#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P26449 uniprotkb:P26309 intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W intact:EBI-4212|uniprotkb:D6VU31|ensemblfungi:YGL116W psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:cdc20_yeast(display_long)|uniprotkb:YGL116W(locus name)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:Cell division control protein 20(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fraschini et al. (2001) pubmed:11726501|imex:IM-19053|mint:MINT-5214838 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1270979|imex:IM-19053-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0 refseq:NP_011399.1|sgd:S000003084|dip:DIP-982N|mint:P26309|ensemblfungi:YGL116W(gene)|ensemblfungi:YGL116W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|reactome:R-SCE-141405|reactome:R-SCE-141430|reactome:R-SCE-174113|reactome:R-SCE-983168 go:"GO:0051320"(S phase) crc64:0BDFB8697935BCEB crc64:CCE7CD149C1F5ACF figure legend:Figure 1A, 2A, 3A|comment:The amount of the Bub3-Cdc20 complex varied during the cell cycle, peaking during G1-S transition, and did not exactly reflect the periodicity of Cdc20 protein levels.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/04 2014/10/16 rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292 rogid:8kkdOD/Z1G1Yf9TcjfvckVxhphk559292 intact-crc:1CCE9F896A1DF78B|rigid:TaB9FD6abGecDulFkYtRpJkQVVo false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26449 uniprotkb:P26309 intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W intact:EBI-4212|uniprotkb:D6VU31|ensemblfungi:YGL116W psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:cdc20_yeast(display_long)|uniprotkb:YGL116W(locus name)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:Cell division control protein 20(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fraschini et al. (2001) pubmed:11726501|imex:IM-19053|mint:MINT-5214838 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1270989|imex:IM-19053-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0 refseq:NP_011399.1|sgd:S000003084|dip:DIP-982N|mint:P26309|ensemblfungi:YGL116W(gene)|ensemblfungi:YGL116W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|reactome:R-SCE-141405|reactome:R-SCE-141430|reactome:R-SCE-174113|reactome:R-SCE-983168 - crc64:0BDFB8697935BCEB crc64:CCE7CD149C1F5ACF figure legend:Figure 1A.|comment:Interaction observed in cycling cells and when cells are arrested in G2 but not when arrested in G1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/04 2014/10/16 rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292 rogid:8kkdOD/Z1G1Yf9TcjfvckVxhphk559292 intact-crc:4FEB21AD8DF5DAD4|rigid:TaB9FD6abGecDulFkYtRpJkQVVo false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26449 uniprotkb:P26309 intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W intact:EBI-4212|uniprotkb:D6VU31|ensemblfungi:YGL116W psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:cdc20_yeast(display_long)|uniprotkb:YGL116W(locus name)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:Cell division control protein 20(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fraschini et al. (2001) pubmed:11726501|imex:IM-19053|mint:MINT-5214838 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1270999|imex:IM-19053-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0 refseq:NP_011399.1|sgd:S000003084|dip:DIP-982N|mint:P26309|ensemblfungi:YGL116W(gene)|ensemblfungi:YGL116W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|reactome:R-SCE-141405|reactome:R-SCE-141430|reactome:R-SCE-174113|reactome:R-SCE-983168 - crc64:0BDFB8697935BCEB crc64:CCE7CD149C1F5ACF figure legend:Figure 1B, 2B.