#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O70343 uniprotkb:Q09472 intact:EBI-1371053|uniprotkb:L0AM20|uniprotkb:L0AN96|uniprotkb:L0APB0|uniprotkb:Q3UP72|ensembl:ENSMUSP00000117040 intact:EBI-447295|intact:EBI-3908041|uniprotkb:B1AKC2|intact:EBI-28987257|ensembl:ENSP00000263253 psi-mi:prgc1_mouse(display_long)|uniprotkb:Ppargc1a(gene name)|psi-mi:Ppargc1a(display_short)|uniprotkb:Pgc1(gene name synonym)|uniprotkb:Pgc1a(gene name synonym)|uniprotkb:Ppargc1(gene name synonym) psi-mi:ep300_human(display_long)|uniprotkb:Histone butyryltransferase p300(gene name synonym)|uniprotkb:Histone crotonyltransferase p300(gene name synonym)|uniprotkb:Protein propionyltransferase p300(gene name synonym)|uniprotkb:EP300(gene name)|psi-mi:EP300(display_short)|uniprotkb:P300(gene name synonym)|uniprotkb:E1A-associated protein p300(gene name synonym)|uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym)|uniprotkb:Protein lactyltransferas p300(gene name synonym) psi-mi:"MI:0091"(chromatography technology) Cooper et al. (2006) pubmed:17050673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1371067 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032930.1|dip:DIP-38447N|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002021"(response to dietary excess)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0009409"(response to cold)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014823"(response to activity)|go:"GO:0014850"(response to muscle activity)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0021549"(cerebellum development)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030900"(forebrain development)|ensembl:ENSMUST00000132734(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043201"(response to leucine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051552"(flavone metabolic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071250"(cellular response to nitrite)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0031325"(positive regulation of cellular metabolic process)|ensembl:ENSMUSG00000029167(gene)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071873"(response to norepinephrine)|go:"GO:0090258"(negative regulation of mitochondrial fission)|go:"GO:0097009"(energy homeostasis)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901558"(response to metformin)|go:"GO:1901857"(positive regulation of cellular respiration)|go:"GO:1901860"(positive regulation of mitochondrial DNA metabolic process)|go:"GO:1901863"(positive regulation of muscle tissue development)|go:"GO:1904635"(positive regulation of glomerular visceral epithelial cell apoptotic process)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1904639"(cellular response to resveratrol)|go:"GO:1904640"(response to methionine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:2000184"(positive regulation of progesterone biosynthetic process)|go:"GO:2000272"(negative regulation of signaling receptor activity)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034605|interpro:IPR034625|interpro:IPR034833|interpro:IPR035979|rcsb pdb:3F7D refseq:NP_001420.2|ensembl:ENSP00000263253|dip:DIP-257N|go:"GO:0140068"(histone crotonyltransferase activity)|go:"GO:0140069"(histone butyryltransferase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|mint:Q09472|rcsb pdb:1L3E|rcsb pdb:1P4Q|rcsb pdb:2K8F|rcsb pdb:2MH0|rcsb pdb:2MZD|rcsb pdb:3BIY|rcsb pdb:3I3J|rcsb pdb:3IO2|go:"GO:0140067"(peptidyl-lysine butyrylation)|rcsb pdb:3P57|rcsb pdb:3T92|rcsb pdb:4PZR|rcsb pdb:4PZS|rcsb pdb:4PZT|rcsb pdb:5BT3|rcsb pdb:5KJ2|rcsb pdb:5LKT|rcsb pdb:5LKU|rcsb pdb:5LKX|rcsb pdb:5LKZ|rcsb pdb:5LPK|rcsb pdb:5LPM|rcsb pdb:5NU5|rcsb pdb:5XZC|rcsb pdb:6DS6|rcsb pdb:6FGN|rcsb pdb:6FGS|rcsb pdb:6GYR|rcsb pdb:6GYT|rcsb pdb:6K4N|rcsb pdb:6PF1|rcsb pdb:6PGU|rcsb pdb:6V8B|rcsb pdb:6V8K|rcsb pdb:6V8N|rcsb pdb:6V90|rcsb pdb:7LJE|reactome:R-HSA-1234158|reactome:R-HSA-1368082|reactome:R-HSA-156711|reactome:R-HSA-1912408|reactome:R-HSA-1989781|reactome:R-HSA-201722|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3134973|reactome:R-HSA-3214847|reactome:R-HSA-3371568|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-5250924|reactome:R-HSA-5617472|reactome:R-HSA-5621575|reactome:R-HSA-5689901|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-6804758|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-8866907|reactome:R-HSA-8936459|reactome:R-HSA-8939243|reactome:R-HSA-8941856|reactome:R-HSA-8941858|reactome:R-HSA-8951936|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9031628|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-9614657|reactome:R-HSA-9616222|reactome:R-HSA-9617629|reactome:R-HSA-9707616|rcsb