#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P01948 ddbj/embl/genbank:K02718 intact:EBI-1396075 intact:EBI-1397994 psi-mi:hba_rabit(display_long)|uniprotkb:Hemoglobin alpha-1/2 chain(gene name synonym)|uniprotkb:Alpha-1/2-globin(gene name synonym) psi-mi:20-mer e7(display_short)|psi-mi:K02718(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Kanduc et al. (2002) pubmed:12072504 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1396029 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0324"(messenger rna) refseq:NP_001075858.1|interpro:IPR009050(Globin-like)|interpro:IPR000971(Globin, subset)|interpro:IPR002338(Haemoglobin, alpha)|interpro:IPR002339(Haemoglobin, pi)|rcsb pdb:2RAO|interpro:IPR012292(Globin)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding) pubmed:12072504(primary-reference) - - comment:A 20-mer oligonucleotide complementary to the 3' end of HPV16 E7 mRNA figure legend:Figure 2, 3, 4|comment:A 32 kDa protein component within rabbit reticulocytes was shown to bind to hpv16 e7. The binding of E7 mRNA to a p32 component from rabbit reticulocyte lysate controls HPV16 E7 expression by preventing both degradation and translation of the viral transcript.|inhibition:"The 32 kDa protein component within rabbit reticulocytes was shown to inhibit hpv16 e7 mRNA degradation and translation. The effect of p32 on HPV16 E7 mRNA degradation was analyzed with the p32-depleted reticulocyte lysate preparation. This showed that E7 mRNA stability was markedly reduced when assayed in the p32-depleted reticulocyte lysate. Also p32 addition protected E7 mRNA (but not c-myc or eIF-4E mRNAs) from RNase A digestion. There was also a striking translational signal obtained by carrying out translation in the presence of anti-p32 Abs" taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/13 2014/10/16 rogid:sQnpAO7XQuoIH4w7QOyiRCZ9wJQ9986 crc64:6F22800B3F598BB1 intact-crc:0BA7CB4E0C5931FB false - - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) ddbj/embl/genbank:K02718 intact:EBI-1396712 intact:EBI-1397994 - psi-mi:20-mer e7(display_short)|psi-mi:K02718(display_long) psi-mi:seqika(display_short)|psi-mi:EBI-1396712(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Kanduc et al. (2002) pubmed:12072504 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:-1(in vitro)|taxid:-1(In vitro) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1396649 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0324"(messenger rna) psi-mi:"MI:0327"(peptide) pubmed:12072504(primary-reference) pubmed:12072504(primary-reference) - comment:A 20-mer oligonucleotide complementary to the 3' end of HPV16 E7 mRNA no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Small peptide present in human KRT7 and rabbit heamaglobin subunit alpha 1/2. figure legend:Figure 6A-D, 7C|comment:"Rabbit {alpha}1-globin52-57/human CK791-96 SEQIKA binds to, prevents decay of, and blocks translation of HPV16 E7 mRNA. Mutation of K (lys) at position 5 to L (leu) prevented binding suggesting that this residue is essential for peptide binding to HPV16 E7 mRNA." taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/13 2014/10/16 crc64:6F22800B3F598BB1 rogid:yyv36tbyE6N4UGHx8MszoSb4ifU-1 intact-crc:7AD891608E87FF48 false - biotin tag:?