#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O43157	uniprotkb:Q9H3S1	intact:EBI-1111488|uniprotkb:Q6NY20|uniprotkb:Q9UIV7|uniprotkb:Q9UJ92|uniprotkb:Q9UJ93|uniprotkb:A6H8Y2|ensembl:ENSP00000296440|ensembl:ENSP00000351338	intact:EBI-3924922|uniprotkb:B3KR76|uniprotkb:Q5TCJ6|uniprotkb:B2RDH8|uniprotkb:Q8WUA9|uniprotkb:Q5TCI5|ensembl:ENSP00000347117|ensembl:ENSP00000357265|ensembl:ENSP00000357268	psi-mi:plxb1_human(display_long)|uniprotkb:PLXNB1(gene name)|psi-mi:PLXNB1(display_short)|uniprotkb:KIAA0407(gene name synonym)|uniprotkb:SEP(gene name synonym)|uniprotkb:Semaphorin receptor SEP(gene name synonym)|uniprotkb:PLXN5(gene name synonym)	psi-mi:sem4a_human(display_long)|uniprotkb:SEMA4A(gene name)|psi-mi:SEMA4A(display_short)|uniprotkb:SEMAB(gene name synonym)|uniprotkb:SEMB(gene name synonym)|uniprotkb:Semaphorin-B(gene name synonym)|uniprotkb:UNQ783/PRO1317(orf name)	psi-mi:"MI:0030"(cross-linking study)	Toyofuku et al. (2007)	pubmed:17318185|imex:IM-11385|mint:MINT-5219684	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7283629|mint:MINT-4507855|imex:IM-11385-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:2JPH|rcsb pdb:2OS6|rcsb pdb:2R2O|rcsb pdb:2REX|rcsb pdb:3HM6|rcsb pdb:3OL2|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:5B4W|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|refseq:NP_001123554.1|refseq:NP_002664.2|ensembl:ENSG00000164050(gene)|ensembl:ENST00000296440(transcript)|ensembl:ENST00000358536(transcript)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016477"(cell migration)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1900220"(semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|go:"GO:1904862"(inhibitory synapse assembly)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|mint:O43157|refseq:XP_016862120.1|dip:DIP-36742N|mint:MINT-4507857(identity)	refseq:XP_011508174.1|refseq:XP_011508175.1|refseq:NP_001180229.1|refseq:NP_001180230.1|refseq:NP_001180231.1|refseq:NP_071762.2|ensembl:ENSG00000196189(gene)|ensembl:ENST00000355014(transcript)|ensembl:ENST00000368282(transcript)|ensembl:ENST00000368285(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:1904891"(positive regulation of excitatory synapse assembly)|go:"GO:1905704"(positive regulation of inhibitory synapse assembly)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036352|mint:Q9H3S1|reactome:R-HSA-416700|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|refseq:XP_016857545.1|mint:MINT-4507856(identity)	-	-	-	figure legend:F5C|figure legend:F4B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/03/26	2014/10/16	rogid:wWC3lipQ3PIBCvCjt5t2gQTAXro9606	rogid:mET6IfHJaauZpacRiDhcsm/uDTw9606	intact-crc:72DE1EACEE30273E|rigid:MyutYCcQeT955yfkcW0AW0mXtR0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H3S1	uniprotkb:Q9ULL4	intact:EBI-3924922|uniprotkb:B3KR76|uniprotkb:Q5TCJ6|uniprotkb:B2RDH8|uniprotkb:Q8WUA9|uniprotkb:Q5TCI5|ensembl:ENSP00000347117|ensembl:ENSP00000357265|ensembl:ENSP00000357268	intact:EBI-311073|uniprotkb:Q9HDA4|ensembl:ENSP00000355378|uniprotkb:B7Z3E6|uniprotkb:F5H773	psi-mi:sem4a_human(display_long)|uniprotkb:SEMA4A(gene name)|psi-mi:SEMA4A(display_short)|uniprotkb:SEMAB(gene name synonym)|uniprotkb:SEMB(gene name synonym)|uniprotkb:Semaphorin-B(gene name synonym)|uniprotkb:UNQ783/PRO1317(orf name)	psi-mi:plxb3_human(display_long)|uniprotkb:PLXNB3(gene name)|psi-mi:PLXNB3(display_short)|uniprotkb:KIAA1206(gene name synonym)|uniprotkb:PLXN6(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Toyofuku et al. (2007)	pubmed:17318185|imex:IM-11385|mint:MINT-5219684	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7283669|mint:MINT-4507872|imex:IM-11385-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508174.1|refseq:XP_011508175.1|refseq:NP_001180229.1|refseq:NP_001180230.1|refseq:NP_001180231.1|refseq:NP_071762.2|ensembl:ENSG00000196189(gene)|ensembl:ENST00000355014(transcript)|ensembl:ENST00000368282(transcript)|ensembl:ENST00000368285(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:1904891"(positive