#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P41811 uniprotkb:P40343 intact:EBI-4898|uniprotkb:D6VU12|ensemblfungi:YGL137W intact:EBI-20380|uniprotkb:D6W1I1|ensemblfungi:YNR006W psi-mi:copb2_yeast(display_long)|uniprotkb:SEC27(gene name)|psi-mi:SEC27(display_short)|uniprotkb:YGL137W(locus name)|uniprotkb:G2827(orf name)|uniprotkb:Beta'-coat protein(gene name synonym) psi-mi:vps27_yeast(display_long)|uniprotkb:VPS27(gene name)|psi-mi:VPS27(display_short)|uniprotkb:YNR006W(locus name)|uniprotkb:N2038(orf name)|uniprotkb:DID7(gene name synonym)|uniprotkb:SSV17(gene name synonym)|uniprotkb:VPL23(gene name synonym)|uniprotkb:VPT27(gene name synonym)|uniprotkb:Golgi retention defective protein 11(gene name synonym)|uniprotkb:GRD11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gabriely et al. (2007) pubmed:17101773|imex:IM-19982 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1552237|imex:IM-19982-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011378.1|sgd:S000003105|dip:DIP-6468N|mint:P41811|ensemblfungi:YGL137W(gene)|ensemblfungi:YGL137W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|rcsb pdb:2YNN|rcsb pdb:2YNO|rcsb pdb:2YNP|rcsb pdb:4J73|rcsb pdb:4J77|rcsb pdb:4J78|rcsb pdb:4J79|rcsb pdb:4J81|rcsb pdb:4J82|rcsb pdb:4J84|rcsb pdb:4J86|reactome:R-SCE-6807878|reactome:R-SCE-6811434 sgd:S000005289|refseq:NP_014403.3|ensemblfungi:YNR006W(gene)|ensemblfungi:YNR006W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0140504"(microlipophagy)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|rcsb pdb:1O06|rcsb pdb:1Q0V|rcsb pdb:1Q0W|rcsb pdb:1VFY|rcsb pdb:2KDI|rcsb pdb:2PJW|rcsb pdb:3R42|rcsb pdb:6NJG|dip:DIP-1741N|mint:P40343 - crc64:6A5E50BBEB02CB58 crc64:76C4501B0EBC9C84 figure legend:Fig. 5A & 5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/11/06 2014/10/16 rogid:I39s3JCseIpdjMGPdNLqEgH8SGk559292 rogid:5ScB34gSI3x260kAGh/knEWupwA559292 intact-crc:FFA7D541F6FB04F4|rigid:P0IFHHoLxBL8wwfEzLDzxICDRkw false myc tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P40509 uniprotkb:P40343 intact:EBI-4884|uniprotkb:D6VVK8|ensemblfungi:YIL076W intact:EBI-20380|uniprotkb:D6W1I1|ensemblfungi:YNR006W psi-mi:cope_yeast(display_long)|uniprotkb:SEC28(gene name)|psi-mi:SEC28(display_short)|uniprotkb:YIL076W(locus name)|uniprotkb:Epsilon-coat protein(gene name synonym) psi-mi:vps27_yeast(display_long)|uniprotkb:VPS27(gene name)|psi-mi:VPS27(display_short)|uniprotkb:YNR006W(locus name)|uniprotkb:N2038(orf name)|uniprotkb:DID7(gene name synonym)|uniprotkb:SSV17(gene name synonym)|uniprotkb:VPL23(gene name synonym)|uniprotkb:VPT27(gene name synonym)|uniprotkb:Golgi retention defective protein 11(gene name synonym)|uniprotkb:GRD11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gabriely et al. (2007) pubmed:17101773|imex:IM-19982 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1552265|imex:IM-19982-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012189.2|sgd:S000001338|dip:DIP-4711N|mint:P40509|ensemblfungi:YIL076W(gene)|ensemblfungi:YIL076W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006901"(vesicle coating)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR006822(Coatomer, epsilon subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434 sgd:S000005289|refseq:NP_014403.3|ensemblfungi:YNR006W(gene)|ensemblfungi:YNR006W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0140504"(microlipophagy)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|rcsb pdb:1O06|rcsb pdb:1Q0V|rcsb pdb:1Q0W|rcsb pdb:1VFY|rcsb pdb:2KDI|rcsb pdb:2PJW|rcsb pdb:3R42|rcsb pdb:6NJG|dip:DIP-1741N|mint:P40343 - crc64:95ACA8BB647817DB crc64:76C4501B0EBC9C84 figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/11/06 2014/10/16 rogid:mESavZmt7IyCa/6WZstYCYgXlcM559292 