-?|binding-associated region:5-5 - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) ddbj/embl/genbank:K02718 uniprotkb:P01948 intact:EBI-1397994 intact:EBI-1396075 psi-mi:20-mer e7(display_short)|psi-mi:K02718(display_long) psi-mi:hba_rabit(display_long)|uniprotkb:Hemoglobin alpha-1/2 chain(gene name synonym)|uniprotkb:Alpha-1/2-globin(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Kanduc et al. (2002) pubmed:12072504 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1397804 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0324"(messenger rna) psi-mi:"MI:0326"(protein) pubmed:12072504(primary-reference) refseq:NP_001075858.1|interpro:IPR009050(Globin-like)|interpro:IPR000971(Globin, subset)|interpro:IPR002338(Haemoglobin, alpha)|interpro:IPR002339(Haemoglobin, pi)|rcsb pdb:2RAO|interpro:IPR012292(Globin)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding) - comment:A 20-mer oligonucleotide complementary to the 3' end of HPV16 E7 mRNA - figure legend:Table 2, Figure 7A, 7B|comment:Rabbit {alpha}1-globin 53-58 SEQIKA motif showed binding to radiolabeled HPV16 E7 mRNA by gel retardation experiments and this binding was suppressed by anti-p32Pabs. taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/13 2014/10/16 crc64:6F22800B3F598BB1 rogid:sQnpAO7XQuoIH4w7QOyiRCZ9wJQ9986 intact-crc:EE1D0D68F3F4EDE4 false - sufficient binding region:53-58 - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P69905 ddbj/embl/genbank:K02718 intact:EBI-714680|uniprotkb:P01922|ensembl:ENSP00000251595|ensembl:ENSP00000322421|uniprotkb:Q3MIF5|uniprotkb:Q96KF1|uniprotkb:Q9NYR7|uniprotkb:Q1HDT5|uniprotkb:Q53F97|uniprotkb:Q9UCM0 intact:EBI-1397994 psi-mi:hba_human(display_long)|uniprotkb:Hemoglobin alpha chain(gene name synonym)|uniprotkb:Alpha-globin(gene name synonym)|uniprotkb:HBA1(gene name)|psi-mi:HBA1(display_short)|uniprotkb:HBA2(gene name)|psi-mi:HBA2(display_short) psi-mi:20-mer e7(display_short)|psi-mi:K02718(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Kanduc et al. (2002) pubmed:12072504 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1397821 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0324"(messenger rna) ensembl:ENSG00000188536(gene)|ensembl:ENSG00000206172(gene)|ensembl:ENST00000251595(transcript)|ensembl:ENST00000320868(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0015671"(oxygen transport)|go:"GO:0016020"(membrane)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0072562"(blood microparticle)|go:"GO:0098869"(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002338(Haemoglobin, alpha)|interpro:IPR002339(Haemoglobin, pi)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|mint:P69905|rcsb pdb:1A00|rcsb