regulation of excitatory synapse assembly)|go:"GO:1905704"(positive regulation of inhibitory synapse assembly)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036352|mint:Q9H3S1|reactome:R-HSA-416700|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|refseq:XP_016857545.1|mint:MINT-4507875(identity)	refseq:NP_001156729.1|refseq:NP_005384.2|ensembl:ENSG00000198753(gene)|ensembl:ENST00000361971(transcript)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|mint:Q9ULL4|reactome:R-HSA-416700|mint:MINT-4507873(identity)	-	-	-	figure legend:F5C|figure legend:F4B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/03/26	2014/10/16	rogid:mET6IfHJaauZpacRiDhcsm/uDTw9606	rogid:U75MXqkr8OX6OqStqcb7EPs+gNU9606	intact-crc:8469CBE522E0C104|rigid:mKz0xqry3/YXL/IPhIZ0XR9qoRQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H3S1	uniprotkb:O15031	intact:EBI-3924922|uniprotkb:B3KR76|uniprotkb:Q5TCJ6|uniprotkb:B2RDH8|uniprotkb:Q8WUA9|uniprotkb:Q5TCI5|ensembl:ENSP00000347117|ensembl:ENSP00000357265|ensembl:ENSP00000357268	intact:EBI-722004|uniprotkb:Q7KZU3|uniprotkb:Q9BSU7|uniprotkb:A6QRH0|ensembl:ENSP00000352288|ensembl:ENSP00000409171	psi-mi:sem4a_human(display_long)|uniprotkb:SEMA4A(gene name)|psi-mi:SEMA4A(display_short)|uniprotkb:SEMAB(gene name synonym)|uniprotkb:SEMB(gene name synonym)|uniprotkb:Semaphorin-B(gene name synonym)|uniprotkb:UNQ783/PRO1317(orf name)	psi-mi:plxb2_human(display_long)|uniprotkb:MM1(gene name synonym)|uniprotkb:PLXNB2(gene name)|psi-mi:PLXNB2(display_short)|uniprotkb:KIAA0315(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Toyofuku et al. (2007)	pubmed:17318185|imex:IM-11385|mint:MINT-5219684	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7283657|mint:MINT-4507865|imex:IM-11385-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508174.1|refseq:XP_011508175.1|refseq:NP_001180229.1|refseq:NP_001180230.1|refseq:NP_001180231.1|refseq:NP_071762.2|ensembl:ENSG00000196189(gene)|ensembl:ENST00000355014(transcript)|ensembl:ENST00000368282(transcript)|ensembl:ENST00000368285(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:1904891"(positive regulation of excitatory synapse assembly)|go:"GO:1905704"(positive regulation of inhibitory synapse assembly)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036352|mint:Q9H3S1|reactome:R-HSA-416700|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|refseq:XP_016857545.1|mint:MINT-4507866(identity)	refseq:NP_036533.2|ensembl:ENSG00000196576(gene)|ensembl:ENST00000359337(transcript)|ensembl:ENST00000449103(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007420"(brain development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|refseq:XP_005261966.1|refseq:XP_005261967.1|refseq:XP_005261968.1|refseq:XP_006724476.1|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0017154"(semaphorin receptor activity)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0043087"(regulation of GTPase activity)|refseq:XP_016884192.1|refseq:XP_016884193.1|go:"GO:0045727"(positive regulation of translation)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|mint:O15031|rcsb pdb:4E71|mint:MINT-4507868(identity)	-	-	-	figure legend:F5C|figure legend:F4B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/03/26	2014/10/16	rogid:mET6IfHJaauZpacRiDhcsm/uDTw9606	rogid:vUQ49+gukzUJkXbZKmcztEequc49606	intact-crc:18D69F1920B3E789|rigid:sVlNkzqyf100ouhNZ5vKdcl8iwk	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y4D7	uniprotkb:Q9H3S1	intact:EBI-310731|ensembl:ENSP00000317128|uniprotkb:Q6PJS9|uniprotkb:Q8IZJ2|uniprotkb:Q9BTQ2|uniprotkb:A7E2C6|uniprotkb:C9JPZ6	intact:EBI-3924922|uniprotkb:B3KR76|uniprotkb:Q5TCJ6|uniprotkb:B2RDH8|uniprotkb:Q8WUA9|uniprotkb:Q5TCI5|ensembl:ENSP00000347117|ensembl:ENSP00000357265|ensembl:ENSP00000357268	psi-mi:plxd1_human(display_long)|uniprotkb:PLXND1(gene