#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P48582	uniprotkb:P32571	intact:EBI-3768|uniprotkb:Q02823|uniprotkb:D6W3T3|ensemblfungi:YPL084W	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	psi-mi:bro1_yeast(display_long)|uniprotkb:ASI6(gene name synonym)|uniprotkb:NPI3(gene name synonym)|uniprotkb:VPS31(gene name synonym)|uniprotkb:YPL084W(locus name)|uniprotkb:BRO1(gene name)|psi-mi:BRO1(display_short)|uniprotkb:LPF2(gene name synonym)|uniprotkb:BRO domain-containing protein 1(gene name synonym)|uniprotkb:BCK1-like resistance to osmotic shock protein 1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 31(gene name synonym)|uniprotkb:Amino acid sensor-independent protein 6(gene name synonym)|uniprotkb:Nitrogen permease inactivating protein 3(gene name synonym)	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Richter et al. (2007)	pubmed:17446860|imex:IM-11278|mint:MINT-5219867	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7382279|mint:MINT-4793878|imex:IM-11278-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015241.1|sgd:S000006005|dip:DIP-2225N|mint:P48582|ensemblfungi:YPL084W(gene)|ensemblfungi:YPL084W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0010008"(endosome membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904669"(ATP export)|go:"GO:2000158"(positive regulation of ubiquitin-specific protease activity)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|rcsb pdb:1ZB1|mint:MINT-4793889(identity)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|mint:MINT-4793880(identity)	-	-	-	figure legend:F1E|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/07/02	2014/10/16	rogid:NjHfsUkXCOMX/hs2rxrzuXSSe3Q559292	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	intact-crc:7B9EA479DA18443B|rigid:wlkRGpk1e1Mtkdsjm/4vPW1W4fY	false	-	binding-associated region:1-560(MINT-4793881)|ha tag:?-?(MINT-4793885)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32571	uniprotkb:P48582	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	intact:EBI-3768|uniprotkb:Q02823|uniprotkb:D6W3T3|ensemblfungi:YPL084W	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:bro1_yeast(display_long)|uniprotkb:ASI6(gene name synonym)|uniprotkb:NPI3(gene name synonym)|uniprotkb:VPS31(gene name synonym)|uniprotkb:YPL084W(locus name)|uniprotkb:BRO1(gene name)|psi-mi:BRO1(display_short)|uniprotkb:LPF2(gene name synonym)|uniprotkb:BRO domain-containing protein 1(gene name synonym)|uniprotkb:BCK1-like resistance to osmotic shock protein 1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 31(gene name synonym)|uniprotkb:Amino acid sensor-independent protein 6(gene name synonym)|uniprotkb:Nitrogen permease inactivating protein 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Richter et al. (2007)	pubmed:17446860|imex:IM-11278|mint:MINT-5219867	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7382308|mint:MINT-4793898|imex:IM-11278-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|mint:MINT-4793899(identity)	refseq:NP_015241.1|sgd:S000006005|dip:DIP-2225N|mint:P48582|ensemblfungi:YPL084W(gene)|ensemblfungi:YPL084W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0010008"(endosome membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904669"(ATP export)|go:"GO:2000158"(positive regulation of ubiquitin-specific protease activity)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|rcsb pdb:1ZB1|mint:MINT-4793907(identity)	-	-	-	figure legend:F4C|figure legend:F4B|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/07/02	2014/10/16	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	rogid:NjHfsUkXCOMX/hs2rxrzuXSSe3Q559292	intact-crc:CFCB34D717343B46|rigid:wlkRGpk1e1Mtkdsjm/4vPW1W4fY	false	mutation decreasing interaction:825-825(MINT-4793918)|binding-associated region:560-926(MINT-4793904)|tag:?-?(MINT-4793900)	tag:?-?