pdb:1A01|rcsb pdb:1A0U|rcsb pdb:1A0Z|rcsb pdb:1A3N|rcsb pdb:1A3O|rcsb pdb:1A9W|rcsb pdb:1ABW|rcsb pdb:1ABY|rcsb pdb:1AJ9|rcsb pdb:1B86|rcsb pdb:1BAB|rcsb pdb:1BBB|rcsb pdb:1BIJ|rcsb pdb:1BUW|rcsb pdb:1BZ0|rcsb pdb:1BZ1|rcsb pdb:1BZZ|rcsb pdb:1C7B|rcsb pdb:1C7C|rcsb pdb:1C7D|rcsb pdb:1CLS|rcsb pdb:1CMY|rcsb pdb:1COH|rcsb pdb:1DKE|rcsb pdb:1DXT|rcsb pdb:1DXU|rcsb pdb:1DXV|rcsb pdb:1FDH|rcsb pdb:1FN3|rcsb pdb:1G9V|rcsb pdb:1YVQ|rcsb pdb:1YVT|rcsb pdb:1YZI|rcsb pdb:1Z8U|rcsb pdb:2D5Z|rcsb pdb:2D60|rcsb pdb:2DN1|rcsb pdb:2DN2|rcsb pdb:2DN3|rcsb pdb:2DXM|rcsb pdb:2H35|rcsb pdb:2HBC|rcsb pdb:2HBD|rcsb pdb:2HBE|rcsb pdb:2HBF|rcsb pdb:2HBS|rcsb pdb:2HCO|rcsb pdb:2HHB|rcsb pdb:2HHD|rcsb pdb:2HHE|rcsb pdb:2M6Z|rcsb pdb:2W6V|rcsb pdb:2W72|rcsb pdb:2YRS|rcsb pdb:3B75|rcsb pdb:3D17|rcsb pdb:3D7O|rcsb pdb:3DUT|rcsb pdb:3HHB|rcsb pdb:3HXN|rcsb pdb:3IA3|rcsb pdb:3IC0|rcsb pdb:3IC2|rcsb pdb:3KMF|rcsb pdb:3NL7|rcsb pdb:3NMM|rcsb pdb:3ODQ|rcsb pdb:3ONZ|rcsb pdb:3OO4|rcsb pdb:3OO5|rcsb pdb:3OVU|rcsb pdb:3P5Q|rcsb pdb:3QJB|rcsb pdb:3QJC|rcsb pdb:3QJD|rcsb pdb:3QJE|rcsb pdb:3R5I|rcsb pdb:3S48|rcsb pdb:3S65|rcsb pdb:3S66|rcsb pdb:3SZK|rcsb pdb:3WCP|rcsb pdb:3WHM|rcsb pdb:4FC3|rcsb pdb:4HHB|rcsb pdb:4IJ2|rcsb pdb:4L7Y|rcsb pdb:4M4A|rcsb pdb:4M4B|rcsb pdb:4MQC|rcsb pdb:4MQG|rcsb pdb:4MQH|rcsb pdb:4MQI|rcsb pdb:4MQJ|rcsb pdb:4MQK|rcsb pdb:4X0L|rcsb pdb:4XS0|rcsb pdb:5E29|rcsb pdb:5E6E|rcsb pdb:5E83|rcsb pdb:5EE4|rcsb pdb:5HU6|rcsb pdb:5HY8|rcsb pdb:5JDO|rcsb pdb:5KDQ|rcsb pdb:5KSI|rcsb pdb:5KSJ|rcsb pdb:5NI1|rcsb pdb:5SW7|rcsb pdb:5U3I|rcsb pdb:5UCU|rcsb pdb:5UFJ|rcsb pdb:5URC|rcsb pdb:5VMM|rcsb pdb:5WOG|rcsb pdb:5WOH|rcsb pdb:5X2R|rcsb pdb:5X2S|rcsb pdb:5X2T|rcsb pdb:5X2U|rcsb pdb:6BB5|rcsb pdb:6BNR|rcsb pdb:6BWP|rcsb pdb:6BWU|rcsb pdb:6DI4|rcsb pdb:6HAL|rcsb pdb:6HBW|rcsb pdb:6HK2|rcsb pdb:6KA9|rcsb pdb:6KAE|rcsb pdb:6KAH|rcsb pdb:6KAI|rcsb pdb:6KAO|rcsb pdb:6KAP|rcsb pdb:6KAQ|rcsb pdb:6KAR|rcsb pdb:6KAS|rcsb pdb:6KAT|rcsb pdb:4N7N|rcsb pdb:6KAU|rcsb pdb:4N7O|rcsb pdb:4N7P|rcsb pdb:6KAV|rcsb pdb:4N8T|rcsb pdb:6KYE|rcsb pdb:6L5V|rcsb pdb:6L5W|rcsb pdb:6L5X|rcsb pdb:6L5Y|rcsb pdb:6LCW|rcsb pdb:6LCX|rcsb pdb:4NI0|rcsb pdb:4NI1|rcsb pdb:4ROL|rcsb pdb:4ROM|rcsb pdb:4WJG|rcsb pdb:6NBC|rcsb pdb:6NBD|rcsb pdb:6NQ5|rcsb pdb:6TB2|rcsb pdb:6XD9|rcsb pdb:6XDT|rcsb pdb:6XE7|rcsb pdb:7AET|rcsb pdb:7AEV|rcsb pdb:7JJQ|rcsb pdb:7JXZ|rcsb pdb:7JY0|rcsb pdb:7JY1|rcsb pdb:7JY3|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-2168880|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:7AEU|refseq:NP_000508.1|refseq:NP_000549.1|rcsb pdb:1GBU|rcsb pdb:1GBV|rcsb pdb:1GLI|rcsb pdb:1GZX|rcsb pdb:1HAB|rcsb pdb:1HAC|rcsb pdb:1HBA|rcsb pdb:1HBB|rcsb pdb:1HBS|rcsb pdb:1HCO|rcsb pdb:1HDB|rcsb pdb:1HGA|rcsb pdb:1HGB|rcsb pdb:1HGC|rcsb pdb:1HHO|rcsb pdb:1IRD|rcsb pdb:1J3Y|rcsb pdb:1J3Z|rcsb pdb:1J40|rcsb pdb:1J41|rcsb pdb:1J7S|rcsb pdb:1J7W|rcsb pdb:1J7Y|rcsb pdb:1JY7|rcsb pdb:1K0Y|rcsb pdb:1K1K|rcsb pdb:1KD2|rcsb pdb:1LFL|rcsb pdb:1LFQ|rcsb pdb:1LFT|rcsb pdb:1LFV|rcsb