#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P32598 uniprotkb:P27637 intact:EBI-13715|ensemblfungi:YER133W|uniprotkb:D3DM39 intact:EBI-20747|uniprotkb:D6VPM3|ensemblfungi:YAR014C psi-mi:pp12_yeast(display_long)|uniprotkb:GLC7(gene name)|psi-mi:GLC7(display_short)|uniprotkb:CID1(gene name synonym)|uniprotkb:DIS2(gene name synonym)|uniprotkb:YER133W(locus name) psi-mi:bud14_yeast(display_long)|uniprotkb:FUN2(orf name)|uniprotkb:YAR014C(locus name)|uniprotkb:BUD14(gene name)|psi-mi:BUD14(display_short) psi-mi:"MI:0018"(two hybrid) Knaus et al. (2005) pubmed:16107882 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1369026 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER133W(gene)|ensemblfungi:YER133W_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000776"(kinetochore)|go:"GO:0001400"(mating projection base)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006397"(mRNA processing)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007116"(regulation of cell budding)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009408"(response to heat)|go:"GO:0005816"(spindle pole body)|go:"GO:0016576"(histone dephosphorylation)|go:"GO:0030437"(ascospore formation)|go:"GO:0031297"(replication fork processing)|go:"GO:0032153"(cell division site)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070873"(regulation of glycogen metabolic process)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901901"(regulation of protein localization to cell division site involved in cytokinesis)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|sgd:S000000935|refseq:NP_011059.3|mint:P32598|dip:DIP-1336N refseq:NP_009408.3|sgd:S000000069|mint:P27637|ensemblfungi:YAR014C(gene)|ensemblfungi:YAR014C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0051286"(cell tip)|go:"GO:0051301"(cell division)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:1990615"(Kelch-containing formin regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|dip:DIP-1756N - crc64:71B20E3A4ED93235 crc64:F123511A4C592EB4 figure legend:Table I taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/12 2014/10/16 rogid:wXXOB38if1fxEN0yLxeYTCXsuyU559292 rogid:U/J6oV49Yml8AtGtqzZVi5WjZqc559292 intact-crc:AD622DD0D513A02C|rigid:E4sOpbqu8OFqjuPRHrEBfV7drx4 false - sufficient binding region:340-707|mutation decreasing interaction:377-377|mutation decreasing interaction:379-379 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27637 uniprotkb:P39960 intact:EBI-20747|uniprotkb:D6VPM3|ensemblfungi:YAR014C intact:EBI-3517|uniprotkb:D3DM62|ensemblfungi:YER155C psi-mi:bud14_yeast(display_long)|uniprotkb:FUN2(orf name)|uniprotkb:YAR014C(locus name)|uniprotkb:BUD14(gene name)|psi-mi:BUD14(display_short) psi-mi:bem2_yeast(display_long)|uniprotkb:Bud emergence protein 2(gene name synonym)|uniprotkb:YER155C(locus name)|uniprotkb:BEM2(gene name)|psi-mi:BEM2(display_short)|uniprotkb:IPL2(gene name synonym)|uniprotkb:SUP9(gene name synonym) psi-mi:"MI:0018"(two hybrid) Knaus et al. (2005) pubmed:16107882 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1369066 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009408.3|sgd:S000000069|mint:P27637|ensemblfungi:YAR014C(gene)|ensemblfungi:YAR014C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0051286"(cell tip)|go:"GO:0051301"(cell division)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:1990615"(Kelch-containing formin regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|dip:DIP-1756N sgd:S000000957|refseq:NP_011082.3|dip:DIP-6580N|mint:P39960|ensemblfungi:YER155C(gene)|ensemblfungi:YER155C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003729"(mRNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005938"(cell cortex)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0044879"(mitotic morphogenesis checkpoint signaling)|interpro:IPR000198(RhoGAP)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023578|interpro:IPR036964|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034 - crc64:F123511A4C592EB4 crc64:DB7F4CD417E898F0 figure legend:Table I taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/12 2014/10/16 rogid:U/J6oV49Yml8AtGtqzZVi5WjZqc559292 rogid:ddSX4LBPZO2nurHU7fUNTk3ozxI559292 intact-crc:A41EE54162FC7A08|rigid:iRPfziX+DfxJbf9JIZEPswkY5vA false mutation decreasing interaction:379-379 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32598 uniprotkb:P27637 intact:EBI-13715|ensemblfungi:YER133W|uniprotkb:D3DM39 intact:EBI-20747|uniprotkb:D6VPM3|ensemblfungi:YAR014C psi-mi:pp12_yeast(display_long)|uniprotkb:GLC7(gene