#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:A5J090	uniprotkb:Q9PUK8	intact:EBI-7401819|intact:MINT-4821054	intact:EBI-6925794|uniprotkb:Q9IB13|uniprotkb:Q9PWN7|uniprotkb:Q9W703|uniprotkb:Q9W743	psi-mi:a5j090_xenla(display_long)	psi-mi:fzd7a_xenla(display_long)|uniprotkb:fzd7-a(gene name)|psi-mi:fzd7-a(display_short)|uniprotkb:fz7-a(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kim et al. (2007)	pubmed:17476309|imex:IM-11049|mint:MINT-5219908	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7402006|mint:MINT-4821074|imex:IM-11049-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR014752(Arrestin, C-terminal)|mint:A5J090|interpro:IPR017864|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR000698(Arrestin)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR014753(Arrestin, N-terminal)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|mint:MINT-4821076(identity)	go:"GO:0001707"(mesoderm formation)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008104"(protein localization)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0045545"(syndecan binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060070"(canonical Wnt signaling pathway)|refseq:NP_001079354.1|interpro:IPR000539(Frizzled protein)|interpro:IPR015526(Frizzled related)|interpro:IPR020067|interpro:IPR026552|interpro:IPR017981|mint:Q9PUK8|interpro:IPR036790|interpro:IPR042742|mint:MINT-4821110(identity)	-	comment:mint	-	figure legend:F3E|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293ft)|taxid:9606(Homo sapiens HEK293FT cell line)	-	2007/07/11	2014/10/16	rogid:4KqD4JrD5D19rKv+pB79yMDjrgU8355	rogid:u18KrCLP74ZnRqTejeQ7P4HpxSY8355	intact-crc:ADE1F0516EF43DA3|rigid:7G5EKmbDHRpMPBRTL88hhAIb6gI	false	green fluorescent protein tag:?-?(MINT-4821079)	myc tag:?-?(MINT-4821111)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:A5J090	uniprotkb:P51142	intact:EBI-7401819|intact:MINT-4821054	intact:EBI-6257503	psi-mi:a5j090_xenla(display_long)	psi-mi:dvl2_xenla(display_long)|uniprotkb:dvl2(gene name)|psi-mi:dvl2(display_short)|uniprotkb:dsh(gene name synonym)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:Xdsh(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kim et al. (2007)	pubmed:17476309|imex:IM-11049|mint:MINT-5219908	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7402099|mint:MINT-4821271|imex:IM-11049-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR014752(Arrestin, C-terminal)|mint:A5J090|interpro:IPR017864|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR000698(Arrestin)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR014753(Arrestin, N-terminal)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|mint:MINT-4821272(identity)	go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0022008"(neurogenesis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045545"(syndecan binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0060026"(convergent extension)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060271"(cilium assembly)|go:"GO:0090630"(activation of GTPase activity)|rcsb pdb:1L6O|rcsb pdb:2F0A|rcsb pdb:3FY5|mint:P51142|refseq:NP_001084096.1|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR024580|interpro:IPR003351(Dishevelled protein)|interpro:IPR001158(DIX)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR029071|interpro:IPR038207|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|mint:MINT-4821278(identity)	-	comment:mint	-	figure legend:F5A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293ft)|taxid:9606(Homo sapiens HEK293FT cell line)	-	2007/07/11	2014/10/16	rogid:4KqD4JrD5D19rKv+pB79yMDjrgU8355	rogid:9sVQXQeFtWj/Vjbc/ABl3kHS5dE8355	intact-crc:58B6243AEC67BA12|rigid:gkFUHKN8F8amgKoagoYndSiRao8	false	ha tag:?-?(MINT-4821273)	myc tag:?-?