#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P32561	uniprotkb:P38255	intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C	intact:EBI-21537|uniprotkb:D6VQ96|ensemblfungi:YBR095C	psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym)	psi-mi:rxt2_yeast(display_long)|uniprotkb:YBR095C(locus name)|uniprotkb:YBR0822(orf name)|uniprotkb:RXT2(gene name)|psi-mi:RXT2(display_short)|uniprotkb:RAF60(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Colina et al. (2005)	pubmed:16275642|imex:IM-19438	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1370024|imex:IM-19438-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561	refseq:NP_009653.2|sgd:S000000299|mint:P38255|dip:DIP-6755N|ensemblfungi:YBR095C(gene)|ensemblfungi:YBR095C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016575"(histone deacetylation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:1990483"(Clr6 histone deacetylase complex I'')|go:"GO:2000219"(positive regulation of invasive growth in response to glucose limitation)|interpro:IPR013904(RXT2-like, N-terminal)|interpro:IPR039602	-	crc64:34FFD72A7E7425DB	-	figure legend:1|comment:"PHO23 (AcNo:P50947), SDS3 (AcNo: P40505) and SAP30 (AcNo: P40505) have also been found in the Rpd3 complex (shown on silver-stained gel)."|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/07/16	2014/10/16	rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292	rogid:vyk+t+m5t/bXnmpMYfeVXe4I1W0559292	intact-crc:366E46F9B9D1B6F6|rigid:0zjhUVboxfNhQJVZztuesSPkLXg	false	calmodulin binding peptide plus protein a tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P32561	uniprotkb:P22579	intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C	intact:EBI-17160|uniprotkb:Q08049|ensemblfungi:YOL004W|uniprotkb:D6W263	psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym)	psi-mi:sin3_yeast(display_long)|uniprotkb:YOL004W(locus name)|uniprotkb:GAM2(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:SDS16(gene name synonym)|uniprotkb:UME4(gene name synonym)|uniprotkb:SIN3(gene name)|psi-mi:SIN3(display_short)|uniprotkb:CPE1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Colina et al. (2005)	pubmed:16275642|imex:IM-19438	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1370024|imex:IM-19438-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561	ensemblfungi:YOL004W(gene)|ensemblfungi:YOL004W_mRNA(transcript)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0016575"(histone deacetylation)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070550"(rDNA condensation)|go:"GO:0070822"(Sin3-type complex)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR039774|rcsb pdb:6XDJ|rcsb pdb:6XAW|refseq:NP_014639.1|sgd:S000005364|dip:DIP-597N|mint:P22579	-	crc64:34FFD72A7E7425DB	crc64:0834726312B13878	figure legend:1|comment:"PHO23 (AcNo:P50947), SDS3 (AcNo: P40505) and SAP30 (AcNo: P40505) have also been found in the Rpd3 complex (shown on silver-stained gel)."|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/07/16	2014/10/16	rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292	rogid:6qsGcTahoTQo/AMso/5xKmpyVPk559292	intact-crc:366E46F9B9D1B6F6|rigid:0zjhUVboxfNhQJVZztuesSPkLXg	false	calmodulin binding peptide plus protein a tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P38255	uniprotkb:P32561	intact:EBI-21537|uniprotkb:D6VQ96|ensemblfungi:YBR095C	intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C	psi-mi:rxt2_yeast(display_long)|uniprotkb:YBR095C(locus name)|uniprotkb:YBR0822(orf name)|uniprotkb:RXT2(gene name)|psi-mi:RXT2(display_short)|uniprotkb:RAF60(gene name synonym)	psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Colina et al. (2005)	pubmed:16275642|imex:IM-19438	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1370051|imex:IM-19438-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009653.2|sgd:S000000299|mint:P38255|dip:DIP-6755N|ensemblfungi:YBR095C(gene)|ensemblfungi:YBR095C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016575"(histone deacetylation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:1990483"(Clr6 histone deacetylase complex I'')|go:"GO:2000219"(positive regulation of invasive growth in response to glucose limitation)|interpro:IPR013904(RXT2-like, N-terminal)|interpro:IPR039602	ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561	-	-	crc64:34FFD72A7E7425DB	figure legend:2A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/07/16	2014/10/16	rogid:vyk+t+m5t/bXnmpMYfeVXe4I1W0559292	rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292	intact-crc:EB7E5E4EB7F6AE50|rigid:JpF9nbTJzqkIuKHpgUmdCQVj1YI	false	ha tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P32561	uniprotkb:P22579	intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C	intact:EBI-17160|uniprotkb:Q08049|ensemblfungi:YOL004W|uniprotkb:D6W263	psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym)	psi-mi:sin3_yeast(display_long)|uniprotkb:YOL004W(locus name)|uniprotkb:GAM2(gene name synonym)|uniprotkb:RPD1(gene name synonym)|uniprotkb:SDI1(gene name synonym)|uniprotkb:SDS16(gene name synonym)|uniprotkb:UME4(gene name synonym)|uniprotkb:SIN3(gene name)|psi-mi:SIN3(display_short)|uniprotkb:CPE1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Colina et al. (2005)	pubmed:16275642|imex:IM-19438	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1370059|imex:IM-19438-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561	ensemblfungi:YOL004W(gene)|ensemblfungi:YOL004W_mRNA(transcript)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0016575"(histone deacetylation)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070550"(rDNA condensation)|go:"GO:0070822"(Sin3-type complex)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR039774|rcsb pdb:6XDJ|rcsb pdb:6XAW|refseq:NP_014639.1|sgd:S000005364|dip:DIP-597N|mint:P22579	-	crc64:34FFD72A7E7425DB	crc64:0834726312B13878	figure legend:2A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/07/16	2014/10/16	rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292	rogid:6qsGcTahoTQo/AMso/5xKmpyVPk559292	intact-crc:5CE678FF39300DE4|rigid:kxWwBYqWTpdifJvaTf9KR8qKJZ4	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P38255	uniprotkb:P32561	intact:EBI-21537|uniprotkb:D6VQ96|ensemblfungi:YBR095C	intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C	psi-mi:rxt2_yeast(display_long)|uniprotkb:YBR095C(locus name)|uniprotkb:YBR0822(orf name)|uniprotkb:RXT2(gene name)|psi-mi:RXT2(display_short)|uniprotkb:RAF60(gene name synonym)	psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Colina et al. (2005)	pubmed:16275642|imex:IM-19438	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1370075|imex:IM-19438-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009653.2|sgd:S000000299|mint:P38255|dip:DIP-6755N|ensemblfungi:YBR095C(gene)|ensemblfungi:YBR095C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016575"(histone deacetylation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:1990483"(Clr6 histone deacetylase complex I'')|go:"GO:2000219"(positive regulation of invasive growth in response to glucose limitation)|interpro:IPR013904(RXT2-like, N-terminal)|interpro:IPR039602	ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561	-	-	crc64:34FFD72A7E7425DB	figure legend:2B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/07/16	2014/10/16	rogid:vyk+t+m5t/bXnmpMYfeVXe4I1W0559292	rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292	intact-crc:7762339772EDBBB2|rigid:JpF9nbTJzqkIuKHpgUmdCQVj1YI	false	myc tag:?-?	calmodulin binding peptide plus protein a tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)