#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9EPK5	uniprotkb:Q99593	intact:EBI-1211920|uniprotkb:Q3UQ69|uniprotkb:Q3UQM0|uniprotkb:Q99KI4|ensembl:ENSMUSP00000029380	intact:EBI-297043|uniprotkb:O15301|uniprotkb:Q9Y4I2|ensembl:ENSP00000309913|ensembl:ENSP00000384152|uniprotkb:A6ND77|uniprotkb:Q96TB0	psi-mi:wwtr1_mouse(display_long)|uniprotkb:Wwtr1(gene name)|psi-mi:Wwtr1(display_short)|uniprotkb:Taz(gene name synonym)|uniprotkb:Transcriptional coactivator with PDZ-binding motif(gene name synonym)	psi-mi:tbx5_human(display_long)|uniprotkb:TBX5(gene name)|psi-mi:TBX5(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Murakami et al. (2005)	pubmed:16332960|imex:IM-19944	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1211936|imex:IM-19944-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001161753.1|refseq:NP_598545.2|dip:DIP-39476N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032835"(glomerulus development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:Q9EPK5|rcsb pdb:5GN0|reactome:R-MMU-2028269|reactome:R-MMU-2032785|reactome:R-MMU-2173796|ensembl:ENSMUSG00000027803(gene)|ensembl:ENSMUST00000029380(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003015"(heart process)|go:"GO:0003713"(transcription coactivator activity)	go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0060980"(cell migration involved in coronary vasculogenesis)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901846"(positive regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|rcsb pdb:2X6U|rcsb pdb:2X6V|rcsb pdb:4S0H|rcsb pdb:5BQD|reactome:R-HSA-2032785|reactome:R-HSA-5578768|refseq:NP_000183.2|refseq:NP_542448.1|refseq:NP_852259.1|ensembl:ENSG00000089225(gene)|ensembl:ENST00000310346(transcript)|ensembl:ENST00000405440(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)	-	-	-	comment:Removing fragments from residue 279 on decresed interaction strength.|figure legend:3B and 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/03/07	2014/10/16	rogid:K3vBlwaBtOtY1ERZlFti83hwZdc10090	rogid:gjw8Xw7q9o9hhhhjh+DgDZssmwU9606	intact-crc:B696665AA579F4F5|rigid:3bMFvKe5kD7VntAbruJg9NY2f58	false	myc tag:?-?	flag tag:?-?|sufficient binding region:1-279	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P46938	uniprotkb:Q9EPK5	intact:EBI-1211949|uniprotkb:Q91WL1|uniprotkb:Q52KJ5|ensembl:ENSMUSP00000069554	intact:EBI-1211920|uniprotkb:Q3UQ69|uniprotkb:Q3UQM0|uniprotkb:Q99KI4|ensembl:ENSMUSP00000029380	psi-mi:yap1_mouse(display_long)|uniprotkb:Yap1(gene name)|psi-mi:Yap1(display_short)|uniprotkb:Yap(gene name synonym)|uniprotkb:Yap65(gene name synonym)|uniprotkb:Protein yorkie homolog(gene name synonym)|uniprotkb:Yes-associated protein YAP65 homolog(gene name synonym)	psi-mi:wwtr1_mouse(display_long)|uniprotkb:Wwtr1(gene name)|psi-mi:Wwtr1(display_short)|uniprotkb:Taz(gene name synonym)|uniprotkb:Transcriptional coactivator with PDZ-binding motif(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Murakami et al. (2005)	pubmed:16332960|imex:IM-19944	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1211961|imex:IM-19944-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164618.1|refseq:NP_033560.1|dip:DIP-40015N|ensembl:ENSMUSG00000053110(gene)|ensembl:ENSMUST00000065353(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001674"(female germ cell nucleus)|go:"GO:0001824"(blastocyst development)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003015"(heart process)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032570"(response to progesterone)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048368"(lateral mesoderm development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060242"(contact inhibition)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140552"(TEAD-YAP complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:1904036"(negative regulation of epithelial cell apoptotic process)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:P46938|rcsb pdb:3JUA|rcsb pdb:6JK0|rcsb pdb:6JK1|reactome:R-MMU-1251985|reactome:R-MMU-2028269|reactome:R-MMU-2032785|reactome:R-MMU-8939236|reactome:R-MMU-8951671|go:"GO:0035329"(hippo