#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q99MH6	uniprotkb:Q06190-2	intact:EBI-1538321|uniprotkb:Q3TLD6|uniprotkb:Q8K200|uniprotkb:Q91Y46|ensembl:ENSMUSP00000034086	intact:EBI-949210|ensembl:ENSP00000334748	psi-mi:nkd1_mouse(display_long)|uniprotkb:Nkd1(gene name)|psi-mi:Nkd1(display_short)	psi-mi:q06190-2(display_long)|uniprotkb:72 kDa(isoform synonym)|uniprotkb:PPP2R3A(gene name)|psi-mi:PPP2R3A(display_short)|uniprotkb:PPP2R3(gene name synonym)|uniprotkb:PP2A subunit B isoform PR72/PR130(gene name synonym)|uniprotkb:PP2A subunit B isoform R3 isoform(gene name synonym)|uniprotkb:PP2A subunit B isoforms B''-PR72/PR130(gene name synonym)|uniprotkb:PP2A subunit B isoforms B72/B130(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Creyghton et al. (2005)	pubmed:15687260|imex:IM-19608	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1538318|imex:IM-19608-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_081556.3|ensembl:ENSMUSG00000031661(gene)|ensembl:ENSMUST00000034086(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1901231"(positive regulation of non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:1901233"(negative regulation of convergent extension involved in axis elongation)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040140	ensembl:ENSG00000073711(gene)|ensembl:ENST00000334546(transcript)|intact:EBI-949190(2aca_human)	-	-	-	figure legend:Fig 1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/26	2014/10/16	rogid:liCzM7mnKqPRck5uBbY8CM5iyXQ10090	rogid:RRymMlFjUNidnB9scFZWUNc7QeE9606	intact-crc:17C7D1A0130A3024|rigid:75R5hMiqEemWar/4ZnAshH3IjFw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q969G9	uniprotkb:Q06190-2	intact:EBI-1538217|uniprotkb:Q8WZ08|uniprotkb:B2RC39|ensembl:ENSP00000268459	intact:EBI-949210|ensembl:ENSP00000334748	psi-mi:nkd1_human(display_long)|uniprotkb:NKD1(gene name)|psi-mi:NKD1(display_short)|uniprotkb:NKD(gene name synonym)|uniprotkb:PP7246(orf name)	psi-mi:q06190-2(display_long)|uniprotkb:72 kDa(isoform synonym)|uniprotkb:PPP2R3A(gene name)|psi-mi:PPP2R3A(display_short)|uniprotkb:PPP2R3(gene name synonym)|uniprotkb:PP2A subunit B isoform PR72/PR130(gene name synonym)|uniprotkb:PP2A subunit B isoform R3 isoform(gene name synonym)|uniprotkb:PP2A subunit B isoforms B''-PR72/PR130(gene name synonym)|uniprotkb:PP2A subunit B isoforms B72/B130(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Creyghton et al. (2005)	pubmed:15687260|imex:IM-19608	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1538347|imex:IM-19608-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149110.1|dip:DIP-38248N|ensembl:ENSG00000140807(gene)|ensembl:ENST00000268459(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007525"(somatic muscle development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090249"(regulation of cell migration involved in somitogenic axis elongation)|go:"GO:1901231"(positive regulation of non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:1901233"(negative regulation of convergent extension involved in axis elongation)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040140	ensembl:ENSG00000073711(gene)|ensembl:ENST00000334546(transcript)|intact:EBI-949190(2aca_human)	-	-	-	figure legend:Fig 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/09/26	2014/10/16	rogid:vqhYF/I4xygYiMRkKziruVar/e09606	rogid:RRymMlFjUNidnB9scFZWUNc7QeE9606	intact-crc:117759EF9404CD9A|rigid:nH/CFEtYWxt0sotUnOwUQnl9uac	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q969G9	uniprotkb:P51141	intact:EBI-1538217|uniprotkb:Q8WZ08|uniprotkb:B2RC39|ensembl:ENSP00000268459	intact:EBI-1538407|uniprotkb:Q60868|uniprotkb:Q3U2D3|ensembl:ENSMUSP00000030948|ensembl:ENSMUSP00000133137	psi-mi:nkd1_human(display_long)|uniprotkb:NKD1(gene name)|psi-mi:NKD1(display_short)|uniprotkb:NKD(gene name synonym)|uniprotkb:PP7246(orf name)	psi-mi:dvl1_mouse(display_long)|uniprotkb:Dvl1(gene name)|psi-mi:Dvl1(display_short)|uniprotkb:Dvl(gene name synonym)|uniprotkb:DSH homolog 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Creyghton et al. (2005)	pubmed:15687260|imex:IM-19608	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1538355|imex:IM-19608-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149110.1|dip:DIP-38248N|ensembl:ENSG00000140807(gene)|ensembl:ENST00000268459(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007525"(somatic muscle development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090249"(regulation of cell migration involved in somitogenic axis elongation)|go:"GO:1901231"(positive regulation of non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:1901233"(negative regulation of convergent extension involved in axis elongation)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040140	refseq:NP_034221.3|refseq:NP_001289271.1|dip:DIP-38263N|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035176"(social behavior)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048668"(collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099173"(postsynapse organization)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008340(Dishevelled-1 protein)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|rcsb pdb:1FSH|rcsb pdb:1MC7|rcsb pdb:2KAW|rcsb pdb:2MX6|rcsb pdb:3PZ8|reactome:R-MMU-201688|reactome:R-MMU-4086400|reactome:R-MMU-4641258|reactome:R-MMU-4641262|reactome:R-MMU-5663220|ensembl:ENSMUSG00000029071(gene)|ensembl:ENSMUST00000030948(transcript)|ensembl:ENSMUST00000168552(transcript)|go:"GO:0001505"(regulation