(MINT-4794078)|binding-associated region:793-844(MINT-4794028)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32571	uniprotkb:P48582	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	intact:EBI-3768|uniprotkb:Q02823|uniprotkb:D6W3T3|ensemblfungi:YPL084W	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:bro1_yeast(display_long)|uniprotkb:ASI6(gene name synonym)|uniprotkb:NPI3(gene name synonym)|uniprotkb:VPS31(gene name synonym)|uniprotkb:YPL084W(locus name)|uniprotkb:BRO1(gene name)|psi-mi:BRO1(display_short)|uniprotkb:LPF2(gene name synonym)|uniprotkb:BRO domain-containing protein 1(gene name synonym)|uniprotkb:BCK1-like resistance to osmotic shock protein 1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 31(gene name synonym)|uniprotkb:Amino acid sensor-independent protein 6(gene name synonym)|uniprotkb:Nitrogen permease inactivating protein 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Richter et al. (2007)	pubmed:17446860|imex:IM-11278|mint:MINT-5219867	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7382407|mint:MINT-4793941|imex:IM-11278-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|mint:MINT-4793946(identity)	refseq:NP_015241.1|sgd:S000006005|dip:DIP-2225N|mint:P48582|ensemblfungi:YPL084W(gene)|ensemblfungi:YPL084W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0010008"(endosome membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904669"(ATP export)|go:"GO:2000158"(positive regulation of ubiquitin-specific protease activity)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|rcsb pdb:1ZB1|mint:MINT-4793942(identity)	-	-	-	figure legend:F4C|figure legend:F4B|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/07/02	2014/10/16	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	rogid:NjHfsUkXCOMX/hs2rxrzuXSSe3Q559292	intact-crc:31FBF6AEB59E731E|rigid:wlkRGpk1e1Mtkdsjm/4vPW1W4fY	false	binding-associated region:560-926(MINT-4793952)|mutation disrupting interaction:826-826(MINT-4793947)|tag:?-?(MINT-4793954)	tag:?-?(MINT-4794072)|binding-associated region:793-844(MINT-4794022)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48582	uniprotkb:P32571	intact:EBI-3768|uniprotkb:Q02823|uniprotkb:D6W3T3|ensemblfungi:YPL084W	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	psi-mi:bro1_yeast(display_long)|uniprotkb:ASI6(gene name synonym)|uniprotkb:NPI3(gene name synonym)|uniprotkb:VPS31(gene name synonym)|uniprotkb:YPL084W(locus name)|uniprotkb:BRO1(gene name)|psi-mi:BRO1(display_short)|uniprotkb:LPF2(gene name synonym)|uniprotkb:BRO domain-containing protein 1(gene name synonym)|uniprotkb:BCK1-like resistance to osmotic shock protein 1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 31(gene name synonym)|uniprotkb:Amino acid sensor-independent protein 6(gene name synonym)|uniprotkb:Nitrogen permease inactivating protein 3(gene name synonym)	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Richter et al. (2007)	pubmed:17446860|imex:IM-11278|mint:MINT-5219867	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7382355|mint:MINT-4793922|imex:IM-11278-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015241.1|sgd:S000006005|dip:DIP-2225N|mint:P48582|ensemblfungi:YPL084W(gene)|ensemblfungi:YPL084W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0010008"(endosome membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904669"(ATP export)|go:"GO:2000158"(positive regulation of ubiquitin-specific protease activity)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|rcsb pdb:1ZB1|mint:MINT-4793934(identity)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|mint:MINT-4793923(identity)	-	-	-	figure legend:F4C|figure legend:F4B|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/07/02	2014/10/16	rogid:NjHfsUkXCOMX/hs2rxrzuXSSe3Q559292	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	intact-crc:4D20FF3FBC0E9150|rigid:wlkRGpk1e1Mtkdsjm/4vPW1W4fY	false	binding-associated region:793-844(MINT-4794025)|tag:?-?(MINT-4794075)	tag:?-?