pdb:4BHW|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENSG00000100393(gene)|ensembl:ENST00000263253(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001756"(somitogenesis)|go:"GO:0001966"(thigmotaxis)|go:"GO:0002039"(p53 binding)|go:"GO:0002209"(behavioral defense response)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007611"(learning or memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030324"(lung development)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034212"(peptide N-acetyltransferase activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006473"(protein acetylation)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0006915"(apoptotic process)|go:"GO:0036268"(swimming)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043627"(response to estrogen)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0061920"(protein propionyltransferase activity)|go:"GO:0061921"(peptidyl-lysine propionylation)|go:"GO:0090043"(regulation of tubulin deacetylation)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0106226"(peptide 2-hydroxyisobutyryltransferase activity)|go:"GO:0120301"(histone lactyltransferase activity)|go:"GO:0140065"(peptide butyryltransferase activity)|go:"GO:0140066"(peptidyl-lysine crotonylation)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response) go:"GO:0005634"(nucleus) - - figure legend:1 taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/07/17 2014/10/16 rogid:2Wp1E+BjMMAFehxqNJGcrqjg1IY10090 rogid:7XzMU6kWdFN0GiLox7RamD9pZeM9606 intact-crc:4FEBEB6029ABA3BB|rigid:1Z3Bzvuslj7N0/eBeOv1+AEVgBE false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O70343 uniprotkb:P46940 intact:EBI-1371053|uniprotkb:L0AM20|uniprotkb:L0AN96|uniprotkb:L0APB0|uniprotkb:Q3UP72|ensembl:ENSMUSP00000117040 intact:EBI-297509|ensembl:ENSP00000268182|uniprotkb:A7MBM3 psi-mi:prgc1_mouse(display_long)|uniprotkb:Ppargc1a(gene name)|psi-mi:Ppargc1a(display_short)|uniprotkb:Pgc1(gene name synonym)|uniprotkb:Pgc1a(gene name synonym)|uniprotkb:Ppargc1(gene name synonym) psi-mi:iqga1_human(display_long)|uniprotkb:IQGAP1(gene name)|psi-mi:IQGAP1(display_short)|uniprotkb:KIAA0051(gene name synonym)|uniprotkb:p195(gene name synonym) psi-mi:"MI:0091"(chromatography technology) Cooper et al. (2006) pubmed:17050673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1371067 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032930.1|dip:DIP-38447N|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002021"(response to dietary excess)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0009409"(response to cold)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014823"(response to activity)|go:"GO:0014850"(response to muscle activity)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0021549"(cerebellum development)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030900"(forebrain development)|ensembl:ENSMUST00000132734(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043201"(response to leucine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051552"(flavone metabolic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071250"(cellular response to nitrite)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0031325"(positive regulation of cellular metabolic process)|ensembl:ENSMUSG00000029167(gene)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071873"(response to norepinephrine)|go:"GO:0090258"(negative regulation of mitochondrial fission)|go:"GO:0097009"(energy homeostasis)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901558"(response to metformin)|go:"GO:1901857"(positive regulation of cellular respiration)|go:"GO:1901860"(positive regulation of mitochondrial DNA metabolic process)|go:"GO:1901863"(positive regulation of muscle tissue development)|go:"GO:1904635"(positive regulation of glomerular visceral epithelial cell apoptotic process)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1904639"(cellular response to resveratrol)|go:"GO:1904640"(response to methionine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:2000184"(positive