#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P06536 uniprotkb:Q62667 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-918333 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:mvp_rat(display_long)|uniprotkb:Mvp(gene name)|psi-mi:Mvp(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:70932|refseq:NP_073206.2|dip:DIP-29532N|reactome:R-RNO-6798695|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008283"(cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0072376"(protein activation cascade)|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR021870|interpro:IPR036013|interpro:IPR039059|interpro:IPR040989|interpro:IPR041134|interpro:IPR041136|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|rcsb pdb:2QZV|rcsb pdb:4HL8|rcsb pdb:4V60|rcsb pdb:6BP7|rcsb pdb:6BP8 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:2E2MhC4ZNFoYaCO9k6yK3IdOz4s10116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:Q7TQN4 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-1187180|ensembl:ENSRNOP00000044552 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:q7tqn4_rat(display_long)|uniprotkb:nos2(gene name synonym)|uniprotkb:rCG_48632(orf name)|uniprotkb:Rela(gene name)|psi-mi:Rela(display_short)|uniprotkb:RelA(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:727889|refseq:NP_954888.1|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|reactome:R-RNO-1169091|reactome:R-RNO-1810476|reactome:R-RNO-3134963|reactome:R-RNO-3214841|reactome:R-RNO-445989|reactome:R-RNO-448706|reactome:R-RNO-4755510|reactome:R-RNO-5621575|reactome:R-RNO-933542|ensembl:ENSRNOG00000030888(gene)|ensembl:ENSRNOT00000045233(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009617"(response to bacterium)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0001889"(liver development)|dip:DIP-38953N psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:1OAcCiqhkrmEeOLfVoUKJdel2/Y10116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:P34058 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-917279|uniprotkb:Q1PSW2|uniprotkb:Q66H55|uniprotkb:Q68GV5|uniprotkb:Q9QWC6|ensembl:ENSRNOP00000026920 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:hs90b_rat(display_long)|uniprotkb:Heat shock 84 kDa(gene name synonym)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84(gene name synonym)|uniprotkb:Hspcb(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:1303075|refseq:NP_001004082.3|ensembl:ENSRNOG00000019834(gene)|ensembl:ENSRNOT00000026920(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P34058|reactome:R-RNO-168928|reactome:R-RNO-2029482|reactome:R-RNO-3371497|reactome:R-RNO-3371511|reactome:R-RNO-3371568|reactome:R-RNO-3371571|reactome:R-RNO-399954|reactome:R-RNO-6798695|reactome:R-RNO-844456|reactome:R-RNO-8852276|reactome:R-RNO-8937144|reactome:R-RNO-8939211|reactome:R-RNO-9013418|reactome:R-RNO-9018519 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:5/MXDESVXdwuWna0s87Ap19aLMA10116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:P41034 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-1187265|ensembl:ENSRNOP00000009611 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:ttpa_rat(display_long)|uniprotkb:Ttpa(gene name)|psi-mi:Ttpa(display_short)|uniprotkb:Tpp1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:3915|refseq:NP_037180.1|go:"GO:0001890"(placenta development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007584"(response to nutrient)|go:"GO:0008431"(vitamin E binding)|go:"GO:0009268"(response to pH)|go:"GO:0009636"(response to toxic substance)|go:"GO:0019842"(vitamin binding)|go:"GO:0032502"(developmental process)|go:"GO:0042360"(vitamin E metabolic process)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0051180"(vitamin transport)|go:"GO:0051452"(intracellular pH reduction)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0090212"(negative regulation of establishment of blood-brain barrier)|go:"GO:0120009"(intermembrane lipid transfer)|go:"GO:0120013"(lipid transfer activity)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|go:"GO:1902936"(phosphatidylinositol bisphosphate binding)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR011074(Phosphatidylinositol transfer protein-like, N-terminal)|interpro:IPR036273|interpro:IPR036865|reactome:R-RNO-8877627|ensembl:ENSRNOT00000009611(transcript)|ensembl:ENSRNOG00000007139(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:TNWPVPm+PTDuM6dYPqW4phdhfMA10116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:Q64620 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-1187315|uniprotkb:Q6AZ47|ensembl:ENSRNOP00000021176 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:ppp6_rat(display_long)|uniprotkb:Protein phosphatase V(gene name synonym)|uniprotkb:Ppp6c(gene name)|psi-mi:Ppp6c(display_short)|uniprotkb:Ppv(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:708460|refseq:NP_598273.2|ensembl:ENSRNOG00000015145(gene)|ensembl:ENSRNOT00000021176(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:Q64620|reactome:R-RNO-171319|reactome:R-RNO-204005 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:R0jsZoqJLoRaSNMNCLRkQ40CC+o10116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:P02770 