(MINT-4793927)|binding-associated region:560-926(MINT-4793929)|mutation disrupting interaction:824-824(MINT-4793924)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32571	uniprotkb:P48582	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	intact:EBI-3768|uniprotkb:Q02823|uniprotkb:D6W3T3|ensemblfungi:YPL084W	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:bro1_yeast(display_long)|uniprotkb:ASI6(gene name synonym)|uniprotkb:NPI3(gene name synonym)|uniprotkb:VPS31(gene name synonym)|uniprotkb:YPL084W(locus name)|uniprotkb:BRO1(gene name)|psi-mi:BRO1(display_short)|uniprotkb:LPF2(gene name synonym)|uniprotkb:BRO domain-containing protein 1(gene name synonym)|uniprotkb:BCK1-like resistance to osmotic shock protein 1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 31(gene name synonym)|uniprotkb:Amino acid sensor-independent protein 6(gene name synonym)|uniprotkb:Nitrogen permease inactivating protein 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Richter et al. (2007)	pubmed:17446860|imex:IM-11278|mint:MINT-5219867	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7382439|mint:MINT-4793959|imex:IM-11278-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|mint:MINT-4793960(identity)	refseq:NP_015241.1|sgd:S000006005|dip:DIP-2225N|mint:P48582|ensemblfungi:YPL084W(gene)|ensemblfungi:YPL084W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0010008"(endosome membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904669"(ATP export)|go:"GO:2000158"(positive regulation of ubiquitin-specific protease activity)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|rcsb pdb:1ZB1|mint:MINT-4793971(identity)	-	-	-	figure legend:F4C|figure legend:F4B|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/07/02	2014/10/16	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	rogid:NjHfsUkXCOMX/hs2rxrzuXSSe3Q559292	intact-crc:0F96726631560239|rigid:wlkRGpk1e1Mtkdsjm/4vPW1W4fY	false	binding-associated region:560-926(MINT-4793963)|tag:?-?(MINT-4793961)|mutation disrupting interaction:827-827(MINT-4793967)	tag:?-?(MINT-4794069)|binding-associated region:793-844(MINT-4794019)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32571	uniprotkb:P48582	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	intact:EBI-3768|uniprotkb:Q02823|uniprotkb:D6W3T3|ensemblfungi:YPL084W	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:bro1_yeast(display_long)|uniprotkb:ASI6(gene name synonym)|uniprotkb:NPI3(gene name synonym)|uniprotkb:VPS31(gene name synonym)|uniprotkb:YPL084W(locus name)|uniprotkb:BRO1(gene name)|psi-mi:BRO1(display_short)|uniprotkb:LPF2(gene name synonym)|uniprotkb:BRO domain-containing protein 1(gene name synonym)|uniprotkb:BCK1-like resistance to osmotic shock protein 1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 31(gene name synonym)|uniprotkb:Amino acid sensor-independent protein 6(gene name synonym)|uniprotkb:Nitrogen permease inactivating protein 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Richter et al. (2007)	pubmed:17446860|imex:IM-11278|mint:MINT-5219867	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7382471|mint:MINT-4793977|imex:IM-11278-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|mint:MINT-4793982(identity)	refseq:NP_015241.1|sgd:S000006005|dip:DIP-2225N|mint:P48582|ensemblfungi:YPL084W(gene)|ensemblfungi:YPL084W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0010008"(endosome membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904669"(ATP export)|go:"GO:2000158"(positive regulation of ubiquitin-specific protease activity)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|rcsb pdb:1ZB1|mint:MINT-4793978(identity)	-	-	-	figure legend:F4C|figure legend:F4B|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/07/02	2014/10/16	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	rogid:NjHfsUkXCOMX/hs2rxrzuXSSe3Q559292	intact-crc:C9974E910DA4ADD2|rigid:wlkRGpk1e1Mtkdsjm/4vPW1W4fY	false	mutation disrupting interaction:829-829(MINT-4793983)|binding-associated region:560-926(MINT-4793988)|tag:?-?(MINT-4793990)	tag:?-?(MINT-4794066)|binding-associated region:793-844(MINT-4794016)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32571	uniprotkb:P48582	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	intact:EBI-3768|uniprotkb:Q02823|uniprotkb:D6W3T3|ensemblfungi:YPL084W	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:bro1_yeast(display_long)|uniprotkb:ASI6(gene name synonym)|uniprotkb:NPI3(gene name synonym)|uniprotkb:VPS31(gene name synonym)|uniprotkb:YPL084W(locus name)|uniprotkb:BRO1(gene name)|psi-mi:BRO1(display_short)|uniprotkb:LPF2(gene name synonym)|uniprotkb:BRO domain-containing protein 1(gene name synonym)|uniprotkb:BCK1-like resistance to osmotic shock protein 1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 