(MINT-4821281)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q08464	uniprotkb:A5J090	intact:EBI-7402050|intact:MINT-1780823	intact:EBI-7401819|intact:MINT-4821054	psi-mi:fzd2_rat(display_long)|uniprotkb:Fzd2(gene name)|psi-mi:Fzd2(display_short)	psi-mi:a5j090_xenla(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kim et al. (2007)	pubmed:17476309|imex:IM-11049|mint:MINT-5219908	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7402044|mint:MINT-4821125|imex:IM-11049-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q08464|rgd:71012|refseq:NP_742032.1|interpro:IPR017981|interpro:IPR015526(Frizzled related)|interpro:IPR020067|interpro:IPR026550|interpro:IPR000539(Frizzled protein)|go:"GO:0001775"(cell activation)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003150"(muscular septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007199"(G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060022"(hard palate development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|reactome:R-RNO-4086398|reactome:R-RNO-4608870|reactome:R-RNO-4641262|reactome:R-RNO-5140745|go:"GO:0005886"(plasma membrane)|interpro:IPR036790|interpro:IPR041778|mint:MINT-4821132(identity)	interpro:IPR014752(Arrestin, C-terminal)|mint:A5J090|interpro:IPR017864|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR000698(Arrestin)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR014753(Arrestin, N-terminal)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|mint:MINT-4821126(identity)	-	comment:mint|function:Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activation by Wnt5A stimulates PKC activity via a G-protein-dependent mechanism	comment:mint	figure legend:F3E|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293ft)|taxid:9606(Homo sapiens HEK293FT cell line)	-	2007/07/11	2014/10/16	rogid:2EuU2YJ/z/lIjENrsYm2GzBtT4Q10116	rogid:4KqD4JrD5D19rKv+pB79yMDjrgU8355	intact-crc:18DC1B131B5B4AFB|rigid:cwmowk5J607Z77dNjQKcZpQuR7I	false	myc tag:?-?(MINT-4821135)	green fluorescent protein tag:?-?(MINT-4821127)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:A5J090	uniprotkb:P51142	intact:EBI-7401819|intact:MINT-4821054	intact:EBI-6257503	psi-mi:a5j090_xenla(display_long)	psi-mi:dvl2_xenla(display_long)|uniprotkb:dvl2(gene name)|psi-mi:dvl2(display_short)|uniprotkb:dsh(gene name synonym)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:Xdsh(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kim et al. (2007)	pubmed:17476309|imex:IM-11049|mint:MINT-5219908	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7402117|mint:MINT-4821292|imex:IM-11049-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR014752(Arrestin, C-terminal)|mint:A5J090|interpro:IPR017864|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR000698(Arrestin)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR014753(Arrestin, N-terminal)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|mint:MINT-4821293(identity)	go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0022008"(neurogenesis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045545"(syndecan binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0060026"(convergent extension)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060271"(cilium assembly)|go:"GO:0090630"(activation of GTPase activity)|rcsb pdb:1L6O|rcsb pdb:2F0A|rcsb pdb:3FY5|mint:P51142|refseq:NP_001084096.1|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR024580|interpro:IPR003351(Dishevelled protein)|interpro:IPR001158(DIX)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR029071|interpro:IPR038207|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|mint:MINT-4821299(identity)	-	comment:mint	-	figure legend:F5A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293ft)|taxid:9606(Homo sapiens HEK293FT cell line)	-	2007/07/11	2014/10/16	rogid:4KqD4JrD5D19rKv+pB79yMDjrgU8355	rogid:9sVQXQeFtWj/Vjbc/ABl3kHS5dE8355	intact-crc:94FF0CE62A687FFF|rigid:gkFUHKN8F8amgKoagoYndSiRao8	false	ha tag:?-?(MINT-4821294)	green fluorescent protein tag:?-?