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-1187193|uniprotkb:P11382|uniprotkb:Q5U3X3 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:albu_rat(display_long)|uniprotkb:Alb(gene name)|psi-mi:Alb(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:2085|refseq:NP_599153.2|interpro:IPR000264(Serum albumin)|interpro:IPR020858|interpro:IPR020857|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR021177|go:"GO:0003677"(DNA binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007584"(response to nutrient)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010033"(response to organic substance)|go:"GO:0015643"(toxic substance binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042311"(vasodilation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046689"(response to mercury ion)|go:"GO:0051087"(chaperone binding)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070541"(response to platinum ion)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1903981"(enterobactin binding)|go:"GO:0140272"(exogenous protein binding)|reactome:R-RNO-114608|reactome:R-RNO-159418|reactome:R-RNO-2168880|reactome:R-RNO-381426|reactome:R-RNO-879518|reactome:R-RNO-8957275|reactome:R-RNO-8964058|reactome:R-RNO-189451|reactome:R-RNO-189483|reactome:R-RNO-9707564 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:dyiSsfiO93bE9An8bo1rCmcS45o10116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:Q99MZ8 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-1187247|uniprotkb:Q499R9|ensembl:ENSRNOP00000005522 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:lasp1_rat(display_long)|uniprotkb:Lasp1(gene name)|psi-mi:Lasp1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:68408|refseq:NP_116002.1|ensembl:ENSRNOG00000004132(gene)|ensembl:ENSRNOT00000005522(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006811"(ion transport)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR035630|interpro:IPR036028 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:m3WpP6O3EOMhE0vSIuNiZmqTLp410116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:P24090 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-1187298|uniprotkb:Q5BKD2 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:fetua_rat(display_long)|uniprotkb:Fetuin-A(gene name synonym)|uniprotkb:Glycoprotein PP63(gene name synonym)|uniprotkb:59 kDa bone sialic acid-containing protein(gene name synonym)|uniprotkb:Ahsg(gene name)|psi-mi:Ahsg(display_short)|uniprotkb:Fetua(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:2075|refseq:NP_037030.1|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001363(Proteinase inhibitor I25C, fetuin, conserved site)|interpro:IPR025760|go:"GO:0001503"(ossification)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008584"(male gonad development)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030294"(receptor signaling protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0006953"(acute-phase response) psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:NwNdomt3sxkAeX/mKrvaghPW9e810116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:Q63716 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-918674|ensembl:ENSRNOP00000023132 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:prdx1_rat(display_long)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Heme-binding 23 kDa protein(gene name synonym)|uniprotkb:HBP23(gene name synonym)|uniprotkb:Prdx1(gene name)|psi-mi:Prdx1(display_short)|uniprotkb:Tdpx2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:620039|refseq:NP_476455.1|ensembl:ENSRNOG00000017194(gene)|ensembl:ENSRNOT00000023132(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000791"(euchromatin)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0020037"(heme binding)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q63716|rcsb pdb:1QQ2|rcsb pdb:2Z9S|reactome:R-RNO-3299685|reactome:R-RNO-5628897 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:6Yx5rIs6p9cg57ePcRAtiWUM7p010116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:O35824 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-1187217 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:dnja2_rat(display_long)|uniprotkb:RDJ2(gene name synonym)|uniprotkb:Dnaja2(gene name)|psi-mi:Dnaja2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|rgd:71001|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR008971(HSP40/DnaJ peptide-binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0018885"(carbon tetrachloride metabolic process)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|reactome:R-RNO-3371497|mint:O35824|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:msgM7nFOH7krpYMCrW4lzOOcAmA10116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:O88801 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-1187324|uniprotkb:O88802|ensembl:ENSRNOP00000070858 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:home2_rat(display_long)|uniprotkb:Cupidin(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 2(gene name synonym)|uniprotkb:Homer2(gene name)|psi-mi:Homer2(display_short)|uniprotkb:Vesl2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:620705|refseq:NP_445761.1|ensembl:ENSRNOG00000061450(gene)|ensembl:ENSRNOT00000087785(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0032426"(stereocilium