#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O70161 uniprotkb:P17426-1 intact:EBI-773657|uniprotkb:Q505A1|uniprotkb:Q80TW9|uniprotkb:Q8VCU5|ensembl:ENSMUSP00000100964 intact:EBI-775207|intact:EBI-7256976|intact:MINT-1865033|ensembl:ENSMUSP00000082519|ensembl:ENSMUSP00000127842 psi-mi:pi51c_mouse(display_long)|uniprotkb:Pip5k1c(gene name)|psi-mi:Pip5k1c(display_short)|uniprotkb:Kiaa0589(gene name synonym)|uniprotkb:Phosphatidylinositol 4-phosphate 5-kinase type I gamma(gene name synonym) psi-mi:p17426-1(display_long)|uniprotkb:Ap2a1(gene name)|psi-mi:Ap2a1(display_short)|uniprotkb:Adtaa(gene name synonym)|uniprotkb:Clapa1(gene name synonym)|uniprotkb:100 kDa coated vesicle protein A(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-1(gene name synonym)|uniprotkb:Alpha-adaptin A(gene name synonym)|uniprotkb:Alpha1-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-A large chain(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nakano-Kobayashi et al. (2007) pubmed:17290217|imex:IM-11202|mint:MINT-5219608 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7256967|mint:MINT-4329367|imex:IM-11202-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140159.1|refseq:NP_032870.2|refseq:NP_001280575.1|refseq:NP_001280576.1|ensembl:ENSMUSG00000034902(gene)|ensembl:ENSMUST00000105327(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001931"(uropod)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007409"(axonogenesis)|go:"GO:0010008"(endosome membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0070527"(platelet aggregation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:O70161|rcsb pdb:1Y19|rcsb pdb:2H7D|rcsb pdb:2H7E|reactome:R-MMU-1660499|reactome:R-MMU-399955|reactome:R-MMU-6811558|reactome:R-MMU-8856828|mint:MINT-4329368(identity) intact:EBI-775189(ap2a1_mouse)|ensembl:ENSMUSG00000060279(gene)|ensembl:ENSMUST00000085399(transcript)|ensembl:ENSMUST00000166972(transcript)|mint:MINT-4329369(identity) - - - figure legend:F5B|figure legend:F1A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2007/03/02 2014/10/16 rogid:nyRuUZQSpe2dc2XN1CZV8Oy5Yvk10090 rogid:Dd6Q+Et/LTlmo5qpro2Zaeq0dMc10090 intact-crc:38225CAB47CB44BF|rigid:F8EAK9zOHtqjeinY9XjBvCl3kpI false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9DBG3-2 uniprotkb:O70161 intact:EBI-7257021|intact:MINT-4087969|ensembl:ENSMUSP00000018875 intact:EBI-773657|uniprotkb:Q505A1|uniprotkb:Q80TW9|uniprotkb:Q8VCU5|ensembl:ENSMUSP00000100964 psi-mi:q9dbg3-2(display_long)|uniprotkb:Clapb1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Ap2b1(gene name)|psi-mi:Ap2b1(display_short)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym) psi-mi:pi51c_mouse(display_long)|uniprotkb:Pip5k1c(gene name)|psi-mi:Pip5k1c(display_short)|uniprotkb:Kiaa0589(gene name synonym)|uniprotkb:Phosphatidylinositol 4-phosphate 5-kinase type I gamma(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nakano-Kobayashi et al. (2007) pubmed:17290217|imex:IM-11202|mint:MINT-5219608 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7257036|mint:MINT-4329385|imex:IM-11202-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-775229(isoform-parent)|ensembl:ENSMUSG00000035152(gene)|ensembl:ENSMUST00000018875(transcript)|mint:MINT-4329389(identity) refseq:NP_001140159.1|refseq:NP_032870.2|refseq:NP_001280575.1|refseq:NP_001280576.1|ensembl:ENSMUSG00000034902(gene)|ensembl:ENSMUST00000105327(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001931"(uropod)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007409"(axonogenesis)|go:"GO:0010008"(endosome membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0070527"(platelet aggregation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:O70161|rcsb pdb:1Y19|rcsb pdb:2H7D|rcsb pdb:2H7E|reactome:R-MMU-1660499|reactome:R-MMU-399955|reactome:R-MMU-6811558|reactome:R-MMU-8856828|mint:MINT-4329386(identity) - comment:mint - figure legend:F5B|figure legend:F1A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2007/03/02 2014/10/16 rogid:QRixC0CP1GtA4K5ngbsOh/oatD410090 rogid:nyRuUZQSpe2dc2XN1CZV8Oy5Yvk10090 intact-crc:D522DB7C37D95E49|rigid:vfcrA44d0Gbi5k39t+A88bFwoiA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q9DBG3-2 uniprotkb:O70161 intact:EBI-7257021|intact:MINT-4087969|ensembl:ENSMUSP00000018875 intact:EBI-773657|uniprotkb:Q505A1|uniprotkb:Q80TW9|uniprotkb:Q8VCU5|ensembl:ENSMUSP00000100964 psi-mi:q9dbg3-2(display_long)|uniprotkb:Clapb1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Ap2b1(gene name)|psi-mi:Ap2b1(display_short)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym) psi-mi:pi51c_mouse(display_long)|uniprotkb:Pip5k1c(gene name)|psi-mi:Pip5k1c(display_short)|uniprotkb:Kiaa0589(gene name synonym)|uniprotkb:Phosphatidylinositol 4-phosphate 5-kinase type I gamma(gene name synonym) psi-mi:"MI:0096"(pull down) Nakano-Kobayashi et al. (2007) pubmed:17290217|imex:IM-11202|mint:MINT-5219608 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7257092|mint:MINT-4329415|imex:IM-11202-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-775229(isoform-parent)|ensembl:ENSMUSG00000035152(gene)|ensembl:ENSMUST00000018875(transcript)|mint:MINT-4329416(identity) refseq:NP_001140159.1|refseq:NP_032870.2|refseq:NP_001280575.1|refseq:NP_001280576.1|ensembl:ENSMUSG00000034902(gene)|ensembl:ENSMUST00000105327(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001931"(uropod)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007409"(axonogenesis)|go:"GO:0010008"(endosome membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0070527"(platelet aggregation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:O70161|rcsb pdb:1Y19|rcsb pdb:2H7D|rcsb pdb:2H7E|reactome:R-MMU-1660499|reactome:R-MMU-399955|reactome:R-MMU-6811558|reactome:R-MMU-8856828|mint:MINT-4329421(identity) - comment:mint - figure legend:F1E|figure legend:F2B|figure legend:F2D|figure legend:F2C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/02 2014/10/16 rogid:QRixC0CP1GtA4K5ngbsOh/oatD410090 rogid:nyRuUZQSpe2dc2XN1CZV8Oy5Yvk10090 intact-crc:3A667788CA75CC6F|rigid:vfcrA44d0Gbi5k39t+A88bFwoiA false binding-associated region:?-?(MINT-4329431)|glutathione s tranferase tag:?-?(MINT-4329418) binding-associated region:635-661(MINT-4329513)|flag tag:?-?(MINT-4329424) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9DBG3-2 uniprotkb:O70161 intact:EBI-7257021|intact:MINT-4087969|ensembl:ENSMUSP00000018875 intact:EBI-773657|uniprotkb:Q505A1|uniprotkb:Q80TW9|uniprotkb:Q8VCU5|ensembl:ENSMUSP00000100964 psi-mi:q9dbg3-2(display_long)|uniprotkb:Clapb1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Ap2b1(gene name)|psi-mi:Ap2b1(display_short)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym) psi-mi:pi51c_mouse(display_long)|uniprotkb:Pip5k1c(gene name)|psi-mi:Pip5k1c(display_short)|uniprotkb:Kiaa0589(gene name synonym)|uniprotkb:Phosphatidylinositol 4-phosphate 5-kinase type I gamma(gene name synonym) psi-mi:"MI:0096"(pull down) Nakano-Kobayashi et al. (2007) pubmed:17290217|imex:IM-11202|mint:MINT-5219608 