regulation of progesterone biosynthetic process)|go:"GO:2000272"(negative regulation of signaling receptor activity)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034605|interpro:IPR034625|interpro:IPR034833|interpro:IPR035979|rcsb pdb:3F7D ensembl:ENSG00000140575(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000268182(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000048(IQ calmodulin-binding region)|go:"GO:0030667"(secretory granule membrane)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:P46940|rcsb pdb:1X0H|rcsb pdb:2RR8|rcsb pdb:3FAY|rcsb pdb:3I6X|rcsb pdb:5L0O|reactome:R-HSA-373753|reactome:R-HSA-381676|reactome:R-HSA-5626467|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_003861.1|dip:DIP-32597N go:"GO:0005634"(nucleus) - - figure legend:1 taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/07/17 2014/10/16 rogid:2Wp1E+BjMMAFehxqNJGcrqjg1IY10090 rogid:nXO2Z6Qn8EQGfziT8dnWz1pbK/w9606 intact-crc:4FEBEB6029ABA3BB|rigid:1Z3Bzvuslj7N0/eBeOv1+AEVgBE false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O70343 uniprotkb:P42704 intact:EBI-1371053|uniprotkb:L0AM20|uniprotkb:L0AN96|uniprotkb:L0APB0|uniprotkb:Q3UP72|ensembl:ENSMUSP00000117040 intact:EBI-1050853|uniprotkb:A0PJE3|uniprotkb:A8K1V1|uniprotkb:Q53PC0|uniprotkb:Q53QN7|uniprotkb:Q96D84|uniprotkb:Q6ZUD8|uniprotkb:Q7Z7A6|ensembl:ENSP00000260665 psi-mi:prgc1_mouse(display_long)|uniprotkb:Ppargc1a(gene name)|psi-mi:Ppargc1a(display_short)|uniprotkb:Pgc1(gene name synonym)|uniprotkb:Pgc1a(gene name synonym)|uniprotkb:Ppargc1(gene name synonym) psi-mi:lpprc_human(display_long)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)|uniprotkb:GP130(gene name synonym)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:LRP130(gene name synonym) psi-mi:"MI:0091"(chromatography technology) Cooper et al. (2006) pubmed:17050673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1371067 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032930.1|dip:DIP-38447N|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002021"(response to dietary excess)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0009409"(response to cold)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014823"(response to activity)|go:"GO:0014850"(response to muscle activity)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0021549"(cerebellum development)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030900"(forebrain development)|ensembl:ENSMUST00000132734(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043201"(response to leucine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051552"(flavone metabolic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071250"(cellular response to nitrite)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0031325"(positive regulation of cellular metabolic process)|ensembl:ENSMUSG00000029167(gene)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071873"(response to norepinephrine)|go:"GO:0090258"(negative regulation of mitochondrial fission)|go:"GO:0097009"(energy homeostasis)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901558"(response to metformin)|go:"GO:1901857"(positive regulation of cellular respiration)|go:"GO:1901860"(positive regulation of mitochondrial DNA metabolic process)|go:"GO:1901863"(positive regulation of muscle tissue development)|go:"GO:1904635"(positive regulation of glomerular visceral epithelial cell apoptotic process)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1904639"(cellular response to resveratrol)|go:"GO:1904640"(response to methionine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:2000184"(positive regulation of progesterone biosynthetic process)|go:"GO:2000272"(negative regulation of signaling receptor activity)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034605|interpro:IPR034625|interpro:IPR034833|interpro:IPR035979|rcsb pdb:3F7D refseq:NP_573566.2|ensembl:ENSG00000138095(gene)|ensembl:ENST00000260665(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:P42704|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|dip:DIP-27543N go:"GO:0005634"(nucleus) - - figure legend:1 taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/07/17 2014/10/16 rogid:2Wp1E+BjMMAFehxqNJGcrqjg1IY10090 rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606 intact-crc:4FEBEB6029ABA3BB|rigid:1Z3Bzvuslj7N0/eBeOv1+AEVgBE false flag tag:n-n|ha tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P42704 uniprotkb:Q9UBK2 intact:EBI-1050853|uniprotkb:A0PJE3|uniprotkb:A8K1V1|uniprotkb:Q53PC0|uniprotkb:Q53QN7|uniprotkb:Q96D84|uniprotkb:Q6ZUD8|uniprotkb:Q7Z7A6|ensembl:ENSP00000260665 intact:EBI-765486|uniprotkb:Q9UN32|uniprotkb:B7Z406|uniprotkb:I3RTT5|uniprotkb:I3RTT6|uniprotkb:I3RTT7|uniprotkb:I3RTT8|uniprotkb:I3RTT9|uniprotkb:G8DM16|uniprotkb:Q4W5M7|uniprotkb:Q3LIG1|intact:EBI-28970000|ensembl:ENSP00000264867 psi-mi:lpprc_human(display_long)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)|uniprotkb:GP130(gene name synonym)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:LRP130(gene name synonym) psi-mi:prgc1_human(display_long)|uniprotkb:Ligand effect modulator 6(gene name synonym)|uniprotkb:PPARGC1A(gene name)|psi-mi:PPARGC1A(display_short)|uniprotkb:LEM6(gene name synonym)|uniprotkb:PGC1(gene name synonym)|uniprotkb:PGC1A(gene name synonym)|uniprotkb:PPARGC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cooper et al. (2006) pubmed:17050673 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1371136 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_573566.2|ensembl:ENSG00000138095(gene)|ensembl:ENST00000260665(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:P42704|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|dip:DIP-27543N ensembl:ENSP00000264867|ensembl:ENST00000506055|ensembl:ENSP00000423075|ensembl:ENST00000513205|ensembl:ENSP00000421632|ensembl:ENST00000613098|ensembl:ENSP00000481498|refseq:XP_011512073.1|refseq:NP_001317681.1|refseq:NP_001317682.1|refseq:NP_037393.1|refseq:NP_001317680.1|dip:DIP-38449N|ensembl:ENSG00000109819(gene)|ensembl:ENST00000264867(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002021"(response to dietary excess)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006397"(mRNA processing)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0007586"(digestion)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0009409"(response to cold)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014850"(response to muscle activity)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0021549"(cerebellum development)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030900"(forebrain development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043201"(response to leucine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045333"(cellular respiration)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051552"(flavone metabolic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071250"(cellular response to nitrite)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071873"(response to norepinephrine)|go:"GO:0090258"(negative regulation of mitochondrial fission)|go:"GO:0097009"(energy homeostasis)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901558"(response to metformin)|go:"GO:1901857"(positive regulation of cellular respiration)|go:"GO:1901860"(positive regulation of mitochondrial DNA metabolic process)|go:"GO:1901863"(positive regulation of muscle tissue development)|go:"GO:1904635"(positive regulation of glomerular visceral epithelial cell apoptotic process)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1904639"(cellular response to resveratrol)|go:"GO:1904640"(response to methionine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:2000184"(positive regulation of progesterone biosynthetic process)|go:"GO:2000272"(negative regulation of signaling receptor activity)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034605|interpro:IPR034625|interpro:IPR034833|interpro:IPR035979|mint:Q9UBK2|rcsb pdb:1XB7|rcsb pdb:3B1M|rcsb pdb:3CS8|rcsb pdb:3D24|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:4QJR|rcsb pdb:4QK4|rcsb pdb:5Q0I|rcsb pdb:5UNJ|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6FZF|rcsb pdb:6FZP|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6K0T|rcsb pdb:6KXX|rcsb pdb:6KXY|rcsb pdb:6LN4|rcsb pdb:6MS7|rcsb pdb:6NWK|rcsb pdb:6NWL|rcsb pdb:6T1V|rcsb pdb:6W9K|rcsb pdb:6W9L|rcsb pdb:7E2E|rcsb pdb:7KHT|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2151209|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-8939902|reactome:R-HSA-9615017|rcsb pdb:5TWO|reactome:R-HSA-9707616 go:"GO:0005634"(nucleus) - - figure legend:1C taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2007/07/17 2014/10/16 rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606 rogid:kZHn8pBS+XDQNNMV7vwuyaxnquI9606 intact-crc:6988589D465F82AB|rigid:xspWGZoSisGeD1JZwlkR8wM7rGE false - flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P42704 uniprotkb:Q9UBK2 intact:EBI-1050853|uniprotkb:A0PJE3|uniprotkb:A8K1V1|uniprotkb:Q53PC0|uniprotkb:Q53QN7|uniprotkb:Q96D84|uniprotkb:Q6ZUD8|uniprotkb:Q7Z7A6|ensembl:ENSP00000260665 intact:EBI-765486|uniprotkb:Q9UN32|uniprotkb:B7Z406|uniprotkb:I3RTT5|uniprotkb:I3RTT6|uniprotkb:I3RTT7|uniprotkb:I3RTT8|uniprotkb:I3RTT9|uniprotkb:G8DM16|uniprotkb:Q4W5M7|uniprotkb:Q3LIG1|intact:EBI-28970000|ensembl:ENSP00000264867 psi-mi:lpprc_human(display_long)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)|uniprotkb:GP130(gene name synonym)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:LRP130(gene name synonym) psi-mi:prgc1_human(display_long)|uniprotkb:Ligand effect modulator 6(gene name synonym)|uniprotkb:PPARGC1A(gene name)|psi-mi:PPARGC1A(display_short)|uniprotkb:LEM6(gene name synonym)|uniprotkb:PGC1(gene name synonym)|uniprotkb:PGC1A(gene name synonym)|uniprotkb:PPARGC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cooper et al. (2006) pubmed:17050673 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1371150 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_573566.2|ensembl:ENSG00000138095(gene)|ensembl:ENST00000260665(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:P42704|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|dip:DIP-27543N ensembl:ENSP00000264867|ensembl:ENST00000506055|ensembl:ENSP00000423075|ensembl:ENST00000513205|ensembl:ENSP00000421632|ensembl:ENST00000613098|ensembl:ENSP00000481498|refseq:XP_011512073.1|refseq:NP_001317681.1|refseq:NP_001317682.1|refseq:NP_037393.1|refseq:NP_001317680.1|dip:DIP-38449N|ensembl:ENSG00000109819(gene)|ensembl:ENST00000264867(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002021"(response to dietary excess)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006397"(mRNA processing)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0007586"(digestion)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0009409"(response to cold)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014850"(response to muscle activity)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0021549"(cerebellum development)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030900"(forebrain development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043201"(response to leucine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045333"(cellular respiration)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051552"(flavone metabolic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071250"(cellular response to nitrite)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071873"(response to norepinephrine)|go:"GO:0090258"(negative regulation of mitochondrial fission)|go:"GO:0097009"(energy homeostasis)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901558"(response to metformin)|go:"GO:1901857"(positive regulation of cellular respiration)|go:"GO:1901860"(positive regulation of mitochondrial DNA metabolic process)|go:"GO:1901863"(positive regulation of muscle tissue development)|go:"GO:1904635"(positive regulation of glomerular visceral epithelial cell apoptotic process)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1904639"(cellular response to resveratrol)|go:"GO:1904640"(response to methionine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:2000184"(positive regulation of progesterone biosynthetic process)|go:"GO:2000272"(negative regulation of signaling receptor activity)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034605|interpro:IPR034625|interpro:IPR034833|interpro:IPR035979|mint:Q9UBK2|rcsb pdb:1XB7|rcsb pdb:3B1M|rcsb pdb:3CS8|rcsb pdb:3D24|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:4QJR|rcsb pdb:4QK4|rcsb pdb:5Q0I|rcsb pdb:5UNJ|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6FZF|rcsb pdb:6FZP|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6K0T|rcsb pdb:6KXX|rcsb pdb:6KXY|rcsb pdb:6LN4|rcsb pdb:6MS7|rcsb pdb:6NWK|rcsb pdb:6NWL|rcsb pdb:6T1V|rcsb pdb:6W9K|rcsb pdb:6W9L|rcsb pdb:7E2E|rcsb pdb:7KHT|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2151209|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-8939902|reactome:R-HSA-9615017|rcsb pdb:5TWO|reactome:R-HSA-9707616 go:"GO:0005634"(nucleus) - - figure legend:1C taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2007/07/17 2014/10/16 rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606 rogid:kZHn8pBS+XDQNNMV7vwuyaxnquI9606 intact-crc:FE9CE520ED05FFB3|rigid:xspWGZoSisGeD1JZwlkR8wM7rGE false - flag tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q6PB66 uniprotkb:O70343 intact:EBI-1371262|uniprotkb:Q8K4V0|uniprotkb:Q9CRX4|ensembl:ENSMUSP00000107927 intact:EBI-1371053|uniprotkb:L0AM20|uniprotkb:L0AN96|uniprotkb:L0APB0|uniprotkb:Q3UP72|ensembl:ENSMUSP00000117040 psi-mi:lpprc_mouse(display_long)|uniprotkb:Lrpprc(gene name)|psi-mi:Lrpprc(display_short)|uniprotkb:Lrp130(gene name synonym)|uniprotkb:130 kDa leucine-rich protein(gene name synonym) psi-mi:prgc1_mouse(display_long)|uniprotkb:Ppargc1a(gene name)|psi-mi:Ppargc1a(display_short)|uniprotkb:Pgc1(gene name synonym)|uniprotkb:Pgc1a(gene name synonym)|uniprotkb:Ppargc1(gene name synonym) psi-mi:"MI:0096"(pull down) Cooper et al. (2006) pubmed:17050673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-1371242 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_082509.2|ensembl:ENSMUSG00000024120(gene)|ensembl:ENSMUST00000112308(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|reactome:R-MMU-611105|reactome:R-MMU-9707564|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:Q6PB66|reactome:R-MMU-5628897|go:"GO:0005634"(nucleus) refseq:NP_032930.1|dip:DIP-38447N|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002021"(response to dietary excess)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0009409"(response to cold)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014823"(response to activity)|go:"GO:0014850"(response to muscle activity)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0021549"(cerebellum development)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030900"(forebrain development)|ensembl:ENSMUST00000132734(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043201"(response to leucine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051552"(flavone metabolic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071250"(cellular response to nitrite)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0031325"(positive regulation of cellular metabolic process)|ensembl:ENSMUSG00000029167(gene)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071873"(response to norepinephrine)|go:"GO:0090258"(negative regulation of mitochondrial fission)|go:"GO:0097009"(energy homeostasis)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901558"(response to metformin)|go:"GO:1901857"(positive regulation of cellular respiration)|go:"GO:1901860"(positive regulation of mitochondrial DNA metabolic process)|go:"GO:1901863"(positive regulation of muscle tissue development)|go:"GO:1904635"(positive regulation of glomerular visceral epithelial cell apoptotic process)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1904639"(cellular response to resveratrol)|go:"GO:1904640"(response to methionine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:2000184"(positive regulation of progesterone biosynthetic process)|go:"GO:2000272"(negative regulation of signaling receptor activity)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034605|interpro:IPR034625|interpro:IPR034833|interpro:IPR035979|rcsb pdb:3F7D - - - figure legend:2A and B|comment:Lrpprc Ala353Val mutation did not affect the interaction. taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/07/17 2014/10/16 rogid:wNo59nF0OqIHfnoUrxN10z7YIGM10090 rogid:2Wp1E+BjMMAFehxqNJGcrqjg1IY10090 intact-crc:339AD5A55A04556A|rigid:q9R/SuxSLZrCVE1YFZiwf1u/g2o false 35s radiolabel:?-?