tip)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048875"(chemical homeostasis within a tissue)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|reactome:R-RNO-6794361|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030425"(dendrite) psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:GlTv3f+uSOfvYEN9xnH1msfLG2o10116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:Q62627 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-1187240 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:pawr_rat(display_long)|uniprotkb:Prostate apoptosis response 4 protein(gene name synonym)|uniprotkb:Transcriptional repressor Par-4-like protein PAWR(gene name synonym)|uniprotkb:Pawr(gene name)|psi-mi:Pawr(display_short)|uniprotkb:Par4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:69065|refseq:NP_277020.1|interpro:IPR026117|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009611"(response to wounding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042986"(positive regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043005"(neuron projection)|go:"GO:0003779"(actin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0060450"(positive regulation of hindgut contraction)|go:"GO:0071306"(cellular response to vitamin E)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090281"(negative regulation of calcium ion import)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:1901082"(positive regulation of relaxation of smooth muscle)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1903238"(positive regulation of leukocyte tethering or rolling)|go:"GO:1904457"(positive regulation of neuronal action potential)|go:"GO:2000391"(positive regulation of neutrophil extravasation)|go:"GO:2000774"(positive regulation of cellular senescence)|rcsb pdb:5FIY psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:wNH2PrL9GaukUQg1Gc+3Q+h0sB010116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:Q3T1L0 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-920934|ensembl:ENSRNOP00000027992 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:a16a1_rat(display_long)|uniprotkb:Aldh16a1(gene name)|psi-mi:Aldh16a1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:1566295|refseq:NP_001028878.1|ensembl:ENSRNOG00000020623(gene)|ensembl:ENSRNOT00000027992(transcript)|go:"GO:0016620"(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)|interpro:IPR011408(Aldehyde dehydrogenase predicted, duplicated region)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal) psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:lED44lBhJ/rLuGpXYDZvQ81H0JU10116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:Q3KRE8 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-349199|ensembl:ENSRNOP00000023582|ensembl:ENSRNOP00000073323|uniprotkb:A3KMR7|uniprotkb:P04691 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:tbb2b_rat(display_long)|uniprotkb:T beta-15(gene name synonym)|uniprotkb:Tubb2b(gene name)|psi-mi:Tubb2b(display_short)|uniprotkb:Tubb2a(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:1309427|refseq:NP_001013908.2|ensembl:ENSRNOG00000017445(gene)|ensembl:ENSRNOT00000023582(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|ensembl:ENSRNOT00000083705(transcript)|reactome:R-RNO-5626467|interpro:IPR017975|interpro:IPR018316|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|interpro:IPR023123|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8955332|interpro:IPR036525|interpro:IPR037103|mint:Q3KRE8|reactome:R-RNO-190840|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3371497|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620924|reactome:R-RNO-983189 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:sluQMryNuOvp6xlV558+agiRwvE10116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:P14480 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-1187259|uniprotkb:Q5I0P7|uniprotkb:Q7TME5|ensembl:ENSRNOP00000009813 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:fibb_rat(display_long)|uniprotkb:Liver regeneration-related protein LRRG036/LRRG043/LRRG189(gene name synonym)|uniprotkb:Fgb(gene name)|psi-mi:Fgb(display_short)|uniprotkb:Ab1-181(orf name)|uniprotkb:Ab1-216(orf name)|uniprotkb:Ac1-581(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:2604|refseq:NP_064456.2|ensembl:ENSRNOG00000007092(gene)|ensembl:ENSRNOT00000009813(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045087"(innate immune response)|go:"GO:0034622"|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037580|reactome:R-RNO-114608|reactome:R-RNO-140875|reactome:R-RNO-216083|reactome:R-RNO-354192|reactome:R-RNO-354194|reactome:R-RNO-372708|reactome:R-RNO-5674135|go:"GO:0070527"(platelet aggregation) psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:594ZUCBmPRLU8b9uGPrEK3hcG5I10116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:P62870 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-918620|uniprotkb:Q63529|uniprotkb:Q80W20|ensembl:ENSRNOP00000072621 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:elob_rat(display_long)|uniprotkb:Elob(gene