31(gene name synonym)|uniprotkb:Amino acid sensor-independent protein 6(gene name synonym)|uniprotkb:Nitrogen permease inactivating protein 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Richter et al. (2007)	pubmed:17446860|imex:IM-11278|mint:MINT-5219867	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7382542|mint:MINT-4793995|imex:IM-11278-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|mint:MINT-4793996(identity)	refseq:NP_015241.1|sgd:S000006005|dip:DIP-2225N|mint:P48582|ensemblfungi:YPL084W(gene)|ensemblfungi:YPL084W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0010008"(endosome membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904669"(ATP export)|go:"GO:2000158"(positive regulation of ubiquitin-specific protease activity)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|rcsb pdb:1ZB1|mint:MINT-4794007(identity)	-	-	-	figure legend:F4C|figure legend:F4B|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/07/02	2014/10/16	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	rogid:NjHfsUkXCOMX/hs2rxrzuXSSe3Q559292	intact-crc:4B9B1E09C4BC8093|rigid:wlkRGpk1e1Mtkdsjm/4vPW1W4fY	false	tag:?-?(MINT-4793997)|mutation disrupting interaction:830-830(MINT-4794003)|binding-associated region:560-926(MINT-4793999)	binding-associated region:793-844(MINT-4794013)|tag:?-?(MINT-4794062)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32571	uniprotkb:P48582	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	intact:EBI-3768|uniprotkb:Q02823|uniprotkb:D6W3T3|ensemblfungi:YPL084W	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:bro1_yeast(display_long)|uniprotkb:ASI6(gene name synonym)|uniprotkb:NPI3(gene name synonym)|uniprotkb:VPS31(gene name synonym)|uniprotkb:YPL084W(locus name)|uniprotkb:BRO1(gene name)|psi-mi:BRO1(display_short)|uniprotkb:LPF2(gene name synonym)|uniprotkb:BRO domain-containing protein 1(gene name synonym)|uniprotkb:BCK1-like resistance to osmotic shock protein 1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 31(gene name synonym)|uniprotkb:Amino acid sensor-independent protein 6(gene name synonym)|uniprotkb:Nitrogen permease inactivating protein 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Richter et al. (2007)	pubmed:17446860|imex:IM-11278|mint:MINT-5219867	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7382612|mint:MINT-4794082|imex:IM-11278-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|mint:MINT-4794094(identity)	refseq:NP_015241.1|sgd:S000006005|dip:DIP-2225N|mint:P48582|ensemblfungi:YPL084W(gene)|ensemblfungi:YPL084W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0010008"(endosome membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904669"(ATP export)|go:"GO:2000158"(positive regulation of ubiquitin-specific protease activity)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|rcsb pdb:1ZB1|mint:MINT-4794083(identity)	-	-	-	figure legend:F6B|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/07/02	2014/10/16	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	rogid:NjHfsUkXCOMX/hs2rxrzuXSSe3Q559292	intact-crc:96F730BCFC9C333A|rigid:wlkRGpk1e1Mtkdsjm/4vPW1W4fY	false	binding-associated region:560-926(MINT-4794097)|tag:?-?(MINT-4794095)	tag:?-?(MINT-4794085)|binding-associated region:793-844(MINT-4794091)|mutation disrupting interaction:831-831(MINT-4794087)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32571	uniprotkb:P48582	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	intact:EBI-3768|uniprotkb:Q02823|uniprotkb:D6W3T3|ensemblfungi:YPL084W	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:bro1_yeast(display_long)|uniprotkb:ASI6(gene name synonym)|uniprotkb:NPI3(gene name synonym)|uniprotkb:VPS31(gene name synonym)|uniprotkb:YPL084W(locus name)|uniprotkb:BRO1(gene name)|psi-mi:BRO1(display_short)|uniprotkb:LPF2(gene name synonym)|uniprotkb:BRO domain-containing protein 1(gene name synonym)|uniprotkb:BCK1-like resistance to osmotic shock protein 1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 31(gene name synonym)|uniprotkb:Amino acid sensor-independent protein 6(gene name synonym)|uniprotkb:Nitrogen permease inactivating protein 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Richter