pdb:1LFY|rcsb pdb:1LFZ|rcsb pdb:1LJW|rcsb pdb:1M9P|rcsb pdb:1MKO|rcsb pdb:1NEJ|rcsb pdb:1NIH|rcsb pdb:1NQP|rcsb pdb:1O1I|rcsb pdb:1O1J|rcsb pdb:1O1K|rcsb pdb:1O1L|rcsb pdb:1O1M|rcsb pdb:1O1N|rcsb pdb:1O1O|rcsb pdb:1O1P|rcsb pdb:1QI8|rcsb pdb:1QSH|rcsb pdb:1QSI|rcsb pdb:1QXD|rcsb pdb:1QXE|rcsb pdb:1R1X|rcsb pdb:1R1Y|rcsb pdb:1RPS|rcsb pdb:1RQ3|rcsb pdb:1RQ4|rcsb pdb:1RQA|rcsb pdb:1RVW|rcsb pdb:1SDK|rcsb pdb:1SDL|rcsb pdb:1SHR|rcsb pdb:1SI4|rcsb pdb:1THB|rcsb pdb:1UIW|rcsb pdb:1VWT|rcsb pdb:1XXT|rcsb pdb:1XY0|rcsb pdb:1XYE|rcsb pdb:1XZ2|rcsb pdb:1XZ4|rcsb pdb:1XZ5|rcsb pdb:1XZ7|rcsb pdb:1XZU|rcsb pdb:1XZV|rcsb pdb:1Y01|rcsb pdb:1Y09|rcsb pdb:1Y0A|rcsb pdb:1Y0C|rcsb pdb:1Y0D|rcsb pdb:1Y0T|rcsb pdb:1Y0W|rcsb pdb:1Y22|rcsb pdb:1Y2Z|rcsb pdb:1Y31|rcsb pdb:1Y35|rcsb pdb:1Y45|rcsb pdb:1Y46|rcsb pdb:1Y4B|rcsb pdb:1Y4F|rcsb pdb:1Y4G|rcsb pdb:1Y4P|rcsb pdb:1Y4Q|rcsb pdb:1Y4R|rcsb pdb:1Y4V|rcsb pdb:1Y5F|rcsb pdb:1Y5J|rcsb pdb:1Y5K|rcsb pdb:1Y7C|rcsb pdb:1Y7D|rcsb pdb:1Y7G|rcsb pdb:1Y7Z|rcsb pdb:1Y83|rcsb pdb:1Y85|rcsb pdb:1Y8W|rcsb pdb:1YDZ|rcsb pdb:1YE0|rcsb pdb:1YE1|rcsb pdb:1YE2|rcsb pdb:1YEN|rcsb pdb:1YEO|rcsb pdb:1YEQ|rcsb pdb:1YEU|rcsb pdb:1YEV|rcsb pdb:1YFF|rcsb pdb:1YG5|rcsb pdb:1YGD|rcsb pdb:1YGF|rcsb pdb:1YH9|rcsb pdb:1YHE|rcsb pdb:1YHR|rcsb pdb:1YIE|rcsb pdb:1YIH|dip:DIP-35199N pubmed:12072504(primary-reference) - - comment:A 20-mer oligonucleotide complementary to the 3' end of HPV16 E7 mRNA figure legend:Table 2, Figure 7A, 7B|comment:Human {alpha}1-globin 53-58 SAQIKG motif showed binding to radiolabeled HPV16 E7 mRNA by gel retardation experiments and this binding was suppressed by anti-p32Pabs. taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/13 2014/10/16 rogid:M4o0FF1DIrouBdyFXr4UtAlcjZw9606 crc64:6F22800B3F598BB1 intact-crc:4EFF1D58053CDB35 false sufficient binding region:53-58 - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P01966 ddbj/embl/genbank:K02718 intact:EBI-1397833|uniprotkb:A3KN13|uniprotkb:Q3SZE0|uniprotkb:Q9TTR9|uniprotkb:Q9TTS0|uniprotkb:Q9TTS1|ensembl:ENSBTAP00000037374 intact:EBI-1397994 psi-mi:hba_bovin(display_long)|uniprotkb:HBA(gene name)|psi-mi:HBA(display_short)|uniprotkb:Hemoglobin alpha chain(gene name synonym)|uniprotkb:Alpha-globin(gene name synonym) psi-mi:20-mer e7(display_short)|psi-mi:K02718(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Kanduc et al. (2002) pubmed:12072504 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1397845 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0324"(messenger rna) refseq:NP_001070890.2|refseq:XP_001788728.1|refseq:XP_003585623.1|ensembl:ENSBTAG00000051412(gene)|ensembl:ENSBTAT00000037545(transcript)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0098869"(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002338(Haemoglobin, alpha)|interpro:IPR002339(Haemoglobin, pi)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|rcsb pdb:1FSX|rcsb pdb:1G08|rcsb pdb:1G09|rcsb pdb:1G0A|rcsb pdb:1HDA|rcsb pdb:2QSP|rcsb pdb:2QSS|rcsb pdb:3CIU|rcsb