name)|psi-mi:Elob(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:Tceb2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:621200|refseq:NP_112391.1|ensembl:ENSRNOG00000004814(gene)|ensembl:ENSRNOT00000087768(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:P62870|reactome:R-RNO-112382|reactome:R-RNO-1234176|reactome:R-RNO-674695|reactome:R-RNO-6796648|reactome:R-RNO-75955|reactome:R-RNO-8951664|reactome:R-RNO-9705462|reactome:R-RNO-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:7W4I9AcvS1GK89dMmBOImMYNgLY10116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:P83941 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-398626|uniprotkb:Q63182|ensembl:ENSRNOP00000067410|ensembl:ENSRNOP00000069739|ensembl:ENSRNOP00000071456 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:eloc_rat(display_long)|uniprotkb:Eloc(gene name)|psi-mi:Eloc(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:Stromal membrane-associated protein SMAP1B homolog(gene name synonym)|uniprotkb:Tceb1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:620658|refseq:NP_072115.1|refseq:XP_006237786.1|refseq:NP_001257490.1|refseq:NP_001257491.1|refseq:NP_001257492.1|reactome:R-RNO-674695|reactome:R-RNO-6796648|reactome:R-RNO-75955|reactome:R-RNO-8951664|reactome:R-RNO-9705462|reactome:R-RNO-983168|reactome:R-RNO-1234176|ensembl:ENSRNOG00000031730(gene)|ensembl:ENSRNOT00000050236(transcript)|ensembl:ENSRNOT00000082813(transcript)|ensembl:ENSRNOT00000090313(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:P83941|reactome:R-RNO-112382 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz410116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:P36506 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-1187275|uniprotkb:A0JN15|ensembl:ENSRNOP00000027272 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:mp2k2_rat(display_long)|uniprotkb:ERK activator kinase 2(gene name synonym)|uniprotkb:MAPK/ERK kinase 2(gene name synonym)|uniprotkb:Map2k2(gene name)|psi-mi:Map2k2(display_short)|uniprotkb:Mek2(gene name synonym)|uniprotkb:Mkk2(gene name synonym)|uniprotkb:Prkmk2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:61888|refseq:NP_579817.1|ensembl:ENSRNOG00000020005(gene)|ensembl:ENSRNOT00000027272(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007507"(heart development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030878"(thyroid gland development)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048538"(thymus development)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060502"(epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-RNO-112411|reactome:R-RNO-170968|reactome:R-RNO-445144|reactome:R-RNO-5673000|reactome:R-RNO-5674135|reactome:R-RNO-5674499|go:"GO:0009898"(cytoplasmic side of plasma membrane) psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:aVrt0U6EZMlBr3IVdXH5Bb6d06o10116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:O09171 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-1187287|uniprotkb:Q6AZ06 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:bhmt1_rat(display_long)|uniprotkb:Bhmt(gene name)|psi-mi:Bhmt(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:621496|refseq:NP_110477.1|interpro:IPR017226(Betaine--homocysteine S-methyltransferase, BHMT)|interpro:IPR003726(Homocysteine S-methyltransferase)|rcsb pdb:1UMY|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0006577"(amino-acid betaine metabolic process)|go:"GO:0006579"(amino-acid betaine catabolic process)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047150"(betaine-homocysteine S-methyltransferase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071267"(L-methionine salvage)|interpro:IPR036589|reactome:R-RNO-1614635|reactome:R-RNO-6798163 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:yYDrFBPL+qptvSK5AsOy7rXEeeU10116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:P02692 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-1209448|ensembl:ENSRNOP00000008841 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:fabpl_rat(display_long)|uniprotkb:Fabp1(gene name)|psi-mi:Fabp1(display_short)|uniprotkb:Liver-type fatty acid-binding protein(gene name synonym)|uniprotkb:Squalene- and sterol-carrier protein(gene name synonym)|uniprotkb:Z-protein(gene name synonym)|uniprotkb:p14(gene name synonym)|uniprotkb:Fatty acid-binding protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:2590|refseq:NP_036688.1|ensembl:ENSRNOG00000006675(gene)|ensembl:ENSRNOT00000008840(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016209"(antioxidant activity)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032052"(bile acid binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036094"(small molecule binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045179"(apical cortex)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:0051978"("lysophospholipid:sodium symporter activity")|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR012674(Calycin)|interpro:IPR031259|interpro:IPR031276|rcsb pdb:1LFO|rcsb pdb:2JU3|rcsb pdb:2JU7|rcsb pdb:2JU8|reactome:R-RNO-163560|reactome:R-RNO-189483|reactome:R-RNO-400206|reactome:R-RNO-9707564 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:8Hy751OJC8+vPMhzov3749CU9vM10116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:P68370 