et al. (2007)	pubmed:17446860|imex:IM-11278|mint:MINT-5219867	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7382574|mint:MINT-4794031|imex:IM-11278-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|mint:MINT-4794038(identity)	refseq:NP_015241.1|sgd:S000006005|dip:DIP-2225N|mint:P48582|ensemblfungi:YPL084W(gene)|ensemblfungi:YPL084W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0010008"(endosome membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904669"(ATP export)|go:"GO:2000158"(positive regulation of ubiquitin-specific protease activity)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|rcsb pdb:1ZB1|mint:MINT-4794032(identity)	-	-	-	figure legend:F6B|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/07/02	2014/10/16	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	rogid:NjHfsUkXCOMX/hs2rxrzuXSSe3Q559292	intact-crc:18C5FD5B8875314E|rigid:wlkRGpk1e1Mtkdsjm/4vPW1W4fY	false	binding-associated region:560-926(MINT-4794044)|tag:?-?(MINT-4794046)	binding-associated region:793-844(MINT-4794033)|tag:?-?(MINT-4794058)|mutation disrupting interaction:831-834(MINT-4794054)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32571	uniprotkb:P48582	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	intact:EBI-3768|uniprotkb:Q02823|uniprotkb:D6W3T3|ensemblfungi:YPL084W	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:bro1_yeast(display_long)|uniprotkb:ASI6(gene name synonym)|uniprotkb:NPI3(gene name synonym)|uniprotkb:VPS31(gene name synonym)|uniprotkb:YPL084W(locus name)|uniprotkb:BRO1(gene name)|psi-mi:BRO1(display_short)|uniprotkb:LPF2(gene name synonym)|uniprotkb:BRO domain-containing protein 1(gene name synonym)|uniprotkb:BCK1-like resistance to osmotic shock protein 1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 31(gene name synonym)|uniprotkb:Amino acid sensor-independent protein 6(gene name synonym)|uniprotkb:Nitrogen permease inactivating protein 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Richter et al. (2007)	pubmed:17446860|imex:IM-11278|mint:MINT-5219867	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7382710|mint:MINT-4794104|imex:IM-11278-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|mint:MINT-4794105(identity)	refseq:NP_015241.1|sgd:S000006005|dip:DIP-2225N|mint:P48582|ensemblfungi:YPL084W(gene)|ensemblfungi:YPL084W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0010008"(endosome membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904669"(ATP export)|go:"GO:2000158"(positive regulation of ubiquitin-specific protease activity)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|rcsb pdb:1ZB1|mint:MINT-4794113(identity)	-	-	-	figure legend:F6B|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/07/02	2014/10/16	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	rogid:NjHfsUkXCOMX/hs2rxrzuXSSe3Q559292	intact-crc:2AF9E3B2EF5201C6|rigid:wlkRGpk1e1Mtkdsjm/4vPW1W4fY	false	tag:?-?(MINT-4794110)|binding-associated region:560-926(MINT-4794108)	tag:?-?(MINT-4794120)|binding-associated region:793-844(MINT-4794117)|mutation disrupting interaction:832-832(MINT-4794114)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48582	uniprotkb:P32571	intact:EBI-3768|uniprotkb:Q02823|uniprotkb:D6W3T3|ensemblfungi:YPL084W	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	psi-mi:bro1_yeast(display_long)|uniprotkb:ASI6(gene name synonym)|uniprotkb:NPI3(gene name synonym)|uniprotkb:VPS31(gene name synonym)|uniprotkb:YPL084W(locus name)|uniprotkb:BRO1(gene name)|psi-mi:BRO1(display_short)|uniprotkb:LPF2(gene name synonym)|uniprotkb:BRO domain-containing protein 1(gene name synonym)|uniprotkb:BCK1-like resistance to osmotic shock protein 1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 31(gene name synonym)|uniprotkb:Amino acid sensor-independent protein 6(gene name synonym)|uniprotkb:Nitrogen permease inactivating protein 3(gene name synonym)	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Richter et al. (2007)	pubmed:17446860|imex:IM-11278|mint:MINT-5219867	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7382741|mint:MINT-4794126|imex:IM-11278-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015241.1|sgd:S000006005|dip:DIP-2225N|mint:P48582|ensemblfungi:YPL084W(gene)|ensemblfungi:YPL084W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0010008"(endosome membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904669"(ATP export)|go:"GO:2000158"(positive regulation of ubiquitin-specific protease activity)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|rcsb pdb:1ZB1|mint:MINT-4794127(identity)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|mint:MINT-4794138(identity)	-	-	-	figure legend:F6B|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/07/02	2014/10/16	rogid:NjHfsUkXCOMX/hs2rxrzuXSSe3Q559292	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	intact-crc:D103AD48E1E8106D|rigid:wlkRGpk1e1Mtkdsjm/4vPW1W4fY	false	tag:?-?(MINT-4794129)|binding-associated region:793-844(MINT-4794132)|mutation disrupting interaction:833-833(MINT-4794134)	tag:?-?(MINT-4794139)|binding-associated region:560-926(MINT-4794141)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48582	uniprotkb:P32571	intact:EBI-3768|uniprotkb:Q02823|uniprotkb:D6W3T3|ensemblfungi:YPL084W	intact:EBI-19840|uniprotkb:D6VS55|ensemblfungi:YDR069C	psi-mi:bro1_yeast(display_long)|uniprotkb:ASI6(gene name synonym)|uniprotkb:NPI3(gene name synonym)|uniprotkb:VPS31(gene name synonym)|uniprotkb:YPL084W(locus name)|uniprotkb:BRO1(gene name)|psi-mi:BRO1(display_short)|uniprotkb:LPF2(gene name synonym)|uniprotkb:BRO domain-containing protein 1(gene name synonym)|uniprotkb:BCK1-like resistance to osmotic shock protein 1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 31(gene name synonym)|uniprotkb:Amino acid sensor-independent protein 6(gene name synonym)|uniprotkb:Nitrogen permease inactivating protein 3(gene name synonym)	psi-mi:ubp4_yeast(display_long)|uniprotkb:DOA4(gene name)|psi-mi:DOA4(display_short)|uniprotkb:MUT4(gene name synonym)|uniprotkb:SSV7(gene name synonym)|uniprotkb:YDR069C(locus name)|uniprotkb:YD9609.23C(orf name)|uniprotkb:YD8554.02C(orf name)|uniprotkb:D4270(orf name)|uniprotkb:NPI2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 4(gene name synonym)|uniprotkb:Deubiquitinating enzyme 4(gene name synonym)|uniprotkb:Vacuole biogenesis protein SSV7(gene name synonym)|uniprotkb:Ubiquitin thioesterase 4(gene name synonym)|uniprotkb:DOS1(gene name synonym)|uniprotkb:UBP4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Richter et al. (2007)	pubmed:17446860|imex:IM-11278|mint:MINT-5219867	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7382787|mint:MINT-4794148|imex:IM-11278-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015241.1|sgd:S000006005|dip:DIP-2225N|mint:P48582|ensemblfungi:YPL084W(gene)|ensemblfungi:YPL084W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0010008"(endosome membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904669"(ATP export)|go:"GO:2000158"(positive regulation of ubiquitin-specific protease activity)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|rcsb pdb:1ZB1|mint:MINT-4794157(identity)	sgd:S000002476|ensemblfungi:YDR069C(gene)|ensemblfungi:YDR069C_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0010995"(free ubiquitin chain depolymerization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1904669"(ATP export)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|refseq:NP_010354.3|dip:DIP-5298N|mint:P32571|mint:MINT-4794149(identity)	-	-	-	figure legend:F6B|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/07/02	2014/10/16	rogid:NjHfsUkXCOMX/hs2rxrzuXSSe3Q559292	rogid:UTBSWmpygyxo1ygxp/sQ8wgqnMo559292	intact-crc:E2E445AEC8CE643F|rigid:wlkRGpk1e1Mtkdsjm/4vPW1W4fY	false	tag:?-?(MINT-4794164)|mutation disrupting interaction:834-834(MINT-4794158)|binding-associated region:793-844(MINT-4794161)	binding-associated region:560-926(MINT-4794152)|tag:?-?