#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P35187	uniprotkb:Q12083	intact:EBI-17059|uniprotkb:D6W014|ensemblfungi:YMR190C	intact:EBI-31634|uniprotkb:D6W3K4|ensemblfungi:YPL164C	psi-mi:sgs1_yeast(display_long)|uniprotkb:SGS1(gene name)|psi-mi:SGS1(display_short)|uniprotkb:TPS1(gene name synonym)|uniprotkb:YMR190C(locus name)|uniprotkb:YM9646.02C(orf name)|uniprotkb:Helicase TPS1(gene name synonym)	psi-mi:mlh3_yeast(display_long)|uniprotkb:MLH3(gene name)|psi-mi:MLH3(display_short)|uniprotkb:MutL protein homolog 3(gene name synonym)|uniprotkb:P2550(orf name)|uniprotkb:YPL164C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wang et al. (2002)	pubmed:12200140|imex:IM-19384	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1565839|imex:IM-19384-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010520"(regulation of reciprocal meiotic recombination)|go:"GO:0010947"(negative regulation of meiotic joint molecule formation)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051276"(chromosome organization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005634"(nucleus)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR022758|interpro:IPR027417|interpro:IPR032284|interpro:IPR036388|rcsb pdb:1D8B|interpro:IPR001650(DNA/RNA helicase, C-terminal)|refseq:NP_013915.1|sgd:S000004802|ensemblfungi:YMR190C(gene)|ensemblfungi:YMR190C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|dip:DIP-2911N|mint:P35187	refseq:NP_015161.1|sgd:S000006085|dip:DIP-2414N|ensemblfungi:YPL164C(gene)|ensemblfungi:YPL164C_mRNA(transcript)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0097587"(MutLgamma complex)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR028830|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|rcsb pdb:6RMN|rcsb pdb:6SHX|rcsb pdb:6SNS|rcsb pdb:6SNV	-	crc64:0DC320B41756A3C3	crc64:970FD7F57EB6E3B1	figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/07	2014/10/16	rogid:kSX/9U/Qjnhm6doWBmFCKOC8dJo559292	rogid:g47/5yM9oWZ13CIZOZ7QT6A+LW0559292	intact-crc:1C08A65C33978F2D|rigid:ucuqAz5MQ5IsVBpNluHLGSL+qBg	false	ha tag:c-c	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P13099	uniprotkb:P35187	intact:EBI-19365|uniprotkb:D6VYN4|ensemblfungi:YLR234W	intact:EBI-17059|uniprotkb:D6W014|ensemblfungi:YMR190C	psi-mi:top3_yeast(display_long)|uniprotkb:TOP3(gene name)|psi-mi:TOP3(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:YLR234W(locus name)|uniprotkb:L8083.3(orf name)|uniprotkb:DNA topoisomerase III(gene name synonym)	psi-mi:sgs1_yeast(display_long)|uniprotkb:SGS1(gene name)|psi-mi:SGS1(display_short)|uniprotkb:TPS1(gene name synonym)|uniprotkb:YMR190C(locus name)|uniprotkb:YM9646.02C(orf name)|uniprotkb:Helicase TPS1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wang et al. (2002)	pubmed:12200140|imex:IM-19384	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1565847|imex:IM-19384-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013335.1|sgd:S000004224|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|go:"GO:0003916"(DNA topoisomerase activity)|ensemblfungi:YLR234W(gene)|ensemblfungi:YLR234W_mRNA(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|dip:DIP-2912N|mint:P13099	go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0010520"(regulation of reciprocal meiotic recombination)|go:"GO:0010947"(negative regulation of meiotic joint molecule formation)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051276"(chromosome organization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005634"(nucleus)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010997(HRDC-like)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR018982|interpro:IPR022758|interpro:IPR027417|interpro:IPR032284|interpro:IPR036388|rcsb pdb:1D8B|interpro:IPR001650(DNA/RNA helicase, C-terminal)|refseq:NP_013915.1|sgd:S000004802|ensemblfungi:YMR190C(gene)|ensemblfungi:YMR190C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000706"(meiotic DNA double-strand break processing)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|dip:DIP-2911N|mint:P35187	-	crc64:51DF78936A88B4F4	crc64:0DC320B41756A3C3	figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/07	2014/10/16	rogid:7guk14sg6ZTut5+2ip8U/NkS9M0559292	rogid:kSX/9U/Qjnhm6doWBmFCKOC8dJo559292	intact-crc:FC2F5212198CDD28|rigid:mfOklneip12bobp9ceQkMEPq+aw	false	ha tag:c-c	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)