name)|psi-mi:GLC7(display_short)|uniprotkb:CID1(gene name synonym)|uniprotkb:DIS2(gene name synonym)|uniprotkb:YER133W(locus name) psi-mi:bud14_yeast(display_long)|uniprotkb:FUN2(orf name)|uniprotkb:YAR014C(locus name)|uniprotkb:BUD14(gene name)|psi-mi:BUD14(display_short) psi-mi:"MI:0018"(two hybrid) Knaus et al. (2005) pubmed:16107882 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1369092 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER133W(gene)|ensemblfungi:YER133W_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000776"(kinetochore)|go:"GO:0001400"(mating projection base)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006397"(mRNA processing)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007116"(regulation of cell budding)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009408"(response to heat)|go:"GO:0005816"(spindle pole body)|go:"GO:0016576"(histone dephosphorylation)|go:"GO:0030437"(ascospore formation)|go:"GO:0031297"(replication fork processing)|go:"GO:0032153"(cell division site)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070873"(regulation of glycogen metabolic process)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901901"(regulation of protein localization to cell division site involved in cytokinesis)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|sgd:S000000935|refseq:NP_011059.3|mint:P32598|dip:DIP-1336N refseq:NP_009408.3|sgd:S000000069|mint:P27637|ensemblfungi:YAR014C(gene)|ensemblfungi:YAR014C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0051286"(cell tip)|go:"GO:0051301"(cell division)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:1990615"(Kelch-containing formin regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|dip:DIP-1756N - crc64:71B20E3A4ED93235 crc64:F123511A4C592EB4 figure legend:Table I taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/12 2014/10/16 rogid:wXXOB38if1fxEN0yLxeYTCXsuyU559292 rogid:U/J6oV49Yml8AtGtqzZVi5WjZqc559292 intact-crc:AD05A79C3E0DEBFE|rigid:E4sOpbqu8OFqjuPRHrEBfV7drx4 false mutation decreasing interaction:190-190,186-187,298-298 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32598 uniprotkb:P27637 intact:EBI-13715|ensemblfungi:YER133W|uniprotkb:D3DM39 intact:EBI-20747|uniprotkb:D6VPM3|ensemblfungi:YAR014C psi-mi:pp12_yeast(display_long)|uniprotkb:GLC7(gene name)|psi-mi:GLC7(display_short)|uniprotkb:CID1(gene name synonym)|uniprotkb:DIS2(gene name synonym)|uniprotkb:YER133W(locus name) psi-mi:bud14_yeast(display_long)|uniprotkb:FUN2(orf name)|uniprotkb:YAR014C(locus name)|uniprotkb:BUD14(gene name)|psi-mi:BUD14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Knaus et al. (2005) pubmed:16107882 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1369252 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER133W(gene)|ensemblfungi:YER133W_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000776"(kinetochore)|go:"GO:0001400"(mating projection base)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006397"(mRNA processing)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007116"(regulation of cell budding)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009408"(response to heat)|go:"GO:0005816"(spindle pole body)|go:"GO:0016576"(histone dephosphorylation)|go:"GO:0030437"(ascospore formation)|go:"GO:0031297"(replication fork processing)|go:"GO:0032153"(cell division site)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070873"(regulation of glycogen metabolic process)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901901"(regulation of protein localization to cell division site involved in cytokinesis)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|sgd:S000000935|refseq:NP_011059.3|mint:P32598|dip:DIP-1336N refseq:NP_009408.3|sgd:S000000069|mint:P27637|ensemblfungi:YAR014C(gene)|ensemblfungi:YAR014C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0051286"(cell tip)|go:"GO:0051301"(cell division)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:1990615"(Kelch-containing formin regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|dip:DIP-1756N - crc64:71B20E3A4ED93235 crc64:F123511A4C592EB4 figure legend:Figure 4B taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/12 2014/10/16 rogid:wXXOB38if1fxEN0yLxeYTCXsuyU559292 rogid:U/J6oV49Yml8AtGtqzZVi5WjZqc559292 intact-crc:DCD7D5FFB96B139F|rigid:E4sOpbqu8OFqjuPRHrEBfV7drx4 false ha tag:?-? glutathione s tranferase tag:?-?|mutation decreasing interaction:377-377|mutation decreasing interaction:379-379 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)