pdb:3PI8|rcsb pdb:3PI9|rcsb pdb:3PIA|rcsb pdb:6IHX|rcsb pdb:6II1|reactome:R-BTA-1237044|reactome:R-BTA-1247673|reactome:R-BTA-2168880|reactome:R-BTA-9707564|reactome:R-BTA-9707616 pubmed:12072504(primary-reference) - - comment:A 20-mer oligonucleotide complementary to the 3' end of HPV16 E7 mRNA figure legend:Table 2, Figure 7A, 7B|comment:Bovine {alpha}1-globin 53-58 SAQVKG motif showed binding to radiolabeled HPV16 E7 mRNA by gel retardation experiments and this binding was suppressed by anti-p32Pabs. taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/13 2014/10/16 rogid:ciKu5JtregAURPM6ODifGNjWXBI9913 crc64:6F22800B3F598BB1 intact-crc:FB62204AD9451989 false sufficient binding region:53-58 - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P01946 ddbj/embl/genbank:K02718 intact:EBI-1209456|uniprotkb:P33583|uniprotkb:Q63243|uniprotkb:Q80XV2|uniprotkb:Q91V15|ensembl:ENSRNOP00000044233 intact:EBI-1397994 psi-mi:hba_rat(display_long)|uniprotkb:Hba1(gene name)|psi-mi:Hba1(display_short)|uniprotkb:Hba-a1(gene name synonym)|uniprotkb:Hemoglobin alpha-1/2 chain(gene name synonym)|uniprotkb:Alpha-1/2-globin(gene name synonym) psi-mi:20-mer e7(display_short)|psi-mi:K02718(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Kanduc et al. (2002) pubmed:12072504 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1397855 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0324"(messenger rna) rgd:2782|refseq:NP_001007723.1|refseq:NP_037228.1|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0009617"(response to bacterium)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0045202"(synapse)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0048821"(erythrocyte development)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0098869"(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002338(Haemoglobin, alpha)|interpro:IPR002339(Haemoglobin, pi)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|rcsb pdb:3DHT|rcsb pdb:3HF4|reactome:R-RNO-1237044|reactome:R-RNO-1247673|reactome:R-RNO-2168880|reactome:R-RNO-9707564|reactome:R-RNO-9707616|go:"GO:0001540"(amyloid-beta binding)|ensembl:ENSRNOG00000029886(gene)|ensembl:ENSRNOT00000051483(transcript) pubmed:12072504(primary-reference) - - comment:A 20-mer oligonucleotide complementary to the 3' end of HPV16 E7 mRNA figure legend:Table 2, Figure 7A, 7B|comment:Rat {alpha}1-globin 53-58 SAQVKA motif showed binding to radiolabeled HPV16 E7 mRNA by gel retardation experiments and this binding was suppressed by anti-p32Pabs. taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/13 2014/10/16 rogid:UtEMtpGnzOlmYQ3I9oqtG1dUbNI10116 crc64:6F22800B3F598BB1 intact-crc:A880E4BDD192AB00 false sufficient binding region:53-58 - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) ddbj/embl/genbank:K02718 uniprotkb:P68240 intact:EBI-1397994 intact:EBI-1397865|uniprotkb:P01970 psi-mi:20-mer e7(display_short)|psi-mi:K02718(display_long) psi-mi:hba_sheep(display_long)|uniprotkb:Hemoglobin alpha-1/2 chain(gene name synonym)|uniprotkb:Alpha-1/2-globin(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Kanduc et al. (2002) pubmed:12072504 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9940(sheep)|taxid:9940("Ovis aries (Sheep)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1397872 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0324"(messenger rna) psi-mi:"MI:0326"(protein) pubmed:12072504(primary-reference) interpro:IPR009050(Globin-like)|interpro:IPR000971(Globin, subset)|interpro:IPR002338(Haemoglobin, alpha)|interpro:IPR002339(Haemoglobin, pi)|rcsb pdb:2QU0|interpro:IPR012292(Globin)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding) - comment:A 20-mer oligonucleotide complementary to the 3' end of HPV16 E7 mRNA - figure legend:Table 2, Figure 7A, 7B|comment:Sheep {alpha}1-globin 53-58 SAQVKG motif showed binding to radiolabeled HPV16 E7 mRNA by gel retardation experiments and this binding was suppressed by anti-p32Pabs. taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/13 2014/10/16 crc64:6F22800B3F598BB1 rogid:ut2Z6WVWPXKiFLCXCaZWGBmwuzs9940 intact-crc:B4B6CB54291768F5 false - sufficient binding region:53-58 - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) ddbj/embl/genbank:K02718 uniprotkb:P01965 intact:EBI-1397994 intact:EBI-1397882 psi-mi:20-mer e7(display_short)|psi-mi:K02718(display_long) psi-mi:hba_pig(display_long)|uniprotkb:HBA(gene name)|psi-mi:HBA(display_short)|uniprotkb:Hemoglobin alpha chain(gene name synonym)|uniprotkb:Alpha-globin(gene name synonym) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Kanduc et al. (2002) pubmed:12072504 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1397890 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0324"(messenger rna) psi-mi:"MI:0326"(protein) pubmed:12072504(primary-reference) dip:DIP-38534N|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0098869"(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002338(Haemoglobin, alpha)|interpro:IPR002339(Haemoglobin, pi)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|rcsb pdb:1QPW|rcsb pdb:2PGH|rcsb pdb:4F4O - comment:A 20-mer oligonucleotide complementary to the 3' end of HPV16 E7 mRNA - figure legend:Table 2, Figure 7A, 7B|comment:Sheep {alpha}1-globin 52-57 SDQVKA motif showed binding to radiolabeled HPV16 E7 mRNA by gel retardation experiments and this binding was suppressed by anti-p32Pabs. taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/13 2014/10/16 crc64:6F22800B3F598BB1 rogid:0yVSo2x2Jzi6fBm7BwxjFr1doYk9823 intact-crc:51E0809F3E060956 false - sufficient binding region:52-57 - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P21871 ddbj/embl/genbank:K02718 intact:EBI-1397909|uniprotkb:O12986|uniprotkb:Q91249 intact:EBI-1397994 psi-mi:hba_colli(display_long)|uniprotkb:HBAA(gene name)|psi-mi:HBAA(display_short)|uniprotkb:Hemoglobin alpha-A chain(gene name synonym)|uniprotkb:Alpha-A-globin(gene name synonym) psi-mi:20-mer