#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P49454 uniprotkb:Q8WUM0 intact:EBI-968343|ensembl:ENSP00000355922|uniprotkb:Q13171|uniprotkb:Q13246|uniprotkb:Q5VVM7|intact:EBI-2563723|intact:EBI-21028103 intact:EBI-295695|uniprotkb:Q5T8N0|uniprotkb:Q9H9W2|uniprotkb:Q9NV71|uniprotkb:Q9NVC4|uniprotkb:B2RAZ8|ensembl:ENSP00000261396 psi-mi:cenpf_human(display_long)|uniprotkb:CENPF(gene name)|psi-mi:CENPF(display_short)|uniprotkb:Kinetochore protein CENPF(gene name synonym)|uniprotkb:Mitosin(gene name synonym)|uniprotkb:AH antigen(gene name synonym) psi-mi:nu133_human(display_long)|uniprotkb:NUP133(gene name)|psi-mi:NUP133(display_short)|uniprotkb:Nucleoporin Nup133(gene name synonym)|uniprotkb:133 kDa nucleoporin(gene name synonym) psi-mi:"MI:0018"(two hybrid) Zuccolo et al. (2007) pubmed:17363900|imex:IM-13993|mint:MINT-5219767 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7328986|mint:MINT-4788132|imex:IM-13993-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007517"(muscle organ development)|ensembl:ENSG00000117724(gene)|ensembl:ENST00000366955(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0001822"(kidney development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0042493"|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0070840"(dynein complex binding)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0097539"(ciliary transition fiber)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR018302|interpro:IPR018463|interpro:IPR019513|interpro:IPR043513|mint:P49454|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-156711|refseq:NP_057427.3|refseq:XP_016855575.1|mint:MINT-4788134(identity) refseq:NP_060700.2|ensembl:ENSG00000069248(gene)|ensembl:ENST00000261396(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0061053"(somite development)|go:"GO:0072006"(nephron development)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037624|mint:Q8WUM0|rcsb pdb:1XKS|rcsb pdb:3CQC|rcsb pdb:3CQG|rcsb pdb:3I4R|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025|mint:MINT-4788133(identity) - - - figure legend:NFA|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/05/29 2019/01/23 rogid:gPlJiOCF1/MAVT80oKwlQlLgluo9606 rogid:J89Ja9KNryxKNUd9rqNbi8EC09g9606 intact-crc:97C4AD47CBDF01A8|rigid:+3nU3hkbMtY1MUrBNwivMYXfTQk false binding-associated region:2548-2969(MINT-4788142)|tag:?-?(MINT-4788138) tag:?-?(MINT-4788145) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P49454 uniprotkb:Q8WUM0 intact:EBI-968343|ensembl:ENSP00000355922|uniprotkb:Q13171|uniprotkb:Q13246|uniprotkb:Q5VVM7|intact:EBI-2563723|intact:EBI-21028103 intact:EBI-295695|uniprotkb:Q5T8N0|uniprotkb:Q9H9W2|uniprotkb:Q9NV71|uniprotkb:Q9NVC4|uniprotkb:B2RAZ8|ensembl:ENSP00000261396 psi-mi:cenpf_human(display_long)|uniprotkb:CENPF(gene name)|psi-mi:CENPF(display_short)|uniprotkb:Kinetochore protein CENPF(gene name synonym)|uniprotkb:Mitosin(gene name synonym)|uniprotkb:AH antigen(gene name synonym) psi-mi:nu133_human(display_long)|uniprotkb:NUP133(gene name)|psi-mi:NUP133(display_short)|uniprotkb:Nucleoporin Nup133(gene name synonym)|uniprotkb:133 kDa nucleoporin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zuccolo et al. (2007) pubmed:17363900|imex:IM-13993|mint:MINT-5219767 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7329356|mint:MINT-4788150|imex:IM-13993-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007517"(muscle organ development)|ensembl:ENSG00000117724(gene)|ensembl:ENST00000366955(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0001822"(kidney development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0042493"|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0070840"(dynein complex binding)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0097539"(ciliary transition fiber)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR018302|interpro:IPR018463|interpro:IPR019513|interpro:IPR043513|mint:P49454|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-156711|refseq:NP_057427.3|refseq:XP_016855575.1|mint:MINT-4788156(identity) refseq:NP_060700.2|ensembl:ENSG00000069248(gene)|ensembl:ENST00000261396(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0061053"(somite development)|go:"GO:0072006"(nephron development)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037624|mint:Q8WUM0|rcsb pdb:1XKS|rcsb pdb:3CQC|rcsb pdb:3CQG|rcsb pdb:3I4R|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025|mint:MINT-4788151(identity) - - - figure legend:F1A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2007/05/29 2019/01/23 rogid:gPlJiOCF1/MAVT80oKwlQlLgluo9606 