(MINT-4821300)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:A5J090	uniprotkb:P51142	intact:EBI-7401819|intact:MINT-4821054	intact:EBI-6257503	psi-mi:a5j090_xenla(display_long)	psi-mi:dvl2_xenla(display_long)|uniprotkb:dvl2(gene name)|psi-mi:dvl2(display_short)|uniprotkb:dsh(gene name synonym)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:Xdsh(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kim et al. (2007)	pubmed:17476309|imex:IM-11049|mint:MINT-5219908	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7402195|mint:MINT-4821333|imex:IM-11049-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR014752(Arrestin, C-terminal)|mint:A5J090|interpro:IPR017864|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR000698(Arrestin)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR014753(Arrestin, N-terminal)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|mint:MINT-4821334(identity)	go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0022008"(neurogenesis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045545"(syndecan binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0060026"(convergent extension)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060271"(cilium assembly)|go:"GO:0090630"(activation of GTPase activity)|rcsb pdb:1L6O|rcsb pdb:2F0A|rcsb pdb:3FY5|mint:P51142|refseq:NP_001084096.1|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR024580|interpro:IPR003351(Dishevelled protein)|interpro:IPR001158(DIX)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR029071|interpro:IPR038207|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|mint:MINT-4821340(identity)	-	comment:mint	-	figure legend:F6K|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293ft)|taxid:9606(Homo sapiens HEK293FT cell line)	-	2007/07/11	2014/10/16	rogid:4KqD4JrD5D19rKv+pB79yMDjrgU8355	rogid:9sVQXQeFtWj/Vjbc/ABl3kHS5dE8355	intact-crc:850E74A4BDCF051D|rigid:gkFUHKN8F8amgKoagoYndSiRao8	false	green fluorescent protein tag:?-?(MINT-4821335)	myc tag:?-?(MINT-4821344)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:A5J090	uniprotkb:P51142	intact:EBI-7401819|intact:MINT-4821054	intact:EBI-6257503	psi-mi:a5j090_xenla(display_long)	psi-mi:dvl2_xenla(display_long)|uniprotkb:dvl2(gene name)|psi-mi:dvl2(display_short)|uniprotkb:dsh(gene name synonym)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:Xdsh(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kim et al. (2007)	pubmed:17476309|imex:IM-11049|mint:MINT-5219908	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7402170|mint:MINT-4821307|imex:IM-11049-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR014752(Arrestin, C-terminal)|mint:A5J090|interpro:IPR017864|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR000698(Arrestin)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR014753(Arrestin, N-terminal)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|mint:MINT-4821314(identity)	go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0022008"(neurogenesis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045545"(syndecan binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0060026"(convergent extension)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060271"(cilium assembly)|go:"GO:0090630"(activation of GTPase activity)|rcsb pdb:1L6O|rcsb pdb:2F0A|rcsb pdb:3FY5|mint:P51142|refseq:NP_001084096.1|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR024580|interpro:IPR003351(Dishevelled protein)|interpro:IPR001158(DIX)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR029071|interpro:IPR038207|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|mint:MINT-4821308(identity)	-	comment:mint	-	figure legend:F5B|figure legend:F5C|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293ft)|taxid:9606(Homo sapiens HEK293FT cell line)	-	2007/07/11	2014/10/16	rogid:4KqD4JrD5D19rKv+pB79yMDjrgU8355	rogid:9sVQXQeFtWj/Vjbc/ABl3kHS5dE8355	intact-crc:11086FF997A91600|rigid:gkFUHKN8F8amgKoagoYndSiRao8	false	green fluorescent protein tag:?-?(MINT-4821317)	binding-associated region:1-82(MINT-4821329)|ha tag:?