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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 43359)
+++ go_inferences.obo	(working copy)
@@ -82422,6 +82422,7 @@
 [Term]
 id: GO:1904211 ! membrane protein proteolysis involved in retrograde protein transport, ER to cytosol
 is_a: GO:0033619 {is_inferred="true"} ! membrane protein proteolysis
+is_a: GO:0051603 {is_inferred="true"} ! proteolysis involved in cellular protein catabolic process
 
 [Term]
 id: GO:1904212 ! regulation of iodide transmembrane transport
@@ -82812,18 +82813,18 @@
 
 [Term]
 id: GO:1904292 ! regulation of ERAD pathway
-is_a: GO:0042176 {is_inferred="true"} ! regulation of protein catabolic process
+is_a: GO:0061136 {is_inferred="true"} ! regulation of proteasomal protein catabolic process
 is_a: GO:1905897 {is_inferred="true"} ! regulation of response to endoplasmic reticulum stress
 
 [Term]
 id: GO:1904293 ! negative regulation of ERAD pathway
-is_a: GO:0042177 {is_inferred="true"} ! negative regulation of protein catabolic process
+is_a: GO:1901799 {is_inferred="true"} ! negative regulation of proteasomal protein catabolic process
 is_a: GO:1903573 {is_inferred="true"} ! negative regulation of response to endoplasmic reticulum stress
 is_a: GO:1904292 {is_inferred="true"} ! regulation of ERAD pathway
 
 [Term]
 id: GO:1904294 ! positive regulation of ERAD pathway
-is_a: GO:0045732 {is_inferred="true"} ! positive regulation of protein catabolic process
+is_a: GO:1901800 {is_inferred="true"} ! positive regulation of proteasomal protein catabolic process
 is_a: GO:1904292 {is_inferred="true"} ! regulation of ERAD pathway
 is_a: GO:1905898 {is_inferred="true"} ! positive regulation of response to endoplasmic reticulum stress
 
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 43243)
+++ go_inferences.obo	(working copy)
@@ -11780,17 +11780,17 @@
 is_a: GO:0030163 {is_inferred="true"} ! protein catabolic process
 
 [Term]
-id: GO:0010506 ! regulation of autophagy
+id: GO:0010506 ! regulation of catabolic autophagy
 is_a: GO:0031329 {is_inferred="true"} ! regulation of cellular catabolic process
 
 [Term]
-id: GO:0010507 ! negative regulation of autophagy
-is_a: GO:0010506 {is_inferred="true"} ! regulation of autophagy
+id: GO:0010507 ! negative regulation of catabolic autophagy
+is_a: GO:0010506 {is_inferred="true"} ! regulation of catabolic autophagy
 is_a: GO:0031330 {is_inferred="true"} ! negative regulation of cellular catabolic process
 
 [Term]
-id: GO:0010508 ! positive regulation of autophagy
-is_a: GO:0010506 {is_inferred="true"} ! regulation of autophagy
+id: GO:0010508 ! positive regulation of catabolic autophagy
+is_a: GO:0010506 {is_inferred="true"} ! regulation of catabolic autophagy
 is_a: GO:0031331 {is_inferred="true"} ! positive regulation of cellular catabolic process
 
 [Term]
@@ -16573,7 +16573,7 @@
 
 [Term]
 id: GO:0016239 ! positive regulation of macroautophagy
-is_a: GO:0010508 {is_inferred="true"} ! positive regulation of autophagy
+is_a: GO:0010508 {is_inferred="true"} ! positive regulation of catabolic autophagy
 is_a: GO:0016241 {is_inferred="true"} ! regulation of macroautophagy
 
 [Term]
@@ -16582,11 +16582,11 @@
 
 [Term]
 id: GO:0016241 ! regulation of macroautophagy
-is_a: GO:0010506 {is_inferred="true"} ! regulation of autophagy
+is_a: GO:0010506 {is_inferred="true"} ! regulation of catabolic autophagy
 
 [Term]
 id: GO:0016242 ! negative regulation of macroautophagy
-is_a: GO:0010507 {is_inferred="true"} ! negative regulation of autophagy
+is_a: GO:0010507 {is_inferred="true"} ! negative regulation of catabolic autophagy
 is_a: GO:0016241 {is_inferred="true"} ! regulation of macroautophagy
 
 [Term]
@@ -27800,7 +27800,7 @@
 [Term]
 id: GO:0034263 ! positive regulation of autophagy in response to ER overload
 is_a: GO:0006983 {is_inferred="true"} ! ER overload response
-is_a: GO:0010508 {is_inferred="true"} ! positive regulation of autophagy
+is_a: GO:0010508 {is_inferred="true"} ! positive regulation of catabolic autophagy
 
 [Term]
 id: GO:0034264 ! isopentenyl adenine metabolic process
@@ -55222,7 +55222,7 @@
 
 [Term]
 id: GO:0075071 ! autophagy involved in symbiotic interaction
-is_a: GO:0006914 {is_inferred="true"} ! autophagy
+is_a: GO:0006914 {is_inferred="true"} ! catabolic autophagy
 
 [Term]
 id: GO:0075075 ! modulation by host of symbiont adenylate cyclase activity
@@ -77452,12 +77452,12 @@
 
 [Term]
 id: GO:1903146 ! regulation of mitophagy
-is_a: GO:0010506 {is_inferred="true"} ! regulation of autophagy
+is_a: GO:0010506 {is_inferred="true"} ! regulation of catabolic autophagy
 is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 
 [Term]
 id: GO:1903147 ! negative regulation of mitophagy
-is_a: GO:0010507 {is_inferred="true"} ! negative regulation of autophagy
+is_a: GO:0010507 {is_inferred="true"} ! negative regulation of catabolic autophagy
 is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:1903146 {is_inferred="true"} ! regulation of mitophagy
 
@@ -79535,7 +79535,7 @@
 
 [Term]
 id: GO:1903599 ! positive regulation of mitophagy
-is_a: GO:0010508 {is_inferred="true"} ! positive regulation of autophagy
+is_a: GO:0010508 {is_inferred="true"} ! positive regulation of catabolic autophagy
 is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 is_a: GO:1903146 {is_inferred="true"} ! regulation of mitophagy
 
@@ -81672,13 +81672,13 @@
 
 [Term]
 id: GO:1904051 ! regulation of protein targeting to vacuole involved in autophagy
-is_a: GO:0010506 {is_inferred="true"} ! regulation of autophagy
+is_a: GO:0010506 {is_inferred="true"} ! regulation of catabolic autophagy
 is_a: GO:1903335 {is_inferred="true"} ! regulation of vacuolar transport
 is_a: GO:1903533 {is_inferred="true"} ! regulation of protein targeting
 
 [Term]
 id: GO:1904052 ! negative regulation of protein targeting to vacuole involved in autophagy
-is_a: GO:0010507 {is_inferred="true"} ! negative regulation of autophagy
+is_a: GO:0010507 {is_inferred="true"} ! negative regulation of catabolic autophagy
 is_a: GO:0090317 {is_inferred="true"} ! negative regulation of intracellular protein transport
 is_a: GO:1903336 {is_inferred="true"} ! negative regulation of vacuolar transport
 is_a: GO:1904051 {is_inferred="true"} ! regulation of protein targeting to vacuole involved in autophagy
@@ -81685,7 +81685,7 @@
 
 [Term]
 id: GO:1904053 ! positive regulation of protein targeting to vacuole involved in autophagy
-is_a: GO:0010508 {is_inferred="true"} ! positive regulation of autophagy
+is_a: GO:0010508 {is_inferred="true"} ! positive regulation of catabolic autophagy
 is_a: GO:0090316 {is_inferred="true"} ! positive regulation of intracellular protein transport
 is_a: GO:1903337 {is_inferred="true"} ! positive regulation of vacuolar transport
 is_a: GO:1904051 {is_inferred="true"} ! regulation of protein targeting to vacuole involved in autophagy
@@ -84883,13 +84883,13 @@
 
 [Term]
 id: GO:1904714 ! regulation of chaperone-mediated autophagy
-is_a: GO:0010506 {is_inferred="true"} ! regulation of autophagy
+is_a: GO:0010506 {is_inferred="true"} ! regulation of catabolic autophagy
 is_a: GO:0034248 {is_inferred="true"} ! regulation of cellular amide metabolic process
 is_a: GO:0042176 {is_inferred="true"} ! regulation of protein catabolic process
 
 [Term]
 id: GO:1904715 ! negative regulation of chaperone-mediated autophagy
-is_a: GO:0010507 {is_inferred="true"} ! negative regulation of autophagy
+is_a: GO:0010507 {is_inferred="true"} ! negative regulation of catabolic autophagy
 is_a: GO:0034249 {is_inferred="true"} ! negative regulation of cellular amide metabolic process
 is_a: GO:0042177 {is_inferred="true"} ! negative regulation of protein catabolic process
 is_a: GO:1904714 {is_inferred="true"} ! regulation of chaperone-mediated autophagy
@@ -84896,7 +84896,7 @@
 
 [Term]
 id: GO:1904716 ! positive regulation of chaperone-mediated autophagy
-is_a: GO:0010508 {is_inferred="true"} ! positive regulation of autophagy
+is_a: GO:0010508 {is_inferred="true"} ! positive regulation of catabolic autophagy
 is_a: GO:0034250 {is_inferred="true"} ! positive regulation of cellular amide metabolic process
 is_a: GO:0045732 {is_inferred="true"} ! positive regulation of protein catabolic process
 is_a: GO:1904714 {is_inferred="true"} ! regulation of chaperone-mediated autophagy
@@ -97539,7 +97539,8 @@
 is_a: GO:2001156 {is_inferred="true"} ! regulation of proline catabolic process to glutamate
 
 [Term]
-id: GO:2001159 ! regulation of CVT pathway
+id: GO:2001159 ! regulation of Cvt pathway
+is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
 is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
 
 [Term]
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 43217)
+++ go_inferences.obo	(working copy)
@@ -60896,8 +60896,8 @@
 is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
 
 [Term]
-id: GO:0099614 ! protein targeting to spore cell wall
-is_a: GO:0099613 {is_inferred="true"} ! protein targeting to cell wall
+id: GO:0099614 ! protein localization to spore cell wall
+is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
 
 [Term]
 id: GO:0099616 ! extrinsic component of matrix side of mitochondrial inner membrane
@@ -85571,7 +85571,7 @@
 
 [Term]
 id: GO:1904853 ! protein localization to ascospore wall
-is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
+is_a: GO:0099614 {is_inferred="true"} ! protein localization to spore cell wall
 
 [Term]
 id: GO:1904854 ! proteasome core complex binding
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 43214)
+++ go_inferences.obo	(working copy)
@@ -1424,6 +1424,10 @@
 is_a: GO:0098988 {is_inferred="true"} ! G-protein coupled glutamate receptor activity
 
 [Term]
+id: GO:0001646 ! cAMP receptor activity
+is_a: GO:0004930 {is_inferred="true"} ! G-protein coupled receptor activity
+
+[Term]
 id: GO:0001657 ! ureteric bud development
 is_a: GO:0072164 {is_inferred="true"} ! mesonephric tubule development
 
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 43207)
+++ go_inferences.obo	(working copy)
@@ -8067,6 +8067,11 @@
 is_a: GO:0007088 {is_inferred="true"} ! regulation of mitotic nuclear division
 
 [Term]
+id: GO:0007097 ! nuclear migration
+is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
+is_a: GO:0051656 {is_inferred="true"} ! establishment of organelle localization
+
+[Term]
 id: GO:0007098 ! centrosome cycle
 is_a: GO:0031023 {is_inferred="true"} ! microtubule organizing center organization
 
@@ -8286,7 +8291,7 @@
 [Term]
 id: GO:0007312 ! oocyte nucleus migration involved in oocyte dorsal/ventral axis specification
 is_a: GO:0007097 {is_inferred="true"} ! nuclear migration
-is_a: GO:0022414 {is_inferred="true"} ! reproductive process
+is_a: GO:0051663 {is_inferred="true"} ! oocyte nucleus localization involved in oocyte dorsal/ventral axis specification
 
 [Term]
 id: GO:0007315 ! pole plasm assembly
@@ -21276,6 +21281,7 @@
 
 [Term]
 id: GO:0031022 ! nuclear migration along microfilament
+is_a: GO:0007097 {is_inferred="true"} ! nuclear migration
 is_a: GO:0099515 {is_inferred="true"} ! actin filament-based transport
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
@@ -30798,10 +30804,6 @@
 is_a: GO:0051445 {is_inferred="true"} ! regulation of meiotic cell cycle
 
 [Term]
-id: GO:0040023 ! establishment of nucleus localization
-is_a: GO:0051647 {is_inferred="true"} ! nucleus localization
-
-[Term]
 id: GO:0040026 ! positive regulation of vulval development
 is_a: GO:0040028 {is_inferred="true"} ! regulation of vulval development
 is_a: GO:0061063 {is_inferred="true"} ! positive regulation of nematode larval development
@@ -30892,6 +30894,8 @@
 [Term]
 id: GO:0042070 ! maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis specification
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
+is_a: GO:0051658 {is_inferred="true"} ! maintenance of nucleus location
+is_a: GO:0051663 {is_inferred="true"} ! oocyte nucleus localization involved in oocyte dorsal/ventral axis specification
 
 [Term]
 id: GO:0042073 ! intraciliary transport
@@ -44713,6 +44717,7 @@
 [Term]
 id: GO:0051663 ! oocyte nucleus localization involved in oocyte dorsal/ventral axis specification
 is_a: GO:0022414 {is_inferred="true"} ! reproductive process
+is_a: GO:0051647 {is_inferred="true"} ! nucleus localization
 
 [Term]
 id: GO:0051667 ! establishment of plastid localization
@@ -59590,7 +59595,8 @@
 
 [Term]
 id: GO:0098863 ! nuclear migration by microtubule mediated pushing forces
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
+is_a: GO:0099111 {is_inferred="true"} ! microtubule-based transport
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:0098866 ! multivesicular body fusion to apical plasma membrane
------------------------------------------------------------------------
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changes in entailments

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changes in entailments

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synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 43204)
+++ go_inferences.obo	(working copy)
@@ -33444,10 +33444,6 @@
 is_a: GO:0072666 {is_inferred="true"} ! establishment of protein localization to vacuole
 
 [Term]
-id: GO:0043329 ! protein targeting to membrane involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
-is_a: GO:0006612 {is_inferred="true"} ! protein targeting to membrane
-
-[Term]
 id: GO:0043331 ! response to dsRNA
 is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
 is_a: GO:1901698 {is_inferred="true"} ! response to nitrogen compound
------------------------------------------------------------------------
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changes in entailments

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changes in entailments

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synced

changes in entailments

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synced

changes in entailments

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changes in entailments

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changes in entailments

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synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 43195)
+++ go_inferences.obo	(working copy)
@@ -26255,7 +26255,7 @@
 is_a: GO:0000076 {is_inferred="true"} ! DNA replication checkpoint
 
 [Term]
-id: GO:0033315 ! meiotic DNA replication checkpoint
+id: GO:0033315 ! meiotic G2/MI DNA replication checkpoint
 is_a: GO:0000076 {is_inferred="true"} ! DNA replication checkpoint
 
 [Term]
@@ -35322,6 +35322,7 @@
 id: GO:0045128 ! negative regulation of reciprocal meiotic recombination
 is_a: GO:0010520 {is_inferred="true"} ! regulation of reciprocal meiotic recombination
 is_a: GO:0045910 {is_inferred="true"} ! negative regulation of DNA recombination
+is_a: GO:0110029 {is_inferred="true"} ! negative regulation of meiosis I
 
 [Term]
 id: GO:0045132 ! meiotic chromosome segregation
@@ -61514,6 +61515,31 @@
 is_a: GO:0090068 {is_inferred="true"} ! positive regulation of cell cycle process
 
 [Term]
+id: GO:0110029 ! negative regulation of meiosis I
+is_a: GO:0045835 {is_inferred="true"} ! negative regulation of meiotic nuclear division
+is_a: GO:0060631 {is_inferred="true"} ! regulation of meiosis I
+
+[Term]
+id: GO:0110030 ! regulation of G2/MI transition of meiotic cell cycle
+is_a: GO:0060631 {is_inferred="true"} ! regulation of meiosis I
+is_a: GO:1901993 {is_inferred="true"} ! regulation of meiotic cell cycle phase transition
+is_a: GO:1902749 {is_inferred="true"} ! regulation of cell cycle G2/M phase transition
+
+[Term]
+id: GO:0110031 ! negative regulation of G2/MI transition of meiotic cell cycle
+is_a: GO:0110029 {is_inferred="true"} ! negative regulation of meiosis I
+is_a: GO:0110030 {is_inferred="true"} ! regulation of G2/MI transition of meiotic cell cycle
+is_a: GO:1901994 {is_inferred="true"} ! negative regulation of meiotic cell cycle phase transition
+is_a: GO:1902750 {is_inferred="true"} ! negative regulation of cell cycle G2/M phase transition
+
+[Term]
+id: GO:0110032 ! positive regulation of G2/MI transition of meiotic cell cycle
+is_a: GO:0060903 {is_inferred="true"} ! positive regulation of meiosis I
+is_a: GO:0110030 {is_inferred="true"} ! regulation of G2/MI transition of meiotic cell cycle
+is_a: GO:1901995 {is_inferred="true"} ! positive regulation of meiotic cell cycle phase transition
+is_a: GO:1902751 {is_inferred="true"} ! positive regulation of cell cycle G2/M phase transition
+
+[Term]
 id: GO:0120006 ! regulation of glutamatergic neuron differentiation
 is_a: GO:0045664 {is_inferred="true"} ! regulation of neuron differentiation
 
@@ -78278,8 +78304,8 @@
 [Term]
 id: GO:1903342 ! negative regulation of meiotic DNA double-strand break formation
 is_a: GO:0010605 {is_inferred="true"} ! negative regulation of macromolecule metabolic process
-is_a: GO:0045835 {is_inferred="true"} ! negative regulation of meiotic nuclear division
 is_a: GO:0045934 {is_inferred="true"} ! negative regulation of nucleobase-containing compound metabolic process
+is_a: GO:0110029 {is_inferred="true"} ! negative regulation of meiosis I
 is_a: GO:1903341 {is_inferred="true"} ! regulation of meiotic DNA double-strand break formation
 
 [Term]
@@ -87179,6 +87205,7 @@
 
 [Term]
 id: GO:1905187 ! negative regulation of metaphase/anaphase transition of meiosis I
+is_a: GO:0110029 {is_inferred="true"} ! negative regulation of meiosis I
 is_a: GO:1902103 {is_inferred="true"} ! negative regulation of metaphase/anaphase transition of meiotic cell cycle
 is_a: GO:1905186 {is_inferred="true"} ! regulation of metaphase/anaphase transition of meiosis I
 
------------------------------------------------------------------------
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changes in entailments

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synced

changes in entailments

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synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 43190)
+++ go_inferences.obo	(working copy)
@@ -61425,6 +61425,10 @@
 is_a: GO:0106023 {is_inferred="true"} ! regulation of pupariation
 
 [Term]
+id: GO:0106037 ! apicomedial cortex
+is_a: GO:0045179 {is_inferred="true"} ! apical cortex
+
+[Term]
 id: GO:0110001 ! toxin-antitoxin complex
 is_a: GO:0005667 {is_inferred="true"} ! transcription factor complex
 is_a: GO:0017053 {is_inferred="true"} ! transcriptional repressor complex
------------------------------------------------------------------------
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changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 43189)
+++ go_inferences.obo	(working copy)
@@ -218,6 +218,10 @@
 is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
 
 [Term]
+id: GO:0000054 ! ribosomal subunit export from nucleus
+is_a: GO:0051656 {is_inferred="true"} ! establishment of organelle localization
+
+[Term]
 id: GO:0000055 ! ribosomal large subunit export from nucleus
 is_a: GO:0000054 {is_inferred="true"} ! ribosomal subunit export from nucleus
 
@@ -27065,11 +27069,6 @@
 is_a: GO:0051640 {is_inferred="true"} ! organelle localization
 
 [Term]
-id: GO:0033753 ! establishment of ribosome localization
-is_a: GO:0033750 {is_inferred="true"} ! ribosome localization
-is_a: GO:0045184 {is_inferred="true"} ! establishment of protein localization
-
-[Term]
 id: GO:0033762 ! response to glucagon
 is_a: GO:0043434 {is_inferred="true"} ! response to peptide hormone
 
------------------------------------------------------------------------
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changes in entailments

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synced

changes in entailments

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changes in entailments

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changes in entailments

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changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 43178)
+++ go_inferences.obo	(working copy)
@@ -32818,19 +32818,19 @@
 id: GO:0042996 ! regulation of Golgi to plasma membrane protein transport
 is_a: GO:0051223 {is_inferred="true"} ! regulation of protein transport
 is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
-is_a: GO:0090003 {is_inferred="true"} ! regulation of establishment of protein localization to plasma membrane
+is_a: GO:1903076 {is_inferred="true"} ! regulation of protein localization to plasma membrane
 
 [Term]
 id: GO:0042997 ! negative regulation of Golgi to plasma membrane protein transport
 is_a: GO:0042996 {is_inferred="true"} ! regulation of Golgi to plasma membrane protein transport
 is_a: GO:0051224 {is_inferred="true"} ! negative regulation of protein transport
-is_a: GO:0090005 {is_inferred="true"} ! negative regulation of establishment of protein localization to plasma membrane
+is_a: GO:1903077 {is_inferred="true"} ! negative regulation of protein localization to plasma membrane
 
 [Term]
 id: GO:0042998 ! positive regulation of Golgi to plasma membrane protein transport
 is_a: GO:0042996 {is_inferred="true"} ! regulation of Golgi to plasma membrane protein transport
 is_a: GO:0051222 {is_inferred="true"} ! positive regulation of protein transport
-is_a: GO:0090004 {is_inferred="true"} ! positive regulation of establishment of protein localization to plasma membrane
+is_a: GO:1903078 {is_inferred="true"} ! positive regulation of protein localization to plasma membrane
 
 [Term]
 id: GO:0042999 ! regulation of Golgi to plasma membrane CFTR protein transport
@@ -32841,7 +32841,8 @@
 is_a: GO:0006893 {is_inferred="true"} ! Golgi to plasma membrane transport
 is_a: GO:0015031 {is_inferred="true"} ! protein transport
 is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
-is_a: GO:0090002 {is_inferred="true"} ! establishment of protein localization to plasma membrane
+is_a: GO:0072659 {is_inferred="true"} ! protein localization to plasma membrane
+is_a: GO:0090150 {is_inferred="true"} ! establishment of protein localization to membrane
 
 [Term]
 id: GO:0043002 ! negative regulation of Golgi to plasma membrane CFTR protein transport
@@ -54755,10 +54756,6 @@
 is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
 
 [Term]
-id: GO:0072661 ! protein targeting to plasma membrane
-is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
-
-[Term]
 id: GO:0072662 ! protein localization to peroxisome
 is_a: GO:0033365 {is_inferred="true"} ! protein localization to organelle
 
@@ -54796,10 +54793,6 @@
 is_a: GO:1902974 {is_inferred="true"} ! meiotic DNA replication initiation
 
 [Term]
-id: GO:0072693 ! protein targeting to prospore membrane
-is_a: GO:1902658 {is_inferred="true"} ! establishment of protein localization to prospore membrane
-
-[Term]
 id: GO:0072697 ! protein localization to cell cortex
 is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
 
@@ -56274,27 +56267,6 @@
 is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
-id: GO:0090002 ! establishment of protein localization to plasma membrane
-is_a: GO:0072659 {is_inferred="true"} ! protein localization to plasma membrane
-
-[Term]
-id: GO:0090003 ! regulation of establishment of protein localization to plasma membrane
-is_a: GO:0070201 {is_inferred="true"} ! regulation of establishment of protein localization
-is_a: GO:1903076 {is_inferred="true"} ! regulation of protein localization to plasma membrane
-
-[Term]
-id: GO:0090004 ! positive regulation of establishment of protein localization to plasma membrane
-is_a: GO:0090003 {is_inferred="true"} ! regulation of establishment of protein localization to plasma membrane
-is_a: GO:1903078 {is_inferred="true"} ! positive regulation of protein localization to plasma membrane
-is_a: GO:1904951 {is_inferred="true"} ! positive regulation of establishment of protein localization
-
-[Term]
-id: GO:0090005 ! negative regulation of establishment of protein localization to plasma membrane
-is_a: GO:0090003 {is_inferred="true"} ! regulation of establishment of protein localization to plasma membrane
-is_a: GO:1903077 {is_inferred="true"} ! negative regulation of protein localization to plasma membrane
-is_a: GO:1904950 {is_inferred="true"} ! negative regulation of establishment of protein localization
-
-[Term]
 id: GO:0090006 ! regulation of linear element assembly
 is_a: GO:0033044 {is_inferred="true"} ! regulation of chromosome organization
 is_a: GO:0044087 {is_inferred="true"} ! regulation of cellular component biogenesis
@@ -60979,7 +60951,8 @@
 [Term]
 id: GO:0099638 ! endosome to plasma membrane protein transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
-is_a: GO:0090002 {is_inferred="true"} ! establishment of protein localization to plasma membrane
+is_a: GO:0072659 {is_inferred="true"} ! protein localization to plasma membrane
+is_a: GO:0090150 {is_inferred="true"} ! establishment of protein localization to membrane
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 is_a: GO:1990126 {is_inferred="true"} ! retrograde transport, endosome to plasma membrane
 
@@ -75220,11 +75193,6 @@
 is_a: GO:0072657 {is_inferred="true"} ! protein localization to membrane
 
 [Term]
-id: GO:1902658 ! establishment of protein localization to prospore membrane
-is_a: GO:0090150 {is_inferred="true"} ! establishment of protein localization to membrane
-is_a: GO:1902657 {is_inferred="true"} ! protein localization to prospore membrane
-
-[Term]
 id: GO:1902659 ! regulation of glucose mediated signaling pathway
 is_a: GO:0009966 {is_inferred="true"} ! regulation of signal transduction
 is_a: GO:0032844 {is_inferred="true"} ! regulation of homeostatic process
@@ -78799,6 +78767,10 @@
 is_a: GO:0090335 {is_inferred="true"} ! regulation of brown fat cell differentiation
 
 [Term]
+id: GO:1903445 ! protein transport from ciliary membrane to plasma membrane
+is_a: GO:0090150 {is_inferred="true"} ! establishment of protein localization to membrane
+
+[Term]
 id: GO:1903446 ! geraniol metabolic process
 is_a: GO:0016093 {is_inferred="true"} ! polyprenol metabolic process
 is_a: GO:0016098 {is_inferred="true"} ! monoterpenoid metabolic process
@@ -89804,18 +89776,18 @@
 id: GO:1905749 ! regulation of endosome to plasma membrane protein transport
 is_a: GO:0033157 {is_inferred="true"} ! regulation of intracellular protein transport
 is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
-is_a: GO:0090003 {is_inferred="true"} ! regulation of establishment of protein localization to plasma membrane
+is_a: GO:1903076 {is_inferred="true"} ! regulation of protein localization to plasma membrane
 
 [Term]
 id: GO:1905750 ! negative regulation of endosome to plasma membrane protein transport
-is_a: GO:0090005 {is_inferred="true"} ! negative regulation of establishment of protein localization to plasma membrane
 is_a: GO:0090317 {is_inferred="true"} ! negative regulation of intracellular protein transport
+is_a: GO:1903077 {is_inferred="true"} ! negative regulation of protein localization to plasma membrane
 is_a: GO:1905749 {is_inferred="true"} ! regulation of endosome to plasma membrane protein transport
 
 [Term]
 id: GO:1905751 ! positive regulation of endosome to plasma membrane protein transport
-is_a: GO:0090004 {is_inferred="true"} ! positive regulation of establishment of protein localization to plasma membrane
 is_a: GO:0090316 {is_inferred="true"} ! positive regulation of intracellular protein transport
+is_a: GO:1903078 {is_inferred="true"} ! positive regulation of protein localization to plasma membrane
 is_a: GO:1905749 {is_inferred="true"} ! regulation of endosome to plasma membrane protein transport
 
 [Term]
@@ -90917,23 +90889,6 @@
 is_a: GO:0030182 {is_inferred="true"} ! neuron differentiation
 
 [Term]
-id: GO:1905963 ! regulation of protein targeting to plasma membrane
-is_a: GO:0090003 {is_inferred="true"} ! regulation of establishment of protein localization to plasma membrane
-is_a: GO:0090313 {is_inferred="true"} ! regulation of protein targeting to membrane
-
-[Term]
-id: GO:1905964 ! negative regulation of protein targeting to plasma membrane
-is_a: GO:0090005 {is_inferred="true"} ! negative regulation of establishment of protein localization to plasma membrane
-is_a: GO:0090315 {is_inferred="true"} ! negative regulation of protein targeting to membrane
-is_a: GO:1905963 {is_inferred="true"} ! regulation of protein targeting to plasma membrane
-
-[Term]
-id: GO:1905965 ! positive regulation of protein targeting to plasma membrane
-is_a: GO:0090004 {is_inferred="true"} ! positive regulation of establishment of protein localization to plasma membrane
-is_a: GO:0090314 {is_inferred="true"} ! positive regulation of protein targeting to membrane
-is_a: GO:1905963 {is_inferred="true"} ! regulation of protein targeting to plasma membrane
-
-[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
@@ -97905,15 +97860,10 @@
 is_a: GO:2001228 {is_inferred="true"} ! regulation of response to gamma radiation
 
 [Term]
-id: GO:2001231 ! regulation of protein targeting to prospore membrane
-is_a: GO:0090313 {is_inferred="true"} ! regulation of protein targeting to membrane
+id: GO:2001232 ! positive regulation of protein localization to prospore membrane
+is_a: GO:2001231 {is_inferred="true"} ! regulation of protein localization to prospore membrane
 
 [Term]
-id: GO:2001232 ! positive regulation of protein targeting to prospore membrane
-is_a: GO:0090314 {is_inferred="true"} ! positive regulation of protein targeting to membrane
-is_a: GO:2001231 {is_inferred="true"} ! regulation of protein targeting to prospore membrane
-
-[Term]
 id: GO:2001233 ! regulation of apoptotic signaling pathway
 is_a: GO:0009966 {is_inferred="true"} ! regulation of signal transduction
 is_a: GO:0042981 {is_inferred="true"} ! regulation of apoptotic process
------------------------------------------------------------------------
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synced

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synced

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synced

changes in entailments

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synced

changes in entailments

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synced

changes in entailments

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synced

changes in entailments

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synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 43166)
+++ go_inferences.obo	(working copy)
@@ -91654,7 +91654,6 @@
 
 [Term]
 id: GO:1990621 ! ESCRT IV complex
-is_a: GO:0044440 {is_inferred="true"} ! endosomal part
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 is_a: GO:1904949 {is_inferred="true"} ! ATPase complex
 
------------------------------------------------------------------------
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synced

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synced

changes in entailments

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synced

changes in entailments

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synced

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synced

changes in entailments

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synced

changes in entailments

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synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 43148)
+++ go_inferences.obo	(working copy)
@@ -8280,6 +8280,11 @@
 is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
+id: GO:0007312 ! oocyte nucleus migration involved in oocyte dorsal/ventral axis specification
+is_a: GO:0007097 {is_inferred="true"} ! nuclear migration
+is_a: GO:0022414 {is_inferred="true"} ! reproductive process
+
+[Term]
 id: GO:0007315 ! pole plasm assembly
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
@@ -20739,11 +20744,6 @@
 is_a: GO:0006996 {is_inferred="true"} ! organelle organization
 
 [Term]
-id: GO:0030722 ! establishment of oocyte nucleus localization involved in oocyte dorsal/ventral axis specification
-is_a: GO:0022414 {is_inferred="true"} ! reproductive process
-is_a: GO:0040023 {is_inferred="true"} ! establishment of nucleus localization
-
-[Term]
 id: GO:0030725 ! germline ring canal formation
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 43147)
+++ go_inferences.obo	(working copy)
@@ -42833,6 +42833,10 @@
 is_a: GO:0050857 {is_inferred="true"} ! positive regulation of antigen receptor-mediated signaling pathway
 
 [Term]
+id: GO:0050877 ! nervous system process
+is_a: GO:0003008 {is_inferred="true"} ! system process
+
+[Term]
 id: GO:0050897 ! cobalt ion binding
 is_a: GO:0046914 {is_inferred="true"} ! transition metal ion binding
 
------------------------------------------------------------------------
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changes in entailments

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changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 43133)
+++ go_inferences.obo	(working copy)
@@ -49509,6 +49509,15 @@
 is_a: GO:0051641 {is_inferred="true"} ! cellular localization
 
 [Term]
+id: GO:0061916 ! leading edge of axonal growth cone
+is_a: GO:0033267 {is_inferred="true"} ! axon part
+is_a: GO:0061850 {is_inferred="true"} ! growth cone leading edge
+
+[Term]
+id: GO:0061917 ! leading edge of dendritic growth cone
+is_a: GO:0061850 {is_inferred="true"} ! growth cone leading edge
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
------------------------------------------------------------------------
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synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 43132)
+++ go_inferences.obo	(working copy)
@@ -49505,6 +49505,10 @@
 is_a: GO:1903011 {is_inferred="true"} ! negative regulation of bone development
 
 [Term]
+id: GO:0061915 ! actin fusion focus localization
+is_a: GO:0051641 {is_inferred="true"} ! cellular localization
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
------------------------------------------------------------------------
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synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 43131)
+++ go_inferences.obo	(working copy)
@@ -49489,6 +49489,22 @@
 is_a: GO:2001258 {is_inferred="true"} ! negative regulation of cation channel activity
 
 [Term]
+id: GO:0061913 ! positive regulation of growth plate cartilage chondrocyte proliferation
+is_a: GO:0003420 {is_inferred="true"} ! regulation of growth plate cartilage chondrocyte proliferation
+is_a: GO:0008284 {is_inferred="true"} ! positive regulation of cell proliferation
+is_a: GO:0046622 {is_inferred="true"} ! positive regulation of organ growth
+is_a: GO:0061036 {is_inferred="true"} ! positive regulation of cartilage development
+is_a: GO:1903012 {is_inferred="true"} ! positive regulation of bone development
+
+[Term]
+id: GO:0061914 ! negative regulation of growth plate cartilage chondrocyte proliferation
+is_a: GO:0003420 {is_inferred="true"} ! regulation of growth plate cartilage chondrocyte proliferation
+is_a: GO:0008285 {is_inferred="true"} ! negative regulation of cell proliferation
+is_a: GO:0046621 {is_inferred="true"} ! negative regulation of organ growth
+is_a: GO:0061037 {is_inferred="true"} ! negative regulation of cartilage development
+is_a: GO:1903011 {is_inferred="true"} ! negative regulation of bone development
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
------------------------------------------------------------------------
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changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 43127)
+++ go_inferences.obo	(working copy)
@@ -714,20 +714,22 @@
 is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
 
 [Term]
-id: GO:0000423 ! macromitophagy
+id: GO:0000423 ! mitophagy
 is_a: GO:0000422 {is_inferred="true"} ! autophagy of mitochondrion
+is_a: GO:0061912 {is_inferred="true"} ! selective autophagy
 
 [Term]
-id: GO:0000424 ! microautophagy of mitochondrion
+id: GO:0000424 ! micromitophagy
 is_a: GO:0000422 {is_inferred="true"} ! autophagy of mitochondrion
 
 [Term]
-id: GO:0000425 ! macropexophagy
-is_a: GO:0030242 {is_inferred="true"} ! pexophagy
+id: GO:0000425 ! pexophagy
+is_a: GO:0030242 {is_inferred="true"} ! autophagy of peroxisome
+is_a: GO:0061912 {is_inferred="true"} ! selective autophagy
 
 [Term]
 id: GO:0000426 ! micropexophagy
-is_a: GO:0030242 {is_inferred="true"} ! pexophagy
+is_a: GO:0030242 {is_inferred="true"} ! autophagy of peroxisome
 
 [Term]
 id: GO:0000427 ! plastid-encoded plastid RNA polymerase complex
@@ -28184,6 +28186,10 @@
 is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
 
 [Term]
+id: GO:0034517 ! ribophagy
+is_a: GO:0061912 {is_inferred="true"} ! selective autophagy
+
+[Term]
 id: GO:0034518 ! RNA cap binding complex
 is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
 
@@ -28400,7 +28406,7 @@
 
 [Term]
 id: GO:0034727 ! piecemeal microautophagy of nucleus
-is_a: GO:0044804 {is_inferred="true"} ! nucleophagy
+is_a: GO:0044804 {is_inferred="true"} ! autophagy of nucleus
 
 [Term]
 id: GO:0034728 ! nucleosome organization
@@ -29947,6 +29953,10 @@
 is_a: GO:2000911 {is_inferred="true"} ! positive regulation of sterol import
 
 [Term]
+id: GO:0035973 ! aggrephagy
+is_a: GO:0061912 {is_inferred="true"} ! selective autophagy
+
+[Term]
 id: GO:0035975 ! carbamoyl phosphate catabolic process
 is_a: GO:0046434 {is_inferred="true"} ! organophosphate catabolic process
 is_a: GO:0070408 {is_inferred="true"} ! carbamoyl phosphate metabolic process
@@ -49154,6 +49164,7 @@
 [Term]
 id: GO:0061709 ! reticulophagy
 is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
+is_a: GO:0061912 {is_inferred="true"} ! selective autophagy
 
 [Term]
 id: GO:0061716 ! miRNA export from nucleus
@@ -49192,8 +49203,13 @@
 [Term]
 id: GO:0061723 ! glycophagy
 is_a: GO:0005980 {is_inferred="true"} ! glycogen catabolic process
+is_a: GO:0061912 {is_inferred="true"} ! selective autophagy
 
 [Term]
+id: GO:0061724 ! lipophagy
+is_a: GO:0061912 {is_inferred="true"} ! selective autophagy
+
+[Term]
 id: GO:0061727 ! methylglyoxal catabolic process to lactate
 is_a: GO:0006089 {is_inferred="true"} ! lactate metabolic process
 
@@ -83809,18 +83825,15 @@
 [Term]
 id: GO:1904502 ! regulation of lipophagy
 is_a: GO:0016241 {is_inferred="true"} ! regulation of macroautophagy
-is_a: GO:0050994 {is_inferred="true"} ! regulation of lipid catabolic process
 
 [Term]
 id: GO:1904503 ! negative regulation of lipophagy
 is_a: GO:0016242 {is_inferred="true"} ! negative regulation of macroautophagy
-is_a: GO:0050995 {is_inferred="true"} ! negative regulation of lipid catabolic process
 is_a: GO:1904502 {is_inferred="true"} ! regulation of lipophagy
 
 [Term]
 id: GO:1904504 ! positive regulation of lipophagy
 is_a: GO:0016239 {is_inferred="true"} ! positive regulation of macroautophagy
-is_a: GO:0050996 {is_inferred="true"} ! positive regulation of lipid catabolic process
 is_a: GO:1904502 {is_inferred="true"} ! regulation of lipophagy
 
 [Term]
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 43125)
+++ go_inferences.obo	(working copy)
@@ -60586,6 +60586,15 @@
 is_a: GO:1904889 {is_inferred="true"} ! regulation of excitatory synapse assembly
 
 [Term]
+id: GO:0099156 ! cell-cell signaling via exosome
+is_a: GO:0007267 {is_inferred="true"} ! cell-cell signaling
+
+[Term]
+id: GO:0099157 ! transynaptic signalling via exosome
+is_a: GO:0099156 {is_inferred="true"} ! cell-cell signaling via exosome
+is_a: GO:0099537 {is_inferred="true"} ! trans-synaptic signaling
+
+[Term]
 id: GO:0099240 ! intrinsic component of synaptic membrane
 is_a: GO:0031226 {is_inferred="true"} ! intrinsic component of plasma membrane
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
------------------------------------------------------------------------
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synced

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synced

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 43038)
+++ go_inferences.obo	(working copy)
@@ -61716,6 +61716,10 @@
 is_a: GO:0120079 {is_inferred="true"} ! regulation of microfilament motor activity
 
 [Term]
+id: GO:0120085 ! transposon integration involved in RNA-mediated transposition
+is_a: GO:0070893 {is_inferred="true"} ! transposon integration
+
+[Term]
 id: GO:0140009 ! L-aspartate import across plasma membrane
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 is_a: GO:0089712 {is_inferred="true"} ! L-aspartate transmembrane transport
------------------------------------------------------------------------
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synced

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synced

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synced

changes in entailments

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synced

changes in entailments

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synced

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synced

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synced

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synced

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synced

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synced

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 43001)
+++ go_inferences.obo	(working copy)
@@ -61473,6 +61473,13 @@
 is_a: GO:2000104 {is_inferred="true"} ! negative regulation of DNA-dependent DNA replication
 
 [Term]
+id: GO:0110028 ! positive regulation of mitotic spindle organization
+is_a: GO:0045931 {is_inferred="true"} ! positive regulation of mitotic cell cycle
+is_a: GO:0051495 {is_inferred="true"} ! positive regulation of cytoskeleton organization
+is_a: GO:0060236 {is_inferred="true"} ! regulation of mitotic spindle organization
+is_a: GO:0090068 {is_inferred="true"} ! positive regulation of cell cycle process
+
+[Term]
 id: GO:0120006 ! regulation of glutamatergic neuron differentiation
 is_a: GO:0045664 {is_inferred="true"} ! regulation of neuron differentiation
 
@@ -75999,8 +76006,8 @@
 id: GO:1902846 ! positive regulation of mitotic spindle elongation
 is_a: GO:0032888 {is_inferred="true"} ! regulation of mitotic spindle elongation
 is_a: GO:0045840 {is_inferred="true"} ! positive regulation of mitotic nuclear division
-is_a: GO:0051495 {is_inferred="true"} ! positive regulation of cytoskeleton organization
 is_a: GO:0051984 {is_inferred="true"} ! positive regulation of chromosome segregation
+is_a: GO:0110028 {is_inferred="true"} ! positive regulation of mitotic spindle organization
 is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
 
 [Term]
@@ -84681,9 +84688,7 @@
 
 [Term]
 id: GO:1904687 ! positive regulation of mitotic spindle disassembly
-is_a: GO:0045931 {is_inferred="true"} ! positive regulation of mitotic cell cycle
-is_a: GO:0051495 {is_inferred="true"} ! positive regulation of cytoskeleton organization
-is_a: GO:0090068 {is_inferred="true"} ! positive regulation of cell cycle process
+is_a: GO:0110028 {is_inferred="true"} ! positive regulation of mitotic spindle organization
 is_a: GO:1904686 {is_inferred="true"} ! regulation of mitotic spindle disassembly
 
 [Term]
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42979)
+++ go_inferences.obo	(working copy)
@@ -59109,6 +59109,10 @@
 is_a: GO:0050792 {is_inferred="true"} ! regulation of viral process
 
 [Term]
+id: GO:0098692 ! noradrenergic synapse
+is_a: GO:0045202 {is_inferred="true"} ! synapse
+
+[Term]
 id: GO:0098693 ! regulation of synaptic vesicle cycle
 is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
 is_a: GO:0060341 {is_inferred="true"} ! regulation of cellular localization
@@ -61691,6 +61695,20 @@
 is_a: GO:1905208 {is_inferred="true"} ! negative regulation of cardiocyte differentiation
 
 [Term]
+id: GO:0120079 ! regulation of microfilament motor activity
+is_a: GO:0051336 {is_inferred="true"} ! regulation of hydrolase activity
+
+[Term]
+id: GO:0120080 ! negative regulation of microfilament motor activity
+is_a: GO:0051346 {is_inferred="true"} ! negative regulation of hydrolase activity
+is_a: GO:0120079 {is_inferred="true"} ! regulation of microfilament motor activity
+
+[Term]
+id: GO:0120081 ! positive regulation of microfilament motor activity
+is_a: GO:0051345 {is_inferred="true"} ! positive regulation of hydrolase activity
+is_a: GO:0120079 {is_inferred="true"} ! regulation of microfilament motor activity
+
+[Term]
 id: GO:0140009 ! L-aspartate import across plasma membrane
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 is_a: GO:0089712 {is_inferred="true"} ! L-aspartate transmembrane transport
@@ -81849,16 +81867,16 @@
 
 [Term]
 id: GO:1904110 ! regulation of plus-end directed microfilament motor activity
-is_a: GO:0051336 {is_inferred="true"} ! regulation of hydrolase activity
+is_a: GO:0120079 {is_inferred="true"} ! regulation of microfilament motor activity
 
 [Term]
 id: GO:1904111 ! negative regulation of plus-end directed microfilament motor activity
-is_a: GO:0051346 {is_inferred="true"} ! negative regulation of hydrolase activity
+is_a: GO:0120080 {is_inferred="true"} ! negative regulation of microfilament motor activity
 is_a: GO:1904110 {is_inferred="true"} ! regulation of plus-end directed microfilament motor activity
 
 [Term]
 id: GO:1904112 ! positive regulation of plus-end directed microfilament motor activity
-is_a: GO:0051345 {is_inferred="true"} ! positive regulation of hydrolase activity
+is_a: GO:0120081 {is_inferred="true"} ! positive regulation of microfilament motor activity
 is_a: GO:1904110 {is_inferred="true"} ! regulation of plus-end directed microfilament motor activity
 
 [Term]
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42977)
+++ go_inferences.obo	(working copy)
@@ -61460,6 +61460,15 @@
 is_a: GO:2000288 {is_inferred="true"} ! positive regulation of myoblast proliferation
 
 [Term]
+id: GO:0110026 ! regulation of DNA strand resection involved in replication fork processing
+is_a: GO:0090329 {is_inferred="true"} ! regulation of DNA-dependent DNA replication
+
+[Term]
+id: GO:0110027 ! negative regulation of DNA strand resection involved in replication fork processing
+is_a: GO:0110026 {is_inferred="true"} ! regulation of DNA strand resection involved in replication fork processing
+is_a: GO:2000104 {is_inferred="true"} ! negative regulation of DNA-dependent DNA replication
+
+[Term]
 id: GO:0120006 ! regulation of glutamatergic neuron differentiation
 is_a: GO:0045664 {is_inferred="true"} ! regulation of neuron differentiation
 
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42976)
+++ go_inferences.obo	(working copy)
@@ -16960,6 +16960,7 @@
 
 [Term]
 id: GO:0018873 ! atrazine metabolic process
+is_a: GO:0006595 {is_inferred="true"} ! polyamine metabolic process
 is_a: GO:0018965 {is_inferred="true"} ! s-triazine compound metabolic process
 
 [Term]
@@ -18030,6 +18031,7 @@
 
 [Term]
 id: GO:0019381 ! atrazine catabolic process
+is_a: GO:0006598 {is_inferred="true"} ! polyamine catabolic process
 is_a: GO:0018873 {is_inferred="true"} ! atrazine metabolic process
 is_a: GO:0042204 {is_inferred="true"} ! s-triazine compound catabolic process
 
@@ -18910,7 +18912,6 @@
 
 [Term]
 id: GO:0019624 ! atrazine catabolic process to isopropylamine
-is_a: GO:0009308 {is_inferred="true"} ! amine metabolic process
 is_a: GO:0019381 {is_inferred="true"} ! atrazine catabolic process
 is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 is_a: GO:1901160 {is_inferred="true"} ! primary amino compound metabolic process
@@ -67295,18 +67296,18 @@
 
 [Term]
 id: GO:1901055 ! trimethylenediamine metabolic process
+is_a: GO:0006595 {is_inferred="true"} ! polyamine metabolic process
 is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
 
 [Term]
 id: GO:1901056 ! trimethylenediamine catabolic process
+is_a: GO:0006598 {is_inferred="true"} ! polyamine catabolic process
 is_a: GO:1901055 {is_inferred="true"} ! trimethylenediamine metabolic process
-is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
 
 [Term]
 id: GO:1901057 ! trimethylenediamine biosynthetic process
+is_a: GO:0006596 {is_inferred="true"} ! polyamine biosynthetic process
 is_a: GO:1901055 {is_inferred="true"} ! trimethylenediamine metabolic process
-is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
 
 [Term]
 id: GO:1901058 ! p-hydroxyphenyl lignin metabolic process
@@ -79441,17 +79442,17 @@
 
 [Term]
 id: GO:1903601 ! thermospermine metabolic process
+is_a: GO:0006595 {is_inferred="true"} ! polyamine metabolic process
 is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
 
 [Term]
 id: GO:1903602 ! thermospermine catabolic process
-is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
+is_a: GO:0006598 {is_inferred="true"} ! polyamine catabolic process
 is_a: GO:1903601 {is_inferred="true"} ! thermospermine metabolic process
 
 [Term]
 id: GO:1903603 ! thermospermine biosynthetic process
-is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
+is_a: GO:0006596 {is_inferred="true"} ! polyamine biosynthetic process
 is_a: GO:1903601 {is_inferred="true"} ! thermospermine metabolic process
 
 [Term]
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42970)
+++ go_inferences.obo	(working copy)
@@ -60168,6 +60168,7 @@
 [Term]
 id: GO:0099031 ! anchored component of postsynaptic density membrane
 is_a: GO:0099030 {is_inferred="true"} ! anchored component of postsynaptic specialization membrane
+is_a: GO:0099146 {is_inferred="true"} ! intrinsic component of postsynaptic density membrane
 
 [Term]
 id: GO:0099032 ! anchored component of postsynaptic early endosome membrane
@@ -60271,6 +60272,7 @@
 [Term]
 id: GO:0099061 ! integral component of postsynaptic density membrane
 is_a: GO:0099060 {is_inferred="true"} ! integral component of postsynaptic specialization membrane
+is_a: GO:0099146 {is_inferred="true"} ! intrinsic component of postsynaptic density membrane
 
 [Term]
 id: GO:0099062 ! integral component of postsynaptic early endosome membrane
@@ -60550,6 +60552,35 @@
 is_a: GO:1905475 {is_inferred="true"} ! regulation of protein localization to membrane
 
 [Term]
+id: GO:0099146 ! intrinsic component of postsynaptic density membrane
+is_a: GO:0098948 {is_inferred="true"} ! intrinsic component of postsynaptic specialization membrane
+
+[Term]
+id: GO:0099147 ! extrinsic component of postsynaptic density membrane
+is_a: GO:0098892 {is_inferred="true"} ! extrinsic component of postsynaptic specialization membrane
+
+[Term]
+id: GO:0099148 ! regulation of synaptic vesicle docking
+is_a: GO:0106020 {is_inferred="true"} ! regulation of vesicle docking
+is_a: GO:2000300 {is_inferred="true"} ! regulation of synaptic vesicle exocytosis
+
+[Term]
+id: GO:0099149 ! regulation of postsynaptic neurotransmitter receptor internalization
+is_a: GO:0002090 {is_inferred="true"} ! regulation of receptor internalization
+is_a: GO:0060341 {is_inferred="true"} ! regulation of cellular localization
+is_a: GO:0065008 {is_inferred="true"} ! regulation of biological quality
+
+[Term]
+id: GO:0099150 ! regulation of postsynaptic specialization assembly
+is_a: GO:0051963 {is_inferred="true"} ! regulation of synapse assembly
+is_a: GO:1902115 {is_inferred="true"} ! regulation of organelle assembly
+
+[Term]
+id: GO:0099151 ! regulation of postsynaptic density assembly
+is_a: GO:0099150 {is_inferred="true"} ! regulation of postsynaptic specialization assembly
+is_a: GO:1904889 {is_inferred="true"} ! regulation of excitatory synapse assembly
+
+[Term]
 id: GO:0099240 ! intrinsic component of synaptic membrane
 is_a: GO:0031226 {is_inferred="true"} ! intrinsic component of plasma membrane
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42958)
+++ go_inferences.obo	(working copy)
@@ -91384,6 +91384,7 @@
 is_a: GO:0072530 {is_inferred="true"} ! purine-containing compound transmembrane transport
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 is_a: GO:1901679 {is_inferred="true"} ! nucleotide transmembrane transport
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:1990545 ! mitochondrial thiamine pyrophosphate transmembrane transport
------------------------------------------------------------------------
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synced

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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42846)
+++ go_inferences.obo	(working copy)
@@ -1812,10 +1812,6 @@
 is_a: GO:0048646 {is_inferred="true"} ! anatomical structure formation involved in morphogenesis
 
 [Term]
-id: GO:0001948 ! glycoprotein binding
-is_a: GO:0097367 {is_inferred="true"} ! carbohydrate derivative binding
-
-[Term]
 id: GO:0001952 ! regulation of cell-matrix adhesion
 is_a: GO:0010810 {is_inferred="true"} ! regulation of cell-substrate adhesion
 
@@ -33543,7 +33539,8 @@
 
 [Term]
 id: GO:0043394 ! proteoglycan binding
-is_a: GO:0001948 {is_inferred="true"} ! glycoprotein binding
+is_a: GO:0005515 {is_inferred="true"} ! protein binding
+is_a: GO:0097367 {is_inferred="true"} ! carbohydrate derivative binding
 
 [Term]
 id: GO:0043395 ! heparan sulfate proteoglycan binding
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42832)
+++ go_inferences.obo	(working copy)
@@ -61094,6 +61094,11 @@
 is_a: GO:0100024 {is_inferred="true"} ! regulation of carbohydrate metabolic process by transcription from RNA polymerase II promoter
 
 [Term]
+id: GO:0100035 ! negative regulation of transmembrane transport by transcription from RNA polymerase II promoter
+is_a: GO:0034763 {is_inferred="true"} ! negative regulation of transmembrane transport
+is_a: GO:0100020 {is_inferred="true"} ! regulation of transport by transcription from RNA polymerase II promoter
+
+[Term]
 id: GO:0100036 ! positive regulation of purine nucleotide biosynthetic process by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
 is_a: GO:1900373 {is_inferred="true"} ! positive regulation of purine nucleotide biosynthetic process
@@ -63756,7 +63761,9 @@
 
 [Term]
 id: GO:1900417 ! negative regulation of transmembrane transport by negative regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0034763 {is_inferred="true"} ! negative regulation of transmembrane transport
+is_a: GO:0034764 {is_inferred="true"} ! positive regulation of transmembrane transport
+is_a: GO:1900392 {is_inferred="true"} ! regulation of transport by negative regulation of transcription from RNA polymerase II promoter
 
 [Term]
 id: GO:1900418 ! positive regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter
------------------------------------------------------------------------
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synced

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synced

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synced

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synced

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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42823)
+++ go_inferences.obo	(working copy)
@@ -61094,11 +61094,6 @@
 is_a: GO:0100024 {is_inferred="true"} ! regulation of carbohydrate metabolic process by transcription from RNA polymerase II promoter
 
 [Term]
-id: GO:0100035 ! negative regulation of transmembrane transport by transcription from RNA polymerase II promoter
-is_a: GO:0034763 {is_inferred="true"} ! negative regulation of transmembrane transport
-is_a: GO:0100020 {is_inferred="true"} ! regulation of transport by transcription from RNA polymerase II promoter
-
-[Term]
 id: GO:0100036 ! positive regulation of purine nucleotide biosynthetic process by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
 is_a: GO:1900373 {is_inferred="true"} ! positive regulation of purine nucleotide biosynthetic process
@@ -63761,9 +63756,7 @@
 
 [Term]
 id: GO:1900417 ! negative regulation of transmembrane transport by negative regulation of transcription from RNA polymerase II promoter
-is_a: GO:0034763 {is_inferred="true"} ! negative regulation of transmembrane transport
-is_a: GO:0034764 {is_inferred="true"} ! positive regulation of transmembrane transport
-is_a: GO:1900392 {is_inferred="true"} ! regulation of transport by negative regulation of transcription from RNA polymerase II promoter
+is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
 
 [Term]
 id: GO:1900418 ! positive regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42777)
+++ go_inferences.obo	(working copy)
@@ -13447,9 +13447,8 @@
 is_a: GO:0031333 {is_inferred="true"} ! negative regulation of protein complex assembly
 
 [Term]
-id: GO:0010993 ! regulation of ubiquitin homeostasis
-is_a: GO:0032844 {is_inferred="true"} ! regulation of homeostatic process
-is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
+id: GO:0010992 ! ubiquitin recycling
+is_a: GO:0019725 {is_inferred="true"} ! cellular homeostasis
 
 [Term]
 id: GO:0010999 ! regulation of eIF2 alpha phosphorylation by heme
@@ -83926,17 +83925,19 @@
 
 [Term]
 id: GO:1904542 ! regulation of free ubiquitin chain polymerization
-is_a: GO:0010993 {is_inferred="true"} ! regulation of ubiquitin homeostasis
 is_a: GO:0032271 {is_inferred="true"} ! regulation of protein polymerization
+is_a: GO:0032844 {is_inferred="true"} ! regulation of homeostatic process
 
 [Term]
 id: GO:1904543 ! negative regulation of free ubiquitin chain polymerization
 is_a: GO:0032272 {is_inferred="true"} ! negative regulation of protein polymerization
+is_a: GO:0032845 {is_inferred="true"} ! negative regulation of homeostatic process
 is_a: GO:1904542 {is_inferred="true"} ! regulation of free ubiquitin chain polymerization
 
 [Term]
 id: GO:1904544 ! positive regulation of free ubiquitin chain polymerization
 is_a: GO:0032273 {is_inferred="true"} ! positive regulation of protein polymerization
+is_a: GO:0032846 {is_inferred="true"} ! positive regulation of homeostatic process
 is_a: GO:1904542 {is_inferred="true"} ! regulation of free ubiquitin chain polymerization
 
 [Term]
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42723)
+++ go_inferences.obo	(working copy)
@@ -710,16 +710,16 @@
 is_a: GO:0031062 {is_inferred="true"} ! positive regulation of histone methylation
 
 [Term]
-id: GO:0000422 ! mitophagy
+id: GO:0000422 ! autophagy of mitochondrion
 is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
 
 [Term]
 id: GO:0000423 ! macromitophagy
-is_a: GO:0000422 {is_inferred="true"} ! mitophagy
+is_a: GO:0000422 {is_inferred="true"} ! autophagy of mitochondrion
 
 [Term]
 id: GO:0000424 ! microautophagy of mitochondrion
-is_a: GO:0000422 {is_inferred="true"} ! mitophagy
+is_a: GO:0000422 {is_inferred="true"} ! autophagy of mitochondrion
 
 [Term]
 id: GO:0000425 ! macropexophagy
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42711)
+++ go_inferences.obo	(working copy)
@@ -23205,7 +23205,7 @@
 
 [Term]
 id: GO:0032222 ! regulation of synaptic transmission, cholinergic
-is_a: GO:0050804 {is_inferred="true"} ! modulation of synaptic transmission
+is_a: GO:0050804 {is_inferred="true"} ! modulation of chemical synaptic transmission
 
 [Term]
 id: GO:0032223 ! negative regulation of synaptic transmission, cholinergic
@@ -23219,7 +23219,7 @@
 
 [Term]
 id: GO:0032225 ! regulation of synaptic transmission, dopaminergic
-is_a: GO:0050804 {is_inferred="true"} ! modulation of synaptic transmission
+is_a: GO:0050804 {is_inferred="true"} ! modulation of chemical synaptic transmission
 
 [Term]
 id: GO:0032226 ! positive regulation of synaptic transmission, dopaminergic
@@ -23233,7 +23233,7 @@
 
 [Term]
 id: GO:0032228 ! regulation of synaptic transmission, GABAergic
-is_a: GO:0050804 {is_inferred="true"} ! modulation of synaptic transmission
+is_a: GO:0050804 {is_inferred="true"} ! modulation of chemical synaptic transmission
 
 [Term]
 id: GO:0032229 ! negative regulation of synaptic transmission, GABAergic
@@ -40778,7 +40778,7 @@
 [Term]
 id: GO:0046928 ! regulation of neurotransmitter secretion
 is_a: GO:0001505 {is_inferred="true"} ! regulation of neurotransmitter levels
-is_a: GO:0050804 {is_inferred="true"} ! modulation of synaptic transmission
+is_a: GO:0050804 {is_inferred="true"} ! modulation of chemical synaptic transmission
 is_a: GO:0051588 {is_inferred="true"} ! regulation of neurotransmitter transport
 is_a: GO:0060341 {is_inferred="true"} ! regulation of cellular localization
 is_a: GO:1903530 {is_inferred="true"} ! regulation of secretion by cell
@@ -42690,7 +42690,7 @@
 is_a: GO:0050783 {is_inferred="true"} ! cocaine metabolic process
 
 [Term]
-id: GO:0050804 ! modulation of synaptic transmission
+id: GO:0050804 ! modulation of chemical synaptic transmission
 is_a: GO:0010646 {is_inferred="true"} ! regulation of cell communication
 is_a: GO:0023051 {is_inferred="true"} ! regulation of signaling
 
@@ -42698,13 +42698,13 @@
 id: GO:0050805 ! negative regulation of synaptic transmission
 is_a: GO:0010648 {is_inferred="true"} ! negative regulation of cell communication
 is_a: GO:0023057 {is_inferred="true"} ! negative regulation of signaling
-is_a: GO:0050804 {is_inferred="true"} ! modulation of synaptic transmission
+is_a: GO:0050804 {is_inferred="true"} ! modulation of chemical synaptic transmission
 
 [Term]
 id: GO:0050806 ! positive regulation of synaptic transmission
 is_a: GO:0010647 {is_inferred="true"} ! positive regulation of cell communication
 is_a: GO:0023056 {is_inferred="true"} ! positive regulation of signaling
-is_a: GO:0050804 {is_inferred="true"} ! modulation of synaptic transmission
+is_a: GO:0050804 {is_inferred="true"} ! modulation of chemical synaptic transmission
 
 [Term]
 id: GO:0050807 ! regulation of synapse organization
@@ -45226,7 +45226,7 @@
 
 [Term]
 id: GO:0051966 ! regulation of synaptic transmission, glutamatergic
-is_a: GO:0050804 {is_inferred="true"} ! modulation of synaptic transmission
+is_a: GO:0050804 {is_inferred="true"} ! modulation of chemical synaptic transmission
 
 [Term]
 id: GO:0051967 ! negative regulation of synaptic transmission, glutamatergic
@@ -45968,7 +45968,7 @@
 
 [Term]
 id: GO:0060092 ! regulation of synaptic transmission, glycinergic
-is_a: GO:0050804 {is_inferred="true"} ! modulation of synaptic transmission
+is_a: GO:0050804 {is_inferred="true"} ! modulation of chemical synaptic transmission
 
 [Term]
 id: GO:0060093 ! negative regulation of synaptic transmission, glycinergic
@@ -59446,7 +59446,7 @@
 id: GO:0098815 ! modulation of excitatory postsynaptic potential
 is_a: GO:0009966 {is_inferred="true"} ! regulation of signal transduction
 is_a: GO:0042391 {is_inferred="true"} ! regulation of membrane potential
-is_a: GO:0050804 {is_inferred="true"} ! modulation of synaptic transmission
+is_a: GO:0050804 {is_inferred="true"} ! modulation of chemical synaptic transmission
 
 [Term]
 id: GO:0098826 ! endoplasmic reticulum tubular network membrane
@@ -59460,7 +59460,7 @@
 id: GO:0098828 ! modulation of inhibitory postsynaptic potential
 is_a: GO:0009966 {is_inferred="true"} ! regulation of signal transduction
 is_a: GO:0042391 {is_inferred="true"} ! regulation of membrane potential
-is_a: GO:0050804 {is_inferred="true"} ! modulation of synaptic transmission
+is_a: GO:0050804 {is_inferred="true"} ! modulation of chemical synaptic transmission
 
 [Term]
 id: GO:0098829 ! intestinal folate absorption
@@ -59643,20 +59643,17 @@
 
 [Term]
 id: GO:0098888 ! extrinsic component of presynaptic membrane
-is_a: GO:0019897 {is_inferred="true"} ! extrinsic component of plasma membrane
-is_a: GO:0044456 {is_inferred="true"} ! synapse part
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0099243 {is_inferred="true"} ! extrinsic component of synaptic membrane
 
 [Term]
 id: GO:0098889 ! intrinsic component of presynaptic membrane
-is_a: GO:0031226 {is_inferred="true"} ! intrinsic component of plasma membrane
-is_a: GO:0044456 {is_inferred="true"} ! synapse part
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0099240 {is_inferred="true"} ! intrinsic component of synaptic membrane
 
 [Term]
 id: GO:0098890 ! extrinsic component of postsynaptic membrane
-is_a: GO:0019897 {is_inferred="true"} ! extrinsic component of plasma membrane
-is_a: GO:0044456 {is_inferred="true"} ! synapse part
+is_a: GO:0099243 {is_inferred="true"} ! extrinsic component of synaptic membrane
 
 [Term]
 id: GO:0098891 ! extrinsic component of presynaptic active zone membrane
@@ -59834,8 +59831,7 @@
 
 [Term]
 id: GO:0098936 ! intrinsic component of postsynaptic membrane
-is_a: GO:0031226 {is_inferred="true"} ! intrinsic component of plasma membrane
-is_a: GO:0044456 {is_inferred="true"} ! synapse part
+is_a: GO:0099240 {is_inferred="true"} ! intrinsic component of synaptic membrane
 
 [Term]
 id: GO:0098937 ! anterograde dendritic transport
@@ -60042,7 +60038,7 @@
 
 [Term]
 id: GO:0098987 ! regulation of modification of synapse structure, modulating synaptic transmission
-is_a: GO:0050804 {is_inferred="true"} ! modulation of synaptic transmission
+is_a: GO:0050804 {is_inferred="true"} ! modulation of chemical synaptic transmission
 
 [Term]
 id: GO:0098988 ! G-protein coupled glutamate receptor activity
@@ -60145,13 +60141,13 @@
 
 [Term]
 id: GO:0099025 ! anchored component of postsynaptic membrane
-is_a: GO:0046658 {is_inferred="true"} ! anchored component of plasma membrane
 is_a: GO:0098936 {is_inferred="true"} ! intrinsic component of postsynaptic membrane
+is_a: GO:0099144 {is_inferred="true"} ! anchored component of synaptic membrane
 
 [Term]
 id: GO:0099026 ! anchored component of presynaptic membrane
-is_a: GO:0046658 {is_inferred="true"} ! anchored component of plasma membrane
 is_a: GO:0098889 {is_inferred="true"} ! intrinsic component of presynaptic membrane
+is_a: GO:0099144 {is_inferred="true"} ! anchored component of synaptic membrane
 
 [Term]
 id: GO:0099027 ! anchored component of presynaptic endocytic zone membrane
@@ -60248,13 +60244,13 @@
 
 [Term]
 id: GO:0099055 ! integral component of postsynaptic membrane
-is_a: GO:0005887 {is_inferred="true"} ! integral component of plasma membrane
 is_a: GO:0098936 {is_inferred="true"} ! intrinsic component of postsynaptic membrane
+is_a: GO:0099699 {is_inferred="true"} ! integral component of synaptic membrane
 
 [Term]
 id: GO:0099056 ! integral component of presynaptic membrane
-is_a: GO:0005887 {is_inferred="true"} ! integral component of plasma membrane
 is_a: GO:0098889 {is_inferred="true"} ! intrinsic component of presynaptic membrane
+is_a: GO:0099699 {is_inferred="true"} ! integral component of synaptic membrane
 
 [Term]
 id: GO:0099057 ! integral component of presynaptic endocytic zone membrane
@@ -60542,6 +60538,11 @@
 is_a: GO:0099569 {is_inferred="true"} ! presynaptic cytoskeleton
 
 [Term]
+id: GO:0099144 ! anchored component of synaptic membrane
+is_a: GO:0046658 {is_inferred="true"} ! anchored component of plasma membrane
+is_a: GO:0099240 {is_inferred="true"} ! intrinsic component of synaptic membrane
+
+[Term]
 id: GO:0099145 ! regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane
 is_a: GO:0017157 {is_inferred="true"} ! regulation of exocytosis
 is_a: GO:0033157 {is_inferred="true"} ! regulation of intracellular protein transport
@@ -60553,6 +60554,16 @@
 is_a: GO:1905475 {is_inferred="true"} ! regulation of protein localization to membrane
 