|comment:Interaction increases when cells are in G2 arrest or by Mps1 which activates the kinetochore checkpoint in the absence of spindle damage|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/04 2014/10/16 rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292 rogid:8kkdOD/Z1G1Yf9TcjfvckVxhphk559292 intact-crc:2D6E10BF795E0356|rigid:3rJfuZc9WMxDjk5rnMxuxAm2gLM false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26449 uniprotkb:P40958 intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W intact:EBI-10362|ensemblfungi:YJL030W|uniprotkb:D6VWF2 psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:mad2_yeast(display_long)|uniprotkb:MAD2(gene name)|psi-mi:MAD2(display_short)|uniprotkb:J1256(orf name)|uniprotkb:YJL030W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fraschini et al. (2001) pubmed:11726501|imex:IM-19053|mint:MINT-5214838 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1270999|imex:IM-19053-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0 sgd:S000003567|ensemblfungi:YJL030W(gene)|ensemblfungi:YJL030W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051312"(chromosome decondensation)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-SCE-141405|reactome:R-SCE-141430|refseq:NP_012504.3|dip:DIP-815N|mint:P40958 - crc64:0BDFB8697935BCEB - figure legend:Figure 1B, 2B.|comment:Interaction increases when cells are in G2 arrest or by Mps1 which activates the kinetochore checkpoint in the absence of spindle damage|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/04 2014/10/16 rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292 rogid:0pxFckODTcklkGn+JcczltjSHRU559292 intact-crc:2D6E10BF795E0356|rigid:3rJfuZc9WMxDjk5rnMxuxAm2gLM false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26449 uniprotkb:P40957 intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W intact:EBI-10354|ensemblfungi:YGL086W|uniprotkb:D6VU58 psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:mad1_yeast(display_long)|uniprotkb:MAD1(gene name)|psi-mi:MAD1(display_short)|uniprotkb:Mitotic arrest deficient protein 1(gene name synonym)|uniprotkb:YGL086W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fraschini et al. (2001) pubmed:11726501|imex:IM-19053|mint:MINT-5214838 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1270999|imex:IM-19053-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0 sgd:S000003054|ensemblfungi:YGL086W(gene)|ensemblfungi:YGL086W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1901925"(negative regulation of protein import into nucleus during spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|refseq:NP_011429.3|dip:DIP-293N|mint:P40957 - crc64:0BDFB8697935BCEB - figure legend:Figure 1B, 2B.|comment:Interaction increases when cells are in G2 arrest or by Mps1 which activates the kinetochore checkpoint in the absence of spindle damage|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/04 2014/10/16 rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292 rogid:KN5bSe+qhWpvc7W6Sh2IolgtLXE559292 intact-crc:2D6E10BF795E0356|rigid:3rJfuZc9WMxDjk5rnMxuxAm2gLM false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26309 uniprotkb:P40958 intact:EBI-4212|uniprotkb:D6VU31|ensemblfungi:YGL116W intact:EBI-10362|ensemblfungi:YJL030W|uniprotkb:D6VWF2 psi-mi:cdc20_yeast(display_long)|uniprotkb:YGL116W(locus name)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:Cell division control protein 20(gene name synonym) psi-mi:mad2_yeast(display_long)|uniprotkb:MAD2(gene name)|psi-mi:MAD2(display_short)|uniprotkb:J1256(orf name)|uniprotkb:YJL030W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fraschini et al. (2001) pubmed:11726501|imex:IM-19053|mint:MINT-5214838 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1271011|imex:IM-19053-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011399.1|sgd:S000003084|dip:DIP-982N|mint:P26309|ensemblfungi:YGL116W(gene)|ensemblfungi:YGL116W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|reactome:R-SCE-141405|reactome:R-SCE-141430|reactome:R-SCE-174113|reactome:R-SCE-983168 sgd:S000003567|ensemblfungi:YJL030W(gene)|ensemblfungi:YJL030W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051312"(chromosome decondensation)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-SCE-141405|reactome:R-SCE-141430|refseq:NP_012504.3|dip:DIP-815N|mint:P40958 - crc64:CCE7CD149C1F5ACF - figure legend:Figure 1B.