#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9BR76	uniprotkb:Q8WYL5	intact:EBI-351152|uniprotkb:B2RD45|ensembl:ENSP00000340211|ensembl:ENSP00000377471	intact:EBI-1222387|uniprotkb:Q6P6C0|uniprotkb:Q8N9A7|uniprotkb:Q8WYL3|uniprotkb:Q8WYL4|uniprotkb:Q9P2P8|ensembl:ENSP00000315713	psi-mi:cor1b_human(display_long)|uniprotkb:CORO1B(gene name)|psi-mi:CORO1B(display_short)|uniprotkb:Coronin-2(gene name synonym)	psi-mi:ssh1_human(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:KIAA1298(gene name synonym)|uniprotkb:SSH1L(gene name synonym)|uniprotkb:SSH-like protein 1(gene name synonym)	psi-mi:"MI:0434"(phosphatase assay)	Cai et al. (2007)	imex:IM-11814|pubmed:17350576	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1222497|imex:IM-11814-7	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001018080.1|refseq:NP_065174.1|ensembl:ENSG00000172725(gene)|ensembl:ENST00000341356(transcript)|ensembl:ENST00000393893(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031529"(ruffle organization)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090135"(actin filament branching)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027340|interpro:IPR036322|mint:Q9BR76|go:"GO:0035767"(endothelial cell chemotaxis)|dip:DIP-33176N	refseq:NP_001154802.1|refseq:NP_001154803.1|refseq:NP_061857.3|refseq:XP_016874982.1|refseq:XP_016874983.1|ensembl:ENSG00000084112(gene)|ensembl:ENST00000326495(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0045202"(synapse)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR014876(DEK C terminal)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR027233|interpro:IPR029021|interpro:IPR043587|interpro:IPR043588	go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)	-	-	comment:Recombinant Coronin 1 B was expressed in Drosophila S2 cells or HEK-293 cells.|figure legend:4 C|resulting-ptm:"Coronin 1 B was dephosphorylated by Slingshot (SSH1L)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/03/27	2014/10/16	rogid:80hrtgIbLoisOZLGgfaa1TLBFMg9606	rogid:mZqVdDjzQ5MkNi3P8+Z5siioiUY9606	intact-crc:778AFAFE3CAD17BA|rigid:rckEwG1VTtDEqs1F7XqQgzFC0sY	false	O-phospho-L-serine:?-?	myc tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9BR76	uniprotkb:O15144	intact:EBI-351152|uniprotkb:B2RD45|ensembl:ENSP00000340211|ensembl:ENSP00000377471	intact:EBI-352356|uniprotkb:Q92801|uniprotkb:Q9P1D4|ensembl:ENSP00000295685|ensembl:ENSP00000327137	psi-mi:cor1b_human(display_long)|uniprotkb:CORO1B(gene name)|psi-mi:CORO1B(display_short)|uniprotkb:Coronin-2(gene name synonym)	psi-mi:arpc2_human(display_long)|uniprotkb:ARPC2(gene name)|psi-mi:ARPC2(display_short)|uniprotkb:ARC34(gene name synonym)|uniprotkb:PRO2446(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cai et al. (2007)	imex:IM-11814|pubmed:17350576	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1223040|imex:IM-11814-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001018080.1|refseq:NP_065174.1|ensembl:ENSG00000172725(gene)|ensembl:ENST00000341356(transcript)|ensembl:ENST00000393893(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031529"(ruffle organization)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090135"(actin filament branching)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027340|interpro:IPR036322|mint:Q9BR76|go:"GO:0035767"(endothelial cell chemotaxis)|dip:DIP-33176N	refseq:NP_005722.1|refseq:NP_690601.1|go:"GO:0005925"(focal adhesion)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036195"(muscle cell projection membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|mint:O15144|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|go:"GO:0005885"(Arp2/3 protein complex)|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|reactome:R-HSA-3928662|ensembl:ENSG00000163466(gene)|ensembl:ENST00000295685(transcript)|ensembl:ENST00000315717(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|dip:DIP-33197N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4 H|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/03/27	2014/10/16	rogid:80hrtgIbLoisOZLGgfaa1TLBFMg9606	rogid:v5OozQTt614rvrBBoUavbAzjgZ49606	intact-crc:258B3673EFCD11F2|rigid:IUSrn/IXyLhtWbn9LxdZQ1Ms6fY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9BR76	uniprotkb:Q8WYL5	intact:EBI-351152|uniprotkb:B2RD45|ensembl:ENSP00000340211|ensembl:ENSP00000377471	intact:EBI-1222387|uniprotkb:Q6P6C0|uniprotkb:Q8N9A7|uniprotkb:Q8WYL3|uniprotkb:Q8WYL4|uniprotkb:Q9P2P8|ensembl:ENSP00000315713	psi-mi:cor1b_human(display_long)|uniprotkb:CORO1B(gene name)|psi-mi:CORO1B(display_short)|uniprotkb:Coronin-2(gene