 [Term]
+id: GO:0099240 ! intrinsic component of synaptic membrane
+is_a: GO:0031226 {is_inferred="true"} ! intrinsic component of plasma membrane
+is_a: GO:0044456 {is_inferred="true"} ! synapse part
+
+[Term]
+id: GO:0099243 ! extrinsic component of synaptic membrane
+is_a: GO:0019897 {is_inferred="true"} ! extrinsic component of plasma membrane
+is_a: GO:0044456 {is_inferred="true"} ! synapse part
+
+[Term]
 id: GO:0099400 ! caveola neck
 is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
 
@@ -60662,15 +60673,15 @@
 
 [Term]
 id: GO:0099546 ! protein catabolic process, modulating synaptic transmission
-is_a: GO:0050804 {is_inferred="true"} ! modulation of synaptic transmission
+is_a: GO:0050804 {is_inferred="true"} ! modulation of chemical synaptic transmission
 
 [Term]
 id: GO:0099547 ! regulation of translation at synapse, modulating synaptic transmission
-is_a: GO:0050804 {is_inferred="true"} ! modulation of synaptic transmission
+is_a: GO:0050804 {is_inferred="true"} ! modulation of chemical synaptic transmission
 
 [Term]
 id: GO:0099550 ! trans-synaptic signaling, modulating synaptic transmission
-is_a: GO:0050804 {is_inferred="true"} ! modulation of synaptic transmission
+is_a: GO:0050804 {is_inferred="true"} ! modulation of chemical synaptic transmission
 
 [Term]
 id: GO:0099551 ! trans-synaptic signaling by neuropeptide, modulating synaptic transmission
@@ -60706,7 +60717,7 @@
 
 [Term]
 id: GO:0099564 ! modification of synaptic structure, modulating synaptic transmission
-is_a: GO:0050804 {is_inferred="true"} ! modulation of synaptic transmission
+is_a: GO:0050804 {is_inferred="true"} ! modulation of chemical synaptic transmission
 
 [Term]
 id: GO:0099565 ! chemical synaptic transmission, postsynaptic
@@ -60740,7 +60751,7 @@
 
 [Term]
 id: GO:0099574 ! regulation of protein catabolic process at synapse, modulating synaptic transmission
-is_a: GO:0050804 {is_inferred="true"} ! modulation of synaptic transmission
+is_a: GO:0050804 {is_inferred="true"} ! modulation of chemical synaptic transmission
 
 [Term]
 id: GO:0099575 ! regulation of protein catabolic process at presynapse, modulating synaptic transmission
@@ -60920,6 +60931,11 @@
 is_a: GO:0072594 {is_inferred="true"} ! establishment of protein localization to organelle
 
 [Term]
+id: GO:0099699 ! integral component of synaptic membrane
+is_a: GO:0005887 {is_inferred="true"} ! integral component of plasma membrane
+is_a: GO:0099240 {is_inferred="true"} ! intrinsic component of synaptic membrane
+
+[Term]
 id: GO:0099703 ! induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration
 is_a: GO:0099531 {is_inferred="true"} ! presynaptic process involved in chemical synaptic transmission
 is_a: GO:2000302 {is_inferred="true"} ! positive regulation of synaptic vesicle exocytosis
@@ -62058,7 +62074,7 @@
 
 [Term]
 id: GO:1900073 ! regulation of neuromuscular synaptic transmission
-is_a: GO:0050804 {is_inferred="true"} ! modulation of synaptic transmission
+is_a: GO:0050804 {is_inferred="true"} ! modulation of chemical synaptic transmission
 
 [Term]
 id: GO:1900074 ! negative regulation of neuromuscular synaptic transmission
------------------------------------------------------------------------
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changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42681)
+++ go_inferences.obo	(working copy)
@@ -58443,10 +58443,6 @@
 is_a: GO:0044445 {is_inferred="true"} ! cytosolic part
 
 [Term]
-id: GO:0097352 ! autophagosome maturation
-is_a: GO:0097576 {is_inferred="true"} ! vacuole fusion
-
-[Term]
 id: GO:0097355 ! protein localization to heterochromatin
 is_a: GO:0071168 {is_inferred="true"} ! protein localization to chromatin
 
@@ -67456,16 +67452,16 @@
 
 [Term]
 id: GO:1901096 ! regulation of autophagosome maturation
-is_a: GO:0044088 {is_inferred="true"} ! regulation of vacuole organization
+is_a: GO:0043244 {is_inferred="true"} ! regulation of protein complex disassembly
 
 [Term]
 id: GO:1901097 ! negative regulation of autophagosome maturation
-is_a: GO:0010639 {is_inferred="true"} ! negative regulation of organelle organization
+is_a: GO:0043242 {is_inferred="true"} ! negative regulation of protein complex disassembly
 is_a: GO:1901096 {is_inferred="true"} ! regulation of autophagosome maturation
 
 [Term]
 id: GO:1901098 ! positive regulation of autophagosome maturation
-is_a: GO:0044090 {is_inferred="true"} ! positive regulation of vacuole organization
+is_a: GO:0043243 {is_inferred="true"} ! positive regulation of protein complex disassembly
 is_a: GO:1901096 {is_inferred="true"} ! regulation of autophagosome maturation
 
 [Term]
------------------------------------------------------------------------
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changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42680)
+++ go_inferences.obo	(working copy)
@@ -61402,6 +61402,24 @@
 is_a: GO:0032956 {is_inferred="true"} ! regulation of actin cytoskeleton organization
 
 [Term]
+id: GO:0110021 ! cardiac muscle myoblast proliferation
+is_a: GO:0051450 {is_inferred="true"} ! myoblast proliferation
+
+[Term]
+id: GO:0110022 ! regulation of cardiac muscle myoblast proliferation
+is_a: GO:2000291 {is_inferred="true"} ! regulation of myoblast proliferation
+
+[Term]
+id: GO:0110023 ! negative regulation of cardiac muscle myoblast proliferation
+is_a: GO:0110022 {is_inferred="true"} ! regulation of cardiac muscle myoblast proliferation
+is_a: GO:2000818 {is_inferred="true"} ! negative regulation of myoblast proliferation
+
+[Term]
+id: GO:0110024 ! positive regulation of cardiac muscle myoblast proliferation
+is_a: GO:0110022 {is_inferred="true"} ! regulation of cardiac muscle myoblast proliferation
+is_a: GO:2000288 {is_inferred="true"} ! positive regulation of myoblast proliferation
+
+[Term]
 id: GO:0120006 ! regulation of glutamatergic neuron differentiation
 is_a: GO:0045664 {is_inferred="true"} ! regulation of neuron differentiation
 
------------------------------------------------------------------------
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changes in entailments

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changes in entailments

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synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42676)
+++ go_inferences.obo	(working copy)
@@ -49469,6 +49469,13 @@
 is_a: GO:0051640 {is_inferred="true"} ! organelle localization
 
 [Term]
+id: GO:0061907 ! negative regulation of AMPA receptor activity
+is_a: GO:1900450 {is_inferred="true"} ! negative regulation of glutamate receptor signaling pathway
+is_a: GO:2000272 {is_inferred="true"} ! negative regulation of receptor activity
+is_a: GO:2000311 {is_inferred="true"} ! regulation of AMPA receptor activity
+is_a: GO:2001258 {is_inferred="true"} ! negative regulation of cation channel activity
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
------------------------------------------------------------------------
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changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42675)
+++ go_inferences.obo	(working copy)
@@ -33433,8 +33433,9 @@
 is_a: GO:1902936 {is_inferred="true"} ! phosphatidylinositol bisphosphate binding
 
 [Term]
-id: GO:0043328 ! protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
-is_a: GO:0006623 {is_inferred="true"} ! protein targeting to vacuole
+id: GO:0043328 ! protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
+is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
+is_a: GO:0072666 {is_inferred="true"} ! establishment of protein localization to vacuole
 
 [Term]
 id: GO:0043329 ! protein targeting to membrane involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
------------------------------------------------------------------------
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changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42673)
+++ go_inferences.obo	(working copy)
@@ -30238,9 +30238,8 @@
 is_a: GO:1902653 {is_inferred="true"} ! secondary alcohol biosynthetic process
 
 [Term]
-id: GO:0036228 ! protein targeting to nuclear inner membrane
-is_a: GO:0051169 {is_inferred="true"} ! nuclear transport
-is_a: GO:0072594 {is_inferred="true"} ! establishment of protein localization to organelle
+id: GO:0036228 ! protein localization to nuclear inner membrane
+is_a: GO:0072657 {is_inferred="true"} ! protein localization to membrane
 is_a: GO:0090435 {is_inferred="true"} ! protein localization to nuclear envelope
 
 [Term]
------------------------------------------------------------------------
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changes in entailments

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synced

changes in entailments

------------------------------------------------------------------------
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synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42666)
+++ go_inferences.obo	(working copy)
@@ -97391,8 +97391,7 @@
 
 [Term]
 id: GO:2001159 ! regulation of CVT pathway
-is_a: GO:1903335 {is_inferred="true"} ! regulation of vacuolar transport
-is_a: GO:1903533 {is_inferred="true"} ! regulation of protein targeting
+is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
 
 [Term]
 id: GO:2001160 ! regulation of histone H3-K79 methylation
------------------------------------------------------------------------
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synced

changes in entailments

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synced

changes in entailments

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changes in entailments

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changes in entailments

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changes in entailments

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changes in entailments

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synced

changes in entailments

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synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42653)
+++ go_inferences.obo	(working copy)
@@ -76462,16 +76462,22 @@
 
 [Term]
 id: GO:1902959 ! regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
+is_a: GO:0052548 {is_inferred="true"} ! regulation of endopeptidase activity
+is_a: GO:1902991 {is_inferred="true"} ! regulation of amyloid precursor protein catabolic process
 is_a: GO:1905245 {is_inferred="true"} ! regulation of aspartic-type peptidase activity
 
 [Term]
 id: GO:1902960 ! negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
+is_a: GO:0010951 {is_inferred="true"} ! negative regulation of endopeptidase activity
 is_a: GO:1902959 {is_inferred="true"} ! regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
+is_a: GO:1902992 {is_inferred="true"} ! negative regulation of amyloid precursor protein catabolic process
 is_a: GO:1905246 {is_inferred="true"} ! negative regulation of aspartic-type peptidase activity
 
 [Term]
 id: GO:1902961 ! positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
+is_a: GO:0010950 {is_inferred="true"} ! positive regulation of endopeptidase activity
 is_a: GO:1902959 {is_inferred="true"} ! regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
+is_a: GO:1902993 {is_inferred="true"} ! positive regulation of amyloid precursor protein catabolic process
 is_a: GO:1905247 {is_inferred="true"} ! positive regulation of aspartic-type peptidase activity
 
 [Term]
------------------------------------------------------------------------
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changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42652)
+++ go_inferences.obo	(working copy)
@@ -49465,6 +49465,10 @@
 is_a: GO:0061901 {is_inferred="true"} ! regulation of 1-phosphatidylinositol-3-kinase activity
 
 [Term]
+id: GO:0061906 ! autophagosome localization
+is_a: GO:0051640 {is_inferred="true"} ! organelle localization
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
------------------------------------------------------------------------
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synced

changes in entailments

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synced

changes in entailments

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synced

changes in entailments

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synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42648)
+++ go_inferences.obo	(working copy)
@@ -30239,7 +30239,8 @@
 
 [Term]
 id: GO:0036228 ! protein targeting to nuclear inner membrane
-is_a: GO:0044744 {is_inferred="true"} ! protein targeting to nucleus
+is_a: GO:0051169 {is_inferred="true"} ! nuclear transport
+is_a: GO:0072594 {is_inferred="true"} ! establishment of protein localization to organelle
 is_a: GO:0090435 {is_inferred="true"} ! protein localization to nuclear envelope
 
 [Term]
@@ -31269,9 +31270,9 @@
 
 [Term]
 id: GO:0042306 ! regulation of protein import into nucleus
+is_a: GO:0033157 {is_inferred="true"} ! regulation of intracellular protein transport
 is_a: GO:0046822 {is_inferred="true"} ! regulation of nucleocytoplasmic transport
 is_a: GO:1900180 {is_inferred="true"} ! regulation of protein localization to nucleus
-is_a: GO:1903533 {is_inferred="true"} ! regulation of protein targeting
 is_a: GO:1904589 {is_inferred="true"} ! regulation of protein import
 
 [Term]
@@ -34917,13 +34918,6 @@
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
-id: GO:0044744 ! protein targeting to nucleus
-is_a: GO:0006605 {is_inferred="true"} ! protein targeting
-is_a: GO:0034504 {is_inferred="true"} ! protein localization to nucleus
-is_a: GO:0051169 {is_inferred="true"} ! nuclear transport
-is_a: GO:0072594 {is_inferred="true"} ! establishment of protein localization to organelle
-
-[Term]
 id: GO:0044745 ! amino acid transmembrane import
 is_a: GO:0003333 {is_inferred="true"} ! amino acid transmembrane transport
 is_a: GO:0043090 {is_inferred="true"} ! amino acid import
------------------------------------------------------------------------
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synced

changes in entailments

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synced

changes in entailments

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synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42638)
+++ go_inferences.obo	(working copy)
@@ -13456,6 +13456,10 @@
 is_a: GO:0006446 {is_inferred="true"} ! regulation of translational initiation
 
 [Term]
+id: GO:0012507 ! ER to Golgi transport vesicle membrane
+is_a: GO:0030660 {is_inferred="true"} ! Golgi-associated vesicle membrane
+
+[Term]
 id: GO:0014004 ! microglia differentiation
 is_a: GO:0030225 {is_inferred="true"} ! macrophage differentiation
 
@@ -16558,6 +16562,10 @@
 is_a: GO:0016241 {is_inferred="true"} ! regulation of macroautophagy
 
 [Term]
+id: GO:0016240 ! autophagosome membrane docking
+is_a: GO:0140056 {is_inferred="true"} ! organelle localization by membrane tethering
+
+[Term]
 id: GO:0016241 ! regulation of macroautophagy
 is_a: GO:0010506 {is_inferred="true"} ! regulation of autophagy
 
@@ -19957,6 +19965,10 @@
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
 [Term]
+id: GO:0030127 ! COPII vesicle coat
+is_a: GO:0044431 {is_inferred="true"} ! Golgi apparatus part
+
+[Term]
 id: GO:0030129 ! clathrin coat of synaptic vesicle
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
@@ -22996,7 +23008,7 @@
 
 [Term]
 id: GO:0032122 ! oral apparatus organization
-is_a: GO:0030030 {is_inferred="true"} ! cell projection organization
+is_a: GO:0016043 {is_inferred="true"} ! cellular component organization
 
 [Term]
 id: GO:0032124 ! macronucleus organization
@@ -52853,6 +52865,11 @@
 is_a: GO:0030176 {is_inferred="true"} ! integral component of endoplasmic reticulum membrane
 
 [Term]
+id: GO:0071562 ! nucleus-vacuole junction assembly
+is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
+is_a: GO:0140056 {is_inferred="true"} ! organelle localization by membrane tethering
+
+[Term]
 id: GO:0071574 ! protein localization to medial cortex
 is_a: GO:0072741 {is_inferred="true"} ! protein localization to cell division site
 
@@ -56561,7 +56578,7 @@
 
 [Term]
 id: GO:0090114 ! COPII-coated vesicle budding
-is_a: GO:0006900 {is_inferred="true"} ! membrane budding
+is_a: GO:0048194 {is_inferred="true"} ! Golgi vesicle budding
 
 [Term]
 id: GO:0090118 ! receptor-mediated endocytosis involved in cholesterol transport
@@ -61299,6 +61316,7 @@
 
 [Term]
 id: GO:0106020 ! regulation of vesicle docking
+is_a: GO:0060341 {is_inferred="true"} ! regulation of cellular localization
 is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
 
 [Term]
@@ -61681,6 +61699,10 @@
 is_a: GO:0010467 {is_inferred="true"} ! gene expression
 
 [Term]
+id: GO:0140056 ! organelle localization by membrane tethering
+is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
+
+[Term]
 id: GO:1900000 ! regulation of anthocyanin catabolic process
 is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
 is_a: GO:0031537 {is_inferred="true"} ! regulation of anthocyanin metabolic process
@@ -91203,7 +91225,7 @@
 is_a: GO:1904144 {is_inferred="true"} ! phosphatidylinositol phosphate phosphatase complex
 
 [Term]
-id: GO:1990456 ! mitochondrion-ER tethering
+id: GO:1990456 ! mitochondrion-endoplasmic reticulum membrane tethering
 is_a: GO:0016043 {is_inferred="true"} ! cellular component organization
 
 [Term]
------------------------------------------------------------------------
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synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42628)
+++ go_inferences.obo	(working copy)
@@ -61587,6 +61587,20 @@
 is_a: GO:1904305 {is_inferred="true"} ! negative regulation of gastro-intestinal system smooth muscle contraction
 
 [Term]
+id: GO:0120074 ! regulation of endocardial cushion cell differentiation
+is_a: GO:1905207 {is_inferred="true"} ! regulation of cardiocyte differentiation
+
+[Term]
+id: GO:0120075 ! positive regulation of endocardial cushion cell differentiation
+is_a: GO:0120074 {is_inferred="true"} ! regulation of endocardial cushion cell differentiation
+is_a: GO:1905209 {is_inferred="true"} ! positive regulation of cardiocyte differentiation
+
+[Term]
+id: GO:0120076 ! negative regulation of endocardial cushion cell differentiation
+is_a: GO:0120074 {is_inferred="true"} ! regulation of endocardial cushion cell differentiation
+is_a: GO:1905208 {is_inferred="true"} ! negative regulation of cardiocyte differentiation
+
+[Term]
 id: GO:0140009 ! L-aspartate import across plasma membrane
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 is_a: GO:0089712 {is_inferred="true"} ! L-aspartate transmembrane transport
------------------------------------------------------------------------
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synced

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synced

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synced

changes in entailments

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synced

changes in entailments

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changes in entailments

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changes in entailments

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synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42614)
+++ go_inferences.obo	(working copy)
@@ -1139,12 +1139,12 @@
 
 [Term]
 id: GO:0000964 ! mitochondrial RNA 5'-end processing
-is_a: GO:0000963 {is_inferred="true"} ! mitochondrial RNA processing
+is_a: GO:0000959 {is_inferred="true"} ! mitochondrial RNA metabolic process
 is_a: GO:0000966 {is_inferred="true"} ! RNA 5'-end processing
 
 [Term]
 id: GO:0000965 ! mitochondrial RNA 3'-end processing
-is_a: GO:0000963 {is_inferred="true"} ! mitochondrial RNA processing
+is_a: GO:0000959 {is_inferred="true"} ! mitochondrial RNA metabolic process
 is_a: GO:0031123 {is_inferred="true"} ! RNA 3'-end processing
 
 [Term]
@@ -51214,7 +51214,6 @@
 [Term]
 id: GO:0070900 ! mitochondrial tRNA modification
 is_a: GO:0006400 {is_inferred="true"} ! tRNA modification
-is_a: GO:0090646 {is_inferred="true"} ! mitochondrial tRNA processing
 is_a: GO:1900864 {is_inferred="true"} ! mitochondrial RNA modification
 
 [Term]
@@ -57887,7 +57886,7 @@
 
 [Term]
 id: GO:0090615 ! mitochondrial mRNA processing
-is_a: GO:0000963 {is_inferred="true"} ! mitochondrial RNA processing
+is_a: GO:0000959 {is_inferred="true"} ! mitochondrial RNA metabolic process
 
 [Term]
 id: GO:0090616 ! mitochondrial mRNA 3'-end processing
@@ -58651,7 +58650,6 @@
 [Term]
 id: GO:0097745 ! mitochondrial tRNA 5'-end processing
 is_a: GO:0000964 {is_inferred="true"} ! mitochondrial RNA 5'-end processing
-is_a: GO:0090646 {is_inferred="true"} ! mitochondrial tRNA processing
 is_a: GO:0099116 {is_inferred="true"} ! tRNA 5'-end processing
 
 [Term]
@@ -61665,6 +61663,10 @@
 is_a: GO:0140049 {is_inferred="true"} ! regulation of endocardial cushion to mesenchymal transition
 
 [Term]
+id: GO:0140053 ! mitochondrial gene expression
+is_a: GO:0010467 {is_inferred="true"} ! gene expression
+
+[Term]
 id: GO:1900000 ! regulation of anthocyanin catabolic process
 is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
 is_a: GO:0031537 {is_inferred="true"} ! regulation of anthocyanin metabolic process
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42610)
+++ go_inferences.obo	(working copy)
@@ -45815,6 +45815,10 @@
 is_a: GO:0010033 {is_inferred="true"} ! response to organic substance
 
 [Term]
+id: GO:0055098 ! response to low-density lipoprotein particle stimulus
+is_a: GO:0071402 {is_inferred="true"} ! cellular response to lipoprotein particle stimulus
+
+[Term]
 id: GO:0055107 ! Golgi to secretory granule transport
 is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
 
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

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changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42609)
+++ go_inferences.obo	(working copy)
@@ -61646,6 +61646,21 @@
 is_a: GO:0071421 {is_inferred="true"} ! manganese ion transmembrane transport
 
 [Term]
+id: GO:0140049 ! regulation of endocardial cushion to mesenchymal transition
+is_a: GO:0010717 {is_inferred="true"} ! regulation of epithelial to mesenchymal transition
+is_a: GO:2000826 {is_inferred="true"} ! regulation of heart morphogenesis
+
+[Term]
+id: GO:0140050 ! negative regulation of endocardial cushion to mesenchymal transition
+is_a: GO:0010719 {is_inferred="true"} ! negative regulation of epithelial to mesenchymal transition
+is_a: GO:0140049 {is_inferred="true"} ! regulation of endocardial cushion to mesenchymal transition
+
+[Term]
+id: GO:0140051 ! positive regulation of endocardial cushion to mesenchymal transition
+is_a: GO:0010718 {is_inferred="true"} ! positive regulation of epithelial to mesenchymal transition
+is_a: GO:0140049 {is_inferred="true"} ! regulation of endocardial cushion to mesenchymal transition
+
+[Term]
 id: GO:1900000 ! regulation of anthocyanin catabolic process
 is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
 is_a: GO:0031537 {is_inferred="true"} ! regulation of anthocyanin metabolic process
@@ -95634,17 +95649,16 @@
 
 [Term]
 id: GO:2000800 ! regulation of endocardial cushion to mesenchymal transition involved in heart valve formation
-is_a: GO:0010717 {is_inferred="true"} ! regulation of epithelial to mesenchymal transition
-is_a: GO:2000826 {is_inferred="true"} ! regulation of heart morphogenesis
+is_a: GO:0140049 {is_inferred="true"} ! regulation of endocardial cushion to mesenchymal transition
 
 [Term]
 id: GO:2000801 ! negative regulation of endocardial cushion to mesenchymal transition involved in heart valve formation
-is_a: GO:0010719 {is_inferred="true"} ! negative regulation of epithelial to mesenchymal transition
+is_a: GO:0140050 {is_inferred="true"} ! negative regulation of endocardial cushion to mesenchymal transition
 is_a: GO:2000800 {is_inferred="true"} ! regulation of endocardial cushion to mesenchymal transition involved in heart valve formation
 
 [Term]
 id: GO:2000802 ! positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation
-is_a: GO:0010718 {is_inferred="true"} ! positive regulation of epithelial to mesenchymal transition
+is_a: GO:0140051 {is_inferred="true"} ! positive regulation of endocardial cushion to mesenchymal transition
 is_a: GO:2000800 {is_inferred="true"} ! regulation of endocardial cushion to mesenchymal transition involved in heart valve formation
 
 [Term]
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42528)
+++ go_inferences.obo	(working copy)
@@ -61642,6 +61642,10 @@
 is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
 
 [Term]
+id: GO:0140048 ! manganese ion export from cell
+is_a: GO:0071421 {is_inferred="true"} ! manganese ion transmembrane transport
+
+[Term]
 id: GO:1900000 ! regulation of anthocyanin catabolic process
 is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
 is_a: GO:0031537 {is_inferred="true"} ! regulation of anthocyanin metabolic process
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42508)
+++ go_inferences.obo	(working copy)
@@ -49438,6 +49438,23 @@
 is_a: GO:0001775 {is_inferred="true"} ! cell activation
 
 [Term]
+id: GO:0061901 ! regulation of 1-phosphatidylinositol-3-kinase activity
+is_a: GO:0010511 {is_inferred="true"} ! regulation of phosphatidylinositol biosynthetic process
+is_a: GO:0043551 {is_inferred="true"} ! regulation of phosphatidylinositol 3-kinase activity
+
+[Term]
+id: GO:0061902 ! negative regulation of 1-phosphatidylinositol-3-kinase activity
+is_a: GO:0010512 {is_inferred="true"} ! negative regulation of phosphatidylinositol biosynthetic process
+is_a: GO:0043553 {is_inferred="true"} ! negative regulation of phosphatidylinositol 3-kinase activity
+is_a: GO:0061901 {is_inferred="true"} ! regulation of 1-phosphatidylinositol-3-kinase activity
+
+[Term]
+id: GO:0061903 ! positive regulation of 1-phosphatidylinositol-3-kinase activity
+is_a: GO:0010513 {is_inferred="true"} ! positive regulation of phosphatidylinositol biosynthetic process
+is_a: GO:0043552 {is_inferred="true"} ! positive regulation of phosphatidylinositol 3-kinase activity
+is_a: GO:0061901 {is_inferred="true"} ! regulation of 1-phosphatidylinositol-3-kinase activity
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42504)
+++ go_inferences.obo	(working copy)
@@ -8074,11 +8074,6 @@
 is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
-id: GO:0007101 ! male meiosis centrosome cycle
-is_a: GO:0007098 {is_inferred="true"} ! centrosome cycle
-is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
-
-[Term]
 id: GO:0007116 ! regulation of cell budding
 is_a: GO:0051302 {is_inferred="true"} ! regulation of cell division
 is_a: GO:1903664 {is_inferred="true"} ! regulation of asexual reproduction
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42450)
+++ go_inferences.obo	(working copy)
@@ -46393,9 +46393,9 @@
 [Term]
 id: GO:0060297 ! regulation of sarcomere organization
 is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
-is_a: GO:0032956 {is_inferred="true"} ! regulation of actin cytoskeleton organization
 is_a: GO:0051153 {is_inferred="true"} ! regulation of striated muscle cell differentiation
 is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
+is_a: GO:0110020 {is_inferred="true"} ! regulation of actomyosin structure organization
 is_a: GO:1902115 {is_inferred="true"} ! regulation of organelle assembly
 
 [Term]
@@ -61361,6 +61361,10 @@
 is_a: GO:0044452 {is_inferred="true"} ! nucleolar part
 
 [Term]
+id: GO:0110020 ! regulation of actomyosin structure organization
+is_a: GO:0032956 {is_inferred="true"} ! regulation of actin cytoskeleton organization
+
+[Term]
 id: GO:0120006 ! regulation of glutamatergic neuron differentiation
 is_a: GO:0045664 {is_inferred="true"} ! regulation of neuron differentiation
 
@@ -87515,8 +87519,8 @@
 [Term]
 id: GO:1905304 ! regulation of cardiac myofibril assembly
 is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
-is_a: GO:0032956 {is_inferred="true"} ! regulation of actin cytoskeleton organization
 is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
+is_a: GO:0110020 {is_inferred="true"} ! regulation of actomyosin structure organization
 is_a: GO:1902115 {is_inferred="true"} ! regulation of organelle assembly
 is_a: GO:2000725 {is_inferred="true"} ! regulation of cardiac muscle cell differentiation
 
@@ -93819,8 +93823,8 @@
 [Term]
 id: GO:2000431 ! regulation of cytokinesis, actomyosin contractile ring assembly
 is_a: GO:0032954 {is_inferred="true"} ! regulation of cytokinetic process
-is_a: GO:0032956 {is_inferred="true"} ! regulation of actin cytoskeleton organization
 is_a: GO:0044087 {is_inferred="true"} ! regulation of cellular component biogenesis
+is_a: GO:0110020 {is_inferred="true"} ! regulation of actomyosin structure organization
 
 [Term]
 id: GO:2000432 ! negative regulation of cytokinesis, actomyosin contractile ring assembly
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42446)
+++ go_inferences.obo	(working copy)
@@ -6544,17 +6544,15 @@
 is_a: GO:0051170 {is_inferred="true"} ! nuclear import
 
 [Term]
-id: GO:0006406 ! mRNA export from nucleus
-is_a: GO:0006913 {is_inferred="true"} ! nucleocytoplasmic transport
+id: GO:0006407 ! rRNA export from nucleus
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
-id: GO:0006407 ! rRNA export from nucleus
-is_a: GO:0006913 {is_inferred="true"} ! nucleocytoplasmic transport
+id: GO:0006408 ! snRNA export from nucleus
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:0006409 ! tRNA export from nucleus
-is_a: GO:0006913 {is_inferred="true"} ! nucleocytoplasmic transport
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
@@ -6969,9 +6967,8 @@
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0017038 {is_inferred="true"} ! protein import
 is_a: GO:0034504 {is_inferred="true"} ! protein localization to nucleus
-is_a: GO:0051169 {is_inferred="true"} ! nuclear transport
 is_a: GO:0072594 {is_inferred="true"} ! establishment of protein localization to organelle
-is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
+is_a: GO:1902593 {is_inferred="true"} ! single-organism nuclear import
 
 [Term]
 id: GO:0006608 ! snRNP protein import into nucleus
@@ -6978,10 +6975,6 @@
 is_a: GO:0071167 {is_inferred="true"} ! ribonucleoprotein complex import into nucleus
 
 [Term]
-id: GO:0006611 ! protein export from nucleus
-is_a: GO:0006913 {is_inferred="true"} ! nucleocytoplasmic transport
-
-[Term]
 id: GO:0006612 ! protein targeting to membrane
 is_a: GO:0006605 {is_inferred="true"} ! protein targeting
 is_a: GO:0090150 {is_inferred="true"} ! establishment of protein localization to membrane
@@ -30746,6 +30739,10 @@
 is_a: GO:0044423 {is_inferred="true"} ! virion part
 
 [Term]
+id: GO:0039674 ! exit of virus from host cell nucleus
+is_a: GO:1902583 {is_inferred="true"} ! multi-organism intracellular transport
+
+[Term]
 id: GO:0039708 ! nuclear capsid assembly
 is_a: GO:0019069 {is_inferred="true"} ! viral capsid assembly
 
@@ -31265,6 +31262,7 @@
 
 [Term]
 id: GO:0042306 ! regulation of protein import into nucleus
+is_a: GO:0046822 {is_inferred="true"} ! regulation of nucleocytoplasmic transport
 is_a: GO:1900180 {is_inferred="true"} ! regulation of protein localization to nucleus
 is_a: GO:1903533 {is_inferred="true"} ! regulation of protein targeting
 is_a: GO:1904589 {is_inferred="true"} ! regulation of protein import
@@ -31272,6 +31270,7 @@
 [Term]
 id: GO:0042307 ! positive regulation of protein import into nucleus
 is_a: GO:0042306 {is_inferred="true"} ! regulation of protein import into nucleus
+is_a: GO:0046824 {is_inferred="true"} ! positive regulation of nucleocytoplasmic transport
 is_a: GO:0090316 {is_inferred="true"} ! positive regulation of intracellular protein transport
 is_a: GO:1900182 {is_inferred="true"} ! positive regulation of protein localization to nucleus
 is_a: GO:1904591 {is_inferred="true"} ! positive regulation of protein import
@@ -31279,6 +31278,7 @@
 [Term]
 id: GO:0042308 ! negative regulation of protein import into nucleus
 is_a: GO:0042306 {is_inferred="true"} ! regulation of protein import into nucleus
+is_a: GO:0046823 {is_inferred="true"} ! negative regulation of nucleocytoplasmic transport
 is_a: GO:0090317 {is_inferred="true"} ! negative regulation of intracellular protein transport
 is_a: GO:1900181 {is_inferred="true"} ! negative regulation of protein localization to nucleus
 is_a: GO:1904590 {is_inferred="true"} ! negative regulation of protein import
@@ -34911,6 +34911,7 @@
 
 [Term]
 id: GO:0044744 ! protein targeting to nucleus
+is_a: GO:0006605 {is_inferred="true"} ! protein targeting
 is_a: GO:0034504 {is_inferred="true"} ! protein localization to nucleus
 is_a: GO:0051169 {is_inferred="true"} ! nuclear transport
 is_a: GO:0072594 {is_inferred="true"} ! establishment of protein localization to organelle
@@ -40613,29 +40614,35 @@
 [Term]
 id: GO:0046828 ! regulation of RNA import into nucleus
 is_a: GO:0032239 {is_inferred="true"} ! regulation of nucleobase-containing compound transport
+is_a: GO:0046822 {is_inferred="true"} ! regulation of nucleocytoplasmic transport
 
 [Term]
 id: GO:0046829 ! negative regulation of RNA import into nucleus
 is_a: GO:0032240 {is_inferred="true"} ! negative regulation of nucleobase-containing compound transport
+is_a: GO:0046823 {is_inferred="true"} ! negative regulation of nucleocytoplasmic transport
 is_a: GO:0046828 {is_inferred="true"} ! regulation of RNA import into nucleus
 
 [Term]
 id: GO:0046830 ! positive regulation of RNA import into nucleus
 is_a: GO:0032241 {is_inferred="true"} ! positive regulation of nucleobase-containing compound transport
+is_a: GO:0046824 {is_inferred="true"} ! positive regulation of nucleocytoplasmic transport
 is_a: GO:0046828 {is_inferred="true"} ! regulation of RNA import into nucleus
 
 [Term]
 id: GO:0046831 ! regulation of RNA export from nucleus
 is_a: GO:0032239 {is_inferred="true"} ! regulation of nucleobase-containing compound transport
+is_a: GO:0046822 {is_inferred="true"} ! regulation of nucleocytoplasmic transport
 
 [Term]
 id: GO:0046832 ! negative regulation of RNA export from nucleus
 is_a: GO:0032240 {is_inferred="true"} ! negative regulation of nucleobase-containing compound transport
+is_a: GO:0046823 {is_inferred="true"} ! negative regulation of nucleocytoplasmic transport
 is_a: GO:0046831 {is_inferred="true"} ! regulation of RNA export from nucleus
 
 [Term]
 id: GO:0046833 ! positive regulation of RNA export from nucleus
 is_a: GO:0032241 {is_inferred="true"} ! positive regulation of nucleobase-containing compound transport
+is_a: GO:0046824 {is_inferred="true"} ! positive regulation of nucleocytoplasmic transport
 is_a: GO:0046831 {is_inferred="true"} ! regulation of RNA export from nucleus
 
 [Term]
@@ -43449,18 +43456,10 @@
 is_a: GO:1901135 {is_inferred="true"} ! carbohydrate derivative metabolic process
 
 [Term]
-id: GO:0051168 ! nuclear export
-is_a: GO:0006810 {is_inferred="true"} ! transport
-
-[Term]
 id: GO:0051169 ! nuclear transport
 is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
 
 [Term]
-id: GO:0051170 ! nuclear import
-is_a: GO:0006810 {is_inferred="true"} ! transport
-
-[Term]
 id: GO:0051174 ! regulation of phosphorus metabolic process
 is_a: GO:0031323 {is_inferred="true"} ! regulation of cellular metabolic process
 
@@ -44273,25 +44272,17 @@
 is_a: GO:0051516 {is_inferred="true"} ! regulation of bipolar cell growth
 
 [Term]
-id: GO:0051531 ! NFAT protein import into nucleus
-is_a: GO:0006913 {is_inferred="true"} ! nucleocytoplasmic transport
-is_a: GO:1902593 {is_inferred="true"} ! single-organism nuclear import
-
-[Term]
 id: GO:0051532 ! regulation of NFAT protein import into nucleus
 is_a: GO:0042990 {is_inferred="true"} ! regulation of transcription factor import into nucleus
-is_a: GO:0046822 {is_inferred="true"} ! regulation of nucleocytoplasmic transport
 
 [Term]
 id: GO:0051533 ! positive regulation of NFAT protein import into nucleus
 is_a: GO:0042993 {is_inferred="true"} ! positive regulation of transcription factor import into nucleus
-is_a: GO:0046824 {is_inferred="true"} ! positive regulation of nucleocytoplasmic transport
 is_a: GO:0051532 {is_inferred="true"} ! regulation of NFAT protein import into nucleus
 
 [Term]
 id: GO:0051534 ! negative regulation of NFAT protein import into nucleus
 is_a: GO:0042992 {is_inferred="true"} ! negative regulation of transcription factor import into nucleus
-is_a: GO:0046823 {is_inferred="true"} ! negative regulation of nucleocytoplasmic transport
 is_a: GO:0051532 {is_inferred="true"} ! regulation of NFAT protein import into nucleus
 
 [Term]
@@ -51812,8 +51803,8 @@
 
 [Term]
 id: GO:0071167 ! ribonucleoprotein complex import into nucleus
+is_a: GO:0006404 {is_inferred="true"} ! RNA import into nucleus
 is_a: GO:0006606 {is_inferred="true"} ! protein import into nucleus
-is_a: GO:0050658 {is_inferred="true"} ! RNA transport
 
 [Term]
 id: GO:0071169 ! establishment of protein localization to chromatin
@@ -74679,13 +74670,13 @@
 
 [Term]
 id: GO:1902593 ! single-organism nuclear import
-is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
 is_a: GO:0051170 {is_inferred="true"} ! nuclear import
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:1902594 ! multi-organism nuclear import
-is_a: GO:0044766 {is_inferred="true"} ! multi-organism transport
 is_a: GO:0051170 {is_inferred="true"} ! nuclear import
+is_a: GO:1902583 {is_inferred="true"} ! multi-organism intracellular transport
 
 [Term]
 id: GO:1902595 ! regulation of DNA replication origin binding
@@ -90971,9 +90962,7 @@
 [Term]
 id: GO:1990236 ! proteasome core complex import into nucleus
 is_a: GO:0006606 {is_inferred="true"} ! protein import into nucleus
-is_a: GO:0006913 {is_inferred="true"} ! nucleocytoplasmic transport
 is_a: GO:0031503 {is_inferred="true"} ! protein complex localization
-is_a: GO:1902593 {is_inferred="true"} ! single-organism nuclear import
 
 [Term]
 id: GO:1990237 ! sequestration of proteasome core complex in proteasome storage granule
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42444)
+++ go_inferences.obo	(working copy)
@@ -20267,6 +20267,10 @@
 is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
+id: GO:0030382 ! sperm mitochondrion organization
+is_a: GO:0007005 {is_inferred="true"} ! mitochondrion organization
+
+[Term]
 id: GO:0030386 ! ferredoxin:thioredoxin reductase complex
 is_a: GO:1990204 {is_inferred="true"} ! oxidoreductase complex
 
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42441)
+++ go_inferences.obo	(working copy)
@@ -13683,7 +13683,7 @@
 is_a: GO:1902533 {is_inferred="true"} ! positive regulation of intracellular signal transduction
 
 [Term]
-id: GO:0014069 ! postsynaptic density
+id: GO:0014069 ! postsynaptic density of dendrite
 is_a: GO:0099572 {is_inferred="true"} ! postsynaptic specialization
 
 [Term]
@@ -58482,6 +58482,10 @@
 is_a: GO:0051402 {is_inferred="true"} ! neuron apoptotic process
 
 [Term]
+id: GO:0097482 ! muscle cell postsynaptic density
+is_a: GO:0099572 {is_inferred="true"} ! postsynaptic specialization
+
+[Term]
 id: GO:0097488 ! multivesicular body, internal vesicle membrane
 is_a: GO:0044440 {is_inferred="true"} ! endosomal part
 is_a: GO:0098588 {is_inferred="true"} ! bounding membrane of organelle
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42435)
+++ go_inferences.obo	(working copy)
@@ -22533,7 +22533,7 @@
 is_a: GO:0031779 {is_inferred="true"} ! melanocortin receptor binding
 
 [Term]
-id: GO:0031887 ! lipid particle transport along microtubule
+id: GO:0031887 ! lipid droplet transport along microtubule
 is_a: GO:0072384 {is_inferred="true"} ! organelle transport along microtubule
 
 [Term]
@@ -61623,6 +61623,10 @@
 is_a: GO:1990748 {is_inferred="true"} ! cellular detoxification
 
 [Term]
+id: GO:0140042 ! lipid droplet formation
+is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
+
+[Term]
 id: GO:1900000 ! regulation of anthocyanin catabolic process
 is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
 is_a: GO:0031537 {is_inferred="true"} ! regulation of anthocyanin metabolic process
@@ -89349,7 +89353,7 @@
 is_a: GO:1903008 {is_inferred="true"} ! organelle disassembly
 
 [Term]
-id: GO:1905691 ! lipid particle disassembly
+id: GO:1905691 ! lipid droplet disassembly
 is_a: GO:1903008 {is_inferred="true"} ! organelle disassembly
 
 [Term]
@@ -90722,7 +90726,7 @@
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
 
 [Term]
-id: GO:1990044 ! protein localization to lipid particle
+id: GO:1990044 ! protein localization to lipid droplet
 is_a: GO:0033365 {is_inferred="true"} ! protein localization to organelle
 
 [Term]
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42424)
+++ go_inferences.obo	(working copy)
@@ -61619,6 +61619,10 @@
 is_a: GO:0090615 {is_inferred="true"} ! mitochondrial mRNA processing
 
 [Term]
+id: GO:0140041 ! cellular detoxification of methylglyoxal
+is_a: GO:1990748 {is_inferred="true"} ! cellular detoxification
+
+[Term]
 id: GO:1900000 ! regulation of anthocyanin catabolic process
 is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
 is_a: GO:0031537 {is_inferred="true"} ! regulation of anthocyanin metabolic process
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42369)
+++ go_inferences.obo	(working copy)
@@ -61614,6 +61614,11 @@
 is_a: GO:0016337 {is_inferred="true"} ! single organismal cell-cell adhesion
 
 [Term]
+id: GO:0140040 ! mitochondrial polycistronic RNA processing
+is_a: GO:0031426 {is_inferred="true"} ! polycistronic mRNA processing
+is_a: GO:0090615 {is_inferred="true"} ! mitochondrial mRNA processing
+
+[Term]
 id: GO:1900000 ! regulation of anthocyanin catabolic process
 is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
 is_a: GO:0031537 {is_inferred="true"} ! regulation of anthocyanin metabolic process
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42353)
+++ go_inferences.obo	(working copy)
@@ -83582,7 +83582,7 @@
 is_a: GO:0070869 {is_inferred="true"} ! heterochromatin assembly involved in chromatin silencing
 
 [Term]
-id: GO:1904498 ! protein localization to actomyosin contractile ring involved in mitotic cytokinesis
+id: GO:1904498 ! protein localization to mitotic actomyosin contractile ring
 is_a: GO:1990179 {is_inferred="true"} ! protein localization to actomyosin contractile ring
 
 [Term]
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42325)
+++ go_inferences.obo	(working copy)
@@ -61514,6 +61514,62 @@
 is_a: GO:0120046 {is_inferred="true"} ! regulation of protein localization to medial cortical node
 
 [Term]
+id: GO:0120057 ! regulation of small intestinal transit
+is_a: GO:0044058 {is_inferred="true"} ! regulation of digestive system process
+
+[Term]
+id: GO:0120058 ! positive regulation of small intestinal transit
+is_a: GO:0060456 {is_inferred="true"} ! positive regulation of digestive system process
+is_a: GO:0120057 {is_inferred="true"} ! regulation of small intestinal transit
+
+[Term]
+id: GO:0120059 ! negative regulation of small intestinal transit
+is_a: GO:0060457 {is_inferred="true"} ! negative regulation of digestive system process
+is_a: GO:0120057 {is_inferred="true"} ! regulation of small intestinal transit
+
+[Term]
+id: GO:0120060 ! regulation of gastric emptying
+is_a: GO:1905333 {is_inferred="true"} ! regulation of gastric motility
+
+[Term]
+id: GO:0120061 ! negative regulation of gastric emptying
+is_a: GO:0060457 {is_inferred="true"} ! negative regulation of digestive system process
+is_a: GO:0120060 {is_inferred="true"} ! regulation of gastric emptying
+
+[Term]
+id: GO:0120062 ! positive regulation of gastric emptying
+is_a: GO:0060456 {is_inferred="true"} ! positive regulation of digestive system process
+is_a: GO:0120060 {is_inferred="true"} ! regulation of gastric emptying
+
+[Term]
+id: GO:0120068 ! regulation of stomach fundus smooth muscle contraction
+is_a: GO:1904304 {is_inferred="true"} ! regulation of gastro-intestinal system smooth muscle contraction
+
+[Term]
+id: GO:0120069 ! positive regulation of stomach fundus smooth muscle contraction
+is_a: GO:0120068 {is_inferred="true"} ! regulation of stomach fundus smooth muscle contraction
+is_a: GO:1904306 {is_inferred="true"} ! positive regulation of gastro-intestinal system smooth muscle contraction
+
+[Term]
+id: GO:0120070 ! negative regulation of stomach fundus smooth muscle contraction
+is_a: GO:0120068 {is_inferred="true"} ! regulation of stomach fundus smooth muscle contraction
+is_a: GO:1904305 {is_inferred="true"} ! negative regulation of gastro-intestinal system smooth muscle contraction
+
+[Term]
+id: GO:0120071 ! regulation of pyloric antrum smooth muscle contraction
+is_a: GO:1904304 {is_inferred="true"} ! regulation of gastro-intestinal system smooth muscle contraction
+
+[Term]
+id: GO:0120072 ! positive regulation of pyloric antrum smooth muscle contraction
+is_a: GO:0120071 {is_inferred="true"} ! regulation of pyloric antrum smooth muscle contraction
+is_a: GO:1904306 {is_inferred="true"} ! positive regulation of gastro-intestinal system smooth muscle contraction
+
+[Term]
+id: GO:0120073 ! negative regulation of pyloric antrum smooth muscle contraction
+is_a: GO:0120071 {is_inferred="true"} ! regulation of pyloric antrum smooth muscle contraction
+is_a: GO:1904305 {is_inferred="true"} ! negative regulation of gastro-intestinal system smooth muscle contraction
+
+[Term]
 id: GO:0140009 ! L-aspartate import across plasma membrane
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 is_a: GO:0089712 {is_inferred="true"} ! L-aspartate transmembrane transport
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42298)
+++ go_inferences.obo	(working copy)
@@ -38863,6 +38863,7 @@
 id: GO:0046216 ! indole phytoalexin catabolic process
 is_a: GO:0042436 {is_inferred="true"} ! indole-containing compound catabolic process
 is_a: GO:0046217 {is_inferred="true"} ! indole phytoalexin metabolic process
+is_a: GO:0051410 {is_inferred="true"} ! detoxification of nitrogen compound
 
 [Term]
 id: GO:0046217 ! indole phytoalexin metabolic process
@@ -38903,6 +38904,7 @@
 id: GO:0046225 ! bacteriocin catabolic process
 is_a: GO:0030652 {is_inferred="true"} ! peptide antibiotic catabolic process
 is_a: GO:0046224 {is_inferred="true"} ! bacteriocin metabolic process
+is_a: GO:0051410 {is_inferred="true"} ! detoxification of nitrogen compound
 
 [Term]
 id: GO:0046226 ! coumarin catabolic process
@@ -98015,6 +98017,7 @@
 is_a: GO:0043171 {is_inferred="true"} ! peptide catabolic process
 is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
 is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
+is_a: GO:0051410 {is_inferred="true"} ! detoxification of nitrogen compound
 is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
 is_a: GO:2001308 {is_inferred="true"} ! gliotoxin metabolic process
 
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42294)
+++ go_inferences.obo	(working copy)
@@ -59109,6 +59109,11 @@
 is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
 
 [Term]
+id: GO:0098699 ! structural constituent of presynaptic actin cytoskeleton
+is_a: GO:0005200 {is_inferred="true"} ! structural constituent of cytoskeleton
+is_a: GO:0098918 {is_inferred="true"} ! structural constituent of synapse
+
+[Term]
 id: GO:0098700 ! neurotransmitter loading into synaptic vesicle
 is_a: GO:0006836 {is_inferred="true"} ! neurotransmitter transport
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
@@ -59551,6 +59556,7 @@
 
 [Term]
 id: GO:0098871 ! postsynaptic actin cytoskeleton
+is_a: GO:0015629 {is_inferred="true"} ! actin cytoskeleton
 is_a: GO:0099571 {is_inferred="true"} ! postsynaptic cytoskeleton
 
 [Term]
@@ -59981,6 +59987,7 @@
 [Term]
 id: GO:0098973 ! structural constituent of postsynaptic actin cytoskeleton
 is_a: GO:0005200 {is_inferred="true"} ! structural constituent of cytoskeleton
+is_a: GO:0098918 {is_inferred="true"} ! structural constituent of synapse
 
 [Term]
 id: GO:0098974 ! postsynaptic actin cytoskeleton organization
@@ -60493,6 +60500,26 @@
 is_a: GO:0099131 {is_inferred="true"} ! ATP hydrolysis coupled ion transmembrane transport
 
 [Term]
+id: GO:0099140 ! presynaptic actin cytoskeleton organization
+is_a: GO:0030036 {is_inferred="true"} ! actin cytoskeleton organization
+
+[Term]
+id: GO:0099143 ! presynaptic actin cytoskeleton
+is_a: GO:0015629 {is_inferred="true"} ! actin cytoskeleton
+is_a: GO:0099569 {is_inferred="true"} ! presynaptic cytoskeleton
+
+[Term]
+id: GO:0099145 ! regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane
+is_a: GO:0017157 {is_inferred="true"} ! regulation of exocytosis
+is_a: GO:0033157 {is_inferred="true"} ! regulation of intracellular protein transport
+is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
+is_a: GO:0065008 {is_inferred="true"} ! regulation of biological quality
+is_a: GO:1902473 {is_inferred="true"} ! regulation of protein localization to synapse
+is_a: GO:1902683 {is_inferred="true"} ! regulation of receptor localization to synapse
+is_a: GO:1904375 {is_inferred="true"} ! regulation of protein localization to cell periphery
+is_a: GO:1905475 {is_inferred="true"} ! regulation of protein localization to membrane
+
+[Term]
 id: GO:0099400 ! caveola neck
 is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
 
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 42292)
+++ go_inferences.obo	(working copy)
@@ -1469,6 +1469,7 @@
 [Term]
 id: GO:0001774 ! microglial cell activation
 is_a: GO:0042116 {is_inferred="true"} ! macrophage activation
+is_a: GO:0061900 {is_inferred="true"} ! glial cell activation
 
 [Term]
 id: GO:0001781 ! neutrophil apoptotic process
@@ -41125,6 +41126,10 @@
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 
 [Term]
+id: GO:0048143 ! astrocyte activation
+is_a: GO:0061900 {is_inferred="true"} ! glial cell activation
+
+[Term]
 id: GO:0048145 ! regulation of fibroblast proliferation
 is_a: GO:0042127 {is_inferred="true"} ! regulation of cell proliferation
 
@@ -49437,6 +49442,10 @@
 is_a: GO:0061888 {is_inferred="true"} ! regulation of astrocyte activation
 
 [Term]
+id: GO:0061900 ! glial cell activation
+is_a: GO:0001775 {is_inferred="true"} ! cell activation
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41936)
+++ go_inferences.obo	(working copy)
@@ -48114,8 +48114,8 @@
 is_a: GO:1902593 {is_inferred="true"} ! single-organism nuclear import
 
 [Term]
-id: GO:0061016 ! snRNA import into Cajal body
-is_a: GO:0051030 {is_inferred="true"} ! snRNA transport
+id: GO:0061016 ! snRNA localization to Cajal body
+is_a: GO:0090670 {is_inferred="true"} ! RNA localization to Cajal body
 
 [Term]
 id: GO:0061017 ! hepatoblast differentiation
@@ -57889,6 +57889,10 @@
 is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
 
 [Term]
+id: GO:0090670 ! RNA localization to Cajal body
+is_a: GO:0090685 {is_inferred="true"} ! RNA localization to nucleus
+
+[Term]
 id: GO:0090679 ! cell differentiation involved in phenotypic switching
 is_a: GO:0030154 {is_inferred="true"} ! cell differentiation
 
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41926)
+++ go_inferences.obo	(working copy)
@@ -6538,15 +6538,22 @@
 is_a: GO:0016071 {is_inferred="true"} ! mRNA metabolic process
 
 [Term]
+id: GO:0006404 ! RNA import into nucleus
+is_a: GO:0050658 {is_inferred="true"} ! RNA transport
+is_a: GO:0051170 {is_inferred="true"} ! nuclear import
+
+[Term]
 id: GO:0006406 ! mRNA export from nucleus
-is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
+is_a: GO:0006913 {is_inferred="true"} ! nucleocytoplasmic transport
 
 [Term]
 id: GO:0006407 ! rRNA export from nucleus
+is_a: GO:0006913 {is_inferred="true"} ! nucleocytoplasmic transport
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:0006409 ! tRNA export from nucleus
+is_a: GO:0006913 {is_inferred="true"} ! nucleocytoplasmic transport
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
@@ -6961,6 +6968,7 @@
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0017038 {is_inferred="true"} ! protein import
 is_a: GO:0034504 {is_inferred="true"} ! protein localization to nucleus
+is_a: GO:0051169 {is_inferred="true"} ! nuclear transport
 is_a: GO:0072594 {is_inferred="true"} ! establishment of protein localization to organelle
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
@@ -6970,7 +6978,7 @@
 
 [Term]
 id: GO:0006611 ! protein export from nucleus
-is_a: GO:0030581 {is_inferred="true"} ! symbiont intracellular protein transport in host
+is_a: GO:0006913 {is_inferred="true"} ! nucleocytoplasmic transport
 
 [Term]
 id: GO:0006612 ! protein targeting to membrane
@@ -7813,6 +7821,10 @@
 is_a: GO:0099024 {is_inferred="true"} ! plasma membrane invagination
 
 [Term]
+id: GO:0006913 ! nucleocytoplasmic transport
+is_a: GO:0051169 {is_inferred="true"} ! nuclear transport
+
+[Term]
 id: GO:0006921 ! cellular component disassembly involved in execution phase of apoptosis
 is_a: GO:0022411 {is_inferred="true"} ! cellular component disassembly
 
@@ -22802,7 +22814,7 @@
 
 [Term]
 id: GO:0032066 ! nucleolus to nucleoplasm transport
-is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
+is_a: GO:0051169 {is_inferred="true"} ! nuclear transport
 
 [Term]
 id: GO:0032068 ! Type IV site-specific deoxyribonuclease complex
@@ -29557,6 +29569,8 @@
 
 [Term]
 id: GO:0035719 ! tRNA import into nucleus
+is_a: GO:0006404 {is_inferred="true"} ! RNA import into nucleus
+is_a: GO:0051031 {is_inferred="true"} ! tRNA transport
 is_a: GO:1902593 {is_inferred="true"} ! single-organism nuclear import
 
 [Term]
@@ -34625,11 +34639,6 @@
 is_a: GO:0044468 {is_inferred="true"} ! envenomation resulting in modulation of blood coagulation in other organism
 
 [Term]
-id: GO:0044376 ! RNA polymerase II complex import to nucleus
-is_a: GO:0030581 {is_inferred="true"} ! symbiont intracellular protein transport in host
-is_a: GO:1902594 {is_inferred="true"} ! multi-organism nuclear import
-
-[Term]
 id: GO:0044379 ! protein localization to actin cortical patch
 is_a: GO:0072697 {is_inferred="true"} ! protein localization to cell cortex
 is_a: GO:1903119 {is_inferred="true"} ! protein localization to actin cytoskeleton
@@ -34898,6 +34907,7 @@
 [Term]
 id: GO:0044744 ! protein targeting to nucleus
 is_a: GO:0034504 {is_inferred="true"} ! protein localization to nucleus
+is_a: GO:0051169 {is_inferred="true"} ! nuclear transport
 is_a: GO:0072594 {is_inferred="true"} ! establishment of protein localization to organelle
 
 [Term]
@@ -40564,27 +40574,25 @@
 
 [Term]
 id: GO:0046822 ! regulation of nucleocytoplasmic transport
-is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
+is_a: GO:0032386 {is_inferred="true"} ! regulation of intracellular transport
 
 [Term]
 id: GO:0046823 ! negative regulation of nucleocytoplasmic transport
+is_a: GO:0032387 {is_inferred="true"} ! negative regulation of intracellular transport
 is_a: GO:0046822 {is_inferred="true"} ! regulation of nucleocytoplasmic transport
-is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
 
 [Term]
 id: GO:0046824 ! positive regulation of nucleocytoplasmic transport
+is_a: GO:0032388 {is_inferred="true"} ! positive regulation of intracellular transport
 is_a: GO:0046822 {is_inferred="true"} ! regulation of nucleocytoplasmic transport
-is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
 
 [Term]
 id: GO:0046825 ! regulation of protein export from nucleus
 is_a: GO:0033157 {is_inferred="true"} ! regulation of intracellular protein transport
-is_a: GO:0043903 {is_inferred="true"} ! regulation of symbiosis, encompassing mutualism through parasitism
 is_a: GO:0046822 {is_inferred="true"} ! regulation of nucleocytoplasmic transport
 
 [Term]
 id: GO:0046826 ! negative regulation of protein export from nucleus
-is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:0046823 {is_inferred="true"} ! negative regulation of nucleocytoplasmic transport
 is_a: GO:0046825 {is_inferred="true"} ! regulation of protein export from nucleus
 is_a: GO:0090317 {is_inferred="true"} ! negative regulation of intracellular protein transport
@@ -40591,7 +40599,6 @@
 
 [Term]
 id: GO:0046827 ! positive regulation of protein export from nucleus
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:0046824 {is_inferred="true"} ! positive regulation of nucleocytoplasmic transport
 is_a: GO:0046825 {is_inferred="true"} ! regulation of protein export from nucleus
 is_a: GO:0090316 {is_inferred="true"} ! positive regulation of intracellular protein transport
@@ -40599,35 +40606,29 @@
 [Term]
 id: GO:0046828 ! regulation of RNA import into nucleus
 is_a: GO:0032239 {is_inferred="true"} ! regulation of nucleobase-containing compound transport
-is_a: GO:0046822 {is_inferred="true"} ! regulation of nucleocytoplasmic transport
 
 [Term]
 id: GO:0046829 ! negative regulation of RNA import into nucleus
 is_a: GO:0032240 {is_inferred="true"} ! negative regulation of nucleobase-containing compound transport
-is_a: GO:0046823 {is_inferred="true"} ! negative regulation of nucleocytoplasmic transport
 is_a: GO:0046828 {is_inferred="true"} ! regulation of RNA import into nucleus
 
 [Term]
 id: GO:0046830 ! positive regulation of RNA import into nucleus
 is_a: GO:0032241 {is_inferred="true"} ! positive regulation of nucleobase-containing compound transport
-is_a: GO:0046824 {is_inferred="true"} ! positive regulation of nucleocytoplasmic transport
 is_a: GO:0046828 {is_inferred="true"} ! regulation of RNA import into nucleus
 
 [Term]
 id: GO:0046831 ! regulation of RNA export from nucleus
 is_a: GO:0032239 {is_inferred="true"} ! regulation of nucleobase-containing compound transport
-is_a: GO:0046822 {is_inferred="true"} ! regulation of nucleocytoplasmic transport
 
 [Term]
 id: GO:0046832 ! negative regulation of RNA export from nucleus
 is_a: GO:0032240 {is_inferred="true"} ! negative regulation of nucleobase-containing compound transport
-is_a: GO:0046823 {is_inferred="true"} ! negative regulation of nucleocytoplasmic transport
 is_a: GO:0046831 {is_inferred="true"} ! regulation of RNA export from nucleus
 
 [Term]
 id: GO:0046833 ! positive regulation of RNA export from nucleus
 is_a: GO:0032241 {is_inferred="true"} ! positive regulation of nucleobase-containing compound transport
-is_a: GO:0046824 {is_inferred="true"} ! positive regulation of nucleocytoplasmic transport
 is_a: GO:0046831 {is_inferred="true"} ! regulation of RNA export from nucleus
 
 [Term]
@@ -43437,7 +43438,15 @@
 is_a: GO:1901135 {is_inferred="true"} ! carbohydrate derivative metabolic process
 
 [Term]
+id: GO:0051168 ! nuclear export
+is_a: GO:0006810 {is_inferred="true"} ! transport
+
+[Term]
 id: GO:0051169 ! nuclear transport
+is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
+
+[Term]
+id: GO:0051170 ! nuclear import
 is_a: GO:0006810 {is_inferred="true"} ! transport
 
 [Term]
@@ -44254,20 +44263,17 @@
 
 [Term]
 id: GO:0051531 ! NFAT protein import into nucleus
-is_a: GO:0030581 {is_inferred="true"} ! symbiont intracellular protein transport in host
+is_a: GO:0006913 {is_inferred="true"} ! nucleocytoplasmic transport
 is_a: GO:1902593 {is_inferred="true"} ! single-organism nuclear import
-is_a: GO:1902594 {is_inferred="true"} ! multi-organism nuclear import
 
 [Term]
 id: GO:0051532 ! regulation of NFAT protein import into nucleus
 is_a: GO:0042990 {is_inferred="true"} ! regulation of transcription factor import into nucleus
-is_a: GO:0043903 {is_inferred="true"} ! regulation of symbiosis, encompassing mutualism through parasitism
 is_a: GO:0046822 {is_inferred="true"} ! regulation of nucleocytoplasmic transport
 
 [Term]
 id: GO:0051533 ! positive regulation of NFAT protein import into nucleus
 is_a: GO:0042993 {is_inferred="true"} ! positive regulation of transcription factor import into nucleus
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:0046824 {is_inferred="true"} ! positive regulation of nucleocytoplasmic transport
 is_a: GO:0051532 {is_inferred="true"} ! regulation of NFAT protein import into nucleus
 
@@ -44274,7 +44280,6 @@
 [Term]
 id: GO:0051534 ! negative regulation of NFAT protein import into nucleus
 is_a: GO:0042992 {is_inferred="true"} ! negative regulation of transcription factor import into nucleus
-is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:0046823 {is_inferred="true"} ! negative regulation of nucleocytoplasmic transport
 is_a: GO:0051532 {is_inferred="true"} ! regulation of NFAT protein import into nucleus
 
@@ -48104,9 +48109,15 @@
 
 [Term]
 id: GO:0061015 ! snRNA import into nucleus
+is_a: GO:0006404 {is_inferred="true"} ! RNA import into nucleus
+is_a: GO:0051030 {is_inferred="true"} ! snRNA transport
 is_a: GO:1902593 {is_inferred="true"} ! single-organism nuclear import
 
 [Term]
+id: GO:0061016 ! snRNA import into Cajal body
+is_a: GO:0051030 {is_inferred="true"} ! snRNA transport
+
+[Term]
 id: GO:0061017 ! hepatoblast differentiation
 is_a: GO:0030855 {is_inferred="true"} ! epithelial cell differentiation
 
@@ -51786,11 +51797,8 @@
 
 [Term]
 id: GO:0071167 ! ribonucleoprotein complex import into nucleus
-is_a: GO:0006404 {is_inferred="true"} ! RNA import into nucleus
 is_a: GO:0006606 {is_inferred="true"} ! protein import into nucleus
-is_a: GO:0030581 {is_inferred="true"} ! symbiont intracellular protein transport in host
-is_a: GO:1902593 {is_inferred="true"} ! single-organism nuclear import
-is_a: GO:1902594 {is_inferred="true"} ! multi-organism nuclear import
+is_a: GO:0050658 {is_inferred="true"} ! RNA transport
 
 [Term]
 id: GO:0071169 ! establishment of protein localization to chromatin
@@ -90844,10 +90852,9 @@
 [Term]
 id: GO:1990236 ! proteasome core complex import into nucleus
 is_a: GO:0006606 {is_inferred="true"} ! protein import into nucleus
-is_a: GO:0030581 {is_inferred="true"} ! symbiont intracellular protein transport in host
+is_a: GO:0006913 {is_inferred="true"} ! nucleocytoplasmic transport
 is_a: GO:0031503 {is_inferred="true"} ! protein complex localization
 is_a: GO:1902593 {is_inferred="true"} ! single-organism nuclear import
-is_a: GO:1902594 {is_inferred="true"} ! multi-organism nuclear import
 
 [Term]
 id: GO:1990237 ! sequestration of proteasome core complex in proteasome storage granule
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changes in entailments

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synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41900)
+++ go_inferences.obo	(working copy)
@@ -61215,6 +61215,11 @@
 is_a: GO:1904776 {is_inferred="true"} ! regulation of protein localization to cell cortex
 
 [Term]
+id: GO:0106012 ! positive regulation of protein localization to medial cortex
+is_a: GO:0106011 {is_inferred="true"} ! regulation of protein localization to medial cortex
+is_a: GO:1904778 {is_inferred="true"} ! positive regulation of protein localization to cell cortex
+
+[Term]
 id: GO:0106014 ! regulation of inflammatory response to wounding
 is_a: GO:0050727 {is_inferred="true"} ! regulation of inflammatory response
 is_a: GO:1903034 {is_inferred="true"} ! regulation of response to wounding
@@ -61450,6 +61455,15 @@
 is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
+id: GO:0120046 ! regulation of protein localization to medial cortical node
+is_a: GO:0106011 {is_inferred="true"} ! regulation of protein localization to medial cortex
+
+[Term]
+id: GO:0120047 ! positive regulation of protein localization to medial cortical node
+is_a: GO:0106012 {is_inferred="true"} ! positive regulation of protein localization to medial cortex
+is_a: GO:0120046 {is_inferred="true"} ! regulation of protein localization to medial cortical node
+
+[Term]
 id: GO:0140009 ! L-aspartate import across plasma membrane
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 is_a: GO:0089712 {is_inferred="true"} ! L-aspartate transmembrane transport
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41882)
+++ go_inferences.obo	(working copy)
@@ -8667,6 +8667,7 @@
 [Term]
 id: GO:0008333 ! endosome to lysosome transport
 is_a: GO:0007041 {is_inferred="true"} ! lysosomal transport
+is_a: GO:0016192 {is_inferred="true"} ! vesicle-mediated transport
 is_a: GO:0016197 {is_inferred="true"} ! endosomal transport
 
 [Term]
@@ -35592,6 +35593,8 @@
 
 [Term]
 id: GO:0045324 ! late endosome to vacuole transport
+is_a: GO:0007034 {is_inferred="true"} ! vacuolar transport
+is_a: GO:0016192 {is_inferred="true"} ! vesicle-mediated transport
 is_a: GO:0016197 {is_inferred="true"} ! endosomal transport
 
 [Term]
@@ -49217,6 +49220,10 @@
 is_a: GO:0090174 {is_inferred="true"} ! organelle membrane fusion
 
 [Term]
+id: GO:0061764 ! late endosome to lysosome transport via multivesicular body sorting pathway
+is_a: GO:0045324 {is_inferred="true"} ! late endosome to vacuole transport
+
+[Term]
 id: GO:0061768 ! magnesium:sodium antiporter activity
 is_a: GO:0015081 {is_inferred="true"} ! sodium ion transmembrane transporter activity
 
@@ -59802,7 +59809,6 @@
 [Term]
 id: GO:0098943 ! neurotransmitter receptor transport, postsynaptic endosome to lysosome
 is_a: GO:0008333 {is_inferred="true"} ! endosome to lysosome transport
-is_a: GO:0016192 {is_inferred="true"} ! vesicle-mediated transport
 is_a: GO:0061462 {is_inferred="true"} ! protein localization to lysosome
 is_a: GO:0072666 {is_inferred="true"} ! establishment of protein localization to vacuole
 is_a: GO:0099637 {is_inferred="true"} ! neurotransmitter receptor transport
@@ -75361,8 +75367,8 @@
 
 [Term]
 id: GO:1902774 ! late endosome to lysosome transport
-is_a: GO:0008333 {is_inferred="true"} ! endosome to lysosome transport
-is_a: GO:0045324 {is_inferred="true"} ! late endosome to vacuole transport
+is_a: GO:0007041 {is_inferred="true"} ! lysosomal transport
+is_a: GO:0016197 {is_inferred="true"} ! endosomal transport
 