-?(MINT-4821309)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P51142	uniprotkb:Q9Y4D1	intact:EBI-6257503	intact:EBI-2817289|uniprotkb:Q8N1Z8|uniprotkb:Q86U34|uniprotkb:Q8TB39|ensembl:ENSP00000378557	psi-mi:dvl2_xenla(display_long)|uniprotkb:dvl2(gene name)|psi-mi:dvl2(display_short)|uniprotkb:dsh(gene name synonym)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:Xdsh(gene name synonym)	psi-mi:daam1_human(display_long)|uniprotkb:DAAM1(gene name)|psi-mi:DAAM1(display_short)|uniprotkb:KIAA0666(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kim et al. (2007)	pubmed:17476309|imex:IM-11049|mint:MINT-5219908	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7402231|mint:MINT-4821379|imex:IM-11049-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0022008"(neurogenesis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045545"(syndecan binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0060026"(convergent extension)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060271"(cilium assembly)|go:"GO:0090630"(activation of GTPase activity)|rcsb pdb:1L6O|rcsb pdb:2F0A|rcsb pdb:3FY5|mint:P51142|refseq:NP_001084096.1|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR024580|interpro:IPR003351(Dishevelled protein)|interpro:IPR001158(DIX)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR029071|interpro:IPR038207|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|mint:MINT-4821386(identity)	refseq:XP_005267487.1|refseq:NP_055807.1|refseq:NP_001257449.1|refseq:XP_005267488.1|ensembl:ENSG00000100592(gene)|ensembl:ENST00000395125(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031514"(motile cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|mint:Q9Y4D1|rcsb pdb:2J1D|rcsb pdb:2Z6E|reactome:R-HSA-4086400|reactome:R-HSA-5663220|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|interpro:IPR014767(Diaphanous autoregulatory)|dip:DIP-29641N|mint:MINT-4821380(identity)	-	-	-	figure legend:F6K|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293ft)|taxid:9606(Homo sapiens HEK293FT cell line)	-	2007/07/11	2014/10/16	rogid:9sVQXQeFtWj/Vjbc/ABl3kHS5dE8355	rogid:nAvD3Yprt2Ayj2wLfyI15HIoyLI9606	intact-crc:576B925FBBF983E3|rigid:1TmvVe5mmOUJXm7d+6yWuvGdZ3s	false	myc tag:?-?(MINT-4821387)	ha tag:?-?(MINT-4821383)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:A5J090	uniprotkb:Q9Y4D1	intact:EBI-7401819|intact:MINT-4821054	intact:EBI-2817289|uniprotkb:Q8N1Z8|uniprotkb:Q86U34|uniprotkb:Q8TB39|ensembl:ENSP00000378557	psi-mi:a5j090_xenla(display_long)	psi-mi:daam1_human(display_long)|uniprotkb:DAAM1(gene name)|psi-mi:DAAM1(display_short)|uniprotkb:KIAA0666(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kim et al. (2007)	pubmed:17476309|imex:IM-11049|mint:MINT-5219908	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7402213|mint:MINT-4821359|imex:IM-11049-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR014752(Arrestin, C-terminal)|mint:A5J090|interpro:IPR017864|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR000698(Arrestin)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR014753(Arrestin, N-terminal)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|mint:MINT-4821360(identity)	refseq:XP_005267487.1|refseq:NP_055807.1|refseq:NP_001257449.1|refseq:XP_005267488.1|ensembl:ENSG00000100592(gene)|ensembl:ENST00000395125(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031514"(motile cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|mint:Q9Y4D1|rcsb pdb:2J1D|rcsb pdb:2Z6E|reactome:R-HSA-4086400|reactome:R-HSA-5663220|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|interpro:IPR014767(Diaphanous autoregulatory)|dip:DIP-29641N|mint:MINT-4821366(identity)	-	comment:mint	-	figure legend:F6A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293ft)|taxid:9606(Homo sapiens HEK293FT cell line)	-	2007/07/11	2014/10/16	rogid:4KqD4JrD5D19rKv+pB79yMDjrgU8355	rogid:nAvD3Yprt2Ayj2wLfyI15HIoyLI9606	intact-crc:F8F49A753AD4D569|rigid:5Ky7AvX85WtAuV4paPFy3MknUoc	false	green fluorescent protein tag:?