#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P68432	uniprotkb:P41229	intact:EBI-79764|ensembl:ENSBTAP00000059273|ensembl:ENSBTAP00000061745|ensembl:ENSBTAP00000061853|ensembl:ENSBTAP00000070745|ensembl:ENSBTAP00000071787|ensembl:ENSBTAP00000074529|uniprotkb:P02295|uniprotkb:P02296|uniprotkb:P16106	intact:EBI-1246541|uniprotkb:B4E3I2|uniprotkb:F5H3T1|ensembl:ENSP00000364550|uniprotkb:Q5JUX3|uniprotkb:Q5JUX4|uniprotkb:Q5JUX5|uniprotkb:Q7Z5S5|uniprotkb:B0QZ44|intact:EBI-28983825	psi-mi:h31_bovin(display_long)	psi-mi:kdm5c_human(display_long)|uniprotkb:KDM5C(gene name)|psi-mi:KDM5C(display_short)|uniprotkb:DXS1272E(gene name synonym)|uniprotkb:SMCX(gene name synonym)|uniprotkb:XE169(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1C(gene name synonym)|uniprotkb:Protein SmcX(gene name synonym)|uniprotkb:Protein Xe169(gene name synonym)|uniprotkb:JARID1C(gene name synonym)|uniprotkb:Histone demethylase JARID1C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5C"(gene name synonym)	psi-mi:"MI:0870"(demethylase assay)	Iwase et al. (2007)	imex:IM-11878|pubmed:17320160	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0871"(demethylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1246588|imex:IM-11878-1	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSBTAT00000071248(transcript)|ensembl:ENSBTAT00000080858(transcript)|ensembl:ENSBTAT00000069848(transcript)|ensembl:ENSBTAT00000083013(transcript)|ensembl:ENSBTAT00000085851(transcript)|ensembl:ENSBTAT00000087179(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-BTA-1266695|reactome:R-BTA-201722|reactome:R-BTA-212300|reactome:R-BTA-2299718|reactome:R-BTA-2559580|reactome:R-BTA-3214815|reactome:R-BTA-3214841|reactome:R-BTA-3214842|reactome:R-BTA-3214847|reactome:R-BTA-3214858|reactome:R-BTA-3247509|reactome:R-BTA-427359|reactome:R-BTA-427413|reactome:R-BTA-5250924|reactome:R-BTA-73728|reactome:R-BTA-8936459|reactome:R-BTA-9018519|reactome:R-BTA-983231|ensembl:ENSBTAG00000048478(gene)|ensembl:ENSBTAG00000048666(gene)|ensembl:ENSBTAG00000050102(gene)|ensembl:ENSBTAG00000050209(gene)|ensembl:ENSBTAG00000050477(gene)|ensembl:ENSBTAG00000054582(gene)|refseq:XP_002697506.1|refseq:XP_002697575.1|refseq:XP_874006.1|refseq:XP_015324502.1|refseq:XP_015315463.1|refseq:XP_015324501.1|refseq:XP_005196706.1|refseq:XP_005223855.1|refseq:XP_010823755.1|refseq:XP_010816767.1	refseq:NP_001140174.1|refseq:NP_004178.2|refseq:NP_001269551.1|ensembl:ENSG00000126012(gene)|ensembl:ENST00000375401(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|refseq:XP_011529128.1|ensembl:ENST00000375379|ensembl:ENSP00000364528|ensembl:ENST00000375383|ensembl:ENSP00000364532|ensembl:ENSP00000364550|ensembl:ENST00000404049|ensembl:ENSP00000385394|ensembl:ENST00000452825|ensembl:ENSP00000445176|refseq:XP_005262092.1|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P41229|rcsb pdb:2JRZ|rcsb pdb:5FWJ|reactome:R-HSA-3214842|dip:DIP-39663N	go:"GO:0016577"(histone demethylation)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)	-	-	figure legend:2|resulting-ptm:Mono-methyl Lysine 4|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/04/20	2014/10/16	rogid:ood0OohxZHuhsWZtO7U7GMc+LwM9913	rogid:sBtK/VaMcyTMcinoqnOqwBdl7TM9606	intact-crc:1F8D1BD435C8629F|rigid:P5kF6rUF9PJi1C65TC61/liw7to	false	N6,N6-dimethyl-L-lysine:4-4|N6,N6,N6-trimethyl-L-lysine:4-4	flag tag:?