 [Term]
 id: GO:1902775 ! mitochondrial large ribosomal subunit assembly
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41877)
+++ go_inferences.obo	(working copy)
@@ -49402,6 +49402,23 @@
 is_a: GO:0090394 {is_inferred="true"} ! negative regulation of excitatory postsynaptic potential
 
 [Term]
+id: GO:0061888 ! regulation of astrocyte activation
+is_a: GO:0048710 {is_inferred="true"} ! regulation of astrocyte differentiation
+is_a: GO:0050865 {is_inferred="true"} ! regulation of cell activation
+
+[Term]
+id: GO:0061889 ! negative regulation of astrocyte activation
+is_a: GO:0048712 {is_inferred="true"} ! negative regulation of astrocyte differentiation
+is_a: GO:0050866 {is_inferred="true"} ! negative regulation of cell activation
+is_a: GO:0061888 {is_inferred="true"} ! regulation of astrocyte activation
+
+[Term]
+id: GO:0061890 ! positive regulation of astrocyte activation
+is_a: GO:0048711 {is_inferred="true"} ! positive regulation of astrocyte differentiation
+is_a: GO:0050867 {is_inferred="true"} ! positive regulation of cell activation
+is_a: GO:0061888 {is_inferred="true"} ! regulation of astrocyte activation
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41875)
+++ go_inferences.obo	(working copy)
@@ -1281,9 +1281,10 @@
 is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 
 [Term]
-id: GO:0001407 ! glycerophosphodiester transport
+id: GO:0001407 ! glycerophosphodiester transmembrane transport
 is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015748 {is_inferred="true"} ! organophosphate ester transport
+is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
 id: GO:0001408 ! guanine nucleotide transport
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41816)
+++ go_inferences.obo	(working copy)
@@ -49387,6 +49387,20 @@
 is_a: GO:0072583 {is_inferred="true"} ! clathrin-dependent endocytosis
 
 [Term]
+id: GO:0061884 ! regulation of mini excitatory postsynaptic potential
+is_a: GO:0098815 {is_inferred="true"} ! modulation of excitatory postsynaptic potential
+
+[Term]
+id: GO:0061885 ! positive regulation of mini excitatory postsynaptic potential
+is_a: GO:0061884 {is_inferred="true"} ! regulation of mini excitatory postsynaptic potential
+is_a: GO:2000463 {is_inferred="true"} ! positive regulation of excitatory postsynaptic potential
+
+[Term]
+id: GO:0061886 ! negative regulation of mini excitatory postsynaptic potential
+is_a: GO:0061884 {is_inferred="true"} ! regulation of mini excitatory postsynaptic potential
+is_a: GO:0090394 {is_inferred="true"} ! negative regulation of excitatory postsynaptic potential
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41814)
+++ go_inferences.obo	(working copy)
@@ -49366,6 +49366,27 @@
 is_a: GO:0061873 {is_inferred="true"} ! regulation of hepatic stellate cell contraction
 
 [Term]
+id: GO:0061880 ! regulation of anterograde axonal transport of mitochondrion
+is_a: GO:1902513 {is_inferred="true"} ! regulation of organelle transport along microtubule
+
+[Term]
+id: GO:0061881 ! positive regulation of anterograde axonal transport of mitochondrion
+is_a: GO:0032388 {is_inferred="true"} ! positive regulation of intracellular transport
+is_a: GO:0051272 {is_inferred="true"} ! positive regulation of cellular component movement
+is_a: GO:0061880 {is_inferred="true"} ! regulation of anterograde axonal transport of mitochondrion
+
+[Term]
+id: GO:0061882 ! negative regulation of anterograde axonal transport of mitochondrion
+is_a: GO:0032387 {is_inferred="true"} ! negative regulation of intracellular transport
+is_a: GO:0051271 {is_inferred="true"} ! negative regulation of cellular component movement
+is_a: GO:0061880 {is_inferred="true"} ! regulation of anterograde axonal transport of mitochondrion
+
+[Term]
+id: GO:0061883 ! clathrin-dependent endocytosis involved in vitellogenesis
+is_a: GO:0022414 {is_inferred="true"} ! reproductive process
+is_a: GO:0072583 {is_inferred="true"} ! clathrin-dependent endocytosis
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41738)
+++ go_inferences.obo	(working copy)
@@ -7695,7 +7695,6 @@
 [Term]
 id: GO:0006851 ! mitochondrial calcium ion transmembrane transport
 is_a: GO:0070588 {is_inferred="true"} ! calcium ion transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:0006853 ! carnitine shuttle
@@ -19986,7 +19985,6 @@
 id: GO:0030150 ! protein import into mitochondrial matrix
 is_a: GO:0006839 {is_inferred="true"} ! mitochondrial transport
 is_a: GO:0072655 {is_inferred="true"} ! establishment of protein localization to mitochondrion
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:0030151 ! molybdenum ion binding
@@ -30434,6 +30432,7 @@
 is_a: GO:0006851 {is_inferred="true"} ! mitochondrial calcium ion transmembrane transport
 is_a: GO:0060401 {is_inferred="true"} ! cytosolic calcium ion transport
 is_a: GO:0070509 {is_inferred="true"} ! calcium ion import
+is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:0036502 ! Derlin-1-VIMP complex
@@ -32187,7 +32186,6 @@
 id: GO:0042776 ! mitochondrial ATP synthesis coupled proton transport
 is_a: GO:0015986 {is_inferred="true"} ! ATP synthesis coupled proton transport
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:0042780 ! tRNA 3'-end processing
@@ -35112,7 +35110,6 @@
 
 [Term]
 id: GO:0045039 ! protein import into mitochondrial inner membrane
-is_a: GO:0006839 {is_inferred="true"} ! mitochondrial transport
 is_a: GO:0044743 {is_inferred="true"} ! protein transmembrane import into intracellular organelle
 is_a: GO:0090151 {is_inferred="true"} ! establishment of protein localization to mitochondrial membrane
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
@@ -35121,13 +35118,11 @@
 id: GO:0045040 ! protein import into mitochondrial outer membrane
 is_a: GO:0006839 {is_inferred="true"} ! mitochondrial transport
 is_a: GO:0090151 {is_inferred="true"} ! establishment of protein localization to mitochondrial membrane
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:0045041 ! protein import into mitochondrial intermembrane space
 is_a: GO:0006839 {is_inferred="true"} ! mitochondrial transport
 is_a: GO:0072655 {is_inferred="true"} ! establishment of protein localization to mitochondrion
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:0045046 ! protein import into peroxisome membrane
@@ -57451,7 +57446,6 @@
 [Term]
 id: GO:0090374 ! oligopeptide export from mitochondrion
 is_a: GO:0035672 {is_inferred="true"} ! oligopeptide transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:0090379 ! secondary cell wall biogenesis involved in seed trichome differentiation
@@ -61427,7 +61421,6 @@
 is_a: GO:0072530 {is_inferred="true"} ! purine-containing compound transmembrane transport
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 is_a: GO:1901679 {is_inferred="true"} ! nucleotide transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:0140025 ! contractile vacuole tethering involved in discharge
@@ -73457,7 +73450,6 @@
 id: GO:1902361 ! mitochondrial pyruvate transmembrane transport
 is_a: GO:0006850 {is_inferred="true"} ! mitochondrial pyruvate transport
 is_a: GO:1901475 {is_inferred="true"} ! pyruvate transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1902363 ! regulation of protein localization to spindle pole body
@@ -85594,7 +85586,6 @@
 is_a: GO:0015884 {is_inferred="true"} ! folic acid transport
 is_a: GO:0035461 {is_inferred="true"} ! vitamin transmembrane transport
 is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1904948 ! midbrain dopaminergic neuron differentiation
@@ -85768,7 +85759,6 @@
 is_a: GO:0015816 {is_inferred="true"} ! glycine transport
 is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1904984 ! regulation of quinolinate biosynthetic process
@@ -89355,7 +89345,6 @@
 [Term]
 id: GO:1905743 ! mitochondrial calcium uptake involved in negative regulation of presynaptic cytosolic calcium concentration
 is_a: GO:0036444 {is_inferred="true"} ! mitochondrial calcium uptake
-is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
 
 [Term]
 id: GO:1905744 ! regulation of mRNA cis splicing, via spliceosome
@@ -91038,6 +91027,7 @@
 is_a: GO:0006864 {is_inferred="true"} ! pyrimidine nucleotide transport
 is_a: GO:0072531 {is_inferred="true"} ! pyrimidine-containing compound transmembrane transport
 is_a: GO:1901679 {is_inferred="true"} ! nucleotide transmembrane transport
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
@@ -91070,7 +91060,6 @@
 [Term]
 id: GO:1990540 ! mitochondrial manganese ion transmembrane transport
 is_a: GO:0071421 {is_inferred="true"} ! manganese ion transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990541 ! mitochondrial citrate transmembrane transport
@@ -91084,7 +91073,6 @@
 [Term]
 id: GO:1990543 ! mitochondrial S-adenosyl-L-methionine transmembrane transport
 is_a: GO:1901962 {is_inferred="true"} ! S-adenosyl-L-methionine transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990544 ! mitochondrial ATP transmembrane transport
@@ -91092,7 +91080,6 @@
 is_a: GO:0072530 {is_inferred="true"} ! purine-containing compound transmembrane transport
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 is_a: GO:1901679 {is_inferred="true"} ! nucleotide transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990545 ! mitochondrial thiamine pyrophosphate transmembrane transport
@@ -91100,74 +91087,60 @@
 is_a: GO:0072531 {is_inferred="true"} ! pyrimidine-containing compound transmembrane transport
 is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990546 ! mitochondrial tricarboxylic acid transmembrane transport
 is_a: GO:0035674 {is_inferred="true"} ! tricarboxylic acid transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990547 ! mitochondrial phosphate ion transmembrane transport
 is_a: GO:0035435 {is_inferred="true"} ! phosphate ion transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990548 ! mitochondrial FAD transmembrane transport
 is_a: GO:0035350 {is_inferred="true"} ! FAD transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990549 ! mitochondrial NAD transmembrane transport
 is_a: GO:0035352 {is_inferred="true"} ! NAD transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990550 ! mitochondrial alpha-ketoglutarate transmembrane transport
 is_a: GO:0015742 {is_inferred="true"} ! alpha-ketoglutarate transport
 is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990551 ! mitochondrial 2-oxoadipate transmembrane transport
 is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
 is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990553 ! mitochondrial 5'-adenylyl sulfate transmembrane transport
 is_a: GO:1902558 {is_inferred="true"} ! 5'-adenylyl sulfate transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990554 ! mitochondrial 3'-phospho-5'-adenylyl sulfate transmembrane transport
 is_a: GO:1902559 {is_inferred="true"} ! 3'-phospho-5'-adenylyl sulfate transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990555 ! mitochondrial oxaloacetate transmembrane transport
 is_a: GO:1902356 {is_inferred="true"} ! oxaloacetate(2-) transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990556 ! mitochondrial isopropylmalate transmembrane transport
 is_a: GO:1902357 {is_inferred="true"} ! 2-isopropylmalate(2-) transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990557 ! mitochondrial sulfate transmembrane transport
 is_a: GO:1902358 {is_inferred="true"} ! sulfate transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990558 ! mitochondrial malonate(1-) transmembrane transport
 is_a: GO:1901553 {is_inferred="true"} ! malonic acid transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990559 ! mitochondrial coenzyme A transmembrane transport
 is_a: GO:0035349 {is_inferred="true"} ! coenzyme A transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990563 ! extracellular exosome complex
@@ -91197,7 +91170,6 @@
 id: GO:1990575 ! mitochondrial L-ornithine transmembrane transport
 is_a: GO:0000066 {is_inferred="true"} ! mitochondrial ornithine transport
 is_a: GO:1903352 {is_inferred="true"} ! L-ornithine transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990578 ! perinuclear endoplasmic reticulum membrane
@@ -91247,7 +91219,6 @@
 id: GO:1990614 ! mitochondrial magnesium ion transmembrane transport
 is_a: GO:0045016 {is_inferred="true"} ! mitochondrial magnesium ion transport
 is_a: GO:1903830 {is_inferred="true"} ! magnesium ion transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990616 ! magnesium ion export from mitochondrion
@@ -91545,7 +91516,6 @@
 id: GO:1990925 ! mitochondrial iron ion transmembrane transport
 is_a: GO:0034755 {is_inferred="true"} ! iron ion transmembrane transport
 is_a: GO:0048250 {is_inferred="true"} ! mitochondrial iron ion transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990953 ! intramanchette transport
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41722)
+++ go_inferences.obo	(working copy)
@@ -61250,6 +61250,10 @@
 is_a: GO:1903020 {is_inferred="true"} ! positive regulation of glycoprotein metabolic process
 
 [Term]
+id: GO:0110016 ! B-WICH complex
+is_a: GO:0044452 {is_inferred="true"} ! nucleolar part
+
+[Term]
 id: GO:0120006 ! regulation of glutamatergic neuron differentiation
 is_a: GO:0045664 {is_inferred="true"} ! regulation of neuron differentiation
 
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41661)
+++ go_inferences.obo	(working copy)
@@ -61193,6 +61193,20 @@
 is_a: GO:0106020 {is_inferred="true"} ! regulation of vesicle docking
 
 [Term]
+id: GO:0106023 ! regulation of pupariation
+is_a: GO:0048580 {is_inferred="true"} ! regulation of post-embryonic development
+
+[Term]
+id: GO:0106024 ! negative regulation of pupariation
+is_a: GO:0048581 {is_inferred="true"} ! negative regulation of post-embryonic development
+is_a: GO:0106023 {is_inferred="true"} ! regulation of pupariation
+
+[Term]
+id: GO:0106025 ! positive regulation of pupariation
+is_a: GO:0048582 {is_inferred="true"} ! positive regulation of post-embryonic development
+is_a: GO:0106023 {is_inferred="true"} ! regulation of pupariation
+
+[Term]
 id: GO:0110001 ! toxin-antitoxin complex
 is_a: GO:0005667 {is_inferred="true"} ! transcription factor complex
 is_a: GO:0017053 {is_inferred="true"} ! transcriptional repressor complex
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Index: go_inferences.obo
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--- go_inferences.obo	(revision 41652)
+++ go_inferences.obo	(working copy)
@@ -61420,6 +61420,10 @@
 is_a: GO:0009987 {is_inferred="true"} ! cellular process
 
 [Term]
+id: GO:0140039 ! cell-cell adhesion in response to extracellular stimulus
+is_a: GO:0016337 {is_inferred="true"} ! single organismal cell-cell adhesion
+
+[Term]
 id: GO:1900000 ! regulation of anthocyanin catabolic process
 is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
 is_a: GO:0031537 {is_inferred="true"} ! regulation of anthocyanin metabolic process
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41625)
+++ go_inferences.obo	(working copy)
@@ -42242,7 +42242,7 @@
 is_a: GO:0048524 {is_inferred="true"} ! positive regulation of viral process
 
 [Term]
-id: GO:0050435 ! beta-amyloid metabolic process
+id: GO:0050435 ! amyloid-beta metabolic process
 is_a: GO:0006518 {is_inferred="true"} ! peptide metabolic process
 
 [Term]
@@ -62470,18 +62470,18 @@
 is_a: GO:0071526 {is_inferred="true"} ! semaphorin-plexin signaling pathway
 
 [Term]
-id: GO:1900221 ! regulation of beta-amyloid clearance
+id: GO:1900221 ! regulation of amyloid-beta clearance
 is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
 
 [Term]
-id: GO:1900222 ! negative regulation of beta-amyloid clearance
+id: GO:1900222 ! negative regulation of amyloid-beta clearance
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-is_a: GO:1900221 {is_inferred="true"} ! regulation of beta-amyloid clearance
+is_a: GO:1900221 {is_inferred="true"} ! regulation of amyloid-beta clearance
 
 [Term]
-id: GO:1900223 ! positive regulation of beta-amyloid clearance
+id: GO:1900223 ! positive regulation of amyloid-beta clearance
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-is_a: GO:1900221 {is_inferred="true"} ! regulation of beta-amyloid clearance
+is_a: GO:1900221 {is_inferred="true"} ! regulation of amyloid-beta clearance
 
 [Term]
 id: GO:1900224 ! positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
@@ -71662,14 +71662,14 @@
 is_a: GO:0006468 {is_inferred="true"} ! protein phosphorylation
 
 [Term]
-id: GO:1902003 ! regulation of beta-amyloid formation
+id: GO:1902003 ! regulation of amyloid-beta formation
 is_a: GO:0034248 {is_inferred="true"} ! regulation of cellular amide metabolic process
 is_a: GO:1902991 {is_inferred="true"} ! regulation of amyloid precursor protein catabolic process
 
 [Term]
-id: GO:1902004 ! positive regulation of beta-amyloid formation
+id: GO:1902004 ! positive regulation of amyloid-beta formation
 is_a: GO:0034250 {is_inferred="true"} ! positive regulation of cellular amide metabolic process
-is_a: GO:1902003 {is_inferred="true"} ! regulation of beta-amyloid formation
+is_a: GO:1902003 {is_inferred="true"} ! regulation of amyloid-beta formation
 is_a: GO:1902993 {is_inferred="true"} ! positive regulation of amyloid precursor protein catabolic process
 
 [Term]
@@ -73764,9 +73764,9 @@
 is_a: GO:1902427 {is_inferred="true"} ! regulation of water channel activity
 
 [Term]
-id: GO:1902430 ! negative regulation of beta-amyloid formation
+id: GO:1902430 ! negative regulation of amyloid-beta formation
 is_a: GO:0034249 {is_inferred="true"} ! negative regulation of cellular amide metabolic process
-is_a: GO:1902003 {is_inferred="true"} ! regulation of beta-amyloid formation
+is_a: GO:1902003 {is_inferred="true"} ! regulation of amyloid-beta formation
 is_a: GO:1902992 {is_inferred="true"} ! negative regulation of amyloid precursor protein catabolic process
 
 [Term]
@@ -84105,13 +84105,13 @@
 is_a: GO:1904643 {is_inferred="true"} ! response to curcumin
 
 [Term]
-id: GO:1904645 ! response to beta-amyloid
+id: GO:1904645 ! response to amyloid-beta
 is_a: GO:1901652 {is_inferred="true"} ! response to peptide
 
 [Term]
-id: GO:1904646 ! cellular response to beta-amyloid
+id: GO:1904646 ! cellular response to amyloid-beta
 is_a: GO:1901653 {is_inferred="true"} ! cellular response to peptide
-is_a: GO:1904645 {is_inferred="true"} ! response to beta-amyloid
+is_a: GO:1904645 {is_inferred="true"} ! response to amyloid-beta
 
 [Term]
 id: GO:1904647 ! response to rotenone
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41469)
+++ go_inferences.obo	(working copy)
@@ -6537,11 +6537,11 @@
 is_a: GO:0016071 {is_inferred="true"} ! mRNA metabolic process
 
 [Term]
-id: GO:0006407 ! rRNA export from nucleus
-is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
+id: GO:0006406 ! mRNA export from nucleus
+is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
 
 [Term]
-id: GO:0006408 ! snRNA export from nucleus
+id: GO:0006407 ! rRNA export from nucleus
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
@@ -6961,7 +6961,7 @@
 is_a: GO:0017038 {is_inferred="true"} ! protein import
 is_a: GO:0034504 {is_inferred="true"} ! protein localization to nucleus
 is_a: GO:0072594 {is_inferred="true"} ! establishment of protein localization to organelle
-is_a: GO:1902593 {is_inferred="true"} ! single-organism nuclear import
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:0006608 ! snRNP protein import into nucleus
@@ -6968,6 +6968,10 @@
 is_a: GO:0071167 {is_inferred="true"} ! ribonucleoprotein complex import into nucleus
 
 [Term]
+id: GO:0006611 ! protein export from nucleus
+is_a: GO:0030581 {is_inferred="true"} ! symbiont intracellular protein transport in host
+
+[Term]
 id: GO:0006612 ! protein targeting to membrane
 is_a: GO:0006605 {is_inferred="true"} ! protein targeting
 is_a: GO:0090150 {is_inferred="true"} ! establishment of protein localization to membrane
@@ -22798,7 +22802,7 @@
 
 [Term]
 id: GO:0032066 ! nucleolus to nucleoplasm transport
-is_a: GO:0051169 {is_inferred="true"} ! nuclear transport
+is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
 
 [Term]
 id: GO:0032068 ! Type IV site-specific deoxyribonuclease complex
@@ -31241,7 +31245,6 @@
 
 [Term]
 id: GO:0042306 ! regulation of protein import into nucleus
-is_a: GO:0046822 {is_inferred="true"} ! regulation of nucleocytoplasmic transport
 is_a: GO:1900180 {is_inferred="true"} ! regulation of protein localization to nucleus
 is_a: GO:1903533 {is_inferred="true"} ! regulation of protein targeting
 is_a: GO:1904589 {is_inferred="true"} ! regulation of protein import
@@ -31249,7 +31252,6 @@
 [Term]
 id: GO:0042307 ! positive regulation of protein import into nucleus
 is_a: GO:0042306 {is_inferred="true"} ! regulation of protein import into nucleus
-is_a: GO:0046824 {is_inferred="true"} ! positive regulation of nucleocytoplasmic transport
 is_a: GO:0090316 {is_inferred="true"} ! positive regulation of intracellular protein transport
 is_a: GO:1900182 {is_inferred="true"} ! positive regulation of protein localization to nucleus
 is_a: GO:1904591 {is_inferred="true"} ! positive regulation of protein import
@@ -31257,7 +31259,6 @@
 [Term]
 id: GO:0042308 ! negative regulation of protein import into nucleus
 is_a: GO:0042306 {is_inferred="true"} ! regulation of protein import into nucleus
-is_a: GO:0046823 {is_inferred="true"} ! negative regulation of nucleocytoplasmic transport
 is_a: GO:0090317 {is_inferred="true"} ! negative regulation of intracellular protein transport
 is_a: GO:1900181 {is_inferred="true"} ! negative regulation of protein localization to nucleus
 is_a: GO:1904590 {is_inferred="true"} ! negative regulation of protein import
@@ -34624,6 +34625,11 @@
 is_a: GO:0044468 {is_inferred="true"} ! envenomation resulting in modulation of blood coagulation in other organism
 
 [Term]
+id: GO:0044376 ! RNA polymerase II complex import to nucleus
+is_a: GO:0030581 {is_inferred="true"} ! symbiont intracellular protein transport in host
+is_a: GO:1902594 {is_inferred="true"} ! multi-organism nuclear import
+
+[Term]
 id: GO:0044379 ! protein localization to actin cortical patch
 is_a: GO:0072697 {is_inferred="true"} ! protein localization to cell cortex
 is_a: GO:1903119 {is_inferred="true"} ! protein localization to actin cytoskeleton
@@ -34892,7 +34898,6 @@
 [Term]
 id: GO:0044744 ! protein targeting to nucleus
 is_a: GO:0034504 {is_inferred="true"} ! protein localization to nucleus
-is_a: GO:0051169 {is_inferred="true"} ! nuclear transport
 is_a: GO:0072594 {is_inferred="true"} ! establishment of protein localization to organelle
 
 [Term]
@@ -40520,7 +40525,6 @@
 [Term]
 id: GO:0046752 ! viral capsid precursor transport to host cell nucleus
 is_a: GO:0030581 {is_inferred="true"} ! symbiont intracellular protein transport in host
-is_a: GO:0075733 {is_inferred="true"} ! intracellular transport of virus
 
 [Term]
 id: GO:0046760 ! viral budding from Golgi membrane
@@ -40561,25 +40565,27 @@
 
 [Term]
 id: GO:0046822 ! regulation of nucleocytoplasmic transport
-is_a: GO:0032386 {is_inferred="true"} ! regulation of intracellular transport
+is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
 
 [Term]
 id: GO:0046823 ! negative regulation of nucleocytoplasmic transport
-is_a: GO:0032387 {is_inferred="true"} ! negative regulation of intracellular transport
 is_a: GO:0046822 {is_inferred="true"} ! regulation of nucleocytoplasmic transport
+is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
 
 [Term]
 id: GO:0046824 ! positive regulation of nucleocytoplasmic transport
-is_a: GO:0032388 {is_inferred="true"} ! positive regulation of intracellular transport
 is_a: GO:0046822 {is_inferred="true"} ! regulation of nucleocytoplasmic transport
+is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
 
 [Term]
 id: GO:0046825 ! regulation of protein export from nucleus
 is_a: GO:0033157 {is_inferred="true"} ! regulation of intracellular protein transport
+is_a: GO:0043903 {is_inferred="true"} ! regulation of symbiosis, encompassing mutualism through parasitism
 is_a: GO:0046822 {is_inferred="true"} ! regulation of nucleocytoplasmic transport
 
 [Term]
 id: GO:0046826 ! negative regulation of protein export from nucleus
+is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:0046823 {is_inferred="true"} ! negative regulation of nucleocytoplasmic transport
 is_a: GO:0046825 {is_inferred="true"} ! regulation of protein export from nucleus
 is_a: GO:0090317 {is_inferred="true"} ! negative regulation of intracellular protein transport
@@ -40586,6 +40592,7 @@
 
 [Term]
 id: GO:0046827 ! positive regulation of protein export from nucleus
+is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:0046824 {is_inferred="true"} ! positive regulation of nucleocytoplasmic transport
 is_a: GO:0046825 {is_inferred="true"} ! regulation of protein export from nucleus
 is_a: GO:0090316 {is_inferred="true"} ! positive regulation of intracellular protein transport
@@ -43432,7 +43439,7 @@
 
 [Term]
 id: GO:0051169 ! nuclear transport
-is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
+is_a: GO:0006810 {is_inferred="true"} ! transport
 
 [Term]
 id: GO:0051174 ! regulation of phosphorus metabolic process
@@ -44247,17 +44254,29 @@
 is_a: GO:0051516 {is_inferred="true"} ! regulation of bipolar cell growth
 
 [Term]
+id: GO:0051531 ! NFAT protein import into nucleus
+is_a: GO:0030581 {is_inferred="true"} ! symbiont intracellular protein transport in host
+is_a: GO:1902593 {is_inferred="true"} ! single-organism nuclear import
+is_a: GO:1902594 {is_inferred="true"} ! multi-organism nuclear import
+
+[Term]
 id: GO:0051532 ! regulation of NFAT protein import into nucleus
 is_a: GO:0042990 {is_inferred="true"} ! regulation of transcription factor import into nucleus
+is_a: GO:0043903 {is_inferred="true"} ! regulation of symbiosis, encompassing mutualism through parasitism
+is_a: GO:0046822 {is_inferred="true"} ! regulation of nucleocytoplasmic transport
 
 [Term]
 id: GO:0051533 ! positive regulation of NFAT protein import into nucleus
 is_a: GO:0042993 {is_inferred="true"} ! positive regulation of transcription factor import into nucleus
+is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
+is_a: GO:0046824 {is_inferred="true"} ! positive regulation of nucleocytoplasmic transport
 is_a: GO:0051532 {is_inferred="true"} ! regulation of NFAT protein import into nucleus
 
 [Term]
 id: GO:0051534 ! negative regulation of NFAT protein import into nucleus
 is_a: GO:0042992 {is_inferred="true"} ! negative regulation of transcription factor import into nucleus
+is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
+is_a: GO:0046823 {is_inferred="true"} ! negative regulation of nucleocytoplasmic transport
 is_a: GO:0051532 {is_inferred="true"} ! regulation of NFAT protein import into nucleus
 
 [Term]
@@ -51714,6 +51733,9 @@
 id: GO:0071167 ! ribonucleoprotein complex import into nucleus
 is_a: GO:0006404 {is_inferred="true"} ! RNA import into nucleus
 is_a: GO:0006606 {is_inferred="true"} ! protein import into nucleus
+is_a: GO:0030581 {is_inferred="true"} ! symbiont intracellular protein transport in host
+is_a: GO:1902593 {is_inferred="true"} ! single-organism nuclear import
+is_a: GO:1902594 {is_inferred="true"} ! multi-organism nuclear import
 
 [Term]
 id: GO:0071169 ! establishment of protein localization to chromatin
@@ -55511,12 +55533,8 @@
 is_a: GO:1903665 {is_inferred="true"} ! negative regulation of asexual reproduction
 
 [Term]
-id: GO:0075521 ! microtubule-dependent intracellular transport of viral material towards nucleus
-is_a: GO:0051169 {is_inferred="true"} ! nuclear transport
-
-[Term]
 id: GO:0075733 ! intracellular transport of virus
-is_a: GO:1902583 {is_inferred="true"} ! multi-organism intracellular transport
+is_a: GO:0046794 {is_inferred="true"} ! transport of virus
 
 [Term]
 id: GO:0080003 ! thalianol metabolic process
@@ -67903,18 +67921,18 @@
 
 [Term]
 id: GO:1901252 ! regulation of intracellular transport of viral material
-is_a: GO:0032386 {is_inferred="true"} ! regulation of intracellular transport
+is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
 is_a: GO:1903900 {is_inferred="true"} ! regulation of viral life cycle
 
 [Term]
 id: GO:1901253 ! negative regulation of intracellular transport of viral material
-is_a: GO:0032387 {is_inferred="true"} ! negative regulation of intracellular transport
+is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
 is_a: GO:1901252 {is_inferred="true"} ! regulation of intracellular transport of viral material
 is_a: GO:1903901 {is_inferred="true"} ! negative regulation of viral life cycle
 
 [Term]
 id: GO:1901254 ! positive regulation of intracellular transport of viral material
-is_a: GO:0032388 {is_inferred="true"} ! positive regulation of intracellular transport
+is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
 is_a: GO:1901252 {is_inferred="true"} ! regulation of intracellular transport of viral material
 is_a: GO:1903902 {is_inferred="true"} ! positive regulation of viral life cycle
 
@@ -74447,13 +74465,13 @@
 
 [Term]
 id: GO:1902593 ! single-organism nuclear import
+is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
 is_a: GO:0051170 {is_inferred="true"} ! nuclear import
-is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:1902594 ! multi-organism nuclear import
+is_a: GO:0044766 {is_inferred="true"} ! multi-organism transport
 is_a: GO:0051170 {is_inferred="true"} ! nuclear import
-is_a: GO:1902583 {is_inferred="true"} ! multi-organism intracellular transport
 
 [Term]
 id: GO:1902595 ! regulation of DNA replication origin binding
@@ -90742,7 +90760,10 @@
 [Term]
 id: GO:1990236 ! proteasome core complex import into nucleus
 is_a: GO:0006606 {is_inferred="true"} ! protein import into nucleus
+is_a: GO:0030581 {is_inferred="true"} ! symbiont intracellular protein transport in host
 is_a: GO:0031503 {is_inferred="true"} ! protein complex localization
+is_a: GO:1902593 {is_inferred="true"} ! single-organism nuclear import
+is_a: GO:1902594 {is_inferred="true"} ! multi-organism nuclear import
 
 [Term]
 id: GO:1990237 ! sequestration of proteasome core complex in proteasome storage granule
------------------------------------------------------------------------
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changes in entailments

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changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41460)
+++ go_inferences.obo	(working copy)
@@ -28616,6 +28616,11 @@
 is_a: GO:0030575 {is_inferred="true"} ! nuclear body organization
 
 [Term]
+id: GO:0035064 ! methylated histone binding
+is_a: GO:0042393 {is_inferred="true"} ! histone binding
+is_a: GO:0140034 {is_inferred="true"} ! methylation-dependent protein binding
+
+[Term]
 id: GO:0035065 ! regulation of histone acetylation
 is_a: GO:0031056 {is_inferred="true"} ! regulation of histone modification
 is_a: GO:2000756 {is_inferred="true"} ! regulation of peptidyl-lysine acetylation
@@ -49063,6 +49068,11 @@
 is_a: GO:0071168 {is_inferred="true"} ! protein localization to chromatin
 
 [Term]
+id: GO:0061649 ! ubiquitin modification-dependent histone binding
+is_a: GO:0042393 {is_inferred="true"} ! histone binding
+is_a: GO:0140036 {is_inferred="true"} ! ubiquitin-dependent protein binding
+
+[Term]
 id: GO:0061672 ! glutathione hydrolase complex
 is_a: GO:1905368 {is_inferred="true"} ! peptidase complex
 
@@ -50435,6 +50445,11 @@
 is_a: GO:0098662 {is_inferred="true"} ! inorganic cation transmembrane transport
 
 [Term]
+id: GO:0070577 ! lysine-acetylated histone binding
+is_a: GO:0042393 {is_inferred="true"} ! histone binding
+is_a: GO:0140033 {is_inferred="true"} ! acetylation-dependent protein binding
+
+[Term]
 id: GO:0070578 ! RISC-loading complex
 is_a: GO:1902555 {is_inferred="true"} ! endoribonuclease complex
 
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41423)
+++ go_inferences.obo	(working copy)
@@ -25899,7 +25899,7 @@
 
 [Term]
 id: GO:0033162 ! melanosome membrane
-is_a: GO:0098588 {is_inferred="true"} ! bounding membrane of organelle
+is_a: GO:0090741 {is_inferred="true"} ! pigment granule membrane
 is_a: GO:0098805 {is_inferred="true"} ! whole membrane
 
 [Term]
@@ -57822,6 +57822,15 @@
 is_a: GO:0044420 {is_inferred="true"} ! extracellular matrix component
 
 [Term]
+id: GO:0090740 ! integral component of pigment granule membrane
+is_a: GO:0031301 {is_inferred="true"} ! integral component of organelle membrane
+is_a: GO:0044433 {is_inferred="true"} ! cytoplasmic vesicle part
+
+[Term]
+id: GO:0090741 ! pigment granule membrane
+is_a: GO:0044433 {is_inferred="true"} ! cytoplasmic vesicle part
+
+[Term]
 id: GO:0093001 ! glycolysis from storage polysaccharide through glucose-1-phosphate
 is_a: GO:0000272 {is_inferred="true"} ! polysaccharide catabolic process
 is_a: GO:0061622 {is_inferred="true"} ! glycolytic process through glucose-1-phosphate
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41413)
+++ go_inferences.obo	(working copy)
@@ -1749,6 +1749,7 @@
 id: GO:0001928 ! regulation of exocyst assembly
 is_a: GO:0017157 {is_inferred="true"} ! regulation of exocytosis
 is_a: GO:0043254 {is_inferred="true"} ! regulation of protein complex assembly
+is_a: GO:0106020 {is_inferred="true"} ! regulation of vesicle docking
 
 [Term]
 id: GO:0001929 ! negative regulation of exocyst assembly
@@ -1755,6 +1756,7 @@
 is_a: GO:0001928 {is_inferred="true"} ! regulation of exocyst assembly
 is_a: GO:0031333 {is_inferred="true"} ! negative regulation of protein complex assembly
 is_a: GO:0045920 {is_inferred="true"} ! negative regulation of exocytosis
+is_a: GO:0106021 {is_inferred="true"} ! negative regulation of vesicle docking
 
 [Term]
 id: GO:0001930 ! positive regulation of exocyst assembly
@@ -1761,6 +1763,7 @@
 is_a: GO:0001928 {is_inferred="true"} ! regulation of exocyst assembly
 is_a: GO:0031334 {is_inferred="true"} ! positive regulation of protein complex assembly
 is_a: GO:0045921 {is_inferred="true"} ! positive regulation of exocytosis
+is_a: GO:0106022 {is_inferred="true"} ! positive regulation of vesicle docking
 
 [Term]
 id: GO:0001931 ! uropod
@@ -61132,6 +61135,22 @@
 is_a: GO:1903036 {is_inferred="true"} ! positive regulation of response to wounding
 
 [Term]
+id: GO:0106020 ! regulation of vesicle docking
+is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
+
+[Term]
+id: GO:0106021 ! negative regulation of vesicle docking
+is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
+is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
+is_a: GO:0106020 {is_inferred="true"} ! regulation of vesicle docking
+
+[Term]
+id: GO:0106022 ! positive regulation of vesicle docking
+is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
+is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
+is_a: GO:0106020 {is_inferred="true"} ! regulation of vesicle docking
+
+[Term]
 id: GO:0110001 ! toxin-antitoxin complex
 is_a: GO:0005667 {is_inferred="true"} ! transcription factor complex
 is_a: GO:0017053 {is_inferred="true"} ! transcriptional repressor complex
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41391)
+++ go_inferences.obo	(working copy)
@@ -61306,6 +61306,18 @@
 is_a: GO:0120040 {is_inferred="true"} ! regulation of macrophage proliferation
 
 [Term]
+id: GO:0120043 ! stereocilium shaft
+is_a: GO:0044422 {is_inferred="true"} ! organelle part
+is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
+
+[Term]
+id: GO:0120044 ! stereocilium base
+is_a: GO:0044422 {is_inferred="true"} ! organelle part
+is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
+
+[Term]
 id: GO:0140009 ! L-aspartate import across plasma membrane
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 is_a: GO:0089712 {is_inferred="true"} ! L-aspartate transmembrane transport
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41384)
+++ go_inferences.obo	(working copy)
@@ -1742,6 +1742,10 @@
 is_a: GO:0045579 {is_inferred="true"} ! positive regulation of B cell differentiation
 
 [Term]
+id: GO:0001927 ! exocyst assembly
+is_a: GO:0140029 {is_inferred="true"} ! exocytic process
+
+[Term]
 id: GO:0001928 ! regulation of exocyst assembly
 is_a: GO:0017157 {is_inferred="true"} ! regulation of exocytosis
 is_a: GO:0043254 {is_inferred="true"} ! regulation of protein complex assembly
@@ -2496,13 +2500,31 @@
 
 [Term]
 id: GO:0002552 ! serotonin secretion by mast cell
+is_a: GO:0140029 {is_inferred="true"} ! exocytic process
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:0002553 ! histamine secretion by mast cell
+is_a: GO:0140029 {is_inferred="true"} ! exocytic process
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
+id: GO:0002554 ! serotonin secretion by platelet
+is_a: GO:0140029 {is_inferred="true"} ! exocytic process
+
+[Term]
+id: GO:0002555 ! histamine secretion by platelet
+is_a: GO:0140029 {is_inferred="true"} ! exocytic process
+
+[Term]
+id: GO:0002556 ! serotonin secretion by basophil
+is_a: GO:0140029 {is_inferred="true"} ! exocytic process
+
+[Term]
+id: GO:0002557 ! histamine secretion by basophil
+is_a: GO:0140029 {is_inferred="true"} ! exocytic process
+
+[Term]
 id: GO:0002575 ! basophil chemotaxis
 is_a: GO:0071621 {is_inferred="true"} ! granulocyte chemotaxis
 
@@ -7773,6 +7795,7 @@
 [Term]
 id: GO:0006904 ! vesicle docking involved in exocytosis
 is_a: GO:0048278 {is_inferred="true"} ! vesicle docking
+is_a: GO:0140029 {is_inferred="true"} ! exocytic process
 
 [Term]
 id: GO:0006910 ! phagocytosis, recognition
@@ -16199,6 +16222,7 @@
 id: GO:0016080 ! synaptic vesicle targeting
 is_a: GO:0006903 {is_inferred="true"} ! vesicle targeting
 is_a: GO:0099531 {is_inferred="true"} ! presynaptic process involved in chemical synaptic transmission
+is_a: GO:0140029 {is_inferred="true"} ! exocytic process
 
 [Term]
 id: GO:0016081 ! synaptic vesicle docking
@@ -16207,6 +16231,7 @@
 [Term]
 id: GO:0016082 ! synaptic vesicle priming
 is_a: GO:0099531 {is_inferred="true"} ! presynaptic process involved in chemical synaptic transmission
+is_a: GO:0140029 {is_inferred="true"} ! exocytic process
 
 [Term]
 id: GO:0016090 ! prenol metabolic process
@@ -19676,6 +19701,10 @@
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
 
 [Term]
+id: GO:0022402 ! cell cycle process
+is_a: GO:0009987 {is_inferred="true"} ! cellular process
+
+[Term]
 id: GO:0022604 ! regulation of cell morphogenesis
 is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
 is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
@@ -49173,6 +49202,10 @@
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 
 [Term]
+id: GO:0061789 ! dense core granule priming
+is_a: GO:0140029 {is_inferred="true"} ! exocytic process
+
+[Term]
 id: GO:0061792 ! secretory granule maturation
 is_a: GO:0021700 {is_inferred="true"} ! developmental maturation
 is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
@@ -50358,6 +50391,10 @@
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
 [Term]
+id: GO:0070560 ! protein secretion by platelet
+is_a: GO:0140029 {is_inferred="true"} ! exocytic process
+
+[Term]
 id: GO:0070562 ! regulation of vitamin D receptor signaling pathway
 is_a: GO:0009966 {is_inferred="true"} ! regulation of signal transduction
 is_a: GO:0032107 {is_inferred="true"} ! regulation of response to nutrient levels
@@ -57679,6 +57716,7 @@
 [Term]
 id: GO:0090522 ! vesicle tethering involved in exocytosis
 is_a: GO:0099022 {is_inferred="true"} ! vesicle tethering
+is_a: GO:0140029 {is_inferred="true"} ! exocytic process
 
 [Term]
 id: GO:0090525 ! regulation of glycolysis involved in cellular glucose homeostasis
@@ -59381,6 +59419,7 @@
 [Term]
 id: GO:0098866 ! multivesicular body fusion to apical plasma membrane
 is_a: GO:0090174 {is_inferred="true"} ! organelle membrane fusion
+is_a: GO:0140029 {is_inferred="true"} ! exocytic process
 
 [Term]
 id: GO:0098867 ! intramembranous bone growth
@@ -59422,6 +59461,7 @@
 
 [Term]
 id: GO:0098881 ! exocytic insertion of neurotransmitter receptor to plasma membrane
+is_a: GO:0006887 {is_inferred="true"} ! exocytosis
 is_a: GO:0051668 {is_inferred="true"} ! localization within membrane
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
@@ -60338,6 +60378,10 @@
 is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
 
 [Term]
+id: GO:0099500 ! vesicle fusion to plasma membrane
+is_a: GO:0140029 {is_inferred="true"} ! exocytic process
+
+[Term]
 id: GO:0099501 ! exocytic vesicle membrane
 is_a: GO:0030658 {is_inferred="true"} ! transport vesicle membrane
 
@@ -61299,6 +61343,10 @@
 is_a: GO:0006903 {is_inferred="true"} ! vesicle targeting
 
 [Term]
+id: GO:0140029 ! exocytic process
+is_a: GO:0009987 {is_inferred="true"} ! cellular process
+
+[Term]
 id: GO:1900000 ! regulation of anthocyanin catabolic process
 is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
 is_a: GO:0031537 {is_inferred="true"} ! regulation of anthocyanin metabolic process
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41305)
+++ go_inferences.obo	(working copy)
@@ -7673,6 +7673,10 @@
 is_a: GO:1902001 {is_inferred="true"} ! fatty acid transmembrane transport
 
 [Term]
+id: GO:0006855 ! drug transmembrane transport
+is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
+
+[Term]
 id: GO:0006857 ! oligopeptide transport
 is_a: GO:0015833 {is_inferred="true"} ! peptide transport
 
@@ -13827,7 +13831,8 @@
 
 [Term]
 id: GO:0014808 ! release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
-is_a: GO:1903514 {is_inferred="true"} ! calcium ion transport from endoplasmic reticulum to cytosol
+is_a: GO:0070296 {is_inferred="true"} ! sarcoplasmic reticulum calcium ion transport
+is_a: GO:1903514 {is_inferred="true"} ! release of sequestered calcium ion into cytosol by endoplasmic reticulum
 
 [Term]
 id: GO:0014813 ! skeletal muscle satellite cell commitment
@@ -30000,12 +30005,12 @@
 [Term]
 id: GO:0036084 ! GDP-fucose import into endoplasmic reticulum lumen
 is_a: GO:0015783 {is_inferred="true"} ! GDP-fucose transport
-is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
+is_a: GO:0090480 {is_inferred="true"} ! purine nucleotide-sugar transmembrane transport
 
 [Term]
 id: GO:0036085 ! GDP-fucose import into Golgi lumen
 is_a: GO:0015783 {is_inferred="true"} ! GDP-fucose transport
-is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
+is_a: GO:0090480 {is_inferred="true"} ! purine nucleotide-sugar transmembrane transport
 
 [Term]
 id: GO:0036087 ! glutathione synthase complex
@@ -43490,6 +43495,14 @@
 is_a: GO:0043436 {is_inferred="true"} ! oxoacid metabolic process
 
 [Term]
+id: GO:0051208 ! sequestering of calcium ion
+is_a: GO:0051235 {is_inferred="true"} ! maintenance of location
+
+[Term]
+id: GO:0051209 ! release of sequestered calcium ion into cytosol
+is_a: GO:0097553 {is_inferred="true"} ! calcium ion transmembrane import into cytosol
+
+[Term]
 id: GO:0051212 ! vanadium ion binding
 is_a: GO:0046914 {is_inferred="true"} ! transition metal ion binding
 
@@ -43587,7 +43600,6 @@
 id: GO:0051279 ! regulation of release of sequestered calcium ion into cytosol
 is_a: GO:0010522 {is_inferred="true"} ! regulation of calcium ion transport into cytosol
 is_a: GO:0051282 {is_inferred="true"} ! regulation of sequestering of calcium ion
-is_a: GO:0090279 {is_inferred="true"} ! regulation of calcium ion import
 is_a: GO:1903169 {is_inferred="true"} ! regulation of calcium ion transmembrane transport
 
 [Term]
@@ -43596,7 +43608,6 @@
 is_a: GO:0051279 {is_inferred="true"} ! regulation of release of sequestered calcium ion into cytosol
 is_a: GO:0051283 {is_inferred="true"} ! negative regulation of sequestering of calcium ion
 is_a: GO:0051284 {is_inferred="true"} ! positive regulation of sequestering of calcium ion
-is_a: GO:0090281 {is_inferred="true"} ! negative regulation of calcium ion import
 is_a: GO:1903170 {is_inferred="true"} ! negative regulation of calcium ion transmembrane transport
 
 [Term]
@@ -43603,7 +43614,6 @@
 id: GO:0051281 ! positive regulation of release of sequestered calcium ion into cytosol
 is_a: GO:0010524 {is_inferred="true"} ! positive regulation of calcium ion transport into cytosol
 is_a: GO:0051279 {is_inferred="true"} ! regulation of release of sequestered calcium ion into cytosol
-is_a: GO:0090280 {is_inferred="true"} ! positive regulation of calcium ion import
 is_a: GO:1904427 {is_inferred="true"} ! positive regulation of calcium ion transmembrane transport
 
 [Term]
@@ -48810,9 +48820,9 @@
 is_a: GO:0060563 {is_inferred="true"} ! neuroepithelial cell differentiation
 
 [Term]
-id: GO:0061454 ! Golgi calcium ion export
+id: GO:0061454 ! release of sequestered calcium ion into cytosol by Golgi
+is_a: GO:0051209 {is_inferred="true"} ! release of sequestered calcium ion into cytosol
 is_a: GO:0061856 {is_inferred="true"} ! Golgi calcium ion transmembrane transport
-is_a: GO:1901660 {is_inferred="true"} ! calcium ion export
 
 [Term]
 id: GO:0061455 ! integral component of muscle cell projection membrane
@@ -54423,11 +54433,15 @@
 
 [Term]
 id: GO:0072530 ! purine-containing compound transmembrane transport
+is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
 is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
+is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
 id: GO:0072531 ! pyrimidine-containing compound transmembrane transport
+is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
 is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
+is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
 id: GO:0072536 ! interleukin-23 receptor complex
@@ -57584,6 +57598,11 @@
 is_a: GO:0090478 {is_inferred="true"} ! serine import
 
 [Term]
+id: GO:0090480 ! purine nucleotide-sugar transmembrane transport
+is_a: GO:0036079 {is_inferred="true"} ! purine nucleotide-sugar transport
+is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
+
+[Term]
 id: GO:0090494 ! dopamine uptake
 is_a: GO:0090493 {is_inferred="true"} ! catecholamine uptake
 
@@ -58337,6 +58356,11 @@
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
 [Term]
+id: GO:0097553 ! calcium ion transmembrane import into cytosol
+is_a: GO:0060402 {is_inferred="true"} ! calcium ion transport into cytosol
+is_a: GO:0070588 {is_inferred="true"} ! calcium ion transmembrane transport
+
+[Term]
 id: GO:0097576 ! vacuole fusion
 is_a: GO:0048284 {is_inferred="true"} ! organelle fusion
 
@@ -58946,6 +58970,7 @@
 id: GO:0098703 ! calcium ion import across plasma membrane
 is_a: GO:0097553 {is_inferred="true"} ! calcium ion transmembrane import into cytosol
 is_a: GO:0098659 {is_inferred="true"} ! inorganic cation import across plasma membrane
+is_a: GO:1902656 {is_inferred="true"} ! calcium ion import into cytosol
 
 [Term]
 id: GO:0098704 ! carbohydrate import across plasma membrane
@@ -58971,6 +58996,7 @@
 
 [Term]
 id: GO:0098708 ! glucose import across plasma membrane
+is_a: GO:0098704 {is_inferred="true"} ! carbohydrate import across plasma membrane
 is_a: GO:1904659 {is_inferred="true"} ! glucose transmembrane transport
 
 [Term]
@@ -60160,7 +60186,7 @@
 [Term]
 id: GO:0099093 ! mitochondrial calcium release
 is_a: GO:0006851 {is_inferred="true"} ! mitochondrial calcium ion transmembrane transport
-is_a: GO:0097553 {is_inferred="true"} ! calcium ion transmembrane import into cytosol
+is_a: GO:0051209 {is_inferred="true"} ! release of sequestered calcium ion into cytosol
 is_a: GO:1901660 {is_inferred="true"} ! calcium ion export
 
 [Term]
@@ -60520,6 +60546,7 @@
 
 [Term]
 id: GO:0099585 ! release of sequestered calcium ion into presynaptic cytosol
+is_a: GO:0051209 {is_inferred="true"} ! release of sequestered calcium ion into cytosol
 is_a: GO:0099533 {is_inferred="true"} ! positive regulation of presynaptic cytosolic calcium concentration
 
 [Term]
@@ -78530,12 +78557,13 @@
 is_a: GO:0097089 {is_inferred="true"} ! methyl-branched fatty acid metabolic process
 
 [Term]
-id: GO:1903514 ! calcium ion transport from endoplasmic reticulum to cytosol
-is_a: GO:0060402 {is_inferred="true"} ! calcium ion transport into cytosol
+id: GO:1903514 ! release of sequestered calcium ion into cytosol by endoplasmic reticulum
+is_a: GO:0051209 {is_inferred="true"} ! release of sequestered calcium ion into cytosol
 
 [Term]
 id: GO:1903515 ! calcium ion transport from cytosol to endoplasmic reticulum
 is_a: GO:0060401 {is_inferred="true"} ! cytosolic calcium ion transport
+is_a: GO:0070588 {is_inferred="true"} ! calcium ion transmembrane transport
 
 [Term]
 id: GO:1903516 ! regulation of single strand break repair
@@ -91010,6 +91038,11 @@
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
+id: GO:1990570 ! GDP-mannose transmembrane transport
+is_a: GO:0015784 {is_inferred="true"} ! GDP-mannose transport
+is_a: GO:0090480 {is_inferred="true"} ! purine nucleotide-sugar transmembrane transport
+
+[Term]
 id: GO:1990573 ! potassium ion import across plasma membrane
 is_a: GO:0071805 {is_inferred="true"} ! potassium ion transmembrane transport
 is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
@@ -91040,7 +91073,6 @@
 [Term]
 id: GO:1990591 ! asparagine transmembrane import into vacuole
 is_a: GO:0032975 {is_inferred="true"} ! amino acid transmembrane import into vacuole
-is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
 is_a: GO:0090469 {is_inferred="true"} ! asparagine import
 is_a: GO:1903713 {is_inferred="true"} ! asparagine transmembrane transport
 
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41276)
+++ go_inferences.obo	(working copy)
@@ -197,10 +197,6 @@
 is_a: GO:0006605 {is_inferred="true"} ! protein targeting
 
 [Term]
-id: GO:0000045 ! autophagosome assembly
-is_a: GO:1905037 {is_inferred="true"} ! autophagosome organization
-
-[Term]
 id: GO:0000049 ! tRNA binding
 is_a: GO:0003723 {is_inferred="true"} ! RNA binding
 
@@ -367,7 +363,6 @@
 [Term]
 id: GO:0000147 ! actin cortical patch assembly
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
-is_a: GO:0044396 {is_inferred="true"} ! actin cortical patch organization
 
 [Term]
 id: GO:0000148 ! 1,3-beta-D-glucan synthase complex
@@ -1066,7 +1061,6 @@
 
 [Term]
 id: GO:0000921 ! septin ring assembly
-is_a: GO:0031106 {is_inferred="true"} ! septin ring organization
 is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
 
 [Term]
@@ -1432,9 +1426,7 @@
 
 [Term]
 id: GO:0001675 ! acrosome assembly
-is_a: GO:0033363 {is_inferred="true"} ! secretory granule organization
 is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
-is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
 [Term]
 id: GO:0001676 ! long-chain fatty acid metabolic process
@@ -1613,11 +1605,6 @@
 is_a: GO:0051204 {is_inferred="true"} ! protein insertion into mitochondrial membrane
 
 [Term]
-id: GO:0001845 ! phagolysosome assembly
-is_a: GO:0007040 {is_inferred="true"} ! lysosome organization
-is_a: GO:0016050 {is_inferred="true"} ! vesicle organization
-
-[Term]
 id: GO:0001868 ! regulation of complement activation, lectin pathway
 is_a: GO:0030449 {is_inferred="true"} ! regulation of complement activation
 is_a: GO:0045088 {is_inferred="true"} ! regulation of innate immune response
@@ -7860,7 +7847,6 @@
 
 [Term]
 id: GO:0007019 ! microtubule depolymerization
-is_a: GO:0097435 {is_inferred="true"} ! supramolecular fiber organization
 is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
 [Term]
@@ -7868,13 +7854,10 @@
 is_a: GO:0031111 {is_inferred="true"} ! negative regulation of microtubule polymerization or depolymerization
 is_a: GO:0031114 {is_inferred="true"} ! regulation of microtubule depolymerization
 is_a: GO:1901880 {is_inferred="true"} ! negative regulation of protein depolymerization
-is_a: GO:1902904 {is_inferred="true"} ! negative regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0007027 ! negative regulation of axonemal microtubule depolymerization
 is_a: GO:0007026 {is_inferred="true"} ! negative regulation of microtubule depolymerization
-is_a: GO:0031345 {is_inferred="true"} ! negative regulation of cell projection organization
-is_a: GO:0120035 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:0007028 ! cytoplasm organization
@@ -8199,7 +8182,6 @@
 
 [Term]
 id: GO:0007287 ! Nebenkern assembly
-is_a: GO:0007005 {is_inferred="true"} ! mitochondrion organization
 is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
 
 [Term]
@@ -8340,7 +8322,6 @@
 [Term]
 id: GO:0007416 ! synapse assembly
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
-is_a: GO:0050808 {is_inferred="true"} ! synapse organization
 
 [Term]
 id: GO:0007444 ! imaginal disc development
@@ -13192,6 +13173,7 @@
 [Term]
 id: GO:0010937 ! regulation of cytoplasmic microtubule depolymerization
 is_a: GO:0031114 {is_inferred="true"} ! regulation of microtubule depolymerization
+is_a: GO:1902903 {is_inferred="true"} ! regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0010938 ! cytoplasmic microtubule depolymerization
@@ -20131,7 +20113,6 @@
 [Term]
 id: GO:0030239 ! myofibril assembly
 is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
-is_a: GO:0097435 {is_inferred="true"} ! supramolecular fiber organization
 
 [Term]
 id: GO:0030243 ! cellulose metabolic process
@@ -20344,7 +20325,6 @@
 [Term]
 id: GO:0030474 ! spindle pole body duplication
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
-is_a: GO:0051300 {is_inferred="true"} ! spindle pole body organization
 
 [Term]
 id: GO:0030476 ! ascospore wall assembly
@@ -21250,7 +21230,6 @@
 [Term]
 id: GO:0031025 ! equatorial microtubule organizing center disassembly
 is_a: GO:0022411 {is_inferred="true"} ! cellular component disassembly
-is_a: GO:0031023 {is_inferred="true"} ! microtubule organizing center organization
 is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
 [Term]
@@ -21354,7 +21333,6 @@
 
 [Term]
 id: GO:0031107 ! septin ring disassembly
-is_a: GO:0031106 {is_inferred="true"} ! septin ring organization
 is_a: GO:1903008 {is_inferred="true"} ! organelle disassembly
 
 [Term]
@@ -21379,13 +21357,11 @@
 id: GO:0031113 ! regulation of microtubule polymerization
 is_a: GO:0031110 {is_inferred="true"} ! regulation of microtubule polymerization or depolymerization
 is_a: GO:0032271 {is_inferred="true"} ! regulation of protein polymerization
-is_a: GO:1902903 {is_inferred="true"} ! regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0031114 ! regulation of microtubule depolymerization
 is_a: GO:0031110 {is_inferred="true"} ! regulation of microtubule polymerization or depolymerization
 is_a: GO:1901879 {is_inferred="true"} ! regulation of protein depolymerization
-is_a: GO:1902903 {is_inferred="true"} ! regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0031115 ! negative regulation of microtubule polymerization
@@ -21392,7 +21368,6 @@
 is_a: GO:0031111 {is_inferred="true"} ! negative regulation of microtubule polymerization or depolymerization
 is_a: GO:0031113 {is_inferred="true"} ! regulation of microtubule polymerization
 is_a: GO:0032272 {is_inferred="true"} ! negative regulation of protein polymerization
-is_a: GO:1902904 {is_inferred="true"} ! negative regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0031116 ! positive regulation of microtubule polymerization
@@ -21399,7 +21374,6 @@
 is_a: GO:0031112 {is_inferred="true"} ! positive regulation of microtubule polymerization or depolymerization
 is_a: GO:0031113 {is_inferred="true"} ! regulation of microtubule polymerization
 is_a: GO:0032273 {is_inferred="true"} ! positive regulation of protein polymerization
-is_a: GO:1902905 {is_inferred="true"} ! positive regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0031117 ! positive regulation of microtubule depolymerization
@@ -21406,7 +21380,6 @@
 is_a: GO:0031112 {is_inferred="true"} ! positive regulation of microtubule polymerization or depolymerization
 is_a: GO:0031114 {is_inferred="true"} ! regulation of microtubule depolymerization
 is_a: GO:1901881 {is_inferred="true"} ! positive regulation of protein depolymerization
-is_a: GO:1902905 {is_inferred="true"} ! positive regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0031122 ! cytoplasmic microtubule organization
@@ -21604,6 +21577,7 @@
 [Term]
 id: GO:0031272 ! regulation of pseudopodium assembly
 is_a: GO:0120032 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection assembly
+is_a: GO:0120035 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:0031273 ! negative regulation of pseudopodium assembly
@@ -25192,6 +25166,7 @@
 is_a: GO:0007026 {is_inferred="true"} ! negative regulation of microtubule depolymerization
 is_a: GO:0010948 {is_inferred="true"} ! negative regulation of cell cycle process
 is_a: GO:0090224 {is_inferred="true"} ! regulation of spindle organization
+is_a: GO:1902904 {is_inferred="true"} ! negative regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0032934 ! sterol binding
@@ -28580,10 +28555,6 @@
 is_a: GO:0022414 {is_inferred="true"} ! reproductive process
 
 [Term]
-id: GO:0035045 ! sperm plasma membrane disassembly
-is_a: GO:0007009 {is_inferred="true"} ! plasma membrane organization
-
-[Term]
 id: GO:0035046 ! pronuclear migration
 is_a: GO:0022414 {is_inferred="true"} ! reproductive process
 
@@ -30282,10 +30253,6 @@
 is_a: GO:0071418 {is_inferred="true"} ! cellular response to amine stimulus
 
 [Term]
-id: GO:0036258 ! multivesicular body assembly
-is_a: GO:0036257 {is_inferred="true"} ! multivesicular body organization
-
-[Term]
 id: GO:0036266 ! Cdc48p-Npl4p-Vms1p AAA ATPase complex
 is_a: GO:0098799 {is_inferred="true"} ! outer mitochondrial membrane protein complex
 
@@ -33033,7 +33000,6 @@
 [Term]
 id: GO:0043149 ! stress fiber assembly
 is_a: GO:0030038 {is_inferred="true"} ! contractile actin filament bundle assembly
-is_a: GO:0031032 {is_inferred="true"} ! actomyosin structure organization
 
 [Term]
 id: GO:0043150 ! DNA synthesis involved in double-strand break repair via homologous recombination
@@ -35015,10 +34981,6 @@
 is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
 
 [Term]
-id: GO:0044854 ! plasma membrane raft assembly
-is_a: GO:0044857 {is_inferred="true"} ! plasma membrane raft organization
-
-[Term]
 id: GO:0044859 ! protein insertion into plasma membrane raft
 is_a: GO:0044860 {is_inferred="true"} ! protein localization to plasma membrane raft
 is_a: GO:0071210 {is_inferred="true"} ! protein insertion into membrane raft
@@ -40547,11 +40509,6 @@
 is_a: GO:0050792 {is_inferred="true"} ! regulation of viral process
 
 [Term]
-id: GO:0046785 ! microtubule polymerization
-is_a: GO:0097435 {is_inferred="true"} ! supramolecular fiber organization
-is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
-
-[Term]
 id: GO:0046807 ! viral scaffold assembly and maintenance
 is_a: GO:0016032 {is_inferred="true"} ! viral process
 
@@ -43553,6 +43510,7 @@
 
 [Term]
 id: GO:0051230 ! spindle disassembly
+is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 is_a: GO:1903008 {is_inferred="true"} ! organelle disassembly
 
 [Term]
@@ -45180,13 +45138,13 @@
 [Term]
 id: GO:0051963 ! regulation of synapse assembly
 is_a: GO:0044087 {is_inferred="true"} ! regulation of cellular component biogenesis
-is_a: GO:0050807 {is_inferred="true"} ! regulation of synapse organization
+is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 is_a: GO:0051960 {is_inferred="true"} ! regulation of nervous system development
 
 [Term]
 id: GO:0051964 ! negative regulation of synapse assembly
+is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:0051963 {is_inferred="true"} ! regulation of synapse assembly
-is_a: GO:1905809 {is_inferred="true"} ! negative regulation of synapse organization
 
 [Term]
 id: GO:0051965 ! positive regulation of synapse assembly
@@ -46312,7 +46270,6 @@
 
 [Term]
 id: GO:0060271 ! cilium assembly
-is_a: GO:0044782 {is_inferred="true"} ! cilium organization
 is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
 is_a: GO:0120031 {is_inferred="true"} ! plasma membrane bounded cell projection assembly
 
@@ -46368,7 +46325,6 @@
 is_a: GO:0051153 {is_inferred="true"} ! regulation of striated muscle cell differentiation
 is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
 is_a: GO:1902115 {is_inferred="true"} ! regulation of organelle assembly
-is_a: GO:1902903 {is_inferred="true"} ! regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0060298 ! positive regulation of sarcomere organization
@@ -46377,7 +46333,6 @@
 is_a: GO:0051495 {is_inferred="true"} ! positive regulation of cytoskeleton organization
 is_a: GO:0060297 {is_inferred="true"} ! regulation of sarcomere organization
 is_a: GO:1902117 {is_inferred="true"} ! positive regulation of organelle assembly
-is_a: GO:1902905 {is_inferred="true"} ! positive regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0060299 ! negative regulation of sarcomere organization
@@ -46386,7 +46341,6 @@
 is_a: GO:0051494 {is_inferred="true"} ! negative regulation of cytoskeleton organization
 is_a: GO:0060297 {is_inferred="true"} ! regulation of sarcomere organization
 is_a: GO:1902116 {is_inferred="true"} ! negative regulation of organelle assembly
-is_a: GO:1902904 {is_inferred="true"} ! negative regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0060300 ! regulation of cytokine activity
@@ -48964,7 +48918,6 @@
 
 [Term]
 id: GO:0061523 ! cilium disassembly
-is_a: GO:0044782 {is_inferred="true"} ! cilium organization
 is_a: GO:1903008 {is_inferred="true"} ! organelle disassembly
 
 [Term]
@@ -49156,10 +49109,6 @@
 is_a: GO:0005980 {is_inferred="true"} ! glycogen catabolic process
 
 [Term]
-id: GO:0061726 ! mitochondrion disassembly
-is_a: GO:0007005 {is_inferred="true"} ! mitochondrion organization
-
-[Term]
 id: GO:0061727 ! methylglyoxal catabolic process to lactate
 is_a: GO:0006089 {is_inferred="true"} ! lactate metabolic process
 
@@ -50708,10 +50657,6 @@
 is_a: GO:0098802 {is_inferred="true"} ! plasma membrane receptor complex
 
 [Term]
-id: GO:0070726 ! cell wall assembly
-is_a: GO:0071555 {is_inferred="true"} ! cell wall organization
-
-[Term]
 id: GO:0070728 ! leucine binding
 is_a: GO:0016597 {is_inferred="true"} ! amino acid binding
 is_a: GO:0043169 {is_inferred="true"} ! cation binding
@@ -51176,10 +51121,6 @@
 is_a: GO:0070869 {is_inferred="true"} ! heterochromatin assembly involved in chromatin silencing
 
 [Term]
-id: GO:0070925 ! organelle assembly
-is_a: GO:0006996 {is_inferred="true"} ! organelle organization
-
-[Term]
 id: GO:0070926 ! regulation of ATP:ADP antiporter activity
 is_a: GO:0032239 {is_inferred="true"} ! regulation of nucleobase-containing compound transport
 is_a: GO:0032412 {is_inferred="true"} ! regulation of ion transmembrane transporter activity
@@ -53441,10 +53382,6 @@
 is_a: GO:0050660 {is_inferred="true"} ! flavin adenine dinucleotide binding
 
 [Term]
-id: GO:0071971 ! extracellular exosome assembly
-is_a: GO:0016050 {is_inferred="true"} ! vesicle organization
-
-[Term]
 id: GO:0071986 ! Ragulator complex
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 
@@ -56594,6 +56531,7 @@
 
 [Term]
 id: GO:0090166 ! Golgi disassembly
+is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 is_a: GO:1903008 {is_inferred="true"} ! organelle disassembly
 
 [Term]
@@ -57950,13 +57888,11 @@
 
 [Term]
 id: GO:0097104 ! postsynaptic membrane assembly
-is_a: GO:0001941 {is_inferred="true"} ! postsynaptic membrane organization
 is_a: GO:0071709 {is_inferred="true"} ! membrane assembly
 
 [Term]
 id: GO:0097105 ! presynaptic membrane assembly
 is_a: GO:0071709 {is_inferred="true"} ! membrane assembly
-is_a: GO:0097090 {is_inferred="true"} ! presynaptic membrane organization
 
 [Term]
 id: GO:0097106 ! postsynaptic density organization
@@ -57964,7 +57900,6 @@
 
 [Term]
 id: GO:0097107 ! postsynaptic density assembly
-is_a: GO:0097106 {is_inferred="true"} ! postsynaptic density organization
 is_a: GO:0098698 {is_inferred="true"} ! postsynaptic specialization assembly
 
 [Term]
@@ -58990,7 +58925,6 @@
 [Term]
 id: GO:0098698 ! postsynaptic specialization assembly
 is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
-is_a: GO:0099084 {is_inferred="true"} ! postsynaptic specialization organization
 
 [Term]
 id: GO:0098700 ! neurotransmitter loading into synaptic vesicle
@@ -59208,12 +59142,10 @@
 [Term]
 id: GO:0098785 ! biofilm matrix assembly
 is_a: GO:0085029 {is_inferred="true"} ! extracellular matrix assembly
-is_a: GO:0098784 {is_inferred="true"} ! biofilm matrix organization
 
 [Term]
 id: GO:0098786 ! biofilm matrix disassembly
 is_a: GO:0022617 {is_inferred="true"} ! extracellular matrix disassembly
-is_a: GO:0098784 {is_inferred="true"} ! biofilm matrix organization
 
 [Term]
 id: GO:0098791 ! Golgi subcompartment
@@ -61268,12 +61200,10 @@
 [Term]
 id: GO:0120031 ! plasma membrane bounded cell projection assembly
 is_a: GO:0030031 {is_inferred="true"} ! cell projection assembly
-is_a: GO:0120036 {is_inferred="true"} ! plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly
 is_a: GO:0060491 {is_inferred="true"} ! regulation of cell projection assembly
-is_a: GO:0120035 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly
@@ -61472,6 +61402,7 @@
 [Term]
 id: GO:1900027 ! regulation of ruffle assembly
 is_a: GO:0120032 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection assembly
+is_a: GO:0120035 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:1900028 ! negative regulation of ruffle assembly
@@ -72133,18 +72064,18 @@
 
 [Term]
 id: GO:1902115 ! regulation of organelle assembly
-is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
 is_a: GO:0044087 {is_inferred="true"} ! regulation of cellular component biogenesis
+is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 
 [Term]
 id: GO:1902116 ! negative regulation of organelle assembly
-is_a: GO:0010639 {is_inferred="true"} ! negative regulation of organelle organization
+is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:1902115 {is_inferred="true"} ! regulation of organelle assembly
 
 [Term]
 id: GO:1902117 ! positive regulation of organelle assembly
-is_a: GO:0010638 {is_inferred="true"} ! positive regulation of organelle organization
 is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
+is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 is_a: GO:1902115 {is_inferred="true"} ! regulation of organelle assembly
 
 [Term]
@@ -72608,11 +72539,13 @@
 
 [Term]
 id: GO:1902208 ! regulation of bacterial-type flagellum assembly
+is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
 is_a: GO:0060491 {is_inferred="true"} ! regulation of cell projection assembly
 is_a: GO:1902115 {is_inferred="true"} ! regulation of organelle assembly
 
 [Term]
 id: GO:1902209 ! negative regulation of bacterial-type flagellum assembly
+is_a: GO:0010639 {is_inferred="true"} ! negative regulation of organelle organization
 is_a: GO:0031345 {is_inferred="true"} ! negative regulation of cell projection organization
 is_a: GO:1902116 {is_inferred="true"} ! negative regulation of organelle assembly
 is_a: GO:1902208 {is_inferred="true"} ! regulation of bacterial-type flagellum assembly
@@ -72619,6 +72552,7 @@
 
 [Term]
 id: GO:1902210 ! positive regulation of bacterial-type flagellum assembly
+is_a: GO:0010638 {is_inferred="true"} ! positive regulation of organelle organization
 is_a: GO:0031346 {is_inferred="true"} ! positive regulation of cell projection organization
 is_a: GO:1902117 {is_inferred="true"} ! positive regulation of organelle assembly
 is_a: GO:1902208 {is_inferred="true"} ! regulation of bacterial-type flagellum assembly
@@ -74520,7 +74454,6 @@
 [Term]
 id: GO:1902621 ! actomyosin contractile ring disassembly
 is_a: GO:0022411 {is_inferred="true"} ! cellular component disassembly
-is_a: GO:0044837 {is_inferred="true"} ! actomyosin contractile ring organization
 
 [Term]
 id: GO:1902622 ! regulation of neutrophil migration
@@ -75795,7 +75728,6 @@
 
 [Term]
 id: GO:1902896 ! terminal web assembly
-is_a: GO:0030866 {is_inferred="true"} ! cortical actin cytoskeleton organization
 is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
 
 [Term]
@@ -75815,7 +75747,6 @@
 
 [Term]
 id: GO:1902900 ! gut granule assembly
-is_a: GO:0016050 {is_inferred="true"} ! vesicle organization
 is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
 
 [Term]
@@ -75824,7 +75755,6 @@
 
 [Term]
 id: GO:1902902 ! negative regulation of autophagosome assembly
-is_a: GO:0016242 {is_inferred="true"} ! negative regulation of macroautophagy
 is_a: GO:1902116 {is_inferred="true"} ! negative regulation of organelle assembly
 is_a: GO:2000785 {is_inferred="true"} ! regulation of autophagosome assembly
 
@@ -76339,7 +76269,6 @@
 [Term]
 id: GO:1903008 ! organelle disassembly
 is_a: GO:0022411 {is_inferred="true"} ! cellular component disassembly
-is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
 [Term]
 id: GO:1903009 ! proteasome complex disassembly
@@ -76926,12 +76855,12 @@
 [Term]
 id: GO:1903146 ! regulation of mitophagy
 is_a: GO:0010506 {is_inferred="true"} ! regulation of autophagy
-is_a: GO:0010821 {is_inferred="true"} ! regulation of mitochondrion organization
+is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 
 [Term]
 id: GO:1903147 ! negative regulation of mitophagy
 is_a: GO:0010507 {is_inferred="true"} ! negative regulation of autophagy
-is_a: GO:0010823 {is_inferred="true"} ! negative regulation of mitochondrion organization
+is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:1903146 {is_inferred="true"} ! regulation of mitophagy
 
 [Term]
@@ -77276,7 +77205,6 @@
 
 [Term]
 id: GO:1903232 ! melanosome assembly
-is_a: GO:0032438 {is_inferred="true"} ! melanosome organization
 is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
 
 [Term]
@@ -78869,10 +78797,6 @@
 is_a: GO:1903832 {is_inferred="true"} ! regulation of cellular response to amino acid starvation
 
 [Term]
-id: GO:1903575 ! cornified envelope assembly
-is_a: GO:0007009 {is_inferred="true"} ! plasma membrane organization
-
-[Term]
 id: GO:1903576 ! response to L-arginine
 is_a: GO:0043200 {is_inferred="true"} ! response to amino acid
 
@@ -79009,7 +78933,7 @@
 [Term]
 id: GO:1903599 ! positive regulation of mitophagy
 is_a: GO:0010508 {is_inferred="true"} ! positive regulation of autophagy
-is_a: GO:0010822 {is_inferred="true"} ! positive regulation of mitochondrion organization
+is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 is_a: GO:1903146 {is_inferred="true"} ! regulation of mitophagy
 
 [Term]
@@ -80254,13 +80178,10 @@
 [Term]
 id: GO:1903863 ! P granule assembly
 is_a: GO:0022618 {is_inferred="true"} ! ribonucleoprotein complex assembly
-is_a: GO:0030719 {is_inferred="true"} ! P granule organization
 is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
 
 [Term]
 id: GO:1903864 ! P granule disassembly
-is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
-is_a: GO:0030719 {is_inferred="true"} ! P granule organization
 is_a: GO:0032988 {is_inferred="true"} ! ribonucleoprotein complex disassembly
 is_a: GO:1903008 {is_inferred="true"} ! organelle disassembly
 
@@ -81778,7 +81699,6 @@
 [Term]
 id: GO:1904185 ! equatorial microtubule organizing center assembly
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
-is_a: GO:0031023 {is_inferred="true"} ! microtubule organizing center organization
 
 [Term]
 id: GO:1904186 ! post-anaphase microtubule array organization
@@ -82121,7 +82041,6 @@
 [Term]
 id: GO:1904258 ! nuclear dicing body assembly
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
-is_a: GO:0030575 {is_inferred="true"} ! nuclear body organization
 
 [Term]
 id: GO:1904259 ! regulation of basement membrane assembly involved in embryonic body morphogenesis
@@ -84882,7 +84801,6 @@
 
 [Term]
 id: GO:1904821 ! chloroplast disassembly
-is_a: GO:0009658 {is_inferred="true"} ! chloroplast organization
 is_a: GO:1903008 {is_inferred="true"} ! organelle disassembly
 
 [Term]
@@ -86134,7 +86052,6 @@
 [Term]
 id: GO:1905071 ! occluding junction disassembly
 is_a: GO:0022411 {is_inferred="true"} ! cellular component disassembly
-is_a: GO:0045216 {is_inferred="true"} ! cell-cell junction organization
 
 [Term]
 id: GO:1905072 ! cardiac jelly development
@@ -87249,7 +87166,6 @@
 is_a: GO:0032956 {is_inferred="true"} ! regulation of actin cytoskeleton organization
 is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
 is_a: GO:1902115 {is_inferred="true"} ! regulation of organelle assembly
-is_a: GO:1902903 {is_inferred="true"} ! regulation of supramolecular fiber organization
 is_a: GO:2000725 {is_inferred="true"} ! regulation of cardiac muscle cell differentiation
 
 [Term]
@@ -87257,7 +87173,6 @@
 is_a: GO:0010721 {is_inferred="true"} ! negative regulation of cell development
 is_a: GO:0051494 {is_inferred="true"} ! negative regulation of cytoskeleton organization
 is_a: GO:1902116 {is_inferred="true"} ! negative regulation of organelle assembly
-is_a: GO:1902904 {is_inferred="true"} ! negative regulation of supramolecular fiber organization
 is_a: GO:1905304 {is_inferred="true"} ! regulation of cardiac myofibril assembly
 is_a: GO:2000726 {is_inferred="true"} ! negative regulation of cardiac muscle cell differentiation
 
@@ -87266,7 +87181,6 @@
 is_a: GO:0010720 {is_inferred="true"} ! positive regulation of cell development
 is_a: GO:0051495 {is_inferred="true"} ! positive regulation of cytoskeleton organization
 is_a: GO:1902117 {is_inferred="true"} ! positive regulation of organelle assembly
-is_a: GO:1902905 {is_inferred="true"} ! positive regulation of supramolecular fiber organization
 is_a: GO:1905304 {is_inferred="true"} ! regulation of cardiac myofibril assembly
 is_a: GO:2000727 {is_inferred="true"} ! positive regulation of cardiac muscle cell differentiation
 
@@ -88273,6 +88187,7 @@
 
 [Term]
 id: GO:1905518 ! regulation of presynaptic active zone assembly
+is_a: GO:0050807 {is_inferred="true"} ! regulation of synapse organization
 is_a: GO:1905606 {is_inferred="true"} ! regulation of presynapse assembly
 
 [Term]
@@ -88279,6 +88194,7 @@
 id: GO:1905519 ! negative regulation of presynaptic active zone assembly
 is_a: GO:1905518 {is_inferred="true"} ! regulation of presynaptic active zone assembly
 is_a: GO:1905607 {is_inferred="true"} ! negative regulation of presynapse assembly
+is_a: GO:1905809 {is_inferred="true"} ! negative regulation of synapse organization
 
 [Term]
 id: GO:1905520 ! positive regulation of presynaptic active zone assembly
@@ -88438,7 +88354,6 @@
 
 [Term]
 id: GO:1905556 ! ciliary vesicle assembly
-is_a: GO:0016050 {is_inferred="true"} ! vesicle organization
 is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
 
 [Term]
@@ -89047,7 +88962,6 @@
 
 [Term]
 id: GO:1905683 ! peroxisome disassembly
-is_a: GO:0007031 {is_inferred="true"} ! peroxisome organization
 is_a: GO:1903008 {is_inferred="true"} ! organelle disassembly
 
 [Term]
@@ -89083,17 +88997,14 @@
 
 [Term]
 id: GO:1905690 ! nucleus disassembly
-is_a: GO:0006997 {is_inferred="true"} ! nucleus organization
 is_a: GO:1903008 {is_inferred="true"} ! organelle disassembly
 
 [Term]
 id: GO:1905691 ! lipid particle disassembly
-is_a: GO:0034389 {is_inferred="true"} ! lipid particle organization
 is_a: GO:1903008 {is_inferred="true"} ! organelle disassembly
 
 [Term]
 id: GO:1905692 ! endoplasmic reticulum disassembly
-is_a: GO:0007029 {is_inferred="true"} ! endoplasmic reticulum organization
 is_a: GO:1903008 {is_inferred="true"} ! organelle disassembly
 
 [Term]
@@ -89888,7 +89799,6 @@
 [Term]
 id: GO:1905861 ! intranuclear rod assembly
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
-is_a: GO:0097435 {is_inferred="true"} ! supramolecular fiber organization
 
 [Term]
 id: GO:1905862 ! ferroxidase complex
@@ -89964,12 +89874,10 @@
 [Term]
 id: GO:1905877 ! invadopodium assembly
 is_a: GO:0120031 {is_inferred="true"} ! plasma membrane bounded cell projection assembly
-is_a: GO:1905863 {is_inferred="true"} ! invadopodium organization
 
 [Term]
 id: GO:1905878 ! invadopodium disassembly
 is_a: GO:0022411 {is_inferred="true"} ! cellular component disassembly
-is_a: GO:1905863 {is_inferred="true"} ! invadopodium organization
 
 [Term]
 id: GO:1905879 ! regulation of oogenesis
@@ -90223,16 +90131,16 @@
 
 [Term]
 id: GO:1905927 ! regulation of invadopodium disassembly
-is_a: GO:0120035 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection organization
+is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 
 [Term]
 id: GO:1905928 ! negative regulation of invadopodium disassembly
-is_a: GO:0031345 {is_inferred="true"} ! negative regulation of cell projection organization
+is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:1905927 {is_inferred="true"} ! regulation of invadopodium disassembly
 
 [Term]
 id: GO:1905929 ! positive regulation of invadopodium disassembly
-is_a: GO:0031346 {is_inferred="true"} ! positive regulation of cell projection organization
+is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 is_a: GO:1905927 {is_inferred="true"} ! regulation of invadopodium disassembly
 
 [Term]
@@ -95288,14 +95196,10 @@
 
 [Term]
 id: GO:2000785 ! regulation of autophagosome assembly
-is_a: GO:0016241 {is_inferred="true"} ! regulation of macroautophagy
-is_a: GO:0044088 {is_inferred="true"} ! regulation of vacuole organization
 is_a: GO:1902115 {is_inferred="true"} ! regulation of organelle assembly
 
 [Term]
 id: GO:2000786 ! positive regulation of autophagosome assembly
-is_a: GO:0016239 {is_inferred="true"} ! positive regulation of macroautophagy
-is_a: GO:0044090 {is_inferred="true"} ! positive regulation of vacuole organization
 is_a: GO:1902117 {is_inferred="true"} ! positive regulation of organelle assembly
 is_a: GO:2000785 {is_inferred="true"} ! regulation of autophagosome assembly
 
------------------------------------------------------------------------
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changes in entailments

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changes in entailments

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changes in entailments

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changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41254)
+++ go_inferences.obo	(working copy)
@@ -50645,6 +50645,10 @@
 is_a: GO:0070656 {is_inferred="true"} ! mechanoreceptor differentiation involved in mechanosensory epithelium regeneration
 
 [Term]
+id: GO:0070664 ! negative regulation of leukocyte proliferation
+is_a: GO:0070663 {is_inferred="true"} ! regulation of leukocyte proliferation
+
+[Term]
 id: GO:0070666 ! regulation of mast cell proliferation
 is_a: GO:0070663 {is_inferred="true"} ! regulation of leukocyte proliferation
 
@@ -61287,6 +61291,20 @@
 is_a: GO:0030030 {is_inferred="true"} ! cell projection organization
 
 [Term]
+id: GO:0120040 ! regulation of macrophage proliferation
+is_a: GO:0070663 {is_inferred="true"} ! regulation of leukocyte proliferation
+
+[Term]
+id: GO:0120041 ! positive regulation of macrophage proliferation
+is_a: GO:0070665 {is_inferred="true"} ! positive regulation of leukocyte proliferation
+is_a: GO:0120040 {is_inferred="true"} ! regulation of macrophage proliferation
+
+[Term]
+id: GO:0120042 ! negative regulation of macrophage proliferation
+is_a: GO:0070664 {is_inferred="true"} ! negative regulation of leukocyte proliferation
+is_a: GO:0120040 {is_inferred="true"} ! regulation of macrophage proliferation
+
+[Term]
 id: GO:0140009 ! L-aspartate import across plasma membrane
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 is_a: GO:0089712 {is_inferred="true"} ! L-aspartate transmembrane transport
------------------------------------------------------------------------
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changes in entailments

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changes in entailments

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changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41250)
+++ go_inferences.obo	(working copy)
@@ -10234,10 +10234,6 @@
 is_a: GO:0098543 {is_inferred="true"} ! detection of other organism
 
 [Term]
-id: GO:0009615 ! response to virus
-is_a: GO:0016032 {is_inferred="true"} ! viral process
-
-[Term]
 id: GO:0009654 ! photosystem II oxygen evolving complex
 is_a: GO:0044436 {is_inferred="true"} ! thylakoid part
 is_a: GO:1990204 {is_inferred="true"} ! oxidoreductase complex
@@ -11743,6 +11739,10 @@
 is_a: GO:1901137 {is_inferred="true"} ! carbohydrate derivative biosynthetic process
 
 [Term]
+id: GO:0010497 ! plasmodesmata-mediated intercellular transport
+is_a: GO:0010496 {is_inferred="true"} ! intercellular transport
+
+[Term]
 id: GO:0010498 ! proteasomal protein catabolic process
 is_a: GO:0030163 {is_inferred="true"} ! protein catabolic process
 
@@ -17415,24 +17415,10 @@
 is_a: GO:0019015 {is_inferred="true"} ! viral genome
 
 [Term]
-id: GO:0019068 ! virion assembly
-is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
-is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
-
-[Term]
 id: GO:0019069 ! viral capsid assembly
-is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
-is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
+is_a: GO:0016032 {is_inferred="true"} ! viral process
 
 [Term]
-id: GO:0019073 ! viral DNA genome packaging
-is_a: GO:1902590 {is_inferred="true"} ! multi-organism organelle organization
-
-[Term]
-id: GO:0019080 ! viral gene expression
-is_a: GO:0044033 {is_inferred="true"} ! multi-organism metabolic process
-
-[Term]
 id: GO:0019090 ! mitochondrial rRNA export from mitochondrion
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
@@ -25096,10 +25082,8 @@
 
 [Term]
 id: GO:0032897 ! negative regulation of viral transcription
-is_a: GO:0010629 {is_inferred="true"} ! negative regulation of gene expression
 is_a: GO:0046782 {is_inferred="true"} ! regulation of viral transcription
-is_a: GO:1902679 {is_inferred="true"} ! negative regulation of RNA biosynthetic process
-is_a: GO:1903901 {is_inferred="true"} ! negative regulation of viral life cycle
+is_a: GO:0048525 {is_inferred="true"} ! negative regulation of viral process
 
 [Term]
 id: GO:0032899 ! regulation of neurotrophin production
@@ -29788,10 +29772,6 @@
 is_a: GO:0031221 {is_inferred="true"} ! arabinan metabolic process
 
 [Term]
-id: GO:0035915 ! pore formation in membrane of other organism
-is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
-
-[Term]
 id: GO:0035923 ! flurbiprofen binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 
@@ -30711,15 +30691,6 @@
 is_a: GO:0039535 {is_inferred="true"} ! regulation of RIG-I signaling pathway
 
 [Term]
-id: GO:0039537 ! suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway
-is_a: GO:0044831 {is_inferred="true"} ! modulation by virus of host cytokine production
-
-[Term]
-id: GO:0039567 ! suppression by virus of host STAT1 activity by negative regulation of STAT protein import into nucleus
-is_a: GO:0044833 {is_inferred="true"} ! modulation by virus of host protein transport
-is_a: GO:1990215 {is_inferred="true"} ! negative regulation by symbiont of host intracellular transport
-
-[Term]
 id: GO:0039570 ! suppression by virus of host STAT2 activity by negative regulation of STAT protein import into nucleus
 is_a: GO:0044833 {is_inferred="true"} ! modulation by virus of host protein transport
 is_a: GO:1990215 {is_inferred="true"} ! negative regulation by symbiont of host intracellular transport
@@ -30729,10 +30700,6 @@
 is_a: GO:0039588 {is_inferred="true"} ! suppression by virus of host antigen processing and presentation
 
 [Term]
-id: GO:0039599 ! cleavage by virus of host mRNA
-is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
-
-[Term]
 id: GO:0039631 ! DNA translocase activity involved in viral DNA genome packaging
 is_a: GO:0015616 {is_inferred="true"} ! DNA translocase activity
 
@@ -30741,57 +30708,27 @@
 is_a: GO:0039630 {is_inferred="true"} ! RNA translocase activity
 
 [Term]
-id: GO:0039637 ! catabolism by virus of host DNA
-is_a: GO:0044035 {is_inferred="true"} ! multi-organism catabolic process
-is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
-
-[Term]
 id: GO:0039642 ! virion nucleoid
 is_a: GO:0009295 {is_inferred="true"} ! nucleoid
 is_a: GO:0044423 {is_inferred="true"} ! virion part
 
 [Term]
-id: GO:0039667 ! viral entry into host cell via pilus retraction
-is_a: GO:0016032 {is_inferred="true"} ! viral process
+id: GO:0039708 ! nuclear capsid assembly
+is_a: GO:0019069 {is_inferred="true"} ! viral capsid assembly
 
 [Term]
-id: GO:0039688 ! viral double stranded DNA replication via reverse transcription
-is_a: GO:0016070 {is_inferred="true"} ! RNA metabolic process
+id: GO:0039709 ! cytoplasmic capsid assembly
+is_a: GO:0019069 {is_inferred="true"} ! viral capsid assembly
 
 [Term]
-id: GO:0039689 ! negative stranded viral RNA replication
-is_a: GO:0044034 {is_inferred="true"} ! multi-organism biosynthetic process
+id: GO:0039710 ! cytoplasmic icosahedral capsid assembly
+is_a: GO:0039709 {is_inferred="true"} ! cytoplasmic capsid assembly
 
 [Term]
-id: GO:0039690 ! positive stranded viral RNA replication
-is_a: GO:0044034 {is_inferred="true"} ! multi-organism biosynthetic process
+id: GO:0039711 ! cytoplasmic helical capsid assembly
+is_a: GO:0039709 {is_inferred="true"} ! cytoplasmic capsid assembly
 
 [Term]
-id: GO:0039691 ! double stranded viral RNA replication
-is_a: GO:0044034 {is_inferred="true"} ! multi-organism biosynthetic process
-
-[Term]
-id: GO:0039692 ! single stranded viral RNA replication via double stranded DNA intermediate
-is_a: GO:0006259 {is_inferred="true"} ! DNA metabolic process
-
-[Term]
-id: GO:0039693 ! viral DNA genome replication
-is_a: GO:0044034 {is_inferred="true"} ! multi-organism biosynthetic process
-is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
-
-[Term]
-id: GO:0039694 ! viral RNA genome replication
-is_a: GO:0044033 {is_inferred="true"} ! multi-organism metabolic process
-is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
-
-[Term]
-id: GO:0039699 ! viral mRNA cap methylation
-is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
-is_a: GO:0044033 {is_inferred="true"} ! multi-organism metabolic process
-is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
-is_a: GO:1901698 {is_inferred="true"} ! response to nitrogen compound
-
-[Term]
 id: GO:0040001 ! establishment of mitotic spindle localization
 is_a: GO:0051293 {is_inferred="true"} ! establishment of spindle localization
 is_a: GO:1902850 {is_inferred="true"} ! microtubule cytoskeleton organization involved in mitosis
@@ -34411,7 +34348,7 @@
 
 [Term]
 id: GO:0043948 ! positive regulation by symbiont of host catalytic activity
-is_a: GO:0043947 {is_inferred="true"} ! positive regulation by host of symbiont catalytic activity
+is_a: GO:0043085 {is_inferred="true"} ! positive regulation of catalytic activity
 
 [Term]
 id: GO:0043949 ! regulation of cAMP-mediated signaling
@@ -35053,10 +34990,6 @@
 is_a: GO:0045070 {is_inferred="true"} ! positive regulation of viral genome replication
 
 [Term]
-id: GO:0044830 ! modulation by host of viral RNA genome replication
-is_a: GO:0051252 {is_inferred="true"} ! regulation of RNA metabolic process
-
-[Term]
 id: GO:0044831 ! modulation by virus of host cytokine production
 is_a: GO:0001817 {is_inferred="true"} ! regulation of cytokine production
 
@@ -35107,9 +35040,14 @@
 
 [Term]
 id: GO:0044866 ! modulation by host of viral exo-alpha-sialidase activity
+is_a: GO:0044867 {is_inferred="true"} ! modulation by host of viral catalytic activity
 is_a: GO:1903015 {is_inferred="true"} ! regulation of exo-alpha-sialidase activity
 
 [Term]
+id: GO:0044867 ! modulation by host of viral catalytic activity
+is_a: GO:0044868 {is_inferred="true"} ! modulation by host of viral molecular function
+
+[Term]
 id: GO:0044869 ! negative regulation by host of viral exo-alpha-sialidase activity
 is_a: GO:1903016 {is_inferred="true"} ! negative regulation of exo-alpha-sialidase activity
 
@@ -35304,8 +35242,6 @@
 [Term]
 id: GO:0045091 ! regulation of single stranded viral RNA replication via double stranded DNA intermediate
 is_a: GO:0045069 {is_inferred="true"} ! regulation of viral genome replication
-is_a: GO:0051052 {is_inferred="true"} ! regulation of DNA metabolic process
-is_a: GO:0051252 {is_inferred="true"} ! regulation of RNA metabolic process
 
 [Term]
 id: GO:0045092 ! interleukin-18 receptor complex
@@ -37556,15 +37492,11 @@
 id: GO:0045869 ! negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
 is_a: GO:0045071 {is_inferred="true"} ! negative regulation of viral genome replication
 is_a: GO:0045091 {is_inferred="true"} ! regulation of single stranded viral RNA replication via double stranded DNA intermediate
-is_a: GO:0051053 {is_inferred="true"} ! negative regulation of DNA metabolic process
-is_a: GO:0051253 {is_inferred="true"} ! negative regulation of RNA metabolic process
 
 [Term]
 id: GO:0045870 ! positive regulation of single stranded viral RNA replication via double stranded DNA intermediate
 is_a: GO:0045070 {is_inferred="true"} ! positive regulation of viral genome replication
 is_a: GO:0045091 {is_inferred="true"} ! regulation of single stranded viral RNA replication via double stranded DNA intermediate
-is_a: GO:0051054 {is_inferred="true"} ! positive regulation of DNA metabolic process
-is_a: GO:0051254 {is_inferred="true"} ! positive regulation of RNA metabolic process
 
 [Term]
 id: GO:0045873 ! negative regulation of sevenless signaling pathway
@@ -40583,23 +40515,36 @@
 
 [Term]
 id: GO:0046752 ! viral capsid precursor transport to host cell nucleus
-is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
+is_a: GO:0030581 {is_inferred="true"} ! symbiont intracellular protein transport in host
 is_a: GO:0075733 {is_inferred="true"} ! intracellular transport of virus
 
 [Term]
-id: GO:0046773 ! suppression by virus of host translation termination
-is_a: GO:0044034 {is_inferred="true"} ! multi-organism biosynthetic process
-is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
+id: GO:0046760 ! viral budding from Golgi membrane
+is_a: GO:0046755 {is_inferred="true"} ! viral budding
 
 [Term]
+id: GO:0046762 ! viral budding from ER membrane
+is_a: GO:0046755 {is_inferred="true"} ! viral budding
+
+[Term]
+id: GO:0046765 ! viral budding from nuclear membrane
+is_a: GO:0046755 {is_inferred="true"} ! viral budding
+
+[Term]
+id: GO:0046771 ! viral budding from inner nuclear membrane
+is_a: GO:0046765 {is_inferred="true"} ! viral budding from nuclear membrane
+
+[Term]
+id: GO:0046772 ! viral budding from outer nuclear membrane
+is_a: GO:0046765 {is_inferred="true"} ! viral budding from nuclear membrane
+
+[Term]
 id: GO:0046776 ! suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I
 is_a: GO:0002590 {is_inferred="true"} ! negative regulation of antigen processing and presentation of peptide antigen via MHC class I
 
 [Term]
 id: GO:0046782 ! regulation of viral transcription
-is_a: GO:0010468 {is_inferred="true"} ! regulation of gene expression
-is_a: GO:1903900 {is_inferred="true"} ! regulation of viral life cycle
-is_a: GO:2001141 {is_inferred="true"} ! regulation of RNA biosynthetic process
+is_a: GO:0050792 {is_inferred="true"} ! regulation of viral process
 
 [Term]
 id: GO:0046785 ! microtubule polymerization
@@ -40608,8 +40553,7 @@
 
 [Term]
 id: GO:0046807 ! viral scaffold assembly and maintenance
-is_a: GO:0006461 {is_inferred="true"} ! protein complex assembly
-is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
+is_a: GO:0016032 {is_inferred="true"} ! viral process
 
 [Term]
 id: GO:0046819 ! protein secretion by the type V secretion system
@@ -42288,10 +42232,8 @@
 
 [Term]
 id: GO:0050434 ! positive regulation of viral transcription
-is_a: GO:0010628 {is_inferred="true"} ! positive regulation of gene expression
 is_a: GO:0046782 {is_inferred="true"} ! regulation of viral transcription
-is_a: GO:1902680 {is_inferred="true"} ! positive regulation of RNA biosynthetic process
-is_a: GO:1903902 {is_inferred="true"} ! positive regulation of viral life cycle
+is_a: GO:0048524 {is_inferred="true"} ! positive regulation of viral process
 
 [Term]
 id: GO:0050435 ! beta-amyloid metabolic process
@@ -42439,7 +42381,7 @@
 is_a: GO:0002832 {is_inferred="true"} ! negative regulation of response to biotic stimulus
 is_a: GO:0031348 {is_inferred="true"} ! negative regulation of defense response
 is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
-is_a: GO:0048525 {is_inferred="true"} ! negative regulation of viral process
+is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:0050688 {is_inferred="true"} ! regulation of defense response to virus
 
 [Term]
@@ -42448,7 +42390,7 @@
 is_a: GO:0002831 {is_inferred="true"} ! regulation of response to biotic stimulus
 is_a: GO:0031347 {is_inferred="true"} ! regulation of defense response
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
-is_a: GO:0050792 {is_inferred="true"} ! regulation of viral process
+is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 
 [Term]
 id: GO:0050696 ! trichloroethylene catabolic process
@@ -44803,7 +44745,6 @@
 id: GO:0051709 ! regulation of killing of cells of other organism
 is_a: GO:0031341 {is_inferred="true"} ! regulation of cell killing
 is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
-is_a: GO:0065008 {is_inferred="true"} ! regulation of biological quality
 
 [Term]
 id: GO:0051710 ! regulation of cytolysis in other organism
@@ -45350,14 +45291,37 @@
 is_a: GO:0010113 {is_inferred="true"} ! negative regulation of systemic acquired resistance
 
 [Term]
+id: GO:0052053 ! negative regulation by symbiont of host catalytic activity
+is_a: GO:0052148 {is_inferred="true"} ! modulation by symbiont of host catalytic activity
+
+[Term]
+id: GO:0052054 ! negative regulation by symbiont of host peptidase activity
+is_a: GO:0052053 {is_inferred="true"} ! negative regulation by symbiont of host catalytic activity
+is_a: GO:0052149 {is_inferred="true"} ! modulation by symbiont of host peptidase activity
+
+[Term]
+id: GO:0052056 ! negative regulation by symbiont of host molecular function
+is_a: GO:0052055 {is_inferred="true"} ! modulation by symbiont of host molecular function
+
+[Term]
 id: GO:0052074 ! positive regulation by symbiont of host salicylic acid-mediated defense response
 is_a: GO:1901672 {is_inferred="true"} ! positive regulation of systemic acquired resistance
 
 [Term]
 id: GO:0052148 ! modulation by symbiont of host catalytic activity
-is_a: GO:0052422 {is_inferred="true"} ! modulation by host of symbiont catalytic activity
+is_a: GO:0052055 {is_inferred="true"} ! modulation by symbiont of host molecular function
 
 [Term]
+id: GO:0052149 ! modulation by symbiont of host peptidase activity
+is_a: GO:0052148 {is_inferred="true"} ! modulation by symbiont of host catalytic activity
+is_a: GO:0052547 {is_inferred="true"} ! regulation of peptidase activity
+
+[Term]
+id: GO:0052199 ! negative regulation of catalytic activity in other organism involved in symbiotic interaction
+is_a: GO:0043086 {is_inferred="true"} ! negative regulation of catalytic activity
+is_a: GO:0052203 {is_inferred="true"} ! modulation of catalytic activity in other organism involved in symbiotic interaction
+
+[Term]
 id: GO:0052314 ! phytoalexin metabolic process
 is_a: GO:0009404 {is_inferred="true"} ! toxin metabolic process
 
@@ -45416,6 +45380,18 @@
 is_a: GO:0044179 {is_inferred="true"} ! hemolysis in other organism
 
 [Term]
+id: GO:0052403 ! negative regulation by host of symbiont catalytic activity
+is_a: GO:0052422 {is_inferred="true"} ! modulation by host of symbiont catalytic activity
+
+[Term]
+id: GO:0052404 ! negative regulation by host of symbiont peptidase activity
+is_a: GO:0052403 {is_inferred="true"} ! negative regulation by host of symbiont catalytic activity
+
+[Term]
+id: GO:0052405 ! negative regulation by host of symbiont molecular function
+is_a: GO:0052428 {is_inferred="true"} ! modulation by host of symbiont molecular function
+
+[Term]
 id: GO:0052409 ! metabolism by organism of cell wall cellulose in other organism involved in symbiotic interaction
 is_a: GO:0044043 {is_inferred="true"} ! multi-organism glucan metabolic process
 
@@ -45425,9 +45401,13 @@
 
 [Term]
 id: GO:0052422 ! modulation by host of symbiont catalytic activity
-is_a: GO:0052055 {is_inferred="true"} ! modulation by symbiont of host molecular function
+is_a: GO:0052428 {is_inferred="true"} ! modulation by host of symbiont molecular function
 
 [Term]
+id: GO:0052427 ! modulation by host of symbiont peptidase activity
+is_a: GO:0052547 {is_inferred="true"} ! regulation of peptidase activity
+
+[Term]
 id: GO:0052543 ! callose deposition in cell wall
 is_a: GO:0052545 {is_inferred="true"} ! callose localization
 
@@ -55063,6 +55043,27 @@
 is_a: GO:0006914 {is_inferred="true"} ! autophagy
 
 [Term]
+id: GO:0075075 ! modulation by host of symbiont adenylate cyclase activity
+is_a: GO:0045761 {is_inferred="true"} ! regulation of adenylate cyclase activity
+is_a: GO:0052422 {is_inferred="true"} ! modulation by host of symbiont catalytic activity
+
+[Term]
+id: GO:0075076 ! positive regulation by host of symbiont adenylate cyclase activity
+is_a: GO:0045762 {is_inferred="true"} ! positive regulation of adenylate cyclase activity
+
+[Term]
+id: GO:0075077 ! negative regulation by host of symbiont adenylate cyclase activity
+is_a: GO:0007194 {is_inferred="true"} ! negative regulation of adenylate cyclase activity
+
+[Term]
+id: GO:0075107 ! positive regulation by symbiont of host adenylate cyclase activity
+is_a: GO:0045762 {is_inferred="true"} ! positive regulation of adenylate cyclase activity
+
+[Term]
+id: GO:0075108 ! negative regulation by symbiont of host adenylate cyclase activity
+is_a: GO:0007194 {is_inferred="true"} ! negative regulation of adenylate cyclase activity
+
+[Term]
 id: GO:0075184 ! regulation of infection cushion formation on or near host
 is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
 is_a: GO:0043903 {is_inferred="true"} ! regulation of symbiosis, encompassing mutualism through parasitism
@@ -55504,21 +55505,6 @@
 is_a: GO:0051169 {is_inferred="true"} ! nuclear transport
 
 [Term]
-id: GO:0075522 ! IRES-dependent viral translational initiation
-is_a: GO:0044033 {is_inferred="true"} ! multi-organism metabolic process
-is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
-
-[Term]
-id: GO:0075523 ! viral translational frameshifting
-is_a: GO:0044034 {is_inferred="true"} ! multi-organism biosynthetic process
-is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
-
-[Term]
-id: GO:0075527 ! viral RNA editing
-is_a: GO:0044033 {is_inferred="true"} ! multi-organism metabolic process
-is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
-
-[Term]
 id: GO:0075733 ! intracellular transport of virus
 is_a: GO:1902583 {is_inferred="true"} ! multi-organism intracellular transport
 
@@ -57479,11 +57465,6 @@
 is_a: GO:0098815 {is_inferred="true"} ! modulation of excitatory postsynaptic potential
 
 [Term]
-id: GO:0090401 ! viral-induced premature senescence
-is_a: GO:0044111 {is_inferred="true"} ! development involved in symbiotic interaction
-is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
-
-[Term]
 id: GO:0090404 ! pollen tube tip
 is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
@@ -58545,23 +58526,19 @@
 
 [Term]
 id: GO:0098003 ! viral tail assembly
-is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
-is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
+is_a: GO:0016032 {is_inferred="true"} ! viral process
 
 [Term]
 id: GO:0098004 ! virus tail fiber assembly
-is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
-is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
+is_a: GO:0016032 {is_inferred="true"} ! viral process
 
 [Term]
 id: GO:0098009 ! viral terminase, large subunit
-is_a: GO:0044815 {is_inferred="true"} ! DNA packaging complex
 is_a: GO:1904949 {is_inferred="true"} ! ATPase complex
 
 [Term]
 id: GO:0098045 ! virus baseplate assembly
-is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
-is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
+is_a: GO:0016032 {is_inferred="true"} ! viral process
 
 [Term]
 id: GO:0098501 ! polynucleotide dephosphorylation
@@ -61171,6 +61148,26 @@
 is_a: GO:0110004 {is_inferred="true"} ! positive regulation of tRNA methylation
 
 [Term]
+id: GO:0110013 ! positive regulation of aggregation involved in sorocarp development
+is_a: GO:0010647 {is_inferred="true"} ! positive regulation of cell communication
+is_a: GO:0032109 {is_inferred="true"} ! positive regulation of response to nutrient levels
+is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
+
+[Term]
+id: GO:0110014 ! negative regulation of aggregation involved in sorocarp development
+is_a: GO:0010648 {is_inferred="true"} ! negative regulation of cell communication
+is_a: GO:0032108 {is_inferred="true"} ! negative regulation of response to nutrient levels
+is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
+
+[Term]
+id: GO:0110015 ! positive regulation of elastin catabolic process
+is_a: GO:0031331 {is_inferred="true"} ! positive regulation of cellular catabolic process
+is_a: GO:0045732 {is_inferred="true"} ! positive regulation of protein catabolic process
+is_a: GO:1903020 {is_inferred="true"} ! positive regulation of glycoprotein metabolic process
+
+[Term]
 id: GO:0120006 ! regulation of glutamatergic neuron differentiation
 is_a: GO:0045664 {is_inferred="true"} ! regulation of neuron differentiation
 
@@ -62500,8 +62497,8 @@
 is_a: GO:0002833 {is_inferred="true"} ! positive regulation of response to biotic stimulus
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
 is_a: GO:0039533 {is_inferred="true"} ! regulation of MDA-5 signaling pathway
+is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:0045089 {is_inferred="true"} ! positive regulation of innate immune response
-is_a: GO:0048524 {is_inferred="true"} ! positive regulation of viral process
 is_a: GO:1902533 {is_inferred="true"} ! positive regulation of intracellular signal transduction
 
 [Term]
@@ -62511,8 +62508,8 @@
 is_a: GO:0002833 {is_inferred="true"} ! positive regulation of response to biotic stimulus
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
 is_a: GO:0039535 {is_inferred="true"} ! regulation of RIG-I signaling pathway
+is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:0045089 {is_inferred="true"} ! positive regulation of innate immune response
-is_a: GO:0048524 {is_inferred="true"} ! positive regulation of viral process
 is_a: GO:1902533 {is_inferred="true"} ! positive regulation of intracellular signal transduction
 
 [Term]
@@ -67661,15 +67658,15 @@
 
 [Term]
 id: GO:1901217 ! regulation of holin activity
-is_a: GO:0001898 {is_inferred="true"} ! regulation of cytolysis by symbiont of host cells
 is_a: GO:0022898 {is_inferred="true"} ! regulation of transmembrane transporter activity
+is_a: GO:0051709 {is_inferred="true"} ! regulation of killing of cells of other organism
 is_a: GO:1902186 {is_inferred="true"} ! regulation of viral release from host cell
 
 [Term]
 id: GO:1901218 ! negative regulation of holin activity
-is_a: GO:0001899 {is_inferred="true"} ! negative regulation of cytolysis by symbiont of host cells
 is_a: GO:0032410 {is_inferred="true"} ! negative regulation of transporter activity
 is_a: GO:0034763 {is_inferred="true"} ! negative regulation of transmembrane transport
+is_a: GO:0051711 {is_inferred="true"} ! negative regulation of killing of cells of other organism
 is_a: GO:1901217 {is_inferred="true"} ! regulation of holin activity
 is_a: GO:1902187 {is_inferred="true"} ! negative regulation of viral release from host cell
 
@@ -74345,12 +74342,6 @@
 is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
 
 [Term]
-id: GO:1902586 ! multi-organism intercellular transport
-is_a: GO:0010496 {is_inferred="true"} ! intercellular transport
-is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
-is_a: GO:0044766 {is_inferred="true"} ! multi-organism transport
-
-[Term]
 id: GO:1902587 ! single-organism plasmodesmata-mediated intercellular transport
 is_a: GO:0010497 {is_inferred="true"} ! plasmodesmata-mediated intercellular transport
 is_a: GO:1902585 {is_inferred="true"} ! single-organism intercellular transport
@@ -74358,7 +74349,8 @@
 [Term]
 id: GO:1902588 ! multi-organism plasmodesmata-mediated intercellular transport
 is_a: GO:0010497 {is_inferred="true"} ! plasmodesmata-mediated intercellular transport
-is_a: GO:1902586 {is_inferred="true"} ! multi-organism intercellular transport
+is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
+is_a: GO:0044766 {is_inferred="true"} ! multi-organism transport
 
 [Term]
 id: GO:1902590 ! multi-organism organelle organization
@@ -74372,12 +74364,6 @@
 is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
 [Term]
-id: GO:1902592 ! multi-organism membrane budding
-is_a: GO:0006900 {is_inferred="true"} ! membrane budding
-is_a: GO:0044803 {is_inferred="true"} ! multi-organism membrane organization
-is_a: GO:1902590 {is_inferred="true"} ! multi-organism organelle organization
-
-[Term]
 id: GO:1902593 ! single-organism nuclear import
 is_a: GO:0051170 {is_inferred="true"} ! nuclear import
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
@@ -79815,23 +79801,15 @@
 
 [Term]
 id: GO:1903772 ! regulation of viral budding via host ESCRT complex
-is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
-is_a: GO:0044087 {is_inferred="true"} ! regulation of cellular component biogenesis
-is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
 is_a: GO:1903900 {is_inferred="true"} ! regulation of viral life cycle
 
 [Term]
 id: GO:1903773 ! negative regulation of viral budding via host ESCRT complex
-is_a: GO:0010639 {is_inferred="true"} ! negative regulation of organelle organization
-is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
 is_a: GO:1903772 {is_inferred="true"} ! regulation of viral budding via host ESCRT complex
 is_a: GO:1903901 {is_inferred="true"} ! negative regulation of viral life cycle
 
 [Term]
 id: GO:1903774 ! positive regulation of viral budding via host ESCRT complex
-is_a: GO:0010638 {is_inferred="true"} ! positive regulation of organelle organization
-is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
-is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
 is_a: GO:1903772 {is_inferred="true"} ! regulation of viral budding via host ESCRT complex
 is_a: GO:1903902 {is_inferred="true"} ! positive regulation of viral life cycle
 
@@ -81791,7 +81769,6 @@
 [Term]
 id: GO:1904187 ! regulation of transformation of host cell by virus
 is_a: GO:0050792 {is_inferred="true"} ! regulation of viral process
-is_a: GO:0065008 {is_inferred="true"} ! regulation of biological quality
 
 [Term]
 id: GO:1904188 ! negative regulation of transformation of host cell by virus
@@ -85626,19 +85603,16 @@
 
 [Term]
 id: GO:1904971 ! regulation of viral translation
-is_a: GO:0006417 {is_inferred="true"} ! regulation of translation
-is_a: GO:1903900 {is_inferred="true"} ! regulation of viral life cycle
+is_a: GO:0050792 {is_inferred="true"} ! regulation of viral process
 
 [Term]
 id: GO:1904972 ! negative regulation of viral translation
-is_a: GO:0017148 {is_inferred="true"} ! negative regulation of translation
-is_a: GO:1903901 {is_inferred="true"} ! negative regulation of viral life cycle
+is_a: GO:0048525 {is_inferred="true"} ! negative regulation of viral process
 is_a: GO:1904971 {is_inferred="true"} ! regulation of viral translation
 
 [Term]
 id: GO:1904973 ! positive regulation of viral translation
-is_a: GO:0045727 {is_inferred="true"} ! positive regulation of translation
-is_a: GO:1903902 {is_inferred="true"} ! positive regulation of viral life cycle
+is_a: GO:0048524 {is_inferred="true"} ! positive regulation of viral process
 is_a: GO:1904971 {is_inferred="true"} ! regulation of viral translation
 
 [Term]
@@ -86470,16 +86444,12 @@
 
 [Term]
 id: GO:1905137 ! regulation of viral DNA genome packaging via site-specific sequence recognition
-is_a: GO:0033044 {is_inferred="true"} ! regulation of chromosome organization
-is_a: GO:0044087 {is_inferred="true"} ! regulation of cellular component biogenesis
 is_a: GO:1903900 {is_inferred="true"} ! regulation of viral life cycle
 
 [Term]
 id: GO:1905138 ! positive regulation of viral DNA genome packaging via site-specific sequence recognition
-is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
 is_a: GO:1903902 {is_inferred="true"} ! positive regulation of viral life cycle
 is_a: GO:1905137 {is_inferred="true"} ! regulation of viral DNA genome packaging via site-specific sequence recognition
-is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
 
 [Term]
 id: GO:1905139 ! apical ectodermal ridge formation
@@ -91495,6 +91465,10 @@
 is_a: GO:0043170 {is_inferred="true"} ! macromolecule metabolic process
 
 [Term]
+id: GO:1990969 ! modulation by host of viral RNA-binding transcription factor activity
+is_a: GO:0052428 {is_inferred="true"} ! modulation by host of symbiont molecular function
+
+[Term]
 id: GO:1990971 ! EMILIN complex
 is_a: GO:0044420 {is_inferred="true"} ! extracellular matrix component
 is_a: GO:0098637 {is_inferred="true"} ! protein complex involved in cell-matrix adhesion
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 41209)
+++ go_inferences.obo	(working copy)
@@ -60896,11 +60896,6 @@
 is_a: GO:0045739 {is_inferred="true"} ! positive regulation of DNA repair
 
 [Term]
-id: GO:0100027 ! regulation of cell separation after cytokinesis by transcription from RNA polymerase II promoter
-is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0010590 {is_inferred="true"} ! regulation of cell separation after cytokinesis
-
-[Term]
 id: GO:0100028 ! regulation of conjugation with cellular fusion by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
 is_a: GO:0031137 {is_inferred="true"} ! regulation of conjugation with cellular fusion
@@ -63317,11 +63312,6 @@
 is_a: GO:0045944 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter
 
 [Term]
-id: GO:1900405 ! regulation of cell separation after cytokinesis by regulation of transcription from RNA polymerase II promoter
-is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
-is_a: GO:0010590 {is_inferred="true"} ! regulation of cell separation after cytokinesis
-
-[Term]
 id: GO:1900406 ! regulation of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter
 is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
 is_a: GO:0031137 {is_inferred="true"} ! regulation of conjugation with cellular fusion
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40993)
+++ go_inferences.obo	(working copy)
@@ -17417,10 +17417,12 @@
 [Term]
 id: GO:0019068 ! virion assembly
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
+is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
 
 [Term]
 id: GO:0019069 ! viral capsid assembly
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
+is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
 
 [Term]
 id: GO:0019073 ! viral DNA genome packaging
@@ -30675,6 +30677,7 @@
 [Term]
 id: GO:0039528 ! cytoplasmic pattern recognition receptor signaling pathway in response to virus
 is_a: GO:0002753 {is_inferred="true"} ! cytoplasmic pattern recognition receptor signaling pathway
+is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
 
 [Term]
 id: GO:0039531 ! regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway
@@ -30726,6 +30729,10 @@
 is_a: GO:0039588 {is_inferred="true"} ! suppression by virus of host antigen processing and presentation
 
 [Term]
+id: GO:0039599 ! cleavage by virus of host mRNA
+is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
+
+[Term]
 id: GO:0039631 ! DNA translocase activity involved in viral DNA genome packaging
 is_a: GO:0015616 {is_inferred="true"} ! DNA translocase activity
 
@@ -30736,6 +30743,7 @@
 [Term]
 id: GO:0039637 ! catabolism by virus of host DNA
 is_a: GO:0044035 {is_inferred="true"} ! multi-organism catabolic process
+is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
 
 [Term]
 id: GO:0039642 ! virion nucleoid
@@ -30769,15 +30777,18 @@
 [Term]
 id: GO:0039693 ! viral DNA genome replication
 is_a: GO:0044034 {is_inferred="true"} ! multi-organism biosynthetic process
+is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
 
 [Term]
 id: GO:0039694 ! viral RNA genome replication
 is_a: GO:0044033 {is_inferred="true"} ! multi-organism metabolic process
+is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
 
 [Term]
 id: GO:0039699 ! viral mRNA cap methylation
 is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
 is_a: GO:0044033 {is_inferred="true"} ! multi-organism metabolic process
+is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
 is_a: GO:1901698 {is_inferred="true"} ! response to nitrogen compound
 
 [Term]
@@ -40578,6 +40589,7 @@
 [Term]
 id: GO:0046773 ! suppression by virus of host translation termination
 is_a: GO:0044034 {is_inferred="true"} ! multi-organism biosynthetic process
+is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
 
 [Term]
 id: GO:0046776 ! suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I
@@ -40597,6 +40609,7 @@
 [Term]
 id: GO:0046807 ! viral scaffold assembly and maintenance
 is_a: GO:0006461 {is_inferred="true"} ! protein complex assembly
+is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
 
 [Term]
 id: GO:0046819 ! protein secretion by the type V secretion system
@@ -41683,13 +41696,11 @@
 [Term]
 id: GO:0048524 ! positive regulation of viral process
 is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
-is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
 is_a: GO:0050792 {is_inferred="true"} ! regulation of viral process
 
 [Term]
 id: GO:0048525 ! negative regulation of viral process
 is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
-is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
 is_a: GO:0050792 {is_inferred="true"} ! regulation of viral process
 
 [Term]
@@ -42704,7 +42715,6 @@
 [Term]
 id: GO:0050792 ! regulation of viral process
 is_a: GO:0043903 {is_inferred="true"} ! regulation of symbiosis, encompassing mutualism through parasitism
-is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
 
 [Term]
 id: GO:0050799 ! cocaine biosynthetic process
@@ -55496,14 +55506,17 @@
 [Term]
 id: GO:0075522 ! IRES-dependent viral translational initiation
 is_a: GO:0044033 {is_inferred="true"} ! multi-organism metabolic process
+is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
 
 [Term]
 id: GO:0075523 ! viral translational frameshifting
 is_a: GO:0044034 {is_inferred="true"} ! multi-organism biosynthetic process
+is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
 
 [Term]
 id: GO:0075527 ! viral RNA editing
 is_a: GO:0044033 {is_inferred="true"} ! multi-organism metabolic process
+is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
 
 [Term]
 id: GO:0075733 ! intracellular transport of virus
@@ -58533,10 +58546,12 @@
 [Term]
 id: GO:0098003 ! viral tail assembly
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
+is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
 
 [Term]
 id: GO:0098004 ! virus tail fiber assembly
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
+is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
 
 [Term]
 id: GO:0098009 ! viral terminase, large subunit
@@ -58546,6 +58561,7 @@
 [Term]
 id: GO:0098045 ! virus baseplate assembly
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
+is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
 
 [Term]
 id: GO:0098501 ! polynucleotide dephosphorylation
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40950)
+++ go_inferences.obo	(working copy)
@@ -266,7 +266,6 @@
 id: GO:0000086 ! G2/M transition of mitotic cell cycle
 is_a: GO:0044772 {is_inferred="true"} ! mitotic cell cycle phase transition
 is_a: GO:0044839 {is_inferred="true"} ! cell cycle G2/M phase transition
-is_a: GO:0045840 {is_inferred="true"} ! positive regulation of mitotic nuclear division
 
 [Term]
 id: GO:0000087 ! mitotic M phase
@@ -8035,6 +8034,10 @@
 is_a: GO:0071174 {is_inferred="true"} ! mitotic spindle checkpoint
 
 [Term]
+id: GO:0007095 ! mitotic G2 DNA damage checkpoint
+is_a: GO:0031572 {is_inferred="true"} ! G2 DNA damage checkpoint
+
+[Term]
 id: GO:0007096 ! regulation of exit from mitosis
 is_a: GO:0007088 {is_inferred="true"} ! regulation of mitotic nuclear division
 
@@ -11594,7 +11597,6 @@
 
 [Term]
 id: GO:0010389 ! regulation of G2/M transition of mitotic cell cycle
-is_a: GO:0007088 {is_inferred="true"} ! regulation of mitotic nuclear division
 is_a: GO:1901990 {is_inferred="true"} ! regulation of mitotic cell cycle phase transition
 is_a: GO:1902749 {is_inferred="true"} ! regulation of cell cycle G2/M phase transition
 
@@ -13324,7 +13326,6 @@
 [Term]
 id: GO:0010971 ! positive regulation of G2/M transition of mitotic cell cycle
 is_a: GO:0010389 {is_inferred="true"} ! regulation of G2/M transition of mitotic cell cycle
-is_a: GO:0045840 {is_inferred="true"} ! positive regulation of mitotic nuclear division
 is_a: GO:1901992 {is_inferred="true"} ! positive regulation of mitotic cell cycle phase transition
 is_a: GO:1902751 {is_inferred="true"} ! positive regulation of cell cycle G2/M phase transition
 
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40949)
+++ go_inferences.obo	(working copy)
@@ -61311,6 +61311,10 @@
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
+id: GO:0140025 ! contractile vacuole tethering involved in discharge
+is_a: GO:0006903 {is_inferred="true"} ! vesicle targeting
+
+[Term]
 id: GO:1900000 ! regulation of anthocyanin catabolic process
 is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
 is_a: GO:0031537 {is_inferred="true"} ! regulation of anthocyanin metabolic process
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40934)
+++ go_inferences.obo	(working copy)
@@ -49324,6 +49324,38 @@
 is_a: GO:0033137 {is_inferred="true"} ! negative regulation of peptidyl-serine phosphorylation
 
 [Term]
+id: GO:0061868 ! hepatic stellate cell migration
+is_a: GO:0010761 {is_inferred="true"} ! fibroblast migration
+
+[Term]
+id: GO:0061869 ! regulation of hepatic stellate cell migration
+is_a: GO:0010762 {is_inferred="true"} ! regulation of fibroblast migration
+
+[Term]
+id: GO:0061870 ! positive regulation of hepatic stellate cell migration
+is_a: GO:0010763 {is_inferred="true"} ! positive regulation of fibroblast migration
+is_a: GO:0061869 {is_inferred="true"} ! regulation of hepatic stellate cell migration
+
+[Term]
+id: GO:0061871 ! negative regulation of hepatic stellate cell migration
+is_a: GO:0010764 {is_inferred="true"} ! negative regulation of fibroblast migration
+is_a: GO:0061869 {is_inferred="true"} ! regulation of hepatic stellate cell migration
+
+[Term]
+id: GO:0061873 ! regulation of hepatic stellate cell contraction
+is_a: GO:1903115 {is_inferred="true"} ! regulation of actin filament-based movement
+
+[Term]
+id: GO:0061874 ! positive regulation of hepatic stellate cell contraction
+is_a: GO:0061873 {is_inferred="true"} ! regulation of hepatic stellate cell contraction
+is_a: GO:1903116 {is_inferred="true"} ! positive regulation of actin filament-based movement
+
+[Term]
+id: GO:0061875 ! negative regulation of hepatic stellate cell contraction
+is_a: GO:0051271 {is_inferred="true"} ! negative regulation of cellular component movement
+is_a: GO:0061873 {is_inferred="true"} ! regulation of hepatic stellate cell contraction
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40931)
+++ go_inferences.obo	(working copy)
@@ -15436,6 +15436,7 @@
 [Term]
 id: GO:0015810 ! aspartate transport
 is_a: GO:0015740 {is_inferred="true"} ! C4-dicarboxylate transport
+is_a: GO:0015800 {is_inferred="true"} ! acidic amino acid transport
 
 [Term]
 id: GO:0015811 ! L-cystine transport
@@ -15451,6 +15452,7 @@
 [Term]
 id: GO:0015813 ! L-glutamate transport
 is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
+is_a: GO:0015800 {is_inferred="true"} ! acidic amino acid transport
 is_a: GO:0015807 {is_inferred="true"} ! L-amino acid transport
 
 [Term]
@@ -45120,16 +45122,17 @@
 
 [Term]
 id: GO:0051936 ! gamma-aminobutyric acid reuptake
+is_a: GO:0015812 {is_inferred="true"} ! gamma-aminobutyric acid transport
 is_a: GO:0051933 {is_inferred="true"} ! amino acid neurotransmitter reuptake
-is_a: GO:0051939 {is_inferred="true"} ! gamma-aminobutyric acid import
 
 [Term]
 id: GO:0051938 ! L-glutamate import
-is_a: GO:0015813 {is_inferred="true"} ! L-glutamate transport
+is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 
 [Term]
 id: GO:0051939 ! gamma-aminobutyric acid import
+is_a: GO:0015800 {is_inferred="true"} ! acidic amino acid transport
 is_a: GO:0015812 {is_inferred="true"} ! gamma-aminobutyric acid transport
 is_a: GO:0043090 {is_inferred="true"} ! amino acid import
 
@@ -48979,7 +48982,8 @@
 
 [Term]
 id: GO:0061528 ! aspartate secretion
-is_a: GO:0015810 {is_inferred="true"} ! aspartate transport
+is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
+is_a: GO:0015740 {is_inferred="true"} ! C4-dicarboxylate transport
 is_a: GO:0046717 {is_inferred="true"} ! acid secretion
 
 [Term]
@@ -50778,13 +50782,13 @@
 
 [Term]
 id: GO:0070777 ! D-aspartate transport
-is_a: GO:0015810 {is_inferred="true"} ! aspartate transport
+is_a: GO:0015740 {is_inferred="true"} ! C4-dicarboxylate transport
 is_a: GO:0042940 {is_inferred="true"} ! D-amino acid transport
 
 [Term]
 id: GO:0070778 ! L-aspartate transport
+is_a: GO:0015740 {is_inferred="true"} ! C4-dicarboxylate transport
 is_a: GO:0015807 {is_inferred="true"} ! L-amino acid transport
-is_a: GO:0015810 {is_inferred="true"} ! aspartate transport
 
 [Term]
 id: GO:0070779 ! D-aspartate import
@@ -55995,10 +55999,11 @@
 
 [Term]
 id: GO:0089704 ! L-glutamate transmembrane export from vacuole
+is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
 is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
 is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
 is_a: GO:0044746 {is_inferred="true"} ! amino acid transmembrane export
-is_a: GO:0089711 {is_inferred="true"} ! L-glutamate transmembrane transport
+is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
 
 [Term]
 id: GO:0089705 ! protein localization to outer membrane
@@ -56034,6 +56039,7 @@
 
 [Term]
 id: GO:0089711 ! L-glutamate transmembrane transport
+is_a: GO:0015813 {is_inferred="true"} ! L-glutamate transport
 is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
 
 [Term]
@@ -57507,7 +57513,7 @@
 
 [Term]
 id: GO:0090453 ! aspartate transmembrane import into vacuole
-is_a: GO:0015810 {is_inferred="true"} ! aspartate transport
+is_a: GO:0015740 {is_inferred="true"} ! C4-dicarboxylate transport
 is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
 is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
 is_a: GO:0044745 {is_inferred="true"} ! amino acid transmembrane import
@@ -57515,7 +57521,8 @@
 [Term]
 id: GO:0090454 ! glutamate transmembrane import into vacuole
 is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
-is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
+is_a: GO:0015800 {is_inferred="true"} ! acidic amino acid transport
+is_a: GO:0032975 {is_inferred="true"} ! amino acid transmembrane import into vacuole
 
 [Term]
 id: GO:0090455 ! ornithine transmembrane import into vacuole
@@ -57656,6 +57663,7 @@
 [Term]
 id: GO:0090515 ! L-glutamate transmembrane import into vacuole
 is_a: GO:0089711 {is_inferred="true"} ! L-glutamate transmembrane transport
+is_a: GO:0090454 {is_inferred="true"} ! glutamate transmembrane import into vacuole
 is_a: GO:1903802 {is_inferred="true"} ! L-glutamate(1-) import across plasma membrane
 
 [Term]
@@ -57666,8 +57674,9 @@
 
 [Term]
 id: GO:0090517 ! L-lysine transmembrane import into vacuole
-is_a: GO:0015819 {is_inferred="true"} ! lysine transport
 is_a: GO:0061461 {is_inferred="true"} ! L-lysine import
+is_a: GO:0090456 {is_inferred="true"} ! lysine transmembrane import into vacuole
+is_a: GO:1903401 {is_inferred="true"} ! L-lysine transmembrane transport
 
 [Term]
 id: GO:0090518 ! L-arginine transmembrane import into vacuole
@@ -59018,8 +59027,8 @@
 
 [Term]
 id: GO:0098712 ! L-glutamate import across plasma membrane
-is_a: GO:0089711 {is_inferred="true"} ! L-glutamate transmembrane transport
 is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
+is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
 is_a: GO:1903802 {is_inferred="true"} ! L-glutamate(1-) import across plasma membrane
 
 [Term]
@@ -66058,17 +66067,16 @@
 
 [Term]
 id: GO:1900920 ! regulation of L-glutamate import
-is_a: GO:0002036 {is_inferred="true"} ! regulation of L-glutamate transport
 is_a: GO:0010958 {is_inferred="true"} ! regulation of amino acid import
 
 [Term]
 id: GO:1900921 ! negative regulation of L-glutamate import
-is_a: GO:0002037 {is_inferred="true"} ! negative regulation of L-glutamate transport
+is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
 is_a: GO:1900920 {is_inferred="true"} ! regulation of L-glutamate import
 
 [Term]
 id: GO:1900922 ! positive regulation of L-glutamate import
-is_a: GO:0002038 {is_inferred="true"} ! positive regulation of L-glutamate transport
+is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
 is_a: GO:1900920 {is_inferred="true"} ! regulation of L-glutamate import
 
 [Term]
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40906)
+++ go_inferences.obo	(working copy)
@@ -40919,6 +40919,7 @@
 
 [Term]
 id: GO:0047496 ! vesicle transport along microtubule
+is_a: GO:0072384 {is_inferred="true"} ! organelle transport along microtubule
 is_a: GO:0099518 {is_inferred="true"} ! vesicle cytoskeletal trafficking
 
 [Term]
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40903)
+++ go_inferences.obo	(working copy)
@@ -299,6 +299,11 @@
 is_a: GO:1901682 {is_inferred="true"} ! sulfur compound transmembrane transporter activity
 
 [Term]
+id: GO:0000100 ! S-methylmethionine transmembrane transporter activity
+is_a: GO:0072349 {is_inferred="true"} ! modified amino acid transmembrane transporter activity
+is_a: GO:1901682 {is_inferred="true"} ! sulfur compound transmembrane transporter activity
+
+[Term]
 id: GO:0000101 ! sulfur amino acid transport
 is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
 is_a: GO:0072348 {is_inferred="true"} ! sulfur compound transport
@@ -4760,6 +4765,7 @@
 [Term]
 id: GO:0005308 ! creatine transmembrane transporter activity
 is_a: GO:0015171 {is_inferred="true"} ! amino acid transmembrane transporter activity
+is_a: GO:0072349 {is_inferred="true"} ! modified amino acid transmembrane transporter activity
 
 [Term]
 id: GO:0005309 ! creatine:sodium symporter activity
@@ -14241,6 +14247,7 @@
 id: GO:0015184 ! L-cystine transmembrane transporter activity
 is_a: GO:0000099 {is_inferred="true"} ! sulfur amino acid transmembrane transporter activity
 is_a: GO:0015179 {is_inferred="true"} ! L-amino acid transmembrane transporter activity
+is_a: GO:0072349 {is_inferred="true"} ! modified amino acid transmembrane transporter activity
 
 [Term]
 id: GO:0015185 ! gamma-aminobutyric acid transmembrane transporter activity
@@ -14418,6 +14425,7 @@
 id: GO:0015233 ! pantothenate transmembrane transporter activity
 is_a: GO:0008028 {is_inferred="true"} ! monocarboxylic acid transmembrane transporter activity
 is_a: GO:0042887 {is_inferred="true"} ! amide transmembrane transporter activity
+is_a: GO:0072349 {is_inferred="true"} ! modified amino acid transmembrane transporter activity
 
 [Term]
 id: GO:0015234 ! thiamine transmembrane transporter activity
@@ -14719,6 +14727,7 @@
 id: GO:0015569 ! p-aminobenzoyl-glutamate transmembrane transporter activity
 is_a: GO:0005310 {is_inferred="true"} ! dicarboxylic acid transmembrane transporter activity
 is_a: GO:0071916 {is_inferred="true"} ! dipeptide transmembrane transporter activity
+is_a: GO:0072349 {is_inferred="true"} ! modified amino acid transmembrane transporter activity
 
 [Term]
 id: GO:0015571 ! N-acetylgalactosamine transmembrane transporter activity
@@ -15401,6 +15410,7 @@
 
 [Term]
 id: GO:0015805 ! S-adenosyl-L-methionine transport
+is_a: GO:0051182 {is_inferred="true"} ! coenzyme transport
 is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 is_a: GO:0072348 {is_inferred="true"} ! sulfur compound transport
 
@@ -15421,6 +15431,7 @@
 [Term]
 id: GO:0015809 ! arginine transport
 is_a: GO:0006812 {is_inferred="true"} ! cation transport
+is_a: GO:0015802 {is_inferred="true"} ! basic amino acid transport
 
 [Term]
 id: GO:0015810 ! aspartate transport
@@ -15456,6 +15467,7 @@
 [Term]
 id: GO:0015817 ! histidine transport
 is_a: GO:0006812 {is_inferred="true"} ! cation transport
+is_a: GO:0015802 {is_inferred="true"} ! basic amino acid transport
 is_a: GO:0045117 {is_inferred="true"} ! azole transport
 
 [Term]
@@ -15466,6 +15478,7 @@
 [Term]
 id: GO:0015819 ! lysine transport
 is_a: GO:0006812 {is_inferred="true"} ! cation transport
+is_a: GO:0015802 {is_inferred="true"} ! basic amino acid transport
 
 [Term]
 id: GO:0015820 ! leucine transport
@@ -15672,6 +15685,7 @@
 [Term]
 id: GO:0015876 ! acetyl-CoA transport
 is_a: GO:0015916 {is_inferred="true"} ! fatty-acyl-CoA transport
+is_a: GO:0051182 {is_inferred="true"} ! coenzyme transport
 
 [Term]
 id: GO:0015877 ! biopterin transport
@@ -15692,6 +15706,7 @@
 id: GO:0015880 ! coenzyme A transport
 is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015868 {is_inferred="true"} ! purine ribonucleotide transport
+is_a: GO:0051182 {is_inferred="true"} ! coenzyme transport
 is_a: GO:0051503 {is_inferred="true"} ! adenine nucleotide transport
 
 [Term]
@@ -15708,6 +15723,7 @@
 id: GO:0015883 ! FAD transport
 is_a: GO:0006862 {is_inferred="true"} ! nucleotide transport
 is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
+is_a: GO:0051182 {is_inferred="true"} ! coenzyme transport
 
