#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9QUI0	uniprotkb:P46414	intact:EBI-643583|uniprotkb:O88336|ensembl:ENSMUSP00000007959	intact:EBI-1005742|ensembl:ENSMUSP00000003115|ensembl:ENSMUSP00000065832|ensembl:ENSMUSP00000145056|uniprotkb:Q8BG74	psi-mi:rhoa_mouse(display_long)|uniprotkb:Rhoa(gene name)|psi-mi:Rhoa(display_short)|uniprotkb:Arha(gene name synonym)|uniprotkb:Arha2(gene name synonym)	psi-mi:cdn1b_mouse(display_long)|uniprotkb:Cyclin-dependent kinase inhibitor p27(gene name synonym)|uniprotkb:p27Kip1(gene name synonym)|uniprotkb:Cdkn1b(gene name)|psi-mi:Cdkn1b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Papakonstanti et al. (2007)	pubmed:17581634|imex:IM-11238|mint:MINT-5220041	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7467584|mint:MINT-4981092|imex:IM-11238-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_058082.2|refseq:NP_001300890.1|refseq:NP_001300891.1|ensembl:ENSMUST00000007959(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001822"(kidney development)|go:"GO:0001998"(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:"GO:0002363"(alpha-beta T cell lineage commitment)|go:"GO:0003100"(regulation of systemic arterial blood pressure by endothelin)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|ensembl:ENSMUSG00000007815(gene)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0030496"(midbody)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031098"(stress-activated protein kinase signaling cascade)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0009749"(response to glucose)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033688"(regulation of osteoblast proliferation)|go:"GO:0034329"(cell junction assembly)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0038027"(apolipoprotein A-I-mediated signaling pathway)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0042995"(cell projection)|go:"GO:0016020"(membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043197"(dendritic spine)|go:"GO:0043200"(response to amino acid)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0016477"(cell migration)|go:"GO:0017022"(myosin binding)|go:"GO:0019003"(GDP binding)|go:"GO:0043366"(beta selection)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045471"(response to ethanol)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0071944"(cell periphery)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0090324"(negative regulation of oxidative phosphorylation)|go:"GO:0097498"(endothelial tube lumen extension)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:1902766"(skeletal muscle satellite cell migration)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903673"(mitotic cleavage furrow formation)|go:"GO:1904695"(positive regulation of vascular associated smooth muscle contraction)|go:"GO:0046039"(GTP metabolic process)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:1905244"(regulation of modification of synaptic structure)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|go:"GO:0048812"(neuron projection morphogenesis)|mint:Q9QUI0|rcsb pdb:4F38|reactome:R-MMU-114604|reactome:R-MMU-193634|reactome:R-MMU-198203|reactome:R-MMU-209563|reactome:R-MMU-2173791|reactome:R-MMU-392451|reactome:R-MMU-3928662|reactome:R-MMU-3928663|reactome:R-MMU-4086400|reactome:R-MMU-416482|go:"GO:0050773"(regulation of dendrite development)|reactome:R-MMU-416550|reactome:R-MMU-416572|reactome:R-MMU-4420097|reactome:R-MMU-5625740|reactome:R-MMU-5625900|reactome:R-MMU-5625970|reactome:R-MMU-5627117|reactome:R-MMU-5663220|reactome:R-MMU-5666185|reactome:R-MMU-5689896|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|reactome:R-MMU-6785631|go:"GO:0051384"(response to glucocorticoid)|reactome:R-MMU-6798695|go:"GO:0051496"(positive regulation of stress fiber assembly)|reactome:R-MMU-8849471|reactome:R-MMU-8980692|reactome:R-MMU-8985586|reactome:R-MMU-9013106|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060193"(positive regulation of lipase activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061383"(trabecula morphogenesis)|dip:DIP-29984N|mint:MINT-4981093(identity)	ensembl:ENSMUSG00000003031(gene)|ensembl:ENSMUST00000003115(transcript)|ensembl:ENSMUST00000067327(transcript)|ensembl:ENSMUST00000204807(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001890"(placenta development)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008219"(cell death)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009749"(response to glucose)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0043200"(response to amino acid)|go:"GO:0051087"(chaperone binding)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1902746"(regulation of lens fiber cell differentiation)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029843|mint:P46414|reactome:R-MMU-187577|reactome:R-MMU-198323|reactome:R-MMU-2559582|reactome:R-MMU-2559586|reactome:R-MMU-6804116|reactome:R-MMU-69202|reactome:R-MMU-69231|go:"GO:0045732"(positive regulation of protein catabolic process)|reactome:R-MMU-69563|reactome:R-MMU-69656|reactome:R-MMU-8849470|reactome:R-MMU-9607240|reactome:R-MMU-9634638|refseq:NP_034005.2|dip:DIP-445N|mint:MINT-4981117(identity)	-	-	-	figure legend:F6B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-bmm)|taxid:10090(mouse bone marrow derived macrophages)	-	2007/09/11	2014/10/16	rogid:HKBQaI187g5GnvTF9bilOaiTaXM10090	rogid:erDk73bbQbO3Bz4XfOL4EAo463010090	intact-crc:088AB0659ACB6290|rigid:Z2O81RZhzSL30DDtetsR1njMalQ	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0113"(western blot)