name)|psi-mi:PLXND1(display_short)|uniprotkb:KIAA0620(gene name synonym)	psi-mi:sem4a_human(display_long)|uniprotkb:SEMA4A(gene name)|psi-mi:SEMA4A(display_short)|uniprotkb:SEMAB(gene name synonym)|uniprotkb:SEMB(gene name synonym)|uniprotkb:Semaphorin-B(gene name synonym)|uniprotkb:UNQ783/PRO1317(orf name)	psi-mi:"MI:0030"(cross-linking study)	Toyofuku et al. (2007)	pubmed:17318185|imex:IM-11385|mint:MINT-5219684	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7283681|mint:MINT-4507879|imex:IM-11385-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000004399(gene)|ensembl:ENST00000324093(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003279"(cardiac septum development)|go:"GO:0005886"(plasma membrane)|refseq:NP_055918.2|reactome:R-HSA-9696270|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0060666"(dichotomous subdivision of terminal units involved in salivary gland branching)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|go:"GO:0005887"(integral component of plasma membrane)|interpro:IPR014756(Immunoglobulin E-set)|go:"GO:0007162"(negative regulation of cell adhesion)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0007416"(synapse assembly)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|go:"GO:0008360"(regulation of cell shape)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019904"(protein domain specific binding)|interpro:IPR036352|interpro:IPR041019|interpro:IPR042719|mint:Q9Y4D7|rcsb pdb:3H6N|go:"GO:0030027"(lamellipodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035904"(aorta development)|go:"GO:0043087"(regulation of GTPase activity)|reactome:R-HSA-416700|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045765"(regulation of angiogenesis)|reactome:R-HSA-9013508|mint:MINT-4507880(identity)	refseq:XP_011508174.1|refseq:XP_011508175.1|refseq:NP_001180229.1|refseq:NP_001180230.1|refseq:NP_001180231.1|refseq:NP_071762.2|ensembl:ENSG00000196189(gene)|ensembl:ENST00000355014(transcript)|ensembl:ENST00000368282(transcript)|ensembl:ENST00000368285(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:1904891"(positive regulation of excitatory synapse assembly)|go:"GO:1905704"(positive regulation of inhibitory synapse assembly)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036352|mint:Q9H3S1|reactome:R-HSA-416700|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|refseq:XP_016857545.1|mint:MINT-4507882(identity)	-	-	-	figure legend:F5C|figure legend:F4B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/03/26	2014/10/16	rogid:9feDx1eMDTqGWO2oQ6tMvrHLATE9606	rogid:mET6IfHJaauZpacRiDhcsm/uDTw9606	intact-crc:915F9286D789796F|rigid:haV/DaKYTaogi9sKd5MKRZqDesY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15041	uniprotkb:Q9Y4D7	intact:EBI-7283693|uniprotkb:Q75M97|uniprotkb:B4E1P1|uniprotkb:Q75M94|intact:MINT-4507944|ensembl:ENSP00000496491	intact:EBI-310731|ensembl:ENSP00000317128|uniprotkb:Q6PJS9|uniprotkb:Q8IZJ2|uniprotkb:Q9BTQ2|uniprotkb:A7E2C6|uniprotkb:C9JPZ6	psi-mi:sem3e_human(display_long)|uniprotkb:SEMA3E(gene name)|psi-mi:SEMA3E(display_short)|uniprotkb:KIAA0331(gene name synonym)|uniprotkb:SEMAH(gene name synonym)	psi-mi:plxd1_human(display_long)|uniprotkb:PLXND1(gene name)|psi-mi:PLXND1(display_short)|uniprotkb:KIAA0620(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Toyofuku et al. (2007)	pubmed:17318185|imex:IM-11385|mint:MINT-5219684	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7283731|mint:MINT-4507966|imex:IM-11385-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036563.1|refseq:NP_001171600.1|ensembl:ENSG00000170381(gene)|ensembl:ENST00000643230(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050808"(synapse organization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015513(Semaphorin 3E)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036179|interpro:IPR036352|mint:O15041|reactome:R-HSA-416700|mint:MINT-4507967(identity)	