e7(display_short)|psi-mi:K02718(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Kanduc et al. (2002) pubmed:12072504 taxid:8932(colli)|taxid:8932("Columba livia (Domestic pigeon)") taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1397900 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0324"(messenger rna) refseq:XP_005508518.1|interpro:IPR009050(Globin-like)|interpro:IPR000971(Globin, subset)|interpro:IPR002338(Haemoglobin, alpha)|interpro:IPR002339(Haemoglobin, pi)|rcsb pdb:2R80|rcsb pdb:3DHR|rcsb pdb:3MJU|interpro:IPR012292(Globin)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding) pubmed:12072504(primary-reference) - - comment:A 20-mer oligonucleotide complementary to the 3' end of HPV16 E7 mRNA figure legend:Table 2, Figure 7A, 7B|comment:Pigeon {alpha}1-globin 53-58 SAQIKG motif showed binding to radiolabeled HPV16 E7 mRNA by gel retardation experiments and this binding was suppressed by anti-p32Pabs. taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/13 2014/10/16 rogid:r+sjbWgHEbttABEQn1dyCehGe3E8932 crc64:6F22800B3F598BB1 intact-crc:1ACB6FCB0B2D50FB false sufficient binding region:53-58 - - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) ddbj/embl/genbank:K02718 uniprotkb:P08729 intact:EBI-1397994 intact:EBI-297833|uniprotkb:Q92676|uniprotkb:Q9BUD8|uniprotkb:Q9Y3R7|ensembl:ENSP00000329243 psi-mi:20-mer e7(display_short)|psi-mi:K02718(display_long) psi-mi:k2c7_human(display_long)|uniprotkb:KRT7(gene name)|psi-mi:KRT7(display_short)|uniprotkb:SCL(gene name synonym)|uniprotkb:Cytokeratin-7(gene name synonym)|uniprotkb:Sarcolectin(gene name synonym)|uniprotkb:Keratin-7(gene name synonym)|uniprotkb:Type-II keratin Kb7(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Kanduc et al. (2002) pubmed:12072504 taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1397980 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0324"(messenger rna) psi-mi:"MI:0326"(protein) pubmed:12072504(primary-reference) ensembl:ENSG00000135480(gene)|ensembl:ENST00000331817(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0045095"(keratin filament)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P08729|rcsb pdb:4XIF|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_005547.3 - comment:A 20-mer oligonucleotide complementary to the 3' end of HPV16 E7 mRNA - figure legend:Figure 9|comment:The in-vivo interaction assay showed that there was binding of the 20-mer oligonucleotide with krt7. The assay was carried out using magnetic beads conjugated with the biotinylated 20-mer oligonucleotide 5'-TTATGGTTTCTGAGAACAGA, complementary to the 3' end of E7 mRNA, as bait. Oligonucleotide-coated beads were incubated with SiHa cell lysate and then eluted with the high-salt elution buffer. taxid:9606(human-siha)|taxid:9606(Homo sapiens SiHa cervical carcinoma cell line) - 2007/09/13 2014/10/16 crc64:6F22800B3F598BB1 rogid:/JagfI/WbHqqQXLNgQRXSJEPQpo9606 intact-crc:2D313932065D2496 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)