signaling)	refseq:NP_001161753.1|refseq:NP_598545.2|dip:DIP-39476N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032835"(glomerulus development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:Q9EPK5|rcsb pdb:5GN0|reactome:R-MMU-2028269|reactome:R-MMU-2032785|reactome:R-MMU-2173796|ensembl:ENSMUSG00000027803(gene)|ensembl:ENSMUST00000029380(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003015"(heart process)|go:"GO:0003713"(transcription coactivator activity)	-	-	-	figure legend:3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/03/07	2014/10/16	rogid:3HcM3+sEb7cqRcBxi3jCxXRjT1810090	rogid:K3vBlwaBtOtY1ERZlFti83hwZdc10090	intact-crc:5DA5DA4A9C5F1C89|rigid:Gwja0EKbas82qA6A6L2azZgefwg	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9EPK5	uniprotkb:Q9EPK5	intact:EBI-1211920|uniprotkb:Q3UQ69|uniprotkb:Q3UQM0|uniprotkb:Q99KI4|ensembl:ENSMUSP00000029380	intact:EBI-1211920|uniprotkb:Q3UQ69|uniprotkb:Q3UQM0|uniprotkb:Q99KI4|ensembl:ENSMUSP00000029380	psi-mi:wwtr1_mouse(display_long)|uniprotkb:Wwtr1(gene name)|psi-mi:Wwtr1(display_short)|uniprotkb:Taz(gene name synonym)|uniprotkb:Transcriptional coactivator with PDZ-binding motif(gene name synonym)	psi-mi:wwtr1_mouse(display_long)|uniprotkb:Wwtr1(gene name)|psi-mi:Wwtr1(display_short)|uniprotkb:Taz(gene name synonym)|uniprotkb:Transcriptional coactivator with PDZ-binding motif(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Murakami et al. (2005)	pubmed:16332960|imex:IM-19944	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1211970|imex:IM-19944-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001161753.1|refseq:NP_598545.2|dip:DIP-39476N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032835"(glomerulus development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:Q9EPK5|rcsb pdb:5GN0|reactome:R-MMU-2028269|reactome:R-MMU-2032785|reactome:R-MMU-2173796|ensembl:ENSMUSG00000027803(gene)|ensembl:ENSMUST00000029380(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003015"(heart process)|go:"GO:0003713"(transcription coactivator activity)	refseq:NP_001161753.1|refseq:NP_598545.2|dip:DIP-39476N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032835"(glomerulus development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:Q9EPK5|rcsb pdb:5GN0|reactome:R-MMU-2028269|reactome:R-MMU-2032785|reactome:R-MMU-2173796|ensembl:ENSMUSG00000027803(gene)|ensembl:ENSMUST00000029380(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003015"(heart process)|go:"GO:0003713"(transcription coactivator activity)	-	-	-	figure legend:3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/03/07	2014/10/16	rogid:K3vBlwaBtOtY1ERZlFti83hwZdc10090	rogid:K3vBlwaBtOtY1ERZlFti83hwZdc10090	intact-crc:4D120EE0F55D1460|rigid:ZEAQgsr+lFEl4EZODbiJnb4Ypxw	false	myc tag:?-?	flag tag:?-?|necessary binding region:231-395	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P45481	uniprotkb:Q9EPK5	intact:EBI-296306|uniprotkb:E9QPH4	intact:EBI-1211920|uniprotkb:Q3UQ69|uniprotkb:Q3UQM0|uniprotkb:Q99KI4|ensembl:ENSMUSP00000029380	psi-mi:cbp_mouse(display_long)|uniprotkb:Crebbp(gene name)|psi-mi:Crebbp(display_short)|uniprotkb:Cbp(gene name synonym)|uniprotkb:Protein-lysine acetyltransferase CREBBP(gene name synonym)	psi-mi:wwtr1_mouse(display_long)|uniprotkb:Wwtr1(gene name)|psi-mi:Wwtr1(display_short)|uniprotkb:Taz(gene name synonym)|uniprotkb:Transcriptional coactivator with PDZ-binding motif(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Murakami et al. (2005)	pubmed:16332960|imex:IM-19944	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1211981|imex:IM-19944-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000940"(outer kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006473"(protein acetylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043426"(MRF binding)|rcsb pdb:1KBH|rcsb pdb:1KDX|rcsb pdb:1JJS|rcsb pdb:1L8C|rcsb pdb:1R8U|rcsb pdb:1SB0|rcsb pdb:1TOT|rcsb pdb:1U2N|rcsb pdb:2AGH|rcsb pdb:2C52|rcsb pdb:2KA4|rcsb pdb:2KA6|rcsb pdb:2KKJ|rcsb pdb:2L14|rcsb pdb:2LQH|rcsb pdb:2LQI|rcsb pdb:2LWW|rcsb