprotkb:Snag1(gene name synonym)|uniprotkb:Sorting nexin-associated Golgi protein 1(gene name synonym)	psi-mi:"MI:0089"(protein array)	Thornhill et al. (2007)	pubmed:17761170|imex:IM-11376|mint:MINT-5220145	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7583729|mint:MINT-5209548|imex:IM-11376-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000630.1|refseq:NP_001289675.1|dip:DIP-2997N|ensembl:ENSG00000117560(gene)|ensembl:ENST00000367721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1903514"(release of sequestered calcium ion into cytosol by endoplasmic reticulum)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR028326|mint:P48023|rcsb pdb:1BZI|rcsb pdb:4MSV|rcsb pdb:5L19|rcsb pdb:5L36|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6785807|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-8862803|reactome:R-HSA-9614657|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0070848"(response to growth factor)|mint:MINT-5209549(identity)	interpro:IPR035557|interpro:IPR035703|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030426"(growth cone)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0070062"(extracellular exosome)|reactome:R-MMU-8856828|interpro:IPR001683(Phox-like)|interpro:IPR001452(Src homology-3)|interpro:IPR019497|mint:Q91ZR2|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR027267|interpro:IPR036028|interpro:IPR036871|interpro:IPR028646|mint:MINT-5209555(identity)	-	-	-	figure legend:F5A|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/10/23	2014/10/16	rogid:3/Op+1mSXMoGr/8mhnh1oCpQ4sQ9606	rogid:IPItUfL1UtHEriGBWsVef917RSM10090	intact-crc:FD3AF29E68337FB9|rigid:e1BA/V4PQ1kjlQi9xWGKnrPWFL0	false	binding-associated region:33-45(MINT-5209568)	binding-associated region:3-59(MINT-5209572)|glutathione s tranferase tag:?-?(MINT-5209561)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48023	uniprotkb:Q91ZR2	intact:EBI-495538|uniprotkb:Q9BZP9|ensembl:ENSP00000356694	intact:EBI-6879954	psi-mi:tnfl6_human(display_long)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:CD95L(gene name synonym)|uniprotkb:Apoptosis antigen ligand(gene name synonym)|uniprotkb:FASLG(gene name)|psi-mi:FASLG(display_short)|uniprotkb:APT1LG1(gene name synonym)|uniprotkb:FASL(gene name synonym)|uniprotkb:TNFSF6(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)	psi-mi:snx18_mouse(display_long)|uniprotkb:Snx18(gene name)|psi-mi:Snx18(display_short)|uniprotkb:Snag1(gene name synonym)|uniprotkb:Sorting nexin-associated Golgi protein 1(gene name synonym)	psi-mi:"MI:0089"(protein array)	Thornhill et al. (2007)	pubmed:17761170|imex:IM-11376|mint:MINT-5220145	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7583772|mint:MINT-5209576|imex:IM-11376-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000630.1|refseq:NP_001289675.1|dip:DIP-2997N|ensembl:ENSG00000117560(gene)|ensembl:ENST00000367721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1903514"(release of sequestered calcium ion into cytosol by endoplasmic reticulum)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR028326|mint:P48023|rcsb pdb:1BZI|rcsb pdb:4MSV|rcsb pdb:5L19|rcsb pdb:5L36|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6785807|reactome:R-HSA-69416|reactome:R-HSA-75157|reactome:R-HSA-8862803|reactome:R-HSA-9614657|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0070848"(response to growth factor)|mint:MINT-5209577(identity)	interpro:IPR035557|interpro:IPR035703|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030426"(growth cone)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0070062"(extracellular exosome)|reactome:R-MMU-8856828|interpro:IPR001683(Phox-like)|interpro:IPR001452(Src homology-3)|interpro:IPR019497|mint:Q91ZR2|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR027267|interpro:IPR036028|interpro:IPR036871|interpro:IPR028646|mint:MINT-5209581(identity)	-	-	-	figure legend:F5A|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/10/23	2014/10/16	rogid:3/Op+1mSXMoGr/8mhnh1oCpQ4sQ9606	rogid:IPItUfL1UtHEriGBWsVef917RSM10090	intact-crc:64F59E6B842F69E7|rigid:e1BA/V4PQ1kjlQi9xWGKnrPWFL0	false	binding-associated region:61-73(MINT-5209578)	binding-associated region:3-59(MINT-5209582)|glutathione s tranferase tag:?-?(MINT-5209585)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)