-?(MINT-4821363)	ha tag:?-?(MINT-4821367)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:A5J090	uniprotkb:Q9W760	intact:EBI-7401819|intact:MINT-4821054	intact:EBI-7401858|intact:MINT-4821165	psi-mi:a5j090_xenla(display_long)	psi-mi:q9w760_xenla(display_long)|uniprotkb:RhoA(gene name)|psi-mi:RhoA(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kim et al. (2007)	pubmed:17476309|imex:IM-11049|mint:MINT-5219908	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7402272|mint:MINT-4821398|imex:IM-11049-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR014752(Arrestin, C-terminal)|mint:A5J090|interpro:IPR017864|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR000698(Arrestin)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR014753(Arrestin, N-terminal)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|mint:MINT-4821405(identity)	mint:Q9W760|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR027417|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:1902766"(skeletal muscle satellite cell migration)|mint:MINT-4821399(identity)	-	comment:mint	comment:mint	figure legend:F7A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293ft)|taxid:9606(Homo sapiens HEK293FT cell line)	-	2007/07/11	2014/10/16	rogid:4KqD4JrD5D19rKv+pB79yMDjrgU8355	rogid:/P4iF74RDAqjT7Y5CRCYxwThZtA8355	intact-crc:4BF816C09138719B|rigid:wBos6DaC0cf8SxWW8YSqRzDT4Gg	false	green fluorescent protein tag:?-?(MINT-4821408)	myc tag:?-?(MINT-4821400)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P60022	uniprotkb:Q9W760	intact:EBI-7200390|ensembl:ENSP00000297439|ensembl:ENSP00000494448|intact:MINT-5306206|uniprotkb:Q09753	intact:EBI-7401858|intact:MINT-4821165	psi-mi:defb1_human(display_long)|uniprotkb:Defensin, beta 1(gene name synonym)|uniprotkb:DEFB1(gene name)|psi-mi:DEFB1(display_short)|uniprotkb:BD1(gene name synonym)|uniprotkb:HBD1(gene name synonym)	psi-mi:q9w760_xenla(display_long)|uniprotkb:RhoA(gene name)|psi-mi:RhoA(display_short)	psi-mi:"MI:0096"(pull down)	Kim et al. (2007)	pubmed:17476309|imex:IM-11049|mint:MINT-5219908	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7402320|mint:MINT-4821148|imex:IM-11049-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031731"(CCR6 chemokine receptor binding)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0060474"(positive regulation of flagellated sperm motility involved in capacitation)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097225"(sperm midpiece)|go:"GO:1990742"(microvesicle)|interpro:IPR001855(Beta defensin)|mint:P60022|rcsb pdb:1E4S|rcsb pdb:1IJU|rcsb pdb:1IJV|rcsb pdb:1KJ5|rcsb pdb:2NLB|rcsb pdb:2NLC|rcsb pdb:2NLD|rcsb pdb:2NLE|rcsb pdb:2NLF|rcsb pdb:2NLG|rcsb pdb:2NLH|rcsb pdb:2NLP|rcsb pdb:2NLQ|rcsb pdb:2NLS|rcsb pdb:2PLZ|reactome:R-HSA-1461957|reactome:R-HSA-1461973|ensembl:ENSG00000164825(gene)|ensembl:ENSG00000284881(gene)|ensembl:ENST00000297439(transcript)|ensembl:ENST00000642865(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005796"(Golgi lumen)|go:"GO:0006935"(chemotaxis)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0009617"(response to bacterium)|go:"GO:0019731"(antibacterial humoral response)|refseq:NP_005209.1|mint:MINT-4821149(identity)	mint:Q9W760|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR027417|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:1902766"(skeletal muscle satellite cell migration)|mint:MINT-4821155(identity)	-	comment:mint|function:Has bactericidal activity|comment:homomint	comment:mint	figure legend:F3F|figure legend:F4I|comment:Overexpression of Xbarr2 increases this interaction.|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/07/11	2014/10/16	rogid:Id6WT3vWjsgpsC93JiiUNrC8x+89606	rogid:/P4iF74RDAqjT7Y5CRCYxwThZtA8355	intact-crc:67D8FEFECB00F1CE|rigid:oXcYaTrL3OUNUawYAbKgsmIyMcI	false	glutathione s tranferase tag:?-?(MINT-4821150)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)