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7257059|mint:MINT-4329397|imex:IM-11202-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-775229(isoform-parent)|ensembl:ENSMUSG00000035152(gene)|ensembl:ENSMUST00000018875(transcript)|mint:MINT-4329398(identity) refseq:NP_001140159.1|refseq:NP_032870.2|refseq:NP_001280575.1|refseq:NP_001280576.1|ensembl:ENSMUSG00000034902(gene)|ensembl:ENSMUST00000105327(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001931"(uropod)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007409"(axonogenesis)|go:"GO:0010008"(endosome membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0070527"(platelet aggregation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:O70161|rcsb pdb:1Y19|rcsb pdb:2H7D|rcsb pdb:2H7E|reactome:R-MMU-1660499|reactome:R-MMU-399955|reactome:R-MMU-6811558|reactome:R-MMU-8856828|mint:MINT-4329402(identity) - comment:mint - figure legend:F1C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/02 2014/10/16 rogid:QRixC0CP1GtA4K5ngbsOh/oatD410090 rogid:nyRuUZQSpe2dc2XN1CZV8Oy5Yvk10090 intact-crc:AA116BB125A1FDD1|rigid:vfcrA44d0Gbi5k39t+A88bFwoiA false glutathione s tranferase tag:?-?(MINT-4329412) myc tag:?-?(MINT-4329409) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9DBG3-2 uniprotkb:O70161 intact:EBI-7257021|intact:MINT-4087969|ensembl:ENSMUSP00000018875 intact:EBI-773657|uniprotkb:Q505A1|uniprotkb:Q80TW9|uniprotkb:Q8VCU5|ensembl:ENSMUSP00000100964 psi-mi:q9dbg3-2(display_long)|uniprotkb:Clapb1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Ap2b1(gene name)|psi-mi:Ap2b1(display_short)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym) psi-mi:pi51c_mouse(display_long)|uniprotkb:Pip5k1c(gene name)|psi-mi:Pip5k1c(display_short)|uniprotkb:Kiaa0589(gene name synonym)|uniprotkb:Phosphatidylinositol 4-phosphate 5-kinase type I gamma(gene name synonym) psi-mi:"MI:0096"(pull down) Nakano-Kobayashi et al. (2007) pubmed:17290217|imex:IM-11202|mint:MINT-5219608 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7257121|mint:MINT-4329435|imex:IM-11202-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-775229(isoform-parent)|ensembl:ENSMUSG00000035152(gene)|ensembl:ENSMUST00000018875(transcript)|mint:MINT-4329441(identity) refseq:NP_001140159.1|refseq:NP_032870.2|refseq:NP_001280575.1|refseq:NP_001280576.1|ensembl:ENSMUSG00000034902(gene)|ensembl:ENSMUST00000105327(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001931"(uropod)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007409"(axonogenesis)|go:"GO:0010008"(endosome membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0070527"(platelet aggregation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:O70161|rcsb pdb:1Y19|rcsb pdb:2H7D|rcsb pdb:2H7E|reactome:R-MMU-1660499|reactome:R-MMU-399955|reactome:R-MMU-6811558|reactome:R-MMU-8856828|mint:MINT-4329436(identity) - comment:mint - figure legend:F1F|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/02 2014/10/16 rogid:QRixC0CP1GtA4K5ngbsOh/oatD410090 rogid:nyRuUZQSpe2dc2XN1CZV8Oy5Yvk10090 intact-crc:4B08E40064A59589|rigid:vfcrA44d0Gbi5k39t+A88bFwoiA false glutathione s tranferase tag:?-?(MINT-4329444)|binding-associated region:?-?(MINT-4329442) flag tag:?-?