 [Term]
 id: GO:0015884 ! folic acid transport
@@ -15731,6 +15747,7 @@
 id: GO:0015887 ! pantothenate transmembrane transport
 is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
 is_a: GO:0042886 {is_inferred="true"} ! amide transport
+is_a: GO:0051182 {is_inferred="true"} ! coenzyme transport
 is_a: GO:0072337 {is_inferred="true"} ! modified amino acid transport
 is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
@@ -25317,13 +25334,11 @@
 [Term]
 id: GO:0032974 ! amino acid transmembrane export from vacuole
 is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
-is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
 is_a: GO:0044746 {is_inferred="true"} ! amino acid transmembrane export
 
 [Term]
 id: GO:0032975 ! amino acid transmembrane import into vacuole
 is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
-is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
 is_a: GO:0044745 {is_inferred="true"} ! amino acid transmembrane import
 
 [Term]
@@ -27641,7 +27656,7 @@
 
 [Term]
 id: GO:0034226 ! lysine import
-is_a: GO:0015819 {is_inferred="true"} ! lysine transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
 is_a: GO:0043090 {is_inferred="true"} ! amino acid import
 
 [Term]
@@ -28106,15 +28121,22 @@
 
 [Term]
 id: GO:0034488 ! basic amino acid transmembrane export from vacuole
-is_a: GO:0015802 {is_inferred="true"} ! basic amino acid transport
-is_a: GO:0032974 {is_inferred="true"} ! amino acid transmembrane export from vacuole
+is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
+is_a: GO:1990822 {is_inferred="true"} ! basic amino acid transmembrane transport
 
 [Term]
 id: GO:0034489 ! neutral amino acid transmembrane export from vacuole
 is_a: GO:0015804 {is_inferred="true"} ! neutral amino acid transport
-is_a: GO:0032974 {is_inferred="true"} ! amino acid transmembrane export from vacuole
+is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
+is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
+is_a: GO:0044746 {is_inferred="true"} ! amino acid transmembrane export
 
 [Term]
+id: GO:0034490 ! basic amino acid transmembrane import into vacuole
+is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
+is_a: GO:1990822 {is_inferred="true"} ! basic amino acid transmembrane transport
+
+[Term]
 id: GO:0034496 ! multivesicular body membrane disassembly
 is_a: GO:0030397 {is_inferred="true"} ! membrane disassembly
 
@@ -28166,6 +28188,10 @@
 is_a: GO:0072337 {is_inferred="true"} ! modified amino acid transport
 
 [Term]
+id: GO:0034590 ! L-hydroxyproline transmembrane transporter activity
+is_a: GO:0072349 {is_inferred="true"} ! modified amino acid transmembrane transporter activity
+
+[Term]
 id: GO:0034592 ! synaptic vesicle lumen
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
 
@@ -28223,6 +28249,7 @@
 is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:0035673 {is_inferred="true"} ! oligopeptide transmembrane transporter activity
 is_a: GO:0042937 {is_inferred="true"} ! tripeptide transporter activity
+is_a: GO:0072349 {is_inferred="true"} ! modified amino acid transmembrane transporter activity
 is_a: GO:1901682 {is_inferred="true"} ! sulfur compound transmembrane transporter activity
 
 [Term]
@@ -28880,18 +28907,18 @@
 
 [Term]
 id: GO:0035348 ! acetyl-CoA transmembrane transport
-is_a: GO:0015876 {is_inferred="true"} ! acetyl-CoA transport
+is_a: GO:0015916 {is_inferred="true"} ! fatty-acyl-CoA transport
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
 id: GO:0035349 ! coenzyme A transmembrane transport
-is_a: GO:0015880 {is_inferred="true"} ! coenzyme A transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0071106 {is_inferred="true"} ! adenosine 3',5'-bisphosphate transmembrane transport
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
 id: GO:0035350 ! FAD transmembrane transport
-is_a: GO:0015883 {is_inferred="true"} ! FAD transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 is_a: GO:1901679 {is_inferred="true"} ! nucleotide transmembrane transport
 
@@ -43476,6 +43503,10 @@
 is_a: GO:0070192 {is_inferred="true"} ! chromosome organization involved in meiotic cell cycle
 
 [Term]
+id: GO:0051182 ! coenzyme transport
+is_a: GO:0051181 {is_inferred="true"} ! cofactor transport
+
+[Term]
 id: GO:0051183 ! vitamin transporter activity
 is_a: GO:0005215 {is_inferred="true"} ! transporter activity
 
@@ -53414,6 +53445,7 @@
 [Term]
 id: GO:0071996 ! glutathione transmembrane import into vacuole
 is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
+is_a: GO:0034775 {is_inferred="true"} ! glutathione transmembrane transport
 
 [Term]
 id: GO:0071998 ! ascospore release from ascus
@@ -54027,6 +54059,10 @@
 is_a: GO:0042493 {is_inferred="true"} ! response to drug
 
 [Term]
+id: GO:0072349 ! modified amino acid transmembrane transporter activity
+is_a: GO:0022857 {is_inferred="true"} ! transmembrane transporter activity
+
+[Term]
 id: GO:0072350 ! tricarboxylic acid metabolic process
 is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 
@@ -55951,12 +55987,16 @@
 
 [Term]
 id: GO:0089703 ! L-aspartate transmembrane export from vacuole
-is_a: GO:0032974 {is_inferred="true"} ! amino acid transmembrane export from vacuole
+is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
+is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
+is_a: GO:0044746 {is_inferred="true"} ! amino acid transmembrane export
 is_a: GO:0089712 {is_inferred="true"} ! L-aspartate transmembrane transport
 
 [Term]
 id: GO:0089704 ! L-glutamate transmembrane export from vacuole
-is_a: GO:0032974 {is_inferred="true"} ! amino acid transmembrane export from vacuole
+is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
+is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
+is_a: GO:0044746 {is_inferred="true"} ! amino acid transmembrane export
 is_a: GO:0089711 {is_inferred="true"} ! L-glutamate transmembrane transport
 
 [Term]
@@ -55966,16 +56006,22 @@
 
 [Term]
 id: GO:0089706 ! L-ornithine transmembrane export from vacuole
-is_a: GO:0032974 {is_inferred="true"} ! amino acid transmembrane export from vacuole
+is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
+is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
+is_a: GO:0044746 {is_inferred="true"} ! amino acid transmembrane export
 is_a: GO:1903352 {is_inferred="true"} ! L-ornithine transmembrane transport
 
 [Term]
 id: GO:0089707 ! L-lysine transmembrane export from vacuole
-is_a: GO:0034488 {is_inferred="true"} ! basic amino acid transmembrane export from vacuole
+is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
+is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
+is_a: GO:0044746 {is_inferred="true"} ! amino acid transmembrane export
 is_a: GO:1903401 {is_inferred="true"} ! L-lysine transmembrane transport
 
 [Term]
 id: GO:0089708 ! L-histidine transmembrane export from vacuole
+is_a: GO:0015817 {is_inferred="true"} ! histidine transport
+is_a: GO:0032974 {is_inferred="true"} ! amino acid transmembrane export from vacuole
 is_a: GO:0034488 {is_inferred="true"} ! basic amino acid transmembrane export from vacuole
 is_a: GO:0089709 {is_inferred="true"} ! L-histidine transmembrane transport
 
@@ -57461,26 +57507,41 @@
 [Term]
 id: GO:0090453 ! aspartate transmembrane import into vacuole
 is_a: GO:0015810 {is_inferred="true"} ! aspartate transport
-is_a: GO:0032975 {is_inferred="true"} ! amino acid transmembrane import into vacuole
+is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
+is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
+is_a: GO:0044745 {is_inferred="true"} ! amino acid transmembrane import
 
 [Term]
 id: GO:0090454 ! glutamate transmembrane import into vacuole
 is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
+is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
 
 [Term]
 id: GO:0090455 ! ornithine transmembrane import into vacuole
+is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
 is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 
 [Term]
 id: GO:0090456 ! lysine transmembrane import into vacuole
+is_a: GO:0015819 {is_inferred="true"} ! lysine transport
+is_a: GO:0032975 {is_inferred="true"} ! amino acid transmembrane import into vacuole
+is_a: GO:0034226 {is_inferred="true"} ! lysine import
+is_a: GO:0034490 {is_inferred="true"} ! basic amino acid transmembrane import into vacuole
 is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 
 [Term]
 id: GO:0090457 ! histidine transmembrane import into vacuole
+is_a: GO:0015817 {is_inferred="true"} ! histidine transport
+is_a: GO:0032975 {is_inferred="true"} ! amino acid transmembrane import into vacuole
+is_a: GO:0034490 {is_inferred="true"} ! basic amino acid transmembrane import into vacuole
+is_a: GO:0090466 {is_inferred="true"} ! histidine import
 is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 
 [Term]
 id: GO:0090458 ! arginine transmembrane import into vacuole
+is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
+is_a: GO:0044745 {is_inferred="true"} ! amino acid transmembrane import
+is_a: GO:0090467 {is_inferred="true"} ! arginine import
 is_a: GO:1903826 {is_inferred="true"} ! arginine transmembrane transport
 
 [Term]
@@ -57505,12 +57566,13 @@
 
 [Term]
 id: GO:0090466 ! histidine import
-is_a: GO:0015817 {is_inferred="true"} ! histidine transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
 is_a: GO:0043090 {is_inferred="true"} ! amino acid import
+is_a: GO:0045117 {is_inferred="true"} ! azole transport
 
 [Term]
 id: GO:0090467 ! arginine import
-is_a: GO:0015809 {is_inferred="true"} ! arginine transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
 is_a: GO:0043090 {is_inferred="true"} ! amino acid import
 
 [Term]
@@ -57581,9 +57643,11 @@
 id: GO:0090513 ! L-histidine transmembrane import into vacuole
 is_a: GO:0061460 {is_inferred="true"} ! L-histidine import
 is_a: GO:0089709 {is_inferred="true"} ! L-histidine transmembrane transport
+is_a: GO:0090457 {is_inferred="true"} ! histidine transmembrane import into vacuole
 
 [Term]
 id: GO:0090514 ! L-tyrosine transmembrane import into vacuole
+is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
 is_a: GO:0036232 {is_inferred="true"} ! L-tyrosine import
 is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
@@ -57601,12 +57665,13 @@
 
 [Term]
 id: GO:0090517 ! L-lysine transmembrane import into vacuole
+is_a: GO:0015819 {is_inferred="true"} ! lysine transport
 is_a: GO:0061461 {is_inferred="true"} ! L-lysine import
-is_a: GO:1903401 {is_inferred="true"} ! L-lysine transmembrane transport
 
 [Term]
 id: GO:0090518 ! L-arginine transmembrane import into vacuole
 is_a: GO:0043091 {is_inferred="true"} ! L-arginine import
+is_a: GO:0090458 {is_inferred="true"} ! arginine transmembrane import into vacuole
 is_a: GO:1903400 {is_inferred="true"} ! L-arginine transmembrane transport
 
 [Term]
@@ -58979,9 +59044,9 @@
 
 [Term]
 id: GO:0098717 ! pantothenate import across plasma membrane
-is_a: GO:0015887 {is_inferred="true"} ! pantothenate transmembrane transport
 is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
 is_a: GO:1901688 {is_inferred="true"} ! pantothenate import
+is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
 id: GO:0098718 ! serine import across plasma membrane
@@ -59207,6 +59272,7 @@
 id: GO:0098829 ! intestinal folate absorption
 is_a: GO:0015884 {is_inferred="true"} ! folic acid transport
 is_a: GO:0044707 {is_inferred="true"} ! single-multicellular organism process
+is_a: GO:0050892 {is_inferred="true"} ! intestinal absorption
 
 [Term]
 id: GO:0098830 ! presynaptic endosome
@@ -71238,7 +71304,6 @@
 id: GO:1901962 ! S-adenosyl-L-methionine transmembrane transport
 is_a: GO:0015805 {is_inferred="true"} ! S-adenosyl-L-methionine transport
 is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
-is_a: GO:0072337 {is_inferred="true"} ! modified amino acid transport
 
 [Term]
 id: GO:1901963 ! regulation of cell proliferation involved in outflow tract morphogenesis
@@ -71539,18 +71604,19 @@
 
 [Term]
 id: GO:1902022 ! L-lysine transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
 is_a: GO:0015807 {is_inferred="true"} ! L-amino acid transport
-is_a: GO:0015819 {is_inferred="true"} ! lysine transport
 
 [Term]
 id: GO:1902023 ! L-arginine transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
 is_a: GO:0015807 {is_inferred="true"} ! L-amino acid transport
-is_a: GO:0015809 {is_inferred="true"} ! arginine transport
 
 [Term]
 id: GO:1902024 ! L-histidine transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
 is_a: GO:0015807 {is_inferred="true"} ! L-amino acid transport
-is_a: GO:0015817 {is_inferred="true"} ! histidine transport
+is_a: GO:0045117 {is_inferred="true"} ! azole transport
 
 [Term]
 id: GO:1902025 ! nitrate import
@@ -77961,9 +78027,9 @@
 
 [Term]
 id: GO:1903400 ! L-arginine transmembrane transport
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 is_a: GO:1902023 {is_inferred="true"} ! L-arginine transport
 is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
-is_a: GO:1903826 {is_inferred="true"} ! arginine transmembrane transport
 
 [Term]
 id: GO:1903401 ! L-lysine transmembrane transport
@@ -79963,9 +80029,9 @@
 
 [Term]
 id: GO:1903826 ! arginine transmembrane transport
-is_a: GO:0003333 {is_inferred="true"} ! amino acid transmembrane transport
 is_a: GO:0015809 {is_inferred="true"} ! arginine transport
 is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
+is_a: GO:1990822 {is_inferred="true"} ! basic amino acid transmembrane transport
 
 [Term]
 id: GO:1903827 ! regulation of cellular protein localization
@@ -90895,7 +90961,7 @@
 
 [Term]
 id: GO:1990543 ! mitochondrial S-adenosyl-L-methionine transmembrane transport
-is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
+is_a: GO:1901962 {is_inferred="true"} ! S-adenosyl-L-methionine transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
@@ -91026,6 +91092,7 @@
 [Term]
 id: GO:1990591 ! asparagine transmembrane import into vacuole
 is_a: GO:0032975 {is_inferred="true"} ! amino acid transmembrane import into vacuole
+is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
 is_a: GO:0090469 {is_inferred="true"} ! asparagine import
 is_a: GO:1903713 {is_inferred="true"} ! asparagine transmembrane transport
 
@@ -91250,6 +91317,7 @@
 
 [Term]
 id: GO:1990818 ! L-arginine transmembrane export from vacuole
+is_a: GO:0032974 {is_inferred="true"} ! amino acid transmembrane export from vacuole
 is_a: GO:1903400 {is_inferred="true"} ! L-arginine transmembrane transport
 
 [Term]
@@ -91260,6 +91328,7 @@
 [Term]
 id: GO:1990822 ! basic amino acid transmembrane transport
 is_a: GO:0003333 {is_inferred="true"} ! amino acid transmembrane transport
+is_a: GO:0015802 {is_inferred="true"} ! basic amino acid transport
 
 [Term]
 id: GO:1990849 ! maintenance of vacuolar location
------------------------------------------------------------------------
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changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

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changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

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changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40891)
+++ go_inferences.obo	(working copy)
@@ -4551,7 +4551,7 @@
 
 [Term]
 id: GO:0003399 ! cytoneme morphogenesis
-is_a: GO:0048858 {is_inferred="true"} ! cell projection morphogenesis
+is_a: GO:0120039 {is_inferred="true"} ! plasma membrane bounded cell projection morphogenesis
 
 [Term]
 id: GO:0003400 ! regulation of COPII vesicle coating
@@ -13340,8 +13340,8 @@
 
 [Term]
 id: GO:0010975 ! regulation of neuron projection development
-is_a: GO:0031344 {is_inferred="true"} ! regulation of cell projection organization
 is_a: GO:0045664 {is_inferred="true"} ! regulation of neuron differentiation
+is_a: GO:0120035 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:0010976 ! positive regulation of neuron projection development
@@ -21498,6 +21498,10 @@
 is_a: GO:0031170 {is_inferred="true"} ! ferricrocin metabolic process
 
 [Term]
+id: GO:0031175 ! neuron projection development
+is_a: GO:0120036 {is_inferred="true"} ! plasma membrane bounded cell projection organization
+
+[Term]
 id: GO:0031177 ! phosphopantetheine binding
 is_a: GO:0033218 {is_inferred="true"} ! amide binding
 is_a: GO:0043168 {is_inferred="true"} ! anion binding
@@ -42106,7 +42110,7 @@
 
 [Term]
 id: GO:0048812 ! neuron projection morphogenesis
-is_a: GO:0048858 {is_inferred="true"} ! cell projection morphogenesis
+is_a: GO:0120039 {is_inferred="true"} ! plasma membrane bounded cell projection morphogenesis
 
 [Term]
 id: GO:0048813 ! dendrite morphogenesis
@@ -45947,8 +45951,8 @@
 is_a: GO:0002066 {is_inferred="true"} ! columnar/cuboidal epithelial cell development
 
 [Term]
-id: GO:0060121 ! vestibular receptor cell stereocilium organization
-is_a: GO:0120036 {is_inferred="true"} ! plasma membrane bounded cell projection organization
+id: GO:0060122 ! inner ear receptor stereocilium organization
+is_a: GO:0031175 {is_inferred="true"} ! neuron projection development
 
 [Term]
 id: GO:0060123 ! regulation of growth hormone secretion
@@ -47993,6 +47997,7 @@
 
 [Term]
 id: GO:0060997 ! dendritic spine morphogenesis
+is_a: GO:0031175 {is_inferred="true"} ! neuron projection development
 is_a: GO:0048812 {is_inferred="true"} ! neuron projection morphogenesis
 
 [Term]
@@ -48013,7 +48018,6 @@
 id: GO:0061001 ! regulation of dendritic spine morphogenesis
 is_a: GO:0048814 {is_inferred="true"} ! regulation of dendrite morphogenesis
 is_a: GO:0060998 {is_inferred="true"} ! regulation of dendritic spine development
-is_a: GO:0120035 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:0061002 ! negative regulation of dendritic spine morphogenesis
@@ -54528,7 +54532,7 @@
 
 [Term]
 id: GO:0072673 ! lamellipodium morphogenesis
-is_a: GO:0048858 {is_inferred="true"} ! cell projection morphogenesis
+is_a: GO:0120039 {is_inferred="true"} ! plasma membrane bounded cell projection morphogenesis
 
 [Term]
 id: GO:0072677 ! eosinophil migration
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40886)
+++ go_inferences.obo	(working copy)
@@ -61009,6 +61009,21 @@
 is_a: GO:1904776 {is_inferred="true"} ! regulation of protein localization to cell cortex
 
 [Term]
+id: GO:0106014 ! regulation of inflammatory response to wounding
+is_a: GO:0050727 {is_inferred="true"} ! regulation of inflammatory response
+is_a: GO:1903034 {is_inferred="true"} ! regulation of response to wounding
+
+[Term]
+id: GO:0106015 ! negative regulation of inflammatory response to wounding
+is_a: GO:0050728 {is_inferred="true"} ! negative regulation of inflammatory response
+is_a: GO:1903035 {is_inferred="true"} ! negative regulation of response to wounding
+
+[Term]
+id: GO:0106016 ! positive regulation of inflammatory response to wounding
+is_a: GO:0050729 {is_inferred="true"} ! positive regulation of inflammatory response
+is_a: GO:1903036 {is_inferred="true"} ! positive regulation of response to wounding
+
+[Term]
 id: GO:0110001 ! toxin-antitoxin complex
 is_a: GO:0005667 {is_inferred="true"} ! transcription factor complex
 is_a: GO:0017053 {is_inferred="true"} ! transcriptional repressor complex
@@ -83661,21 +83676,21 @@
 
 [Term]
 id: GO:1904596 ! regulation of connective tissue replacement involved in inflammatory response wound healing
-is_a: GO:0050727 {is_inferred="true"} ! regulation of inflammatory response
 is_a: GO:0061041 {is_inferred="true"} ! regulation of wound healing
+is_a: GO:0106014 {is_inferred="true"} ! regulation of inflammatory response to wounding
 is_a: GO:1905203 {is_inferred="true"} ! regulation of connective tissue replacement
 
 [Term]
 id: GO:1904597 ! negative regulation of connective tissue replacement involved in inflammatory response wound healing
-is_a: GO:0050728 {is_inferred="true"} ! negative regulation of inflammatory response
 is_a: GO:0061045 {is_inferred="true"} ! negative regulation of wound healing
+is_a: GO:0106015 {is_inferred="true"} ! negative regulation of inflammatory response to wounding
 is_a: GO:1904596 {is_inferred="true"} ! regulation of connective tissue replacement involved in inflammatory response wound healing
 is_a: GO:1905204 {is_inferred="true"} ! negative regulation of connective tissue replacement
 
 [Term]
 id: GO:1904598 ! positive regulation of connective tissue replacement involved in inflammatory response wound healing
-is_a: GO:0050729 {is_inferred="true"} ! positive regulation of inflammatory response
 is_a: GO:0090303 {is_inferred="true"} ! positive regulation of wound healing
+is_a: GO:0106016 {is_inferred="true"} ! positive regulation of inflammatory response to wounding
 is_a: GO:1904596 {is_inferred="true"} ! regulation of connective tissue replacement involved in inflammatory response wound healing
 is_a: GO:1905205 {is_inferred="true"} ! positive regulation of connective tissue replacement
 
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40884)
+++ go_inferences.obo	(working copy)
@@ -1263,6 +1263,10 @@
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
 
 [Term]
+id: GO:0001400 ! mating projection base
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
+
+[Term]
 id: GO:0001401 ! mitochondrial sorting and assembly machinery complex
 is_a: GO:0098799 {is_inferred="true"} ! outer mitochondrial membrane protein complex
 
@@ -7865,6 +7869,7 @@
 id: GO:0007027 ! negative regulation of axonemal microtubule depolymerization
 is_a: GO:0007026 {is_inferred="true"} ! negative regulation of microtubule depolymerization
 is_a: GO:0031345 {is_inferred="true"} ! negative regulation of cell projection organization
+is_a: GO:0120035 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:0007028 ! cytoplasm organization
@@ -16090,10 +16095,12 @@
 [Term]
 id: GO:0016027 ! inaD signaling complex
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0016029 ! subrhabdomeral cisterna
 is_a: GO:0098827 {is_inferred="true"} ! endoplasmic reticulum subcompartment
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0016031 ! tRNA import into mitochondrion
@@ -19745,6 +19752,10 @@
 is_a: GO:0099095 {is_inferred="true"} ! ligand-gated anion channel activity
 
 [Term]
+id: GO:0022857 ! transmembrane transporter activity
+is_a: GO:0005215 {is_inferred="true"} ! transporter activity
+
+[Term]
 id: GO:0022858 ! alanine transmembrane transporter activity
 is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
 
@@ -20292,6 +20303,7 @@
 [Term]
 id: GO:0030426 ! growth cone
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0030446 ! hyphal cell wall
@@ -21571,7 +21583,7 @@
 
 [Term]
 id: GO:0031268 ! pseudopodium organization
-is_a: GO:0030030 {is_inferred="true"} ! cell projection organization
+is_a: GO:0120036 {is_inferred="true"} ! plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:0031269 ! pseudopodium assembly
@@ -22112,7 +22124,7 @@
 
 [Term]
 id: GO:0031529 ! ruffle organization
-is_a: GO:0030030 {is_inferred="true"} ! cell projection organization
+is_a: GO:0120036 {is_inferred="true"} ! plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:0031536 ! positive regulation of exit from mitosis
@@ -22199,7 +22211,7 @@
 [Term]
 id: GO:0031563 ! mating projection tip polarisome
 is_a: GO:0000133 {is_inferred="true"} ! polarisome
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0031567 ! mitotic cell size control checkpoint
@@ -22994,7 +23006,7 @@
 [Term]
 id: GO:0032162 ! mating projection septin band
 is_a: GO:0032158 {is_inferred="true"} ! septin band
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0032168 ! hyphal septin ring
@@ -23019,7 +23031,7 @@
 [Term]
 id: GO:0032175 ! mating projection septin ring
 is_a: GO:0005940 {is_inferred="true"} ! septin ring
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0032177 ! cellular bud neck split septin rings
@@ -23690,7 +23702,7 @@
 
 [Term]
 id: GO:0032420 ! stereocilium
-is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0043005 {is_inferred="true"} ! neuron projection
 
 [Term]
 id: GO:0032421 ! stereocilium bundle
@@ -23713,8 +23725,8 @@
 [Term]
 id: GO:0032426 ! stereocilium tip
 is_a: GO:0044422 {is_inferred="true"} ! organelle part
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0032429 ! regulation of phospholipase A2 activity
@@ -23726,6 +23738,10 @@
 is_a: GO:0032429 {is_inferred="true"} ! regulation of phospholipase A2 activity
 
 [Term]
+id: GO:0032433 ! filopodium tip
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
+
+[Term]
 id: GO:0032434 ! regulation of proteasomal ubiquitin-dependent protein catabolic process
 is_a: GO:0061136 {is_inferred="true"} ! regulation of proteasomal protein catabolic process
 
@@ -23896,11 +23912,11 @@
 
 [Term]
 id: GO:0032528 ! microvillus organization
-is_a: GO:0030030 {is_inferred="true"} ! cell projection organization
+is_a: GO:0120036 {is_inferred="true"} ! plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:0032530 ! regulation of microvillus organization
-is_a: GO:0031344 {is_inferred="true"} ! regulation of cell projection organization
+is_a: GO:0120035 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:0032531 ! regulation of follicle cell microvillus organization
@@ -24752,7 +24768,7 @@
 
 [Term]
 id: GO:0032796 ! uropod organization
-is_a: GO:0030030 {is_inferred="true"} ! cell projection organization
+is_a: GO:0120036 {is_inferred="true"} ! plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:0032803 ! regulation of low-density lipoprotein particle receptor catabolic process
@@ -24922,6 +24938,10 @@
 is_a: GO:0048856 {is_inferred="true"} ! anatomical structure development
 
 [Term]
+id: GO:0032838 ! cell projection cytoplasm
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
+
+[Term]
 id: GO:0032839 ! dendrite cytoplasm
 is_a: GO:0032838 {is_inferred="true"} ! cell projection cytoplasm
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
@@ -26070,6 +26090,10 @@
 is_a: GO:0019829 {is_inferred="true"} ! cation-transporting ATPase activity
 
 [Term]
+id: GO:0033267 ! axon part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
+
+[Term]
 id: GO:0033271 ! myo-inositol phosphate transport
 is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015748 {is_inferred="true"} ! organophosphate ester transport
@@ -28792,6 +28816,10 @@
 is_a: GO:0030182 {is_inferred="true"} ! neuron differentiation
 
 [Term]
+id: GO:0035316 ! non-sensory hair organization
+is_a: GO:0120036 {is_inferred="true"} ! plasma membrane bounded cell projection organization
+
+[Term]
 id: GO:0035322 ! mesenchymal cell migration involved in limb bud formation
 is_a: GO:0090497 {is_inferred="true"} ! mesenchymal cell migration
 
@@ -29368,6 +29396,10 @@
 is_a: GO:0120025 {is_inferred="true"} ! plasma membrane bounded cell projection
 
 [Term]
+id: GO:0035619 ! root hair tip
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
+
+[Term]
 id: GO:0035622 ! intrahepatic bile duct development
 is_a: GO:0061009 {is_inferred="true"} ! common bile duct development
 
@@ -29895,7 +29927,7 @@
 
 [Term]
 id: GO:0035996 ! rhabdomere microvillus
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0035998 ! 7,8-dihydroneopterin 3'-triphosphate biosynthetic process
@@ -32798,6 +32830,10 @@
 is_a: GO:0042999 {is_inferred="true"} ! regulation of Golgi to plasma membrane CFTR protein transport
 
 [Term]
+id: GO:0043005 ! neuron projection
+is_a: GO:0120025 {is_inferred="true"} ! plasma membrane bounded cell projection
+
+[Term]
 id: GO:0043011 ! myeloid dendritic cell differentiation
 is_a: GO:0097028 {is_inferred="true"} ! dendritic cell differentiation
 
@@ -33075,8 +33111,13 @@
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
 [Term]
+id: GO:0043197 ! dendritic spine
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
+
+[Term]
 id: GO:0043198 ! dendritic shaft
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0043199 ! sulfate binding
@@ -33390,7 +33431,7 @@
 [Term]
 id: GO:0043332 ! mating projection tip
 is_a: GO:0030427 {is_inferred="true"} ! site of polarized growth
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0043370 ! regulation of CD4-positive, alpha-beta T cell differentiation
@@ -34508,14 +34549,17 @@
 [Term]
 id: GO:0044292 ! dendrite terminus
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0044306 ! neuron projection terminus
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0044307 ! dendritic branch
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0044319 ! wound healing, spreading of cells
@@ -34525,11 +34569,13 @@
 id: GO:0044326 ! dendritic spine neck
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0044327 ! dendritic spine head
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0044328 ! canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration
@@ -34658,6 +34704,10 @@
 is_a: GO:0044433 {is_inferred="true"} ! cytoplasmic vesicle part
 
 [Term]
+id: GO:0044441 ! ciliary part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
+
+[Term]
 id: GO:0044443 ! pilus part
 is_a: GO:0044463 {is_inferred="true"} ! cell projection part
 
@@ -45849,7 +45899,7 @@
 
 [Term]
 id: GO:0060091 ! kinocilium
-is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0043005 {is_inferred="true"} ! neuron projection
 
 [Term]
 id: GO:0060092 ! regulation of synaptic transmission, glycinergic
@@ -45897,6 +45947,10 @@
 is_a: GO:0002066 {is_inferred="true"} ! columnar/cuboidal epithelial cell development
 
 [Term]
+id: GO:0060121 ! vestibular receptor cell stereocilium organization
+is_a: GO:0120036 {is_inferred="true"} ! plasma membrane bounded cell projection organization
+
+[Term]
 id: GO:0060123 ! regulation of growth hormone secretion
 is_a: GO:0090276 {is_inferred="true"} ! regulation of peptide hormone secretion
 
@@ -45989,8 +46043,7 @@
 
 [Term]
 id: GO:0060171 ! stereocilium membrane
-is_a: GO:0031253 {is_inferred="true"} ! cell projection membrane
-is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0032589 {is_inferred="true"} ! neuron projection membrane
 
 [Term]
 id: GO:0060176 ! regulation of aggregation involved in sorocarp development
@@ -47960,6 +48013,7 @@
 id: GO:0061001 ! regulation of dendritic spine morphogenesis
 is_a: GO:0048814 {is_inferred="true"} ! regulation of dendrite morphogenesis
 is_a: GO:0060998 {is_inferred="true"} ! regulation of dendritic spine development
+is_a: GO:0120035 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:0061002 ! negative regulation of dendritic spine morphogenesis
@@ -48778,7 +48832,7 @@
 
 [Term]
 id: GO:0061455 ! integral component of muscle cell projection membrane
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0061456 ! mesenchymal stem cell migration involved in uteric bud morphogenesis
@@ -49178,6 +49232,7 @@
 [Term]
 id: GO:0061845 ! neuron projection branch point
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0061846 ! dendritic spine cytoplasm
@@ -49191,13 +49246,13 @@
 [Term]
 id: GO:0061850 ! growth cone leading edge
 is_a: GO:0031252 {is_inferred="true"} ! cell leading edge
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0061851 ! leading edge of lamellipodium
 is_a: GO:0031252 {is_inferred="true"} ! cell leading edge
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0061853 ! regulation of neuroblast migration
@@ -50549,6 +50604,10 @@
 is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
 [Term]
+id: GO:0070687 ! macropinocytic cup cytoskeleton
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
+
+[Term]
 id: GO:0070689 ! L-threonine catabolic process to propionate
 is_a: GO:0019541 {is_inferred="true"} ! propionate metabolic process
 
@@ -50887,6 +50946,10 @@
 is_a: GO:0090316 {is_inferred="true"} ! positive regulation of intracellular protein transport
 
 [Term]
+id: GO:0070867 ! mating projection tip membrane
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
+
+[Term]
 id: GO:0070868 ! heterochromatin organization involved in chromatin silencing
 is_a: GO:0070828 {is_inferred="true"} ! heterochromatin organization
 is_a: GO:0097549 {is_inferred="true"} ! chromatin organization involved in negative regulation of transcription
@@ -52683,6 +52746,7 @@
 [Term]
 id: GO:0071598 ! neuronal ribonucleoprotein granule
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0071599 ! otic vesicle development
@@ -57317,6 +57381,10 @@
 is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
 
 [Term]
+id: GO:0090404 ! pollen tube tip
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
+
+[Term]
 id: GO:0090406 ! pollen tube
 is_a: GO:0120025 {is_inferred="true"} ! plasma membrane bounded cell projection
 
@@ -57634,6 +57702,10 @@
 is_a: GO:0003002 {is_inferred="true"} ! regionalization
 
 [Term]
+id: GO:0090723 ! growth cone part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
+
+[Term]
 id: GO:0090730 ! Las1 complex
 is_a: GO:0044445 {is_inferred="true"} ! cytosolic part
 
@@ -57717,7 +57789,7 @@
 
 [Term]
 id: GO:0097061 ! dendritic spine organization
-is_a: GO:0030030 {is_inferred="true"} ! cell projection organization
+is_a: GO:0120036 {is_inferred="true"} ! plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:0097066 ! response to thyroid hormone
@@ -58163,7 +58235,7 @@
 [Term]
 id: GO:0097444 ! spine apparatus
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0097445 ! presynaptic active zone dense projection
@@ -58228,6 +58300,10 @@
 is_a: GO:1902578 {is_inferred="true"} ! single-organism localization
 
 [Term]
+id: GO:0097581 ! lamellipodium organization
+is_a: GO:0120036 {is_inferred="true"} ! plasma membrane bounded cell projection organization
+
+[Term]
 id: GO:0097606 ! positive regulation of nuclear envelope permeability
 is_a: GO:0046824 {is_inferred="true"} ! positive regulation of nucleocytoplasmic transport
 
@@ -58317,6 +58393,10 @@
 is_a: GO:0043229 {is_inferred="true"} ! intracellular organelle
 
 [Term]
+id: GO:0097733 ! photoreceptor cell cilium
+is_a: GO:0043005 {is_inferred="true"} ! neuron projection
+
+[Term]
 id: GO:0097740 ! paraflagellar rod
 is_a: GO:0044441 {is_inferred="true"} ! ciliary part
 
@@ -59148,9 +59228,9 @@
 
 [Term]
 id: GO:0098836 ! cytoskeleton of dendritic spine
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
 is_a: GO:0099571 {is_inferred="true"} ! postsynaptic cytoskeleton
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0098837 ! postsynaptic recycling endosome
@@ -59214,7 +59294,8 @@
 
 [Term]
 id: GO:0098859 ! actin filament bundle of actin-based cell projection
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
+is_a: GO:0097518 {is_inferred="true"} ! parallel actin filament bundle
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0098860 ! actin filament bundle of stereocilium
@@ -59340,10 +59421,10 @@
 [Term]
 id: GO:0098897 ! spine apparatus membrane
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
 is_a: GO:0098588 {is_inferred="true"} ! bounding membrane of organelle
 is_a: GO:0098805 {is_inferred="true"} ! whole membrane
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0098898 ! dense core granule lumen
@@ -59352,9 +59433,9 @@
 [Term]
 id: GO:0098899 ! spine apparatus lumen
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
 is_a: GO:0060205 {is_inferred="true"} ! cytoplasmic vesicle lumen
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0098900 ! regulation of action potential
@@ -59465,8 +59546,8 @@
 id: GO:0098929 ! extrinsic component of spine apparatus membrane
 is_a: GO:0031312 {is_inferred="true"} ! extrinsic component of organelle membrane
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0098930 ! axonal transport
@@ -59564,8 +59645,8 @@
 id: GO:0098952 ! intrinsic component of spine apparatus membrane
 is_a: GO:0031300 {is_inferred="true"} ! intrinsic component of organelle membrane
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:0098953 ! receptor diffusion trapping
@@ -61047,10 +61128,12 @@
 [Term]
 id: GO:0120031 ! plasma membrane bounded cell projection assembly
 is_a: GO:0030031 {is_inferred="true"} ! cell projection assembly
+is_a: GO:0120036 {is_inferred="true"} ! plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly
 is_a: GO:0060491 {is_inferred="true"} ! regulation of cell projection assembly
+is_a: GO:0120035 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly
@@ -61064,6 +61147,10 @@
 is_a: GO:0120032 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection assembly
 
 [Term]
+id: GO:0120036 ! plasma membrane bounded cell projection organization
+is_a: GO:0030030 {is_inferred="true"} ! cell projection organization
+
+[Term]
 id: GO:0140009 ! L-aspartate import across plasma membrane
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 is_a: GO:0089712 {is_inferred="true"} ! L-aspartate transmembrane transport
@@ -69223,6 +69310,10 @@
 is_a: GO:2001259 {is_inferred="true"} ! positive regulation of cation channel activity
 
 [Term]
+id: GO:1901588 ! dendritic microtubule
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
+
+[Term]
 id: GO:1901589 ! axon microtubule bundle
 is_a: GO:0033267 {is_inferred="true"} ! axon part
 is_a: GO:0097427 {is_inferred="true"} ! microtubule bundle
@@ -71128,6 +71219,7 @@
 id: GO:1901962 ! S-adenosyl-L-methionine transmembrane transport
 is_a: GO:0015805 {is_inferred="true"} ! S-adenosyl-L-methionine transport
 is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
+is_a: GO:0072337 {is_inferred="true"} ! modified amino acid transport
 
 [Term]
 id: GO:1901963 ! regulation of cell proliferation involved in outflow tract morphogenesis
@@ -74817,8 +74909,8 @@
 [Term]
 id: GO:1902737 ! dendritic filopodium
 is_a: GO:0030175 {is_inferred="true"} ! filopodium
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
-is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0043005 {is_inferred="true"} ! neuron projection
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:1902739 ! regulation of interferon-alpha secretion
@@ -74843,7 +74935,7 @@
 
 [Term]
 id: GO:1902743 ! regulation of lamellipodium organization
-is_a: GO:0031344 {is_inferred="true"} ! regulation of cell projection organization
+is_a: GO:0120035 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:1902744 ! negative regulation of lamellipodium organization
@@ -75828,7 +75920,7 @@
 
 [Term]
 id: GO:1902950 ! regulation of dendritic spine maintenance
-is_a: GO:0031344 {is_inferred="true"} ! regulation of cell projection organization
+is_a: GO:0120035 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:1902951 ! negative regulation of dendritic spine maintenance
@@ -89318,10 +89410,10 @@
 
 [Term]
 id: GO:1905796 ! regulation of intraciliary anterograde transport
-is_a: GO:0031344 {is_inferred="true"} ! regulation of cell projection organization
 is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
 is_a: GO:0033157 {is_inferred="true"} ! regulation of intracellular protein transport
 is_a: GO:0060632 {is_inferred="true"} ! regulation of microtubule-based movement
+is_a: GO:0120035 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:1905797 ! negative regulation of intraciliary anterograde transport
@@ -89341,10 +89433,10 @@
 
 [Term]
 id: GO:1905799 ! regulation of intraciliary retrograde transport
-is_a: GO:0031344 {is_inferred="true"} ! regulation of cell projection organization
 is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
 is_a: GO:0033157 {is_inferred="true"} ! regulation of intracellular protein transport
 is_a: GO:0060632 {is_inferred="true"} ! regulation of microtubule-based movement
+is_a: GO:0120035 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:1905800 ! negative regulation of intraciliary retrograde transport
@@ -89680,7 +89772,7 @@
 
 [Term]
 id: GO:1905863 ! invadopodium organization
-is_a: GO:0030030 {is_inferred="true"} ! cell projection organization
+is_a: GO:0120036 {is_inferred="true"} ! plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:1905864 ! regulation of ATG1/ULK1 kinase complex assembly
@@ -90006,7 +90098,7 @@
 
 [Term]
 id: GO:1905927 ! regulation of invadopodium disassembly
-is_a: GO:0031344 {is_inferred="true"} ! regulation of cell projection organization
+is_a: GO:0120035 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection organization
 
 [Term]
 id: GO:1905928 ! negative regulation of invadopodium disassembly
@@ -90719,8 +90811,8 @@
 
 [Term]
 id: GO:1990503 ! dendritic lamellar body
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:1990504 ! dense core granule exocytosis
@@ -90963,6 +91055,7 @@
 [Term]
 id: GO:1990635 ! proximal dendrite
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:1990658 ! transnitrosylase complex
@@ -91070,6 +91163,10 @@
 is_a: GO:0031134 {is_inferred="true"} ! sister chromatid biorientation
 
 [Term]
+id: GO:1990761 ! growth cone lamellipodium
+is_a: GO:0043005 {is_inferred="true"} ! neuron projection
+
+[Term]
 id: GO:1990771 ! clathrin-dependent extracellular exosome endocytosis
 is_a: GO:0051650 {is_inferred="true"} ! establishment of vesicle localization
 is_a: GO:0072583 {is_inferred="true"} ! clathrin-dependent endocytosis
@@ -91081,8 +91178,8 @@
 [Term]
 id: GO:1990780 ! cytoplasmic side of dendritic spine plasma membrane
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:1990784 ! response to dsDNA
@@ -91129,6 +91226,10 @@
 is_a: GO:1902850 {is_inferred="true"} ! microtubule cytoskeleton organization involved in mitosis
 
 [Term]
+id: GO:1990812 ! growth cone filopodium
+is_a: GO:0043005 {is_inferred="true"} ! neuron projection
+
+[Term]
 id: GO:1990818 ! L-arginine transmembrane export from vacuole
 is_a: GO:1903400 {is_inferred="true"} ! L-arginine transmembrane transport
 
@@ -91135,6 +91236,7 @@
 [Term]
 id: GO:1990819 ! actin fusion focus
 is_a: GO:0044430 {is_inferred="true"} ! cytoskeletal part
+is_a: GO:0120038 {is_inferred="true"} ! plasma membrane bounded cell projection part
 
 [Term]
 id: GO:1990822 ! basic amino acid transmembrane transport
@@ -91200,6 +91302,10 @@
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
+id: GO:1990906 ! accessory outer segment
+is_a: GO:0043005 {is_inferred="true"} ! neuron projection
+
+[Term]
 id: GO:1990913 ! sperm head plasma membrane
 is_a: GO:0097223 {is_inferred="true"} ! sperm part
 is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40857)
+++ go_inferences.obo	(working copy)
@@ -60923,6 +60923,11 @@
 is_a: GO:0044445 {is_inferred="true"} ! cytosolic part
 
 [Term]
+id: GO:0106011 ! regulation of protein localization to medial cortex
+is_a: GO:1901900 {is_inferred="true"} ! regulation of protein localization to cell division site
+is_a: GO:1904776 {is_inferred="true"} ! regulation of protein localization to cell cortex
+
+[Term]
 id: GO:0110001 ! toxin-antitoxin complex
 is_a: GO:0005667 {is_inferred="true"} ! transcription factor complex
 is_a: GO:0017053 {is_inferred="true"} ! transcriptional repressor complex
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40843)
+++ go_inferences.obo	(working copy)
@@ -241,7 +241,6 @@
 
 [Term]
 id: GO:0000066 ! mitochondrial ornithine transport
-is_a: GO:0006839 {is_inferred="true"} ! mitochondrial transport
 is_a: GO:0015822 {is_inferred="true"} ! ornithine transport
 
 [Term]
@@ -7642,7 +7641,7 @@
 
 [Term]
 id: GO:0006839 ! mitochondrial transport
-is_a: GO:0006810 {is_inferred="true"} ! transport
+is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
 
 [Term]
 id: GO:0006842 ! tricarboxylic acid transport
@@ -7650,7 +7649,6 @@
 
 [Term]
 id: GO:0006843 ! mitochondrial citrate transport
-is_a: GO:0006839 {is_inferred="true"} ! mitochondrial transport
 is_a: GO:0015746 {is_inferred="true"} ! citrate transport
 
 [Term]
@@ -7666,6 +7664,10 @@
 is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
 
 [Term]
+id: GO:0006850 ! mitochondrial pyruvate transport
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
+
+[Term]
 id: GO:0006851 ! mitochondrial calcium ion transmembrane transport
 is_a: GO:0070588 {is_inferred="true"} ! calcium ion transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
@@ -7769,10 +7771,6 @@
 is_a: GO:0016482 {is_inferred="true"} ! cytosolic transport
 
 [Term]
-id: GO:0006896 ! Golgi to vacuole transport
-is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
-
-[Term]
 id: GO:0006904 ! vesicle docking involved in exocytosis
 is_a: GO:0048278 {is_inferred="true"} ! vesicle docking
 
@@ -7894,11 +7892,11 @@
 
 [Term]
 id: GO:0007034 ! vacuolar transport
-is_a: GO:0006810 {is_inferred="true"} ! transport
+is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
 
 [Term]
 id: GO:0007038 ! endocytosed protein transport to vacuole
-is_a: GO:0015031 {is_inferred="true"} ! protein transport
+is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 
 [Term]
 id: GO:0007040 ! lysosome organization
@@ -8641,7 +8639,6 @@
 id: GO:0008333 ! endosome to lysosome transport
 is_a: GO:0007041 {is_inferred="true"} ! lysosomal transport
 is_a: GO:0016197 {is_inferred="true"} ! endosomal transport
-is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
 
 [Term]
 id: GO:0008335 ! female germline ring canal stabilization
@@ -16099,6 +16096,10 @@
 is_a: GO:0098827 {is_inferred="true"} ! endoplasmic reticulum subcompartment
 
 [Term]
+id: GO:0016031 ! tRNA import into mitochondrion
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
+
+[Term]
 id: GO:0016042 ! lipid catabolic process
 is_a: GO:0006629 {is_inferred="true"} ! lipid metabolic process
 is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
@@ -16487,7 +16488,7 @@
 
 [Term]
 id: GO:0016197 ! endosomal transport
-is_a: GO:0006810 {is_inferred="true"} ! transport
+is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
 
 [Term]
 id: GO:0016202 ! regulation of striated muscle tissue development
@@ -19941,6 +19942,7 @@
 
 [Term]
 id: GO:0030150 ! protein import into mitochondrial matrix
+is_a: GO:0006839 {is_inferred="true"} ! mitochondrial transport
 is_a: GO:0072655 {is_inferred="true"} ! establishment of protein localization to mitochondrion
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
@@ -23862,7 +23864,7 @@
 is_a: GO:0045185 {is_inferred="true"} ! maintenance of protein location
 
 [Term]
-id: GO:0032510 ! endosome to lysosome transport via multivesicular body sorting pathway
+id: GO:0032509 ! endosome transport via multivesicular body sorting pathway
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
@@ -25290,11 +25292,13 @@
 
 [Term]
 id: GO:0032974 ! amino acid transmembrane export from vacuole
+is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
 is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
 is_a: GO:0044746 {is_inferred="true"} ! amino acid transmembrane export
 
 [Term]
 id: GO:0032975 ! amino acid transmembrane import into vacuole
+is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
 is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
 is_a: GO:0044745 {is_inferred="true"} ! amino acid transmembrane import
 
@@ -28071,7 +28075,6 @@
 [Term]
 id: GO:0034487 ! vacuolar amino acid transmembrane transport
 is_a: GO:0003333 {is_inferred="true"} ! amino acid transmembrane transport
-is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
 
 [Term]
 id: GO:0034488 ! basic amino acid transmembrane export from vacuole
@@ -29727,6 +29730,7 @@
 [Term]
 id: GO:0035928 ! rRNA import into mitochondrion
 is_a: GO:0051029 {is_inferred="true"} ! rRNA transport
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:0035934 ! corticosterone secretion
@@ -33373,7 +33377,6 @@
 [Term]
 id: GO:0043328 ! protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
 is_a: GO:0006623 {is_inferred="true"} ! protein targeting to vacuole
-is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:0043329 ! protein targeting to membrane involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
@@ -33931,7 +33934,7 @@
 
 [Term]
 id: GO:0043574 ! peroxisomal transport
-is_a: GO:0006810 {is_inferred="true"} ! transport
+is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
 
 [Term]
 id: GO:0043579 ! elaioplast organization
@@ -35049,6 +35052,7 @@
 
 [Term]
 id: GO:0045022 ! early endosome to late endosome transport
+is_a: GO:0016197 {is_inferred="true"} ! endosomal transport
 is_a: GO:0016482 {is_inferred="true"} ! cytosolic transport
 is_a: GO:0098927 {is_inferred="true"} ! vesicle-mediated transport between endosomal compartments
 
@@ -35066,6 +35070,7 @@
 
 [Term]
 id: GO:0045039 ! protein import into mitochondrial inner membrane
+is_a: GO:0006839 {is_inferred="true"} ! mitochondrial transport
 is_a: GO:0044743 {is_inferred="true"} ! protein transmembrane import into intracellular organelle
 is_a: GO:0090151 {is_inferred="true"} ! establishment of protein localization to mitochondrial membrane
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
@@ -35072,11 +35077,13 @@
 
 [Term]
 id: GO:0045040 ! protein import into mitochondrial outer membrane
+is_a: GO:0006839 {is_inferred="true"} ! mitochondrial transport
 is_a: GO:0090151 {is_inferred="true"} ! establishment of protein localization to mitochondrial membrane
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:0045041 ! protein import into mitochondrial intermembrane space
+is_a: GO:0006839 {is_inferred="true"} ! mitochondrial transport
 is_a: GO:0072655 {is_inferred="true"} ! establishment of protein localization to mitochondrion
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
@@ -41146,10 +41153,6 @@
 is_a: GO:0048214 {is_inferred="true"} ! regulation of Golgi vesicle fusion to target membrane
 
 [Term]
-id: GO:0048227 ! plasma membrane to endosome transport
-is_a: GO:0016197 {is_inferred="true"} ! endosomal transport
-
-[Term]
 id: GO:0048235 ! pollen sperm cell differentiation
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 
@@ -41187,7 +41190,6 @@
 [Term]
 id: GO:0048250 ! mitochondrial iron ion transport
 is_a: GO:0006826 {is_inferred="true"} ! iron ion transport
-is_a: GO:0006839 {is_inferred="true"} ! mitochondrial transport
 
 [Term]
 id: GO:0048252 ! lauric acid metabolic process
@@ -43393,6 +43395,10 @@
 is_a: GO:1901135 {is_inferred="true"} ! carbohydrate derivative metabolic process
 
 [Term]
+id: GO:0051169 ! nuclear transport
+is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
+
+[Term]
 id: GO:0051174 ! regulation of phosphorus metabolic process
 is_a: GO:0031323 {is_inferred="true"} ! regulation of cellular metabolic process
 
@@ -48850,6 +48856,7 @@
 
 [Term]
 id: GO:0061502 ! early endosome to recycling endosome transport
+is_a: GO:0016197 {is_inferred="true"} ! endosomal transport
 is_a: GO:0016482 {is_inferred="true"} ! cytosolic transport
 is_a: GO:0098927 {is_inferred="true"} ! vesicle-mediated transport between endosomal compartments
 
@@ -49092,7 +49099,6 @@
 
 [Term]
 id: GO:0061741 ! chaperone-mediated protein transport involved in chaperone-mediated autophagy
-is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
 
 [Term]
@@ -57262,7 +57268,7 @@
 
 [Term]
 id: GO:0090374 ! oligopeptide export from mitochondrion
-is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
+is_a: GO:0035672 {is_inferred="true"} ! oligopeptide transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
@@ -57560,6 +57566,10 @@
 is_a: GO:0098533 {is_inferred="true"} ! ATPase dependent transmembrane transport complex
 
 [Term]
+id: GO:0090539 ! peptide pheromone export by transmembrane transport
+is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
+
+[Term]
 id: GO:0090554 ! phosphatidylcholine-translocating ATPase activity
 is_a: GO:0004012 {is_inferred="true"} ! phospholipid-translocating ATPase activity
 is_a: GO:0008525 {is_inferred="true"} ! phosphatidylcholine transporter activity
@@ -59452,10 +59462,6 @@
 is_a: GO:0099555 {is_inferred="true"} ! trans-synaptic signaling by nitric oxide, modulating synaptic transmission
 
 [Term]
-id: GO:0098927 ! vesicle-mediated transport between endosomal compartments
-is_a: GO:0016197 {is_inferred="true"} ! endosomal transport
-
-[Term]
 id: GO:0098929 ! extrinsic component of spine apparatus membrane
 is_a: GO:0031312 {is_inferred="true"} ! extrinsic component of organelle membrane
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
@@ -59967,17 +59973,16 @@
 
 [Term]
 id: GO:0099074 ! mitochondrion to lysosome transport
+is_a: GO:0006839 {is_inferred="true"} ! mitochondrial transport
 is_a: GO:0007041 {is_inferred="true"} ! lysosomal transport
 is_a: GO:0099075 {is_inferred="true"} ! mitochondrion-derived vesicle mediated transport
 
 [Term]
 id: GO:0099075 ! mitochondrion-derived vesicle mediated transport
-is_a: GO:0006839 {is_inferred="true"} ! mitochondrial transport
 is_a: GO:0016192 {is_inferred="true"} ! vesicle-mediated transport
 
 [Term]
 id: GO:0099076 ! mitochondrion to peroxisome transport
-is_a: GO:0043574 {is_inferred="true"} ! peroxisomal transport
 is_a: GO:0099075 {is_inferred="true"} ! mitochondrion-derived vesicle mediated transport
 
 [Term]
@@ -60032,7 +60037,7 @@
 [Term]
 id: GO:0099093 ! mitochondrial calcium release
 is_a: GO:0006851 {is_inferred="true"} ! mitochondrial calcium ion transmembrane transport
-is_a: GO:0051209 {is_inferred="true"} ! release of sequestered calcium ion into cytosol
+is_a: GO:0097553 {is_inferred="true"} ! calcium ion transmembrane import into cytosol
 is_a: GO:1901660 {is_inferred="true"} ! calcium ion export
 
 [Term]
@@ -60267,10 +60272,6 @@
 is_a: GO:0098960 {is_inferred="true"} ! postsynaptic neurotransmitter receptor activity
 
 [Term]
-id: GO:0099532 ! synaptic vesicle endosomal processing
-is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
-
-[Term]
 id: GO:0099533 ! positive regulation of presynaptic cytosolic calcium concentration
 is_a: GO:0007204 {is_inferred="true"} ! positive regulation of cytosolic calcium ion concentration
 is_a: GO:0099509 {is_inferred="true"} ! regulation of presynaptic cytosolic calcium ion concentration
@@ -60420,10 +60421,6 @@
 is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 
 [Term]
-id: GO:0099592 ! endocytosed synaptic vesicle processing via endosome
-is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
-
-[Term]
 id: GO:0099601 ! regulation of neurotransmitter receptor activity
 is_a: GO:0010469 {is_inferred="true"} ! regulation of receptor activity
 
@@ -60507,9 +60504,9 @@
 
 [Term]
 id: GO:0099638 ! endosome to plasma membrane protein transport
-is_a: GO:0015031 {is_inferred="true"} ! protein transport
-is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
+is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0090002 {is_inferred="true"} ! establishment of protein localization to plasma membrane
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 is_a: GO:1990126 {is_inferred="true"} ! retrograde transport, endosome to plasma membrane
 
 [Term]
@@ -60545,6 +60542,7 @@
 
 [Term]
 id: GO:0099646 ! neurotransmitter receptor transport, plasma membrane to endosome
+is_a: GO:0016197 {is_inferred="true"} ! endosomal transport
 is_a: GO:0036010 {is_inferred="true"} ! protein localization to endosome
 is_a: GO:0072594 {is_inferred="true"} ! establishment of protein localization to organelle
 
@@ -66496,14 +66494,14 @@
 [Term]
 id: GO:1901028 ! regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
 is_a: GO:0010821 {is_inferred="true"} ! regulation of mitochondrion organization
+is_a: GO:0032386 {is_inferred="true"} ! regulation of intracellular transport
 is_a: GO:0046902 {is_inferred="true"} ! regulation of mitochondrial membrane permeability
-is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
 is_a: GO:2001233 {is_inferred="true"} ! regulation of apoptotic signaling pathway
 
 [Term]
 id: GO:1901029 ! negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
 is_a: GO:0010823 {is_inferred="true"} ! negative regulation of mitochondrion organization
-is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
+is_a: GO:0032387 {is_inferred="true"} ! negative regulation of intracellular transport
 is_a: GO:1901028 {is_inferred="true"} ! regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
 is_a: GO:2001234 {is_inferred="true"} ! negative regulation of apoptotic signaling pathway
 
@@ -66510,7 +66508,7 @@
 [Term]
 id: GO:1901030 ! positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
 is_a: GO:0010822 {is_inferred="true"} ! positive regulation of mitochondrion organization
-is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
+is_a: GO:0032388 {is_inferred="true"} ! positive regulation of intracellular transport
 is_a: GO:1901028 {is_inferred="true"} ! regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
 is_a: GO:2001235 {is_inferred="true"} ! positive regulation of apoptotic signaling pathway
 
@@ -71137,7 +71135,7 @@
 
 [Term]
 id: GO:1901965 ! endoplasmic reticulum to chloroplast transport
-is_a: GO:0006810 {is_inferred="true"} ! transport
+is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
 
 [Term]
 id: GO:1901966 ! regulation of cellular response to iron ion starvation
@@ -72974,6 +72972,7 @@
 
 [Term]
 id: GO:1902334 ! fructose export from vacuole to cytoplasm
+is_a: GO:0007034 {is_inferred="true"} ! vacuolar transport
 is_a: GO:0015755 {is_inferred="true"} ! fructose transport
 is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
@@ -74976,7 +74975,7 @@
 
 [Term]
 id: GO:1902774 ! late endosome to lysosome transport
-is_a: GO:0007041 {is_inferred="true"} ! lysosomal transport
+is_a: GO:0008333 {is_inferred="true"} ! endosome to lysosome transport
 is_a: GO:0045324 {is_inferred="true"} ! late endosome to vacuole transport
 
 [Term]
@@ -77512,16 +77511,16 @@
 
 [Term]
 id: GO:1903335 ! regulation of vacuolar transport
-is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
+is_a: GO:0032386 {is_inferred="true"} ! regulation of intracellular transport
 
 [Term]
 id: GO:1903336 ! negative regulation of vacuolar transport
-is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
+is_a: GO:0032387 {is_inferred="true"} ! negative regulation of intracellular transport
 is_a: GO:1903335 {is_inferred="true"} ! regulation of vacuolar transport
 
 [Term]
 id: GO:1903337 ! positive regulation of vacuolar transport
-is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
+is_a: GO:0032388 {is_inferred="true"} ! positive regulation of intracellular transport
 is_a: GO:1903335 {is_inferred="true"} ! regulation of vacuolar transport
 
 [Term]
@@ -77921,7 +77920,6 @@
 
 [Term]
 id: GO:1903415 ! flavonoid transport from endoplasmic reticulum to plant-type vacuole
-is_a: GO:0007034 {is_inferred="true"} ! vacuolar transport
 is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 
 [Term]
@@ -79732,7 +79730,7 @@
 is_a: GO:2000637 {is_inferred="true"} ! positive regulation of gene silencing by miRNA
 
 [Term]
-id: GO:1903801 ! L-leucine import across membrane
+id: GO:1903801 ! L-leucine import across plasma membrane
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 is_a: GO:0098713 {is_inferred="true"} ! leucine import across plasma membrane
 is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
@@ -85123,23 +85121,31 @@
 [Term]
 id: GO:1904916 ! transmembrane L-lysine transport from lysosomal lumen to cytosol
 is_a: GO:0007041 {is_inferred="true"} ! lysosomal transport
+is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 is_a: GO:1903401 {is_inferred="true"} ! L-lysine transmembrane transport
 
 [Term]
 id: GO:1904917 ! transmembrane L-arginine transport from lysosomal lumen to cytosol
 is_a: GO:0007041 {is_inferred="true"} ! lysosomal transport
+is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 is_a: GO:1903400 {is_inferred="true"} ! L-arginine transmembrane transport
 
 [Term]
 id: GO:1904918 ! transmembrane L-histidine transport from lysosomal lumen to cytosol
 is_a: GO:0007041 {is_inferred="true"} ! lysosomal transport
+is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
 is_a: GO:0089709 {is_inferred="true"} ! L-histidine transmembrane transport
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:1904919 ! transmembrane L-cystine transport from lysosomal lumen to cytosol
 is_a: GO:0007041 {is_inferred="true"} ! lysosomal transport
 is_a: GO:0015811 {is_inferred="true"} ! L-cystine transport
+is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
 is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:1904920 ! regulation of MAPK cascade involved in axon regeneration
@@ -85267,8 +85273,10 @@
 
 [Term]
 id: GO:1904947 ! folic acid import into mitochondrion
-is_a: GO:0006839 {is_inferred="true"} ! mitochondrial transport
 is_a: GO:0015884 {is_inferred="true"} ! folic acid transport
+is_a: GO:0035461 {is_inferred="true"} ! vitamin transmembrane transport
+is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
+is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1904948 ! midbrain dopaminergic neuron differentiation
@@ -89071,20 +89079,20 @@
 
 [Term]
 id: GO:1905749 ! regulation of endosome to plasma membrane protein transport
-is_a: GO:0051223 {is_inferred="true"} ! regulation of protein transport
+is_a: GO:0033157 {is_inferred="true"} ! regulation of intracellular protein transport
 is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
 is_a: GO:0090003 {is_inferred="true"} ! regulation of establishment of protein localization to plasma membrane
 
 [Term]
 id: GO:1905750 ! negative regulation of endosome to plasma membrane protein transport
-is_a: GO:0051224 {is_inferred="true"} ! negative regulation of protein transport
 is_a: GO:0090005 {is_inferred="true"} ! negative regulation of establishment of protein localization to plasma membrane
+is_a: GO:0090317 {is_inferred="true"} ! negative regulation of intracellular protein transport
 is_a: GO:1905749 {is_inferred="true"} ! regulation of endosome to plasma membrane protein transport
 
 [Term]
 id: GO:1905751 ! positive regulation of endosome to plasma membrane protein transport
-is_a: GO:0051222 {is_inferred="true"} ! positive regulation of protein transport
 is_a: GO:0090004 {is_inferred="true"} ! positive regulation of establishment of protein localization to plasma membrane
+is_a: GO:0090316 {is_inferred="true"} ! positive regulation of intracellular protein transport
 is_a: GO:1905749 {is_inferred="true"} ! regulation of endosome to plasma membrane protein transport
 
 [Term]
@@ -90767,11 +90775,11 @@
 
 [Term]
 id: GO:1990542 ! mitochondrial transmembrane transport
-is_a: GO:0006839 {is_inferred="true"} ! mitochondrial transport
 is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
 
 [Term]
 id: GO:1990543 ! mitochondrial S-adenosyl-L-methionine transmembrane transport
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
@@ -90844,6 +90852,7 @@
 
 [Term]
 id: GO:1990557 ! mitochondrial sulfate transmembrane transport
+is_a: GO:1902358 {is_inferred="true"} ! sulfate transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
@@ -96703,16 +96712,17 @@
 
 [Term]
 id: GO:2001135 ! regulation of endocytic recycling
+is_a: GO:0032386 {is_inferred="true"} ! regulation of intracellular transport
 is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
 
 [Term]
 id: GO:2001136 ! negative regulation of endocytic recycling
-is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
+is_a: GO:0032387 {is_inferred="true"} ! negative regulation of intracellular transport
 is_a: GO:2001135 {is_inferred="true"} ! regulation of endocytic recycling
 
 [Term]
 id: GO:2001137 ! positive regulation of endocytic recycling
-is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
+is_a: GO:0032388 {is_inferred="true"} ! positive regulation of intracellular transport
 is_a: GO:2001135 {is_inferred="true"} ! regulation of endocytic recycling
 
 [Term]
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

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changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40831)
+++ go_inferences.obo	(working copy)
@@ -22209,7 +22209,7 @@
 is_a: GO:2000134 {is_inferred="true"} ! negative regulation of G1/S transition of mitotic cell cycle
 
 [Term]
-id: GO:0031569 ! G2 cell size control checkpoint
+id: GO:0031569 ! mitotic G2 cell size control checkpoint
 is_a: GO:0010972 {is_inferred="true"} ! negative regulation of G2/M transition of mitotic cell cycle
 is_a: GO:0031567 {is_inferred="true"} ! mitotic cell size control checkpoint
 
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40818)
+++ go_inferences.obo	(working copy)
@@ -11998,18 +11998,19 @@
 
 [Term]
 id: GO:0010591 ! regulation of lamellipodium assembly
-is_a: GO:0060491 {is_inferred="true"} ! regulation of cell projection assembly
+is_a: GO:0120032 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection assembly
 is_a: GO:1902743 {is_inferred="true"} ! regulation of lamellipodium organization
 
 [Term]
 id: GO:0010592 ! positive regulation of lamellipodium assembly
 is_a: GO:0010591 {is_inferred="true"} ! regulation of lamellipodium assembly
-is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
+is_a: GO:0120034 {is_inferred="true"} ! positive regulation of plasma membrane bounded cell projection assembly
 is_a: GO:1902745 {is_inferred="true"} ! positive regulation of lamellipodium organization
 
 [Term]
 id: GO:0010593 ! negative regulation of lamellipodium assembly
 is_a: GO:0010591 {is_inferred="true"} ! regulation of lamellipodium assembly
+is_a: GO:0120033 {is_inferred="true"} ! negative regulation of plasma membrane bounded cell projection assembly
 is_a: GO:1902744 {is_inferred="true"} ! negative regulation of lamellipodium organization
 
 [Term]
@@ -21576,18 +21577,17 @@
 
 [Term]
 id: GO:0031272 ! regulation of pseudopodium assembly
-is_a: GO:0060491 {is_inferred="true"} ! regulation of cell projection assembly
+is_a: GO:0120032 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:0031273 ! negative regulation of pseudopodium assembly
 is_a: GO:0031272 {is_inferred="true"} ! regulation of pseudopodium assembly
-is_a: GO:0031345 {is_inferred="true"} ! negative regulation of cell projection organization
+is_a: GO:0120033 {is_inferred="true"} ! negative regulation of plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:0031274 ! positive regulation of pseudopodium assembly
 is_a: GO:0031272 {is_inferred="true"} ! regulation of pseudopodium assembly
-is_a: GO:0031346 {is_inferred="true"} ! positive regulation of cell projection organization
-is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
+is_a: GO:0120034 {is_inferred="true"} ! positive regulation of plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:0031275 ! regulation of lateral pseudopodium assembly
@@ -21836,7 +21836,7 @@
 
 [Term]
 id: GO:0031383 ! regulation of mating projection assembly
-is_a: GO:0060491 {is_inferred="true"} ! regulation of cell projection assembly
+is_a: GO:0120032 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection assembly
 is_a: GO:1905708 {is_inferred="true"} ! regulation of cell morphogenesis involved in conjugation with cellular fusion
 
 [Term]
@@ -23911,7 +23911,7 @@
 [Term]
 id: GO:0032534 ! regulation of microvillus assembly
 is_a: GO:0032530 {is_inferred="true"} ! regulation of microvillus organization
-is_a: GO:0060491 {is_inferred="true"} ! regulation of cell projection assembly
+is_a: GO:0120032 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:0032538 ! regulation of host-seeking behavior
@@ -36971,7 +36971,7 @@
 
 [Term]
 id: GO:0045724 ! positive regulation of cilium assembly
-is_a: GO:0031346 {is_inferred="true"} ! positive regulation of cell projection organization
+is_a: GO:0120034 {is_inferred="true"} ! positive regulation of plasma membrane bounded cell projection assembly
 is_a: GO:1902017 {is_inferred="true"} ! regulation of cilium assembly
 is_a: GO:1902117 {is_inferred="true"} ! positive regulation of organelle assembly
 