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-349571|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q6P6G6|ensembl:ENSRNOP00000075232 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:tba1a_rat(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tuba1(gene name synonym)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:619717|refseq:NP_071634.1|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|ensembl:ENSRNOG00000060728(gene)|ensembl:ENSRNOT00000083156(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68370|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620912|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8854518|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:P01946 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-1209456|uniprotkb:P33583|uniprotkb:Q63243|uniprotkb:Q80XV2|uniprotkb:Q91V15|ensembl:ENSRNOP00000044233 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:hba_rat(display_long)|uniprotkb:Hba1(gene name)|psi-mi:Hba1(display_short)|uniprotkb:Hba-a1(gene name synonym)|uniprotkb:Hemoglobin alpha-1/2 chain(gene name synonym)|uniprotkb:Alpha-1/2-globin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:2782|refseq:NP_001007723.1|refseq:NP_037228.1|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0009617"(response to bacterium)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0045202"(synapse)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0048821"(erythrocyte development)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0098869"(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002338(Haemoglobin, alpha)|interpro:IPR002339(Haemoglobin, pi)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|rcsb pdb:3DHT|rcsb pdb:3HF4|reactome:R-RNO-1237044|reactome:R-RNO-1247673|reactome:R-RNO-2168880|reactome:R-RNO-9707564|reactome:R-RNO-9707616|go:"GO:0001540"(amyloid-beta binding)|ensembl:ENSRNOG00000029886(gene)|ensembl:ENSRNOT00000051483(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:UtEMtpGnzOlmYQ3I9oqtG1dUbNI10116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P06536 uniprotkb:P63036 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-772420|ensembl:ENSRNOP00000010061|uniprotkb:P54102 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:dnja1_rat(display_long)|uniprotkb:DnaJ-like protein 1(gene name synonym)|uniprotkb:Dnaja1(gene name)|psi-mi:Dnaja1(display_short)|uniprotkb:Hsj2(gene name synonym)|uniprotkb:Rdj1(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187343|imex:IM-11850-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 ensembl:ENSRNOG00000007029(gene)|ensembl:ENSRNOT00000010061(transcript)|rgd:620942|refseq:NP_075223.1|refseq:XP_006238161.1|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|reactome:R-RNO-3371497 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Table 2.|comment:"The following proteins were reported as having avarage ratios (non-liganded(nn-activated) over liganded (activated))of standardised spot volumes. P24090 (ratio = 5.84), Q6AYZ1(ratio = 4.17), P06399 (four spots ratio = 4.83, 3.88, 6.37,7.09 ), P63037 (ratio = 11.29), P14480 (4.28), P13832 (two spots ratio = -21.44, -13.40), P62870 (ratio = 5.95) and P27605 (ratio = -13.38)"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:gi42F7LF6CiylXZF4fRg/kuM/s010116 intact-crc:D2E5234E7CCB1C15|rigid:/R4REqqUDYqhIL5C/6Is5l5zSRk false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P04150 uniprotkb:Q62667 intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672 intact:EBI-918333 psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym) psi-mi:mvp_rat(display_long)|uniprotkb:Mvp(gene name)|psi-mi:Mvp(display_short) psi-mi:"MI:0096"(pull down) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1187389|imex:IM-11850-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N rgd:70932|refseq:NP_073206.2|dip:DIP-29532N|reactome:R-RNO-6798695|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008283"(cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0072376"(protein activation cascade)|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR021870|interpro:IPR036013|interpro:IPR039059|interpro:IPR040989|interpro:IPR041134|interpro:IPR041136|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|rcsb pdb:2QZV|rcsb pdb:4HL8|rcsb pdb:4V60|rcsb pdb:6BP7|rcsb pdb:6BP8 psi-mi:"MI:0469"(intact) - - figure legend:2a|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/01/23 2014/10/16 rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606 rogid:2E2MhC4ZNFoYaCO9k6yK3IdOz4s10116 intact-crc:B222F9F59BA760E7|rigid:WukMmb+VEpdrxBG8iUl47i5muGU false 35s radiolabel:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06536 uniprotkb:Q62667 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 intact:EBI-918333 psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:mvp_rat(display_long)|uniprotkb:Mvp(gene name)|psi-mi:Mvp(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187407|imex:IM-11850-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 rgd:70932|refseq:NP_073206.2|dip:DIP-29532N|reactome:R-RNO-6798695|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008283"(cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0072376"(protein