(MINT-4329437) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9DBG3-2 uniprotkb:O70161 intact:EBI-7257021|intact:MINT-4087969|ensembl:ENSMUSP00000018875 intact:EBI-773657|uniprotkb:Q505A1|uniprotkb:Q80TW9|uniprotkb:Q8VCU5|ensembl:ENSMUSP00000100964 psi-mi:q9dbg3-2(display_long)|uniprotkb:Clapb1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Ap2b1(gene name)|psi-mi:Ap2b1(display_short)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym) psi-mi:pi51c_mouse(display_long)|uniprotkb:Pip5k1c(gene name)|psi-mi:Pip5k1c(display_short)|uniprotkb:Kiaa0589(gene name synonym)|uniprotkb:Phosphatidylinositol 4-phosphate 5-kinase type I gamma(gene name synonym) psi-mi:"MI:0096"(pull down) Nakano-Kobayashi et al. (2007) pubmed:17290217|imex:IM-11202|mint:MINT-5219608 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7257187|mint:MINT-4329579|imex:IM-11202-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-775229(isoform-parent)|ensembl:ENSMUSG00000035152(gene)|ensembl:ENSMUST00000018875(transcript)|mint:MINT-4329587(identity) refseq:NP_001140159.1|refseq:NP_032870.2|refseq:NP_001280575.1|refseq:NP_001280576.1|ensembl:ENSMUSG00000034902(gene)|ensembl:ENSMUST00000105327(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001931"(uropod)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007409"(axonogenesis)|go:"GO:0010008"(endosome membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0070527"(platelet aggregation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:O70161|rcsb pdb:1Y19|rcsb pdb:2H7D|rcsb pdb:2H7E|reactome:R-MMU-1660499|reactome:R-MMU-399955|reactome:R-MMU-6811558|reactome:R-MMU-8856828|mint:MINT-4329580(identity) - comment:mint - figure legend:F4F|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/02 2014/10/16 rogid:QRixC0CP1GtA4K5ngbsOh/oatD410090 rogid:nyRuUZQSpe2dc2XN1CZV8Oy5Yvk10090 intact-crc:0A68490B9A838F30|rigid:vfcrA44d0Gbi5k39t+A88bFwoiA false glutathione s tranferase tag:?-?(MINT-4329590)|binding-associated region:?-?(MINT-4329588) green fluorescent protein tag:?-?(MINT-4329583)|binding-associated region:635-661(MINT-4329581) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9DBG3-2 uniprotkb:O70161 intact:EBI-7257021|intact:MINT-4087969|ensembl:ENSMUSP00000018875 intact:EBI-773657|uniprotkb:Q505A1|uniprotkb:Q80TW9|uniprotkb:Q8VCU5|ensembl:ENSMUSP00000100964 psi-mi:q9dbg3-2(display_long)|uniprotkb:Clapb1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Ap2b1(gene name)|psi-mi:Ap2b1(display_short)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym) psi-mi:pi51c_mouse(display_long)|uniprotkb:Pip5k1c(gene name)|psi-mi:Pip5k1c(display_short)|uniprotkb:Kiaa0589(gene name synonym)|uniprotkb:Phosphatidylinositol 4-phosphate 5-kinase type I gamma(gene name synonym) psi-mi:"MI:0096"(pull down) Nakano-Kobayashi et al. (2007) pubmed:17290217|imex:IM-11202|mint:MINT-5219608 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7257143|mint:MINT-4329516|imex:IM-11202-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-775229(isoform-parent)|ensembl:ENSMUSG00000035152(gene)|ensembl:ENSMUST00000018875(transcript)|mint:MINT-4329524(identity) refseq:NP_001140159.1|refseq:NP_032870.2|refseq:NP_001280575.1|refseq:NP_001280576.1|ensembl:ENSMUSG00000034902(gene)|ensembl:ENSMUST00000105327(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001931"(uropod)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007409"(axonogenesis)|go:"GO:0010008"(endosome membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0070527"(platelet aggregation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:O70161|rcsb pdb:1Y19|rcsb pdb:2H7D|rcsb pdb:2H7E|reactome:R-MMU-1660499|reactome:R-MMU-399955|reactome:R-MMU-6811558|reactome:R-MMU-8856828|mint:MINT-4329517(identity) - comment:mint - figure legend:F4E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/02 2014/10/16 rogid:QRixC0CP1GtA4K5ngbsOh/oatD410090 rogid:nyRuUZQSpe2dc2XN1CZV8Oy5Yvk10090 intact-crc:385167EF11EF300A|rigid:vfcrA44d0Gbi5k39t+A88bFwoiA false glutathione s tranferase tag:?