|binding-associated region:1-476 flag tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O70343 uniprotkb:Q6PB66 intact:EBI-1371053|uniprotkb:L0AM20|uniprotkb:L0AN96|uniprotkb:L0APB0|uniprotkb:Q3UP72|ensembl:ENSMUSP00000117040 intact:EBI-1371262|uniprotkb:Q8K4V0|uniprotkb:Q9CRX4|ensembl:ENSMUSP00000107927 psi-mi:prgc1_mouse(display_long)|uniprotkb:Ppargc1a(gene name)|psi-mi:Ppargc1a(display_short)|uniprotkb:Pgc1(gene name synonym)|uniprotkb:Pgc1a(gene name synonym)|uniprotkb:Ppargc1(gene name synonym) psi-mi:lpprc_mouse(display_long)|uniprotkb:Lrpprc(gene name)|psi-mi:Lrpprc(display_short)|uniprotkb:Lrp130(gene name synonym)|uniprotkb:130 kDa leucine-rich protein(gene name synonym) psi-mi:"MI:0096"(pull down) Cooper et al. (2006) pubmed:17050673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-1371285 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032930.1|dip:DIP-38447N|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002021"(response to dietary excess)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0009409"(response to cold)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014823"(response to activity)|go:"GO:0014850"(response to muscle activity)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0021549"(cerebellum development)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030900"(forebrain development)|ensembl:ENSMUST00000132734(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043201"(response to leucine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051552"(flavone metabolic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071250"(cellular response to nitrite)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0031325"(positive regulation of cellular metabolic process)|ensembl:ENSMUSG00000029167(gene)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071873"(response to norepinephrine)|go:"GO:0090258"(negative regulation of mitochondrial fission)|go:"GO:0097009"(energy homeostasis)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901558"(response to metformin)|go:"GO:1901857"(positive regulation of cellular respiration)|go:"GO:1901860"(positive regulation of mitochondrial DNA metabolic process)|go:"GO:1901863"(positive regulation of muscle tissue development)|go:"GO:1904635"(positive regulation of glomerular visceral epithelial cell apoptotic process)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1904639"(cellular response to resveratrol)|go:"GO:1904640"(response to methionine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:2000184"(positive regulation of progesterone biosynthetic process)|go:"GO:2000272"(negative regulation of signaling receptor activity)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034605|interpro:IPR034625|interpro:IPR034833|interpro:IPR035979|rcsb pdb:3F7D refseq:NP_082509.2|ensembl:ENSMUSG00000024120(gene)|ensembl:ENSMUST00000112308(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|reactome:R-MMU-611105|reactome:R-MMU-9707564|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:Q6PB66|reactome:R-MMU-5628897|go:"GO:0005634"(nucleus) - - - figure legend:2C taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/07/17 2014/10/16 rogid:2Wp1E+BjMMAFehxqNJGcrqjg1IY10090 rogid:wNo59nF0OqIHfnoUrxN10z7YIGM10090 intact-crc:84457A3ABD4FDF5C|rigid:q9R/SuxSLZrCVE1YFZiwf1u/g2o false binding-associated region:270-400|binding-associated region:1-180 tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VHJ7 uniprotkb:Q6PB66 intact:EBI-1371306|uniprotkb:Q8C1C0|ensembl:ENSMUSP00000074771 intact:EBI-1371262|uniprotkb:Q8K4V0|uniprotkb:Q9CRX4|ensembl:ENSMUSP00000107927 psi-mi:prgc2_mouse(display_long)|uniprotkb:Ppargc1b(gene name)|psi-mi:Ppargc1b(display_short)|uniprotkb:Errl1(gene name synonym)|uniprotkb:Pgc1(gene name synonym)|uniprotkb:Pgc1b(gene name synonym)|uniprotkb:Ppargc1(gene name synonym)|uniprotkb:ERR ligand 1(gene name synonym) psi-mi:lpprc_mouse(display_long)|uniprotkb:Lrpprc(gene name)|psi-mi:Lrpprc(display_short)|uniprotkb:Lrp130(gene name synonym)|uniprotkb:130 kDa leucine-rich protein(gene name synonym) psi-mi:"MI:0096"(pull down) Cooper et al. (2006) pubmed:17050673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1371302 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_573512.1|ensembl:ENSMUSG00000033871(gene)|ensembl:ENSMUST00000075299(transcript)|go:"GO:0001503"(ossification)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0007015"(actin filament organization)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050682"(AF-2 domain binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034177|interpro:IPR034605|interpro:IPR034621|interpro:IPR035979 refseq:NP_082509.2|ensembl:ENSMUSG00000024120(gene)|ensembl:ENSMUST00000112308(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|reactome:R-MMU-611105|reactome:R-MMU-9707564|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:Q6PB66|reactome:R-MMU-5628897|go:"GO:0005634"(nucleus) - - - figure legend:2D taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/07/17 2014/10/16 rogid:zRfLVbrB+jLp8s7PAHZCsL7x0Mw10090 rogid:wNo59nF0OqIHfnoUrxN10z7YIGM10090 intact-crc:746399F8CC3E7840|rigid:I3tPXzMaP6NUJ7yTo1WdeWQtAiU false 35s radiolabel:?-? tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9R1E0 uniprotkb:Q6PB66 intact:EBI-1371343|uniprotkb:Q9JJW4|ensembl:ENSMUSP00000055308 intact:EBI-1371262|uniprotkb:Q8K4V0|uniprotkb:Q9CRX4|ensembl:ENSMUSP00000107927 psi-mi:foxo1_mouse(display_long)|uniprotkb:Foxo1(gene name)|psi-mi:Foxo1(display_short)|uniprotkb:Fkhr(gene name synonym)|uniprotkb:Foxo1a(gene name synonym)|uniprotkb:Forkhead box protein O1A(gene name synonym)|uniprotkb:Forkhead in rhabdomyosarcoma(gene name synonym) psi-mi:lpprc_mouse(display_long)|uniprotkb:Lrpprc(gene name)|psi-mi:Lrpprc(display_short)|uniprotkb:Lrp130(gene name synonym)|uniprotkb:130 kDa leucine-rich protein(gene name synonym) psi-mi:"MI:0096"(pull down) Cooper et al. (2006) pubmed:17050673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1371337 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062713.2|ensembl:ENSMUSG00000044167(gene)|ensembl:ENSMUST00000053764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030154"(cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|reactome:R-MMU-5687128|reactome:R-MMU-9614399|reactome:R-MMU-9617629|reactome:R-MMU-9617828|reactome:R-MMU-211163|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070166"(enamel mineralization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1902617"(response to fluoride)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032067|interpro:IPR032068|interpro:IPR036388|interpro:IPR036390|mint:Q9R1E0|reactome:R-MMU-198693 refseq:NP_082509.2|ensembl:ENSMUSG00000024120(gene)|ensembl:ENSMUST00000112308(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|reactome:R-MMU-611105|reactome:R-MMU-9707564|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:Q6PB66|reactome:R-MMU-5628897|go:"GO:0005634"(nucleus) - - - figure legend:6C taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/07/17 2014/10/16 rogid:FZARINw0mWPO0HuwqULfIigXL2M10090 rogid:wNo59nF0OqIHfnoUrxN10z7YIGM10090 intact-crc:EB57BBE1C9D37AD7|rigid:ObEH4JaRRaqfbVhwph8ymGynMkw false - myc tag:c-c|tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9R1E0 uniprotkb:Q6PB66 intact:EBI-1371343|uniprotkb:Q9JJW4|ensembl:ENSMUSP00000055308 intact:EBI-1371262|uniprotkb:Q8K4V0|uniprotkb:Q9CRX4|ensembl:ENSMUSP00000107927 psi-mi:foxo1_mouse(display_long)|uniprotkb:Foxo1(gene name)|psi-mi:Foxo1(display_short)|uniprotkb:Fkhr(gene name synonym)|uniprotkb:Foxo1a(gene name synonym)|uniprotkb:Forkhead box protein O1A(gene name synonym)|uniprotkb:Forkhead in rhabdomyosarcoma(gene name synonym) psi-mi:lpprc_mouse(display_long)|uniprotkb:Lrpprc(gene name)|psi-mi:Lrpprc(display_short)|uniprotkb:Lrp130(gene name synonym)|uniprotkb:130 kDa leucine-rich protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cooper et al. (2006) pubmed:17050673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1371605 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062713.2|ensembl:ENSMUSG00000044167(gene)|ensembl:ENSMUST00000053764(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001568"(blood vessel development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030154"(cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|reactome:R-MMU-5687128|reactome:R-MMU-9614399|reactome:R-MMU-9617629|reactome:R-MMU-9617828|reactome:R-MMU-211163|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070166"(enamel mineralization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1902617"(response to fluoride)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032067|interpro:IPR032068|interpro:IPR036388|interpro:IPR036390|mint:Q9R1E0|reactome:R-MMU-198693 refseq:NP_082509.2|ensembl:ENSMUSG00000024120(gene)|ensembl:ENSMUST00000112308(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|reactome:R-MMU-611105|reactome:R-MMU-9707564|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:Q6PB66|reactome:R-MMU-5628897|go:"GO:0005634"(nucleus) go:"GO:0005634"(nucleus) - - figure legend:6D taxid:10090(mouse-h2_35)|taxid:10090(Mus musculus H2.35 hepatocyte) - 2007/07/17 2014/10/16 rogid:FZARINw0mWPO0HuwqULfIigXL2M10090 rogid:wNo59nF0OqIHfnoUrxN10z7YIGM10090 intact-crc:6E237D887E1AF29F|rigid:ObEH4JaRRaqfbVhwph8ymGynMkw false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)