activation cascade)|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR021870|interpro:IPR036013|interpro:IPR039059|interpro:IPR040989|interpro:IPR041134|interpro:IPR041136|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|rcsb pdb:2QZV|rcsb pdb:4HL8|rcsb pdb:4V60|rcsb pdb:6BP7|rcsb pdb:6BP8 psi-mi:"MI:0469"(intact) - - figure legend:2b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-htc)|taxid:10116(Rat hepatoma HTC cells) - 2007/01/23 2014/10/16 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 rogid:2E2MhC4ZNFoYaCO9k6yK3IdOz4s10116 intact-crc:249ACE61770F5111|rigid:E+7jbevRxX+aUXy23fpiuYRWpBM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P04150 uniprotkb:Q62667 intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672 intact:EBI-918333 psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym) psi-mi:mvp_rat(display_long)|uniprotkb:Mvp(gene name)|psi-mi:Mvp(display_short) psi-mi:"MI:0018"(two hybrid) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187420|imex:IM-11850-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N rgd:70932|refseq:NP_073206.2|dip:DIP-29532N|reactome:R-RNO-6798695|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008283"(cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0072376"(protein activation cascade)|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR021870|interpro:IPR036013|interpro:IPR039059|interpro:IPR040989|interpro:IPR041134|interpro:IPR041136|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|rcsb pdb:2QZV|rcsb pdb:4HL8|rcsb pdb:4V60|rcsb pdb:6BP7|rcsb pdb:6BP8 psi-mi:"MI:0469"(intact) - - figure legend:2c|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/01/23 2014/10/16 rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606 rogid:2E2MhC4ZNFoYaCO9k6yK3IdOz4s10116 intact-crc:71C66DC2B7DF0686|rigid:WukMmb+VEpdrxBG8iUl47i5muGU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q3T1L0 uniprotkb:P02770 intact:EBI-920934|ensembl:ENSRNOP00000027992 intact:EBI-1187193|uniprotkb:P11382|uniprotkb:Q5U3X3 psi-mi:a16a1_rat(display_long)|uniprotkb:Aldh16a1(gene name)|psi-mi:Aldh16a1(display_short) psi-mi:albu_rat(display_long)|uniprotkb:Alb(gene name)|psi-mi:Alb(display_short) psi-mi:"MI:0276"(blue native page) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187442|imex:IM-11850-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1566295|refseq:NP_001028878.1|ensembl:ENSRNOG00000020623(gene)|ensembl:ENSRNOT00000027992(transcript)|go:"GO:0016620"(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)|interpro:IPR011408(Aldehyde dehydrogenase predicted, duplicated region)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal) rgd:2085|refseq:NP_599153.2|interpro:IPR000264(Serum albumin)|interpro:IPR020858|interpro:IPR020857|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR021177|go:"GO:0003677"(DNA binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007584"(response to nutrient)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010033"(response to organic substance)|go:"GO:0015643"(toxic substance binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042311"(vasodilation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0046689"(response to mercury ion)|go:"GO:0051087"(chaperone binding)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070541"(response to platinum ion)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1903981"(enterobactin binding)|go:"GO:0140272"(exogenous protein binding)|reactome:R-RNO-114608|reactome:R-RNO-159418|reactome:R-RNO-2168880|reactome:R-RNO-381426|reactome:R-RNO-879518|reactome:R-RNO-8957275|reactome:R-RNO-8964058|reactome:R-RNO-189451|reactome:R-RNO-189483|reactome:R-RNO-9707564 psi-mi:"MI:0469"(intact) - - figure legend:Table 2|caution:The authors provide a list of proteins isolated from several separate protein complexes and do not differentiate which proteins were identified in a specific complex. This entry lists the proteins from several protein complexes as set out in Table 2 of the report. Therefore the user should be aware that this entry does not indicate that all of the proteins were found in a single protein complex.|caution:"The participant EBI-1187287(O09171) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:lED44lBhJ/rLuGpXYDZvQ81H0JU10116 rogid:dyiSsfiO93bE9An8bo1rCmcS45o10116 intact-crc:E5C902F44EF3E1D7|rigid:QCYjhfvDJW5Zbdpf+ERGszQDkoM false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q3T1L0 uniprotkb:O09171 intact:EBI-920934|ensembl:ENSRNOP00000027992 intact:EBI-1187287|uniprotkb:Q6AZ06 psi-mi:a16a1_rat(display_long)|uniprotkb:Aldh16a1(gene name)|psi-mi:Aldh16a1(display_short) psi-mi:bhmt1_rat(display_long)|uniprotkb:Bhmt(gene name)|psi-mi:Bhmt(display_short) psi-mi:"MI:0276"(blue native page) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187442|imex:IM-11850-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1566295|refseq:NP_001028878.1|ensembl:ENSRNOG00000020623(gene)|ensembl:ENSRNOT00000027992(transcript)|go:"GO:0016620"(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)|interpro:IPR011408(Aldehyde dehydrogenase predicted, duplicated region)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal) rgd:621496|refseq:NP_110477.1|interpro:IPR017226(Betaine--homocysteine S-methyltransferase, BHMT)|interpro:IPR003726(Homocysteine S-methyltransferase)|rcsb pdb:1UMY|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0006577"(amino-acid betaine metabolic process)|go:"GO:0006579"(amino-acid betaine catabolic process)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047150"(betaine-homocysteine S-methyltransferase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071267"(L-methionine salvage)|interpro:IPR036589|reactome:R-RNO-1614635|reactome:R-RNO-6798163 psi-mi:"MI:0469"(intact) - - figure legend:Table 2|caution:The authors provide a list of proteins isolated from several separate protein complexes and do not differentiate which proteins were identified in a specific complex. This entry lists the proteins from several protein complexes as set out in Table 2 of the report. Therefore the user should be aware that this entry does not indicate that all of the proteins were found in a single protein complex.|caution:"The participant EBI-1187287(O09171) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:lED44lBhJ/rLuGpXYDZvQ81H0JU10116 rogid:yYDrFBPL+qptvSK5AsOy7rXEeeU10116 intact-crc:E5C902F44EF3E1D7|rigid:QCYjhfvDJW5Zbdpf+ERGszQDkoM false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q3T1L0 uniprotkb:P06536 intact:EBI-920934|ensembl:ENSRNOP00000027992 intact:EBI-1187143|uniprotkb:O08624|uniprotkb:Q8R463|uniprotkb:Q8R5J0 psi-mi:a16a1_rat(display_long)|uniprotkb:Aldh16a1(gene name)|psi-mi:Aldh16a1(display_short) psi-mi:gcr_rat(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym) psi-mi:"MI:0276"(blue native page) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187442|imex:IM-11850-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1566295|refseq:NP_001028878.1|ensembl:ENSRNOG00000020623(gene)|ensembl:ENSRNOT00000027992(transcript)|go:"GO:0016620"(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)|interpro:IPR011408(Aldehyde dehydrogenase predicted, duplicated region)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rgd:2741|refseq:NP_036708.2|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009314"(response to radiation)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0014889"(muscle atrophy)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046689"(response to mercury ion)|go:"GO:0048096"|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1GDC|rcsb pdb:1GLU|rcsb pdb:1LAT|rcsb pdb:1R4O|rcsb pdb:1R4R|rcsb pdb:1RGD|rcsb pdb:2GDA|rcsb pdb:3FYL|rcsb pdb:3G6P|rcsb pdb:3G6Q|rcsb pdb:3G6R|rcsb pdb:3G6T|rcsb pdb:3G6U|rcsb pdb:3G8U|rcsb pdb:3G8X|rcsb pdb:3G97|rcsb pdb:3G99|rcsb pdb:3G9I|rcsb pdb:3G9J|rcsb pdb:3G9M|rcsb pdb:3G9O|rcsb pdb:3G9P|dip:DIP-38940N|reactome:R-RNO-3371497|reactome:R-RNO-383280|reactome:R-RNO-4090294 psi-mi:"MI:0469"(intact) - - figure legend:Table 2|caution:The authors provide a list of proteins isolated from several separate protein complexes and do not differentiate which proteins were identified in a specific complex. This entry lists the proteins from several protein complexes as set out in Table 2 of the report. Therefore the user should be aware that this entry does not indicate that all of the proteins were found in a single protein complex.|caution:"The participant EBI-1187287(O09171) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:lED44lBhJ/rLuGpXYDZvQ81H0JU10116 rogid:WIZJZH63iLNQil/EUt7RTXSpE9E10116 intact-crc:E5C902F44EF3E1D7|rigid:QCYjhfvDJW5Zbdpf+ERGszQDkoM false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q3T1L0 uniprotkb:P27605 intact:EBI-920934|ensembl:ENSRNOP00000027992 intact:EBI-917005|uniprotkb:P70469|uniprotkb:Q4KMC5|uniprotkb:Q62926|ensembl:ENSRNOP00000043388|ensembl:ENSRNOP00000062740 psi-mi:a16a1_rat(display_long)|uniprotkb:Aldh16a1(gene name)|psi-mi:Aldh16a1(display_short) psi-mi:hprt_rat(display_long)|uniprotkb:Hprt1(gene name)|psi-mi:Hprt1(display_short)|uniprotkb:Hprt(gene name synonym) psi-mi:"MI:0276"(blue native page) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187442|imex:IM-11850-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1566295|refseq:NP_001028878.1|ensembl:ENSRNOG00000020623(gene)|ensembl:ENSRNOT00000027992(transcript)|go:"GO:0016620"(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)|interpro:IPR011408(Aldehyde dehydrogenase predicted, duplicated region)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal) rgd:2826|refseq:NP_036715.1|refseq:XP_008771881.1|ensembl:ENSRNOG00000031367(gene)|ensembl:ENSRNOG00000048561(gene)|ensembl:ENSRNOT00000045153(transcript)|ensembl:ENSRNOT00000065935(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006168"(adenine salvage)|go:"GO:0006178"(guanine salvage)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0021756"(striatum development)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043103"(hypoxanthine salvage)|go:"GO:0045964"(positive regulation of dopamine metabolic process)|go:"GO:0046038"(GMP catabolic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046083"(adenine metabolic process)|go:"GO:0046100"(hypoxanthine metabolic process)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0052657"(guanine phosphoribosyltransferase activity)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|reactome:R-RNO-74217 psi-mi:"MI:0469"(intact) - - figure legend:Table 2|caution:The authors provide a list of proteins isolated from several separate protein complexes and do not differentiate which proteins were identified in a specific complex. This entry lists the proteins from several protein complexes as set out in Table 2 of the report. Therefore the user should be aware that this entry does not indicate that all of the proteins were found in a single protein complex.