-?(MINT-4329527)|binding-associated region:?-?(MINT-4329525) mutation disrupting interaction:645-645(MINT-4329535)|flag tag:?-?(MINT-4329520) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9DBG3-2 uniprotkb:O70161 intact:EBI-7257021|intact:MINT-4087969|ensembl:ENSMUSP00000018875 intact:EBI-773657|uniprotkb:Q505A1|uniprotkb:Q80TW9|uniprotkb:Q8VCU5|ensembl:ENSMUSP00000100964 psi-mi:q9dbg3-2(display_long)|uniprotkb:Clapb1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Ap2b1(gene name)|psi-mi:Ap2b1(display_short)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym) psi-mi:pi51c_mouse(display_long)|uniprotkb:Pip5k1c(gene name)|psi-mi:Pip5k1c(display_short)|uniprotkb:Kiaa0589(gene name synonym)|uniprotkb:Phosphatidylinositol 4-phosphate 5-kinase type I gamma(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nakano-Kobayashi et al. (2007) pubmed:17290217|imex:IM-11202|mint:MINT-5219608 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7257320|mint:MINT-4329453|imex:IM-11202-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-775229(isoform-parent)|ensembl:ENSMUSG00000035152(gene)|ensembl:ENSMUST00000018875(transcript)|mint:MINT-4329454(identity) refseq:NP_001140159.1|refseq:NP_032870.2|refseq:NP_001280575.1|refseq:NP_001280576.1|ensembl:ENSMUSG00000034902(gene)|ensembl:ENSMUST00000105327(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001931"(uropod)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007409"(axonogenesis)|go:"GO:0010008"(endosome membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0070527"(platelet aggregation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:O70161|rcsb pdb:1Y19|rcsb pdb:2H7D|rcsb pdb:2H7E|reactome:R-MMU-1660499|reactome:R-MMU-399955|reactome:R-MMU-6811558|reactome:R-MMU-8856828|mint:MINT-4329461(identity) - comment:mint - figure legend:F1D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2007/03/02 2014/10/16 rogid:QRixC0CP1GtA4K5ngbsOh/oatD410090 rogid:nyRuUZQSpe2dc2XN1CZV8Oy5Yvk10090 intact-crc:13D7F0DA1BA0E955|rigid:vfcrA44d0Gbi5k39t+A88bFwoiA false ha tag:?-?(MINT-4329456) flag tag:?-?(MINT-4329463) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9DBG3-1 uniprotkb:O70161 intact:EBI-775239|intact:EBI-7257420|intact:MINT-4087966|intact:EBI-7257476|intact:EBI-7257338|ensembl:ENSMUSP00000070714 intact:EBI-773657|uniprotkb:Q505A1|uniprotkb:Q80TW9|uniprotkb:Q8VCU5|ensembl:ENSMUSP00000100964 psi-mi:q9dbg3-1(display_long)|uniprotkb:Ap2b1(gene name)|psi-mi:Ap2b1(display_short)|uniprotkb:Clapb1(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym) psi-mi:pi51c_mouse(display_long)|uniprotkb:Pip5k1c(gene name)|psi-mi:Pip5k1c(display_short)|uniprotkb:Kiaa0589(gene name synonym)|uniprotkb:Phosphatidylinositol 4-phosphate 5-kinase type I gamma(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nakano-Kobayashi et al. (2007) pubmed:17290217|imex:IM-11202|mint:MINT-5219608 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7257353|mint:MINT-4329473|imex:IM-11202-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-775229(ap2b1_mouse)|ensembl:ENSMUSG00000035152(gene)|ensembl:ENSMUST00000065692(transcript)|mint:MINT-4329479(identity) refseq:NP_001140159.1|refseq:NP_032870.2|refseq:NP_001280575.1|refseq:NP_001280576.1|ensembl:ENSMUSG00000034902(gene)|ensembl:ENSMUST00000105327(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001931"(uropod)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007409"(axonogenesis)|go:"GO:0010008"(endosome membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0070527"(platelet aggregation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:O70161|rcsb pdb:1Y19|rcsb pdb:2H7D|rcsb pdb:2H7E|reactome:R-MMU-1660499|reactome:R-MMU-399955|reactome:R-MMU-6811558|reactome:R-MMU-8856828|mint:MINT-4329474(identity) - - - figure legend:F1D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2007/03/02 2014/10/16 rogid:YWwOqRpXCJDwzrLv27muBx1+DHI10090 rogid:nyRuUZQSpe2dc2XN1CZV8Oy5Yvk10090 intact-crc:0B692A3367B8F956|rigid:spFJe6RGfHmF9e0izhpx9Th4Kc0 false ha tag:?-?(MINT-4329481) flag tag:?-?(MINT-4329477) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9DBG3-2 uniprotkb:O70161 intact:EBI-7257021|intact:MINT-4087969|ensembl:ENSMUSP00000018875 intact:EBI-773657|uniprotkb:Q505A1|uniprotkb:Q80TW9|uniprotkb:Q8VCU5|ensembl:ENSMUSP00000100964 psi-mi:q9dbg3-2(display_long)|uniprotkb:Clapb1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Ap2b1(gene name)|psi-mi:Ap2b1(display_short)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym) psi-mi:pi51c_mouse(display_long)|uniprotkb:Pip5k1c(gene name)|psi-mi:Pip5k1c(display_short)|uniprotkb:Kiaa0589(gene name synonym)|uniprotkb:Phosphatidylinositol 4-phosphate 5-kinase type I gamma(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nakano-Kobayashi et al. (2007) pubmed:17290217|imex:IM-11202|mint:MINT-5219608 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7257388|mint:MINT-4329539|imex:IM-11202-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-775229(isoform-parent)|ensembl:ENSMUSG00000035152(gene)|ensembl:ENSMUST00000018875(transcript)|mint:MINT-4329545(identity) refseq:NP_001140159.1|refseq:NP_032870.2|refseq:NP_001280575.1|refseq:NP_001280576.1|ensembl:ENSMUSG00000034902(gene)|ensembl:ENSMUST00000105327(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001931"(uropod)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007409"(axonogenesis)|go:"GO:0010008"(endosome membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0070527"(platelet aggregation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:O70161|rcsb pdb:1Y19|rcsb pdb:2H7D|rcsb pdb:2H7E|reactome:R-MMU-1660499|reactome:R-MMU-399955|reactome:R-MMU-6811558|reactome:R-MMU-8856828|mint:MINT-4329540(identity) - comment:mint - figure legend:F4D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2007/03/02 2014/10/16 rogid:QRixC0CP1GtA4K5ngbsOh/oatD410090 rogid:nyRuUZQSpe2dc2XN1CZV8Oy5Yvk10090 intact-crc:14A3685A57264175|rigid:vfcrA44d0Gbi5k39t+A88bFwoiA false ha tag:?-?(MINT-4329547) binding-associated region:635-661(MINT-4509419)|flag tag:?-?(MINT-4329543) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9DBG3-1 uniprotkb:O70161 intact:EBI-775239|intact:EBI-7257420|intact:MINT-4087966|intact:EBI-7257476|intact:EBI-7257338|ensembl:ENSMUSP00000070714 intact:EBI-773657|uniprotkb:Q505A1|uniprotkb:Q80TW9|uniprotkb:Q8VCU5|ensembl:ENSMUSP00000100964 psi-mi:q9dbg3-1(display_long)|uniprotkb:Ap2b1(gene name)|psi-mi:Ap2b1(display_short)|uniprotkb:Clapb1(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym) psi-mi:pi51c_mouse(display_long)|uniprotkb:Pip5k1c(gene name)|psi-mi:Pip5k1c(display_short)|uniprotkb:Kiaa0589(gene name synonym)|uniprotkb:Phosphatidylinositol 4-phosphate 5-kinase type I gamma(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Nakano-Kobayashi