pdb:4I9O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5U4K|rcsb pdb:5U7G|rcsb pdb:5W0I|rcsb pdb:6DMX|rcsb pdb:6DNQ|reactome:R-MMU-1234158|reactome:R-MMU-201722|reactome:R-MMU-2122947|reactome:R-MMU-3134973|reactome:R-MMU-3371568|reactome:R-MMU-350054|reactome:R-MMU-400206|reactome:R-MMU-5621575|reactome:R-MMU-8866907|reactome:R-MMU-8939246|reactome:R-MMU-8941856|reactome:R-MMU-9018519|reactome:R-MMU-918233|reactome:R-MMU-933541|reactome:R-MMU-9617629|reactome:R-MMU-9707564|go:"GO:0046332"(SMAD binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0048525"(negative regulation of viral process)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|rcsb pdb:1F81|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|mint:P45481|dip:DIP-5974N	refseq:NP_001161753.1|refseq:NP_598545.2|dip:DIP-39476N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032835"(glomerulus development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:Q9EPK5|rcsb pdb:5GN0|reactome:R-MMU-2028269|reactome:R-MMU-2032785|reactome:R-MMU-2173796|ensembl:ENSMUSG00000027803(gene)|ensembl:ENSMUST00000029380(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003015"(heart process)|go:"GO:0003713"(transcription coactivator activity)	-	-	-	figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/03/07	2014/10/16	rogid:sBMFm6ZE5MtCDEN3UiSiwTbvSqA10090	rogid:K3vBlwaBtOtY1ERZlFti83hwZdc10090	intact-crc:916E3C20442EB97E|rigid:ze2ZcOGcRQUpPh7gTOmovY4urgI	false	ha tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9EPK5	uniprotkb:Q92831	intact:EBI-1211920|uniprotkb:Q3UQ69|uniprotkb:Q3UQM0|uniprotkb:Q99KI4|ensembl:ENSMUSP00000029380	intact:EBI-477430|uniprotkb:Q6NSK1|ensembl:ENSP00000263754	psi-mi:wwtr1_mouse(display_long)|uniprotkb:Wwtr1(gene name)|psi-mi:Wwtr1(display_short)|uniprotkb:Taz(gene name synonym)|uniprotkb:Transcriptional coactivator with PDZ-binding motif(gene name synonym)	psi-mi:kat2b_human(display_long)|uniprotkb:P300/CBP-associated factor(gene name synonym)|uniprotkb:PCAF(gene name synonym)|uniprotkb:Lysine acetyltransferase 2B(gene name synonym)|uniprotkb:Histone acetyltransferase PCAF(gene name synonym)|uniprotkb:KAT2B(gene name)|psi-mi:KAT2B(display_short)|uniprotkb:Spermidine acetyltransferase KAT2B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Murakami et al. (2005)	pubmed:16332960|imex:IM-19944	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1212010|imex:IM-19944-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001161753.1|refseq:NP_598545.2|dip:DIP-39476N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032835"(glomerulus development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:Q9EPK5|rcsb pdb:5GN0|reactome:R-MMU-2028269|reactome:R-MMU-2032785|reactome:R-MMU-2173796|ensembl:ENSMUSG00000027803(gene)|ensembl:ENSMUST00000029380(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003015"(heart process)|go:"GO:0003713"(transcription coactivator activity)	ensembl:ENSG00000114166(gene)|ensembl:ENST00000263754(transcript)|go:"GO:0000125"|go:"GO:0000776"(kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006473"(protein acetylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|refseq:NP_003875.3|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060173"(limb development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:2000233"(negative regulation of rRNA processing)|interpro:IPR000182(GCN5-related N-acetyltransferase)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|go:"GO:0042826"(histone deacetylase binding)|interpro:IPR036427|interpro:IPR037800|mint:Q92831|rcsb pdb:1CM0|rcsb pdb:1JM4|rcsb pdb:1N72|rcsb pdb:1WUG|rcsb pdb:1WUM|rcsb pdb:1ZS5|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:3GG3|rcsb pdb:4NSQ|rcsb pdb:5FDZ|rcsb pdb:5FE0|rcsb pdb:5FE1|rcsb pdb:5FE2|rcsb pdb:5FE3|rcsb pdb:5FE4|rcsb pdb:5FE5|rcsb pdb:5FE6|rcsb pdb:5FE7|rcsb pdb:5FE8|rcsb pdb:5FE9|rcsb pdb:5LVQ|rcsb pdb:5LVR|rcsb pdb:5MKX|rcsb pdb:6J3O|reactome:R-HSA-1912408|reactome:R-HSA-2032785|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5578768|reactome:R-HSA-5689901|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9617629|dip:DIP-29778N	