#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P41809 uniprotkb:P40073 intact:EBI-8364|uniprotkb:Q04051|uniprotkb:D6VT50|ensemblfungi:YDR420W intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C psi-mi:hkr1_yeast(display_long)|uniprotkb:YDR420W(locus name)|uniprotkb:HKR1(gene name)|psi-mi:HKR1(display_short)|uniprotkb:Hansenula MRAKII killer toxin-resistant protein 1(gene name synonym) psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Tatebayashi et al. (2007) pubmed:17627274|imex:IM-11366|mint:MINT-5223580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7491462|mint:MINT-5225247|imex:IM-11366-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010708.1|sgd:S000002828|mint:P41809|interpro:IPR039295|ensemblfungi:YDR420W(gene)|ensemblfungi:YDR420W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006075"("(1->3)-beta-D-glucan biosynthetic process")|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0009986"(cell surface)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|mint:MINT-5225249(identity) refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073|mint:MINT-5225250(identity) - - crc64:E467A4D50AA3EDB6 figure legend:f6e|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/26 2014/10/16 rogid:3L+LNEsSp2LXueSY+HVvf2lBKZE559292 rogid:DPpJB36kZxbFXugXajgs899epuY559292 intact-crc:E3F4156FEEFA202A|rigid:2d8rq9LSe2/37SQpDy5rqAgd9G4 false ha tag:?-?(MINT-5225257) mutation decreasing interaction:106-106(MINT-5225275)|glutathione s tranferase tag:?-?(MINT-5225253)|mutation decreasing interaction:108-108(MINT-5225278) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32334 uniprotkb:P40073 intact:EBI-11328|uniprotkb:D6VUF0|ensemblfungi:YGR014W intact:EBI-18140|uniprotkb:D3DM24|ensemblfungi:YER118C psi-mi:msb2_yeast(display_long)|uniprotkb:MSB2(gene name)|psi-mi:MSB2(display_short)|uniprotkb:Multicopy suppressor of bud emergence 2(gene name synonym)|uniprotkb:Osmosensor MSB2(gene name synonym)|uniprotkb:YGR014W(locus name) psi-mi:sho1_yeast(display_long)|uniprotkb:YER118C(locus name)|uniprotkb:SHO1(gene name)|psi-mi:SHO1(display_short)|uniprotkb:SSU81(gene name synonym)|uniprotkb:Osmosensor SHO1(gene name synonym)|uniprotkb:Suppressor of SUA8-1 mutation(gene name synonym)|uniprotkb:Synthetic high osmolarity-sensitive protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Tatebayashi et al. (2007) pubmed:17627274|imex:IM-11366|mint:MINT-5223580 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7491489|mint:MINT-5225261|imex:IM-11366-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR014W(gene)|ensemblfungi:YGR014W_mRNA(transcript)|go:"GO:0000282"(cellular bud site selection)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007232"(osmosensory signaling pathway via Sho1 osmosensor)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR039295|go:"GO:0009986"(cell surface)|refseq:NP_011528.3|sgd:S000003246|mint:P32334|dip:DIP-1455N|mint:MINT-5225268(identity) refseq:NP_011043.1|sgd:S000000920|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044697"(HICS complex)|go:"GO:0071944"(cell periphery)|interpro:IPR001452(Src homology-3)|interpro:IPR035522|interpro:IPR036028|ensemblfungi:YER118C(gene)|interpro:IPR039644|rcsb pdb:2VKN|ensemblfungi:YER118C_mRNA(transcript)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0005034"(osmosensor activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-2472N|mint:P40073|mint:MINT-5225263(identity) - - crc64:E467A4D50AA3EDB6 figure legend:f6e|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/26 2014/10/16 rogid:UsebPCw3sBOg1xeiMmr80m7b4P4559292 rogid:DPpJB36kZxbFXugXajgs899epuY559292 intact-crc:C5AA62F513C48525|rigid:UnId6tCUDzOWpKnnKWU5uZLyWuc false ha tag:?-?(MINT-5225269) mutation decreasing interaction:106-106(MINT-5225282)|mutation decreasing interaction:108-108(MINT-5225285)|glutathione s tranferase tag:?-?(MINT-5225264) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant)