#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P22469	uniprotkb:P14785	intact:EBI-7376821|uniprotkb:Q9VUP1|uniprotkb:Q4V3M0|intact:MINT-4652172|uniprotkb:A0JQ32|ensemblmetazoa:FBpp0075304	intact:EBI-240333|uniprotkb:Q8IGR7|uniprotkb:Q9VTP6|uniprotkb:Q9VTP7|ensemblmetazoa:FBpp0075807	psi-mi:z600_drome(display_long)|uniprotkb:Z600(gene name)|psi-mi:Z600(display_short)|uniprotkb:Protein Fruhstart(gene name synonym)|uniprotkb:frs(gene name synonym)|uniprotkb:CG17962(orf name)	psi-mi:ccna_drome(display_long)|uniprotkb:CycA(gene name)|psi-mi:CycA(display_short)|uniprotkb:CG5940(orf name)	psi-mi:"MI:0096"(pull down)	Gawliński et al. (2007)	pubmed:17431409|imex:IM-10935|mint:MINT-5219855	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7376815|mint:MINT-4652190|imex:IM-10935-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524083.2|flybase:FBgn0004052|ensemblmetazoa:FBgn0004052(gene)|ensemblmetazoa:FBtr0075549(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030332"(cyclin binding)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0051301"(cell division)|mint:P22469|mint:MINT-4652192(identity)	refseq:NP_524030.2|flybase:FBgn0000404|dip:DIP-22019N|ensemblmetazoa:FBgn0000404(gene)|ensemblmetazoa:FBtr0076075(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0035561"(regulation of chromatin binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045169"(fusome)|go:"GO:0045170"(spectrosome)|go:"GO:0045202"(synapse)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0097124"(cyclin A2-CDK2 complex)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P14785|reactome:R-DME-1538133|reactome:R-DME-174184|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-5689880|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69273|reactome:R-DME-69563|reactome:R-DME-69656|mint:MINT-4652191(identity)	-	comment:mint|function:Not known	-	figure legend:F3A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/14	2014/10/16	rogid:D+QltlrWlC3/1YRYluNLdX9xml07227	rogid:Ym2ygZ2vFqtDFvZiyifYjRJ7K5c7227	intact-crc:AB03BB7706E4011D|rigid:4AMsXHfGu9APXOML/fSIrxZhDbE	false	glutathione s tranferase tag:?-?(MINT-4652196)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22469	uniprotkb:P54733	intact:EBI-7376821|uniprotkb:Q9VUP1|uniprotkb:Q4V3M0|intact:MINT-4652172|uniprotkb:A0JQ32|ensemblmetazoa:FBpp0075304	intact:EBI-203549|intact:EBI-1628120|uniprotkb:Q24479|uniprotkb:Q95RP5|uniprotkb:Q9V3B3|uniprotkb:Q9V456|ensemblmetazoa:FBpp0080331|ensemblmetazoa:FBpp0080332|ensemblmetazoa:FBpp0080333|ensemblmetazoa:FBpp0080334	psi-mi:z600_drome(display_long)|uniprotkb:Z600(gene name)|psi-mi:Z600(display_short)|uniprotkb:Protein Fruhstart(gene name synonym)|uniprotkb:frs(gene name synonym)|uniprotkb:CG17962(orf name)	psi-mi:ccne_drome(display_long)|uniprotkb:CycE(gene name)|psi-mi:CycE(display_short)|uniprotkb:CG3938(orf name)	psi-mi:"MI:0096"(pull down)	Gawliński et al. (2007)	pubmed:17431409|imex:IM-10935|mint:MINT-5219855	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7376892|mint:MINT-4652236|imex:IM-10935-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524083.2|flybase:FBgn0004052|ensemblmetazoa:FBgn0004052(gene)|ensemblmetazoa:FBtr0075549(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030332"(cyclin binding)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0051301"(cell division)|mint:P22469|mint:MINT-4652237(identity)	refseq:NP_476959.1|refseq:NP_476960.1|refseq:NP_723924.1|refseq:NP_723925.1|refseq:NP_723926.1|flybase:FBgn0010382|dip:DIP-18331N|ensemblmetazoa:FBgn0010382(gene)|ensemblmetazoa:FBtr0080773(transcript)|ensemblmetazoa:FBtr0080774(transcript)|ensemblmetazoa:FBtr0080775(transcript)|ensemblmetazoa:FBtr0080776(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007277"(pole cell development)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035736"(cell proliferation involved in compound eye morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048665"(neuron fate specification)|go:"GO:0090210"(regulation of establishment of blood-brain barrier)|go:"GO:0097134"(cyclin E1-CDK2 complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P54733|reactome:R-DME-1538133|reactome:R-DME-187577|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-9706019|mint:MINT-4652242(identity)	-	comment:mint|function:Not known	-	figure legend:F3A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/14	2014/10/16	rogid:D+QltlrWlC3/1YRYluNLdX9xml07227	rogid:AwK/vwBDPgICbmeNxOxrcsj5kiQ7227	intact-crc:AAEBF748CB6B2FBC|rigid:+pddkSaKfLb4RAhSvpjfIkrA+IU	false	glutathione s tranferase tag:?-?(MINT-4652238)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22469	uniprotkb:Q9I7I0	intact:EBI-7376821|uniprotkb:Q9VUP1|uniprotkb:Q4V3M0|intact:MINT-4652172|uniprotkb:A0JQ32|ensemblmetazoa:FBpp0075304	intact:EBI-150964|uniprotkb:O96718|uniprotkb:Q9TYG8|ensemblmetazoa:FBpp0084103|ensemblmetazoa:FBpp0306645	psi-mi:z600_drome(display_long)|uniprotkb:Z600(gene name)|psi-mi:Z600(display_short)|uniprotkb:Protein Fruhstart(gene name synonym)|uniprotkb:frs(gene name synonym)|uniprotkb:CG17962(orf name)	psi-mi:ccnb3_drome(display_long)|uniprotkb:CycB3(gene name)|psi-mi:CycB3(display_short)|uniprotkb:CG5814(orf name)	psi-mi:"MI:0096"(pull down)	Gawliński et al. (2007)	pubmed:17431409|imex:IM-10935|mint:MINT-5219855	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7376877|mint:MINT-4652215|imex:IM-10935-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524083.2|flybase:FBgn0004052|ensemblmetazoa:FBgn0004052(gene)|ensemblmetazoa:FBtr0075549(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030332"(cyclin binding)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0051301"(cell division)|mint:P22469|mint:MINT-4652219(identity)	refseq:NP_651303.2|flybase:FBgn0015625|refseq:NP_001262934.1|dip:DIP-22205N|ensemblmetazoa:FBgn0015625(gene)|ensemblmetazoa:FBtr0084728(transcript)|ensemblmetazoa:FBtr0334578(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0035561"(regulation of chromatin binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR015452(G2/mitotic-specific cyclin B3)|interpro:IPR036915|interpro:IPR039361|mint:Q9I7I0|mint:MINT-4652216(identity)	-	comment:mint|function:Not known	-	figure legend:F3A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/14	2014/10/16	rogid:D+QltlrWlC3/1YRYluNLdX9xml07227	rogid:x00iO2ghcNgpERCKftXiPiDv+Is7227	intact-crc:B4040F65261CEF42|rigid:LTgLrYfe0BVoxtb7uc2RlV/aUkw	false	glutathione s tranferase tag:?-?(MINT-4652220)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22469	uniprotkb:P20439	intact:EBI-7376821|uniprotkb:Q9VUP1|uniprotkb:Q4V3M0|intact:MINT-4652172|uniprotkb:A0JQ32|ensemblmetazoa:FBpp0075304	intact:EBI-190039|uniprotkb:Q0E8Y2|uniprotkb:Q8MME2|uniprotkb:Q9I7V2|uniprotkb:Q9TYH6|uniprotkb:Q9TYH7|uniprotkb:Q9V3F4|ensemblmetazoa:FBpp0071822	psi-mi:z600_drome(display_long)|uniprotkb:Z600(gene name)|psi-mi:Z600(display_short)|uniprotkb:Protein Fruhstart(gene name synonym)|uniprotkb:frs(gene name synonym)|uniprotkb:CG17962(orf name)	psi-mi:ccnb_drome(display_long)|uniprotkb:CycB(gene name)|psi-mi:CycB(display_short)|uniprotkb:CG3510(orf name)	psi-mi:"MI:0096"(pull down)	Gawliński et al. (2007)	pubmed:17431409|imex:IM-10935|mint:MINT-5219855	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7376847|mint:MINT-4652204|imex:IM-10935-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524083.2|flybase:FBgn0004052|ensemblmetazoa:FBgn0004052(gene)|ensemblmetazoa:FBtr0075549(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030332"(cyclin binding)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0051301"(cell division)|mint:P22469|mint:MINT-4652208(identity)	refseq:NP_726245.2|refseq:NP_726244.1|refseq:NP_726246.1|refseq:NP_726247.1|flybase:FBgn0000405|ensemblmetazoa:FBgn0000405(gene)|ensemblmetazoa:FBtr0071911(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0035561"(regulation of chromatin binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0048134"(germ-line cyst formation)|go:"GO:0051233"(spindle midzone)|go:"GO:0061952"(midbody abscission)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P20439|reactome:R-DME-174048|reactome:R-DME-176408|reactome:R-DME-176412|reactome:R-DME-176417|reactome:R-DME-2500257|reactome:R-DME-2565942|reactome:R-DME-2995383|reactome:R-DME-3301854|reactome:R-DME-4419969|reactome:R-DME-6804114|reactome:R-DME-68875|reactome:R-DME-69273|reactome:R-DME-69478|reactome:R-DME-75035|reactome:R-DME-8878166|mint:MINT-4652205(identity)	-	comment:mint|function:Not known	-	figure legend:F3A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/14	2014/10/16	rogid:D+QltlrWlC3/1YRYluNLdX9xml07227	rogid:189MafBrFMpT06ZsFFwvx1UWPHw7227	intact-crc:7435BE54C435D975|rigid:oUCvElHocxtuFNSfEcTPo/+G/pw	false	glutathione s tranferase tag:?-?(MINT-4652210)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22469	uniprotkb:P14785	intact:EBI-7376821|uniprotkb:Q9VUP1|uniprotkb:Q4V3M0|intact:MINT-4652172|uniprotkb:A0JQ32|ensemblmetazoa:FBpp0075304	intact:EBI-240333|uniprotkb:Q8IGR7|uniprotkb:Q9VTP6|uniprotkb:Q9VTP7|ensemblmetazoa:FBpp0075807	psi-mi:z600_drome(display_long)|uniprotkb:Z600(gene name)|psi-mi:Z600(display_short)|uniprotkb:Protein Fruhstart(gene name synonym)|uniprotkb:frs(gene name synonym)|uniprotkb:CG17962(orf name)	psi-mi:ccna_drome(display_long)|uniprotkb:CycA(gene name)|psi-mi:CycA(display_short)|uniprotkb:CG5940(orf name)	psi-mi:"MI:0096"(pull down)	Gawliński et al. (2007)	pubmed:17431409|imex:IM-10935|mint:MINT-5219855	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7376907|mint:MINT-4652564|imex:IM-10935-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524083.2|flybase:FBgn0004052|ensemblmetazoa:FBgn0004052(gene)|ensemblmetazoa:FBtr0075549(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030332"(cyclin binding)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0051301"(cell division)|mint:P22469|mint:MINT-4652568(identity)	refseq:NP_524030.2|flybase:FBgn0000404|dip:DIP-22019N|ensemblmetazoa:FBgn0000404(gene)|ensemblmetazoa:FBtr0076075(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0035561"(regulation of chromatin binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045169"(fusome)|go:"GO:0045170"(spectrosome)|go:"GO:0045202"(synapse)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0097124"(cyclin A2-CDK2 complex)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P14785|reactome:R-DME-1538133|reactome:R-DME-174184|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-5689880|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69273|reactome:R-DME-69563|reactome:R-DME-69656|mint:MINT-4652565(identity)	-	comment:mint|function:Not known	-	figure legend:F4D|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/14	2014/10/16	rogid:D+QltlrWlC3/1YRYluNLdX9xml07227	rogid:Ym2ygZ2vFqtDFvZiyifYjRJ7K5c7227	intact-crc:28661409BFA2C0A8|rigid:4AMsXHfGu9APXOML/fSIrxZhDbE	false	mutation disrupting interaction:88-88(MINT-4652577)|glutathione s tranferase tag:?-?(MINT-4652570)	mutation disrupting interaction:239-239,242-242,235-235(MINT-4652584)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22469	uniprotkb:P54733	intact:EBI-7376821|uniprotkb:Q9VUP1|uniprotkb:Q4V3M0|intact:MINT-4652172|uniprotkb:A0JQ32|ensemblmetazoa:FBpp0075304	intact:EBI-203549|intact:EBI-1628120|uniprotkb:Q24479|uniprotkb:Q95RP5|uniprotkb:Q9V3B3|uniprotkb:Q9V456|ensemblmetazoa:FBpp0080331|ensemblmetazoa:FBpp0080332|ensemblmetazoa:FBpp0080333|ensemblmetazoa:FBpp0080334	psi-mi:z600_drome(display_long)|uniprotkb:Z600(gene name)|psi-mi:Z600(display_short)|uniprotkb:Protein Fruhstart(gene name synonym)|uniprotkb:frs(gene name synonym)|uniprotkb:CG17962(orf name)	psi-mi:ccne_drome(display_long)|uniprotkb:CycE(gene name)|psi-mi:CycE(display_short)|uniprotkb:CG3938(orf name)	psi-mi:"MI:0107"(surface plasmon resonance)	Gawliński et al. (2007)	pubmed:17431409|imex:IM-10935|mint:MINT-5219855	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7376985|mint:MINT-4652247|imex:IM-10935-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524083.2|flybase:FBgn0004052|ensemblmetazoa:FBgn0004052(gene)|ensemblmetazoa:FBtr0075549(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030332"(cyclin binding)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0051301"(cell division)|mint:P22469|mint:MINT-4652251(identity)	refseq:NP_476959.1|refseq:NP_476960.1|refseq:NP_723924.1|refseq:NP_723925.1|refseq:NP_723926.1|flybase:FBgn0010382|dip:DIP-18331N|ensemblmetazoa:FBgn0010382(gene)|ensemblmetazoa:FBtr0080773(transcript)|ensemblmetazoa:FBtr0080774(transcript)|ensemblmetazoa:FBtr0080775(transcript)|ensemblmetazoa:FBtr0080776(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007277"(pole cell development)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035736"(cell proliferation involved in compound eye morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048665"(neuron fate specification)|go:"GO:0090210"(regulation of establishment of blood-brain barrier)|go:"GO:0097134"(cyclin E1-CDK2 complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P54733|reactome:R-DME-1538133|reactome:R-DME-187577|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-9706019|mint:MINT-4652248(identity)	-	comment:mint|function:Not known	-	figure legend:T1|figure legend:F3C|figure legend:SF2B|kinetics:kd 96 nanomolar|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/14	2014/10/16	rogid:D+QltlrWlC3/1YRYluNLdX9xml07227	rogid:AwK/vwBDPgICbmeNxOxrcsj5kiQ7227	intact-crc:6CB7F97C778B7D79|rigid:+pddkSaKfLb4RAhSvpjfIkrA+IU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22469	uniprotkb:P14785	intact:EBI-7376821|uniprotkb:Q9VUP1|uniprotkb:Q4V3M0|intact:MINT-4652172|uniprotkb:A0JQ32|ensemblmetazoa:FBpp0075304	intact:EBI-240333|uniprotkb:Q8IGR7|uniprotkb:Q9VTP6|uniprotkb:Q9VTP7|ensemblmetazoa:FBpp0075807	psi-mi:z600_drome(display_long)|uniprotkb:Z600(gene name)|psi-mi:Z600(display_short)|uniprotkb:Protein Fruhstart(gene name synonym)|uniprotkb:frs(gene name synonym)|uniprotkb:CG17962(orf name)	psi-mi:ccna_drome(display_long)|uniprotkb:CycA(gene name)|psi-mi:CycA(display_short)|uniprotkb:CG5940(orf name)	psi-mi:"MI:0107"(surface plasmon resonance)	Gawliński et al. (2007)	pubmed:17431409|imex:IM-10935|mint:MINT-5219855	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7377000|mint:MINT-4652269|imex:IM-10935-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524083.2|flybase:FBgn0004052|ensemblmetazoa:FBgn0004052(gene)|ensemblmetazoa:FBtr0075549(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030332"(cyclin binding)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0051301"(cell division)|mint:P22469|mint:MINT-4652270(identity)	refseq:NP_524030.2|flybase:FBgn0000404|dip:DIP-22019N|ensemblmetazoa:FBgn0000404(gene)|ensemblmetazoa:FBtr0076075(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0035561"(regulation of chromatin binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045169"(fusome)|go:"GO:0045170"(spectrosome)|go:"GO:0045202"(synapse)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0097124"(cyclin A2-CDK2 complex)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P14785|reactome:R-DME-1538133|reactome:R-DME-174184|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-5689880|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69273|reactome:R-DME-69563|reactome:R-DME-69656|mint:MINT-4652273(identity)	-	comment:mint|function:Not known	-	figure legend:T1|figure legend:F3C|figure legend:SF2A|kinetics:kd 38 nanomolar|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/14	2014/10/16	rogid:D+QltlrWlC3/1YRYluNLdX9xml07227	rogid:Ym2ygZ2vFqtDFvZiyifYjRJ7K5c7227	intact-crc:9FB4C863B6131A28|rigid:4AMsXHfGu9APXOML/fSIrxZhDbE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P54733	uniprotkb:P14785	intact:EBI-203549|intact:EBI-1628120|uniprotkb:Q24479|uniprotkb:Q95RP5|uniprotkb:Q9V3B3|uniprotkb:Q9V456|ensemblmetazoa:FBpp0080331|ensemblmetazoa:FBpp0080332|ensemblmetazoa:FBpp0080333|ensemblmetazoa:FBpp0080334	intact:EBI-240333|uniprotkb:Q8IGR7|uniprotkb:Q9VTP6|uniprotkb:Q9VTP7|ensemblmetazoa:FBpp0075807	psi-mi:ccne_drome(display_long)|uniprotkb:CycE(gene name)|psi-mi:CycE(display_short)|uniprotkb:CG3938(orf name)	psi-mi:ccna_drome(display_long)|uniprotkb:CycA(gene name)|psi-mi:CycA(display_short)|uniprotkb:CG5940(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Gawliński et al. (2007)	pubmed:17431409|imex:IM-10935|mint:MINT-5219855	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7377033|mint:MINT-4652285|imex:IM-10935-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476959.1|refseq:NP_476960.1|refseq:NP_723924.1|refseq:NP_723925.1|refseq:NP_723926.1|flybase:FBgn0010382|dip:DIP-18331N|ensemblmetazoa:FBgn0010382(gene)|ensemblmetazoa:FBtr0080773(transcript)|ensemblmetazoa:FBtr0080774(transcript)|ensemblmetazoa:FBtr0080775(transcript)|ensemblmetazoa:FBtr0080776(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007277"(pole cell development)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035736"(cell proliferation involved in compound eye morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048665"(neuron fate specification)|go:"GO:0090210"(regulation of establishment of blood-brain barrier)|go:"GO:0097134"(cyclin E1-CDK2 complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P54733|reactome:R-DME-1538133|reactome:R-DME-187577|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-9706019|mint:MINT-4652286(identity)	refseq:NP_524030.2|flybase:FBgn0000404|dip:DIP-22019N|ensemblmetazoa:FBgn0000404(gene)|ensemblmetazoa:FBtr0076075(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0035561"(regulation of chromatin binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045169"(fusome)|go:"GO:0045170"(spectrosome)|go:"GO:0045202"(synapse)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0097124"(cyclin A2-CDK2 complex)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P14785|reactome:R-DME-1538133|reactome:R-DME-174184|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-5689880|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69273|reactome:R-DME-69563|reactome:R-DME-69656|mint:MINT-4652289(identity)	-	-	-	figure legend:F3B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2007/05/14	2014/10/16	rogid:AwK/vwBDPgICbmeNxOxrcsj5kiQ7227	rogid:Ym2ygZ2vFqtDFvZiyifYjRJ7K5c7227	intact-crc:97B7E044D94E0359|rigid:819F5vOZztYC6IXv8vN/FD5+ML8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P23572	uniprotkb:P14785	intact:EBI-108689|intact:EBI-1627558|uniprotkb:A0ANT1|uniprotkb:Q86FT5|uniprotkb:Q86FT6|uniprotkb:Q86FT7|uniprotkb:Q86FT8|uniprotkb:Q86FT9|uniprotkb:Q9TX68|uniprotkb:Q9TX69|uniprotkb:Q9TX70|uniprotkb:Q9TX71|uniprotkb:Q9TX72|uniprotkb:Q9TX73|uniprotkb:Q9TX74|uniprotkb:Q9VKX5|ensemblmetazoa:FBpp0079641	intact:EBI-240333|uniprotkb:Q8IGR7|uniprotkb:Q9VTP6|uniprotkb:Q9VTP7|ensemblmetazoa:FBpp0075807	psi-mi:cdk1_drome(display_long)|uniprotkb:Cdk1(gene name)|psi-mi:Cdk1(display_short)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:cdc2(gene name synonym)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:CG5363(orf name)	psi-mi:ccna_drome(display_long)|uniprotkb:CycA(gene name)|psi-mi:CycA(display_short)|uniprotkb:CG5940(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Gawliński et al. (2007)	pubmed:17431409|imex:IM-10935|mint:MINT-5219855	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7377119|mint:MINT-4652334|imex:IM-10935-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476797.1|flybase:FBgn0004106|dip:DIP-649N|ensemblmetazoa:FBgn0004106(gene)|ensemblmetazoa:FBtr0080051(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045169"(fusome)|go:"GO:0048142"(germarium-derived cystoblast division)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P23572|reactome:R-DME-110056|reactome:R-DME-174048|reactome:R-DME-174184|reactome:R-DME-176408|reactome:R-DME-176412|reactome:R-DME-176417|reactome:R-DME-2500257|reactome:R-DME-2565942|reactome:R-DME-2995383|reactome:R-DME-3301854|reactome:R-DME-4419969|reactome:R-DME-5687128|reactome:R-DME-6804114|reactome:R-DME-68875|reactome:R-DME-69273|reactome:R-DME-69478|reactome:R-DME-75035|reactome:R-DME-8878166|mint:MINT-4652335(identity)	refseq:NP_524030.2|flybase:FBgn0000404|dip:DIP-22019N|ensemblmetazoa:FBgn0000404(gene)|ensemblmetazoa:FBtr0076075(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0035561"(regulation of chromatin binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045169"(fusome)|go:"GO:0045170"(spectrosome)|go:"GO:0045202"(synapse)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0097124"(cyclin A2-CDK2 complex)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P14785|reactome:R-DME-1538133|reactome:R-DME-174184|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-5689880|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69273|reactome:R-DME-69563|reactome:R-DME-69656|mint:MINT-4652339(identity)	-	-	-	figure legend:F3B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2007/05/14	2014/10/16	rogid:WK4kxTRU/nlh6/LCeihCplHOZ2o7227	rogid:Ym2ygZ2vFqtDFvZiyifYjRJ7K5c7227	intact-crc:342FFE83688AC5DC|rigid:H1J319fh96mAocweFPHm6IY3uSs	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P22469	uniprotkb:P14785	intact:EBI-7376821|uniprotkb:Q9VUP1|uniprotkb:Q4V3M0|intact:MINT-4652172|uniprotkb:A0JQ32|ensemblmetazoa:FBpp0075304	intact:EBI-240333|uniprotkb:Q8IGR7|uniprotkb:Q9VTP6|uniprotkb:Q9VTP7|ensemblmetazoa:FBpp0075807	psi-mi:z600_drome(display_long)|uniprotkb:Z600(gene name)|psi-mi:Z600(display_short)|uniprotkb:Protein Fruhstart(gene name synonym)|uniprotkb:frs(gene name synonym)|uniprotkb:CG17962(orf name)	psi-mi:ccna_drome(display_long)|uniprotkb:CycA(gene name)|psi-mi:CycA(display_short)|uniprotkb:CG5940(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Gawliński et al. (2007)	pubmed:17431409|imex:IM-10935|mint:MINT-5219855	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7377057|mint:MINT-4652300|imex:IM-10935-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524083.2|flybase:FBgn0004052|ensemblmetazoa:FBgn0004052(gene)|ensemblmetazoa:FBtr0075549(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030332"(cyclin binding)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0051301"(cell division)|mint:P22469|mint:MINT-4652301(identity)	refseq:NP_524030.2|flybase:FBgn0000404|dip:DIP-22019N|ensemblmetazoa:FBgn0000404(gene)|ensemblmetazoa:FBtr0076075(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0009794"(regulation of mitotic cell cycle, embryonic)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035186"(syncytial blastoderm mitotic cell cycle)|go:"GO:0035561"(regulation of chromatin binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045169"(fusome)|go:"GO:0045170"(spectrosome)|go:"GO:0045202"(synapse)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0097124"(cyclin A2-CDK2 complex)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P14785|reactome:R-DME-1538133|reactome:R-DME-174184|reactome:R-DME-176408|reactome:R-DME-187577|reactome:R-DME-2559582|reactome:R-DME-2559586|reactome:R-DME-5689880|reactome:R-DME-6804116|reactome:R-DME-6804756|reactome:R-DME-68911|reactome:R-DME-68949|reactome:R-DME-69017|reactome:R-DME-69273|reactome:R-DME-69563|reactome:R-DME-69656|mint:MINT-4652305(identity)	-	comment:mint|function:Not known	-	figure legend:F3B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2007/05/14	2014/10/16	rogid:D+QltlrWlC3/1YRYluNLdX9xml07227	rogid:Ym2ygZ2vFqtDFvZiyifYjRJ7K5c7227	intact-crc:C47C7CFEB0922DA7|rigid:4AMsXHfGu9APXOML/fSIrxZhDbE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P23572	uniprotkb:P54733	intact:EBI-108689|intact:EBI-1627558|uniprotkb:A0ANT1|uniprotkb:Q86FT5|uniprotkb:Q86FT6|uniprotkb:Q86FT7|uniprotkb:Q86FT8|uniprotkb:Q86FT9|uniprotkb:Q9TX68|uniprotkb:Q9TX69|uniprotkb:Q9TX70|uniprotkb:Q9TX71|uniprotkb:Q9TX72|uniprotkb:Q9TX73|uniprotkb:Q9TX74|uniprotkb:Q9VKX5|ensemblmetazoa:FBpp0079641	intact:EBI-203549|intact:EBI-1628120|uniprotkb:Q24479|uniprotkb:Q95RP5|uniprotkb:Q9V3B3|uniprotkb:Q9V456|ensemblmetazoa:FBpp0080331|ensemblmetazoa:FBpp0080332|ensemblmetazoa:FBpp0080333|ensemblmetazoa:FBpp0080334	psi-mi:cdk1_drome(display_long)|uniprotkb:Cdk1(gene name)|psi-mi:Cdk1(display_short)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:cdc2(gene name synonym)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:CG5363(orf name)	psi-mi:ccne_drome(display_long)|uniprotkb:CycE(gene name)|psi-mi:CycE(display_short)|uniprotkb:CG3938(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Gawliński et al. (2007)	pubmed:17431409|imex:IM-10935|mint:MINT-5219855	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7377132|mint:MINT-4652345|imex:IM-10935-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476797.1|flybase:FBgn0004106|dip:DIP-649N|ensemblmetazoa:FBgn0004106(gene)|ensemblmetazoa:FBtr0080051(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045169"(fusome)|go:"GO:0048142"(germarium-derived cystoblast division)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P23572|reactome:R-DME-110056|reactome:R-DME-174048|reactome:R-DME-174184|reactome:R-DME-176408|reactome:R-DME-176412|reactome:R-DME-176417|reactome:R-DME-2500257|reactome:R-DME-2565942|reactome:R-DME-2995383|reactome:R-DME-3301854|reactome:R-DME-4419969|reactome:R-DME-5687128|reactome:R-DME-6804114|reactome:R-DME-68875|reactome:R-DME-69273|reactome:R-DME-69478|reactome:R-DME-75035|reactome:R-DME-8878166|mint:MINT-4652350(identity)	refseq:NP_476959.1|refseq:NP_476960.1|refseq:NP_723924.1|refseq:NP_723925.1|refseq:NP_723926.1|flybase:FBgn0010382|dip:DIP-18331N|ensemblmetazoa:FBgn0010382(gene)|ensemblmetazoa:FBtr0080773(transcript)|ensemblmetazoa:FBtr0080774(transcript)|ensemblmetazoa:FBtr0080775(transcript)|ensemblmetazoa:FBtr0080776(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007277"(pole cell development)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035736"(cell proliferation involved in compound eye morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048665"(neuron fate specification)|go:"GO:0090210"(regulation of establishment of blood-brain barrier)|go:"GO:0097134"(cyclin E1-CDK2 complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P54733|reactome:R-DME-1538133|reactome:R-DME-187577|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-9706019|mint:MINT-4652346(identity)	-	-	-	figure legend:F3B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2007/05/14	2014/10/16	rogid:WK4kxTRU/nlh6/LCeihCplHOZ2o7227	rogid:AwK/vwBDPgICbmeNxOxrcsj5kiQ7227	intact-crc:141139C20CCC5E2F|rigid:pvYn9pnjx9q/bCgOIgx0ruMBxBI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P22469	uniprotkb:P23572	intact:EBI-7376821|uniprotkb:Q9VUP1|uniprotkb:Q4V3M0|intact:MINT-4652172|uniprotkb:A0JQ32|ensemblmetazoa:FBpp0075304	intact:EBI-108689|intact:EBI-1627558|uniprotkb:A0ANT1|uniprotkb:Q86FT5|uniprotkb:Q86FT6|uniprotkb:Q86FT7|uniprotkb:Q86FT8|uniprotkb:Q86FT9|uniprotkb:Q9TX68|uniprotkb:Q9TX69|uniprotkb:Q9TX70|uniprotkb:Q9TX71|uniprotkb:Q9TX72|uniprotkb:Q9TX73|uniprotkb:Q9TX74|uniprotkb:Q9VKX5|ensemblmetazoa:FBpp0079641	psi-mi:z600_drome(display_long)|uniprotkb:Z600(gene name)|psi-mi:Z600(display_short)|uniprotkb:Protein Fruhstart(gene name synonym)|uniprotkb:frs(gene name synonym)|uniprotkb:CG17962(orf name)	psi-mi:cdk1_drome(display_long)|uniprotkb:Cdk1(gene name)|psi-mi:Cdk1(display_short)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:cdc2(gene name synonym)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:CG5363(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Gawliński et al. (2007)	pubmed:17431409|imex:IM-10935|mint:MINT-5219855	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7377084|mint:MINT-4652323|imex:IM-10935-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524083.2|flybase:FBgn0004052|ensemblmetazoa:FBgn0004052(gene)|ensemblmetazoa:FBtr0075549(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030332"(cyclin binding)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0051301"(cell division)|mint:P22469|mint:MINT-4652328(identity)	refseq:NP_476797.1|flybase:FBgn0004106|dip:DIP-649N|ensemblmetazoa:FBgn0004106(gene)|ensemblmetazoa:FBtr0080051(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0001700"(embryonic development via the syncytial blastoderm)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045169"(fusome)|go:"GO:0048142"(germarium-derived cystoblast division)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P23572|reactome:R-DME-110056|reactome:R-DME-174048|reactome:R-DME-174184|reactome:R-DME-176408|reactome:R-DME-176412|reactome:R-DME-176417|reactome:R-DME-2500257|reactome:R-DME-2565942|reactome:R-DME-2995383|reactome:R-DME-3301854|reactome:R-DME-4419969|reactome:R-DME-5687128|reactome:R-DME-6804114|reactome:R-DME-68875|reactome:R-DME-69273|reactome:R-DME-69478|reactome:R-DME-75035|reactome:R-DME-8878166|mint:MINT-4652324(identity)	-	comment:mint|function:Not known	-	figure legend:F3B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	-	2007/05/14	2014/10/16	rogid:D+QltlrWlC3/1YRYluNLdX9xml07227	rogid:WK4kxTRU/nlh6/LCeihCplHOZ2o7227	intact-crc:3EF3E9F7D3FC2ED5|rigid:JVwk7ii4bnOrQ95kDpQ4hiSE8Wk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P22469	uniprotkb:P54733	intact:EBI-7376821|uniprotkb:Q9VUP1|uniprotkb:Q4V3M0|intact:MINT-4652172|uniprotkb:A0JQ32|ensemblmetazoa:FBpp0075304	intact:EBI-203549|intact:EBI-1628120|uniprotkb:Q24479|uniprotkb:Q95RP5|uniprotkb:Q9V3B3|uniprotkb:Q9V456|ensemblmetazoa:FBpp0080331|ensemblmetazoa:FBpp0080332|ensemblmetazoa:FBpp0080333|ensemblmetazoa:FBpp0080334	psi-mi:z600_drome(display_long)|uniprotkb:Z600(gene name)|psi-mi:Z600(display_short)|uniprotkb:Protein Fruhstart(gene name synonym)|uniprotkb:frs(gene name synonym)|uniprotkb:CG17962(orf name)	psi-mi:ccne_drome(display_long)|uniprotkb:CycE(gene name)|psi-mi:CycE(display_short)|uniprotkb:CG3938(orf name)	psi-mi:"MI:0018"(two hybrid)	Gawliński et al. (2007)	pubmed:17431409|imex:IM-10935|mint:MINT-5219855	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7377220|mint:MINT-4652403|imex:IM-10935-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524083.2|flybase:FBgn0004052|ensemblmetazoa:FBgn0004052(gene)|ensemblmetazoa:FBtr0075549(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030332"(cyclin binding)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0051301"(cell division)|mint:P22469|mint:MINT-4652404(identity)	refseq:NP_476959.1|refseq:NP_476960.1|refseq:NP_723924.1|refseq:NP_723925.1|refseq:NP_723926.1|flybase:FBgn0010382|dip:DIP-18331N|ensemblmetazoa:FBgn0010382(gene)|ensemblmetazoa:FBtr0080773(transcript)|ensemblmetazoa:FBtr0080774(transcript)|ensemblmetazoa:FBtr0080775(transcript)|ensemblmetazoa:FBtr0080776(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007277"(pole cell development)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0007400"(neuroblast fate determination)|go:"GO:0007419"(ventral cord development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035736"(cell proliferation involved in compound eye morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045035"(sensory organ precursor cell division)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048665"(neuron fate specification)|go:"GO:0090210"(regulation of establishment of blood-brain barrier)|go:"GO:0097134"(cyclin E1-CDK2 complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:P54733|reactome:R-DME-1538133|reactome:R-DME-187577|reactome:R-DME-2559586|reactome:R-DME-6804116|reactome:R-DME-69017|reactome:R-DME-69202|reactome:R-DME-69563|reactome:R-DME-9706019|mint:MINT-4652410(identity)	-	comment:mint|function:Not known	-	figure legend:SF1A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/05/14	2014/10/16	rogid:D+QltlrWlC3/1YRYluNLdX9xml07227	rogid:AwK/vwBDPgICbmeNxOxrcsj5kiQ7227	intact-crc:A15BAB402E562E86|rigid:+pddkSaKfLb4RAhSvpjfIkrA+IU	false	tag:?-?(MINT-4652406)	tag:?-?(MINT-4652412)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22469	uniprotkb:Q7K0D8	intact:EBI-7376821|uniprotkb:Q9VUP1|uniprotkb:Q4V3M0|intact:MINT-4652172|uniprotkb:A0JQ32|ensemblmetazoa:FBpp0075304	intact:EBI-194571|ensemblmetazoa:FBpp0087861	psi-mi:z600_drome(display_long)|uniprotkb:Z600(gene name)|psi-mi:Z600(display_short)|uniprotkb:Protein Fruhstart(gene name synonym)|uniprotkb:frs(gene name synonym)|uniprotkb:CG17962(orf name)	psi-mi:nup50_drome(display_long)|uniprotkb:Nup50(gene name)|psi-mi:Nup50(display_short)|uniprotkb:50 kDa nucleoporin(gene name synonym)|uniprotkb:CG2158(orf name)	psi-mi:"MI:0018"(two hybrid)	Gawliński et al. (2007)	pubmed:17431409|imex:IM-10935|mint:MINT-5219855	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7377202|mint:MINT-4652374|imex:IM-10935-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524083.2|flybase:FBgn0004052|ensemblmetazoa:FBgn0004052(gene)|ensemblmetazoa:FBtr0075549(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030332"(cyclin binding)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0051301"(cell division)|mint:P22469|mint:MINT-4652379(identity)	refseq:NP_610355.1|flybase:FBgn0033264|dip:DIP-21255N|ensemblmetazoa:FBgn0033264(gene)|ensemblmetazoa:FBtr0088783(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035080"(heat shock-mediated polytene chromosome puffing)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051028"(mRNA transport)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015007("NUP50 (Nucleoporin 50 kDa)")|mint:Q7K0D8|reactome:R-DME-159227|reactome:R-DME-159230|reactome:R-DME-159231|reactome:R-DME-159236|reactome:R-DME-3301854|reactome:R-DME-3371453|reactome:R-DME-4551638|reactome:R-DME-4615885|reactome:R-DME-5578749|mint:MINT-4652375(identity)	-	comment:mint|function:Not known	-	figure legend:SF1A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/05/14	2014/10/16	rogid:D+QltlrWlC3/1YRYluNLdX9xml07227	rogid:M9Xjq9uZLH9wdlorMu1pk3MYNQI7227	intact-crc:0B8BF0A7489A298D|rigid:Z3ZiE5GtJJ3s482c5O64IsD3YwM	false	tag:?-?(MINT-4652400)	tag:?-?(MINT-4652397)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22469	uniprotkb:Q9W1X4	intact:EBI-7376821|uniprotkb:Q9VUP1|uniprotkb:Q4V3M0|intact:MINT-4652172|uniprotkb:A0JQ32|ensemblmetazoa:FBpp0075304	intact:EBI-102000|uniprotkb:Q8T3K4|ensemblmetazoa:FBpp0071905	psi-mi:z600_drome(display_long)|uniprotkb:Z600(gene name)|psi-mi:Z600(display_short)|uniprotkb:Protein Fruhstart(gene name synonym)|uniprotkb:frs(gene name synonym)|uniprotkb:CG17962(orf name)	psi-mi:nu214_drome(display_long)|uniprotkb:Nup214(gene name)|psi-mi:Nup214(display_short)|uniprotkb:CG3820(orf name)|uniprotkb:Nucleoporin Nup214(gene name synonym)|uniprotkb:214 kDa nucleoporin(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Gawliński et al. (2007)	pubmed:17431409|imex:IM-10935|mint:MINT-5219855	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7377284|mint:MINT-4652435|imex:IM-10935-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524083.2|flybase:FBgn0004052|ensemblmetazoa:FBgn0004052(gene)|ensemblmetazoa:FBtr0075549(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030332"(cyclin binding)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0051301"(cell division)|mint:P22469|mint:MINT-4652442(identity)	refseq:NP_652039.2|flybase:FBgn0010660|reactome:R-DME-159236|reactome:R-DME-3301854|reactome:R-DME-3371453|reactome:R-DME-450520|reactome:R-DME-4551638|reactome:R-DME-4615885|reactome:R-DME-5578749|reactome:R-DME-9615933|ensemblmetazoa:FBgn0010660(gene)|ensemblmetazoa:FBtr0071996(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0090204"(protein localization to nuclear pore)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR026054|mint:Q9W1X4|reactome:R-DME-159227|reactome:R-DME-159230|reactome:R-DME-159231|dip:DIP-18878N|mint:MINT-4652436(identity)	-	comment:mint|function:Not known	-	figure legend:SF1A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/05/14	2014/10/16	rogid:D+QltlrWlC3/1YRYluNLdX9xml07227	rogid:qj9UpG1Z8BpkepUEAt9c2rlYLEk7227	intact-crc:2AD007B762634E3B|rigid:YIXhTZnttDaTy9zJ2OXN4ngtY8c	false	tag:?-?(MINT-4652444)	tag:?-?(MINT-4652438)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22469	uniprotkb:A0A0B4K7J2	intact:EBI-7376821|uniprotkb:Q9VUP1|uniprotkb:Q4V3M0|intact:MINT-4652172|uniprotkb:A0JQ32|ensemblmetazoa:FBpp0075304	intact:EBI-191234|intact:EBI-500124|uniprotkb:D3DMF2|uniprotkb:Q8SWV7|uniprotkb:Q9VBU7|ensemblmetazoa:FBpp0293235	psi-mi:z600_drome(display_long)|uniprotkb:Z600(gene name)|psi-mi:Z600(display_short)|uniprotkb:Protein Fruhstart(gene name synonym)|uniprotkb:frs(gene name synonym)|uniprotkb:CG17962(orf name)	psi-mi:rbp2_drome(display_long)|uniprotkb:Nup358(gene name)|psi-mi:Nup358(display_short)|uniprotkb:RanBP2(gene name synonym)|uniprotkb:CG11856(orf name)|uniprotkb:358 kDa nucleoporin(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup358(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Gawliński et al. (2007)	pubmed:17431409|imex:IM-10935|mint:MINT-5219855	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7377317|mint:MINT-4652450|imex:IM-10935-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524083.2|flybase:FBgn0004052|ensemblmetazoa:FBgn0004052(gene)|ensemblmetazoa:FBtr0075549(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030332"(cyclin binding)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0051301"(cell division)|mint:P22469|mint:MINT-4652457(identity)	flybase:FBgn0039302|refseq:NP_001247302.1|refseq:NP_651361.2|go:"GO:0046872"(metal ion binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903827"|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036443|mint:A0A0B4K7J2|ensemblmetazoa:FBgn0039302(gene)|ensemblmetazoa:FBtr0304692(transcript)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007281"(germ cell development)|go:"GO:0007419"(ventral cord development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010528"(regulation of transposition)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0035626"(juvenile hormone mediated signaling pathway)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|mint:MINT-4652451(identity)	-	comment:mint|function:Not known	-	figure legend:SF1A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/05/14	2018/04/06	rogid:D+QltlrWlC3/1YRYluNLdX9xml07227	rogid:zb4ucBC1Rt7Y7AabwnrCvMwmCoQ7227	intact-crc:2017A436C851EF5A|rigid:eAoqn5fjfUYhLZ0KVWsbvX8AKDk	false	tag:?-?(MINT-4652459)	tag:?-?(MINT-4652453)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22469	uniprotkb:Q9V6B9	intact:EBI-7376821|uniprotkb:Q9VUP1|uniprotkb:Q4V3M0|intact:MINT-4652172|uniprotkb:A0JQ32|ensemblmetazoa:FBpp0075304	intact:EBI-179307|ensemblmetazoa:FBpp0087063	psi-mi:z600_drome(display_long)|uniprotkb:Z600(gene name)|psi-mi:Z600(display_short)|uniprotkb:Protein Fruhstart(gene name synonym)|uniprotkb:frs(gene name synonym)|uniprotkb:CG17962(orf name)	psi-mi:nup54_drome(display_long)|uniprotkb:CG8831(orf name)|uniprotkb:Nup54(gene name)|psi-mi:Nup54(display_short)	psi-mi:"MI:0018"(two hybrid)	Gawliński et al. (2007)	pubmed:17431409|imex:IM-10935|mint:MINT-5219855	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7377238|mint:MINT-4652418|imex:IM-10935-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524083.2|flybase:FBgn0004052|ensemblmetazoa:FBgn0004052(gene)|ensemblmetazoa:FBtr0075549(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030332"(cyclin binding)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0051301"(cell division)|mint:P22469|mint:MINT-4652425(identity)	refseq:NP_610783.1|flybase:FBgn0033737|dip:DIP-19285N|ensemblmetazoa:FBgn0033737(gene)|ensemblmetazoa:FBtr0087952(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006605"(protein targeting)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025712|interpro:IPR040985|mint:Q9V6B9|reactome:R-DME-159227|reactome:R-DME-159230|reactome:R-DME-159231|reactome:R-DME-159236|reactome:R-DME-3301854|reactome:R-DME-3371453|reactome:R-DME-4551638|reactome:R-DME-4615885|reactome:R-DME-5578749|mint:MINT-4652419(identity)	-	comment:mint|function:Not known	-	figure legend:SF1A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/05/14	2014/10/16	rogid:D+QltlrWlC3/1YRYluNLdX9xml07227	rogid:0RSPWkJnRddLDMAOCRvpHWcUlSo7227	intact-crc:D89113BFC1412211|rigid:AgSFCVT3ETotAdBi8YLP+ZwQ09Y	false	tag:?-?(MINT-4652427)	tag:?-?(MINT-4652421)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22469	uniprotkb:Q9TVM2	intact:EBI-7376821|uniprotkb:Q9VUP1|uniprotkb:Q4V3M0|intact:MINT-4652172|uniprotkb:A0JQ32|ensemblmetazoa:FBpp0075304	intact:EBI-133375|uniprotkb:Q9I7N7|uniprotkb:Q9U699|ensemblmetazoa:FBpp0079278|ensemblmetazoa:FBpp0312321	psi-mi:z600_drome(display_long)|uniprotkb:Z600(gene name)|psi-mi:Z600(display_short)|uniprotkb:Protein Fruhstart(gene name synonym)|uniprotkb:frs(gene name synonym)|uniprotkb:CG17962(orf name)	psi-mi:xpo1_drome(display_long)|uniprotkb:emb(gene name)|psi-mi:emb(display_short)|uniprotkb:Crm1(gene name synonym)|uniprotkb:CG13387(orf name)|uniprotkb:Chromosome region maintenance 1 protein(gene name synonym)|uniprotkb:Protein embargoed(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Gawliński et al. (2007)	pubmed:17431409|imex:IM-10935|mint:MINT-5219855	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7377453|mint:MINT-4652544|imex:IM-10935-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524083.2|flybase:FBgn0004052|ensemblmetazoa:FBgn0004052(gene)|ensemblmetazoa:FBtr0075549(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030332"(cyclin binding)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0051301"(cell division)|mint:P22469|mint:MINT-4652549(identity)	refseq:NP_001303316.1|refseq:NP_723391.2|flybase:FBgn0020497|ensemblmetazoa:FBgn0020497(gene)|ensemblmetazoa:FBtr0079663(transcript)|ensemblmetazoa:FBtr0346708(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007099"(centriole replication)|go:"GO:0007275"(multicellular organism development)|go:"GO:0015031"(protein transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1900037"(regulation of cellular response to hypoxia)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|mint:Q9TVM2|reactome:R-DME-3769402|reactome:R-DME-450520|reactome:R-DME-5687128|reactome:R-DME-69273|reactome:R-DME-9707616|reactome:R-DME-9634638|dip:DIP-21235N|mint:MINT-4652545(identity)	-	comment:mint|function:Not known	-	figure legend:SF1B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/14	2014/10/16	rogid:D+QltlrWlC3/1YRYluNLdX9xml07227	rogid:DgxTsMZ193HLXAKrApTP5Ut+4R87227	intact-crc:DF9F707A2C227D22|rigid:bYOQRk48vbpP8IUnFOeYqzPwzBA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q86NK4	uniprotkb:P22469	intact:EBI-7377381|intact:MINT-4652497	intact:EBI-7376821|uniprotkb:Q9VUP1|uniprotkb:Q4V3M0|intact:MINT-4652172|uniprotkb:A0JQ32|ensemblmetazoa:FBpp0075304	psi-mi:q86nk4_drome(display_long)|uniprotkb:msk(gene name)|psi-mi:msk(display_short)|uniprotkb:CG7935(orf name)	psi-mi:z600_drome(display_long)|uniprotkb:Z600(gene name)|psi-mi:Z600(display_short)|uniprotkb:Protein Fruhstart(gene name synonym)|uniprotkb:frs(gene name synonym)|uniprotkb:CG17962(orf name)	psi-mi:"MI:0004"(affinity chromatography technology)	Gawliński et al. (2007)	pubmed:17431409|imex:IM-10935|mint:MINT-5219855	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7377375|mint:MINT-4652480|imex:IM-10935-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	flybase:FBgn0026252|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007474"(imaginal disc-derived wing vein specification)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0008586"(imaginal disc-derived wing vein morphogenesis)|go:"GO:0015030"(Cajal body)|go:"GO:0016203"(muscle attachment)|go:"GO:0016318"(ommatidial rotation)|go:"GO:0030576"(Cajal body organization)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035311"(wing cell fate specification)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045465"(R8 cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048749"(compound eye development)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:Q86NK4|mint:MINT-4652481(identity)	refseq:NP_524083.2|flybase:FBgn0004052|ensemblmetazoa:FBgn0004052(gene)|ensemblmetazoa:FBtr0075549(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030332"(cyclin binding)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0051301"(cell division)|mint:P22469|mint:MINT-4652487(identity)	-	comment:mint	comment:mint|function:Not known	figure legend:SF1B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/14	2014/10/16	rogid:2Nraxy60a6QY8IIlcdhrz8i4jhI7227	rogid:D+QltlrWlC3/1YRYluNLdX9xml07227	intact-crc:56A480DC13685D27|rigid:9Ur215h/2zD3tJggT2K/l+KjJ/Y	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22469	uniprotkb:Q9I7R5	intact:EBI-7376821|uniprotkb:Q9VUP1|uniprotkb:Q4V3M0|intact:MINT-4652172|uniprotkb:A0JQ32|ensemblmetazoa:FBpp0075304	intact:EBI-3406979|ensemblmetazoa:FBpp0075072	psi-mi:z600_drome(display_long)|uniprotkb:Z600(gene name)|psi-mi:Z600(display_short)|uniprotkb:Protein Fruhstart(gene name synonym)|uniprotkb:frs(gene name synonym)|uniprotkb:CG17962(orf name)	psi-mi:q9i7r5_drome(display_long)|uniprotkb:Apl(gene name)|psi-mi:Apl(display_short)|uniprotkb:5(gene name synonym)|uniprotkb:CG18218(gene name synonym)|uniprotkb:CG18861(gene name synonym)|uniprotkb:Dmel\CG32165(gene name synonym)|uniprotkb:Imp4(gene name synonym)|uniprotkb:anon-73Bb(gene name synonym)|uniprotkb:CG32165(orf name)|uniprotkb:Dmel_CG32165(orf name)	psi-mi:"MI:0004"(affinity chromatography technology)	Gawliński et al. (2007)	pubmed:17431409|imex:IM-10935|mint:MINT-5219855	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7377441|mint:MINT-4652517|imex:IM-10935-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524083.2|flybase:FBgn0004052|ensemblmetazoa:FBgn0004052(gene)|ensemblmetazoa:FBtr0075549(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030332"(cyclin binding)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0051301"(cell division)|mint:P22469|mint:MINT-4652522(identity)	refseq:NP_730182.1|flybase:FBgn0042178|dip:DIP-23396N|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|mint:Q9I7R5|ensemblmetazoa:FBgn0042178(gene)|ensemblmetazoa:FBtr0075312(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|mint:MINT-4652518(identity)	-	comment:mint|function:Not known	-	figure legend:SF1B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/14	2014/10/16	rogid:D+QltlrWlC3/1YRYluNLdX9xml07227	rogid:TJVI92KaeifkpOHbdzl3rfpDlP87227	intact-crc:A7979A958C812E47|rigid:WbRzIlHxNUJiz33OArxM/l0cvcs	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P22469	uniprotkb:O18388	intact:EBI-7376821|uniprotkb:Q9VUP1|uniprotkb:Q4V3M0|intact:MINT-4652172|uniprotkb:A0JQ32|ensemblmetazoa:FBpp0075304	intact:EBI-155558|uniprotkb:Q540Y0|uniprotkb:Q9V3E6|ensemblmetazoa:FBpp0080922|ensemblmetazoa:FBpp0294035|ensemblmetazoa:FBpp0294036|ensemblmetazoa:FBpp0294037|ensemblmetazoa:FBpp0294038	psi-mi:z600_drome(display_long)|uniprotkb:Z600(gene name)|psi-mi:Z600(display_short)|uniprotkb:Protein Fruhstart(gene name synonym)|uniprotkb:frs(gene name synonym)|uniprotkb:CG17962(orf name)	psi-mi:imb_drome(display_long)|uniprotkb:"Fs(2)Ket"(gene name)|psi-mi:"Fs(2)Ket"(display_short)|uniprotkb:CG2637(orf name)|uniprotkb:Karyopherin subunit beta(gene name synonym)|uniprotkb:Protein ketel(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Gawliński et al. (2007)	pubmed:17431409|imex:IM-10935|mint:MINT-5219855	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7377465|mint:MINT-4652554|imex:IM-10935-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524083.2|flybase:FBgn0004052|ensemblmetazoa:FBgn0004052(gene)|ensemblmetazoa:FBtr0075549(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0007370"(ventral furrow formation)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030332"(cyclin binding)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0051301"(cell division)|mint:P22469|mint:MINT-4652559(identity)	refseq:NP_001246108.1|refseq:NP_001246109.1|refseq:NP_001246110.1|refseq:NP_001246111.1|refseq:NP_477496.1|flybase:FBgn0262743|dip:DIP-23049N|ensemblmetazoa:FBgn0262743(gene)|ensemblmetazoa:FBtr0081392(transcript)|ensemblmetazoa:FBtr0305584(transcript)|ensemblmetazoa:FBtr0305585(transcript)|ensemblmetazoa:FBtr0305586(transcript)|ensemblmetazoa:FBtr0305587(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0007304"(chorion-containing eggshell formation)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043186"(P granule)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:O18388|reactome:R-DME-140342|reactome:R-DME-1655829|reactome:R-DME-2995383|reactome:R-DME-6798695|reactome:R-DME-909733|mint:MINT-4652555(identity)	-	comment:mint|function:Not known	-	figure legend:SF1B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/14	2014/10/16	rogid:D+QltlrWlC3/1YRYluNLdX9xml07227	rogid:aOINvxY8YoLIUhNwXg/7We/Vvtg7227	intact-crc:E780E459531BBADD|rigid:iB8/0B3atALZYYkEyNULX3aPsyE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0427"(Identification by mass spectrometry)