(MINT-4794154)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48582	uniprotkb:P39929	intact:EBI-3768|uniprotkb:Q02823|uniprotkb:D6W3T3|ensemblfungi:YPL084W	intact:EBI-17554|uniprotkb:D6VY27|ensemblfungi:YLR025W|uniprotkb:E9P8V6	psi-mi:bro1_yeast(display_long)|uniprotkb:ASI6(gene name synonym)|uniprotkb:NPI3(gene name synonym)|uniprotkb:VPS31(gene name synonym)|uniprotkb:YPL084W(locus name)|uniprotkb:BRO1(gene name)|psi-mi:BRO1(display_short)|uniprotkb:LPF2(gene name synonym)|uniprotkb:BRO domain-containing protein 1(gene name synonym)|uniprotkb:BCK1-like resistance to osmotic shock protein 1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 31(gene name synonym)|uniprotkb:Amino acid sensor-independent protein 6(gene name synonym)|uniprotkb:Nitrogen permease inactivating protein 3(gene name synonym)	psi-mi:snf7_yeast(display_long)|uniprotkb:SNF7(gene name)|psi-mi:SNF7(display_short)|uniprotkb:VPS32(gene name synonym)|uniprotkb:YLR025W(locus name)|uniprotkb:DID1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 32(gene name synonym)|uniprotkb:DOA4-independent degradation protein 1(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Richter et al. (2007)	pubmed:17446860|imex:IM-11278|mint:MINT-5219867	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7382818|mint:MINT-4794171|imex:IM-11278-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015241.1|sgd:S000006005|dip:DIP-2225N|mint:P48582|ensemblfungi:YPL084W(gene)|ensemblfungi:YPL084W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0010008"(endosome membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904669"(ATP export)|go:"GO:2000158"(positive regulation of ubiquitin-specific protease activity)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|rcsb pdb:1ZB1|mint:MINT-4794172(identity)	refseq:NP_013125.1|sgd:S000004015|ensemblfungi:YLR025W(gene)|ensemblfungi:YLR025W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0071454"(cellular response to anoxia)|go:"GO:1904669"(ATP export)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:5FD7|rcsb pdb:5FD9|rcsb pdb:5T8L|rcsb pdb:5T8N|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1747N|mint:P39929|mint:MINT-4794183(identity)	-	-	crc64:5241A18BB181F0C1	figure legend:F4C|figure legend:F4B|comment:homomint|comment:domino|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/07/02	2014/10/16	rogid:NjHfsUkXCOMX/hs2rxrzuXSSe3Q559292	rogid:I8qBtNlqTjxLX1HginTOzM3o9oA559292	intact-crc:0A14D3625C7AA855|rigid:yPF4WMQBsNz+QbZECddpRWOve1w	false	tag:?-?(MINT-4794174)|binding-associated region:?-?(MINT-4794177)	tag:?-?(MINT-4794184)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39929	uniprotkb:P48582	intact:EBI-17554|uniprotkb:D6VY27|ensemblfungi:YLR025W|uniprotkb:E9P8V6	intact:EBI-3768|uniprotkb:Q02823|uniprotkb:D6W3T3|ensemblfungi:YPL084W	psi-mi:snf7_yeast(display_long)|uniprotkb:SNF7(gene name)|psi-mi:SNF7(display_short)|uniprotkb:VPS32(gene name synonym)|uniprotkb:YLR025W(locus name)|uniprotkb:DID1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 32(gene name synonym)|uniprotkb:DOA4-independent degradation protein 1(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 7(gene name synonym)	psi-mi:bro1_yeast(display_long)|uniprotkb:ASI6(gene name synonym)|uniprotkb:NPI3(gene name synonym)|uniprotkb:VPS31(gene name synonym)|uniprotkb:YPL084W(locus name)|uniprotkb:BRO1(gene name)|psi-mi:BRO1(display_short)|uniprotkb:LPF2(gene name synonym)|uniprotkb:BRO domain-containing protein 1(gene name synonym)|uniprotkb:BCK1-like resistance to osmotic shock protein 1(gene name synonym)|uniprotkb:Vacuolar protein-sorting-associated protein 31(gene name synonym)|uniprotkb:Amino acid sensor-independent protein 6(gene name synonym)|uniprotkb:Nitrogen permease inactivating protein 3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Richter et al. (2007)	pubmed:17446860|imex:IM-11278|mint:MINT-5219867	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7382847|mint:MINT-4794198|imex:IM-11278-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013125.1|sgd:S000004015|ensemblfungi:YLR025W(gene)|ensemblfungi:YLR025W_mRNA(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0071454"(cellular response to anoxia)|go:"GO:1904669"(ATP export)|go:"GO:1904902"(ESCRT III complex assembly)|interpro:IPR005024(Snf7)|rcsb pdb:5FD7|rcsb pdb:5FD9|rcsb pdb:5T8L|rcsb pdb:5T8N|reactome:R-SCE-1632852|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1747N|mint:P39929|mint:MINT-4794199(identity)	refseq:NP_015241.1|sgd:S000006005|dip:DIP-2225N|mint:P48582|ensemblfungi:YPL084W(gene)|ensemblfungi:YPL084W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007584"(response to nutrient)|go:"GO:0010008"(endosome membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904669"(ATP export)|go:"GO:2000158"(positive regulation of ubiquitin-specific protease activity)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|rcsb pdb:1ZB1|mint:MINT-4794205(identity)	-	crc64:5241A18BB181F0C1	-	figure legend:F4C|figure legend:F4B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/07/02	2014/10/16	rogid:I8qBtNlqTjxLX1HginTOzM3o9oA559292	rogid:NjHfsUkXCOMX/hs2rxrzuXSSe3Q559292	intact-crc:AA89CA36114BA5B0|rigid:yPF4WMQBsNz+QbZECddpRWOve1w	false	tag:?