name synonym)	psi-mi:ssh1_human(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:KIAA1298(gene name synonym)|uniprotkb:SSH1L(gene name synonym)|uniprotkb:SSH-like protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cai et al. (2007)	imex:IM-11814|pubmed:17350576	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1223040|imex:IM-11814-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001018080.1|refseq:NP_065174.1|ensembl:ENSG00000172725(gene)|ensembl:ENST00000341356(transcript)|ensembl:ENST00000393893(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031529"(ruffle organization)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090135"(actin filament branching)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027340|interpro:IPR036322|mint:Q9BR76|go:"GO:0035767"(endothelial cell chemotaxis)|dip:DIP-33176N	refseq:NP_001154802.1|refseq:NP_001154803.1|refseq:NP_061857.3|refseq:XP_016874982.1|refseq:XP_016874983.1|ensembl:ENSG00000084112(gene)|ensembl:ENST00000326495(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0045202"(synapse)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR014876(DEK C terminal)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR027233|interpro:IPR029021|interpro:IPR043587|interpro:IPR043588	psi-mi:"MI:0469"(intact)	-	-	figure legend:4 H|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/03/27	2014/10/16	rogid:80hrtgIbLoisOZLGgfaa1TLBFMg9606	rogid:mZqVdDjzQ5MkNi3P8+Z5siioiUY9606	intact-crc:258B3673EFCD11F2|rigid:IUSrn/IXyLhtWbn9LxdZQ1Ms6fY	false	-	myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O89046	uniprotkb:Q8WYL5	intact:EBI-1223069	intact:EBI-1222387|uniprotkb:Q6P6C0|uniprotkb:Q8N9A7|uniprotkb:Q8WYL3|uniprotkb:Q8WYL4|uniprotkb:Q9P2P8|ensembl:ENSP00000315713	psi-mi:cor1b_rat(display_long)|uniprotkb:Coro1b(gene name)|psi-mi:Coro1b(display_short)|uniprotkb:Coronin-2(gene name synonym)	psi-mi:ssh1_human(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:KIAA1298(gene name synonym)|uniprotkb:SSH1L(gene name synonym)|uniprotkb:SSH-like protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cai et al. (2007)	imex:IM-11814|pubmed:17350576	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1223075|imex:IM-11814-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|rgd:2382|refseq:NP_062095.1|interpro:IPR015505(Coronin)|mint:O89046|interpro:IPR027340|interpro:IPR036322|go:"GO:0001725"(stress fiber)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031529"(ruffle organization)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090135"(actin filament branching)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)	refseq:NP_001154802.1|refseq:NP_001154803.1|refseq:NP_061857.3|refseq:XP_016874982.1|refseq:XP_016874983.1|ensembl:ENSG00000084112(gene)|ensembl:ENST00000326495(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0045202"(synapse)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR014876(DEK C terminal)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR027233|interpro:IPR029021|interpro:IPR043587|interpro:IPR043588	psi-mi:"MI:0469"(intact)	-	-	figure legend:4 I|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-rat-2)|taxid:10116(Rat R2 embryo cells)	-	2007/03/27	2014/10/16	rogid:cHLzuIK3uQelgP3cXpzqD1ToGNA10116	rogid:mZqVdDjzQ5MkNi3P8+Z5siioiUY9606	intact-crc:A6D0B6150FE7A16B|rigid:AY0HgJXdqHrRM/0agZjAJ2YpTPE	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O89046	uniprotkb:P85970	intact:EBI-1223069	intact:EBI-1223150	psi-mi:cor1b_rat(display_long)|uniprotkb:Coro1b(gene name)|psi-mi:Coro1b(display_short)|uniprotkb:Coronin-2(gene name synonym)	psi-mi:arpc2_rat(display_long)|uniprotkb:Arpc2(gene name)|psi-mi:Arpc2(display_short)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cai et al. (2007)	imex:IM-11814|pubmed:17350576	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1223075|imex:IM-11814-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|rgd:2382|refseq:NP_062095.1|interpro:IPR015505(Coronin)|mint:O89046|interpro:IPR027340|interpro:IPR036322|go:"GO:0001725"(stress fiber)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031529"(ruffle organization)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090135"(actin filament branching)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)	reactome:R-RNO-5663213|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|rgd:1305848|interpro:IPR034666|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0019894"(kinesin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030141"(secretory granule)|go:"GO:0030426"(growth