@@ -44093,18 +44093,17 @@
 
 [Term]
 id: GO:0051489 ! regulation of filopodium assembly
-is_a: GO:0060491 {is_inferred="true"} ! regulation of cell projection assembly
+is_a: GO:0120032 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:0051490 ! negative regulation of filopodium assembly
-is_a: GO:0031345 {is_inferred="true"} ! negative regulation of cell projection organization
 is_a: GO:0051489 {is_inferred="true"} ! regulation of filopodium assembly
+is_a: GO:0120033 {is_inferred="true"} ! negative regulation of plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:0051491 ! positive regulation of filopodium assembly
-is_a: GO:0031346 {is_inferred="true"} ! positive regulation of cell projection organization
-is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
 is_a: GO:0051489 {is_inferred="true"} ! regulation of filopodium assembly
+is_a: GO:0120034 {is_inferred="true"} ! positive regulation of plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:0051492 ! regulation of stress fiber assembly
@@ -61047,6 +61046,21 @@
 is_a: GO:0030031 {is_inferred="true"} ! cell projection assembly
 
 [Term]
+id: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly
+is_a: GO:0060491 {is_inferred="true"} ! regulation of cell projection assembly
+
+[Term]
+id: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly
+is_a: GO:0031345 {is_inferred="true"} ! negative regulation of cell projection organization
+is_a: GO:0120032 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection assembly
+
+[Term]
+id: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly
+is_a: GO:0031346 {is_inferred="true"} ! positive regulation of cell projection organization
+is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
+is_a: GO:0120032 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection assembly
+
+[Term]
 id: GO:0140009 ! L-aspartate import across plasma membrane
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 is_a: GO:0089712 {is_inferred="true"} ! L-aspartate transmembrane transport
@@ -61209,17 +61223,16 @@
 
 [Term]
 id: GO:1900027 ! regulation of ruffle assembly
-is_a: GO:0060491 {is_inferred="true"} ! regulation of cell projection assembly
+is_a: GO:0120032 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:1900028 ! negative regulation of ruffle assembly
-is_a: GO:0031345 {is_inferred="true"} ! negative regulation of cell projection organization
+is_a: GO:0120033 {is_inferred="true"} ! negative regulation of plasma membrane bounded cell projection assembly
 is_a: GO:1900027 {is_inferred="true"} ! regulation of ruffle assembly
 
 [Term]
 id: GO:1900029 ! positive regulation of ruffle assembly
-is_a: GO:0031346 {is_inferred="true"} ! positive regulation of cell projection organization
-is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
+is_a: GO:0120034 {is_inferred="true"} ! positive regulation of plasma membrane bounded cell projection assembly
 is_a: GO:1900027 {is_inferred="true"} ! regulation of ruffle assembly
 
 [Term]
@@ -71388,12 +71401,12 @@
 
 [Term]
 id: GO:1902017 ! regulation of cilium assembly
-is_a: GO:0060491 {is_inferred="true"} ! regulation of cell projection assembly
+is_a: GO:0120032 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection assembly
 is_a: GO:1902115 {is_inferred="true"} ! regulation of organelle assembly
 
 [Term]
 id: GO:1902018 ! negative regulation of cilium assembly
-is_a: GO:0031345 {is_inferred="true"} ! negative regulation of cell projection organization
+is_a: GO:0120033 {is_inferred="true"} ! negative regulation of plasma membrane bounded cell projection assembly
 is_a: GO:1902017 {is_inferred="true"} ! regulation of cilium assembly
 is_a: GO:1902116 {is_inferred="true"} ! negative regulation of organelle assembly
 
@@ -75646,11 +75659,10 @@
 [Term]
 id: GO:1902917 ! positive regulation of mating projection assembly
 is_a: GO:0031139 {is_inferred="true"} ! positive regulation of conjugation with cellular fusion
-is_a: GO:0031346 {is_inferred="true"} ! positive regulation of cell projection organization
 is_a: GO:0031383 {is_inferred="true"} ! regulation of mating projection assembly
-is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
 is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
 is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
+is_a: GO:0120034 {is_inferred="true"} ! positive regulation of plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:1902918 ! poly(5-hydroxyvalerate) metabolic process
@@ -79248,14 +79260,13 @@
 
 [Term]
 id: GO:1903697 ! negative regulation of microvillus assembly
-is_a: GO:0031345 {is_inferred="true"} ! negative regulation of cell projection organization
 is_a: GO:0032534 {is_inferred="true"} ! regulation of microvillus assembly
+is_a: GO:0120033 {is_inferred="true"} ! negative regulation of plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:1903698 ! positive regulation of microvillus assembly
-is_a: GO:0031346 {is_inferred="true"} ! positive regulation of cell projection organization
 is_a: GO:0032534 {is_inferred="true"} ! regulation of microvillus assembly
-is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
+is_a: GO:0120034 {is_inferred="true"} ! positive regulation of plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:1903699 ! tarsal gland development
@@ -81463,17 +81474,16 @@
 
 [Term]
 id: GO:1904170 ! regulation of bleb assembly
-is_a: GO:0060491 {is_inferred="true"} ! regulation of cell projection assembly
+is_a: GO:0120032 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:1904171 ! negative regulation of bleb assembly
-is_a: GO:0031345 {is_inferred="true"} ! negative regulation of cell projection organization
+is_a: GO:0120033 {is_inferred="true"} ! negative regulation of plasma membrane bounded cell projection assembly
 is_a: GO:1904170 {is_inferred="true"} ! regulation of bleb assembly
 
 [Term]
 id: GO:1904172 ! positive regulation of bleb assembly
-is_a: GO:0031346 {is_inferred="true"} ! positive regulation of cell projection organization
-is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
+is_a: GO:0120034 {is_inferred="true"} ! positive regulation of plasma membrane bounded cell projection assembly
 is_a: GO:1904170 {is_inferred="true"} ! regulation of bleb assembly
 
 [Term]
@@ -89969,17 +89979,16 @@
 
 [Term]
 id: GO:1905924 ! regulation of invadopodium assembly
-is_a: GO:0060491 {is_inferred="true"} ! regulation of cell projection assembly
+is_a: GO:0120032 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:1905925 ! negative regulation of invadopodium assembly
-is_a: GO:0031345 {is_inferred="true"} ! negative regulation of cell projection organization
+is_a: GO:0120033 {is_inferred="true"} ! negative regulation of plasma membrane bounded cell projection assembly
 is_a: GO:1905924 {is_inferred="true"} ! regulation of invadopodium assembly
 
 [Term]
 id: GO:1905926 ! positive regulation of invadopodium assembly
-is_a: GO:0031346 {is_inferred="true"} ! positive regulation of cell projection organization
-is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
+is_a: GO:0120034 {is_inferred="true"} ! positive regulation of plasma membrane bounded cell projection assembly
 is_a: GO:1905924 {is_inferred="true"} ! regulation of invadopodium assembly
 
 [Term]
@@ -93851,17 +93860,16 @@
 
 [Term]
 id: GO:2000547 ! regulation of dendritic cell dendrite assembly
-is_a: GO:0060491 {is_inferred="true"} ! regulation of cell projection assembly
+is_a: GO:0120032 {is_inferred="true"} ! regulation of plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:2000548 ! negative regulation of dendritic cell dendrite assembly
-is_a: GO:0031345 {is_inferred="true"} ! negative regulation of cell projection organization
+is_a: GO:0120033 {is_inferred="true"} ! negative regulation of plasma membrane bounded cell projection assembly
 is_a: GO:2000547 {is_inferred="true"} ! regulation of dendritic cell dendrite assembly
 
 [Term]
 id: GO:2000549 ! positive regulation of dendritic cell dendrite assembly
-is_a: GO:0031346 {is_inferred="true"} ! positive regulation of cell projection organization
-is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
+is_a: GO:0120034 {is_inferred="true"} ! positive regulation of plasma membrane bounded cell projection assembly
 is_a: GO:2000547 {is_inferred="true"} ! regulation of dendritic cell dendrite assembly
 
 [Term]
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40806)
+++ go_inferences.obo	(working copy)
@@ -8191,11 +8191,6 @@
 is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
 
 [Term]
-id: GO:0007288 ! sperm axoneme assembly
-is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
-
-[Term]
 id: GO:0007289 ! spermatid nucleus differentiation
 is_a: GO:0022414 {is_inferred="true"} ! reproductive process
 
@@ -19821,11 +19816,11 @@
 
 [Term]
 id: GO:0030032 ! lamellipodium assembly
-is_a: GO:0030031 {is_inferred="true"} ! cell projection assembly
+is_a: GO:0120031 {is_inferred="true"} ! plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:0030033 ! microvillus assembly
-is_a: GO:0030031 {is_inferred="true"} ! cell projection assembly
+is_a: GO:0120031 {is_inferred="true"} ! plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:0030034 ! microvillar actin bundle assembly
@@ -19833,7 +19828,7 @@
 
 [Term]
 id: GO:0030035 ! microspike assembly
-is_a: GO:0030031 {is_inferred="true"} ! cell projection assembly
+is_a: GO:0120031 {is_inferred="true"} ! plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:0030036 ! actin cytoskeleton organization
@@ -21577,7 +21572,7 @@
 
 [Term]
 id: GO:0031269 ! pseudopodium assembly
-is_a: GO:0030031 {is_inferred="true"} ! cell projection assembly
+is_a: GO:0120031 {is_inferred="true"} ! plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:0031272 ! regulation of pseudopodium assembly
@@ -21836,8 +21831,8 @@
 id: GO:0031382 ! mating projection assembly
 is_a: GO:0003006 {is_inferred="true"} ! developmental process involved in reproduction
 is_a: GO:0010927 {is_inferred="true"} ! cellular component assembly involved in morphogenesis
-is_a: GO:0030031 {is_inferred="true"} ! cell projection assembly
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0120031 {is_inferred="true"} ! plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:0031383 ! regulation of mating projection assembly
@@ -22758,7 +22753,7 @@
 
 [Term]
 id: GO:0032060 ! bleb assembly
-is_a: GO:0030031 {is_inferred="true"} ! cell projection assembly
+is_a: GO:0120031 {is_inferred="true"} ! plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:0032065 ! cortical protein anchoring
@@ -23867,6 +23862,10 @@
 is_a: GO:0045185 {is_inferred="true"} ! maintenance of protein location
 
 [Term]
+id: GO:0032510 ! endosome to lysosome transport via multivesicular body sorting pathway
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
+
+[Term]
 id: GO:0032515 ! negative regulation of phosphoprotein phosphatase activity
 is_a: GO:0010923 {is_inferred="true"} ! negative regulation of phosphatase activity
 is_a: GO:0035308 {is_inferred="true"} ! negative regulation of protein dephosphorylation
@@ -28030,6 +28029,10 @@
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 
 [Term]
+id: GO:0034460 ! uropod assembly
+is_a: GO:0120031 {is_inferred="true"} ! plasma membrane bounded cell projection assembly
+
+[Term]
 id: GO:0034462 ! small-subunit processome assembly
 is_a: GO:0022618 {is_inferred="true"} ! ribonucleoprotein complex assembly
 
@@ -28582,7 +28585,7 @@
 
 [Term]
 id: GO:0035082 ! axoneme assembly
-is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
+is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
 
 [Term]
 id: GO:0035091 ! phosphatidylinositol binding
@@ -28688,7 +28691,7 @@
 [Term]
 id: GO:0035231 ! cytoneme assembly
 is_a: GO:0010927 {is_inferred="true"} ! cellular component assembly involved in morphogenesis
-is_a: GO:0030031 {is_inferred="true"} ! cell projection assembly
+is_a: GO:0120031 {is_inferred="true"} ! plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:0035232 ! germ cell attraction
@@ -33370,6 +33373,7 @@
 [Term]
 id: GO:0043328 ! protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
 is_a: GO:0006623 {is_inferred="true"} ! protein targeting to vacuole
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:0043329 ! protein targeting to membrane involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
@@ -40588,7 +40592,7 @@
 
 [Term]
 id: GO:0046847 ! filopodium assembly
-is_a: GO:0030031 {is_inferred="true"} ! cell projection assembly
+is_a: GO:0120031 {is_inferred="true"} ! plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:0046848 ! hydroxyapatite binding
@@ -46220,9 +46224,9 @@
 
 [Term]
 id: GO:0060271 ! cilium assembly
-is_a: GO:0030031 {is_inferred="true"} ! cell projection assembly
 is_a: GO:0044782 {is_inferred="true"} ! cilium organization
 is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
+is_a: GO:0120031 {is_inferred="true"} ! plasma membrane bounded cell projection assembly
 
 [Term]
 id: GO:0060278 ! regulation of ovulation
@@ -57647,6 +57651,10 @@
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
 [Term]
+id: GO:0097026 ! dendritic cell dendrite assembly
+is_a: GO:0120031 {is_inferred="true"} ! plasma membrane bounded cell projection assembly
+
+[Term]
 id: GO:0097029 ! mature conventional dendritic cell differentiation
 is_a: GO:0002573 {is_inferred="true"} ! myeloid leukocyte differentiation
 
@@ -57834,6 +57842,10 @@
 is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
 
 [Term]
+id: GO:0097178 ! ruffle assembly
+is_a: GO:0120031 {is_inferred="true"} ! plasma membrane bounded cell projection assembly
+
+[Term]
 id: GO:0097184 ! response to azide
 is_a: GO:0010035 {is_inferred="true"} ! response to inorganic substance
 is_a: GO:1901698 {is_inferred="true"} ! response to nitrogen compound
@@ -61031,6 +61043,10 @@
 is_a: GO:1902600 {is_inferred="true"} ! hydrogen ion transmembrane transport
 
 [Term]
+id: GO:0120031 ! plasma membrane bounded cell projection assembly
+is_a: GO:0030031 {is_inferred="true"} ! cell projection assembly
+
+[Term]
 id: GO:0140009 ! L-aspartate import across plasma membrane
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 is_a: GO:0089712 {is_inferred="true"} ! L-aspartate transmembrane transport
@@ -89707,7 +89723,7 @@
 
 [Term]
 id: GO:1905877 ! invadopodium assembly
-is_a: GO:0030031 {is_inferred="true"} ! cell projection assembly
+is_a: GO:0120031 {is_inferred="true"} ! plasma membrane bounded cell projection assembly
 is_a: GO:1905863 {is_inferred="true"} ! invadopodium organization
 
 [Term]
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40803)
+++ go_inferences.obo	(working copy)
@@ -20325,8 +20325,8 @@
 
 [Term]
 id: GO:0030474 ! spindle pole body duplication
+is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
 is_a: GO:0051300 {is_inferred="true"} ! spindle pole body organization
-is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
 
 [Term]
 id: GO:0030476 ! ascospore wall assembly
@@ -21223,16 +21223,17 @@
 
 [Term]
 id: GO:0031023 ! microtubule organizing center organization
-is_a: GO:0006996 {is_inferred="true"} ! organelle organization
+is_a: GO:0016043 {is_inferred="true"} ! cellular component organization
 
 [Term]
 id: GO:0031024 ! interphase microtubule organizing center assembly
-is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
+is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
 
 [Term]
 id: GO:0031025 ! equatorial microtubule organizing center disassembly
+is_a: GO:0022411 {is_inferred="true"} ! cellular component disassembly
 is_a: GO:0031023 {is_inferred="true"} ! microtubule organizing center organization
-is_a: GO:1903008 {is_inferred="true"} ! organelle disassembly
+is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
 [Term]
 id: GO:0031026 ! glutamate synthase complex
@@ -44542,6 +44543,7 @@
 
 [Term]
 id: GO:0051642 ! centrosome localization
+is_a: GO:0051640 {is_inferred="true"} ! organelle localization
 is_a: GO:0061842 {is_inferred="true"} ! microtubule organizing center localization
 
 [Term]
@@ -49162,7 +49164,7 @@
 
 [Term]
 id: GO:0061842 ! microtubule organizing center localization
-is_a: GO:0051640 {is_inferred="true"} ! organelle localization
+is_a: GO:0051179 {is_inferred="true"} ! localization
 
 [Term]
 id: GO:0061845 ! neuron projection branch point
@@ -50462,7 +50464,6 @@
 
 [Term]
 id: GO:0070632 ! establishment of spindle pole body localization
-is_a: GO:0051656 {is_inferred="true"} ! establishment of organelle localization
 is_a: GO:0070631 {is_inferred="true"} ! spindle pole body localization
 
 [Term]
@@ -81522,8 +81523,8 @@
 
 [Term]
 id: GO:1904185 ! equatorial microtubule organizing center assembly
+is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
 is_a: GO:0031023 {is_inferred="true"} ! microtubule organizing center organization
-is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
 
 [Term]
 id: GO:1904186 ! post-anaphase microtubule array organization
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40796)
+++ go_inferences.obo	(working copy)
@@ -57608,14 +57608,6 @@
 is_a: GO:0030154 {is_inferred="true"} ! cell differentiation
 
 [Term]
-id: GO:0090688 ! cleavage furrow rim
-is_a: GO:0032155 {is_inferred="true"} ! cell division site part
-
-[Term]
-id: GO:0090689 ! cleavage furrow leading edge
-is_a: GO:0032155 {is_inferred="true"} ! cell division site part
-
-[Term]
 id: GO:0090696 ! post-embryonic plant organ development
 is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40694)
+++ go_inferences.obo	(working copy)
@@ -22204,6 +22204,15 @@
 is_a: GO:0044463 {is_inferred="true"} ! cell projection part
 
 [Term]
+id: GO:0031567 ! mitotic cell size control checkpoint
+is_a: GO:0007093 {is_inferred="true"} ! mitotic cell cycle checkpoint
+
+[Term]
+id: GO:0031568 ! G1 cell size control checkpoint
+is_a: GO:0031567 {is_inferred="true"} ! mitotic cell size control checkpoint
+is_a: GO:2000134 {is_inferred="true"} ! negative regulation of G1/S transition of mitotic cell cycle
+
+[Term]
 id: GO:0031569 ! G2 cell size control checkpoint
 is_a: GO:0010972 {is_inferred="true"} ! negative regulation of G2/M transition of mitotic cell cycle
 is_a: GO:0031567 {is_inferred="true"} ! mitotic cell size control checkpoint
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40679)
+++ go_inferences.obo	(working copy)
@@ -22752,7 +22752,7 @@
 
 [Term]
 id: GO:0032065 ! cortical protein anchoring
-is_a: GO:0051220 {is_inferred="true"} ! cytoplasmic sequestering of protein
+is_a: GO:0032507 {is_inferred="true"} ! maintenance of protein location in cell
 
 [Term]
 id: GO:0032066 ! nucleolus to nucleoplasm transport
@@ -29063,10 +29063,6 @@
 is_a: GO:0098661 {is_inferred="true"} ! inorganic anion transmembrane transport
 
 [Term]
-id: GO:0035437 ! maintenance of protein localization in endoplasmic reticulum
-is_a: GO:0051220 {is_inferred="true"} ! cytoplasmic sequestering of protein
-
-[Term]
 id: GO:0035438 ! cyclic-di-GMP binding
 is_a: GO:0030551 {is_inferred="true"} ! cyclic nucleotide binding
 is_a: GO:0032561 {is_inferred="true"} ! guanyl ribonucleotide binding
@@ -43480,10 +43476,6 @@
 is_a: GO:0046914 {is_inferred="true"} ! transition metal ion binding
 
 [Term]
-id: GO:0051220 ! cytoplasmic sequestering of protein
-is_a: GO:0032507 {is_inferred="true"} ! maintenance of protein location in cell
-
-[Term]
 id: GO:0051223 ! regulation of protein transport
 is_a: GO:0090087 {is_inferred="true"} ! regulation of peptide transport
 
@@ -54406,10 +54398,6 @@
 is_a: GO:0072598 {is_inferred="true"} ! protein localization to chloroplast
 
 [Term]
-id: GO:0072597 ! maintenance of protein location in chloroplast
-is_a: GO:0051220 {is_inferred="true"} ! cytoplasmic sequestering of protein
-
-[Term]
 id: GO:0072598 ! protein localization to chloroplast
 is_a: GO:0033365 {is_inferred="true"} ! protein localization to organelle
 
@@ -54426,10 +54414,6 @@
 is_a: GO:0070585 {is_inferred="true"} ! protein localization to mitochondrion
 
 [Term]
-id: GO:0072656 ! maintenance of protein location in mitochondrion
-is_a: GO:0051220 {is_inferred="true"} ! cytoplasmic sequestering of protein
-
-[Term]
 id: GO:0072659 ! protein localization to plasma membrane
 is_a: GO:0072657 {is_inferred="true"} ! protein localization to membrane
 is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
@@ -54448,10 +54432,6 @@
 is_a: GO:0072662 {is_inferred="true"} ! protein localization to peroxisome
 
 [Term]
-id: GO:0072664 ! maintenance of protein location in peroxisome
-is_a: GO:0051220 {is_inferred="true"} ! cytoplasmic sequestering of protein
-
-[Term]
 id: GO:0072665 ! protein localization to vacuole
 is_a: GO:0033365 {is_inferred="true"} ! protein localization to organelle
 
@@ -54460,10 +54440,6 @@
 is_a: GO:0072665 {is_inferred="true"} ! protein localization to vacuole
 
 [Term]
-id: GO:0072667 ! maintenance of protein location in vacuole
-is_a: GO:0051220 {is_inferred="true"} ! cytoplasmic sequestering of protein
-
-[Term]
 id: GO:0072672 ! neutrophil extravasation
 is_a: GO:1990266 {is_inferred="true"} ! neutrophil migration
 
@@ -87877,7 +87853,6 @@
 [Term]
 id: GO:1905481 ! cytoplasmic sequestering of protein involved in mitotic DNA replication checkpoint
 is_a: GO:0051220 {is_inferred="true"} ! cytoplasmic sequestering of protein
-is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
 id: GO:1905482 ! cytoplasmic sequestering of protein involved in G2 DNA damage checkpoint
@@ -87988,7 +87963,6 @@
 
 [Term]
 id: GO:1905507 ! cytoplasmic sequestering of protein involved in mitotic G2 DNA damage checkpoint
-is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 is_a: GO:1905482 {is_inferred="true"} ! cytoplasmic sequestering of protein involved in G2 DNA damage checkpoint
 
 [Term]
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40522)
+++ go_inferences.obo	(working copy)
@@ -81896,6 +81896,7 @@
 id: GO:1904259 ! regulation of basement membrane assembly involved in embryonic body morphogenesis
 is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
 is_a: GO:0045995 {is_inferred="true"} ! regulation of embryonic development
+is_a: GO:0110011 {is_inferred="true"} ! regulation of basement membrane organization
 is_a: GO:1901201 {is_inferred="true"} ! regulation of extracellular matrix assembly
 
 [Term]
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40517)
+++ go_inferences.obo	(working copy)
@@ -11853,24 +11853,12 @@
 is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
 
 [Term]
-id: GO:0010532 ! regulation of activation of JAK1 kinase activity
-is_a: GO:0010533 {is_inferred="true"} ! regulation of activation of Janus kinase activity
-
-[Term]
 id: GO:0010533 ! regulation of activation of Janus kinase activity
 is_a: GO:0045859 {is_inferred="true"} ! regulation of protein kinase activity
+is_a: GO:0046425 {is_inferred="true"} ! regulation of JAK-STAT cascade
 is_a: GO:0050730 {is_inferred="true"} ! regulation of peptidyl-tyrosine phosphorylation
 
 [Term]
-id: GO:0010534 ! regulation of activation of JAK2 kinase activity
-is_a: GO:0010533 {is_inferred="true"} ! regulation of activation of Janus kinase activity
-
-[Term]
-id: GO:0010535 ! positive regulation of activation of JAK2 kinase activity
-is_a: GO:0010534 {is_inferred="true"} ! regulation of activation of JAK2 kinase activity
-is_a: GO:0010536 {is_inferred="true"} ! positive regulation of activation of Janus kinase activity
-
-[Term]
 id: GO:0010536 ! positive regulation of activation of Janus kinase activity
 is_a: GO:0010533 {is_inferred="true"} ! regulation of activation of Janus kinase activity
 is_a: GO:0045860 {is_inferred="true"} ! positive regulation of protein kinase activity
@@ -11878,11 +11866,6 @@
 is_a: GO:0050731 {is_inferred="true"} ! positive regulation of peptidyl-tyrosine phosphorylation
 
 [Term]
-id: GO:0010537 ! positive regulation of activation of JAK1 kinase activity
-is_a: GO:0010532 {is_inferred="true"} ! regulation of activation of JAK1 kinase activity
-is_a: GO:0010536 {is_inferred="true"} ! positive regulation of activation of Janus kinase activity
-
-[Term]
 id: GO:0010542 ! nitrate efflux transmembrane transporter activity
 is_a: GO:0015112 {is_inferred="true"} ! nitrate transmembrane transporter activity
 is_a: GO:0015562 {is_inferred="true"} ! efflux transmembrane transporter activity
@@ -31747,111 +31730,15 @@
 is_a: GO:0050730 {is_inferred="true"} ! regulation of peptidyl-tyrosine phosphorylation
 
 [Term]
-id: GO:0042510 ! regulation of tyrosine phosphorylation of Stat1 protein
-is_a: GO:0042509 {is_inferred="true"} ! regulation of tyrosine phosphorylation of STAT protein
-
-[Term]
-id: GO:0042511 ! positive regulation of tyrosine phosphorylation of Stat1 protein
-is_a: GO:0042510 {is_inferred="true"} ! regulation of tyrosine phosphorylation of Stat1 protein
-is_a: GO:0042531 {is_inferred="true"} ! positive regulation of tyrosine phosphorylation of STAT protein
-
-[Term]
-id: GO:0042512 ! negative regulation of tyrosine phosphorylation of Stat1 protein
-is_a: GO:0042510 {is_inferred="true"} ! regulation of tyrosine phosphorylation of Stat1 protein
-is_a: GO:0042532 {is_inferred="true"} ! negative regulation of tyrosine phosphorylation of STAT protein
-
-[Term]
-id: GO:0042513 ! regulation of tyrosine phosphorylation of Stat2 protein
-is_a: GO:0042509 {is_inferred="true"} ! regulation of tyrosine phosphorylation of STAT protein
-
-[Term]
-id: GO:0042514 ! negative regulation of tyrosine phosphorylation of Stat2 protein
-is_a: GO:0042513 {is_inferred="true"} ! regulation of tyrosine phosphorylation of Stat2 protein
-is_a: GO:0042532 {is_inferred="true"} ! negative regulation of tyrosine phosphorylation of STAT protein
-
-[Term]
-id: GO:0042515 ! positive regulation of tyrosine phosphorylation of Stat2 protein
-is_a: GO:0042513 {is_inferred="true"} ! regulation of tyrosine phosphorylation of Stat2 protein
-is_a: GO:0042531 {is_inferred="true"} ! positive regulation of tyrosine phosphorylation of STAT protein
-
-[Term]
-id: GO:0042516 ! regulation of tyrosine phosphorylation of Stat3 protein
-is_a: GO:0042509 {is_inferred="true"} ! regulation of tyrosine phosphorylation of STAT protein
-
-[Term]
-id: GO:0042517 ! positive regulation of tyrosine phosphorylation of Stat3 protein
-is_a: GO:0042516 {is_inferred="true"} ! regulation of tyrosine phosphorylation of Stat3 protein
-is_a: GO:0042531 {is_inferred="true"} ! positive regulation of tyrosine phosphorylation of STAT protein
-
-[Term]
-id: GO:0042518 ! negative regulation of tyrosine phosphorylation of Stat3 protein
-is_a: GO:0042516 {is_inferred="true"} ! regulation of tyrosine phosphorylation of Stat3 protein
-is_a: GO:0042532 {is_inferred="true"} ! negative regulation of tyrosine phosphorylation of STAT protein
-
-[Term]
-id: GO:0042519 ! regulation of tyrosine phosphorylation of Stat4 protein
-is_a: GO:0042509 {is_inferred="true"} ! regulation of tyrosine phosphorylation of STAT protein
-
-[Term]
-id: GO:0042520 ! positive regulation of tyrosine phosphorylation of Stat4 protein
-is_a: GO:0042519 {is_inferred="true"} ! regulation of tyrosine phosphorylation of Stat4 protein
-is_a: GO:0042531 {is_inferred="true"} ! positive regulation of tyrosine phosphorylation of STAT protein
-
-[Term]
-id: GO:0042521 ! negative regulation of tyrosine phosphorylation of Stat4 protein
-is_a: GO:0042519 {is_inferred="true"} ! regulation of tyrosine phosphorylation of Stat4 protein
-is_a: GO:0042532 {is_inferred="true"} ! negative regulation of tyrosine phosphorylation of STAT protein
-
-[Term]
-id: GO:0042522 ! regulation of tyrosine phosphorylation of Stat5 protein
-is_a: GO:0042509 {is_inferred="true"} ! regulation of tyrosine phosphorylation of STAT protein
-
-[Term]
-id: GO:0042523 ! positive regulation of tyrosine phosphorylation of Stat5 protein
-is_a: GO:0042522 {is_inferred="true"} ! regulation of tyrosine phosphorylation of Stat5 protein
-is_a: GO:0042531 {is_inferred="true"} ! positive regulation of tyrosine phosphorylation of STAT protein
-
-[Term]
-id: GO:0042524 ! negative regulation of tyrosine phosphorylation of Stat5 protein
-is_a: GO:0042522 {is_inferred="true"} ! regulation of tyrosine phosphorylation of Stat5 protein
-is_a: GO:0042532 {is_inferred="true"} ! negative regulation of tyrosine phosphorylation of STAT protein
-
-[Term]
-id: GO:0042525 ! regulation of tyrosine phosphorylation of Stat6 protein
-is_a: GO:0042509 {is_inferred="true"} ! regulation of tyrosine phosphorylation of STAT protein
-
-[Term]
-id: GO:0042526 ! positive regulation of tyrosine phosphorylation of Stat6 protein
-is_a: GO:0042525 {is_inferred="true"} ! regulation of tyrosine phosphorylation of Stat6 protein
-is_a: GO:0042531 {is_inferred="true"} ! positive regulation of tyrosine phosphorylation of STAT protein
-
-[Term]
-id: GO:0042527 ! negative regulation of tyrosine phosphorylation of Stat6 protein
-is_a: GO:0042525 {is_inferred="true"} ! regulation of tyrosine phosphorylation of Stat6 protein
-is_a: GO:0042532 {is_inferred="true"} ! negative regulation of tyrosine phosphorylation of STAT protein
-
-[Term]
-id: GO:0042528 ! regulation of tyrosine phosphorylation of Stat7 protein
-is_a: GO:0042509 {is_inferred="true"} ! regulation of tyrosine phosphorylation of STAT protein
-
-[Term]
-id: GO:0042529 ! positive regulation of tyrosine phosphorylation of Stat7 protein
-is_a: GO:0042528 {is_inferred="true"} ! regulation of tyrosine phosphorylation of Stat7 protein
-is_a: GO:0042531 {is_inferred="true"} ! positive regulation of tyrosine phosphorylation of STAT protein
-
-[Term]
-id: GO:0042530 ! negative regulation of tyrosine phosphorylation of Stat7 protein
-is_a: GO:0042528 {is_inferred="true"} ! regulation of tyrosine phosphorylation of Stat7 protein
-is_a: GO:0042532 {is_inferred="true"} ! negative regulation of tyrosine phosphorylation of STAT protein
-
-[Term]
 id: GO:0042531 ! positive regulation of tyrosine phosphorylation of STAT protein
 is_a: GO:0042509 {is_inferred="true"} ! regulation of tyrosine phosphorylation of STAT protein
+is_a: GO:0046427 {is_inferred="true"} ! positive regulation of JAK-STAT cascade
 is_a: GO:0050731 {is_inferred="true"} ! positive regulation of peptidyl-tyrosine phosphorylation
 
 [Term]
 id: GO:0042532 ! negative regulation of tyrosine phosphorylation of STAT protein
 is_a: GO:0042509 {is_inferred="true"} ! regulation of tyrosine phosphorylation of STAT protein
+is_a: GO:0046426 {is_inferred="true"} ! negative regulation of JAK-STAT cascade
 is_a: GO:0050732 {is_inferred="true"} ! negative regulation of peptidyl-tyrosine phosphorylation
 
 [Term]
@@ -74143,8 +74030,8 @@
 is_a: GO:1902566 {is_inferred="true"} ! regulation of eosinophil activation
 
 [Term]
-id: GO:1902569 ! negative regulation of activation of JAK2 kinase activity
-is_a: GO:0010534 {is_inferred="true"} ! regulation of activation of JAK2 kinase activity
+id: GO:1902569 ! negative regulation of activation of Janus kinase activity
+is_a: GO:0010533 {is_inferred="true"} ! regulation of activation of Janus kinase activity
 is_a: GO:0050732 {is_inferred="true"} ! negative regulation of peptidyl-tyrosine phosphorylation
 
 [Term]
@@ -77284,20 +77171,6 @@
 is_a: GO:0008104 {is_inferred="true"} ! protein localization
 
 [Term]
-id: GO:1903261 ! regulation of serine phosphorylation of STAT3 protein
-is_a: GO:0033139 {is_inferred="true"} ! regulation of peptidyl-serine phosphorylation of STAT protein
-
-[Term]
-id: GO:1903262 ! negative regulation of serine phosphorylation of STAT3 protein
-is_a: GO:0033140 {is_inferred="true"} ! negative regulation of peptidyl-serine phosphorylation of STAT protein
-is_a: GO:1903261 {is_inferred="true"} ! regulation of serine phosphorylation of STAT3 protein
-
-[Term]
-id: GO:1903263 ! positive regulation of serine phosphorylation of STAT3 protein
-is_a: GO:0033141 {is_inferred="true"} ! positive regulation of peptidyl-serine phosphorylation of STAT protein
-is_a: GO:1903261 {is_inferred="true"} ! regulation of serine phosphorylation of STAT3 protein
-
-[Term]
 id: GO:1903264 ! nitrate reductase activity involved in anaerobic electron transport chain
 is_a: GO:0008940 {is_inferred="true"} ! nitrate reductase activity
 
@@ -93142,11 +93015,13 @@
 [Term]
 id: GO:2000365 ! negative regulation of STAT protein import into nucleus
 is_a: GO:0042308 {is_inferred="true"} ! negative regulation of protein import into nucleus
+is_a: GO:0046426 {is_inferred="true"} ! negative regulation of JAK-STAT cascade
 is_a: GO:2000364 {is_inferred="true"} ! regulation of STAT protein import into nucleus
 
 [Term]
 id: GO:2000366 ! positive regulation of STAT protein import into nucleus
 is_a: GO:0042307 {is_inferred="true"} ! positive regulation of protein import into nucleus
+is_a: GO:0046427 {is_inferred="true"} ! positive regulation of JAK-STAT cascade
 is_a: GO:2000364 {is_inferred="true"} ! regulation of STAT protein import into nucleus
 
 [Term]
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40491)
+++ go_inferences.obo	(working copy)
@@ -7666,9 +7666,9 @@
 is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
 
 [Term]
-id: GO:0006851 ! mitochondrial calcium ion transport
-is_a: GO:0006816 {is_inferred="true"} ! calcium ion transport
-is_a: GO:0006839 {is_inferred="true"} ! mitochondrial transport
+id: GO:0006851 ! mitochondrial calcium ion transmembrane transport
+is_a: GO:0070588 {is_inferred="true"} ! calcium ion transmembrane transport
+is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:0006853 ! carnitine shuttle
@@ -15630,6 +15630,7 @@
 
 [Term]
 id: GO:0015860 ! purine nucleoside transmembrane transport
+is_a: GO:0072530 {is_inferred="true"} ! purine-containing compound transmembrane transport
 is_a: GO:1901642 {is_inferred="true"} ! nucleoside transmembrane transport
 
 [Term]
@@ -30373,11 +30374,9 @@
 
 [Term]
 id: GO:0036444 ! mitochondrial calcium uptake
-is_a: GO:0006851 {is_inferred="true"} ! mitochondrial calcium ion transport
+is_a: GO:0006851 {is_inferred="true"} ! mitochondrial calcium ion transmembrane transport
 is_a: GO:0060401 {is_inferred="true"} ! cytosolic calcium ion transport
 is_a: GO:0070509 {is_inferred="true"} ! calcium ion import
-is_a: GO:0070588 {is_inferred="true"} ! calcium ion transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:0036502 ! Derlin-1-VIMP complex
@@ -60156,10 +60155,9 @@
 
 [Term]
 id: GO:0099093 ! mitochondrial calcium release
-is_a: GO:0006851 {is_inferred="true"} ! mitochondrial calcium ion transport
+is_a: GO:0006851 {is_inferred="true"} ! mitochondrial calcium ion transmembrane transport
 is_a: GO:0051209 {is_inferred="true"} ! release of sequestered calcium ion into cytosol
 is_a: GO:1901660 {is_inferred="true"} ! calcium ion export
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:0099094 ! ligand-gated cation channel activity
@@ -61193,6 +61191,14 @@
 is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
 
 [Term]
+id: GO:0140021 ! mitochondrial ADP transmembrane transport
+is_a: GO:0015866 {is_inferred="true"} ! ADP transport
+is_a: GO:0072530 {is_inferred="true"} ! purine-containing compound transmembrane transport
+is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:1901679 {is_inferred="true"} ! nucleotide transmembrane transport
+is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
+
+[Term]
 id: GO:1900000 ! regulation of anthocyanin catabolic process
 is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
 is_a: GO:0031537 {is_inferred="true"} ! regulation of anthocyanin metabolic process
@@ -73203,6 +73209,8 @@
 
 [Term]
 id: GO:1902361 ! mitochondrial pyruvate transmembrane transport
+is_a: GO:0006850 {is_inferred="true"} ! mitochondrial pyruvate transport
+is_a: GO:1901475 {is_inferred="true"} ! pyruvate transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
@@ -90874,6 +90882,7 @@
 
 [Term]
 id: GO:1990540 ! mitochondrial manganese ion transmembrane transport
+is_a: GO:0071421 {is_inferred="true"} ! manganese ion transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
@@ -90882,11 +90891,17 @@
 is_a: GO:1990546 {is_inferred="true"} ! mitochondrial tricarboxylic acid transmembrane transport
 
 [Term]
+id: GO:1990542 ! mitochondrial transmembrane transport
+is_a: GO:0006839 {is_inferred="true"} ! mitochondrial transport
+is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
+
+[Term]
 id: GO:1990543 ! mitochondrial S-adenosyl-L-methionine transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990544 ! mitochondrial ATP transmembrane transport
+is_a: GO:0015867 {is_inferred="true"} ! ATP transport
 is_a: GO:0072530 {is_inferred="true"} ! purine-containing compound transmembrane transport
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 is_a: GO:1901679 {is_inferred="true"} ! nucleotide transmembrane transport
@@ -90894,6 +90909,7 @@
 
 [Term]
 id: GO:1990545 ! mitochondrial thiamine pyrophosphate transmembrane transport
+is_a: GO:0030974 {is_inferred="true"} ! thiamine pyrophosphate transport
 is_a: GO:0072531 {is_inferred="true"} ! pyrimidine-containing compound transmembrane transport
 is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
@@ -90906,14 +90922,17 @@
 
 [Term]
 id: GO:1990547 ! mitochondrial phosphate ion transmembrane transport
+is_a: GO:0035435 {is_inferred="true"} ! phosphate ion transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990548 ! mitochondrial FAD transmembrane transport
+is_a: GO:0035350 {is_inferred="true"} ! FAD transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990549 ! mitochondrial NAD transmembrane transport
+is_a: GO:0035352 {is_inferred="true"} ! NAD transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
@@ -90924,15 +90943,18 @@
 
 [Term]
 id: GO:1990551 ! mitochondrial 2-oxoadipate transmembrane transport
+is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
 is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990553 ! mitochondrial 5'-adenylyl sulfate transmembrane transport
+is_a: GO:1902558 {is_inferred="true"} ! 5'-adenylyl sulfate transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990554 ! mitochondrial 3'-phospho-5'-adenylyl sulfate transmembrane transport
+is_a: GO:1902559 {is_inferred="true"} ! 3'-phospho-5'-adenylyl sulfate transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
@@ -90980,6 +91002,8 @@
 
 [Term]
 id: GO:1990575 ! mitochondrial L-ornithine transmembrane transport
+is_a: GO:0000066 {is_inferred="true"} ! mitochondrial ornithine transport
+is_a: GO:1903352 {is_inferred="true"} ! L-ornithine transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
@@ -91029,8 +91053,14 @@
 [Term]
 id: GO:1990614 ! mitochondrial magnesium ion transmembrane transport
 is_a: GO:0045016 {is_inferred="true"} ! mitochondrial magnesium ion transport
+is_a: GO:1903830 {is_inferred="true"} ! magnesium ion transmembrane transport
+is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
+id: GO:1990616 ! magnesium ion export from mitochondrion
+is_a: GO:1990614 {is_inferred="true"} ! mitochondrial magnesium ion transmembrane transport
+
+[Term]
 id: GO:1990621 ! ESCRT IV complex
 is_a: GO:0044440 {is_inferred="true"} ! endosomal part
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40343)
+++ go_inferences.obo	(working copy)
@@ -572,6 +572,10 @@
 is_a: GO:0007049 {is_inferred="true"} ! cell cycle
 
 [Term]
+id: GO:0000280 ! nuclear division
+is_a: GO:0048285 {is_inferred="true"} ! organelle fission
+
+[Term]
 id: GO:0000281 ! mitotic cytokinesis
 is_a: GO:0061640 {is_inferred="true"} ! cytoskeleton-dependent cytokinesis
 is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
@@ -10860,6 +10864,10 @@
 is_a: GO:1905392 {is_inferred="true"} ! plant organ morphogenesis
 
 [Term]
+id: GO:0010020 ! chloroplast fission
+is_a: GO:0043572 {is_inferred="true"} ! plastid fission
+
+[Term]
 id: GO:0010021 ! amylopectin biosynthetic process
 is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 is_a: GO:1901137 {is_inferred="true"} ! carbohydrate derivative biosynthetic process
@@ -16672,6 +16680,10 @@
 is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
 [Term]
+id: GO:0016559 ! peroxisome fission
+is_a: GO:0048285 {is_inferred="true"} ! organelle fission
+
+[Term]
 id: GO:0016562 ! protein import into peroxisome matrix, receptor recycling
 is_a: GO:0001881 {is_inferred="true"} ! receptor recycling
 
@@ -34014,6 +34026,14 @@
 is_a: GO:0043567 {is_inferred="true"} ! regulation of insulin-like growth factor receptor signaling pathway
 
 [Term]
+id: GO:0043572 ! plastid fission
+is_a: GO:0048285 {is_inferred="true"} ! organelle fission
+
+[Term]
+id: GO:0043573 ! leucoplast fission
+is_a: GO:0043572 {is_inferred="true"} ! plastid fission
+
+[Term]
 id: GO:0043574 ! peroxisomal transport
 is_a: GO:0006810 {is_inferred="true"} ! transport
 
@@ -58210,6 +58230,10 @@
 is_a: GO:0044445 {is_inferred="true"} ! cytosolic part
 
 [Term]
+id: GO:0097352 ! autophagosome maturation
+is_a: GO:0097576 {is_inferred="true"} ! vacuole fusion
+
+[Term]
 id: GO:0097355 ! protein localization to heterochromatin
 is_a: GO:0071168 {is_inferred="true"} ! protein localization to chromatin
 
@@ -58311,6 +58335,10 @@
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
 [Term]
+id: GO:0097576 ! vacuole fusion
+is_a: GO:0048284 {is_inferred="true"} ! organelle fusion
+
+[Term]
 id: GO:0097578 ! sequestering of copper ion
 is_a: GO:1902578 {is_inferred="true"} ! single-organism localization
 
@@ -61150,7 +61178,13 @@
 is_a: GO:0015556 {is_inferred="true"} ! C4-dicarboxylate transmembrane transporter activity
 
 [Term]
+id: GO:0140013 ! meiotic nuclear division
+is_a: GO:0000280 {is_inferred="true"} ! nuclear division
+is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
+
+[Term]
 id: GO:0140014 ! mitotic nuclear division
+is_a: GO:0000280 {is_inferred="true"} ! nuclear division
 is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
------------------------------------------------------------------------
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changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40271)
+++ go_inferences.obo	(working copy)
@@ -49306,6 +49306,11 @@
 is_a: GO:1905960 {is_inferred="true"} ! response to differentiation-inducing factor 2
 
 [Term]
+id: GO:0061866 ! negative regulation of histone H3-S10 phosphorylation
+is_a: GO:0033128 {is_inferred="true"} ! negative regulation of histone phosphorylation
+is_a: GO:0033137 {is_inferred="true"} ! negative regulation of peptidyl-serine phosphorylation
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40270)
+++ go_inferences.obo	(working copy)
@@ -59308,6 +59308,10 @@
 is_a: GO:0098859 {is_inferred="true"} ! actin filament bundle of actin-based cell projection
 
 [Term]
+id: GO:0098863 ! nuclear migration by microtubule mediated pushing forces
+is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
+
+[Term]
 id: GO:0098866 ! multivesicular body fusion to apical plasma membrane
 is_a: GO:0090174 {is_inferred="true"} ! organelle membrane fusion
 
------------------------------------------------------------------------
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changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40269)
+++ go_inferences.obo	(working copy)
@@ -49301,6 +49301,11 @@
 is_a: GO:0070588 {is_inferred="true"} ! calcium ion transmembrane transport
 
 [Term]
+id: GO:0061862 ! cellular response to differentiation-inducing factor 2
+is_a: GO:0051716 {is_inferred="true"} ! cellular response to stimulus
+is_a: GO:1905960 {is_inferred="true"} ! response to differentiation-inducing factor 2
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
@@ -76160,17 +76165,17 @@
 is_a: GO:0043241 {is_inferred="true"} ! protein complex disassembly
 
 [Term]
-id: GO:1903013 ! response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one
+id: GO:1903013 ! response to differentiation-inducing factor 1
 is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
 is_a: GO:0045472 {is_inferred="true"} ! response to ether
 is_a: GO:1901654 {is_inferred="true"} ! response to ketone
 
 [Term]
-id: GO:1903014 ! cellular response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one
+id: GO:1903014 ! cellular response to differentiation-inducing factor 1
 is_a: GO:0071362 {is_inferred="true"} ! cellular response to ether
 is_a: GO:0071407 {is_inferred="true"} ! cellular response to organic cyclic compound
 is_a: GO:1901655 {is_inferred="true"} ! cellular response to ketone
-is_a: GO:1903013 {is_inferred="true"} ! response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one
+is_a: GO:1903013 {is_inferred="true"} ! response to differentiation-inducing factor 1
 
 [Term]
 id: GO:1903015 ! regulation of exo-alpha-sialidase activity
@@ -90243,7 +90248,7 @@
 is_a: GO:1905957 {is_inferred="true"} ! regulation of cellular response to alcohol
 
 [Term]
-id: GO:1905960 ! response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one
+id: GO:1905960 ! response to differentiation-inducing factor 2
 is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
 is_a: GO:0045472 {is_inferred="true"} ! response to ether
 is_a: GO:1901654 {is_inferred="true"} ! response to ketone
------------------------------------------------------------------------
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changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40268)
+++ go_inferences.obo	(working copy)
@@ -254,11 +254,22 @@
 is_a: GO:1904029 {is_inferred="true"} ! regulation of cyclin-dependent protein kinase activity
 
 [Term]
+id: GO:0000082 ! G1/S transition of mitotic cell cycle
+is_a: GO:0044772 {is_inferred="true"} ! mitotic cell cycle phase transition
+is_a: GO:0044843 {is_inferred="true"} ! cell cycle G1/S phase transition
+
+[Term]
 id: GO:0000083 ! regulation of transcription involved in G1/S transition of mitotic cell cycle
 is_a: GO:0006355 {is_inferred="true"} ! regulation of transcription, DNA-templated
 is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
+id: GO:0000086 ! G2/M transition of mitotic cell cycle
+is_a: GO:0044772 {is_inferred="true"} ! mitotic cell cycle phase transition
+is_a: GO:0044839 {is_inferred="true"} ! cell cycle G2/M phase transition
+is_a: GO:0045840 {is_inferred="true"} ! positive regulation of mitotic nuclear division
+
+[Term]
 id: GO:0000087 ! mitotic M phase
 is_a: GO:0098763 {is_inferred="true"} ! mitotic cell cycle phase
 
@@ -562,6 +573,7 @@
 
 [Term]
 id: GO:0000281 ! mitotic cytokinesis
+is_a: GO:0061640 {is_inferred="true"} ! cytoskeleton-dependent cytokinesis
 is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
@@ -7929,6 +7941,10 @@
 is_a: GO:0007056 {is_inferred="true"} ! spindle assembly involved in female meiosis
 
 [Term]
+id: GO:0007060 ! male meiosis chromosome segregation
+is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
+
+[Term]
 id: GO:0007063 ! regulation of sister chromatid cohesion
 is_a: GO:0033045 {is_inferred="true"} ! regulation of sister chromatid segregation
 
@@ -7992,6 +8008,10 @@
 is_a: GO:0051783 {is_inferred="true"} ! regulation of nuclear division
 
 [Term]
+id: GO:0007091 ! metaphase/anaphase transition of mitotic cell cycle
+is_a: GO:0044784 {is_inferred="true"} ! metaphase/anaphase transition of cell cycle
+
+[Term]
 id: GO:0007093 ! mitotic cell cycle checkpoint
 is_a: GO:0000075 {is_inferred="true"} ! cell cycle checkpoint
 is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
@@ -8006,6 +8026,10 @@
 is_a: GO:0007088 {is_inferred="true"} ! regulation of mitotic nuclear division
 
 [Term]
+id: GO:0007098 ! centrosome cycle
+is_a: GO:0031023 {is_inferred="true"} ! microtubule organizing center organization
+
+[Term]
 id: GO:0007100 ! mitotic centrosome separation
 is_a: GO:0051299 {is_inferred="true"} ! centrosome separation
 is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
@@ -8053,6 +8077,22 @@
 is_a: GO:0098765 {is_inferred="true"} ! meiosis II cell cycle phase
 
 [Term]
+id: GO:0007141 ! male meiosis I
+is_a: GO:0007127 {is_inferred="true"} ! meiosis I
+
+[Term]
+id: GO:0007142 ! male meiosis II
+is_a: GO:0007135 {is_inferred="true"} ! meiosis II
+
+[Term]
+id: GO:0007144 ! female meiosis I
+is_a: GO:0007127 {is_inferred="true"} ! meiosis I
+
+[Term]
+id: GO:0007147 ! female meiosis II
+is_a: GO:0007135 {is_inferred="true"} ! meiosis II
+
+[Term]
 id: GO:0007175 ! negative regulation of epidermal growth factor-activated receptor activity
 is_a: GO:0007176 {is_inferred="true"} ! regulation of epidermal growth factor-activated receptor activity
 is_a: GO:0061099 {is_inferred="true"} ! negative regulation of protein tyrosine kinase activity
@@ -8592,7 +8632,6 @@
 [Term]
 id: GO:0008328 ! ionotropic glutamate receptor complex
 is_a: GO:0034702 {is_inferred="true"} ! ion channel complex
-is_a: GO:0098802 {is_inferred="true"} ! plasma membrane receptor complex
 is_a: GO:0098878 {is_inferred="true"} ! neurotransmitter receptor complex
 
 [Term]
@@ -11544,6 +11583,7 @@
 
 [Term]
 id: GO:0010389 ! regulation of G2/M transition of mitotic cell cycle
+is_a: GO:0007088 {is_inferred="true"} ! regulation of mitotic nuclear division
 is_a: GO:1901990 {is_inferred="true"} ! regulation of mitotic cell cycle phase transition
 is_a: GO:1902749 {is_inferred="true"} ! regulation of cell cycle G2/M phase transition
 
@@ -13289,6 +13329,7 @@
 [Term]
 id: GO:0010971 ! positive regulation of G2/M transition of mitotic cell cycle
 is_a: GO:0010389 {is_inferred="true"} ! regulation of G2/M transition of mitotic cell cycle
+is_a: GO:0045840 {is_inferred="true"} ! positive regulation of mitotic nuclear division
 is_a: GO:1901992 {is_inferred="true"} ! positive regulation of mitotic cell cycle phase transition
 is_a: GO:1902751 {is_inferred="true"} ! positive regulation of cell cycle G2/M phase transition
 
@@ -16510,6 +16551,7 @@
 
 [Term]
 id: GO:0016321 ! female meiosis chromosome segregation
+is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 is_a: GO:0045132 {is_inferred="true"} ! meiotic chromosome segregation
 
 [Term]
@@ -16541,10 +16583,12 @@
 [Term]
 id: GO:0016345 ! female meiotic chromosome movement towards spindle pole
 is_a: GO:0016344 {is_inferred="true"} ! meiotic chromosome movement towards spindle pole
+is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 
 [Term]
 id: GO:0016346 ! male meiotic chromosome movement towards spindle pole
 is_a: GO:0016344 {is_inferred="true"} ! meiotic chromosome movement towards spindle pole
+is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 
 [Term]
 id: GO:0016360 ! sensory organ precursor cell fate determination
@@ -20285,8 +20329,8 @@
 
 [Term]
 id: GO:0030474 ! spindle pole body duplication
-is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
 is_a: GO:0051300 {is_inferred="true"} ! spindle pole body organization
+is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
 
 [Term]
 id: GO:0030476 ! ascospore wall assembly
@@ -21141,7 +21185,7 @@
 
 [Term]
 id: GO:0030997 ! regulation of centriole-centriole cohesion
-is_a: GO:0070507 {is_inferred="true"} ! regulation of microtubule cytoskeleton organization
+is_a: GO:0046605 {is_inferred="true"} ! regulation of centrosome cycle
 
 [Term]
 id: GO:0030999 ! linear element assembly
@@ -21182,14 +21226,17 @@
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
+id: GO:0031023 ! microtubule organizing center organization
+is_a: GO:0006996 {is_inferred="true"} ! organelle organization
+
+[Term]
 id: GO:0031024 ! interphase microtubule organizing center assembly
-is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
+is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
 
 [Term]
 id: GO:0031025 ! equatorial microtubule organizing center disassembly
-is_a: GO:0022411 {is_inferred="true"} ! cellular component disassembly
 is_a: GO:0031023 {is_inferred="true"} ! microtubule organizing center organization
-is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
+is_a: GO:1903008 {is_inferred="true"} ! organelle disassembly
 
 [Term]
 id: GO:0031026 ! glutamate synthase complex
@@ -25878,6 +25925,7 @@
 
 [Term]
 id: GO:0033206 ! meiotic cytokinesis
+is_a: GO:0061640 {is_inferred="true"} ! cytoskeleton-dependent cytokinesis
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
@@ -29909,6 +29957,10 @@
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
 
 [Term]
+id: GO:0036064 ! ciliary basal body
+is_a: GO:0005815 {is_inferred="true"} ! microtubule organizing center
+
+[Term]
 id: GO:0036079 ! purine nucleotide-sugar transport
 is_a: GO:0015780 {is_inferred="true"} ! nucleotide-sugar transport
 
@@ -40136,11 +40188,13 @@
 id: GO:0046603 ! negative regulation of mitotic centrosome separation
 is_a: GO:0045839 {is_inferred="true"} ! negative regulation of mitotic nuclear division
 is_a: GO:0046602 {is_inferred="true"} ! regulation of mitotic centrosome separation
+is_a: GO:0046606 {is_inferred="true"} ! negative regulation of centrosome cycle
 
 [Term]
 id: GO:0046604 ! positive regulation of mitotic centrosome separation
 is_a: GO:0045840 {is_inferred="true"} ! positive regulation of mitotic nuclear division
 is_a: GO:0046602 {is_inferred="true"} ! regulation of mitotic centrosome separation
+is_a: GO:0046607 {is_inferred="true"} ! positive regulation of centrosome cycle
 
 [Term]
 id: GO:0046605 ! regulation of centrosome cycle
@@ -43672,18 +43726,6 @@
 is_a: GO:0051295 {is_inferred="true"} ! establishment of meiotic spindle localization
 
 [Term]
-id: GO:0051297 ! centrosome organization
-is_a: GO:0031023 {is_inferred="true"} ! microtubule organizing center organization
-
-[Term]
-id: GO:0051298 ! centrosome duplication
-is_a: GO:0022402 {is_inferred="true"} ! cell cycle process
-
-[Term]
-id: GO:0051299 ! centrosome separation
-is_a: GO:0022402 {is_inferred="true"} ! cell cycle process
-
-[Term]
 id: GO:0051300 ! spindle pole body organization
 is_a: GO:0031023 {is_inferred="true"} ! microtubule organizing center organization
 
@@ -44593,7 +44635,6 @@
 
 [Term]
 id: GO:0051642 ! centrosome localization
-is_a: GO:0051640 {is_inferred="true"} ! organelle localization
 is_a: GO:0061842 {is_inferred="true"} ! microtubule organizing center localization
 
 [Term]
@@ -48915,10 +48956,6 @@
 is_a: GO:1902440 {is_inferred="true"} ! protein localization to mitotic spindle pole body
 
 [Term]
-id: GO:0061511 ! centriole elongation
-is_a: GO:0022402 {is_inferred="true"} ! cell cycle process
-
-[Term]
 id: GO:0061519 ! macrophage homeostasis
 is_a: GO:0001776 {is_inferred="true"} ! leukocyte homeostasis
 
@@ -49218,7 +49255,7 @@
 
 [Term]
 id: GO:0061842 ! microtubule organizing center localization
-is_a: GO:0051179 {is_inferred="true"} ! localization
+is_a: GO:0051640 {is_inferred="true"} ! organelle localization
 
 [Term]
 id: GO:0061845 ! neuron projection branch point
@@ -50508,6 +50545,7 @@
 
 [Term]
 id: GO:0070632 ! establishment of spindle pole body localization
+is_a: GO:0051656 {is_inferred="true"} ! establishment of organelle localization
 is_a: GO:0070631 {is_inferred="true"} ! spindle pole body localization
 
 [Term]
@@ -57833,8 +57871,8 @@
 
 [Term]
 id: GO:0097107 ! postsynaptic density assembly
-is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
 is_a: GO:0097106 {is_inferred="true"} ! postsynaptic density organization
+is_a: GO:0098698 {is_inferred="true"} ! postsynaptic specialization assembly
 
 [Term]
 id: GO:0097120 ! receptor localization to synapse
@@ -58812,6 +58850,37 @@
 is_a: GO:0050792 {is_inferred="true"} ! regulation of viral process
 
 [Term]
+id: GO:0098693 ! regulation of synaptic vesicle cycle
+is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
+is_a: GO:0060341 {is_inferred="true"} ! regulation of cellular localization
+
+[Term]
+id: GO:0098694 ! regulation of synaptic vesicle budding from presynaptic endocytic zone membrane
+is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
+is_a: GO:1900242 {is_inferred="true"} ! regulation of synaptic vesicle endocytosis
+
+[Term]
+id: GO:0098695 ! inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels
+is_a: GO:0005220 {is_inferred="true"} ! inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
+
+[Term]
+id: GO:0098696 ! regulation of neurotransmitter receptor localization to postsynaptic specialization membrane
+is_a: GO:0065008 {is_inferred="true"} ! regulation of biological quality
+is_a: GO:1902473 {is_inferred="true"} ! regulation of protein localization to synapse
+is_a: GO:1902683 {is_inferred="true"} ! regulation of receptor localization to synapse
+is_a: GO:1904375 {is_inferred="true"} ! regulation of protein localization to cell periphery
+is_a: GO:1905475 {is_inferred="true"} ! regulation of protein localization to membrane
+
+[Term]
+id: GO:0098697 ! ryanodine-sensitive calcium-release channel activity involved in regulation of postsynaptic cytosolic calcium levels
+is_a: GO:0005219 {is_inferred="true"} ! ryanodine-sensitive calcium-release channel activity
+
+[Term]
+id: GO:0098698 ! postsynaptic specialization assembly
+is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
+is_a: GO:0099084 {is_inferred="true"} ! postsynaptic specialization organization
+
+[Term]
 id: GO:0098700 ! neurotransmitter loading into synaptic vesicle
 is_a: GO:0006836 {is_inferred="true"} ! neurotransmitter transport
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
@@ -59265,7 +59334,7 @@
 
 [Term]
 id: GO:0098878 ! neurotransmitter receptor complex
-is_a: GO:0043235 {is_inferred="true"} ! receptor complex
+is_a: GO:0098802 {is_inferred="true"} ! plasma membrane receptor complex
 
 [Term]
 id: GO:0098879 ! structural constituent of postsynaptic specialization
@@ -59276,6 +59345,11 @@
 is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
 [Term]
+id: GO:0098881 ! exocytic insertion of neurotransmitter receptor to plasma membrane
+is_a: GO:0051668 {is_inferred="true"} ! localization within membrane
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
+
+[Term]
 id: GO:0098882 ! structural constituent of presynaptic active zone
 is_a: GO:0098918 {is_inferred="true"} ! structural constituent of synapse
 
@@ -59523,9 +59597,8 @@
 
 [Term]
 id: GO:0098943 ! neurotransmitter receptor transport, postsynaptic endosome to lysosome
-is_a: GO:0007041 {is_inferred="true"} ! lysosomal transport
+is_a: GO:0008333 {is_inferred="true"} ! endosome to lysosome transport
 is_a: GO:0016192 {is_inferred="true"} ! vesicle-mediated transport
-is_a: GO:0016197 {is_inferred="true"} ! endosomal transport
 is_a: GO:0061462 {is_inferred="true"} ! protein localization to lysosome
 is_a: GO:0072666 {is_inferred="true"} ! establishment of protein localization to vacuole
 is_a: GO:0099637 {is_inferred="true"} ! neurotransmitter receptor transport
@@ -59649,11 +59722,13 @@
 is_a: GO:0016197 {is_inferred="true"} ! endosomal transport
 is_a: GO:0035418 {is_inferred="true"} ! protein localization to synapse
 is_a: GO:0072594 {is_inferred="true"} ! establishment of protein localization to organelle
+is_a: GO:0097120 {is_inferred="true"} ! receptor localization to synapse
 is_a: GO:0099637 {is_inferred="true"} ! neurotransmitter receptor transport
 is_a: GO:1902946 {is_inferred="true"} ! protein localization to early endosome
 
 [Term]
 id: GO:0098969 ! neurotransmitter receptor transport to postsynaptic membrane
+is_a: GO:0097120 {is_inferred="true"} ! receptor localization to synapse
 is_a: GO:0098877 {is_inferred="true"} ! neurotransmitter receptor transport to plasma membrane
 is_a: GO:1903540 {is_inferred="true"} ! establishment of protein localization to postsynaptic membrane
 
@@ -59664,6 +59739,7 @@
 
 [Term]
 id: GO:0098971 ! anterograde dendritic transport of neurotransmitter receptor complex
+is_a: GO:0097120 {is_inferred="true"} ! receptor localization to synapse
 is_a: GO:0098937 {is_inferred="true"} ! anterograde dendritic transport
 
 [Term]
@@ -60422,6 +60498,12 @@
 is_a: GO:0099566 {is_inferred="true"} ! regulation of postsynaptic cytosolic calcium ion concentration
 
 [Term]
+id: GO:0099590 ! neurotransmitter receptor internalization
+is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
+is_a: GO:0051668 {is_inferred="true"} ! localization within membrane
+is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
+
+[Term]
 id: GO:0099592 ! endocytosed synaptic vesicle processing via endosome
 is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
 
@@ -60482,10 +60564,6 @@
 is_a: GO:0098953 {is_inferred="true"} ! receptor diffusion trapping
 
 [Term]
-id: GO:0099630 ! postsynaptic neurotransmitter receptor cycle
-is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
-
-[Term]
 id: GO:0099631 ! postsynaptic endocytic zone cytoplasmic component
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
 
@@ -60508,6 +60586,10 @@
 is_a: GO:0099626 {is_inferred="true"} ! voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels
 
 [Term]
+id: GO:0099637 ! neurotransmitter receptor transport
+is_a: GO:0099632 {is_inferred="true"} ! protein transport within plasma membrane
+
+[Term]
 id: GO:0099638 ! endosome to plasma membrane protein transport
 is_a: GO:0015031 {is_inferred="true"} ! protein transport
 is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
@@ -60542,6 +60624,7 @@
 
 [Term]
 id: GO:0099645 ! neurotransmitter receptor localization to postsynaptic specialization membrane
+is_a: GO:0097120 {is_inferred="true"} ! receptor localization to synapse
 is_a: GO:0099633 {is_inferred="true"} ! protein localization to postsynaptic specialization membrane
 
 [Term]
@@ -69005,8 +69088,7 @@
 is_a: GO:0032847 {is_inferred="true"} ! regulation of cellular pH reduction
 is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
 is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
-is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
-is_a: GO:0060341 {is_inferred="true"} ! regulation of cellular localization
+is_a: GO:0098693 {is_inferred="true"} ! regulation of synaptic vesicle cycle
 
 [Term]
 id: GO:1901547 ! negative regulation of synaptic vesicle lumen acidification
@@ -76574,12 +76656,12 @@
 [Term]
 id: GO:1903126 ! negative regulation of centriole-centriole cohesion
 is_a: GO:0030997 {is_inferred="true"} ! regulation of centriole-centriole cohesion
-is_a: GO:0051494 {is_inferred="true"} ! negative regulation of cytoskeleton organization
+is_a: GO:0046606 {is_inferred="true"} ! negative regulation of centrosome cycle
 
 [Term]
 id: GO:1903127 ! positive regulation of centriole-centriole cohesion
 is_a: GO:0030997 {is_inferred="true"} ! regulation of centriole-centriole cohesion
-is_a: GO:0051495 {is_inferred="true"} ! positive regulation of cytoskeleton organization
+is_a: GO:0046607 {is_inferred="true"} ! positive regulation of centrosome cycle
 
 [Term]
 id: GO:1903131 ! mononuclear cell differentiation
@@ -77929,6 +78011,7 @@
 
 [Term]
 id: GO:1903421 ! regulation of synaptic vesicle recycling
+is_a: GO:0098693 {is_inferred="true"} ! regulation of synaptic vesicle cycle
 is_a: GO:1902803 {is_inferred="true"} ! regulation of synaptic vesicle transport
 
 [Term]
@@ -81533,8 +81616,8 @@
 
 [Term]
 id: GO:1904185 ! equatorial microtubule organizing center assembly
-is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
 is_a: GO:0031023 {is_inferred="true"} ! microtubule organizing center organization
+is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
 
 [Term]
 id: GO:1904186 ! post-anaphase microtubule array organization
@@ -92634,6 +92717,7 @@
 id: GO:2000300 ! regulation of synaptic vesicle exocytosis
 is_a: GO:0017158 {is_inferred="true"} ! regulation of calcium ion-dependent exocytosis
 is_a: GO:0046928 {is_inferred="true"} ! regulation of neurotransmitter secretion
+is_a: GO:0098693 {is_inferred="true"} ! regulation of synaptic vesicle cycle
 is_a: GO:1902803 {is_inferred="true"} ! regulation of synaptic vesicle transport
 
 [Term]
@@ -95118,8 +95202,7 @@
 
 [Term]
 id: GO:2000807 ! regulation of synaptic vesicle clustering
-is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
-is_a: GO:0060341 {is_inferred="true"} ! regulation of cellular localization
+is_a: GO:0098693 {is_inferred="true"} ! regulation of synaptic vesicle cycle
 
 [Term]
 id: GO:2000808 ! negative regulation of synaptic vesicle clustering
------------------------------------------------------------------------
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changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40241)
+++ go_inferences.obo	(working copy)
@@ -759,6 +759,12 @@
 is_a: GO:1905369 {is_inferred="true"} ! endopeptidase complex
 
 [Term]
+id: GO:0000506 ! glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
+is_a: GO:0044425 {is_inferred="true"} ! membrane part
+is_a: GO:0044432 {is_inferred="true"} ! endoplasmic reticulum part
+is_a: GO:1990234 {is_inferred="true"} ! transferase complex
+
+[Term]
 id: GO:0000706 ! meiotic DNA double-strand break processing
 is_a: GO:0000729 {is_inferred="true"} ! DNA double-strand break processing
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
------------------------------------------------------------------------
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changes in entailments

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changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40228)
+++ go_inferences.obo	(working copy)
@@ -8570,6 +8570,11 @@
 is_a: GO:0098802 {is_inferred="true"} ! plasma membrane receptor complex
 