-?(MINT-4794202)	binding-associated region:692-844(MINT-4794206)|tag:?-?(MINT-4794210)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0CG63	uniprotkb:P27614	intact:EBI-7000452|ensemblfungi:YLL039C|intact:MINT-545233|uniprotkb:D6VXW7|uniprotkb:P61864|uniprotkb:Q6LA96|uniprotkb:P04838	intact:EBI-4146|uniprotkb:D6VW16|ensemblfungi:YJL172W	psi-mi:ubi4p_yeast(display_long)|uniprotkb:UBI4(gene name)|psi-mi:UBI4(display_short)|uniprotkb:SCD2(gene name synonym)|uniprotkb:YLL039C(locus name)	psi-mi:cbps_yeast(display_long)|uniprotkb:CPS1(gene name)|psi-mi:CPS1(display_short)|uniprotkb:CPS(gene name synonym)|uniprotkb:YJL172W(locus name)|uniprotkb:J0510(orf name)|uniprotkb:YSCS(gene name synonym)|uniprotkb:GLY-X carboxypeptidase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Richter et al. (2007)	pubmed:17446860|imex:IM-11278|mint:MINT-5219867	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7382882|mint:MINT-4794217|imex:IM-11278-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLL039C(gene)|ensemblfungi:YLL039C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:1OTR|rcsb pdb:1Q0W|rcsb pdb:1WR1|rcsb pdb:1ZW7|rcsb pdb:2G3Q|rcsb pdb:2JT4|rcsb pdb:2JWZ|rcsb pdb:2KDI|rcsb pdb:2L00|rcsb pdb:3CMM|rcsb pdb:3L0W|rcsb pdb:3L10|rcsb pdb:3OLM|rcsb pdb:4HCN|rcsb pdb:4NNJ|rcsb pdb:4Q5E|rcsb pdb:4Q5H|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-156827|reactome:R-SCE-174113|reactome:R-SCE-1799339|reactome:R-SCE-532668|reactome:R-SCE-5358346|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-5687128|reactome:R-SCE-5689603|reactome:R-SCE-5689877|reactome:R-SCE-5689880|reactome:R-SCE-5689901|reactome:R-SCE-5696395|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6791226|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-72649|reactome:R-SCE-72689|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72706|reactome:R-SCE-75815|reactome:R-SCE-8854050|reactome:R-SCE-8866652|reactome:R-SCE-8866654|reactome:R-SCE-8948747|reactome:R-SCE-8948751|reactome:R-SCE-901032|reactome:R-SCE-9020702|reactome:R-SCE-9033241|reactome:R-SCE-917729|reactome:R-SCE-9646399|reactome:R-SCE-975956|reactome:R-SCE-975957|reactome:R-SCE-983168|interpro:IPR000626(Ubiquitin)|sgd:S000003962|interpro:IPR019956|interpro:IPR019954|refseq:NP_013061.1|interpro:IPR029071|mint:P0CG63|mint:MINT-4794227(identity)	refseq:NP_012363.1|sgd:S000003708|dip:DIP-5566N|mint:P27614|ensemblfungi:YJL172W(gene)|ensemblfungi:YJL172W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005775"(vacuolar lumen)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR002933(Peptidase M20)|interpro:IPR011650(Peptidase M20, dimerisation)|interpro:IPR017141(Peptidase M20, carboxypeptidase S)|interpro:IPR036264|reactome:R-SCE-9673163|mint:MINT-4794218(identity)	-	function:Protein modifier which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Attachment to proteins as a Lys-48-linked polymer usually leads to their degradation by proteasome. Attachment to proteins as a monomer or as an alternatively linked polymer does not lead to proteasomal degradation and may be required for numerous functions, including maintenance of chromatin structure, regulation of gene expression, stress response, ribosome biogenesis and DNA repair|comment:mint	-	figure legend:F3B|comment:"This interaction occurs only if DoA4 protein is mutated (C571S; AAFA)."|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/07/02	2014/10/16	rogid:+GNv/Jc7C11q8cgu2qZ6YkcsIeI559292	rogid:b8eWN+hS5TuV2xLCqVMbnr1nEq8559292	intact-crc:2509E0DA5674C6F3|rigid:fkbcpMYM6nyGgwpZexJ/RaP7dYs	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)