|caution:"The participant EBI-1187287(O09171) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:lED44lBhJ/rLuGpXYDZvQ81H0JU10116 rogid:gm0u1QTRqRJVAysCQSvjyv+8ctU10116 intact-crc:E5C902F44EF3E1D7|rigid:QCYjhfvDJW5Zbdpf+ERGszQDkoM false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q3T1L0 uniprotkb:P34058 intact:EBI-920934|ensembl:ENSRNOP00000027992 intact:EBI-917279|uniprotkb:Q1PSW2|uniprotkb:Q66H55|uniprotkb:Q68GV5|uniprotkb:Q9QWC6|ensembl:ENSRNOP00000026920 psi-mi:a16a1_rat(display_long)|uniprotkb:Aldh16a1(gene name)|psi-mi:Aldh16a1(display_short) psi-mi:hs90b_rat(display_long)|uniprotkb:Heat shock 84 kDa(gene name synonym)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84(gene name synonym)|uniprotkb:Hspcb(gene name synonym) psi-mi:"MI:0276"(blue native page) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187442|imex:IM-11850-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1566295|refseq:NP_001028878.1|ensembl:ENSRNOG00000020623(gene)|ensembl:ENSRNOT00000027992(transcript)|go:"GO:0016620"(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)|interpro:IPR011408(Aldehyde dehydrogenase predicted, duplicated region)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal) rgd:1303075|refseq:NP_001004082.3|ensembl:ENSRNOG00000019834(gene)|ensembl:ENSRNOT00000026920(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P34058|reactome:R-RNO-168928|reactome:R-RNO-2029482|reactome:R-RNO-3371497|reactome:R-RNO-3371511|reactome:R-RNO-3371568|reactome:R-RNO-3371571|reactome:R-RNO-399954|reactome:R-RNO-6798695|reactome:R-RNO-844456|reactome:R-RNO-8852276|reactome:R-RNO-8937144|reactome:R-RNO-8939211|reactome:R-RNO-9013418|reactome:R-RNO-9018519 psi-mi:"MI:0469"(intact) - - figure legend:Table 2|caution:The authors provide a list of proteins isolated from several separate protein complexes and do not differentiate which proteins were identified in a specific complex. This entry lists the proteins from several protein complexes as set out in Table 2 of the report. Therefore the user should be aware that this entry does not indicate that all of the proteins were found in a single protein complex.|caution:"The participant EBI-1187287(O09171) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:lED44lBhJ/rLuGpXYDZvQ81H0JU10116 rogid:5/MXDESVXdwuWna0s87Ap19aLMA10116 intact-crc:E5C902F44EF3E1D7|rigid:QCYjhfvDJW5Zbdpf+ERGszQDkoM false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q3T1L0 uniprotkb:Q6PEC4 intact:EBI-920934|ensembl:ENSRNOP00000027992 intact:EBI-919194|ensembl:ENSRNOP00000007676 psi-mi:a16a1_rat(display_long)|uniprotkb:Aldh16a1(gene name)|psi-mi:Aldh16a1(display_short) psi-mi:skp1_rat(display_long)|uniprotkb:Skp1(gene name)|psi-mi:Skp1(display_short)|uniprotkb:Skp1a(gene name synonym)|uniprotkb:S-phase kinase-associated protein 1A(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:p19A(gene name synonym) psi-mi:"MI:0276"(blue native page) Hedman et al. (2006) imex:IM-11850|pubmed:16619302 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1187442|imex:IM-11850-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1566295|refseq:NP_001028878.1|ensembl:ENSRNOG00000020623(gene)|ensembl:ENSRNOT00000027992(transcript)|go:"GO:0016620"(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)|interpro:IPR011408(Aldehyde dehydrogenase predicted, duplicated region)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal) rgd:1359648|refseq:NP_001007609.1|dip:DIP-29863N|ensembl:ENSRNOG00000005828(gene)|ensembl:ENSRNOT00000007676(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|reactome:R-RNO-1169091|reactome:R-RNO-1170546|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2565942|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5676590|reactome:R-RNO-68949|reactome:R-RNO-69231|reactome:R-RNO-8854050|reactome:R-RNO-8951664|reactome:R-RNO-917937|reactome:R-RNO-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table 2|caution:The authors provide a list of proteins isolated from several separate protein complexes and do not differentiate which proteins were identified in a specific complex. This entry lists the proteins from several protein complexes as set out in Table 2 of the report. Therefore the user should be aware that this entry does not indicate that all of the proteins were found in a single protein complex.|caution:"The participant EBI-1187287(O09171) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-liver)|taxid:10116(rattus norvegicus liver) - 2007/01/23 2014/10/16 rogid:lED44lBhJ/rLuGpXYDZvQ81H0JU10116 rogid:qGk720KMKAbBPguy2tmUOZsLxRQ10116 intact-crc:E5C902F44EF3E1D7|rigid:QCYjhfvDJW5Zbdpf+ERGszQDkoM false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry)