#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P28241	uniprotkb:P28834	intact:EBI-8883|ensemblfungi:YOR136W|uniprotkb:D6W2J3	intact:EBI-8878|ensemblfungi:YNL037C|uniprotkb:D6W1E2	psi-mi:idh2_yeast(display_long)|uniprotkb:Isocitric dehydrogenase(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH"(gene name synonym)|uniprotkb:IDH2(gene name)|psi-mi:IDH2(display_short)|uniprotkb:YOR136W(locus name)|uniprotkb:YOR3326W(orf name)|uniprotkb:O3326(orf name)	psi-mi:idh1_yeast(display_long)|uniprotkb:IDH1(gene name)|psi-mi:IDH1(display_short)|uniprotkb:YNL037C(locus name)|uniprotkb:N2690(orf name)|uniprotkb:Isocitric dehydrogenase(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH"(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Panisko et al. (2001)	pubmed:11042198|imex:IM-18927	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1211152|imex:IM-18927-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOR136W(gene)|ensemblfungi:YOR136W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005962"("mitochondrial isocitrate dehydrogenase complex (NAD+)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|rcsb pdb:3BLV|rcsb pdb:3BLW|rcsb pdb:3BLX|reactome:R-SCE-71403|refseq:NP_014779.1|sgd:S000005662|mint:P28241|dip:DIP-4296N	ensemblfungi:YNL037C(gene)|ensemblfungi:YNL037C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005962"("mitochondrial isocitrate dehydrogenase complex (NAD+)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|rcsb pdb:3BLV|rcsb pdb:3BLW|rcsb pdb:3BLX|reactome:R-SCE-71403|refseq:NP_014361.1|sgd:S000004982|mint:P28834|dip:DIP-4376N	-	crc64:3A48C999776CE373	crc64:0932E7B3CD685240	figure legend:Table 1|comment:Results confirmed using alternative sets of reporter genes.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/03/06	2014/10/16	rogid:WauwJ5h18OgV9y8bceAXMKLrm0g559292	rogid:oCOB3vaHYyiEYHcF8b/1PnYocQQ559292	intact-crc:8F524D7D023A6E9A|rigid:fgzKFqgYFg696hk72h+K4pWmtmQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28241	uniprotkb:P28834	intact:EBI-8883|ensemblfungi:YOR136W|uniprotkb:D6W2J3	intact:EBI-8878|ensemblfungi:YNL037C|uniprotkb:D6W1E2	psi-mi:idh2_yeast(display_long)|uniprotkb:Isocitric dehydrogenase(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH"(gene name synonym)|uniprotkb:IDH2(gene name)|psi-mi:IDH2(display_short)|uniprotkb:YOR136W(locus name)|uniprotkb:YOR3326W(orf name)|uniprotkb:O3326(orf name)	psi-mi:idh1_yeast(display_long)|uniprotkb:IDH1(gene name)|psi-mi:IDH1(display_short)|uniprotkb:YNL037C(locus name)|uniprotkb:N2690(orf name)|uniprotkb:Isocitric dehydrogenase(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH"(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Panisko et al. (2001)	pubmed:11042198|imex:IM-18927	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1211175|imex:IM-18927-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOR136W(gene)|ensemblfungi:YOR136W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005962"("mitochondrial isocitrate dehydrogenase complex (NAD+)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|rcsb pdb:3BLV|rcsb pdb:3BLW|rcsb pdb:3BLX|reactome:R-SCE-71403|refseq:NP_014779.1|sgd:S000005662|mint:P28241|dip:DIP-4296N	ensemblfungi:YNL037C(gene)|ensemblfungi:YNL037C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005962"("mitochondrial isocitrate dehydrogenase complex (NAD+)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|rcsb pdb:3BLV|rcsb pdb:3BLW|rcsb pdb:3BLX|reactome:R-SCE-71403|refseq:NP_014361.1|sgd:S000004982|mint:P28834|dip:DIP-4376N	-	crc64:3A48C999776CE373	crc64:0932E7B3CD685240	figure legend:Table 1|comment:Results confirmed using alternative sets of reporter genes.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/03/06	2014/10/16	rogid:WauwJ5h18OgV9y8bceAXMKLrm0g559292	rogid:oCOB3vaHYyiEYHcF8b/1PnYocQQ559292	intact-crc:6C4E45AE3466C430|rigid:fgzKFqgYFg696hk72h+K4pWmtmQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28241	uniprotkb:P28834	intact:EBI-8883|ensemblfungi:YOR136W|uniprotkb:D6W2J3	intact:EBI-8878|ensemblfungi:YNL037C|uniprotkb:D6W1E2	psi-mi:idh2_yeast(display_long)|uniprotkb:Isocitric dehydrogenase(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH"(gene name synonym)|uniprotkb:IDH2(gene name)|psi-mi:IDH2(display_short)|uniprotkb:YOR136W(locus name)|uniprotkb:YOR3326W(orf name)|uniprotkb:O3326(orf name)	psi-mi:idh1_yeast(display_long)|uniprotkb:IDH1(gene name)|psi-mi:IDH1(display_short)|uniprotkb:YNL037C(locus name)|uniprotkb:N2690(orf name)|uniprotkb:Isocitric dehydrogenase(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Panisko et al. (2001)	pubmed:11042198|imex:IM-18927	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1211197|imex:IM-18927-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOR136W(gene)|ensemblfungi:YOR136W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005962"("mitochondrial isocitrate dehydrogenase complex (NAD+)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|rcsb pdb:3BLV|rcsb pdb:3BLW|rcsb pdb:3BLX|reactome:R-SCE-71403|refseq:NP_014779.1|sgd:S000005662|mint:P28241|dip:DIP-4296N	ensemblfungi:YNL037C(gene)|ensemblfungi:YNL037C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005962"("mitochondrial isocitrate dehydrogenase complex (NAD+)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|rcsb pdb:3BLV|rcsb pdb:3BLW|rcsb pdb:3BLX|reactome:R-SCE-71403|refseq:NP_014361.1|sgd:S000004982|mint:P28834|dip:DIP-4376N	-	crc64:3A48C999776CE373	crc64:0932E7B3CD685240	figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/03/06	2014/10/16	rogid:WauwJ5h18OgV9y8bceAXMKLrm0g559292	rogid:oCOB3vaHYyiEYHcF8b/1PnYocQQ559292	intact-crc:71046D51693BD098|rigid:fgzKFqgYFg696hk72h+K4pWmtmQ	false	-	his tag:c-c	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
uniprotkb:P28241	uniprotkb:P28834	intact:EBI-8883|ensemblfungi:YOR136W|uniprotkb:D6W2J3	intact:EBI-8878|ensemblfungi:YNL037C|uniprotkb:D6W1E2	psi-mi:idh2_yeast(display_long)|uniprotkb:Isocitric dehydrogenase(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH"(gene name synonym)|uniprotkb:IDH2(gene name)|psi-mi:IDH2(display_short)|uniprotkb:YOR136W(locus name)|uniprotkb:YOR3326W(orf name)|uniprotkb:O3326(orf name)	psi-mi:idh1_yeast(display_long)|uniprotkb:IDH1(gene name)|psi-mi:IDH1(display_short)|uniprotkb:YNL037C(locus name)|uniprotkb:N2690(orf name)|uniprotkb:Isocitric dehydrogenase(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Panisko et al. (2001)	pubmed:11042198|imex:IM-18927	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1211205|imex:IM-18927-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOR136W(gene)|ensemblfungi:YOR136W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005962"("mitochondrial isocitrate dehydrogenase complex (NAD+)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|rcsb pdb:3BLV|rcsb pdb:3BLW|rcsb pdb:3BLX|reactome:R-SCE-71403|refseq:NP_014779.1|sgd:S000005662|mint:P28241|dip:DIP-4296N	ensemblfungi:YNL037C(gene)|ensemblfungi:YNL037C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005962"("mitochondrial isocitrate dehydrogenase complex (NAD+)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|rcsb pdb:3BLV|rcsb pdb:3BLW|rcsb pdb:3BLX|reactome:R-SCE-71403|refseq:NP_014361.1|sgd:S000004982|mint:P28834|dip:DIP-4376N	-	crc64:3A48C999776CE373	crc64:0932E7B3CD685240	figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/03/06	2014/10/16	rogid:WauwJ5h18OgV9y8bceAXMKLrm0g559292	rogid:oCOB3vaHYyiEYHcF8b/1PnYocQQ559292	intact-crc:2710B9AA349F2753|rigid:fgzKFqgYFg696hk72h+K4pWmtmQ	false	his tag:c-c	-	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)