et al. (2007) pubmed:17290217|imex:IM-11202|mint:MINT-5219608 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7257435|mint:MINT-4329487|imex:IM-11202-9 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-775229(ap2b1_mouse)|ensembl:ENSMUSG00000035152(gene)|ensembl:ENSMUST00000065692(transcript)|mint:MINT-4329488(identity) refseq:NP_001140159.1|refseq:NP_032870.2|refseq:NP_001280575.1|refseq:NP_001280576.1|ensembl:ENSMUSG00000034902(gene)|ensembl:ENSMUST00000105327(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001931"(uropod)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007409"(axonogenesis)|go:"GO:0010008"(endosome membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0070527"(platelet aggregation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:O70161|rcsb pdb:1Y19|rcsb pdb:2H7D|rcsb pdb:2H7E|reactome:R-MMU-1660499|reactome:R-MMU-399955|reactome:R-MMU-6811558|reactome:R-MMU-8856828|mint:MINT-4329494(identity) - - - figure legend:F3A|figure legend:F3B|figure legend:F3C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/02 2014/10/16 rogid:YWwOqRpXCJDwzrLv27muBx1+DHI10090 rogid:nyRuUZQSpe2dc2XN1CZV8Oy5Yvk10090 intact-crc:6CA3D10FA5CC7490|rigid:spFJe6RGfHmF9e0izhpx9Th4Kc0 false binding-associated region:?-?(MINT-4329507) mutation disrupting interaction:277-277(MINT-4329503)|glutathione s tranferase tag:?-?(MINT-4329495) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O70161 uniprotkb:Q9DBG3-1 intact:EBI-773657|uniprotkb:Q505A1|uniprotkb:Q80TW9|uniprotkb:Q8VCU5|ensembl:ENSMUSP00000100964 intact:EBI-775239|intact:EBI-7257420|intact:MINT-4087966|intact:EBI-7257476|intact:EBI-7257338|ensembl:ENSMUSP00000070714 psi-mi:pi51c_mouse(display_long)|uniprotkb:Pip5k1c(gene name)|psi-mi:Pip5k1c(display_short)|uniprotkb:Kiaa0589(gene name synonym)|uniprotkb:Phosphatidylinositol 4-phosphate 5-kinase type I gamma(gene name synonym) psi-mi:q9dbg3-1(display_long)|uniprotkb:Ap2b1(gene name)|psi-mi:Ap2b1(display_short)|uniprotkb:Clapb1(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Nakano-Kobayashi et al. (2007) pubmed:17290217|imex:IM-11202|mint:MINT-5219608 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7257491|mint:MINT-4329557|imex:IM-11202-8 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140159.1|refseq:NP_032870.2|refseq:NP_001280575.1|refseq:NP_001280576.1|ensembl:ENSMUSG00000034902(gene)|ensembl:ENSMUST00000105327(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001931"(uropod)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007409"(axonogenesis)|go:"GO:0010008"(endosome membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0070527"(platelet aggregation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:O70161|rcsb pdb:1Y19|rcsb pdb:2H7D|rcsb pdb:2H7E|reactome:R-MMU-1660499|reactome:R-MMU-399955|reactome:R-MMU-6811558|reactome:R-MMU-8856828|mint:MINT-4329563(identity) intact:EBI-775229(ap2b1_mouse)|ensembl:ENSMUSG00000035152(gene)|ensembl:ENSMUST00000065692(transcript)|mint:MINT-4329558(identity) - - - figure legend:F4G|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/02 2014/10/16 rogid:nyRuUZQSpe2dc2XN1CZV8Oy5Yvk10090 rogid:YWwOqRpXCJDwzrLv27muBx1+DHI10090 intact-crc:A40201C26A431C64|rigid:spFJe6RGfHmF9e0izhpx9Th4Kc0 false mutation disrupting interaction:645-645(MINT-4329564)|binding-associated region:635-661(MINT-4509422)|flag tag:?-?(MINT-4329567) glutathione s tranferase tag:?-?