rogid:J89Ja9KNryxKNUd9rqNbi8EC09g9606 intact-crc:B56654EAA7C08E8A|rigid:sv4SKsiFm+AUB6WOKFLSyo2KnKI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49454 uniprotkb:P57740 intact:EBI-968343|ensembl:ENSP00000355922|uniprotkb:Q13171|uniprotkb:Q13246|uniprotkb:Q5VVM7|intact:EBI-2563723|intact:EBI-21028103 intact:EBI-295687|uniprotkb:B4DZ67|uniprotkb:Q6PJE1|intact:EBI-10966404|ensembl:ENSP00000229179 psi-mi:cenpf_human(display_long)|uniprotkb:CENPF(gene name)|psi-mi:CENPF(display_short)|uniprotkb:Kinetochore protein CENPF(gene name synonym)|uniprotkb:Mitosin(gene name synonym)|uniprotkb:AH antigen(gene name synonym) psi-mi:nu107_human(display_long)|uniprotkb:NUP107(gene name)|psi-mi:NUP107(display_short)|uniprotkb:Nucleoporin Nup107(gene name synonym)|uniprotkb:107 kDa nucleoporin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zuccolo et al. (2007) pubmed:17363900|imex:IM-13993|mint:MINT-5219767 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7329356|mint:MINT-4788150|imex:IM-13993-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007517"(muscle organ development)|ensembl:ENSG00000117724(gene)|ensembl:ENST00000366955(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0001822"(kidney development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0042493"|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0070840"(dynein complex binding)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0097539"(ciliary transition fiber)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR018302|interpro:IPR018463|interpro:IPR019513|interpro:IPR043513|mint:P49454|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-156711|refseq:NP_057427.3|refseq:XP_016855575.1|mint:MINT-4788156(identity) refseq:NP_065134.1|refseq:NP_001317121.1|ensembl:ENSG00000111581(gene)|ensembl:ENST00000229179(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008585"(female gonad development)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0072006"(nephron development)|interpro:IPR007252(Nuclear pore protein 84/107)|mint:P57740|rcsb pdb:3CQC|rcsb pdb:3CQG|rcsb pdb:3I4R|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025|mint:MINT-4792442(identity) - - - figure legend:F1A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2007/05/29 2019/01/23 rogid:gPlJiOCF1/MAVT80oKwlQlLgluo9606 rogid:76eAOFdL5JLBp0giaH8nhc3BMEI9606 intact-crc:B56654EAA7C08E8A|rigid:sv4SKsiFm+AUB6WOKFLSyo2KnKI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49454 uniprotkb:Q8WUM0 intact:EBI-968343|ensembl:ENSP00000355922|uniprotkb:Q13171|uniprotkb:Q13246|uniprotkb:Q5VVM7|intact:EBI-2563723|intact:EBI-21028103 intact:EBI-295695|uniprotkb:Q5T8N0|uniprotkb:Q9H9W2|uniprotkb:Q9NV71|uniprotkb:Q9NVC4|uniprotkb:B2RAZ8|ensembl:ENSP00000261396 psi-mi:cenpf_human(display_long)|uniprotkb:CENPF(gene name)|psi-mi:CENPF(display_short)|uniprotkb:Kinetochore protein CENPF(gene name synonym)|uniprotkb:Mitosin(gene name synonym)|uniprotkb:AH antigen(gene name synonym) psi-mi:nu133_human(display_long)|uniprotkb:NUP133(gene name)|psi-mi:NUP133(display_short)|uniprotkb:Nucleoporin Nup133(gene name synonym)|uniprotkb:133 kDa nucleoporin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zuccolo et al. (2007) pubmed:17363900|imex:IM-13993|mint:MINT-5219767 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7329356|mint:MINT-4788150|imex:IM-13993-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007517"(muscle organ development)|ensembl:ENSG00000117724(gene)|ensembl:ENST00000366955(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0001822"(kidney development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0042493"|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0070840"(dynein complex binding)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0097539"(ciliary transition fiber)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR018302|interpro:IPR018463|interpro:IPR019513|interpro:IPR043513|mint:P49454|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-156711|refseq:NP_057427.3|refseq:XP_016855575.1|mint:MINT-4788156(identity) refseq:NP_060700.2|ensembl:ENSG00000069248(gene)|ensembl:ENST00000261396(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0061053"(somite development)|go:"GO:0072006"(nephron development)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037624|mint:Q8WUM0|rcsb pdb:1XKS|rcsb pdb:3CQC|rcsb pdb:3CQG|rcsb pdb:3I4R|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025|mint:MINT-4792447(identity) - - - figure legend:F1A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2007/05/29 2019/01/23 rogid:gPlJiOCF1/MAVT80oKwlQlLgluo9606 rogid:J89Ja9KNryxKNUd9rqNbi8EC09g9606 intact-crc:B56654EAA7C08E8A|rigid:sv4SKsiFm+AUB6WOKFLSyo2KnKI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WUM0 uniprotkb:P57740 intact:EBI-295695|uniprotkb:Q5T8N0|uniprotkb:Q9H9W2|uniprotkb:Q9NV71|uniprotkb:Q9NVC4|uniprotkb:B2RAZ8|ensembl:ENSP00000261396 intact:EBI-295687|uniprotkb:B4DZ67|uniprotkb:Q6PJE1|intact:EBI-10966404|ensembl:ENSP00000229179 psi-mi:nu133_human(display_long)|uniprotkb:NUP133(gene name)|psi-mi:NUP133(display_short)|uniprotkb:Nucleoporin Nup133(gene name synonym)|uniprotkb:133 kDa nucleoporin(gene name synonym) psi-mi:nu107_human(display_long)|uniprotkb:NUP107(gene name)|psi-mi:NUP107(display_short)|uniprotkb:Nucleoporin Nup107(gene name synonym)|uniprotkb:107 kDa nucleoporin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zuccolo et al. (2007) pubmed:17363900|imex:IM-13993|mint:MINT-5219767 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7329388|mint:MINT-4788188|imex:IM-13993-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060700.2|ensembl:ENSG00000069248(gene)|ensembl:ENST00000261396(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0061053"(somite development)|go:"GO:0072006"(nephron development)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037624|mint:Q8WUM0|rcsb pdb:1XKS|rcsb pdb:3CQC|rcsb pdb:3CQG|rcsb pdb:3I4R|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025|mint:MINT-4788192(identity) refseq:NP_065134.1|refseq:NP_001317121.1|ensembl:ENSG00000111581(gene)|ensembl:ENST00000229179(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008585"(female gonad development)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0072006"(nephron development)|interpro:IPR007252(Nuclear pore protein 84/107)|mint:P57740|rcsb pdb:3CQC|rcsb pdb:3CQG|rcsb pdb:3I4R|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025|mint:MINT-4788189(identity) - - - figure legend:F1A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2007/05/29 2015/09/23 rogid:J89Ja9KNryxKNUd9rqNbi8EC09g9606 rogid:76eAOFdL5JLBp0giaH8nhc3BMEI9606 intact-crc:4EF177E16E54AD42|rigid:nsFF4ORP+X3MljzoZqVF9Q/pxDA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WUM0 uniprotkb:P49790 intact:EBI-295695|uniprotkb:Q5T8N0|uniprotkb:Q9H9W2|uniprotkb:Q9NV71|uniprotkb:Q9NVC4|uniprotkb:B2RAZ8|ensembl:ENSP00000261396 intact:EBI-286779|uniprotkb:Q5T9I7|intact:EBI-1237421|uniprotkb:E7EPX5|uniprotkb:Q4LE47|uniprotkb:Q7Z743|uniprotkb:B4DIK2|uniprotkb:F6QR24|ensembl:ENSP00000262077 psi-mi:nu133_human(display_long)|uniprotkb:NUP133(gene name)|psi-mi:NUP133(display_short)|uniprotkb:Nucleoporin Nup133(gene name synonym)|uniprotkb:133 kDa nucleoporin(gene name synonym) psi-mi:nu153_human(display_long)|uniprotkb:Nucleoporin Nup153(gene name synonym)|uniprotkb:153 kDa nucleoporin(gene name synonym)|uniprotkb:NUP153(gene name)|psi-mi:NUP153(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zuccolo et al. (2007) pubmed:17363900|imex:IM-13993|mint:MINT-5219767 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7329388|mint:MINT-4788188|imex:IM-13993-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060700.2|ensembl:ENSG00000069248(gene)|ensembl:ENST00000261396(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0061053"(somite development)|go:"GO:0072006"(nephron development)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037624|mint:Q8WUM0|rcsb pdb:1XKS|rcsb pdb:3CQC|rcsb pdb:3CQG|rcsb pdb:3I4R|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025|mint:MINT-4788192(identity) ensembl:ENSP00000262077|ensembl:ENST00000537253|ensembl:ENSP00000444029|ensembl:ENST00000613258|ensembl:ENSP00000478627|refseq:NP_005115.2|refseq:NP_001265138.1|refseq:NP_001265139.1|dip:DIP-38185N|ensembl:ENSG00000124789(gene)|ensembl:ENST00000262077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043657"(host cell)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046832"(negative regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR013913(Nucleoporin, Nup153-like)|interpro:IPR018892|interpro:IPR026054|interpro:IPR036443|mint:P49790|rcsb pdb:2EBQ|rcsb pdb:2EBR|rcsb pdb:2EBV|rcsb pdb:2GQE|rcsb pdb:4U0C|rcsb pdb:4U0D|rcsb pdb:5TSV|rcsb pdb:5TSX|rcsb pdb:6AYA|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|mint:MINT-4792437(identity) - - - figure legend:F1A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2007/05/29 2015/09/23 rogid:J89Ja9KNryxKNUd9rqNbi8EC09g9606 rogid:rOax/ikcAu5fmDiCOauVr7Y/fzY9606 intact-crc:4EF177E16E54AD42|rigid:nsFF4ORP+X3MljzoZqVF9Q/pxDA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)