of neurotransmitter levels)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)	-	-	-	figure legend:Fig 1B, 1C, 3D|inhibition:Interaction of NKD1 with DVL1 is inhibited by isoform PR72 of PPP2R3A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/09/26	2014/10/16	rogid:vqhYF/I4xygYiMRkKziruVar/e09606	rogid:m61iD63WqE333GDlyLU6Mlnq50o10090	intact-crc:CDCF0CBAB1749322|rigid:CiSR9Zq1nGaGSBvP6OhHhJOEIu0	false	flag tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q969G9	uniprotkb:P30153	intact:EBI-1538217|uniprotkb:Q8WZ08|uniprotkb:B2RC39|ensembl:ENSP00000268459	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	psi-mi:nkd1_human(display_long)|uniprotkb:NKD1(gene name)|psi-mi:NKD1(display_short)|uniprotkb:NKD(gene name synonym)|uniprotkb:PP7246(orf name)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Creyghton et al. (2005)	pubmed:15687260|imex:IM-19608	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1538355|imex:IM-19608-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149110.1|dip:DIP-38248N|ensembl:ENSG00000140807(gene)|ensembl:ENST00000268459(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007525"(somatic muscle development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090249"(regulation of cell migration involved in somitogenic axis elongation)|go:"GO:1901231"(positive regulation of non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:1901233"(negative regulation of convergent extension involved in axis elongation)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040140	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	-	-	-	figure legend:Fig 1B, 1C, 3D|inhibition:Interaction of NKD1 with DVL1 is inhibited by isoform PR72 of PPP2R3A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/09/26	2014/10/16	rogid:vqhYF/I4xygYiMRkKziruVar/e09606	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	intact-crc:CDCF0CBAB1749322|rigid:CiSR9Zq1nGaGSBvP6OhHhJOEIu0	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q969G9	uniprotkb:Q06190-2	intact:EBI-1538217|uniprotkb:Q8WZ08|uniprotkb:B2RC39|ensembl:ENSP00000268459	intact:EBI-949210|ensembl:ENSP00000334748	psi-mi:nkd1_human(display_long)|uniprotkb:NKD1(gene name)|psi-mi:NKD1(display_short)|uniprotkb:NKD(gene name synonym)|uniprotkb:PP7246(orf name)	psi-mi:q06190-2(display_long)|uniprotkb:72 kDa(isoform synonym)|uniprotkb:PPP2R3A(gene name)|psi-mi:PPP2R3A(display_short)|uniprotkb:PPP2R3(gene name synonym)|uniprotkb:PP2A subunit B isoform PR72/PR130(gene name synonym)|uniprotkb:PP2A subunit B isoform R3 isoform(gene name synonym)|uniprotkb:PP2A subunit B isoforms B''-PR72/PR130(gene name synonym)|uniprotkb:PP2A subunit B isoforms B72/B130(gene name synonym)|uniprotkb:Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Creyghton et al. (2005)	pubmed:15687260|imex:IM-19608	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1538355|imex:IM-19608-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149110.1|dip:DIP-38248N|ensembl:ENSG00000140807(gene)|ensembl:ENST00000268459(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007525"(somatic muscle development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090249"(regulation of cell migration involved in somitogenic axis elongation)|go:"GO:1901231"(positive regulation of non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:1901233"(negative regulation of convergent extension involved in axis elongation)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040140	ensembl:ENSG00000073711(gene)|ensembl:ENST00000334546(transcript)|intact:EBI-949190(2aca_human)	-	-	-	figure legend:Fig 1B, 1C, 3D|inhibition:Interaction of NKD1 with DVL1 is inhibited by isoform PR72 of PPP2R3A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/09/26	2014/10/16	rogid:vqhYF/I4xygYiMRkKziruVar/e09606	rogid:RRymMlFjUNidnB9scFZWUNc7QeE9606	intact-crc:CDCF0CBAB1749322|rigid:CiSR9Zq1nGaGSBvP6OhHhJOEIu0	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q969G9	uniprotkb:P67775	intact:EBI-1538217|uniprotkb:Q8WZ08|uniprotkb:B2RC39|ensembl:ENSP00000268459	intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197	psi-mi:nkd1_human(display_long)|uniprotkb:NKD1(gene name)|psi-mi:NKD1(display_short)|uniprotkb:NKD(gene name synonym)|uniprotkb:PP7246(orf name)	psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Creyghton et al. (2005)	pubmed:15687260|imex:IM-19608	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1538355|imex:IM-19608-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149110.1|dip:DIP-38248N|ensembl:ENSG00000140807(gene)|ensembl:ENST00000268459(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007525"(somatic muscle development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090249"(regulation of cell migration involved in somitogenic axis elongation)|go:"GO:1901231"(positive regulation of non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:1901233"(negative regulation of convergent extension involved in axis elongation)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR040140	ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N	-	-	-	figure legend:Fig 1B, 1C, 3D|inhibition:Interaction of NKD1 with DVL1 is inhibited by isoform PR72 of PPP2R3A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/09/26	2014/10/16	rogid:vqhYF/I4xygYiMRkKziruVar/e09606	rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606	intact-crc:CDCF0CBAB1749322|rigid:CiSR9Zq1nGaGSBvP6OhHhJOEIu0	false	flag tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)