|comment:Interaction increase when cells are in G2 arrest.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/04 2014/10/16 rogid:8kkdOD/Z1G1Yf9TcjfvckVxhphk559292 rogid:0pxFckODTcklkGn+JcczltjSHRU559292 intact-crc:ECD2296560ECD773|rigid:uNYXI37+8gHQf/omKeHpT/u+RAc false myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26309 uniprotkb:P26449 intact:EBI-4212|uniprotkb:D6VU31|ensemblfungi:YGL116W intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W psi-mi:cdc20_yeast(display_long)|uniprotkb:YGL116W(locus name)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:Cell division control protein 20(gene name synonym) psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fraschini et al. (2001) pubmed:11726501|imex:IM-19053|mint:MINT-5214838 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1271011|imex:IM-19053-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011399.1|sgd:S000003084|dip:DIP-982N|mint:P26309|ensemblfungi:YGL116W(gene)|ensemblfungi:YGL116W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|reactome:R-SCE-141405|reactome:R-SCE-141430|reactome:R-SCE-174113|reactome:R-SCE-983168 refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0 - crc64:CCE7CD149C1F5ACF crc64:0BDFB8697935BCEB figure legend:Figure 1B.|comment:Interaction increase when cells are in G2 arrest.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/04 2014/10/16 rogid:8kkdOD/Z1G1Yf9TcjfvckVxhphk559292 rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292 intact-crc:ECD2296560ECD773|rigid:uNYXI37+8gHQf/omKeHpT/u+RAc false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26309 uniprotkb:P47074 intact:EBI-4212|uniprotkb:D6VU31|ensemblfungi:YGL116W intact:EBI-10369|ensemblfungi:YJL013C|uniprotkb:D6VWG4 psi-mi:cdc20_yeast(display_long)|uniprotkb:YGL116W(locus name)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:Cell division control protein 20(gene name synonym) psi-mi:mad3_yeast(display_long)|uniprotkb:MAD3(gene name)|psi-mi:MAD3(display_short)|uniprotkb:YJL013C(locus name)|uniprotkb:J1341(orf name)|uniprotkb:Mitotic MAD3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fraschini et al. (2001) pubmed:11726501|imex:IM-19053|mint:MINT-5214838 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1271142|imex:IM-19053-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011399.1|sgd:S000003084|dip:DIP-982N|mint:P26309|ensemblfungi:YGL116W(gene)|ensemblfungi:YGL116W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|reactome:R-SCE-141405|reactome:R-SCE-141430|reactome:R-SCE-174113|reactome:R-SCE-983168 sgd:S000003550|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0051301"(cell division)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR012572(Mad3-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|rcsb pdb:2I3T|ensemblfungi:YJL013C(gene)|ensemblfungi:YJL013C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0032837"(distributive segregation)|refseq:NP_012521.3|dip:DIP-1268N - crc64:CCE7CD149C1F5ACF crc64:36550249D81BB6D1 figure legend:Figure 3B, 5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/04 2014/10/16 rogid:8kkdOD/Z1G1Yf9TcjfvckVxhphk559292 rogid:lyE7pycs775JBy2fvm2J861azlg559292 intact-crc:2F9593CD9AE0A2FF|rigid:GjPczuBPZw4IUDCDrCiihyb/zss false myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26309 uniprotkb:P40958 intact:EBI-4212|uniprotkb:D6VU31|ensemblfungi:YGL116W intact:EBI-10362|ensemblfungi:YJL030W|uniprotkb:D6VWF2 psi-mi:cdc20_yeast(display_long)|uniprotkb:YGL116W(locus name)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:Cell division control protein 20(gene name synonym) psi-mi:mad2_yeast(display_long)|uniprotkb:MAD2(gene name)|psi-mi:MAD2(display_short)|uniprotkb:J1256(orf name)|uniprotkb:YJL030W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fraschini et al. (2001) pubmed:11726501|imex:IM-19053|mint:MINT-5214838 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1271142|imex:IM-19053-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011399.1|sgd:S000003084|dip:DIP-982N|mint:P26309|ensemblfungi:YGL116W(gene)|ensemblfungi:YGL116W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|reactome:R-SCE-141405|reactome:R-SCE-141430|reactome:R-SCE-174113|reactome:R-SCE-983168 sgd:S000003567|ensemblfungi:YJL030W(gene)|ensemblfungi:YJL030W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051312"(chromosome decondensation)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-SCE-141405|reactome:R-SCE-141430|refseq:NP_012504.3|dip:DIP-815N|mint:P40958 - crc64:CCE7CD149C1F5ACF - figure legend:Figure 3B, 5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/04 2014/10/16 rogid:8kkdOD/Z1G1Yf9TcjfvckVxhphk559292 rogid:0pxFckODTcklkGn+JcczltjSHRU559292 intact-crc:2F9593CD9AE0A2FF|rigid:GjPczuBPZw4IUDCDrCiihyb/zss false myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26309 uniprotkb:P26449 intact:EBI-4212|uniprotkb:D6VU31|ensemblfungi:YGL116W intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W psi-mi:cdc20_yeast(display_long)|uniprotkb:YGL116W(locus name)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:Cell division control protein 20(gene name synonym) psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fraschini et al. (2001) pubmed:11726501|imex:IM-19053|mint:MINT-5214838 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1271142|imex:IM-19053-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011399.1|sgd:S000003084|dip:DIP-982N|mint:P26309|ensemblfungi:YGL116W(gene)|ensemblfungi:YGL116W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|reactome:R-SCE-141405|reactome:R-SCE-141430|reactome:R-SCE-174113|reactome:R-SCE-983168 refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0 - crc64:CCE7CD149C1F5ACF crc64:0BDFB8697935BCEB figure legend:Figure 3B, 5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/04 2014/10/16 rogid:8kkdOD/Z1G1Yf9TcjfvckVxhphk559292 rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292 intact-crc:2F9593CD9AE0A2FF|rigid:GjPczuBPZw4IUDCDrCiihyb/zss false myc tag:?-? ha tag:?-?|mutation decreasing interaction:31-31,120-120 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26449 uniprotkb:P47074 intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W intact:EBI-10369|ensemblfungi:YJL013C|uniprotkb:D6VWG4 psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:mad3_yeast(display_long)|uniprotkb:MAD3(gene name)|psi-mi:MAD3(display_short)|uniprotkb:YJL013C(locus name)|uniprotkb:J1341(orf name)|uniprotkb:Mitotic MAD3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fraschini et al. (2001) pubmed:11726501|imex:IM-19053|mint:MINT-5214838 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1271180|imex:IM-19053-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0 sgd:S000003550|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0051301"(cell division)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR012572(Mad3-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|rcsb pdb:2I3T|ensemblfungi:YJL013C(gene)|ensemblfungi:YJL013C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0032837"(distributive segregation)|refseq:NP_012521.3|dip:DIP-1268N - crc64:0BDFB8697935BCEB crc64:36550249D81BB6D1 figure legend:Figure 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/04 2014/10/16 rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292 rogid:lyE7pycs775JBy2fvm2J861azlg559292 intact-crc:29CF2F5EC4F56838|rigid:GjPczuBPZw4IUDCDrCiihyb/zss false ha tag:?-?