cone)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031941"(filamentous actin)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034021"(response to silicon dioxide)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035650"(AP-1 adaptor complex binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0036195"(muscle cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0051015"(actin filament binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0061825"(podosome core)|go:"GO:0061826"(podosome ring)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0061834"(actin filament branch point)|go:"GO:0061835"(ventral surface of cell)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090725"(peripheral region of growth cone)|go:"GO:0097440"(apical dendrite)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000814"(positive regulation of barbed-end actin filament capping)|reactome:R-RNO-2029482|reactome:R-RNO-3928662|reactome:R-RNO-8856828	psi-mi:"MI:0469"(intact)	-	-	figure legend:4 I|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-rat-2)|taxid:10116(Rat R2 embryo cells)	-	2007/03/27	2014/10/16	rogid:cHLzuIK3uQelgP3cXpzqD1ToGNA10116	rogid:btMZRS12WGW/Bm3iHleBFvmF+i010116	intact-crc:A6D0B6150FE7A16B|rigid:AY0HgJXdqHrRM/0agZjAJ2YpTPE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P85970	uniprotkb:Q8WYL5	intact:EBI-1223150	intact:EBI-1222387|uniprotkb:Q6P6C0|uniprotkb:Q8N9A7|uniprotkb:Q8WYL3|uniprotkb:Q8WYL4|uniprotkb:Q9P2P8|ensembl:ENSP00000315713	psi-mi:arpc2_rat(display_long)|uniprotkb:Arpc2(gene name)|psi-mi:Arpc2(display_short)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym)	psi-mi:ssh1_human(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:KIAA1298(gene name synonym)|uniprotkb:SSH1L(gene name synonym)|uniprotkb:SSH-like protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cai et al. (2007)	imex:IM-11814|pubmed:17350576	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1223181|imex:IM-11814-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-RNO-5663213|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|rgd:1305848|interpro:IPR034666|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0019894"(kinesin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030141"(secretory granule)|go:"GO:0030426"(growth cone)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031941"(filamentous actin)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034021"(response to silicon dioxide)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035650"(AP-1 adaptor complex binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0036195"(muscle cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0051015"(actin filament binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0061825"(podosome core)|go:"GO:0061826"(podosome ring)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0061834"(actin filament branch point)|go:"GO:0061835"(ventral surface of cell)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090725"(peripheral region of growth cone)|go:"GO:0097440"(apical dendrite)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000814"(positive regulation of barbed-end actin filament capping)|reactome:R-RNO-2029482|reactome:R-RNO-3928662|reactome:R-RNO-8856828	refseq:NP_001154802.1|refseq:NP_001154803.1|refseq:NP_061857.3|refseq:XP_016874982.1|refseq:XP_016874983.1|ensembl:ENSG00000084112(gene)|ensembl:ENST00000326495(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0045202"(synapse)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR014876(DEK C terminal)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR027233|interpro:IPR029021|interpro:IPR043587|interpro:IPR043588	psi-mi:"MI:0469"(intact)	-	-	figure legend:4 J|stimulant:These interactions do not occur in Coronin 1B-depleted cells.|comment:"The evidence suggests SSH1L, Coronin 1B and Arp2/3 (as reported by p34Arc) exist in a ternary complex, bridged by Coronin 1B."