-?	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P68432	uniprotkb:Q9BY66	intact:EBI-79764|ensembl:ENSBTAP00000059273|ensembl:ENSBTAP00000061745|ensembl:ENSBTAP00000061853|ensembl:ENSBTAP00000070745|ensembl:ENSBTAP00000071787|ensembl:ENSBTAP00000074529|uniprotkb:P02295|uniprotkb:P02296|uniprotkb:P16106	intact:EBI-1246860|uniprotkb:B7ZLX1|uniprotkb:A2RU19|uniprotkb:Q92509|uniprotkb:Q92809|uniprotkb:Q9HCU1|uniprotkb:A6H8V7|intact:EBI-28984693|ensembl:ENSP00000322408	psi-mi:h31_bovin(display_long)	psi-mi:kdm5d_human(display_long)|uniprotkb:KDM5D(gene name)|psi-mi:KDM5D(display_short)|uniprotkb:HY(gene name synonym)|uniprotkb:HYA(gene name synonym)|uniprotkb:KIAA0234(gene name synonym)|uniprotkb:SMCY(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1D(gene name synonym)|uniprotkb:Protein SmcY(gene name synonym)|uniprotkb:Histocompatibility Y antigen(gene name synonym)|uniprotkb:JARID1D(gene name synonym)|uniprotkb:Histone demethylase JARID1D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5D"(gene name synonym)	psi-mi:"MI:0870"(demethylase assay)	Iwase et al. (2007)	imex:IM-11878|pubmed:17320160	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0871"(demethylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1246892|imex:IM-11878-3	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSBTAT00000071248(transcript)|ensembl:ENSBTAT00000080858(transcript)|ensembl:ENSBTAT00000069848(transcript)|ensembl:ENSBTAT00000083013(transcript)|ensembl:ENSBTAT00000085851(transcript)|ensembl:ENSBTAT00000087179(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-BTA-1266695|reactome:R-BTA-201722|reactome:R-BTA-212300|reactome:R-BTA-2299718|reactome:R-BTA-2559580|reactome:R-BTA-3214815|reactome:R-BTA-3214841|reactome:R-BTA-3214842|reactome:R-BTA-3214847|reactome:R-BTA-3214858|reactome:R-BTA-3247509|reactome:R-BTA-427359|reactome:R-BTA-427413|reactome:R-BTA-5250924|reactome:R-BTA-73728|reactome:R-BTA-8936459|reactome:R-BTA-9018519|reactome:R-BTA-983231|ensembl:ENSBTAG00000048478(gene)|ensembl:ENSBTAG00000048666(gene)|ensembl:ENSBTAG00000050102(gene)|ensembl:ENSBTAG00000050209(gene)|ensembl:ENSBTAG00000050477(gene)|ensembl:ENSBTAG00000054582(gene)|refseq:XP_002697506.1|refseq:XP_002697575.1|refseq:XP_874006.1|refseq:XP_015324502.1|refseq:XP_015315463.1|refseq:XP_015324501.1|refseq:XP_005196706.1|refseq:XP_005223855.1|refseq:XP_010823755.1|refseq:XP_010816767.1	refseq:NP_001140177.1|refseq:NP_001140178.1|refseq:NP_004644.2|ensembl:ENST00000382806|ensembl:ENSP00000372256|ensembl:ENST00000541639|ensembl:ENSP00000322408|ensembl:ENSP00000444293|ensembl:ENSG00000012817(gene)|ensembl:ENST00000317961(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0002457"(T cell antigen processing and presentation)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|rcsb pdb:2E6R|rcsb pdb:2YQE|reactome:R-HSA-3214842	go:"GO:0016577"(histone demethylation)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)	-	-	figure legend:2|resulting-ptm:Mono-mehtyl lysine 4|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/04/20	2014/10/16	rogid:ood0OohxZHuhsWZtO7U7GMc+LwM9913	rogid:AE6AY8YQlMdzblUWEdzVEvYpLkM9606	intact-crc:BCC2C0CAFED6E1FE|rigid:dDHAPJW2K2fkfZ/Tg0i16EzEvvA	false	N6,N6-dimethyl-L-lysine:4-4|N6,N6,N6-trimethyl-L-lysine:4-4	flag tag:?-?	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q80Y84	uniprotkb:P68432	intact:EBI-1249551|uniprotkb:Q5DTR9|uniprotkb:Q8BLU1|uniprotkb:Q8JZL8|ensembl:ENSMUSP00000038138	intact:EBI-79764|ensembl:ENSBTAP00000059273|ensembl:ENSBTAP00000061745|ensembl:ENSBTAP00000061853|ensembl:ENSBTAP00000070745|ensembl:ENSBTAP00000071787|ensembl:ENSBTAP00000074529|uniprotkb:P02295|uniprotkb:P02296|uniprotkb:P16106	psi-mi:kdm5b_mouse(display_long)|uniprotkb:Kdm5b(gene name)|psi-mi:Kdm5b(display_short)|uniprotkb:Kiaa4034(gene name synonym)|uniprotkb:Plu1(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Jarid1b(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym)	psi-mi:h31_bovin(display_long)	psi-mi:"MI:0870"(demethylase assay)	Iwase et al. (2007)	imex:IM-11878|pubmed:17320160	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0871"(demethylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1246920|imex:IM-11878-2	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_690855.2|ensembl:ENSMUSG00000042207(gene)|ensembl:ENSMUST00000047714(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|rcsb pdb:2EQY|reactome:R-MMU-3214842|reactome:R-MMU-8866911|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)	ensembl:ENSBTAT00000071248(transcript)|ensembl:ENSBTAT00000080858(transcript)|ensembl:ENSBTAT00000069848(transcript)|ensembl:ENSBTAT00000083013(transcript)|ensembl:ENSBTAT00000085851(transcript)|ensembl:ENSBTAT00000087179(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-BTA-1266695|reactome:R-BTA-201722|reactome:R-BTA-212300|reactome:R-BTA-2299718|reactome:R-BTA-2559580|reactome:R-BTA-3214815|reactome:R-BTA-3214841|reactome:R-BTA-3214842|reactome:R-BTA-3214847|reactome:R-BTA-3214858|reactome:R-BTA-3247509|reactome:R-BTA-427359|reactome:R-BTA-427413|reactome:R-BTA-5250924|reactome:R-BTA-73728|reactome:R-BTA-8936459|reactome:R-BTA-9018519|reactome:R-BTA-983231|ensembl:ENSBTAG00000048478(gene)|ensembl:ENSBTAG00000048666(gene)|ensembl:ENSBTAG00000050102(gene)|ensembl:ENSBTAG00000050209(gene)|ensembl:ENSBTAG00000050477(gene)|ensembl:ENSBTAG00000054582(gene)|refseq:XP_002697506.1|refseq:XP_002697575.1|refseq:XP_874006.1|refseq:XP_015324502.1|refseq:XP_015315463.1|refseq:XP_015324501.1|refseq:XP_005196706.1|refseq:XP_005223855.1|refseq:XP_010823755.1|refseq:XP_010816767.1	go:"GO:0016577"(histone demethylation)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)	-	-	figure legend:2|resulting-ptm:Un methylated Lysine 4.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/04/20	2014/10/16	rogid:x4PJb2DBgRIFooZ1NiH2f77YHnQ10090	rogid:ood0OohxZHuhsWZtO7U7GMc+LwM9913	intact-crc:C7708E79B6B0834D|rigid:SJCdfkAhDFJw9BGFMXsKAyccMTw	false	flag tag:?-?	N6,N6-dimethyl-L-lysine:4-4|N6,N6,N6-trimethyl-L-lysine:4-4|N6-methyl-L-lysine:4-4	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)