 [Term]
+id: GO:0008315 ! G2/MI transition of meiotic cell cycle
+is_a: GO:0044771 {is_inferred="true"} ! meiotic cell cycle phase transition
+is_a: GO:0044839 {is_inferred="true"} ! cell cycle G2/M phase transition
+
+[Term]
 id: GO:0008320 ! protein transmembrane transporter activity
 is_a: GO:0008565 {is_inferred="true"} ! protein transporter activity
 is_a: GO:1904680 {is_inferred="true"} ! peptide transmembrane transporter activity
------------------------------------------------------------------------
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changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40206)
+++ go_inferences.obo	(working copy)
@@ -60920,6 +60920,24 @@
 is_a: GO:0017053 {is_inferred="true"} ! transcriptional repressor complex
 
 [Term]
+id: GO:0110002 ! regulation of tRNA methylation
+is_a: GO:2000235 {is_inferred="true"} ! regulation of tRNA processing
+
+[Term]
+id: GO:0110003 ! regulation of tRNA C5-cytosine methylation
+is_a: GO:0110002 {is_inferred="true"} ! regulation of tRNA methylation
+
+[Term]
+id: GO:0110004 ! positive regulation of tRNA methylation
+is_a: GO:0110002 {is_inferred="true"} ! regulation of tRNA methylation
+is_a: GO:2000237 {is_inferred="true"} ! positive regulation of tRNA processing
+
+[Term]
+id: GO:0110005 ! positive regulation of tRNA C5-cytosine methylation
+is_a: GO:0110003 {is_inferred="true"} ! regulation of tRNA C5-cytosine methylation
+is_a: GO:0110004 {is_inferred="true"} ! positive regulation of tRNA methylation
+
+[Term]
 id: GO:0120006 ! regulation of glutamatergic neuron differentiation
 is_a: GO:0045664 {is_inferred="true"} ! regulation of neuron differentiation
 
@@ -69305,11 +69323,6 @@
 is_a: GO:0022857 {is_inferred="true"} ! transmembrane transporter activity
 
 [Term]
-id: GO:1901619 ! tRNA methylation in response to nitrogen starvation
-is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
-is_a: GO:1901698 {is_inferred="true"} ! response to nitrogen compound
-
-[Term]
 id: GO:1901620 ! regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
 is_a: GO:0008589 {is_inferred="true"} ! regulation of smoothened signaling pathway
 is_a: GO:0045995 {is_inferred="true"} ! regulation of embryonic development
@@ -69408,20 +69421,6 @@
 is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
 
 [Term]
-id: GO:1901643 ! regulation of tRNA methylation in response to nitrogen starvation
-is_a: GO:0010646 {is_inferred="true"} ! regulation of cell communication
-is_a: GO:0032107 {is_inferred="true"} ! regulation of response to nutrient levels
-is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
-is_a: GO:2000235 {is_inferred="true"} ! regulation of tRNA processing
-
-[Term]
-id: GO:1901644 ! positive regulation of tRNA methylation in response to nitrogen starvation
-is_a: GO:0010647 {is_inferred="true"} ! positive regulation of cell communication
-is_a: GO:0032109 {is_inferred="true"} ! positive regulation of response to nutrient levels
-is_a: GO:1901643 {is_inferred="true"} ! regulation of tRNA methylation in response to nitrogen starvation
-is_a: GO:2000237 {is_inferred="true"} ! positive regulation of tRNA processing
-
-[Term]
 id: GO:1901645 ! regulation of synoviocyte proliferation
 is_a: GO:0042127 {is_inferred="true"} ! regulation of cell proliferation
 
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40203)
+++ go_inferences.obo	(working copy)
@@ -60293,18 +60293,18 @@
 is_a: GO:0050804 {is_inferred="true"} ! modulation of synaptic transmission
 
 [Term]
-id: GO:0099550 ! trans-synaptic signalling, modulating synaptic transmission
+id: GO:0099550 ! trans-synaptic signaling, modulating synaptic transmission
 is_a: GO:0050804 {is_inferred="true"} ! modulation of synaptic transmission
 
 [Term]
 id: GO:0099551 ! trans-synaptic signaling by neuropeptide, modulating synaptic transmission
 is_a: GO:0099540 {is_inferred="true"} ! trans-synaptic signaling by neuropeptide
-is_a: GO:0099550 {is_inferred="true"} ! trans-synaptic signalling, modulating synaptic transmission
+is_a: GO:0099550 {is_inferred="true"} ! trans-synaptic signaling, modulating synaptic transmission
 
 [Term]
 id: GO:0099552 ! trans-synaptic signaling by lipid, modulating synaptic transmission
 is_a: GO:0099541 {is_inferred="true"} ! trans-synaptic signaling by lipid
-is_a: GO:0099550 {is_inferred="true"} ! trans-synaptic signalling, modulating synaptic transmission
+is_a: GO:0099550 {is_inferred="true"} ! trans-synaptic signaling, modulating synaptic transmission
 
 [Term]
 id: GO:0099553 ! trans-synaptic signaling by endocannabinoid, modulating synaptic transmission
@@ -60313,7 +60313,7 @@
 
 [Term]
 id: GO:0099554 ! trans-synaptic signaling by soluble gas, modulating synaptic transmission
-is_a: GO:0099550 {is_inferred="true"} ! trans-synaptic signalling, modulating synaptic transmission
+is_a: GO:0099550 {is_inferred="true"} ! trans-synaptic signaling, modulating synaptic transmission
 
 [Term]
 id: GO:0099555 ! trans-synaptic signaling by nitric oxide, modulating synaptic transmission
@@ -60326,7 +60326,7 @@
 [Term]
 id: GO:0099557 ! trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission
 is_a: GO:0099545 {is_inferred="true"} ! trans-synaptic signaling by trans-synaptic complex
-is_a: GO:0099550 {is_inferred="true"} ! trans-synaptic signalling, modulating synaptic transmission
+is_a: GO:0099550 {is_inferred="true"} ! trans-synaptic signaling, modulating synaptic transmission
 
 [Term]
 id: GO:0099564 ! modification of synaptic structure, modulating synaptic transmission
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40094)
+++ go_inferences.obo	(working copy)
@@ -398,8 +398,7 @@
 
 [Term]
 id: GO:0000169 ! activation of MAPK activity involved in osmosensory signaling pathway
-is_a: GO:0047484 {is_inferred="true"} ! regulation of response to osmotic stress
-is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
+is_a: GO:0120027 {is_inferred="true"} ! regulation of osmosensory signaling pathway
 
 [Term]
 id: GO:0000172 ! ribonuclease MRP complex
@@ -407,8 +406,7 @@
 
 [Term]
 id: GO:0000173 ! inactivation of MAPK activity involved in osmosensory signaling pathway
-is_a: GO:0047484 {is_inferred="true"} ! regulation of response to osmotic stress
-is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
+is_a: GO:0120028 {is_inferred="true"} ! negative regulation of osmosensory signaling pathway
 
 [Term]
 id: GO:0000176 ! nuclear exosome (RNase complex)
@@ -61001,6 +60999,21 @@
 is_a: GO:0042995 {is_inferred="true"} ! cell projection
 
 [Term]
+id: GO:0120027 ! regulation of osmosensory signaling pathway
+is_a: GO:0009966 {is_inferred="true"} ! regulation of signal transduction
+is_a: GO:0047484 {is_inferred="true"} ! regulation of response to osmotic stress
+is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
+
+[Term]
+id: GO:0120028 ! negative regulation of osmosensory signaling pathway
+is_a: GO:0009968 {is_inferred="true"} ! negative regulation of signal transduction
+is_a: GO:0120027 {is_inferred="true"} ! regulation of osmosensory signaling pathway
+
+[Term]
+id: GO:0120029 ! hydrogen ion export across plasma membrane
+is_a: GO:1902600 {is_inferred="true"} ! hydrogen ion transmembrane transport
+
+[Term]
 id: GO:0140009 ! L-aspartate import across plasma membrane
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 is_a: GO:0089712 {is_inferred="true"} ! L-aspartate transmembrane transport
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40092)
+++ go_inferences.obo	(working copy)
@@ -90998,8 +90998,8 @@
 
 [Term]
 id: GO:1990771 ! clathrin-dependent extracellular exosome endocytosis
-is_a: GO:0006858 {is_inferred="true"} ! extracellular transport
 is_a: GO:0051650 {is_inferred="true"} ! establishment of vesicle localization
+is_a: GO:0072583 {is_inferred="true"} ! clathrin-dependent endocytosis
 
 [Term]
 id: GO:1990779 ! glycoprotein Ib-IX-V complex
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40064)
+++ go_inferences.obo	(working copy)
@@ -30257,11 +30257,6 @@
 is_a: GO:1901367 {is_inferred="true"} ! response to L-cysteine
 
 [Term]
-id: GO:0036347 ! glutathione import into cell
-is_a: GO:0034635 {is_inferred="true"} ! glutathione transport
-is_a: GO:0098657 {is_inferred="true"} ! import into cell
-
-[Term]
 id: GO:0036375 ! Kibra-Ex-Mer complex
 is_a: GO:0044464 {is_inferred="true"} ! cell part
 
@@ -34895,18 +34890,6 @@
 is_a: GO:0000175 {is_inferred="true"} ! 3'-5'-exoribonuclease activity
 
 [Term]
-id: GO:0044755 ! pantothenate import into cell
-is_a: GO:0098657 {is_inferred="true"} ! import into cell
-
-[Term]
-id: GO:0044756 ! biotin import into cell
-is_a: GO:0098657 {is_inferred="true"} ! import into cell
-
-[Term]
-id: GO:0044757 ! dethiobiotin import into cell
-is_a: GO:0098657 {is_inferred="true"} ! import into cell
-
-[Term]
 id: GO:0044764 ! multi-organism cellular process
 is_a: GO:0009987 {is_inferred="true"} ! cellular process
 is_a: GO:0051704 {is_inferred="true"} ! multi-organism process
@@ -48891,15 +48874,6 @@
 is_a: GO:0006270 {is_inferred="true"} ! DNA replication initiation
 
 [Term]
-id: GO:0061488 ! adenine import into cell
-is_a: GO:0015853 {is_inferred="true"} ! adenine transport
-is_a: GO:0098657 {is_inferred="true"} ! import into cell
-
-[Term]
-id: GO:0061489 ! guanine import into cell
-is_a: GO:0098657 {is_inferred="true"} ! import into cell
-
-[Term]
 id: GO:0061494 ! gamma-tubulin large complex, mitotic spindle pole body
 is_a: GO:0055032 {is_inferred="true"} ! gamma-tubulin large complex, spindle pole body
 
@@ -58114,10 +58088,6 @@
 is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
 
 [Term]
-id: GO:0097319 ! carbohydrate import into cell
-is_a: GO:0098657 {is_inferred="true"} ! import into cell
-
-[Term]
 id: GO:0097327 ! response to antineoplastic agent
 is_a: GO:0042493 {is_inferred="true"} ! response to drug
 
@@ -58208,21 +58178,6 @@
 is_a: GO:1901545 {is_inferred="true"} ! response to raffinose
 
 [Term]
-id: GO:0097404 ! succinate import into cell
-is_a: GO:0015744 {is_inferred="true"} ! succinate transport
-is_a: GO:0098657 {is_inferred="true"} ! import into cell
-
-[Term]
-id: GO:0097405 ! malate import into cell
-is_a: GO:0015743 {is_inferred="true"} ! malate transport
-is_a: GO:0098657 {is_inferred="true"} ! import into cell
-
-[Term]
-id: GO:0097406 ! malonic acid import into cell
-is_a: GO:0098657 {is_inferred="true"} ! import into cell
-is_a: GO:1900752 {is_inferred="true"} ! malonic acid transport
-
-[Term]
 id: GO:0097410 ! hippocampal interneuron differentiation
 is_a: GO:0021879 {is_inferred="true"} ! forebrain neuron differentiation
 is_a: GO:0021895 {is_inferred="true"} ! cerebral cortex neuron differentiation
@@ -58253,10 +58208,6 @@
 is_a: GO:0097386 {is_inferred="true"} ! glial cell projection
 
 [Term]
-id: GO:0097459 ! iron ion import into cell
-is_a: GO:0098659 {is_inferred="true"} ! inorganic cation import into cell
-
-[Term]
 id: GO:0097466 ! ubiquitin-dependent glycoprotein ERAD pathway
 is_a: GO:1904587 {is_inferred="true"} ! response to glycoprotein
 
@@ -58775,13 +58726,14 @@
 is_a: GO:0006810 {is_inferred="true"} ! transport
 
 [Term]
-id: GO:0098658 ! inorganic anion import into cell
-is_a: GO:0099587 {is_inferred="true"} ! inorganic ion import into cell
+id: GO:0098658 ! inorganic anion import across plasma membrane
+is_a: GO:0098661 {is_inferred="true"} ! inorganic anion transmembrane transport
+is_a: GO:0099587 {is_inferred="true"} ! inorganic ion import across plasma membrane
 
 [Term]
-id: GO:0098659 ! inorganic cation import into cell
-is_a: GO:0006812 {is_inferred="true"} ! cation transport
-is_a: GO:0099587 {is_inferred="true"} ! inorganic ion import into cell
+id: GO:0098659 ! inorganic cation import across plasma membrane
+is_a: GO:0098662 {is_inferred="true"} ! inorganic cation transmembrane transport
+is_a: GO:0099587 {is_inferred="true"} ! inorganic ion import across plasma membrane
 
 [Term]
 id: GO:0098660 ! inorganic ion transmembrane transport
@@ -58862,7 +58814,7 @@
 
 [Term]
 id: GO:0098702 ! adenine import across plasma membrane
-is_a: GO:0061488 {is_inferred="true"} ! adenine import into cell
+is_a: GO:0015853 {is_inferred="true"} ! adenine transport
 is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
 is_a: GO:1904823 {is_inferred="true"} ! purine nucleobase transmembrane transport
 
@@ -58869,46 +58821,41 @@
 [Term]
 id: GO:0098703 ! calcium ion import across plasma membrane
 is_a: GO:0097553 {is_inferred="true"} ! calcium ion transmembrane import into cytosol
-is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
-is_a: GO:1990035 {is_inferred="true"} ! calcium ion import into cell
+is_a: GO:0098659 {is_inferred="true"} ! inorganic cation import across plasma membrane
 
 [Term]
 id: GO:0098704 ! carbohydrate import across plasma membrane
 is_a: GO:0034219 {is_inferred="true"} ! carbohydrate transmembrane transport
-is_a: GO:0097319 {is_inferred="true"} ! carbohydrate import into cell
 is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
 
 [Term]
 id: GO:0098705 ! copper ion import across plasma membrane
+is_a: GO:0015677 {is_inferred="true"} ! copper ion import
 is_a: GO:0015679 {is_inferred="true"} ! plasma membrane copper ion transport
-is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
-is_a: GO:1902861 {is_inferred="true"} ! copper ion import into cell
+is_a: GO:0098659 {is_inferred="true"} ! inorganic cation import across plasma membrane
 
 [Term]
 id: GO:0098706 ! ferric iron import across plasma membrane
+is_a: GO:0033216 {is_inferred="true"} ! ferric iron import
 is_a: GO:0098711 {is_inferred="true"} ! iron ion import across plasma membrane
 
 [Term]
 id: GO:0098707 ! ferrous iron import across plasma membrane
-is_a: GO:0097460 {is_inferred="true"} ! ferrous iron import into cell
+is_a: GO:0070627 {is_inferred="true"} ! ferrous iron import
 is_a: GO:0098711 {is_inferred="true"} ! iron ion import across plasma membrane
 is_a: GO:1903874 {is_inferred="true"} ! ferrous iron transmembrane transport
 
 [Term]
 id: GO:0098708 ! glucose import across plasma membrane
-is_a: GO:0061490 {is_inferred="true"} ! glucose import into cell
-is_a: GO:0098704 {is_inferred="true"} ! carbohydrate import across plasma membrane
 is_a: GO:1904659 {is_inferred="true"} ! glucose transmembrane transport
 
 [Term]
 id: GO:0098709 ! glutathione import across plasma membrane
 is_a: GO:0034775 {is_inferred="true"} ! glutathione transmembrane transport
-is_a: GO:0036347 {is_inferred="true"} ! glutathione import into cell
 is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
 
 [Term]
 id: GO:0098710 ! guanine import across plasma membrane
-is_a: GO:0061489 {is_inferred="true"} ! guanine import into cell
 is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
 is_a: GO:1903716 {is_inferred="true"} ! guanine transmembrane transport
 
@@ -58915,8 +58862,8 @@
 [Term]
 id: GO:0098711 ! iron ion import across plasma membrane
 is_a: GO:0034755 {is_inferred="true"} ! iron ion transmembrane transport
-is_a: GO:0097459 {is_inferred="true"} ! iron ion import into cell
-is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
+is_a: GO:0097286 {is_inferred="true"} ! iron ion import
+is_a: GO:0098659 {is_inferred="true"} ! inorganic cation import across plasma membrane
 
 [Term]
 id: GO:0098712 ! L-glutamate import across plasma membrane
@@ -58926,33 +58873,30 @@
 
 [Term]
 id: GO:0098713 ! leucine import across plasma membrane
+is_a: GO:0060356 {is_inferred="true"} ! leucine import
 is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
 is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
-is_a: GO:1990122 {is_inferred="true"} ! leucine import into cell
 
 [Term]
 id: GO:0098714 ! malate import across plasma membrane
 is_a: GO:0071423 {is_inferred="true"} ! malate transmembrane transport
-is_a: GO:0097405 {is_inferred="true"} ! malate import into cell
 is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
 
 [Term]
 id: GO:0098715 ! malonic acid import across plasma membrane
-is_a: GO:0097406 {is_inferred="true"} ! malonic acid import into cell
 is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
 is_a: GO:1901553 {is_inferred="true"} ! malonic acid transmembrane transport
 
 [Term]
 id: GO:0098716 ! nickel cation import across plasma membrane
-is_a: GO:0090509 {is_inferred="true"} ! nickel cation import into cell
-is_a: GO:0098659 {is_inferred="true"} ! inorganic cation import into cell
-is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
+is_a: GO:0035444 {is_inferred="true"} ! nickel cation transmembrane transport
+is_a: GO:0098659 {is_inferred="true"} ! inorganic cation import across plasma membrane
 
 [Term]
 id: GO:0098717 ! pantothenate import across plasma membrane
 is_a: GO:0015887 {is_inferred="true"} ! pantothenate transmembrane transport
-is_a: GO:0044755 {is_inferred="true"} ! pantothenate import into cell
 is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
+is_a: GO:1901688 {is_inferred="true"} ! pantothenate import
 
 [Term]
 id: GO:0098718 ! serine import across plasma membrane
@@ -58962,20 +58906,17 @@
 
 [Term]
 id: GO:0098719 ! sodium ion import across plasma membrane
-is_a: GO:0098659 {is_inferred="true"} ! inorganic cation import into cell
-is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
-is_a: GO:1990118 {is_inferred="true"} ! sodium ion import into cell
+is_a: GO:0097369 {is_inferred="true"} ! sodium ion import
+is_a: GO:0098659 {is_inferred="true"} ! inorganic cation import across plasma membrane
 
 [Term]
 id: GO:0098720 ! succinate import across plasma membrane
 is_a: GO:0071422 {is_inferred="true"} ! succinate transmembrane transport
-is_a: GO:0097404 {is_inferred="true"} ! succinate import into cell
 is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
 
 [Term]
 id: GO:0098721 ! uracil import across plasma membrane
 is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
-is_a: GO:1902431 {is_inferred="true"} ! uracil import into cell
 is_a: GO:1903791 {is_inferred="true"} ! uracil transmembrane transport
 
 [Term]
@@ -60462,9 +60403,9 @@
 is_a: GO:0099588 {is_inferred="true"} ! positive regulation of postsynaptic cytosolic calcium concentration
 
 [Term]
-id: GO:0099587 ! inorganic ion import into cell
-is_a: GO:0006811 {is_inferred="true"} ! ion transport
-is_a: GO:0098657 {is_inferred="true"} ! import into cell
+id: GO:0099587 ! inorganic ion import across plasma membrane
+is_a: GO:0098660 {is_inferred="true"} ! inorganic ion transmembrane transport
+is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
 
 [Term]
 id: GO:0099588 ! positive regulation of postsynaptic cytosolic calcium concentration
@@ -73444,17 +73385,13 @@
 is_a: GO:1902992 {is_inferred="true"} ! negative regulation of amyloid precursor protein catabolic process
 
 [Term]
-id: GO:1902431 ! uracil import into cell
-is_a: GO:0015857 {is_inferred="true"} ! uracil transport
-is_a: GO:0098657 {is_inferred="true"} ! import into cell
-
-[Term]
 id: GO:1902433 ! positive regulation of water channel activity involved in maintenance of lens transparency
 is_a: GO:1902429 {is_inferred="true"} ! positive regulation of water channel activity
 
 [Term]
-id: GO:1902434 ! sulfate import into cell
-is_a: GO:0008272 {is_inferred="true"} ! sulfate transport
+id: GO:1902434 ! sulfate import across plasma membrane
+is_a: GO:0098658 {is_inferred="true"} ! inorganic anion import across plasma membrane
+is_a: GO:1902358 {is_inferred="true"} ! sulfate transmembrane transport
 
 [Term]
 id: GO:1902435 ! regulation of male mating behavior
@@ -75384,11 +75321,6 @@
 is_a: GO:1902858 {is_inferred="true"} ! propionyl-CoA metabolic process
 
 [Term]
-id: GO:1902861 ! copper ion import into cell
-is_a: GO:0015677 {is_inferred="true"} ! copper ion import
-is_a: GO:0098659 {is_inferred="true"} ! inorganic cation import into cell
-
-[Term]
 id: GO:1902863 ! regulation of embryonic camera-type eye development
 is_a: GO:0045995 {is_inferred="true"} ! regulation of embryonic development
 
@@ -76363,8 +76295,9 @@
 is_a: GO:0071550 {is_inferred="true"} ! death-inducing signaling complex assembly
 
 [Term]
-id: GO:1903075 ! pyridoxine import into cell
-is_a: GO:0031923 {is_inferred="true"} ! pyridoxine transport
+id: GO:1903075 ! pyridoxine import across plasma membrane
+is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
+is_a: GO:1903092 {is_inferred="true"} ! pyridoxine transmembrane transport
 
 [Term]
 id: GO:1903076 ! regulation of protein localization to plasma membrane
@@ -76626,15 +76559,6 @@
 is_a: GO:0051495 {is_inferred="true"} ! positive regulation of cytoskeleton organization
 
 [Term]
-id: GO:1903129 ! negative regulation of leucine import into cell
-is_a: GO:0060358 {is_inferred="true"} ! negative regulation of leucine import
-
-[Term]
-id: GO:1903130 ! positive regulation of leucine import into cell
-is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
-is_a: GO:0060357 {is_inferred="true"} ! regulation of leucine import
-
-[Term]
 id: GO:1903131 ! mononuclear cell differentiation
 is_a: GO:0002521 {is_inferred="true"} ! leukocyte differentiation
 
@@ -77186,8 +77110,9 @@
 is_a: GO:1903256 {is_inferred="true"} ! selenoneine metabolic process
 
 [Term]
-id: GO:1903258 ! sorbose import into cell
-is_a: GO:0008645 {is_inferred="true"} ! hexose transport
+id: GO:1903258 ! sorbose import across plasma membrane
+is_a: GO:0035428 {is_inferred="true"} ! hexose transmembrane transport
+is_a: GO:0098704 {is_inferred="true"} ! carbohydrate import across plasma membrane
 
 [Term]
 id: GO:1903259 ! exon-exon junction complex disassembly
@@ -80679,20 +80604,6 @@
 is_a: GO:1903414 {is_inferred="true"} ! iron cation export
 
 [Term]
-id: GO:1903989 ! regulation of ferrous iron import into cell
-is_a: GO:1900390 {is_inferred="true"} ! regulation of iron ion import
-
-[Term]
-id: GO:1903990 ! negative regulation of ferrous iron import into cell
-is_a: GO:0034757 {is_inferred="true"} ! negative regulation of iron ion transport
-is_a: GO:1903989 {is_inferred="true"} ! regulation of ferrous iron import into cell
-
-[Term]
-id: GO:1903991 ! positive regulation of ferrous iron import into cell
-is_a: GO:0034758 {is_inferred="true"} ! positive regulation of iron ion transport
-is_a: GO:1903989 {is_inferred="true"} ! regulation of ferrous iron import into cell
-
-[Term]
 id: GO:1903995 ! regulation of non-membrane spanning protein tyrosine kinase activity
 is_a: GO:0061097 {is_inferred="true"} ! regulation of protein tyrosine kinase activity
 
@@ -82830,18 +82741,16 @@
 [Term]
 id: GO:1904438 ! regulation of ferrous iron import across plasma membrane
 is_a: GO:0034759 {is_inferred="true"} ! regulation of iron ion transmembrane transport
-is_a: GO:1903989 {is_inferred="true"} ! regulation of ferrous iron import into cell
+is_a: GO:1900390 {is_inferred="true"} ! regulation of iron ion import
 
 [Term]
 id: GO:1904439 ! negative regulation of ferrous iron import across plasma membrane
 is_a: GO:0034760 {is_inferred="true"} ! negative regulation of iron ion transmembrane transport
-is_a: GO:1903990 {is_inferred="true"} ! negative regulation of ferrous iron import into cell
 is_a: GO:1904438 {is_inferred="true"} ! regulation of ferrous iron import across plasma membrane
 
 [Term]
 id: GO:1904440 ! positive regulation of ferrous iron import across plasma membrane
 is_a: GO:0034761 {is_inferred="true"} ! positive regulation of iron ion transmembrane transport
-is_a: GO:1903991 {is_inferred="true"} ! positive regulation of ferrous iron import into cell
 is_a: GO:1904438 {is_inferred="true"} ! regulation of ferrous iron import across plasma membrane
 
 [Term]
@@ -82884,8 +82793,11 @@
 is_a: GO:2000020 {is_inferred="true"} ! positive regulation of male gonad development
 
 [Term]
-id: GO:1904447 ! folic acid import into cell
+id: GO:1904447 ! folic acid import across plasma membrane
 is_a: GO:0015884 {is_inferred="true"} ! folic acid transport
+is_a: GO:0035461 {is_inferred="true"} ! vitamin transmembrane transport
+is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
+is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
 id: GO:1904448 ! regulation of aspartate secretion
@@ -84014,7 +83926,7 @@
 
 [Term]
 id: GO:1904679 ! myo-inositol import across plasma membrane
-is_a: GO:0097357 {is_inferred="true"} ! myo-inositol import into cell
+is_a: GO:0015798 {is_inferred="true"} ! myo-inositol transport
 is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
 
 [Term]
@@ -85636,7 +85548,7 @@
 
 [Term]
 id: GO:1905011 ! transmembrane phosphate ion transport from cytosol to vacuole
-is_a: GO:0007034 {is_inferred="true"} ! vacuolar transport
+is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
 is_a: GO:0035435 {is_inferred="true"} ! phosphate ion transmembrane transport
 
 [Term]
@@ -86264,14 +86176,14 @@
 [Term]
 id: GO:1905135 ! biotin import across plasma membrane
 is_a: GO:0035461 {is_inferred="true"} ! vitamin transmembrane transport
-is_a: GO:0044756 {is_inferred="true"} ! biotin import into cell
 is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
+is_a: GO:1901689 {is_inferred="true"} ! biotin import
 is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
 id: GO:1905136 ! dethiobiotin import across plasma membrane
-is_a: GO:0044757 {is_inferred="true"} ! dethiobiotin import into cell
 is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
+is_a: GO:1901690 {is_inferred="true"} ! dethiobiotin import
 is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
@@ -88160,7 +88072,7 @@
 
 [Term]
 id: GO:1905533 ! negative regulation of leucine import across plasma membrane
-is_a: GO:1903129 {is_inferred="true"} ! negative regulation of leucine import into cell
+is_a: GO:0060358 {is_inferred="true"} ! negative regulation of leucine import
 is_a: GO:1903960 {is_inferred="true"} ! negative regulation of anion transmembrane transport
 is_a: GO:1904063 {is_inferred="true"} ! negative regulation of cation transmembrane transport
 is_a: GO:1905532 {is_inferred="true"} ! regulation of leucine import across plasma membrane
@@ -88167,7 +88079,7 @@
 
 [Term]
 id: GO:1905534 ! positive regulation of leucine import across plasma membrane
-is_a: GO:1903130 {is_inferred="true"} ! positive regulation of leucine import into cell
+is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
 is_a: GO:1903961 {is_inferred="true"} ! positive regulation of anion transmembrane transport
 is_a: GO:1904064 {is_inferred="true"} ! positive regulation of cation transmembrane transport
 is_a: GO:1905532 {is_inferred="true"} ! regulation of leucine import across plasma membrane
@@ -90273,11 +90185,6 @@
 is_a: GO:1901660 {is_inferred="true"} ! calcium ion export
 
 [Term]
-id: GO:1990035 ! calcium ion import into cell
-is_a: GO:0070509 {is_inferred="true"} ! calcium ion import
-is_a: GO:0098659 {is_inferred="true"} ! inorganic cation import into cell
-
-[Term]
 id: GO:1990036 ! calcium ion import into sarcoplasmic reticulum
 is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
 is_a: GO:0070296 {is_inferred="true"} ! sarcoplasmic reticulum calcium ion transport
@@ -90387,11 +90294,6 @@
 is_a: GO:0044422 {is_inferred="true"} ! organelle part
 
 [Term]
-id: GO:1990122 ! leucine import into cell
-is_a: GO:0060356 {is_inferred="true"} ! leucine import
-is_a: GO:0098657 {is_inferred="true"} ! import into cell
-
-[Term]
 id: GO:1990126 ! retrograde transport, endosome to plasma membrane
 is_a: GO:0098876 {is_inferred="true"} ! vesicle-mediated transport to the plasma membrane
 
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40034)
+++ go_inferences.obo	(working copy)
@@ -45069,8 +45069,8 @@
 
 [Term]
 id: GO:0051933 ! amino acid neurotransmitter reuptake
+is_a: GO:0043090 {is_inferred="true"} ! amino acid import
 is_a: GO:0098810 {is_inferred="true"} ! neurotransmitter reuptake
-is_a: GO:1902837 {is_inferred="true"} ! amino acid import into cell
 
 [Term]
 id: GO:0051934 ! catecholamine uptake involved in synaptic transmission
@@ -45080,7 +45080,6 @@
 [Term]
 id: GO:0051935 ! glutamate reuptake
 is_a: GO:0051933 {is_inferred="true"} ! amino acid neurotransmitter reuptake
-is_a: GO:1990123 {is_inferred="true"} ! L-glutamate import into cell
 
 [Term]
 id: GO:0051936 ! gamma-aminobutyric acid reuptake
@@ -45134,6 +45133,7 @@
 id: GO:0051946 ! regulation of glutamate uptake involved in transmission of nerve impulse
 is_a: GO:0051941 {is_inferred="true"} ! regulation of amino acid uptake involved in synaptic transmission
 is_a: GO:1900920 {is_inferred="true"} ! regulation of L-glutamate import
+is_a: GO:1903789 {is_inferred="true"} ! regulation of amino acid transmembrane transport
 
 [Term]
 id: GO:0051947 ! regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse
@@ -45144,6 +45144,7 @@
 is_a: GO:0051942 {is_inferred="true"} ! negative regulation of amino acid uptake involved in synaptic transmission
 is_a: GO:0051946 {is_inferred="true"} ! regulation of glutamate uptake involved in transmission of nerve impulse
 is_a: GO:1900921 {is_inferred="true"} ! negative regulation of L-glutamate import
+is_a: GO:1903960 {is_inferred="true"} ! negative regulation of anion transmembrane transport
 
 [Term]
 id: GO:0051949 ! negative regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse
@@ -45160,6 +45161,7 @@
 is_a: GO:0051943 {is_inferred="true"} ! positive regulation of amino acid uptake involved in synaptic transmission
 is_a: GO:0051946 {is_inferred="true"} ! regulation of glutamate uptake involved in transmission of nerve impulse
 is_a: GO:1900922 {is_inferred="true"} ! positive regulation of L-glutamate import
+is_a: GO:1903961 {is_inferred="true"} ! positive regulation of anion transmembrane transport
 
 [Term]
 id: GO:0051955 ! regulation of amino acid transport
@@ -48898,10 +48900,6 @@
 is_a: GO:0098657 {is_inferred="true"} ! import into cell
 
 [Term]
-id: GO:0061491 ! serine import into cell
-is_a: GO:1902837 {is_inferred="true"} ! amino acid import into cell
-
-[Term]
 id: GO:0061494 ! gamma-tubulin large complex, mitotic spindle pole body
 is_a: GO:0055032 {is_inferred="true"} ! gamma-tubulin large complex, spindle pole body
 
@@ -55999,7 +55997,6 @@
 id: GO:0089718 ! amino acid import across plasma membrane
 is_a: GO:0044745 {is_inferred="true"} ! amino acid transmembrane import
 is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
-is_a: GO:1902837 {is_inferred="true"} ! amino acid import into cell
 
 [Term]
 id: GO:0089721 ! phosphoenolpyruvate transmembrane transporter activity
@@ -57460,8 +57457,7 @@
 [Term]
 id: GO:0090453 ! aspartate transmembrane import into vacuole
 is_a: GO:0015810 {is_inferred="true"} ! aspartate transport
-is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
-is_a: GO:0044745 {is_inferred="true"} ! amino acid transmembrane import
+is_a: GO:0032975 {is_inferred="true"} ! amino acid transmembrane import into vacuole
 
 [Term]
 id: GO:0090454 ! glutamate transmembrane import into vacuole
@@ -57579,25 +57575,25 @@
 
 [Term]
 id: GO:0090513 ! L-histidine transmembrane import into vacuole
+is_a: GO:0061460 {is_inferred="true"} ! L-histidine import
 is_a: GO:0089709 {is_inferred="true"} ! L-histidine transmembrane transport
-is_a: GO:1903810 {is_inferred="true"} ! L-histidine import into cell
 
 [Term]
 id: GO:0090514 ! L-tyrosine transmembrane import into vacuole
+is_a: GO:0036232 {is_inferred="true"} ! L-tyrosine import
 is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
-is_a: GO:1903808 {is_inferred="true"} ! L-tyrosine import into cell
 
 [Term]
 id: GO:0090515 ! L-glutamate transmembrane import into vacuole
 is_a: GO:0089711 {is_inferred="true"} ! L-glutamate transmembrane transport
-is_a: GO:1903802 {is_inferred="true"} ! L-glutamate(1-) import into cell
+is_a: GO:1903802 {is_inferred="true"} ! L-glutamate(1-) import across plasma membrane
 
 [Term]
 id: GO:0090516 ! L-serine transmembrane import into vacuole
+is_a: GO:0090479 {is_inferred="true"} ! L-serine import
 is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
-is_a: GO:1903812 {is_inferred="true"} ! L-serine import into cell
 
 [Term]
 id: GO:0090517 ! L-lysine transmembrane import into vacuole
@@ -58363,15 +58359,21 @@
 
 [Term]
 id: GO:0097638 ! L-arginine import across plasma membrane
+is_a: GO:0043091 {is_inferred="true"} ! L-arginine import
 is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
+is_a: GO:1903400 {is_inferred="true"} ! L-arginine transmembrane transport
 
 [Term]
 id: GO:0097639 ! L-lysine import across plasma membrane
+is_a: GO:0061461 {is_inferred="true"} ! L-lysine import
 is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
+is_a: GO:1903401 {is_inferred="true"} ! L-lysine transmembrane transport
 
 [Term]
 id: GO:0097640 ! L-ornithine import across plasma membrane
+is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
+is_a: GO:1903352 {is_inferred="true"} ! L-ornithine transmembrane transport
 
 [Term]
 id: GO:0097648 ! G-protein coupled receptor complex
@@ -58920,7 +58922,7 @@
 id: GO:0098712 ! L-glutamate import across plasma membrane
 is_a: GO:0089711 {is_inferred="true"} ! L-glutamate transmembrane transport
 is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
-is_a: GO:1990123 {is_inferred="true"} ! L-glutamate import into cell
+is_a: GO:1903802 {is_inferred="true"} ! L-glutamate(1-) import across plasma membrane
 
 [Term]
 id: GO:0098713 ! leucine import across plasma membrane
@@ -58954,8 +58956,8 @@
 
 [Term]
 id: GO:0098718 ! serine import across plasma membrane
-is_a: GO:0061491 {is_inferred="true"} ! serine import into cell
 is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
+is_a: GO:0090478 {is_inferred="true"} ! serine import
 is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 
 [Term]
@@ -61061,6 +61063,7 @@
 id: GO:0140009 ! L-aspartate import across plasma membrane
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 is_a: GO:0089712 {is_inferred="true"} ! L-aspartate transmembrane transport
+is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
 
 [Term]
 id: GO:0140010 ! D-aspartate transmembrane transporter activity
@@ -61071,6 +61074,11 @@
 is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
+id: GO:0140016 ! D-aspartate import across plasma membrane
+is_a: GO:0070779 {is_inferred="true"} ! D-aspartate import
+is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
+
+[Term]
 id: GO:1900000 ! regulation of anthocyanin catabolic process
 is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
 is_a: GO:0031537 {is_inferred="true"} ! regulation of anthocyanin metabolic process
@@ -74941,11 +74949,6 @@
 is_a: GO:1902762 {is_inferred="true"} ! regulation of embryonic skeletal joint development
 
 [Term]
-id: GO:1902765 ! L-arginine import into cell
-is_a: GO:0043091 {is_inferred="true"} ! L-arginine import
-is_a: GO:1902837 {is_inferred="true"} ! amino acid import into cell
-
-[Term]
 id: GO:1902766 ! skeletal muscle satellite cell migration
 is_a: GO:0016477 {is_inferred="true"} ! cell migration
 
@@ -75224,25 +75227,6 @@
 is_a: GO:1903337 {is_inferred="true"} ! positive regulation of vacuolar transport
 
 [Term]
-id: GO:1902825 ! proline import into cell
-is_a: GO:0015824 {is_inferred="true"} ! proline transport
-is_a: GO:1902837 {is_inferred="true"} ! amino acid import into cell
-
-[Term]
-id: GO:1902826 ! regulation of L-arginine import into cell
-is_a: GO:0010963 {is_inferred="true"} ! regulation of L-arginine import
-
-[Term]
-id: GO:1902827 ! negative regulation of L-arginine import into cell
-is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
-is_a: GO:1902826 {is_inferred="true"} ! regulation of L-arginine import into cell
-
-[Term]
-id: GO:1902828 ! positive regulation of L-arginine import into cell
-is_a: GO:1901042 {is_inferred="true"} ! positive regulation of L-arginine import
-is_a: GO:1902826 {is_inferred="true"} ! regulation of L-arginine import into cell
-
-[Term]
 id: GO:1902829 ! regulation of spinal cord association neuron differentiation
 is_a: GO:0045664 {is_inferred="true"} ! regulation of neuron differentiation
 
@@ -75267,26 +75251,27 @@
 is_a: GO:2000179 {is_inferred="true"} ! positive regulation of neural precursor cell proliferation
 
 [Term]
-id: GO:1902834 ! regulation of proline import into cell
+id: GO:1902834 ! regulation of proline import across plasma membrane
 is_a: GO:0010958 {is_inferred="true"} ! regulation of amino acid import
 is_a: GO:0070881 {is_inferred="true"} ! regulation of proline transport
+is_a: GO:1903789 {is_inferred="true"} ! regulation of amino acid transmembrane transport
+is_a: GO:1904062 {is_inferred="true"} ! regulation of cation transmembrane transport
 
 [Term]
-id: GO:1902835 ! negative regulation of proline import into cell
+id: GO:1902835 ! negative regulation of proline import across plasma membrane
 is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
-is_a: GO:1902834 {is_inferred="true"} ! regulation of proline import into cell
+is_a: GO:1902834 {is_inferred="true"} ! regulation of proline import across plasma membrane
+is_a: GO:1903960 {is_inferred="true"} ! negative regulation of anion transmembrane transport
+is_a: GO:1904063 {is_inferred="true"} ! negative regulation of cation transmembrane transport
 
 [Term]
-id: GO:1902836 ! positive regulation of proline import into cell
+id: GO:1902836 ! positive regulation of proline import across plasma membrane
 is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
-is_a: GO:1902834 {is_inferred="true"} ! regulation of proline import into cell
+is_a: GO:1902834 {is_inferred="true"} ! regulation of proline import across plasma membrane
+is_a: GO:1903961 {is_inferred="true"} ! positive regulation of anion transmembrane transport
+is_a: GO:1904064 {is_inferred="true"} ! positive regulation of cation transmembrane transport
 
 [Term]
-id: GO:1902837 ! amino acid import into cell
-is_a: GO:0043090 {is_inferred="true"} ! amino acid import
-is_a: GO:0098657 {is_inferred="true"} ! import into cell
-
-[Term]
 id: GO:1902838 ! regulation of nuclear migration along microtubule
 is_a: GO:1902513 {is_inferred="true"} ! regulation of organelle transport along microtubule
 
@@ -76641,18 +76626,13 @@
 is_a: GO:0051495 {is_inferred="true"} ! positive regulation of cytoskeleton organization
 
 [Term]
-id: GO:1903128 ! regulation of leucine import into cell
-is_a: GO:0060357 {is_inferred="true"} ! regulation of leucine import
-
-[Term]
 id: GO:1903129 ! negative regulation of leucine import into cell
 is_a: GO:0060358 {is_inferred="true"} ! negative regulation of leucine import
-is_a: GO:1903128 {is_inferred="true"} ! regulation of leucine import into cell
 
 [Term]
 id: GO:1903130 ! positive regulation of leucine import into cell
 is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
-is_a: GO:1903128 {is_inferred="true"} ! regulation of leucine import into cell
+is_a: GO:0060357 {is_inferred="true"} ! regulation of leucine import
 
 [Term]
 id: GO:1903131 ! mononuclear cell differentiation
@@ -77956,15 +77936,6 @@
 is_a: GO:0072593 {is_inferred="true"} ! reactive oxygen species metabolic process
 
 [Term]
-id: GO:1903410 ! L-lysine import into cell
-is_a: GO:0061461 {is_inferred="true"} ! L-lysine import
-
-[Term]
-id: GO:1903411 ! L-ornithine import into cell
-is_a: GO:0015822 {is_inferred="true"} ! ornithine transport
-is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
-
-[Term]
 id: GO:1903412 ! response to bile acid
 is_a: GO:0001101 {is_inferred="true"} ! response to acid chemical
 is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
@@ -79297,8 +79268,10 @@
 is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
 
 [Term]
-id: GO:1903692 ! methionine import into cell
+id: GO:1903692 ! methionine import across plasma membrane
 is_a: GO:0044690 {is_inferred="true"} ! methionine import
+is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 
 [Term]
 id: GO:1903693 ! regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation
@@ -79794,63 +79767,75 @@
 is_a: GO:2000637 {is_inferred="true"} ! positive regulation of gene silencing by miRNA
 
 [Term]
-id: GO:1903801 ! L-leucine import into cell
+id: GO:1903801 ! L-leucine import across membrane
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
-is_a: GO:0060356 {is_inferred="true"} ! leucine import
+is_a: GO:0098713 {is_inferred="true"} ! leucine import across plasma membrane
+is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
 
 [Term]
-id: GO:1903802 ! L-glutamate(1-) import into cell
+id: GO:1903802 ! L-glutamate(1-) import across plasma membrane
 is_a: GO:0051938 {is_inferred="true"} ! L-glutamate import
 
 [Term]
-id: GO:1903803 ! L-glutamine import into cell
+id: GO:1903803 ! L-glutamine import across plasma membrane
 is_a: GO:0036229 {is_inferred="true"} ! L-glutamine import
+is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
+is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
 
 [Term]
-id: GO:1903804 ! glycine import into cell
+id: GO:1903804 ! glycine import into across plasma membrane
 is_a: GO:0036233 {is_inferred="true"} ! glycine import
 
 [Term]
-id: GO:1903805 ! L-valine import into cell
+id: GO:1903805 ! L-valine import across plasma membrane
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
+is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
 is_a: GO:0090468 {is_inferred="true"} ! valine import
+is_a: GO:1903785 {is_inferred="true"} ! L-valine transmembrane transport
 
 [Term]
-id: GO:1903806 ! L-isoleucine import into cell
+id: GO:1903806 ! L-isoleucine import across plasma membrane
+is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
 is_a: GO:0090477 {is_inferred="true"} ! L-isoleucine import
+is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
+is_a: GO:1903714 {is_inferred="true"} ! isoleucine transmembrane transport
 
 [Term]
-id: GO:1903807 ! L-threonine import into cell
+id: GO:1903807 ! L-threonine import across plasma membrane
 is_a: GO:0036231 {is_inferred="true"} ! L-threonine import
+is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
+is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
 
 [Term]
-id: GO:1903808 ! L-tyrosine import into cell
+id: GO:1903808 ! L-tyrosine import across plasma membrane
 is_a: GO:0036232 {is_inferred="true"} ! L-tyrosine import
+is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
+is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
 
 [Term]
-id: GO:1903809 ! L-proline import into cell
-is_a: GO:0015824 {is_inferred="true"} ! proline transport
-is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
-
-[Term]
-id: GO:1903810 ! L-histidine import into cell
+id: GO:1903810 ! L-histidine import across plasma membrane
 is_a: GO:0061460 {is_inferred="true"} ! L-histidine import
+is_a: GO:0089709 {is_inferred="true"} ! L-histidine transmembrane transport
+is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
 
 [Term]
-id: GO:1903811 ! L-asparagine import into cell
+id: GO:1903811 ! L-asparagine import across plasma membrane
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
+is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
 is_a: GO:0090469 {is_inferred="true"} ! asparagine import
+is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
+is_a: GO:1903713 {is_inferred="true"} ! asparagine transmembrane transport
 
 [Term]
-id: GO:1903812 ! L-serine import into cell
+id: GO:1903812 ! L-serine import across plasma membrane
 is_a: GO:0090479 {is_inferred="true"} ! L-serine import
+is_a: GO:0098718 {is_inferred="true"} ! serine import across plasma membrane
+is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
 
 [Term]
-id: GO:1903813 ! L-methionine import into cell
-is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
-is_a: GO:1903692 {is_inferred="true"} ! methionine import into cell
-
-[Term]
 id: GO:1903814 ! regulation of collecting lymphatic vessel constriction
 is_a: GO:0044057 {is_inferred="true"} ! regulation of system process
 is_a: GO:0090066 {is_inferred="true"} ! regulation of anatomical structure size
@@ -82020,7 +82005,7 @@
 
 [Term]
 id: GO:1904271 ! L-proline import across plasma membrane
-is_a: GO:1903809 {is_inferred="true"} ! L-proline import into cell
+is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 is_a: GO:1904555 {is_inferred="true"} ! L-proline transmembrane transport
 is_a: GO:1905647 {is_inferred="true"} ! proline import across plasma membrane
 
@@ -85630,18 +85615,24 @@
 is_a: GO:1905005 {is_inferred="true"} ! regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
 
 [Term]
-id: GO:1905008 ! regulation of L-lysine import into cell
+id: GO:1905008 ! regulation of L-lysine import across plasma membrane
 is_a: GO:0010805 {is_inferred="true"} ! regulation of lysine import
+is_a: GO:1903789 {is_inferred="true"} ! regulation of amino acid transmembrane transport
+is_a: GO:1904062 {is_inferred="true"} ! regulation of cation transmembrane transport
 
 [Term]
-id: GO:1905009 ! negative regulation of L-lysine import into cell
+id: GO:1905009 ! negative regulation of L-lysine import across plasma membrane
 is_a: GO:0010806 {is_inferred="true"} ! negative regulation of lysine import
-is_a: GO:1905008 {is_inferred="true"} ! regulation of L-lysine import into cell
+is_a: GO:1903960 {is_inferred="true"} ! negative regulation of anion transmembrane transport
+is_a: GO:1904063 {is_inferred="true"} ! negative regulation of cation transmembrane transport
+is_a: GO:1905008 {is_inferred="true"} ! regulation of L-lysine import across plasma membrane
 
 [Term]
-id: GO:1905010 ! positive regulation of L-lysine import into cell
+id: GO:1905010 ! positive regulation of L-lysine import across plasma membrane
 is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
-is_a: GO:1905008 {is_inferred="true"} ! regulation of L-lysine import into cell
+is_a: GO:1903961 {is_inferred="true"} ! positive regulation of anion transmembrane transport
+is_a: GO:1904064 {is_inferred="true"} ! positive regulation of cation transmembrane transport
+is_a: GO:1905008 {is_inferred="true"} ! regulation of L-lysine import across plasma membrane
 
 [Term]
 id: GO:1905011 ! transmembrane phosphate ion transport from cytosol to vacuole
@@ -88163,7 +88154,7 @@
 
 [Term]
 id: GO:1905532 ! regulation of leucine import across plasma membrane
-is_a: GO:1903128 {is_inferred="true"} ! regulation of leucine import into cell
+is_a: GO:0060357 {is_inferred="true"} ! regulation of leucine import
 is_a: GO:1903789 {is_inferred="true"} ! regulation of amino acid transmembrane transport
 is_a: GO:1904062 {is_inferred="true"} ! regulation of cation transmembrane transport
 
@@ -88210,13 +88201,13 @@
 
 [Term]
 id: GO:1905541 ! regulation of L-arginine import across plasma membrane
-is_a: GO:1902826 {is_inferred="true"} ! regulation of L-arginine import into cell
+is_a: GO:0010963 {is_inferred="true"} ! regulation of L-arginine import
 is_a: GO:1903789 {is_inferred="true"} ! regulation of amino acid transmembrane transport
 is_a: GO:1904062 {is_inferred="true"} ! regulation of cation transmembrane transport
 
 [Term]
 id: GO:1905542 ! negative regulation of L-arginine import across plasma membrane
-is_a: GO:1902827 {is_inferred="true"} ! negative regulation of L-arginine import into cell
+is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
 is_a: GO:1903960 {is_inferred="true"} ! negative regulation of anion transmembrane transport
 is_a: GO:1904063 {is_inferred="true"} ! negative regulation of cation transmembrane transport
 is_a: GO:1905541 {is_inferred="true"} ! regulation of L-arginine import across plasma membrane
@@ -88228,10 +88219,9 @@
 
 [Term]
 id: GO:1905544 ! L-methionine import across plasma membrane
-is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
-is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
+is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
-is_a: GO:1903813 {is_inferred="true"} ! L-methionine import into cell
+is_a: GO:1903692 {is_inferred="true"} ! methionine import across plasma membrane
 
 [Term]
 id: GO:1905546 ! cellular response to phenylpropanoid
@@ -88425,7 +88415,7 @@
 
 [Term]
 id: GO:1905589 ! positive regulation of L-arginine import across plasma membrane
-is_a: GO:1902828 {is_inferred="true"} ! positive regulation of L-arginine import into cell
+is_a: GO:1901042 {is_inferred="true"} ! positive regulation of L-arginine import
 is_a: GO:1903961 {is_inferred="true"} ! positive regulation of anion transmembrane transport
 is_a: GO:1904064 {is_inferred="true"} ! positive regulation of cation transmembrane transport
 is_a: GO:1905541 {is_inferred="true"} ! regulation of L-arginine import across plasma membrane
@@ -88722,7 +88712,6 @@
 id: GO:1905647 ! proline import across plasma membrane
 is_a: GO:0035524 {is_inferred="true"} ! proline transmembrane transport
 is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
-is_a: GO:1902825 {is_inferred="true"} ! proline import into cell
 
 [Term]
 id: GO:1905648 ! regulation of shell calcification
@@ -89080,22 +89069,16 @@
 
 [Term]
 id: GO:1905735 ! regulation of L-proline import across plasma membrane
-is_a: GO:1902834 {is_inferred="true"} ! regulation of proline import into cell
-is_a: GO:1903789 {is_inferred="true"} ! regulation of amino acid transmembrane transport
-is_a: GO:1904062 {is_inferred="true"} ! regulation of cation transmembrane transport
+is_a: GO:1902834 {is_inferred="true"} ! regulation of proline import across plasma membrane
 
 [Term]
 id: GO:1905736 ! negative regulation of L-proline import across plasma membrane
-is_a: GO:1902835 {is_inferred="true"} ! negative regulation of proline import into cell
-is_a: GO:1903960 {is_inferred="true"} ! negative regulation of anion transmembrane transport
-is_a: GO:1904063 {is_inferred="true"} ! negative regulation of cation transmembrane transport
+is_a: GO:1902835 {is_inferred="true"} ! negative regulation of proline import across plasma membrane
 is_a: GO:1905735 {is_inferred="true"} ! regulation of L-proline import across plasma membrane
 
 [Term]
 id: GO:1905737 ! positive regulation of L-proline import across plasma membrane
-is_a: GO:1902836 {is_inferred="true"} ! positive regulation of proline import into cell
-is_a: GO:1903961 {is_inferred="true"} ! positive regulation of anion transmembrane transport
-is_a: GO:1904064 {is_inferred="true"} ! positive regulation of cation transmembrane transport
+is_a: GO:1902836 {is_inferred="true"} ! positive regulation of proline import across plasma membrane
 is_a: GO:1905735 {is_inferred="true"} ! regulation of L-proline import across plasma membrane
 
 [Term]
@@ -90406,14 +90389,9 @@
 [Term]
 id: GO:1990122 ! leucine import into cell
 is_a: GO:0060356 {is_inferred="true"} ! leucine import
-is_a: GO:1902837 {is_inferred="true"} ! amino acid import into cell
+is_a: GO:0098657 {is_inferred="true"} ! import into cell
 
 [Term]
-id: GO:1990123 ! L-glutamate import into cell
-is_a: GO:1902837 {is_inferred="true"} ! amino acid import into cell
-is_a: GO:1903802 {is_inferred="true"} ! L-glutamate(1-) import into cell
-
-[Term]
 id: GO:1990126 ! retrograde transport, endosome to plasma membrane
 is_a: GO:0098876 {is_inferred="true"} ! vesicle-mediated transport to the plasma membrane
 
@@ -90967,8 +90945,7 @@
 
 [Term]
 id: GO:1990591 ! asparagine transmembrane import into vacuole
-is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
-is_a: GO:0044745 {is_inferred="true"} ! amino acid transmembrane import
+is_a: GO:0032975 {is_inferred="true"} ! amino acid transmembrane import into vacuole
 is_a: GO:0090469 {is_inferred="true"} ! asparagine import
 is_a: GO:1903713 {is_inferred="true"} ! asparagine transmembrane transport
 
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40027)
+++ go_inferences.obo	(working copy)
@@ -60988,7 +60988,7 @@
 is_a: GO:0120006 {is_inferred="true"} ! regulation of glutamatergic neuron differentiation
 
 [Term]
-id: GO:0120008 ! positive  regulation of glutamatergic neuron differentiation
+id: GO:0120008 ! positive regulation of glutamatergic neuron differentiation
 is_a: GO:0045666 {is_inferred="true"} ! positive regulation of neuron differentiation
 is_a: GO:0120006 {is_inferred="true"} ! regulation of glutamatergic neuron differentiation
 
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40006)
+++ go_inferences.obo	(working copy)
@@ -559,6 +559,10 @@
 is_a: GO:0098800 {is_inferred="true"} ! inner mitochondrial membrane protein complex
 
 [Term]
+id: GO:0000278 ! mitotic cell cycle
+is_a: GO:0007049 {is_inferred="true"} ! cell cycle
+
+[Term]
 id: GO:0000281 ! mitotic cytokinesis
 is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
@@ -7930,10 +7934,6 @@
 is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
-id: GO:0007067 ! mitotic nuclear division
-is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
-
-[Term]
 id: GO:0007072 ! positive regulation of transcription involved in exit from mitosis
 is_a: GO:0045893 {is_inferred="true"} ! positive regulation of transcription, DNA-templated
 is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
@@ -30654,7 +30654,7 @@
 [Term]
 id: GO:0040001 ! establishment of mitotic spindle localization
 is_a: GO:0051293 {is_inferred="true"} ! establishment of spindle localization
-is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
+is_a: GO:1902850 {is_inferred="true"} ! microtubule cytoskeleton organization involved in mitosis
 
 [Term]
 id: GO:0040014 ! regulation of multicellular organism growth
@@ -30676,6 +30676,7 @@
 [Term]
 id: GO:0040020 ! regulation of meiotic nuclear division
 is_a: GO:0010564 {is_inferred="true"} ! regulation of cell cycle process
+is_a: GO:0051445 {is_inferred="true"} ! regulation of meiotic cell cycle
 
 [Term]
 id: GO:0040023 ! establishment of nucleus localization
@@ -43736,6 +43737,10 @@
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
+id: GO:0051321 ! meiotic cell cycle
+is_a: GO:0007049 {is_inferred="true"} ! cell cycle
+
+[Term]
 id: GO:0051327 ! meiotic M phase
 is_a: GO:0098762 {is_inferred="true"} ! meiotic cell cycle phase
 
@@ -46148,7 +46153,7 @@
 
 [Term]
 id: GO:0060236 ! regulation of mitotic spindle organization
-is_a: GO:0007088 {is_inferred="true"} ! regulation of mitotic nuclear division
+is_a: GO:0007346 {is_inferred="true"} ! regulation of mitotic cell cycle
 is_a: GO:0090224 {is_inferred="true"} ! regulation of spindle organization
 
 [Term]
@@ -60949,6 +60954,10 @@
 is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
+id: GO:0101026 ! nuclear membrane biogenesis involved in mitotic nuclear division
+is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
+
+[Term]
 id: GO:0101028 ! positive regulation of liquid surface tension
 is_a: GO:0050828 {is_inferred="true"} ! regulation of liquid surface tension
 
@@ -61058,6 +61067,10 @@
 is_a: GO:0015556 {is_inferred="true"} ! C4-dicarboxylate transmembrane transporter activity
 
 [Term]
+id: GO:0140014 ! mitotic nuclear division
+is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
+
+[Term]
 id: GO:1900000 ! regulation of anthocyanin catabolic process
 is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
 is_a: GO:0031537 {is_inferred="true"} ! regulation of anthocyanin metabolic process
@@ -69585,6 +69598,7 @@
 
 [Term]
 id: GO:1901673 ! regulation of mitotic spindle assembly
+is_a: GO:0007088 {is_inferred="true"} ! regulation of mitotic nuclear division
 is_a: GO:0060236 {is_inferred="true"} ! regulation of mitotic spindle organization
 is_a: GO:0090169 {is_inferred="true"} ! regulation of spindle assembly
 
@@ -84055,8 +84069,9 @@
 
 [Term]
 id: GO:1904687 ! positive regulation of mitotic spindle disassembly
-is_a: GO:0045840 {is_inferred="true"} ! positive regulation of mitotic nuclear division
+is_a: GO:0045931 {is_inferred="true"} ! positive regulation of mitotic cell cycle
 is_a: GO:0051495 {is_inferred="true"} ! positive regulation of cytoskeleton organization
+is_a: GO:0090068 {is_inferred="true"} ! positive regulation of cell cycle process
 is_a: GO:1904686 {is_inferred="true"} ! regulation of mitotic spindle disassembly
 
 [Term]
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 40003)
+++ go_inferences.obo	(working copy)
@@ -60965,6 +60965,11 @@
 is_a: GO:0044445 {is_inferred="true"} ! cytosolic part
 
 [Term]
+id: GO:0110001 ! toxin-antitoxin complex
+is_a: GO:0005667 {is_inferred="true"} ! transcription factor complex
+is_a: GO:0017053 {is_inferred="true"} ! transcriptional repressor complex
+
+[Term]
 id: GO:0120006 ! regulation of glutamatergic neuron differentiation
 is_a: GO:0045664 {is_inferred="true"} ! regulation of neuron differentiation
 
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 39907)
+++ go_inferences.obo	(working copy)
@@ -390,13 +390,11 @@
 
 [Term]
 id: GO:0000167 ! activation of MAPKKK activity involved in osmosensory signaling pathway
-is_a: GO:0047484 {is_inferred="true"} ! regulation of response to osmotic stress
-is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
+is_a: GO:0000168 {is_inferred="true"} ! activation of MAPKK activity involved in osmosensory signaling pathway
 
 [Term]
 id: GO:0000168 ! activation of MAPKK activity involved in osmosensory signaling pathway
-is_a: GO:0047484 {is_inferred="true"} ! regulation of response to osmotic stress
-is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
+is_a: GO:0000169 {is_inferred="true"} ! activation of MAPK activity involved in osmosensory signaling pathway
 
 [Term]
 id: GO:0000169 ! activation of MAPK activity involved in osmosensory signaling pathway
@@ -424,14 +422,11 @@
 
 [Term]
 id: GO:0000185 ! activation of MAPKKK activity
-is_a: GO:0043405 {is_inferred="true"} ! regulation of MAP kinase activity
-is_a: GO:0043410 {is_inferred="true"} ! positive regulation of MAPK cascade
-is_a: GO:0071902 {is_inferred="true"} ! positive regulation of protein serine/threonine kinase activity
+is_a: GO:0043406 {is_inferred="true"} ! positive regulation of MAP kinase activity
 
 [Term]
 id: GO:0000186 ! activation of MAPKK activity
-is_a: GO:0043405 {is_inferred="true"} ! regulation of MAP kinase activity
-is_a: GO:0043410 {is_inferred="true"} ! positive regulation of MAPK cascade
+is_a: GO:0043406 {is_inferred="true"} ! positive regulation of MAP kinase activity
 
 [Term]
 id: GO:0000196 ! MAPK cascade involved in cell wall organization or biogenesis
@@ -439,11 +434,11 @@
 
 [Term]
 id: GO:0000197 ! activation of MAPKKK activity involved in cell wall organization or biogenesis
-is_a: GO:1903139 {is_inferred="true"} ! positive regulation of MAPK cascade involved in cell wall organization or biogenesis
+is_a: GO:0000198 {is_inferred="true"} ! activation of MAPKK activity involved in cell wall organization or biogenesis
 
 [Term]
 id: GO:0000198 ! activation of MAPKK activity involved in cell wall organization or biogenesis
-is_a: GO:1903139 {is_inferred="true"} ! positive regulation of MAPK cascade involved in cell wall organization or biogenesis
+is_a: GO:0000199 {is_inferred="true"} ! activation of MAPK activity involved in cell wall organization or biogenesis
 
 [Term]
 id: GO:0000199 ! activation of MAPK activity involved in cell wall organization or biogenesis
@@ -8102,8 +8097,7 @@
 
 [Term]
 id: GO:0007256 ! activation of JNKK activity
-is_a: GO:0043506 {is_inferred="true"} ! regulation of JUN kinase activity
-is_a: GO:0046330 {is_inferred="true"} ! positive regulation of JNK cascade
+is_a: GO:0043507 {is_inferred="true"} ! positive regulation of JUN kinase activity
 
 [Term]
 id: GO:0007267 ! cell-cell signaling
@@ -8724,9 +8718,8 @@
 
 [Term]
 id: GO:0008588 ! release of cytoplasmic sequestered NF-kappaB
-is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
+is_a: GO:0042347 {is_inferred="true"} ! negative regulation of NF-kappaB import into nucleus
 is_a: GO:0065008 {is_inferred="true"} ! regulation of biological quality
-is_a: GO:1903828 {is_inferred="true"} ! negative regulation of cellular protein localization
 
 [Term]
 id: GO:0008589 ! regulation of smoothened signaling pathway
@@ -11768,6 +11761,7 @@
 
 [Term]
 id: GO:0010524 ! positive regulation of calcium ion transport into cytosol
+is_a: GO:0007204 {is_inferred="true"} ! positive regulation of cytosolic calcium ion concentration
 is_a: GO:0010522 {is_inferred="true"} ! regulation of calcium ion transport into cytosol
 is_a: GO:0032846 {is_inferred="true"} ! positive regulation of homeostatic process
 is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
@@ -11822,6 +11816,8 @@
 [Term]
 id: GO:0010536 ! positive regulation of activation of Janus kinase activity
 is_a: GO:0010533 {is_inferred="true"} ! regulation of activation of Janus kinase activity
+is_a: GO:0045860 {is_inferred="true"} ! positive regulation of protein kinase activity
+is_a: GO:0046427 {is_inferred="true"} ! positive regulation of JAK-STAT cascade
 is_a: GO:0050731 {is_inferred="true"} ! positive regulation of peptidyl-tyrosine phosphorylation
 
 [Term]
@@ -20605,6 +20601,7 @@
 
 [Term]
 id: GO:0030712 ! negative regulation of border follicle cell delamination
+is_a: GO:0022408 {is_inferred="true"} ! negative regulation of cell-cell adhesion
 is_a: GO:0022409 {is_inferred="true"} ! positive regulation of cell-cell adhesion
 is_a: GO:0030710 {is_inferred="true"} ! regulation of border follicle cell delamination
 is_a: GO:0030857 {is_inferred="true"} ! negative regulation of epithelial cell differentiation
@@ -22511,6 +22508,7 @@
 [Term]
 id: GO:0031936 ! negative regulation of chromatin silencing
 is_a: GO:0031935 {is_inferred="true"} ! regulation of chromatin silencing
+is_a: GO:0045892 {is_inferred="true"} ! negative regulation of transcription, DNA-templated
 is_a: GO:0060969 {is_inferred="true"} ! negative regulation of gene silencing
 is_a: GO:1905268 {is_inferred="true"} ! negative regulation of chromatin organization
 
@@ -24876,6 +24874,7 @@
 is_a: GO:0032845 {is_inferred="true"} ! negative regulation of homeostatic process
 is_a: GO:0032847 {is_inferred="true"} ! regulation of cellular pH reduction
 is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
+is_a: GO:0051452 {is_inferred="true"} ! intracellular pH reduction
 is_a: GO:0051454 {is_inferred="true"} ! intracellular pH elevation
 
 [Term]
@@ -27239,9 +27238,9 @@
 
 [Term]
 id: GO:0034123 ! positive regulation of toll-like receptor signaling pathway
-is_a: GO:0002684 {is_inferred="true"} ! positive regulation of immune system process
 is_a: GO:0009967 {is_inferred="true"} ! positive regulation of signal transduction
 is_a: GO:0034121 {is_inferred="true"} ! regulation of toll-like receptor signaling pathway
+is_a: GO:0045089 {is_inferred="true"} ! positive regulation of innate immune response
 
 [Term]
 id: GO:0034124 ! regulation of MyD88-dependent toll-like receptor signaling pathway
@@ -28947,6 +28946,14 @@
 is_a: GO:0000165 {is_inferred="true"} ! MAPK cascade
 
 [Term]
+id: GO:0035421 ! activation of MAPKK activity involved in innate immune response
+is_a: GO:0035419 {is_inferred="true"} ! activation of MAPK activity involved in innate immune response
+
+[Term]
+id: GO:0035422 ! activation of MAPKKK activity involved in innate immune response
+is_a: GO:0035421 {is_inferred="true"} ! activation of MAPKK activity involved in innate immune response
+
+[Term]
 id: GO:0035423 ! inactivation of MAPK activity involved in innate immune response
 is_a: GO:0045824 {is_inferred="true"} ! negative regulation of innate immune response
 
@@ -30509,6 +30516,10 @@
 is_a: GO:0098802 {is_inferred="true"} ! plasma membrane receptor complex
 
 [Term]
+id: GO:0038176 ! positive regulation of SREBP signaling pathway in response to decreased oxygen levels
+is_a: GO:1901522 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
+
+[Term]
 id: GO:0038197 ! type I interferon receptor complex
 is_a: GO:0098802 {is_inferred="true"} ! plasma membrane receptor complex
 
@@ -31967,8 +31978,7 @@
 
 [Term]
 id: GO:0042655 ! activation of JNKKK activity
-is_a: GO:0043506 {is_inferred="true"} ! regulation of JUN kinase activity
-is_a: GO:0046330 {is_inferred="true"} ! positive regulation of JNK cascade
+is_a: GO:0043507 {is_inferred="true"} ! positive regulation of JUN kinase activity
 