|mutation decreasing interaction:31-31,120-120 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26449 uniprotkb:P40958 intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W intact:EBI-10362|ensemblfungi:YJL030W|uniprotkb:D6VWF2 psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:mad2_yeast(display_long)|uniprotkb:MAD2(gene name)|psi-mi:MAD2(display_short)|uniprotkb:J1256(orf name)|uniprotkb:YJL030W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fraschini et al. (2001) pubmed:11726501|imex:IM-19053|mint:MINT-5214838 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1271180|imex:IM-19053-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0 sgd:S000003567|ensemblfungi:YJL030W(gene)|ensemblfungi:YJL030W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051312"(chromosome decondensation)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-SCE-141405|reactome:R-SCE-141430|refseq:NP_012504.3|dip:DIP-815N|mint:P40958 - crc64:0BDFB8697935BCEB - figure legend:Figure 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/04 2014/10/16 rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292 rogid:0pxFckODTcklkGn+JcczltjSHRU559292 intact-crc:29CF2F5EC4F56838|rigid:GjPczuBPZw4IUDCDrCiihyb/zss false ha tag:?-?|mutation decreasing interaction:31-31,120-120 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26449 uniprotkb:P26309 intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W intact:EBI-4212|uniprotkb:D6VU31|ensemblfungi:YGL116W psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:cdc20_yeast(display_long)|uniprotkb:YGL116W(locus name)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:Cell division control protein 20(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Fraschini et al. (2001) pubmed:11726501|imex:IM-19053|mint:MINT-5214838 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1271180|imex:IM-19053-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0 refseq:NP_011399.1|sgd:S000003084|dip:DIP-982N|mint:P26309|ensemblfungi:YGL116W(gene)|ensemblfungi:YGL116W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|reactome:R-SCE-141405|reactome:R-SCE-141430|reactome:R-SCE-174113|reactome:R-SCE-983168 - crc64:0BDFB8697935BCEB crc64:CCE7CD149C1F5ACF figure legend:Figure 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/04 2014/10/16 rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292 rogid:8kkdOD/Z1G1Yf9TcjfvckVxhphk559292 intact-crc:29CF2F5EC4F56838|rigid:GjPczuBPZw4IUDCDrCiihyb/zss false ha tag:?-?|mutation decreasing interaction:31-31,120-120 myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P41695 uniprotkb:P26449 intact:EBI-3816|uniprotkb:D6VUX1|ensemblfungi:YGR188C intact:EBI-3830|uniprotkb:D6W292|ensemblfungi:YOR026W psi-mi:bub1_yeast(display_long)|uniprotkb:YGR188C(locus name)|uniprotkb:G7542(orf name)|uniprotkb:BUB1(gene name)|psi-mi:BUB1(display_short) psi-mi:bub3_yeast(display_long)|uniprotkb:OR26.16(orf name)|uniprotkb:YOR026W(locus name)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:"MI:0071"(molecular sieving) Fraschini et al. (2001) pubmed:11726501|imex:IM-19053|mint:MINT-5214838 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1271160|imex:IM-19053-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003420|refseq:NP_011704.3|dip:DIP-2236N|mint:P41695|ensemblfungi:YGR188C(gene)|ensemblfungi:YGR188C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0016236"(macroautophagy)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0034508"(centromere complex assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012572(Mad3-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2I3S|rcsb pdb:3ESL|rcsb pdb:4BL0|reactome:R-SCE-141430 refseq:NP_014669.1|sgd:S000005552|reactome:R-SCE-141430|dip:DIP-1219N|ensemblfungi:YOR026W(gene)|ensemblfungi:YOR026W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:1U4C|rcsb pdb:1YFQ|rcsb pdb:2I3S|rcsb pdb:2I3T|rcsb pdb:4BL0 - crc64:6D76FC980775D3F9 crc64:0BDFB8697935BCEB figure legend:Figure 4A|comment:Authors believe this may comprise two separate complexes, both with MW = 670kDa.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/04 2014/10/16 rogid:O4X/wXB2iXRdSVxIGA9nG1Sj5dI559292 rogid:y8P+TfgWS+dySWQDW7eo6YOGjwU559292 intact-crc:12D430D9DE909D67|rigid:3DiRAybmUTeEBc87/FG6zp7701c false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P41695 uniprotkb:P26309 intact:EBI-3816|uniprotkb:D6VUX1|ensemblfungi:YGR188C intact:EBI-4212|uniprotkb:D6VU31|ensemblfungi:YGL116W psi-mi:bub1_yeast(display_long)|uniprotkb:YGR188C(locus name)|uniprotkb:G7542(orf name)|uniprotkb:BUB1(gene name)|psi-mi:BUB1(display_short) psi-mi:cdc20_yeast(display_long)|uniprotkb:YGL116W(locus name)|uniprotkb:CDC20(gene name)|psi-mi:CDC20(display_short)|uniprotkb:Cell division control protein 20(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Fraschini et al. (2001) pubmed:11726501|imex:IM-19053|mint:MINT-5214838 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1271160|imex:IM-19053-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003420|refseq:NP_011704.3|dip:DIP-2236N|mint:P41695|ensemblfungi:YGR188C(gene)|ensemblfungi:YGR188C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0016236"(macroautophagy)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0034508"(centromere complex assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012572(Mad3-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2I3S|rcsb pdb:3ESL|rcsb pdb:4BL0|reactome:R-SCE-141430 refseq:NP_011399.1|sgd:S000003084|dip:DIP-982N|mint:P26309|ensemblfungi:YGL116W(gene)|ensemblfungi:YGL116W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1905786"(positive regulation of anaphase-promoting complex-dependent catabolic process)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR033010|reactome:R-SCE-141405|reactome:R-SCE-141430|reactome:R-SCE-174113|reactome:R-SCE-983168 - crc64:6D76FC980775D3F9 crc64:CCE7CD149C1F5ACF figure legend:Figure 4A|comment:Authors believe this may comprise two separate complexes, both with MW = 670kDa.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/04 2014/10/16 rogid:O4X/wXB2iXRdSVxIGA9nG1Sj5dI559292 rogid:8kkdOD/Z1G1Yf9TcjfvckVxhphk559292 intact-crc:12D430D9DE909D67|rigid:3DiRAybmUTeEBc87/FG6zp7701c false myc tag:?-? myc tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P41695 uniprotkb:P40957 intact:EBI-3816|uniprotkb:D6VUX1|ensemblfungi:YGR188C intact:EBI-10354|ensemblfungi:YGL086W|uniprotkb:D6VU58 psi-mi:bub1_yeast(display_long)|uniprotkb:YGR188C(locus name)|uniprotkb:G7542(orf name)|uniprotkb:BUB1(gene name)|psi-mi:BUB1(display_short) psi-mi:mad1_yeast(display_long)|uniprotkb:MAD1(gene name)|psi-mi:MAD1(display_short)|uniprotkb:Mitotic arrest deficient protein 1(gene name synonym)|uniprotkb:YGL086W(locus name) psi-mi:"MI:0071"(molecular sieving) Fraschini et al. (2001) pubmed:11726501|imex:IM-19053|mint:MINT-5214838 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1271160|imex:IM-19053-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003420|refseq:NP_011704.3|dip:DIP-2236N|mint:P41695|ensemblfungi:YGR188C(gene)|ensemblfungi:YGR188C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0016236"(macroautophagy)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0034508"(centromere complex assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012572(Mad3-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2I3S|rcsb pdb:3ESL|rcsb pdb:4BL0|reactome:R-SCE-141430 sgd:S000003054|ensemblfungi:YGL086W(gene)|ensemblfungi:YGL086W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1901925"(negative regulation of protein import into nucleus during spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|refseq:NP_011429.3|dip:DIP-293N|mint:P40957 - crc64:6D76FC980775D3F9 - figure legend:Figure 4A|comment:Authors believe this may comprise two separate complexes, both with MW = 670kDa.