ensembl:ENSG00000004399(gene)|ensembl:ENST00000324093(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003279"(cardiac septum development)|go:"GO:0005886"(plasma membrane)|refseq:NP_055918.2|reactome:R-HSA-9696270|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0060666"(dichotomous subdivision of terminal units involved in salivary gland branching)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|go:"GO:0005887"(integral component of plasma membrane)|interpro:IPR014756(Immunoglobulin E-set)|go:"GO:0007162"(negative regulation of cell adhesion)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0007416"(synapse assembly)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|go:"GO:0008360"(regulation of cell shape)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019904"(protein domain specific binding)|interpro:IPR036352|interpro:IPR041019|interpro:IPR042719|mint:Q9Y4D7|rcsb pdb:3H6N|go:"GO:0030027"(lamellipodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035904"(aorta development)|go:"GO:0043087"(regulation of GTPase activity)|reactome:R-HSA-416700|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045765"(regulation of angiogenesis)|reactome:R-HSA-9013508|mint:MINT-4507969(identity)	-	comment:mint	-	figure legend:F5D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/03/26	2014/10/16	rogid:m6pJKIlr+wF5rd6krKT5Q1MnE6s9606	rogid:9feDx1eMDTqGWO2oQ6tMvrHLATE9606	intact-crc:6609121DE46BE037|rigid:F17pe6+znq1hkFf1oh/aryrU0yc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9H3S1	uniprotkb:Q9Y4D7	intact:EBI-3924922|uniprotkb:B3KR76|uniprotkb:Q5TCJ6|uniprotkb:B2RDH8|uniprotkb:Q8WUA9|uniprotkb:Q5TCI5|ensembl:ENSP00000347117|ensembl:ENSP00000357265|ensembl:ENSP00000357268	intact:EBI-310731|ensembl:ENSP00000317128|uniprotkb:Q6PJS9|uniprotkb:Q8IZJ2|uniprotkb:Q9BTQ2|uniprotkb:A7E2C6|uniprotkb:C9JPZ6	psi-mi:sem4a_human(display_long)|uniprotkb:SEMA4A(gene name)|psi-mi:SEMA4A(display_short)|uniprotkb:SEMAB(gene name synonym)|uniprotkb:SEMB(gene name synonym)|uniprotkb:Semaphorin-B(gene name synonym)|uniprotkb:UNQ783/PRO1317(orf name)	psi-mi:plxd1_human(display_long)|uniprotkb:PLXND1(gene name)|psi-mi:PLXND1(display_short)|uniprotkb:KIAA0620(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Toyofuku et al. (2007)	pubmed:17318185|imex:IM-11385|mint:MINT-5219684	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7283753|mint:MINT-4507918|imex:IM-11385-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011508174.1|refseq:XP_011508175.1|refseq:NP_001180229.1|refseq:NP_001180230.1|refseq:NP_001180231.1|refseq:NP_071762.2|ensembl:ENSG00000196189(gene)|ensembl:ENST00000355014(transcript)|ensembl:ENST00000368282(transcript)|ensembl:ENST00000368285(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:1904891"(positive regulation of excitatory synapse assembly)|go:"GO:1905704"(positive regulation of inhibitory synapse assembly)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036352|mint:Q9H3S1|reactome:R-HSA-416700|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|refseq:XP_016857545.1|mint:MINT-4507921(identity)	ensembl:ENSG00000004399(gene)|ensembl:ENST00000324093(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003279"(cardiac septum development)|go:"GO:0005886"(plasma membrane)|refseq:NP_055918.2|reactome:R-HSA-9696270|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0060666"(dichotomous subdivision of terminal units involved in salivary gland branching)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|go:"GO:0005887"(integral component of plasma membrane)|interpro:IPR014756(Immunoglobulin E-set)|go:"GO:0007162"(negative regulation of cell adhesion)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0007416"(synapse assembly)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|go:"GO:0008360"(regulation of cell shape)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019904"(protein domain specific