(MINT-4329576) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O70161 uniprotkb:P46096 intact:EBI-773657|uniprotkb:Q505A1|uniprotkb:Q80TW9|uniprotkb:Q8VCU5|ensembl:ENSMUSP00000100964 intact:EBI-445340|ensembl:ENSMUSP00000063293|ensembl:ENSMUSP00000100912 psi-mi:pi51c_mouse(display_long)|uniprotkb:Pip5k1c(gene name)|psi-mi:Pip5k1c(display_short)|uniprotkb:Kiaa0589(gene name synonym)|uniprotkb:Phosphatidylinositol 4-phosphate 5-kinase type I gamma(gene name synonym) psi-mi:syt1_mouse(display_long)|uniprotkb:Synaptotagmin I(gene name synonym)|uniprotkb:p65(gene name synonym)|uniprotkb:Syt1(gene name)|psi-mi:Syt1(display_short) psi-mi:"MI:0428"(imaging technique) Nakano-Kobayashi et al. (2007) pubmed:17290217|imex:IM-11202|mint:MINT-5219608 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7257545|mint:MINT-4329599|imex:IM-11202-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140159.1|refseq:NP_032870.2|refseq:NP_001280575.1|refseq:NP_001280576.1|ensembl:ENSMUSG00000034902(gene)|ensembl:ENSMUST00000105327(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001931"(uropod)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007409"(axonogenesis)|go:"GO:0010008"(endosome membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0070527"(platelet aggregation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:O70161|rcsb pdb:1Y19|rcsb pdb:2H7D|rcsb pdb:2H7E|reactome:R-MMU-1660499|reactome:R-MMU-399955|reactome:R-MMU-6811558|reactome:R-MMU-8856828|mint:MINT-4329607(identity) refseq:NP_001239271.1|refseq:NP_033332.1|refseq:XP_006513509.1|refseq:XP_006513510.1|refseq:XP_006513511.1|refseq:NP_001239270.1|ensembl:ENSMUSG00000035864(gene)|ensembl:ENSMUST00000064054(transcript)|ensembl:ENSMUST00000105276(transcript)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030154"(cell differentiation)|go:"GO:0030276"(clathrin binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030348"(syntaxin-3 binding)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031045"(dense core granule)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0033603"(positive regulation of dopamine secretion)|go:"GO:0042584"(chromaffin granule membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048278"(vesicle docking)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0000149"(SNARE binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|refseq:XP_017169355.1|go:"GO:0060076"(excitatory synapse)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0061891"(calcium ion sensor activity)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071911"(synchronous neurotransmitter secretion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098746"(fast, calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099502"(calcium-dependent activation of synaptic vesicle fusion)|go:"GO:1903235"(positive regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001565(Synaptotagmin)|interpro:IPR015428(Synaptotagmin 1,2)|interpro:IPR035892|mint:P46096|rcsb pdb:5T0R|rcsb pdb:5T0S|rcsb pdb:5VFE|rcsb pdb:5VFF|rcsb pdb:5VFG|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|reactome:R-MMU-264642|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-888590|dip:DIP-31322N|mint:MINT-4329600(identity) - - - figure legend:F5E|figure legend:F5F|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain_hippocampal_neuron)|taxid:10090(Mus musculus, brain, hippocampal neurons) - 2007/03/02 2014/10/16 rogid:nyRuUZQSpe2dc2XN1CZV8Oy5Yvk10090 rogid:CxQGrKu3l0pEzQ3aJZBJ/GZMyEA10090 intact-crc:C119762E3B42C6FB|rigid:OsF9LFVzktKPWFeCzMWccmhhz04 false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification)