#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P32389	uniprotkb:P40573	intact:EBI-10757|uniprotkb:D6W176	intact:EBI-11503|uniprotkb:D6VVU7|ensemblfungi:YIR017C	psi-mi:met4_yeast(display_long)|uniprotkb:MET4(gene name)|psi-mi:MET4(display_short)|uniprotkb:YNL103W(locus name)|uniprotkb:N2177(orf name)|uniprotkb:Methionine-requiring protein 4(gene name synonym)	psi-mi:met28_yeast(display_long)|uniprotkb:MET28(gene name)|psi-mi:MET28(display_short)|uniprotkb:Methionine-requiring protein 28(gene name synonym)|uniprotkb:YIR017C(locus name)	psi-mi:"MI:0018"(two hybrid)	Blaiseau et al. (1998)	pubmed:9799240|imex:IM-19861	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-906236|imex:IM-19861-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005047|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0089713"(Cbf1-Met4-Met28 complex)|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0042802"(identical protein binding)|refseq:NP_014296.4|mint:P32389|dip:DIP-2241N	ensemblfungi:YIR017C(gene)|ensemblfungi:YIR017C_mRNA(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0031335"(regulation of sulfur amino acid metabolic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0089713"(Cbf1-Met4-Met28 complex)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|refseq:NP_012282.3|sgd:S000001456|dip:DIP-2242N	-	crc64:D65745E1FA40C09D	-	comment:Deletion of the bZIP domain of Met4 also significantly decreases the interaction between Met4 and Met31 or Met32.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/16	2014/10/16	rogid:SpxM+SnEmiw+uQlCEGZSto/zduw559292	rogid:vPHCC2NoSmWfllEyCnMu+sIrGko559292	intact-crc:440442FE446BCA25|rigid:CkN9gLP5LnqtfdOh1pV3zfeChqM	false	necessary binding region:617-667	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03081	uniprotkb:P32389	intact:EBI-11511|uniprotkb:D6W3X6|ensemblfungi:YPL038W	intact:EBI-10757|uniprotkb:D6W176	psi-mi:met31_yeast(display_long)|uniprotkb:MET31(gene name)|psi-mi:MET31(display_short)|uniprotkb:YPL038W(locus name)|uniprotkb:P7102.12(orf name)|uniprotkb:Methionine-requiring protein 31(gene name synonym)	psi-mi:met4_yeast(display_long)|uniprotkb:MET4(gene name)|psi-mi:MET4(display_short)|uniprotkb:YNL103W(locus name)|uniprotkb:N2177(orf name)|uniprotkb:Methionine-requiring protein 4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Blaiseau et al. (1998)	pubmed:9799240|imex:IM-19861	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-906242|imex:IM-19861-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPL038W(gene)|ensemblfungi:YPL038W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031335"(regulation of sulfur amino acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|refseq:NP_015287.1|sgd:S000005959|dip:DIP-1445N	sgd:S000005047|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0089713"(Cbf1-Met4-Met28 complex)|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0042802"(identical protein binding)|refseq:NP_014296.4|mint:P32389|dip:DIP-2241N	-	crc64:BAF5C76E24A25AEE	crc64:D65745E1FA40C09D	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/16	2014/10/16	rogid:J1vUsOuTF29s5/CKX4QRh+EP6Zg559292	rogid:SpxM+SnEmiw+uQlCEGZSto/zduw559292	intact-crc:8EC8F279519CC19F|rigid:vJ4L0cEsQAkz9YRX15+BFc6cnmE	false	-	necessary binding region:375-430	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12041	uniprotkb:P32389	intact:EBI-11519|uniprotkb:D6VSN3|ensemblfungi:YDR253C	intact:EBI-10757|uniprotkb:D6W176	psi-mi:met32_yeast(display_long)|uniprotkb:MET32(gene name)|psi-mi:MET32(display_short)|uniprotkb:YDR253C(locus name)|uniprotkb:YD9320A.03C(orf name)|uniprotkb:Methionine-requiring protein 32(gene name synonym)	psi-mi:met4_yeast(display_long)|uniprotkb:MET4(gene name)|psi-mi:MET4(display_short)|uniprotkb:YNL103W(locus name)|uniprotkb:N2177(orf name)|uniprotkb:Methionine-requiring protein 4(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Blaiseau et al. (1998)	pubmed:9799240|imex:IM-19861	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-906253|imex:IM-19861-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR253C(gene)|ensemblfungi:YDR253C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0031335"(regulation of sulfur amino acid metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:NP_010539.1|sgd:S000002661|dip:DIP-2411N	sgd:S000005047|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0089713"(Cbf1-Met4-Met28 complex)|go:"GO:0000096"(sulfur amino acid metabolic process)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0042802"(identical protein binding)|refseq:NP_014296.4|mint:P32389|dip:DIP-2241N	-	-	crc64:D65745E1FA40C09D	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/03/16	2014/10/16	rogid:PItttC1PU1uY3NT8h7wa9TcuXrU559292	rogid:SpxM+SnEmiw+uQlCEGZSto/zduw559292	intact-crc:017B6DC11AA2C110|rigid:60W1pyzT49Bl8LHSvw/SLoZ8N6U	false	-	necessary binding region:375-430	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)