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/04 2014/10/16 rogid:O4X/wXB2iXRdSVxIGA9nG1Sj5dI559292 rogid:KN5bSe+qhWpvc7W6Sh2IolgtLXE559292 intact-crc:12D430D9DE909D67|rigid:3DiRAybmUTeEBc87/FG6zp7701c false myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P41695 uniprotkb:P40958 intact:EBI-3816|uniprotkb:D6VUX1|ensemblfungi:YGR188C intact:EBI-10362|ensemblfungi:YJL030W|uniprotkb:D6VWF2 psi-mi:bub1_yeast(display_long)|uniprotkb:YGR188C(locus name)|uniprotkb:G7542(orf name)|uniprotkb:BUB1(gene name)|psi-mi:BUB1(display_short) psi-mi:mad2_yeast(display_long)|uniprotkb:MAD2(gene name)|psi-mi:MAD2(display_short)|uniprotkb:J1256(orf name)|uniprotkb:YJL030W(locus name) psi-mi:"MI:0071"(molecular sieving) Fraschini et al. (2001) pubmed:11726501|imex:IM-19053|mint:MINT-5214838 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1271160|imex:IM-19053-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003420|refseq:NP_011704.3|dip:DIP-2236N|mint:P41695|ensemblfungi:YGR188C(gene)|ensemblfungi:YGR188C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0016236"(macroautophagy)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0034508"(centromere complex assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012572(Mad3-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2I3S|rcsb pdb:3ESL|rcsb pdb:4BL0|reactome:R-SCE-141430 sgd:S000003567|ensemblfungi:YJL030W(gene)|ensemblfungi:YJL030W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051312"(chromosome decondensation)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR027097|interpro:IPR036570|reactome:R-SCE-141405|reactome:R-SCE-141430|refseq:NP_012504.3|dip:DIP-815N|mint:P40958 - crc64:6D76FC980775D3F9 - figure legend:Figure 4A|comment:Authors believe this may comprise two separate complexes, both with MW = 670kDa.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/04 2014/10/16 rogid:O4X/wXB2iXRdSVxIGA9nG1Sj5dI559292 rogid:0pxFckODTcklkGn+JcczltjSHRU559292 intact-crc:12D430D9DE909D67|rigid:3DiRAybmUTeEBc87/FG6zp7701c false myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P41695 uniprotkb:P47074 intact:EBI-3816|uniprotkb:D6VUX1|ensemblfungi:YGR188C intact:EBI-10369|ensemblfungi:YJL013C|uniprotkb:D6VWG4 psi-mi:bub1_yeast(display_long)|uniprotkb:YGR188C(locus name)|uniprotkb:G7542(orf name)|uniprotkb:BUB1(gene name)|psi-mi:BUB1(display_short) psi-mi:mad3_yeast(display_long)|uniprotkb:MAD3(gene name)|psi-mi:MAD3(display_short)|uniprotkb:YJL013C(locus name)|uniprotkb:J1341(orf name)|uniprotkb:Mitotic MAD3 protein(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Fraschini et al. (2001) pubmed:11726501|imex:IM-19053|mint:MINT-5214838 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1271160|imex:IM-19053-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003420|refseq:NP_011704.3|dip:DIP-2236N|mint:P41695|ensemblfungi:YGR188C(gene)|ensemblfungi:YGR188C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0016236"(macroautophagy)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0034508"(centromere complex assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012572(Mad3-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2I3S|rcsb pdb:3ESL|rcsb pdb:4BL0|reactome:R-SCE-141430 sgd:S000003550|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0051301"(cell division)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR012572(Mad3-like)|interpro:IPR013212(Mad3/BUB1 homology region 1)|interpro:IPR015661(Mitotic checkpoint serine/threonine protein kinase, Bub1)|rcsb pdb:2I3T|ensemblfungi:YJL013C(gene)|ensemblfungi:YJL013C_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0032837"(distributive segregation)|refseq:NP_012521.3|dip:DIP-1268N - crc64:6D76FC980775D3F9 crc64:36550249D81BB6D1 figure legend:Figure 4A|comment:Authors believe this may comprise two separate complexes, both with MW = 670kDa.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/04 2014/10/16 rogid:O4X/wXB2iXRdSVxIGA9nG1Sj5dI559292 rogid:lyE7pycs775JBy2fvm2J861azlg559292 intact-crc:12D430D9DE909D67|rigid:3DiRAybmUTeEBc87/FG6zp7701c false myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)