-	-	-	figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/03/07	2014/10/16	rogid:K3vBlwaBtOtY1ERZlFti83hwZdc10090	rogid:g0Gzr/F28rlhpv1qBl+kMEuwlZI9606	intact-crc:89B29426062510C4|rigid:Rrbbo/EToubkWSh4+jDzS7utuac	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-1212037	uniprotkb:Q99593	-	intact:EBI-297043|uniprotkb:O15301|uniprotkb:Q9Y4I2|ensembl:ENSP00000309913|ensembl:ENSP00000384152|uniprotkb:A6ND77|uniprotkb:Q96TB0	psi-mi:tbe_human-dna(display_short)|psi-mi:EBI-1212037(display_long)	psi-mi:tbx5_human(display_long)|uniprotkb:TBX5(gene name)|psi-mi:TBX5(display_short)	psi-mi:"MI:0096"(pull down)	Murakami et al. (2005)	pubmed:16332960|imex:IM-19944	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1212040|imex:IM-19944-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0060980"(cell migration involved in coronary vasculogenesis)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901846"(positive regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|rcsb pdb:2X6U|rcsb pdb:2X6V|rcsb pdb:4S0H|rcsb pdb:5BQD|reactome:R-HSA-2032785|reactome:R-HSA-5578768|refseq:NP_000183.2|refseq:NP_542448.1|refseq:NP_852259.1|ensembl:ENSG00000089225(gene)|ensembl:ENST00000310346(transcript)|ensembl:ENST00000405440(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)	-	-	-	figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/03/07	2014/10/16	crc64:219AED6C803981E8	rogid:gjw8Xw7q9o9hhhhjh+DgDZssmwU9606	intact-crc:E0F3ECF599761BEF	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-1212037	uniprotkb:Q9EPK5	-	intact:EBI-1211920|uniprotkb:Q3UQ69|uniprotkb:Q3UQM0|uniprotkb:Q99KI4|ensembl:ENSMUSP00000029380	psi-mi:tbe_human-dna(display_short)|psi-mi:EBI-1212037(display_long)	psi-mi:wwtr1_mouse(display_long)|uniprotkb:Wwtr1(gene name)|psi-mi:Wwtr1(display_short)|uniprotkb:Taz(gene name synonym)|uniprotkb:Transcriptional coactivator with PDZ-binding motif(gene name synonym)	psi-mi:"MI:0096"(pull down)	Murakami et al. (2005)	pubmed:16332960|imex:IM-19944	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1212040|imex:IM-19944-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001161753.1|refseq:NP_598545.2|dip:DIP-39476N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032835"(glomerulus development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:Q9EPK5|rcsb pdb:5GN0|reactome:R-MMU-2028269|reactome:R-MMU-2032785|reactome:R-MMU-2173796|ensembl:ENSMUSG00000027803(gene)|ensembl:ENSMUST00000029380(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003015"(heart process)|go:"GO:0003713"(transcription coactivator activity)	-	-	-	figure legend:3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/03/07	2014/10/16	crc64:219AED6C803981E8	rogid:K3vBlwaBtOtY1ERZlFti83hwZdc10090	intact-crc:E0F3ECF599761BEF	false	-	myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-1212037	uniprotkb:Q99593	-	intact:EBI-297043|uniprotkb:O15301|uniprotkb:Q9Y4I2|ensembl:ENSP00000309913|ensembl:ENSP00000384152|uniprotkb:A6ND77|uniprotkb:Q96TB0	psi-mi:tbe_human-dna(display_short)|psi-mi:EBI-1212037(display_long)	psi-mi:tbx5_human(display_long)|uniprotkb:TBX5(gene name)|psi-mi:TBX5(display_short)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Murakami et al. (2005)	pubmed:16332960|imex:IM-19944	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1212061|imex:IM-19944-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0060980"(cell migration involved in coronary vasculogenesis)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901846"(positive regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|rcsb pdb:2X6U|rcsb pdb:2X6V|rcsb pdb:4S0H|rcsb pdb:5BQD|reactome:R-HSA-2032785|reactome:R-HSA-5578768|refseq:NP_000183.2|refseq:NP_542448.1|refseq:NP_852259.1|ensembl:ENSG00000089225(gene)|ensembl:ENST00000310346(transcript)|ensembl:ENST00000405440(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)	-	-	-	figure legend:5B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/03/07	2014/10/16	crc64:219AED6C803981E8	rogid:gjw8Xw7q9o9hhhhjh+DgDZssmwU9606	intact-crc:A40BC3BD134754FF	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)