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-rat-2)|taxid:10116(Rat R2 embryo cells)	-	2007/03/27	2014/10/16	rogid:btMZRS12WGW/Bm3iHleBFvmF+i010116	rogid:mZqVdDjzQ5MkNi3P8+Z5siioiUY9606	intact-crc:DE49CD47BC5CA11D|rigid:AY0HgJXdqHrRM/0agZjAJ2YpTPE	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P85970	uniprotkb:O89046	intact:EBI-1223150	intact:EBI-1223069	psi-mi:arpc2_rat(display_long)|uniprotkb:Arpc2(gene name)|psi-mi:Arpc2(display_short)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym)	psi-mi:cor1b_rat(display_long)|uniprotkb:Coro1b(gene name)|psi-mi:Coro1b(display_short)|uniprotkb:Coronin-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Cai et al. (2007)	imex:IM-11814|pubmed:17350576	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1223181|imex:IM-11814-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-RNO-5663213|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|rgd:1305848|interpro:IPR034666|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0019894"(kinesin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030141"(secretory granule)|go:"GO:0030426"(growth cone)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031941"(filamentous actin)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034021"(response to silicon dioxide)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035650"(AP-1 adaptor complex binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0036195"(muscle cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0051015"(actin filament binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0061825"(podosome core)|go:"GO:0061826"(podosome ring)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0061834"(actin filament branch point)|go:"GO:0061835"(ventral surface of cell)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090725"(peripheral region of growth cone)|go:"GO:0097440"(apical dendrite)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000814"(positive regulation of barbed-end actin filament capping)|reactome:R-RNO-2029482|reactome:R-RNO-3928662|reactome:R-RNO-8856828	interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|rgd:2382|refseq:NP_062095.1|interpro:IPR015505(Coronin)|mint:O89046|interpro:IPR027340|interpro:IPR036322|go:"GO:0001725"(stress fiber)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031529"(ruffle organization)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090135"(actin filament branching)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4 J|stimulant:These interactions do not occur in Coronin 1B-depleted cells.|comment:"The evidence suggests SSH1L, Coronin 1B and Arp2/3 (as reported by p34Arc) exist in a ternary complex, bridged by Coronin 1B."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-rat-2)|taxid:10116(Rat R2 embryo cells)	-	2007/03/27	2014/10/16	rogid:btMZRS12WGW/Bm3iHleBFvmF+i010116	rogid:cHLzuIK3uQelgP3cXpzqD1ToGNA10116	intact-crc:DE49CD47BC5CA11D|rigid:AY0HgJXdqHrRM/0agZjAJ2YpTPE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8WYL5	uniprotkb:P85970	intact:EBI-1222387|uniprotkb:Q6P6C0|uniprotkb:Q8N9A7|uniprotkb:Q8WYL3|uniprotkb:Q8WYL4|uniprotkb:Q9P2P8|ensembl:ENSP00000315713	intact:EBI-1223150	psi-mi:ssh1_human(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:KIAA1298(gene name synonym)|uniprotkb:SSH1L(gene name synonym)|uniprotkb:SSH-like protein 1(gene name synonym)	psi-mi:arpc2_rat(display_long)|uniprotkb:Arpc2(gene name)|psi-mi:Arpc2(display_short)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cai et al. (2007)	imex:IM-11814|pubmed:17350576	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1223093|imex:IM-11814-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001154802.1|refseq:NP_001154803.1|refseq:NP_061857.3|refseq:XP_016874982.1|refseq:XP_016874983.1|ensembl:ENSG00000084112(gene)|ensembl:ENST00000326495(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0045202"(synapse)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR014876(DEK C terminal)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR027233|interpro:IPR029021|interpro:IPR043587|interpro:IPR043588	reactome:R-RNO-5663213|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|rgd:1305848|interpro:IPR034666|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0019894"(kinesin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030141"(secretory granule)|go:"GO:0030426"(growth cone)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031941"(filamentous actin)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034021"(response to silicon dioxide)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035650"(AP-1 adaptor complex binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0036195"(muscle cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0051015"(actin filament binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0061825"(podosome core)|go:"GO:0061826"(podosome ring)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0061834"(actin filament branch point)|go:"GO:0061835"(ventral surface of cell)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090725"(peripheral region of growth cone)|go:"GO:0097440"(apical dendrite)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000814"(positive regulation of barbed-end actin filament capping)|reactome:R-RNO-2029482|reactome:R-RNO-3928662|reactome:R-RNO-8856828	psi-mi:"MI:0469"(intact)	-	-	figure legend:4 I|stimulant:These interactions did not occur after Coronin 1B was immunodepleted from the cell lysate.|comment:"The evidence suggests Coronin 1B, SSH1L, and Arp2/3 (as reported by the p34 subunit) exist in a ternary complex, bridged by Coronin 1B."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-rat-2)|taxid:10116(Rat R2 embryo cells)	-	2007/03/27	2014/10/16	rogid:mZqVdDjzQ5MkNi3P8+Z5siioiUY9606	rogid:btMZRS12WGW/Bm3iHleBFvmF+i010116	intact-crc:AE21F4644CFA9725|rigid:AY0HgJXdqHrRM/0agZjAJ2YpTPE	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8WYL5	uniprotkb:O89046	intact:EBI-1222387|uniprotkb:Q6P6C0|uniprotkb:Q8N9A7|uniprotkb:Q8WYL3|uniprotkb:Q8WYL4|uniprotkb:Q9P2P8|ensembl:ENSP00000315713	intact:EBI-1223069	psi-mi:ssh1_human(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:KIAA1298(gene name synonym)|uniprotkb:SSH1L(gene name synonym)|uniprotkb:SSH-like protein 1(gene name synonym)	psi-mi:cor1b_rat(display_long)|uniprotkb:Coro1b(gene name)|psi-mi:Coro1b(display_short)|uniprotkb:Coronin-2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cai et al. (2007)	imex:IM-11814|pubmed:17350576	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1223093|imex:IM-11814-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001154802.1|refseq:NP_001154803.1|refseq:NP_061857.3|refseq:XP_016874982.1|refseq:XP_016874983.1|ensembl:ENSG00000084112(gene)|ensembl:ENST00000326495(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0045202"(synapse)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR014876(DEK C terminal)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR027233|interpro:IPR029021|interpro:IPR043587|interpro:IPR043588	interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|rgd:2382|refseq:NP_062095.1|interpro:IPR015505(Coronin)|mint:O89046|interpro:IPR027340|interpro:IPR036322|go:"GO:0001725"(stress fiber)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031529"(ruffle organization)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090135"(actin filament branching)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:2000393"(negative regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)	psi-mi:"MI:0469"(intact)	-	-	figure legend:4 I|stimulant:These interactions did not occur after Coronin 1B was immunodepleted from the cell lysate.|comment:"The evidence suggests Coronin 1B, SSH1L, and Arp2/3 (as reported by the p34 subunit) exist in a ternary complex, bridged by Coronin 1B."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-rat-2)|taxid:10116(Rat R2 embryo cells)	-	2007/03/27	2014/10/16	rogid:mZqVdDjzQ5MkNi3P8+Z5siioiUY9606	rogid:cHLzuIK3uQelgP3cXpzqD1ToGNA10116	intact-crc:AE21F4644CFA9725|rigid:AY0HgJXdqHrRM/0agZjAJ2YpTPE	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8WYL5	uniprotkb:O15144	intact:EBI-1222387|uniprotkb:Q6P6C0|uniprotkb:Q8N9A7|uniprotkb:Q8WYL3|uniprotkb:Q8WYL4|uniprotkb:Q9P2P8|ensembl:ENSP00000315713	intact:EBI-352356|uniprotkb:Q92801|uniprotkb:Q9P1D4|ensembl:ENSP00000295685|ensembl:ENSP00000327137	psi-mi:ssh1_human(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:KIAA1298(gene name synonym)|uniprotkb:SSH1L(gene name synonym)|uniprotkb:SSH-like protein 1(gene name synonym)	psi-mi:arpc2_human(display_long)|uniprotkb:ARPC2(gene name)|psi-mi:ARPC2(display_short)|uniprotkb:ARC34(gene name synonym)|uniprotkb:PRO2446(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cai et al. (2007)	imex:IM-11814|pubmed:17350576	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1223050|imex:IM-11814-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001154802.1|refseq:NP_001154803.1|refseq:NP_061857.3|refseq:XP_016874982.1|refseq:XP_016874983.1|ensembl:ENSG00000084112(gene)|ensembl:ENST00000326495(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0045202"(synapse)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR014876(DEK C terminal)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR027233|interpro:IPR029021|interpro:IPR043587|interpro:IPR043588	refseq:NP_005722.1|refseq:NP_690601.1|go:"GO:0005925"(focal adhesion)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036195"(muscle cell projection membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|mint:O15144|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|go:"GO:0005885"(Arp2/3 protein complex)|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|reactome:R-HSA-3928662|ensembl:ENSG00000163466(gene)|ensembl:ENST00000295685(transcript)|ensembl:ENST00000315717(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|dip:DIP-33197N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4 H|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/03/27	2014/10/16	rogid:mZqVdDjzQ5MkNi3P8+Z5siioiUY9606	rogid:v5OozQTt614rvrBBoUavbAzjgZ49606	intact-crc:9D436C1C3BAD51D3|rigid:IUSrn/IXyLhtWbn9LxdZQ1Ms6fY	false	myc tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8WYL5	uniprotkb:Q9BR76	intact:EBI-1222387|uniprotkb:Q6P6C0|uniprotkb:Q8N9A7|uniprotkb:Q8WYL3|uniprotkb:Q8WYL4|uniprotkb:Q9P2P8|ensembl:ENSP00000315713	intact:EBI-351152|uniprotkb:B2RD45|ensembl:ENSP00000340211|ensembl:ENSP00000377471	psi-mi:ssh1_human(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:KIAA1298(gene name synonym)|uniprotkb:SSH1L(gene name synonym)|uniprotkb:SSH-like protein 1(gene name synonym)	psi-mi:cor1b_human(display_long)|uniprotkb:CORO1B(gene name)|psi-mi:CORO1B(display_short)|uniprotkb:Coronin-2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cai et al. (2007)	imex:IM-11814|pubmed:17350576	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1223050|imex:IM-11814-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001154802.1|refseq:NP_001154803.1|refseq:NP_061857.3|refseq:XP_016874982.1|refseq:XP_016874983.1|ensembl:ENSG00000084112(gene)|ensembl:ENST00000326495(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0045202"(synapse)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR014876(DEK C terminal)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR027233|interpro:IPR029021|interpro:IPR043587|interpro:IPR043588	refseq:NP_001018080.1|refseq:NP_065174.1|ensembl:ENSG00000172725(gene)|ensembl:ENST00000341356(transcript)|ensembl:ENST00000393893(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031529"(ruffle organization)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090135"(actin filament branching)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027340|interpro:IPR036322|mint:Q9BR76|go:"GO:0035767"(endothelial cell chemotaxis)|dip:DIP-33176N	psi-mi:"MI:0469"(intact)	-	-	figure legend:4 H|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/03/27	2014/10/16	rogid:mZqVdDjzQ5MkNi3P8+Z5siioiUY9606	rogid:80hrtgIbLoisOZLGgfaa1TLBFMg9606	intact-crc:9D436C1C3BAD51D3|rigid:IUSrn/IXyLhtWbn9LxdZQ1Ms6fY	false	myc tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9BR76	uniprotkb:O15144	intact:EBI-351152|uniprotkb:B2RD45|ensembl:ENSP00000340211|ensembl:ENSP00000377471	intact:EBI-352356|uniprotkb:Q92801|uniprotkb:Q9P1D4|ensembl:ENSP00000295685|ensembl:ENSP00000327137	psi-mi:cor1b_human(display_long)|uniprotkb:CORO1B(gene name)|psi-mi:CORO1B(display_short)|uniprotkb:Coronin-2(gene name synonym)	psi-mi:arpc2_human(display_long)|uniprotkb:ARPC2(gene name)|psi-mi:ARPC2(display_short)|uniprotkb:ARC34(gene name synonym)|uniprotkb:PRO2446(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Cai et al. (2007)	imex:IM-11814|pubmed:17350576	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1225414|imex:IM-11814-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001018080.1|refseq:NP_065174.1|ensembl:ENSG00000172725(gene)|ensembl:ENST00000341356(transcript)|ensembl:ENST00000393893(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031529"(ruffle organization)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090135"(actin filament branching)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027340|interpro:IPR036322|mint:Q9BR76|go:"GO:0035767"(endothelial cell chemotaxis)|dip:DIP-33176N	refseq:NP_005722.1|refseq:NP_690601.1|go:"GO:0005925"(focal adhesion)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036195"(muscle cell projection membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|mint:O15144|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|go:"GO:0005885"(Arp2/3 protein complex)|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|reactome:R-HSA-3928662|ensembl:ENSG00000163466(gene)|ensembl:ENST00000295685(transcript)|ensembl:ENST00000315717(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|dip:DIP-33197N	psi-mi:"MI:0469"(intact)	-	-	figure legend:3 C|comment:The Arp2/3 complex is reported by p34Arc.|comment:Recombinant Coronin 1 B is expressed in Drosphila S2 cells or HEK293 cells.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/03/27	2014/10/16	rogid:80hrtgIbLoisOZLGgfaa1TLBFMg9606	rogid:v5OozQTt614rvrBBoUavbAzjgZ49606	intact-crc:BE206C623D0D17BC|rigid:zfGMNwevAD6PMvOh4xwUIZiWdSs	false	his tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)