rogid:5ScB34gSI3x260kAGh/knEWupwA559292 intact-crc:B87F77BCF37F5778|rigid:v4mj9jFW3cci2n75HyyYhsRP+7o false myc tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P40343 uniprotkb:P53622 intact:EBI-20380|uniprotkb:D6W1I1|ensemblfungi:YNR006W intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C psi-mi:vps27_yeast(display_long)|uniprotkb:VPS27(gene name)|psi-mi:VPS27(display_short)|uniprotkb:YNR006W(locus name)|uniprotkb:N2038(orf name)|uniprotkb:DID7(gene name synonym)|uniprotkb:SSV17(gene name synonym)|uniprotkb:VPL23(gene name synonym)|uniprotkb:VPT27(gene name synonym)|uniprotkb:Golgi retention defective protein 11(gene name synonym)|uniprotkb:GRD11(gene name synonym) psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gabriely et al. (2007) pubmed:17101773|imex:IM-19982 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1552283|imex:IM-19982-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005289|refseq:NP_014403.3|ensemblfungi:YNR006W(gene)|ensemblfungi:YNR006W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0140504"(microlipophagy)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|rcsb pdb:1O06|rcsb pdb:1Q0V|rcsb pdb:1Q0W|rcsb pdb:1VFY|rcsb pdb:2KDI|rcsb pdb:2PJW|rcsb pdb:3R42|rcsb pdb:6NJG|dip:DIP-1741N|mint:P40343 refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434 - crc64:76C4501B0EBC9C84 crc64:D3589073106F5570 figure legend:Fig. 5A & 5B|comment:The interaction occured also when Sec28 and Vps23 were deleted.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/11/06 2014/10/16 rogid:5ScB34gSI3x260kAGh/knEWupwA559292 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 intact-crc:BCF7F51D446B7FE2|rigid:X06dMr9XunCDTSjYU0z2LTJqAB4 false green fluorescent protein tag:?-? myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P40343 uniprotkb:P40509 intact:EBI-20380|uniprotkb:D6W1I1|ensemblfungi:YNR006W intact:EBI-4884|uniprotkb:D6VVK8|ensemblfungi:YIL076W psi-mi:vps27_yeast(display_long)|uniprotkb:VPS27(gene name)|psi-mi:VPS27(display_short)|uniprotkb:YNR006W(locus name)|uniprotkb:N2038(orf name)|uniprotkb:DID7(gene name synonym)|uniprotkb:SSV17(gene name synonym)|uniprotkb:VPL23(gene name synonym)|uniprotkb:VPT27(gene name synonym)|uniprotkb:Golgi retention defective protein 11(gene name synonym)|uniprotkb:GRD11(gene name synonym) psi-mi:cope_yeast(display_long)|uniprotkb:SEC28(gene name)|psi-mi:SEC28(display_short)|uniprotkb:YIL076W(locus name)|uniprotkb:Epsilon-coat protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gabriely et al. (2007) pubmed:17101773|imex:IM-19982 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1552310|imex:IM-19982-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005289|refseq:NP_014403.3|ensemblfungi:YNR006W(gene)|ensemblfungi:YNR006W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0140504"(microlipophagy)|go:"GO:1903319"(positive regulation of protein maturation)|go:"GO:1904669"(ATP export)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|rcsb pdb:1O06|rcsb pdb:1Q0V|rcsb pdb:1Q0W|rcsb pdb:1VFY|rcsb pdb:2KDI|rcsb pdb:2PJW|rcsb pdb:3R42|rcsb pdb:6NJG|dip:DIP-1741N|mint:P40343 refseq:NP_012189.2|sgd:S000001338|dip:DIP-4711N|mint:P40509|ensemblfungi:YIL076W(gene)|ensemblfungi:YIL076W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006901"(vesicle coating)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR006822(Coatomer, epsilon subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434 - crc64:76C4501B0EBC9C84 crc64:95ACA8BB647817DB figure legend:Fig. 5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/11/06 2014/10/16 rogid:5ScB34gSI3x260kAGh/knEWupwA559292 rogid:mESavZmt7IyCa/6WZstYCYgXlcM559292 intact-crc:6D50E14ADB27C28A|rigid:v4mj9jFW3cci2n75HyyYhsRP+7o false myc tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)