binding)|interpro:IPR036352|interpro:IPR041019|interpro:IPR042719|mint:Q9Y4D7|rcsb pdb:3H6N|go:"GO:0030027"(lamellipodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035904"(aorta development)|go:"GO:0043087"(regulation of GTPase activity)|reactome:R-HSA-416700|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045765"(regulation of angiogenesis)|reactome:R-HSA-9013508|mint:MINT-4507919(identity)	-	-	-	figure legend:F5A|kinetics:kd 8,7 nanomolar|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/03/26	2014/10/16	rogid:mET6IfHJaauZpacRiDhcsm/uDTw9606	rogid:9feDx1eMDTqGWO2oQ6tMvrHLATE9606	intact-crc:6875D41FD9A2908D|rigid:haV/DaKYTaogi9sKd5MKRZqDesY	false	-	flag tag:?-?(MINT-4507929)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15041	uniprotkb:Q9Y4D7	intact:EBI-7283693|uniprotkb:Q75M97|uniprotkb:B4E1P1|uniprotkb:Q75M94|intact:MINT-4507944|ensembl:ENSP00000496491	intact:EBI-310731|ensembl:ENSP00000317128|uniprotkb:Q6PJS9|uniprotkb:Q8IZJ2|uniprotkb:Q9BTQ2|uniprotkb:A7E2C6|uniprotkb:C9JPZ6	psi-mi:sem3e_human(display_long)|uniprotkb:SEMA3E(gene name)|psi-mi:SEMA3E(display_short)|uniprotkb:KIAA0331(gene name synonym)|uniprotkb:SEMAH(gene name synonym)	psi-mi:plxd1_human(display_long)|uniprotkb:PLXND1(gene name)|psi-mi:PLXND1(display_short)|uniprotkb:KIAA0620(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Toyofuku et al. (2007)	pubmed:17318185|imex:IM-11385|mint:MINT-5219684	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7283783|mint:MINT-4507932|imex:IM-11385-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036563.1|refseq:NP_001171600.1|ensembl:ENSG00000170381(gene)|ensembl:ENST00000643230(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050808"(synapse organization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015513(Semaphorin 3E)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036179|interpro:IPR036352|mint:O15041|reactome:R-HSA-416700|mint:MINT-4507937(identity)	ensembl:ENSG00000004399(gene)|ensembl:ENST00000324093(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003279"(cardiac septum development)|go:"GO:0005886"(plasma membrane)|refseq:NP_055918.2|reactome:R-HSA-9696270|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0060666"(dichotomous subdivision of terminal units involved in salivary gland branching)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|go:"GO:0005887"(integral component of plasma membrane)|interpro:IPR014756(Immunoglobulin E-set)|go:"GO:0007162"(negative regulation of cell adhesion)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0007416"(synapse assembly)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|go:"GO:0008360"(regulation of cell shape)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0019904"(protein domain specific binding)|interpro:IPR036352|interpro:IPR041019|interpro:IPR042719|mint:Q9Y4D7|rcsb pdb:3H6N|go:"GO:0030027"(lamellipodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035904"(aorta development)|go:"GO:0043087"(regulation of GTPase activity)|reactome:R-HSA-416700|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045765"(regulation of angiogenesis)|reactome:R-HSA-9013508|mint:MINT-4507933(identity)	-	comment:mint	-	figure legend:F5B|kinetics:kd 1,3 nanomolar|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/03/26	2014/10/16	rogid:m6pJKIlr+wF5rd6krKT5Q1MnE6s9606	rogid:9feDx1eMDTqGWO2oQ6tMvrHLATE9606	intact-crc:813C0E88210C9AB5|rigid:F17pe6+znq1hkFf1oh/aryrU0yc	false	-	flag tag:?-?(MINT-4507934)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P42685	uniprotkb:P63000	intact:EBI-1383583|uniprotkb:Q13128|uniprotkb:Q9NTR5|uniprotkb:B4DY49|ensembl:ENSP00000476145	intact:EBI-413628|ensembl:ENSP00000258737|uniprotkb:O95501|uniprotkb:P15154|uniprotkb:Q3Y4D3|uniprotkb:Q5JAA8|uniprotkb:Q9BTB4	psi-mi:frk_human(display_long)|uniprotkb:PTK5(gene name synonym)|uniprotkb:RAK(gene name synonym)|uniprotkb:FYN-related kinase(gene name synonym)|uniprotkb:Nuclear tyrosine protein kinase RAK(gene name synonym)|uniprotkb:FRK(gene name)|psi-mi:FRK(display_short)|uniprotkb:Protein-tyrosine kinase 5(gene name synonym)	psi-mi:rac1_human(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:MIG5(orf name)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Ras-like protein TC25(gene name synonym)|uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)|uniprotkb:TC25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Toyofuku et al. (2007)	pubmed:17318185|imex:IM-11385|mint:MINT-5219684	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7283809|mint:MINT-4507979|imex:IM-11385-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002022.1|refseq:XP_005266937.1|refseq:XP_005266938.1|refseq:XP_005266939.1|refseq:XP_011533955.1|refseq:XP_011533956.1|refseq:XP_011533957.1|refseq:XP_016866134.1|ensembl:ENST00000606080(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045087"(innate immune response)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035805|interpro:IPR036028|interpro:IPR036860|mint:P42685|reactome:R-HSA-6798695|reactome:R-HSA-8948751|ensembl:ENSG00000111816(gene)|mint:MINT-4507980(identity)	ensembl:ENSG00000136238(gene)|ensembl:ENST00000348035(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002551"(mast cell chemotaxis)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006954"(inflammatory response)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031529"(ruffle organization)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032707"(negative regulation of interleukin-23 production)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042470"(melanosome)|reactome:R-HSA-2424491|refseq:NP_008839.2|refseq:NP_061485.1|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051668"(localization within membrane)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902622"(regulation of neutrophil migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P63000|rcsb pdb:1E96|rcsb pdb:1FOE|rcsb pdb:1G4U|rcsb pdb:1HE1|rcsb pdb:1HH4|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:1I4T|rcsb pdb:1MH1|rcsb pdb:1RYF|rcsb pdb:1RYH|rcsb pdb:2FJU|rcsb pdb:2H7V|rcsb pdb:2NZ8|rcsb pdb:2P2L|rcsb pdb:2RMK|rcsb pdb:2VRW|rcsb pdb:2WKP|rcsb pdb:2WKQ|rcsb pdb:2WKR|rcsb pdb:2YIN|rcsb pdb:3B13|rcsb pdb:3BJI|rcsb pdb:3RYT|rcsb pdb:3SBD|rcsb pdb:3SBE|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:3TH5|rcsb pdb:4GZL|rcsb pdb:4GZM|rcsb pdb:4YON|rcsb pdb:5FI0|rcsb pdb:5HZH|rcsb pdb:5N6O|rcsb pdb:5O33|rcsb pdb:5QQD|rcsb pdb:5QQE|rcsb pdb:5QQF|rcsb pdb:5QQG|rcsb pdb:5QQH|rcsb pdb:5QQI|rcsb pdb:5QQJ|rcsb pdb:5QQK|rcsb pdb:5QQL|rcsb pdb:5QQM|rcsb pdb:5QQN|rcsb pdb:5QU9|rcsb pdb:6AGP|rcsb pdb:6BC1|rcsb pdb:6TGC|rcsb pdb:6X1G|rcsb pdb:7AJK|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1445148|reactome:R-HSA-164944|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0045453"(bone resorption)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051492"(regulation of stress fiber assembly)|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-389359|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-4086400|reactome:R-HSA-416550|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5668599|reactome:R-HSA-5687128|reactome:R-HSA-6798695|reactome:R-HSA-6811558|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-9013149|reactome:R-HSA-9032759|reactome:R-HSA-9032845|reactome:R-HSA-9619229|reactome:R-HSA-9664422|reactome:R-HSA-9673324|reactome:R-HSA-983231|reactome:R-HSA-2871796|reactome:R-HSA-376172|dip:DIP-29260N|mint:MINT-4507982(identity)	-	-	-	figure legend:F6B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/03/26	2014/10/16	rogid:WP3N8FqRu6wIouk2iA0zJ1qmDRw9606	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9606	intact-crc:D59990AC1486B9E0|rigid:hA2YMbn4wI1IgX0yXvRSxIjEsjk	false	glutathione s tranferase tag:?-?(MINT-4507985)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)