 [Term]
 id: GO:0042659 ! regulation of cell fate specification
@@ -37133,6 +37143,7 @@
 [Term]
 id: GO:0045756 ! positive regulation of initiation of acetate catabolic process by acetate
 is_a: GO:0045147 {is_inferred="true"} ! regulation of initiation of acetate catabolic process by acetate
+is_a: GO:0045754 {is_inferred="true"} ! positive regulation of acetate catabolic process
 is_a: GO:1901459 {is_inferred="true"} ! positive regulation of response to acetate
 
 [Term]
@@ -37600,6 +37611,7 @@
 id: GO:0045906 ! negative regulation of vasoconstriction
 is_a: GO:0019229 {is_inferred="true"} ! regulation of vasoconstriction
 is_a: GO:0097755 {is_inferred="true"} ! positive regulation of blood vessel diameter
+is_a: GO:0097756 {is_inferred="true"} ! negative regulation of blood vessel diameter
 is_a: GO:1903523 {is_inferred="true"} ! negative regulation of blood circulation
 
 [Term]
@@ -42756,8 +42768,8 @@
 
 [Term]
 id: GO:0050857 ! positive regulation of antigen receptor-mediated signaling pathway
-is_a: GO:0002684 {is_inferred="true"} ! positive regulation of immune system process
 is_a: GO:0009967 {is_inferred="true"} ! positive regulation of signal transduction
+is_a: GO:0050778 {is_inferred="true"} ! positive regulation of immune response
 is_a: GO:0050854 {is_inferred="true"} ! regulation of antigen receptor-mediated signaling pathway
 
 [Term]
@@ -43257,8 +43269,8 @@
 
 [Term]
 id: GO:0051127 ! positive regulation of actin nucleation
+is_a: GO:0030838 {is_inferred="true"} ! positive regulation of actin filament polymerization
 is_a: GO:0051125 {is_inferred="true"} ! regulation of actin nucleation
-is_a: GO:1902905 {is_inferred="true"} ! positive regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0051133 ! regulation of NK T cell activation
@@ -43618,6 +43630,7 @@
 id: GO:0051280 ! negative regulation of release of sequestered calcium ion into cytosol
 is_a: GO:0010523 {is_inferred="true"} ! negative regulation of calcium ion transport into cytosol
 is_a: GO:0051279 {is_inferred="true"} ! regulation of release of sequestered calcium ion into cytosol
+is_a: GO:0051283 {is_inferred="true"} ! negative regulation of sequestering of calcium ion
 is_a: GO:0051284 {is_inferred="true"} ! positive regulation of sequestering of calcium ion
 is_a: GO:0090281 {is_inferred="true"} ! negative regulation of calcium ion import
 is_a: GO:1903170 {is_inferred="true"} ! negative regulation of calcium ion transmembrane transport
@@ -45026,8 +45039,8 @@
 
 [Term]
 id: GO:0051918 ! negative regulation of fibrinolysis
+is_a: GO:0030195 {is_inferred="true"} ! negative regulation of blood coagulation
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
 is_a: GO:0051917 {is_inferred="true"} ! regulation of fibrinolysis
 
 [Term]
@@ -46513,8 +46526,8 @@
 
 [Term]
 id: GO:0060369 ! positive regulation of Fc receptor mediated stimulatory signaling pathway
-is_a: GO:0002684 {is_inferred="true"} ! positive regulation of immune system process
 is_a: GO:0009967 {is_inferred="true"} ! positive regulation of signal transduction
+is_a: GO:0050778 {is_inferred="true"} ! positive regulation of immune response
 is_a: GO:0060368 {is_inferred="true"} ! regulation of Fc receptor mediated stimulatory signaling pathway
 
 [Term]
@@ -46842,8 +46855,10 @@
 
 [Term]
 id: GO:0060520 ! activation of prostate induction by androgen receptor signaling pathway
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
+is_a: GO:0040019 {is_inferred="true"} ! positive regulation of embryonic development
 is_a: GO:0060685 {is_inferred="true"} ! regulation of prostatic bud formation
+is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
+is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
 
 [Term]
 id: GO:0060521 ! mesenchymal-epithelial cell signaling involved in prostate induction
@@ -47894,6 +47909,7 @@
 
 [Term]
 id: GO:0060965 ! negative regulation of gene silencing by miRNA
+is_a: GO:0017148 {is_inferred="true"} ! negative regulation of translation
 is_a: GO:0045727 {is_inferred="true"} ! positive regulation of translation
 is_a: GO:0060149 {is_inferred="true"} ! negative regulation of posttranscriptional gene silencing
 is_a: GO:0060964 {is_inferred="true"} ! regulation of gene silencing by miRNA
@@ -47915,6 +47931,7 @@
 
 [Term]
 id: GO:0060969 ! negative regulation of gene silencing
+is_a: GO:0010629 {is_inferred="true"} ! negative regulation of gene expression
 is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
 is_a: GO:0060968 {is_inferred="true"} ! regulation of gene silencing
 
@@ -50066,7 +50083,7 @@
 
 [Term]
 id: GO:0070426 ! positive regulation of nucleotide-binding oligomerization domain containing signaling pathway
-is_a: GO:0002684 {is_inferred="true"} ! positive regulation of immune system process
+is_a: GO:0045089 {is_inferred="true"} ! positive regulation of innate immune response
 is_a: GO:0070424 {is_inferred="true"} ! regulation of nucleotide-binding oligomerization domain containing signaling pathway
 is_a: GO:1902533 {is_inferred="true"} ! positive regulation of intracellular signal transduction
 
@@ -52553,11 +52570,11 @@
 
 [Term]
 id: GO:0071509 ! activation of MAPKK activity involved in conjugation with cellular fusion
-is_a: GO:0090028 {is_inferred="true"} ! positive regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
+is_a: GO:0071508 {is_inferred="true"} ! activation of MAPK activity involved in conjugation with cellular fusion
 
 [Term]
 id: GO:0071510 ! activation of MAPKKK activity involved in conjugation with cellular fusion
-is_a: GO:0090028 {is_inferred="true"} ! positive regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion
+is_a: GO:0071509 {is_inferred="true"} ! activation of MAPKK activity involved in conjugation with cellular fusion
 
 [Term]
 id: GO:0071511 ! inactivation of MAPK activity involved in conjugation with cellular fusion
@@ -62165,8 +62182,7 @@
 
 [Term]
 id: GO:1900237 ! positive regulation of induction of conjugation with cellular fusion
-is_a: GO:0031137 {is_inferred="true"} ! regulation of conjugation with cellular fusion
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
+is_a: GO:0031139 {is_inferred="true"} ! positive regulation of conjugation with cellular fusion
 
 [Term]
 id: GO:1900238 ! regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
@@ -62206,21 +62222,23 @@
 
 [Term]
 id: GO:1900245 ! positive regulation of MDA-5 signaling pathway
+is_a: GO:0001819 {is_inferred="true"} ! positive regulation of cytokine production
 is_a: GO:0002699 {is_inferred="true"} ! positive regulation of immune effector process
 is_a: GO:0002833 {is_inferred="true"} ! positive regulation of response to biotic stimulus
-is_a: GO:0031349 {is_inferred="true"} ! positive regulation of defense response
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
 is_a: GO:0039533 {is_inferred="true"} ! regulation of MDA-5 signaling pathway
+is_a: GO:0045089 {is_inferred="true"} ! positive regulation of innate immune response
 is_a: GO:0048524 {is_inferred="true"} ! positive regulation of viral process
 is_a: GO:1902533 {is_inferred="true"} ! positive regulation of intracellular signal transduction
 
 [Term]
 id: GO:1900246 ! positive regulation of RIG-I signaling pathway
+is_a: GO:0001819 {is_inferred="true"} ! positive regulation of cytokine production
 is_a: GO:0002699 {is_inferred="true"} ! positive regulation of immune effector process
 is_a: GO:0002833 {is_inferred="true"} ! positive regulation of response to biotic stimulus
-is_a: GO:0031349 {is_inferred="true"} ! positive regulation of defense response
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
 is_a: GO:0039535 {is_inferred="true"} ! regulation of RIG-I signaling pathway
+is_a: GO:0045089 {is_inferred="true"} ! positive regulation of innate immune response
 is_a: GO:0048524 {is_inferred="true"} ! positive regulation of viral process
 is_a: GO:1902533 {is_inferred="true"} ! positive regulation of intracellular signal transduction
 
@@ -62331,7 +62349,7 @@
 
 [Term]
 id: GO:1900273 ! positive regulation of long-term synaptic potentiation
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
+is_a: GO:0050806 {is_inferred="true"} ! positive regulation of synaptic transmission
 is_a: GO:1900271 {is_inferred="true"} ! regulation of long-term synaptic potentiation
 
 [Term]
@@ -62373,6 +62391,7 @@
 [Term]
 id: GO:1900281 ! positive regulation of CD4-positive, alpha-beta T cell costimulation
 is_a: GO:1900279 {is_inferred="true"} ! regulation of CD4-positive, alpha-beta T cell costimulation
+is_a: GO:2000516 {is_inferred="true"} ! positive regulation of CD4-positive, alpha-beta T cell activation
 is_a: GO:2000525 {is_inferred="true"} ! positive regulation of T cell costimulation
 
 [Term]
@@ -63016,7 +63035,7 @@
 
 [Term]
 id: GO:1900404 ! positive regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter
-is_a: GO:0006282 {is_inferred="true"} ! regulation of DNA repair
+is_a: GO:0045739 {is_inferred="true"} ! positive regulation of DNA repair
 is_a: GO:0045944 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter
 
 [Term]
@@ -63063,6 +63082,7 @@
 
 [Term]
 id: GO:1900417 ! negative regulation of transmembrane transport by negative regulation of transcription from RNA polymerase II promoter
+is_a: GO:0034763 {is_inferred="true"} ! negative regulation of transmembrane transport
 is_a: GO:0034764 {is_inferred="true"} ! positive regulation of transmembrane transport
 is_a: GO:1900392 {is_inferred="true"} ! regulation of transport by negative regulation of transcription from RNA polymerase II promoter
 
@@ -63088,12 +63108,12 @@
 [Term]
 id: GO:1900422 ! positive regulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter
 is_a: GO:0045944 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter
-is_a: GO:1900419 {is_inferred="true"} ! regulation of cellular alcohol catabolic process
+is_a: GO:1900421 {is_inferred="true"} ! positive regulation of cellular alcohol catabolic process
 
 [Term]
 id: GO:1900423 ! positive regulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter
-is_a: GO:0031494 {is_inferred="true"} ! regulation of mating type switching
 is_a: GO:0045944 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter
+is_a: GO:1900374 {is_inferred="true"} ! positive regulation of mating type switching by regulation of transcription from RNA polymerase II promoter
 
 [Term]
 id: GO:1900424 ! regulation of defense response to bacterium
@@ -63254,7 +63274,7 @@
 
 [Term]
 id: GO:1900453 ! negative regulation of long term synaptic depression
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
+is_a: GO:0050805 {is_inferred="true"} ! negative regulation of synaptic transmission
 is_a: GO:0050806 {is_inferred="true"} ! positive regulation of synaptic transmission
 is_a: GO:1900452 {is_inferred="true"} ! regulation of long term synaptic depression
 
@@ -63311,7 +63331,7 @@
 is_a: GO:0033243 {is_inferred="true"} ! positive regulation of cellular amine catabolic process
 is_a: GO:0045764 {is_inferred="true"} ! positive regulation of cellular amino acid metabolic process
 is_a: GO:0072365 {is_inferred="true"} ! regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter
-is_a: GO:1900081 {is_inferred="true"} ! regulation of arginine catabolic process
+is_a: GO:1900082 {is_inferred="true"} ! negative regulation of arginine catabolic process
 
 [Term]
 id: GO:1900466 ! positive regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter
@@ -63646,6 +63666,7 @@
 [Term]
 id: GO:1900526 ! negative regulation of phosphatidylserine biosynthetic process by negative regulation of transcription from RNA polymerase II promoter
 is_a: GO:0000122 {is_inferred="true"} ! negative regulation of transcription from RNA polymerase II promoter
+is_a: GO:1900469 {is_inferred="true"} ! negative regulation of phosphatidylserine biosynthetic process
 is_a: GO:1900470 {is_inferred="true"} ! positive regulation of phosphatidylserine biosynthetic process
 
 [Term]
@@ -67868,6 +67889,7 @@
 [Term]
 id: GO:1901321 ! positive regulation of heart induction
 is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
+is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:0090381 {is_inferred="true"} ! regulation of heart induction
 
 [Term]
@@ -71160,8 +71182,8 @@
 
 [Term]
 id: GO:1901977 ! negative regulation of cell cycle checkpoint
+is_a: GO:0045786 {is_inferred="true"} ! negative regulation of cell cycle
 is_a: GO:0045787 {is_inferred="true"} ! positive regulation of cell cycle
-is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
 is_a: GO:1901976 {is_inferred="true"} ! regulation of cell cycle checkpoint
 
 [Term]
@@ -73116,6 +73138,7 @@
 [Term]
 id: GO:1902373 ! negative regulation of mRNA catabolic process
 is_a: GO:0010628 {is_inferred="true"} ! positive regulation of gene expression
+is_a: GO:0010629 {is_inferred="true"} ! negative regulation of gene expression
 is_a: GO:0061013 {is_inferred="true"} ! regulation of mRNA catabolic process
 is_a: GO:1902369 {is_inferred="true"} ! negative regulation of RNA catabolic process
 is_a: GO:1903312 {is_inferred="true"} ! negative regulation of mRNA metabolic process
@@ -73366,9 +73389,8 @@
 
 [Term]
 id: GO:1902426 ! deactivation of mitotic spindle assembly checkpoint
-is_a: GO:0010948 {is_inferred="true"} ! negative regulation of cell cycle process
+is_a: GO:0045841 {is_inferred="true"} ! negative regulation of mitotic metaphase/anaphase transition
 is_a: GO:0045842 {is_inferred="true"} ! positive regulation of mitotic metaphase/anaphase transition
-is_a: GO:0045930 {is_inferred="true"} ! negative regulation of mitotic cell cycle
 is_a: GO:0090233 {is_inferred="true"} ! negative regulation of spindle checkpoint
 is_a: GO:0090266 {is_inferred="true"} ! regulation of mitotic cell cycle spindle assembly checkpoint
 
@@ -73687,6 +73709,7 @@
 [Term]
 id: GO:1902505 ! negative regulation of signal transduction involved in mitotic G2 DNA damage checkpoint
 is_a: GO:0010971 {is_inferred="true"} ! positive regulation of G2/M transition of mitotic cell cycle
+is_a: GO:0010972 {is_inferred="true"} ! negative regulation of G2/M transition of mitotic cell cycle
 is_a: GO:1902504 {is_inferred="true"} ! regulation of signal transduction involved in mitotic G2 DNA damage checkpoint
 is_a: GO:1902532 {is_inferred="true"} ! negative regulation of intracellular signal transduction
 is_a: GO:1904290 {is_inferred="true"} ! negative regulation of mitotic DNA damage checkpoint
@@ -75448,6 +75471,7 @@
 [Term]
 id: GO:1902879 ! negative regulation of BMP signaling pathway involved in spinal cord association neuron specification
 is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
+is_a: GO:0021914 {is_inferred="true"} ! negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
 is_a: GO:0030514 {is_inferred="true"} ! negative regulation of BMP signaling pathway
 is_a: GO:0045880 {is_inferred="true"} ! positive regulation of smoothened signaling pathway
 is_a: GO:0051962 {is_inferred="true"} ! positive regulation of nervous system development
@@ -75489,7 +75513,7 @@
 [Term]
 id: GO:1902887 ! positive regulation of proteasome-activating ATPase activity
 is_a: GO:0032781 {is_inferred="true"} ! positive regulation of ATPase activity
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
+is_a: GO:1901800 {is_inferred="true"} ! positive regulation of proteasomal protein catabolic process
 is_a: GO:1902885 {is_inferred="true"} ! regulation of proteasome-activating ATPase activity
 
 [Term]
@@ -77108,9 +77132,9 @@
 
 [Term]
 id: GO:1903247 ! positive regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate
+is_a: GO:0045823 {is_inferred="true"} ! positive regulation of heart contraction
 is_a: GO:1901206 {is_inferred="true"} ! positive regulation of adrenergic receptor signaling pathway involved in heart process
 is_a: GO:1903245 {is_inferred="true"} ! regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate
-is_a: GO:1903524 {is_inferred="true"} ! positive regulation of blood circulation
 
 [Term]
 id: GO:1903248 ! regulation of citrulline biosynthetic process
@@ -79309,7 +79333,6 @@
 
 [Term]
 id: GO:1903704 ! negative regulation of production of siRNA involved in RNA interference
-is_a: GO:0010629 {is_inferred="true"} ! negative regulation of gene expression
 is_a: GO:0048585 {is_inferred="true"} ! negative regulation of response to stimulus
 is_a: GO:0051253 {is_inferred="true"} ! negative regulation of RNA metabolic process
 is_a: GO:0090065 {is_inferred="true"} ! regulation of production of siRNA involved in RNA interference
@@ -79738,7 +79761,6 @@
 
 [Term]
 id: GO:1903799 ! negative regulation of production of miRNAs involved in gene silencing by miRNA
-is_a: GO:0010629 {is_inferred="true"} ! negative regulation of gene expression
 is_a: GO:0048585 {is_inferred="true"} ! negative regulation of response to stimulus
 is_a: GO:0051253 {is_inferred="true"} ! negative regulation of RNA metabolic process
 is_a: GO:0060965 {is_inferred="true"} ! negative regulation of gene silencing by miRNA
@@ -80697,7 +80719,7 @@
 [Term]
 id: GO:1904001 ! positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter
 is_a: GO:0045944 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter
-is_a: GO:1903930 {is_inferred="true"} ! regulation of pyrimidine-containing compound salvage
+is_a: GO:1903931 {is_inferred="true"} ! positive regulation of pyrimidine-containing compound salvage
 
 [Term]
 id: GO:1904002 ! regulation of sebum secreting cell proliferation
@@ -80785,6 +80807,7 @@
 [Term]
 id: GO:1904021 ! negative regulation of G-protein coupled receptor internalization
 is_a: GO:0002091 {is_inferred="true"} ! negative regulation of receptor internalization
+is_a: GO:0045744 {is_inferred="true"} ! negative regulation of G-protein coupled receptor protein signaling pathway
 is_a: GO:0045745 {is_inferred="true"} ! positive regulation of G-protein coupled receptor protein signaling pathway
 is_a: GO:1904020 {is_inferred="true"} ! regulation of G-protein coupled receptor internalization
 
@@ -82250,6 +82273,7 @@
 [Term]
 id: GO:1904324 ! negative regulation of inhibitory G-protein coupled receptor phosphorylation
 is_a: GO:0001933 {is_inferred="true"} ! negative regulation of protein phosphorylation
+is_a: GO:0045744 {is_inferred="true"} ! negative regulation of G-protein coupled receptor protein signaling pathway
 is_a: GO:0045745 {is_inferred="true"} ! positive regulation of G-protein coupled receptor protein signaling pathway
 is_a: GO:1904323 {is_inferred="true"} ! regulation of inhibitory G-protein coupled receptor phosphorylation
 
@@ -83129,6 +83153,7 @@
 
 [Term]
 id: GO:1904501 ! positive regulation of chromatin-mediated maintenance of transcription
+is_a: GO:0045893 {is_inferred="true"} ! positive regulation of transcription, DNA-templated
 is_a: GO:1904499 {is_inferred="true"} ! regulation of chromatin-mediated maintenance of transcription
 is_a: GO:1905269 {is_inferred="true"} ! positive regulation of chromatin organization
 
@@ -86014,8 +86039,8 @@
 
 [Term]
 id: GO:1905091 ! positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
-is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
 is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
+is_a: GO:1901526 {is_inferred="true"} ! positive regulation of macromitophagy
 is_a: GO:1905089 {is_inferred="true"} ! regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
 
 [Term]
@@ -86053,14 +86078,14 @@
 
 [Term]
 id: GO:1905098 ! negative regulation of guanyl-nucleotide exchange factor activity
-is_a: GO:0044092 {is_inferred="true"} ! negative regulation of molecular function
 is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
 is_a: GO:0051099 {is_inferred="true"} ! positive regulation of binding
+is_a: GO:0051100 {is_inferred="true"} ! negative regulation of binding
 is_a: GO:1905097 {is_inferred="true"} ! regulation of guanyl-nucleotide exchange factor activity
 
 [Term]
 id: GO:1905099 ! positive regulation of guanyl-nucleotide exchange factor activity
-is_a: GO:0044093 {is_inferred="true"} ! positive regulation of molecular function
+is_a: GO:0043547 {is_inferred="true"} ! positive regulation of GTPase activity
 is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
 is_a: GO:1905097 {is_inferred="true"} ! regulation of guanyl-nucleotide exchange factor activity
 
@@ -87065,6 +87090,7 @@
 
 [Term]
 id: GO:1905309 ! positive regulation of cohesin loading
+is_a: GO:0043388 {is_inferred="true"} ! positive regulation of DNA binding
 is_a: GO:0045876 {is_inferred="true"} ! positive regulation of sister chromatid cohesion
 is_a: GO:0071922 {is_inferred="true"} ! regulation of cohesin loading
 is_a: GO:1903829 {is_inferred="true"} ! positive regulation of cellular protein localization
@@ -87195,8 +87221,9 @@
 [Term]
 id: GO:1905338 ! negative regulation of cohesin unloading
 is_a: GO:0043388 {is_inferred="true"} ! positive regulation of DNA binding
+is_a: GO:0043392 {is_inferred="true"} ! negative regulation of DNA binding
+is_a: GO:0045875 {is_inferred="true"} ! negative regulation of sister chromatid cohesion
 is_a: GO:0045876 {is_inferred="true"} ! positive regulation of sister chromatid cohesion
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
 is_a: GO:1905343 {is_inferred="true"} ! regulation of cohesin unloading
 
 [Term]
@@ -93780,7 +93807,7 @@
 
 [Term]
 id: GO:2000525 ! positive regulation of T cell costimulation
-is_a: GO:0002684 {is_inferred="true"} ! positive regulation of immune system process
+is_a: GO:0050870 {is_inferred="true"} ! positive regulation of T cell activation
 is_a: GO:2000523 {is_inferred="true"} ! regulation of T cell costimulation
 
 [Term]
@@ -94311,6 +94338,7 @@
 [Term]
 id: GO:2000640 ! positive regulation of SREBP signaling pathway
 is_a: GO:0009967 {is_inferred="true"} ! positive regulation of signal transduction
+is_a: GO:0045944 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter
 is_a: GO:2000638 {is_inferred="true"} ! regulation of SREBP signaling pathway
 
 [Term]
@@ -95197,9 +95225,10 @@
 
 [Term]
 id: GO:2000813 ! negative regulation of barbed-end actin filament capping
+is_a: GO:0030835 {is_inferred="true"} ! negative regulation of actin filament depolymerization
 is_a: GO:0030836 {is_inferred="true"} ! positive regulation of actin filament depolymerization
+is_a: GO:0030837 {is_inferred="true"} ! negative regulation of actin filament polymerization
 is_a: GO:0030838 {is_inferred="true"} ! positive regulation of actin filament polymerization
-is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:2000812 {is_inferred="true"} ! regulation of barbed-end actin filament capping
 
 [Term]
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 39852)
+++ go_inferences.obo	(working copy)
@@ -1747,7 +1747,7 @@
 
 [Term]
 id: GO:0001931 ! uropod
-is_a: GO:0042995 {is_inferred="true"} ! cell projection
+is_a: GO:0120025 {is_inferred="true"} ! plasma membrane bounded cell projection
 
 [Term]
 id: GO:0001932 ! regulation of protein phosphorylation
@@ -29292,6 +29292,10 @@
 is_a: GO:1903008 {is_inferred="true"} ! organelle disassembly
 
 [Term]
+id: GO:0035618 ! root hair
+is_a: GO:0120025 {is_inferred="true"} ! plasma membrane bounded cell projection
+
+[Term]
 id: GO:0035622 ! intrahepatic bile duct development
 is_a: GO:0061009 {is_inferred="true"} ! common bile duct development
 
@@ -30058,6 +30062,10 @@
 is_a: GO:1901663 {is_inferred="true"} ! quinone biosynthetic process
 
 [Term]
+id: GO:0036194 ! muscle cell projection
+is_a: GO:0120025 {is_inferred="true"} ! plasma membrane bounded cell projection
+
+[Term]
 id: GO:0036196 ! zymosterol metabolic process
 is_a: GO:0016125 {is_inferred="true"} ! sterol metabolic process
 is_a: GO:1902652 {is_inferred="true"} ! secondary alcohol metabolic process
@@ -57358,6 +57366,10 @@
 is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
 
 [Term]
+id: GO:0090406 ! pollen tube
+is_a: GO:0120025 {is_inferred="true"} ! plasma membrane bounded cell projection
+
+[Term]
 id: GO:0090407 ! organophosphate biosynthetic process
 is_a: GO:0019637 {is_inferred="true"} ! organophosphate metabolic process
 is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
@@ -58169,6 +58181,10 @@
 is_a: GO:0042493 {is_inferred="true"} ! response to drug
 
 [Term]
+id: GO:0097386 ! glial cell projection
+is_a: GO:0120025 {is_inferred="true"} ! plasma membrane bounded cell projection
+
+[Term]
 id: GO:0097403 ! cellular response to raffinose
 is_a: GO:0071322 {is_inferred="true"} ! cellular response to carbohydrate stimulus
 is_a: GO:1901545 {is_inferred="true"} ! response to raffinose
@@ -58253,6 +58269,10 @@
 is_a: GO:1903441 {is_inferred="true"} ! protein localization to ciliary membrane
 
 [Term]
+id: GO:0097511 ! dendritic cell dendrite
+is_a: GO:0120025 {is_inferred="true"} ! plasma membrane bounded cell projection
+
+[Term]
 id: GO:0097516 ! microvillar actin bundle
 is_a: GO:0098859 {is_inferred="true"} ! actin filament bundle of actin-based cell projection
 
@@ -61003,6 +61023,10 @@
 is_a: GO:0017046 {is_inferred="true"} ! peptide hormone binding
 
 [Term]
+id: GO:0120025 ! plasma membrane bounded cell projection
+is_a: GO:0042995 {is_inferred="true"} ! cell projection
+
+[Term]
 id: GO:0140009 ! L-aspartate import across plasma membrane
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 is_a: GO:0089712 {is_inferred="true"} ! L-aspartate transmembrane transport
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 39811)
+++ go_inferences.obo	(working copy)
@@ -76911,6 +76911,7 @@
 [Term]
 id: GO:1903211 ! mitotic recombination involved in replication fork processing
 is_a: GO:0006312 {is_inferred="true"} ! mitotic recombination
+is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
 id: GO:1903212 ! protein localization to mating-type region heterochromatin
@@ -76962,7 +76963,7 @@
 [Term]
 id: GO:1903221 ! regulation of mitotic recombination involved in replication fork processing
 is_a: GO:0000019 {is_inferred="true"} ! regulation of mitotic recombination
-is_a: GO:0090329 {is_inferred="true"} ! regulation of DNA-dependent DNA replication
+is_a: GO:1903463 {is_inferred="true"} ! regulation of mitotic cell cycle DNA replication
 
 [Term]
 id: GO:1903222 ! quinolinic acid transmembrane transport
@@ -90645,6 +90646,10 @@
 is_a: GO:0044432 {is_inferred="true"} ! endoplasmic reticulum part
 
 [Term]
+id: GO:1990426 ! mitotic recombination-dependent replication fork processing
+is_a: GO:1990505 {is_inferred="true"} ! mitotic DNA replication maintenance of fidelity
+
+[Term]
 id: GO:1990427 ! stereocilia tip-link density
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
 
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 39688)
+++ go_inferences.obo	(working copy)
@@ -43957,6 +43957,10 @@
 is_a: GO:0051421 {is_inferred="true"} ! regulation of endo-1,4-beta-xylanase activity
 
 [Term]
+id: GO:0051424 ! corticotropin-releasing hormone binding
+is_a: GO:0017046 {is_inferred="true"} ! peptide hormone binding
+
+[Term]
 id: GO:0051436 ! negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
 is_a: GO:0051439 {is_inferred="true"} ! regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
 
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 39687)
+++ go_inferences.obo	(working copy)
@@ -60991,6 +60991,14 @@
 is_a: GO:0120015 {is_inferred="true"} ! intermembrane sterol transfer activity
 
 [Term]
+id: GO:0120022 ! glucagon binding
+is_a: GO:0017046 {is_inferred="true"} ! peptide hormone binding
+
+[Term]
+id: GO:0120023 ! somatostatin binding
+is_a: GO:0017046 {is_inferred="true"} ! peptide hormone binding
+
+[Term]
 id: GO:0140009 ! L-aspartate import across plasma membrane
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 is_a: GO:0089712 {is_inferred="true"} ! L-aspartate transmembrane transport
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 39686)
+++ go_inferences.obo	(working copy)
@@ -60938,6 +60938,59 @@
 is_a: GO:0120006 {is_inferred="true"} ! regulation of glutamatergic neuron differentiation
 
 [Term]
+id: GO:0120010 ! intermembrane phospholipid transfer
+is_a: GO:0015914 {is_inferred="true"} ! phospholipid transport
+is_a: GO:0120009 {is_inferred="true"} ! intermembrane lipid transfer
+
+[Term]
+id: GO:0120011 ! intermembrane sterol transfer
+is_a: GO:0015918 {is_inferred="true"} ! sterol transport
+is_a: GO:0120009 {is_inferred="true"} ! intermembrane lipid transfer
+
+[Term]
+id: GO:0120012 ! intermembrane sphingolipid transfer
+is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
+is_a: GO:0120009 {is_inferred="true"} ! intermembrane lipid transfer
+
+[Term]
+id: GO:0120014 ! intermembrane phospholipid transfer activity
+is_a: GO:0005548 {is_inferred="true"} ! phospholipid transporter activity
+is_a: GO:0120013 {is_inferred="true"} ! intermembrane lipid transfer activity
+
+[Term]
+id: GO:0120015 ! intermembrane sterol transfer activity
+is_a: GO:0015248 {is_inferred="true"} ! sterol transporter activity
+
+[Term]
+id: GO:0120016 ! intermembrane sphingolipid transfer activity
+is_a: GO:0046624 {is_inferred="true"} ! sphingolipid transporter activity
+is_a: GO:0120013 {is_inferred="true"} ! intermembrane lipid transfer activity
+
+[Term]
+id: GO:0120017 ! intermembrane ceramide transfer activity
+is_a: GO:0035620 {is_inferred="true"} ! ceramide transporter activity
+is_a: GO:0120016 {is_inferred="true"} ! intermembrane sphingolipid transfer activity
+
+[Term]
+id: GO:0120018 ! intermembrane phosphotidylinositol transfer activity
+is_a: GO:0008526 {is_inferred="true"} ! phosphatidylinositol transporter activity
+is_a: GO:0120014 {is_inferred="true"} ! intermembrane phospholipid transfer activity
+
+[Term]
+id: GO:0120019 ! intermembrane phosphotidylcholine transfer activity
+is_a: GO:0008525 {is_inferred="true"} ! phosphatidylcholine transporter activity
+is_a: GO:0120014 {is_inferred="true"} ! intermembrane phospholipid transfer activity
+
+[Term]
+id: GO:0120020 ! intermembrane cholesterol transfer activity
+is_a: GO:0017127 {is_inferred="true"} ! cholesterol transporter activity
+is_a: GO:0120015 {is_inferred="true"} ! intermembrane sterol transfer activity
+
+[Term]
+id: GO:0120021 ! intermembrane oxysterol transfer activity
+is_a: GO:0120015 {is_inferred="true"} ! intermembrane sterol transfer activity
+
+[Term]
 id: GO:0140009 ! L-aspartate import across plasma membrane
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 is_a: GO:0089712 {is_inferred="true"} ! L-aspartate transmembrane transport
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 39529)
+++ go_inferences.obo	(working copy)
@@ -60920,6 +60920,10 @@
 is_a: GO:0044707 {is_inferred="true"} ! single-multicellular organism process
 
 [Term]
+id: GO:0106002 ! mCRD-mediated mRNA stability complex
+is_a: GO:0044445 {is_inferred="true"} ! cytosolic part
+
+[Term]
 id: GO:0120006 ! regulation of glutamatergic neuron differentiation
 is_a: GO:0045664 {is_inferred="true"} ! regulation of neuron differentiation
 
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

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changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 39526)
+++ go_inferences.obo	(working copy)
@@ -1794,10 +1794,6 @@
 is_a: GO:0097367 {is_inferred="true"} ! carbohydrate derivative binding
 
 [Term]
-id: GO:0001951 ! intestinal D-glucose absorption
-is_a: GO:0044707 {is_inferred="true"} ! single-multicellular organism process
-
-[Term]
 id: GO:0001952 ! regulation of cell-matrix adhesion
 is_a: GO:0010810 {is_inferred="true"} ! regulation of cell-substrate adhesion
 
@@ -12221,6 +12217,10 @@
 is_a: GO:0010665 {is_inferred="true"} ! regulation of cardiac muscle cell apoptotic process
 
 [Term]
+id: GO:0010674 ! negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle
+is_a: GO:0051038 {is_inferred="true"} ! negative regulation of transcription involved in meiotic cell cycle
+
+[Term]
 id: GO:0010678 ! negative regulation of cellular carbohydrate metabolic process by negative regulation of transcription, DNA-templated
 is_a: GO:0010677 {is_inferred="true"} ! negative regulation of cellular carbohydrate metabolic process
 is_a: GO:0045892 {is_inferred="true"} ! negative regulation of transcription, DNA-templated
@@ -48786,6 +48786,7 @@
 
 [Term]
 id: GO:0061454 ! Golgi calcium ion export
+is_a: GO:0061856 {is_inferred="true"} ! Golgi calcium ion transmembrane transport
 is_a: GO:1901660 {is_inferred="true"} ! calcium ion export
 
 [Term]
@@ -49243,6 +49244,11 @@
 is_a: GO:0061853 {is_inferred="true"} ! regulation of neuroblast migration
 
 [Term]
+id: GO:0061856 ! Golgi calcium ion transmembrane transport
+is_a: GO:0032472 {is_inferred="true"} ! Golgi calcium ion transport
+is_a: GO:0070588 {is_inferred="true"} ! calcium ion transmembrane transport
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
@@ -60910,6 +60916,10 @@
 is_a: GO:0050828 {is_inferred="true"} ! regulation of liquid surface tension
 
 [Term]
+id: GO:0106001 ! intestinal hexose absorption
+is_a: GO:0044707 {is_inferred="true"} ! single-multicellular organism process
+
+[Term]
 id: GO:0120006 ! regulation of glutamatergic neuron differentiation
 is_a: GO:0045664 {is_inferred="true"} ! regulation of neuron differentiation
 
@@ -60924,6 +60934,15 @@
 is_a: GO:0120006 {is_inferred="true"} ! regulation of glutamatergic neuron differentiation
 
 [Term]
+id: GO:0140009 ! L-aspartate import across plasma membrane
+is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
+is_a: GO:0089712 {is_inferred="true"} ! L-aspartate transmembrane transport
+
+[Term]
+id: GO:0140010 ! D-aspartate transmembrane transporter activity
+is_a: GO:0015556 {is_inferred="true"} ! C4-dicarboxylate transmembrane transporter activity
+
+[Term]
 id: GO:1900000 ! regulation of anthocyanin catabolic process
 is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
 is_a: GO:0031537 {is_inferred="true"} ! regulation of anthocyanin metabolic process
@@ -62893,11 +62912,6 @@
 is_a: GO:1900393 {is_inferred="true"} ! regulation of iron ion transport by regulation of transcription from RNA polymerase II promoter
 
 [Term]
-id: GO:1900401 ! regulation of meiosis by regulation of transcription from RNA polymerase II promoter
-is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
-is_a: GO:0040020 {is_inferred="true"} ! regulation of meiotic nuclear division
-
-[Term]
 id: GO:1900402 ! regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter
 is_a: GO:0006109 {is_inferred="true"} ! regulation of carbohydrate metabolic process
 is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
@@ -63251,16 +63265,6 @@
 is_a: GO:0031495 {is_inferred="true"} ! negative regulation of mating type switching
 
 [Term]
-id: GO:1900475 ! positive regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter
-is_a: GO:0000122 {is_inferred="true"} ! negative regulation of transcription from RNA polymerase II promoter
-is_a: GO:1900401 {is_inferred="true"} ! regulation of meiosis by regulation of transcription from RNA polymerase II promoter
-
-[Term]
-id: GO:1900476 ! positive regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter
-is_a: GO:0045944 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter
-is_a: GO:1900401 {is_inferred="true"} ! regulation of meiosis by regulation of transcription from RNA polymerase II promoter
-
-[Term]
 id: GO:1900477 ! negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter
 is_a: GO:0000122 {is_inferred="true"} ! negative regulation of transcription from RNA polymerase II promoter
 is_a: GO:2000134 {is_inferred="true"} ! negative regulation of G1/S transition of mitotic cell cycle
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 39341)
+++ go_inferences.obo	(working copy)
@@ -49229,6 +49229,20 @@
 is_a: GO:0044463 {is_inferred="true"} ! cell projection part
 
 [Term]
+id: GO:0061853 ! regulation of neuroblast migration
+is_a: GO:0030334 {is_inferred="true"} ! regulation of cell migration
+
+[Term]
+id: GO:0061854 ! positive regulation of neuroblast migration
+is_a: GO:0030335 {is_inferred="true"} ! positive regulation of cell migration
+is_a: GO:0061853 {is_inferred="true"} ! regulation of neuroblast migration
+
+[Term]
+id: GO:0061855 ! negative regulation of neuroblast migration
+is_a: GO:0030336 {is_inferred="true"} ! negative regulation of cell migration
+is_a: GO:0061853 {is_inferred="true"} ! regulation of neuroblast migration
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 39337)
+++ go_inferences.obo	(working copy)
@@ -14555,6 +14555,10 @@
 is_a: GO:0043225 {is_inferred="true"} ! ATPase-coupled anion transmembrane transporter activity
 
 [Term]
+id: GO:0015440 ! peptide-transporting ATPase activity
+is_a: GO:1904680 {is_inferred="true"} ! peptide transmembrane transporter activity
+
+[Term]
 id: GO:0015444 ! magnesium-importing ATPase activity
 is_a: GO:0019829 {is_inferred="true"} ! cation-transporting ATPase activity
 
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synced

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synced

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synced

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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 39197)
+++ go_inferences.obo	(working copy)
@@ -77944,10 +77944,6 @@
 is_a: GO:0090335 {is_inferred="true"} ! regulation of brown fat cell differentiation
 
 [Term]
-id: GO:1903445 ! protein transport from ciliary membrane to plasma membrane
-is_a: GO:0032594 {is_inferred="true"} ! protein transport within lipid bilayer
-
-[Term]
 id: GO:1903446 ! geraniol metabolic process
 is_a: GO:0016093 {is_inferred="true"} ! polyprenol metabolic process
 is_a: GO:0016098 {is_inferred="true"} ! monoterpenoid metabolic process
------------------------------------------------------------------------
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synced

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 39125)
+++ go_inferences.obo	(working copy)
@@ -60892,6 +60892,20 @@
 is_a: GO:0050828 {is_inferred="true"} ! regulation of liquid surface tension
 
 [Term]
+id: GO:0120006 ! regulation of glutamatergic neuron differentiation
+is_a: GO:0045664 {is_inferred="true"} ! regulation of neuron differentiation
+
+[Term]
+id: GO:0120007 ! negative regulation of glutamatergic neuron differentiation
+is_a: GO:0045665 {is_inferred="true"} ! negative regulation of neuron differentiation
+is_a: GO:0120006 {is_inferred="true"} ! regulation of glutamatergic neuron differentiation
+
+[Term]
+id: GO:0120008 ! positive  regulation of glutamatergic neuron differentiation
+is_a: GO:0045666 {is_inferred="true"} ! positive regulation of neuron differentiation
+is_a: GO:0120006 {is_inferred="true"} ! regulation of glutamatergic neuron differentiation
+
+[Term]
 id: GO:1900000 ! regulation of anthocyanin catabolic process
 is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
 is_a: GO:0031537 {is_inferred="true"} ! regulation of anthocyanin metabolic process
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

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changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 39119)
+++ go_inferences.obo	(working copy)
@@ -22281,20 +22281,20 @@
 is_a: GO:0099531 {is_inferred="true"} ! presynaptic process involved in chemical synaptic transmission
 
 [Term]
-id: GO:0031630 ! regulation of synaptic vesicle fusion to presynaptic membrane
+id: GO:0031630 ! regulation of synaptic vesicle fusion to presynaptic active zone membrane
 is_a: GO:0031338 {is_inferred="true"} ! regulation of vesicle fusion
 is_a: GO:2000300 {is_inferred="true"} ! regulation of synaptic vesicle exocytosis
 
 [Term]
-id: GO:0031631 ! negative regulation of synaptic vesicle fusion to presynaptic membrane
+id: GO:0031631 ! negative regulation of synaptic vesicle fusion to presynaptic active zone membrane
 is_a: GO:0031339 {is_inferred="true"} ! negative regulation of vesicle fusion
-is_a: GO:0031630 {is_inferred="true"} ! regulation of synaptic vesicle fusion to presynaptic membrane
+is_a: GO:0031630 {is_inferred="true"} ! regulation of synaptic vesicle fusion to presynaptic active zone membrane
 is_a: GO:2000301 {is_inferred="true"} ! negative regulation of synaptic vesicle exocytosis
 
 [Term]
-id: GO:0031632 ! positive regulation of synaptic vesicle fusion to presynaptic membrane
+id: GO:0031632 ! positive regulation of synaptic vesicle fusion to presynaptic active zone membrane
 is_a: GO:0031340 {is_inferred="true"} ! positive regulation of vesicle fusion
-is_a: GO:0031630 {is_inferred="true"} ! regulation of synaptic vesicle fusion to presynaptic membrane
+is_a: GO:0031630 {is_inferred="true"} ! regulation of synaptic vesicle fusion to presynaptic active zone membrane
 is_a: GO:2000302 {is_inferred="true"} ! positive regulation of synaptic vesicle exocytosis
 
 [Term]
@@ -60175,7 +60175,7 @@
 
 [Term]
 id: GO:0099502 ! calcium-dependent activation of synaptic vesicle fusion
-is_a: GO:0031632 {is_inferred="true"} ! positive regulation of synaptic vesicle fusion to presynaptic membrane
+is_a: GO:0031632 {is_inferred="true"} ! positive regulation of synaptic vesicle fusion to presynaptic active zone membrane
 is_a: GO:0099531 {is_inferred="true"} ! presynaptic process involved in chemical synaptic transmission
 
 [Term]
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

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r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 39116)
+++ go_inferences.obo	(working copy)
@@ -7220,7 +7220,6 @@
 [Term]
 id: GO:0006691 ! leukotriene metabolic process
 is_a: GO:0006690 {is_inferred="true"} ! icosanoid metabolic process
-is_a: GO:0033559 {is_inferred="true"} ! unsaturated fatty acid metabolic process
 
 [Term]
 id: GO:0006692 ! prostanoid metabolic process
@@ -17915,7 +17914,6 @@
 
 [Term]
 id: GO:0019370 ! leukotriene biosynthetic process
-is_a: GO:0006636 {is_inferred="true"} ! unsaturated fatty acid biosynthetic process
 is_a: GO:0006691 {is_inferred="true"} ! leukotriene metabolic process
 is_a: GO:0046456 {is_inferred="true"} ! icosanoid biosynthetic process
 
@@ -28236,6 +28234,7 @@
 [Term]
 id: GO:0034695 ! response to prostaglandin E
 is_a: GO:0034694 {is_inferred="true"} ! response to prostaglandin
+is_a: GO:0097305 {is_inferred="true"} ! response to alcohol
 is_a: GO:1901654 {is_inferred="true"} ! response to ketone
 
 [Term]
@@ -29932,7 +29931,6 @@
 [Term]
 id: GO:0036100 ! leukotriene catabolic process
 is_a: GO:0006691 {is_inferred="true"} ! leukotriene metabolic process
-is_a: GO:0009062 {is_inferred="true"} ! fatty acid catabolic process
 is_a: GO:1901523 {is_inferred="true"} ! icosanoid catabolic process
 
 [Term]
@@ -29946,6 +29944,7 @@
 id: GO:0036102 ! leukotriene B4 metabolic process
 is_a: GO:0001676 {is_inferred="true"} ! long-chain fatty acid metabolic process
 is_a: GO:0006691 {is_inferred="true"} ! leukotriene metabolic process
+is_a: GO:0033559 {is_inferred="true"} ! unsaturated fatty acid metabolic process
 is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
 
 [Term]
@@ -52186,6 +52185,7 @@
 
 [Term]
 id: GO:0071380 ! cellular response to prostaglandin E stimulus
+is_a: GO:0097306 {is_inferred="true"} ! cellular response to alcohol
 is_a: GO:1901655 {is_inferred="true"} ! cellular response to ketone
 
 [Term]
@@ -52931,7 +52931,6 @@
 
 [Term]
 id: GO:0071716 ! leukotriene transport
-is_a: GO:0015908 {is_inferred="true"} ! fatty acid transport
 is_a: GO:0071715 {is_inferred="true"} ! icosanoid transport
 
 [Term]
@@ -57944,6 +57943,7 @@
 
 [Term]
 id: GO:0097251 ! leukotriene B4 biosynthetic process
+is_a: GO:0006636 {is_inferred="true"} ! unsaturated fatty acid biosynthetic process
 is_a: GO:0019370 {is_inferred="true"} ! leukotriene biosynthetic process
 is_a: GO:0036102 {is_inferred="true"} ! leukotriene B4 metabolic process
 is_a: GO:0042759 {is_inferred="true"} ! long-chain fatty acid biosynthetic process
@@ -69808,6 +69808,7 @@
 
 [Term]
 id: GO:1901748 ! leukotriene D4 metabolic process
+is_a: GO:0006518 {is_inferred="true"} ! peptide metabolic process
 is_a: GO:0006691 {is_inferred="true"} ! leukotriene metabolic process
 is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
 
@@ -69814,6 +69815,7 @@
 [Term]
 id: GO:1901749 ! leukotriene D4 catabolic process
 is_a: GO:0036100 {is_inferred="true"} ! leukotriene catabolic process
+is_a: GO:0043171 {is_inferred="true"} ! peptide catabolic process
 is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
 is_a: GO:1901748 {is_inferred="true"} ! leukotriene D4 metabolic process
 
@@ -69820,6 +69822,7 @@
 [Term]
 id: GO:1901750 ! leukotriene D4 biosynthetic process
 is_a: GO:0019370 {is_inferred="true"} ! leukotriene biosynthetic process
+is_a: GO:0043043 {is_inferred="true"} ! peptide biosynthetic process
 is_a: GO:0044272 {is_inferred="true"} ! sulfur compound biosynthetic process
 is_a: GO:1901748 {is_inferred="true"} ! leukotriene D4 metabolic process
 
@@ -69828,6 +69831,7 @@
 is_a: GO:0001676 {is_inferred="true"} ! long-chain fatty acid metabolic process
 is_a: GO:0006691 {is_inferred="true"} ! leukotriene metabolic process
 is_a: GO:0031407 {is_inferred="true"} ! oxylipin metabolic process
+is_a: GO:0033559 {is_inferred="true"} ! unsaturated fatty acid metabolic process
 is_a: GO:0097176 {is_inferred="true"} ! epoxide metabolic process
 
 [Term]
@@ -69841,6 +69845,7 @@
 
 [Term]
 id: GO:1901753 ! leukotriene A4 biosynthetic process
+is_a: GO:0006636 {is_inferred="true"} ! unsaturated fatty acid biosynthetic process
 is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
 is_a: GO:0019370 {is_inferred="true"} ! leukotriene biosynthetic process
 is_a: GO:0031408 {is_inferred="true"} ! oxylipin biosynthetic process
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 39079)
+++ go_inferences.obo	(working copy)
@@ -58775,6 +58775,10 @@
 is_a: GO:0060076 {is_inferred="true"} ! excitatory synapse
 
 [Term]
+id: GO:0098689 ! latency-replication decision
+is_a: GO:0050792 {is_inferred="true"} ! regulation of viral process
+
+[Term]
 id: GO:0098700 ! neurotransmitter loading into synaptic vesicle
 is_a: GO:0006836 {is_inferred="true"} ! neurotransmitter transport
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
@@ -90104,10 +90108,6 @@
 is_a: GO:0034504 {is_inferred="true"} ! protein localization to nucleus
 
 [Term]
-id: GO:1990032 ! parallel fiber
-is_a: GO:0044302 {is_inferred="true"} ! dentate gyrus mossy fiber
-
-[Term]
 id: GO:1990034 ! calcium ion export from cell
 is_a: GO:1901660 {is_inferred="true"} ! calcium ion export
 
------------------------------------------------------------------------
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 39055)
+++ go_inferences.obo	(working copy)
@@ -30761,18 +30761,6 @@
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 
 [Term]
-id: GO:0042091 ! interleukin-10 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
-id: GO:0042094 ! interleukin-2 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
-id: GO:0042097 ! interleukin-4 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
 id: GO:0042101 ! T cell receptor complex
 is_a: GO:0098802 {is_inferred="true"} ! plasma membrane receptor complex
 
@@ -30800,10 +30788,6 @@
 is_a: GO:0051247 {is_inferred="true"} ! positive regulation of protein metabolic process
 
 [Term]
-id: GO:0042109 ! lymphotoxin A biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
 id: GO:0042119 ! neutrophil activation
 is_a: GO:0036230 {is_inferred="true"} ! granulocyte activation
 
@@ -31111,74 +31095,6 @@
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
 [Term]
-id: GO:0042222 ! interleukin-1 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
-id: GO:0042223 ! interleukin-3 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
-id: GO:0042225 ! interleukin-5 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
-id: GO:0042226 ! interleukin-6 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
-id: GO:0042227 ! interleukin-7 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
-id: GO:0042228 ! interleukin-8 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
-id: GO:0042229 ! interleukin-9 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
-id: GO:0042230 ! interleukin-11 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
-id: GO:0042231 ! interleukin-13 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
-id: GO:0042233 ! interleukin-15 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
-id: GO:0042234 ! interleukin-16 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
-id: GO:0042235 ! interleukin-17 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
-id: GO:0042236 ! interleukin-19 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
-id: GO:0042237 ! interleukin-20 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
-id: GO:0042238 ! interleukin-21 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
-id: GO:0042239 ! interleukin-22 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
-id: GO:0042241 ! interleukin-18 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
 id: GO:0042243 ! asexual spore wall assembly
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 
@@ -31187,10 +31103,6 @@
 is_a: GO:0010927 {is_inferred="true"} ! cellular component assembly involved in morphogenesis
 
 [Term]
-id: GO:0042253 ! granulocyte macrophage colony-stimulating factor biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
 id: GO:0042255 ! ribosome assembly
 is_a: GO:0022618 {is_inferred="true"} ! ribonucleoprotein complex assembly
 
@@ -35410,10 +35322,6 @@
 is_a: GO:0034333 {is_inferred="true"} ! adherens junction assembly
 
 [Term]
-id: GO:0045189 ! connective tissue growth factor biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
 id: GO:0045190 ! isotype switching
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
@@ -35721,10 +35629,6 @@
 is_a: GO:0045346 {is_inferred="true"} ! regulation of MHC class II biosynthetic process
 
 [Term]
-id: GO:0045350 ! interferon-beta biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
 id: GO:0045354 ! regulation of interferon-alpha biosynthetic process
 is_a: GO:0032647 {is_inferred="true"} ! regulation of interferon-alpha production
 is_a: GO:0042035 {is_inferred="true"} ! regulation of cytokine biosynthetic process
@@ -36254,18 +36158,10 @@
 is_a: GO:0019975 {is_inferred="true"} ! interleukin-17 binding
 
 [Term]
-id: GO:0045524 ! interleukin-24 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
 id: GO:0045525 ! interleukin-25 biosynthetic process
 is_a: GO:0042235 {is_inferred="true"} ! interleukin-17 biosynthetic process
 
 [Term]
-id: GO:0045526 ! interleukin-26 biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
 id: GO:0045528 ! regulation of interleukin-24 biosynthetic process
 is_a: GO:0032668 {is_inferred="true"} ! regulation of interleukin-24 production
 is_a: GO:0042035 {is_inferred="true"} ! regulation of cytokine biosynthetic process
@@ -41202,10 +41098,6 @@
 is_a: GO:0048145 {is_inferred="true"} ! regulation of fibroblast proliferation
 
 [Term]
-id: GO:0048175 ! hepatocyte growth factor biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
 id: GO:0048176 ! regulation of hepatocyte growth factor biosynthetic process
 is_a: GO:0032646 {is_inferred="true"} ! regulation of hepatocyte growth factor production
 is_a: GO:0042035 {is_inferred="true"} ! regulation of cytokine biosynthetic process
@@ -42616,10 +42508,6 @@
 is_a: GO:0051248 {is_inferred="true"} ! negative regulation of protein metabolic process
 
 [Term]
-id: GO:0050751 ! fractalkine biosynthetic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-
-[Term]
 id: GO:0050752 ! regulation of fractalkine biosynthetic process
 is_a: GO:0032644 {is_inferred="true"} ! regulation of fractalkine production
 is_a: GO:0045073 {is_inferred="true"} ! regulation of chemokine biosynthetic process
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 39012)
+++ go_inferences.obo	(working copy)
@@ -90184,7 +90184,7 @@
 
 [Term]
 id: GO:1905962 ! glutamatergic neuron differentiation
-is_a: GO:0030154 {is_inferred="true"} ! cell differentiation
+is_a: GO:0030182 {is_inferred="true"} ! neuron differentiation
 
 [Term]
 id: GO:1905963 ! regulation of protein targeting to plasma membrane
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38983)
+++ go_inferences.obo	(working copy)
@@ -32812,10 +32812,6 @@
 is_a: GO:0015159 {is_inferred="true"} ! polysaccharide transmembrane transporter activity
 
 [Term]
-id: GO:0042964 ! thioredoxin biosynthetic process
-is_a: GO:0019538 {is_inferred="true"} ! protein metabolic process
-
-[Term]
 id: GO:0042967 ! acyl-carrier-protein biosynthetic process
 is_a: GO:0019538 {is_inferred="true"} ! protein metabolic process
 
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38982)
+++ go_inferences.obo	(working copy)
@@ -33165,10 +33165,6 @@
 is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
 
 [Term]
-id: GO:0043172 ! ferredoxin biosynthetic process
-is_a: GO:0006124 {is_inferred="true"} ! ferredoxin metabolic process
-
-[Term]
 id: GO:0043176 ! amine binding
 is_a: GO:0005488 {is_inferred="true"} ! binding
 
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Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38980)
+++ go_inferences.obo	(working copy)
@@ -32816,10 +32816,6 @@
 is_a: GO:0019538 {is_inferred="true"} ! protein metabolic process
 
 [Term]
-id: GO:0042965 ! glutaredoxin biosynthetic process
-is_a: GO:0019538 {is_inferred="true"} ! protein metabolic process
-
-[Term]
 id: GO:0042967 ! acyl-carrier-protein biosynthetic process
 is_a: GO:0019538 {is_inferred="true"} ! protein metabolic process
 
------------------------------------------------------------------------
r38978 | cjm | 2017-02-24 10:23:11 -0800 (Fri, 24 Feb 2017) | 1 line

synced

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38979)
+++ go_inferences.obo	(working copy)
@@ -90199,6 +90199,23 @@
 is_a: GO:0030154 {is_inferred="true"} ! cell differentiation
 
 [Term]
+id: GO:1905963 ! regulation of protein targeting to plasma membrane
+is_a: GO:0090003 {is_inferred="true"} ! regulation of establishment of protein localization to plasma membrane
+is_a: GO:0090313 {is_inferred="true"} ! regulation of protein targeting to membrane
+
+[Term]
+id: GO:1905964 ! negative regulation of protein targeting to plasma membrane
+is_a: GO:0090005 {is_inferred="true"} ! negative regulation of establishment of protein localization to plasma membrane
+is_a: GO:0090315 {is_inferred="true"} ! negative regulation of protein targeting to membrane
+is_a: GO:1905963 {is_inferred="true"} ! regulation of protein targeting to plasma membrane
+
+[Term]
+id: GO:1905965 ! positive regulation of protein targeting to plasma membrane
+is_a: GO:0090004 {is_inferred="true"} ! positive regulation of establishment of protein localization to plasma membrane
+is_a: GO:0090314 {is_inferred="true"} ! positive regulation of protein targeting to membrane
+is_a: GO:1905963 {is_inferred="true"} ! regulation of protein targeting to plasma membrane
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r38972 | davidos | 2017-02-23 11:56:02 -0800 (Thu, 23 Feb 2017) | 1 line

Added <Parallel fiber to Purkinje cell synapse>. Also some missing xrefs for BHF & delted some redundany axioms.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38972)
+++ go_inferences.obo	(working copy)
@@ -58895,6 +58895,10 @@
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
 
 [Term]
+id: GO:0098688 ! parallel fiber to Purkinje cell synapse
+is_a: GO:0060076 {is_inferred="true"} ! excitatory synapse
+
+[Term]
 id: GO:0098700 ! neurotransmitter loading into synaptic vesicle
 is_a: GO:0006836 {is_inferred="true"} ! neurotransmitter transport
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
@@ -90207,6 +90211,10 @@
 is_a: GO:0034504 {is_inferred="true"} ! protein localization to nucleus
 
 [Term]
+id: GO:1990032 ! parallel fiber
+is_a: GO:0044302 {is_inferred="true"} ! dentate gyrus mossy fiber
+
+[Term]
 id: GO:1990034 ! calcium ion export from cell
 is_a: GO:1901660 {is_inferred="true"} ! calcium ion export
 
------------------------------------------------------------------------
r38970 | termgenie | 2017-02-23 10:01:28 -0800 (Thu, 23 Feb 2017) | 2 lines

TermGenie commit for user: slaulederkind reviewed by cmungall

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38970)
+++ go_inferences.obo	(working copy)
@@ -90181,9 +90181,20 @@
 
 [Term]
 id: GO:1905960 ! response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one
-is_a: GO:0050896 {is_inferred="true"} ! response to stimulus
+is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
+is_a: GO:0045472 {is_inferred="true"} ! response to ether
+is_a: GO:1901654 {is_inferred="true"} ! response to ketone
 
 [Term]
+id: GO:1905961 ! protein-cysteine S-palmitoyltransferase complex
+is_a: GO:0002178 {is_inferred="true"} ! palmitoyltransferase complex
+is_a: GO:0043234 {is_inferred="true"} ! protein complex
+
+[Term]
+id: GO:1905962 ! glutamatergic neuron differentiation
+is_a: GO:0030154 {is_inferred="true"} ! cell differentiation
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r38954 | tberardi | 2017-02-22 11:06:44 -0800 (Wed, 22 Feb 2017) | 6 lines

Fixed bad PMID put in through TG:

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38954)
+++ go_inferences.obo	(working copy)
@@ -10468,19 +10468,19 @@
 [Term]
 id: GO:0009787 ! regulation of abscisic acid-activated signaling pathway
 is_a: GO:0009966 {is_inferred="true"} ! regulation of signal transduction
-is_a: GO:1901419 {is_inferred="true"} ! regulation of response to alcohol
+is_a: GO:1905957 {is_inferred="true"} ! regulation of cellular response to alcohol
 
 [Term]
 id: GO:0009788 ! negative regulation of abscisic acid-activated signaling pathway
 is_a: GO:0009787 {is_inferred="true"} ! regulation of abscisic acid-activated signaling pathway
 is_a: GO:0009968 {is_inferred="true"} ! negative regulation of signal transduction
-is_a: GO:1901420 {is_inferred="true"} ! negative regulation of response to alcohol
+is_a: GO:1905958 {is_inferred="true"} ! negative regulation of cellular response to alcohol
 
 [Term]
 id: GO:0009789 ! positive regulation of abscisic acid-activated signaling pathway
 is_a: GO:0009787 {is_inferred="true"} ! regulation of abscisic acid-activated signaling pathway
 is_a: GO:0009967 {is_inferred="true"} ! positive regulation of signal transduction
-is_a: GO:1901421 {is_inferred="true"} ! positive regulation of response to alcohol
+is_a: GO:1905959 {is_inferred="true"} ! positive regulation of cellular response to alcohol
 
 [Term]
 id: GO:0009793 ! embryo development ending in seed dormancy
@@ -12924,13 +12924,13 @@
 
 [Term]
 id: GO:0010883 ! regulation of lipid storage
-is_a: GO:0032879 {is_inferred="true"} ! regulation of localization
 is_a: GO:0065008 {is_inferred="true"} ! regulation of biological quality
+is_a: GO:1905952 {is_inferred="true"} ! regulation of lipid localization
 
 [Term]
 id: GO:0010884 ! positive regulation of lipid storage
 is_a: GO:0010883 {is_inferred="true"} ! regulation of lipid storage
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
+is_a: GO:1905954 {is_inferred="true"} ! positive regulation of lipid localization
 
 [Term]
 id: GO:0010885 ! regulation of cholesterol storage
@@ -12949,7 +12949,7 @@
 [Term]
 id: GO:0010888 ! negative regulation of lipid storage
 is_a: GO:0010883 {is_inferred="true"} ! regulation of lipid storage
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
+is_a: GO:1905953 {is_inferred="true"} ! negative regulation of lipid localization
 
 [Term]
 id: GO:0010889 ! regulation of sequestering of triglyceride
@@ -23456,6 +23456,18 @@
 is_a: GO:0032366 {is_inferred="true"} ! intracellular sterol transport
 
 [Term]
+id: GO:0032368 ! regulation of lipid transport
+is_a: GO:1905952 {is_inferred="true"} ! regulation of lipid localization
+
+[Term]
+id: GO:0032369 ! negative regulation of lipid transport
+is_a: GO:1905953 {is_inferred="true"} ! negative regulation of lipid localization
+
+[Term]
+id: GO:0032370 ! positive regulation of lipid transport
+is_a: GO:1905954 {is_inferred="true"} ! positive regulation of lipid localization
+
+[Term]
 id: GO:0032371 ! regulation of sterol transport
 is_a: GO:0032368 {is_inferred="true"} ! regulation of lipid transport
 
@@ -28947,7 +28959,7 @@
 [Term]
 id: GO:0035428 ! hexose transmembrane transport
 is_a: GO:0008645 {is_inferred="true"} ! hexose transport
-is_a: GO:0034219 {is_inferred="true"} ! carbohydrate transmembrane transport
+is_a: GO:1905950 {is_inferred="true"} ! monosaccharide transmembrane transport
 
 [Term]
 id: GO:0035429 ! gluconate transmembrane transport
@@ -90115,6 +90127,63 @@
 is_a: GO:1905664 {is_inferred="true"} ! regulation of calcium ion import across plasma membrane
 
 [Term]
+id: GO:1905950 ! monosaccharide transmembrane transport
+is_a: GO:0015749 {is_inferred="true"} ! monosaccharide transport
+is_a: GO:0034219 {is_inferred="true"} ! carbohydrate transmembrane transport
+
+[Term]
+id: GO:1905951 ! mitochondrion DNA recombination
+is_a: GO:0006310 {is_inferred="true"} ! DNA recombination
+is_a: GO:0032042 {is_inferred="true"} ! mitochondrial DNA metabolic process
+
+[Term]
+id: GO:1905952 ! regulation of lipid localization
+is_a: GO:0032879 {is_inferred="true"} ! regulation of localization
+
+[Term]
+id: GO:1905953 ! negative regulation of lipid localization
+is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
+is_a: GO:1905952 {is_inferred="true"} ! regulation of lipid localization
+
+[Term]
+id: GO:1905954 ! positive regulation of lipid localization
+is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
+is_a: GO:1905952 {is_inferred="true"} ! regulation of lipid localization
+
+[Term]
+id: GO:1905955 ! negative regulation of endothelial tube morphogenesis
+is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
+is_a: GO:1901509 {is_inferred="true"} ! regulation of endothelial tube morphogenesis
+is_a: GO:1905331 {is_inferred="true"} ! negative regulation of morphogenesis of an epithelium
+
+[Term]
+id: GO:1905956 ! positive regulation of endothelial tube morphogenesis
+is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
+is_a: GO:1901509 {is_inferred="true"} ! regulation of endothelial tube morphogenesis
+is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
+
+[Term]
+id: GO:1905957 ! regulation of cellular response to alcohol
+is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
+is_a: GO:1901419 {is_inferred="true"} ! regulation of response to alcohol
+
+[Term]
+id: GO:1905958 ! negative regulation of cellular response to alcohol
+is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
+is_a: GO:1901420 {is_inferred="true"} ! negative regulation of response to alcohol
+is_a: GO:1905957 {is_inferred="true"} ! regulation of cellular response to alcohol
+
+[Term]
+id: GO:1905959 ! positive regulation of cellular response to alcohol
+is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
+is_a: GO:1901421 {is_inferred="true"} ! positive regulation of response to alcohol
+is_a: GO:1905957 {is_inferred="true"} ! regulation of cellular response to alcohol
+
+[Term]
+id: GO:1905960 ! response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one
+is_a: GO:0050896 {is_inferred="true"} ! response to stimulus
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r38941 | paola | 2017-02-22 02:07:51 -0800 (Wed, 22 Feb 2017) | 3 lines

GH Export vs transmembrane export #11784 - closed - edited ‘ferrous iron export’

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38941)
+++ go_inferences.obo	(working copy)
@@ -2356,7 +2356,6 @@
 
 [Term]
 id: GO:0002392 ! platelet activating factor secretion
-is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 is_a: GO:0015697 {is_inferred="true"} ! quaternary ammonium group transport
 is_a: GO:0015914 {is_inferred="true"} ! phospholipid transport
 
@@ -4813,7 +4812,6 @@
 is_a: GO:0000295 {is_inferred="true"} ! adenine nucleotide transmembrane transporter activity
 is_a: GO:0005346 {is_inferred="true"} ! purine ribonucleotide transmembrane transporter activity
 is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
-is_a: GO:0015211 {is_inferred="true"} ! purine nucleoside transmembrane transporter activity
 
 [Term]
 id: GO:0005350 ! pyrimidine nucleobase transmembrane transporter activity
@@ -4941,7 +4939,6 @@
 
 [Term]
 id: GO:0005524 ! ATP binding
-is_a: GO:0032550 {is_inferred="true"} ! purine ribonucleoside binding
 is_a: GO:0032559 {is_inferred="true"} ! adenyl ribonucleotide binding
 is_a: GO:0035639 {is_inferred="true"} ! purine ribonucleoside triphosphate binding
 
@@ -5988,7 +5985,6 @@
 is_a: GO:0009152 {is_inferred="true"} ! purine ribonucleotide biosynthetic process
 is_a: GO:0009168 {is_inferred="true"} ! purine ribonucleoside monophosphate biosynthetic process
 is_a: GO:0046033 {is_inferred="true"} ! AMP metabolic process
-is_a: GO:0046129 {is_inferred="true"} ! purine ribonucleoside biosynthetic process
 
 [Term]
 id: GO:0006170 ! dAMP biosynthetic process
@@ -6008,7 +6004,6 @@
 is_a: GO:0009168 {is_inferred="true"} ! purine ribonucleoside monophosphate biosynthetic process
 is_a: GO:0009180 {is_inferred="true"} ! purine ribonucleoside diphosphate biosynthetic process
 is_a: GO:0046031 {is_inferred="true"} ! ADP metabolic process
-is_a: GO:0046129 {is_inferred="true"} ! purine ribonucleoside biosynthetic process
 
 [Term]
 id: GO:0006173 ! dADP biosynthetic process
@@ -6091,7 +6086,6 @@
 is_a: GO:0009154 {is_inferred="true"} ! purine ribonucleotide catabolic process
 is_a: GO:0009169 {is_inferred="true"} ! purine ribonucleoside monophosphate catabolic process
 is_a: GO:0046033 {is_inferred="true"} ! AMP metabolic process
-is_a: GO:0046130 {is_inferred="true"} ! purine ribonucleoside catabolic process
 
 [Term]
 id: GO:0006198 ! cAMP catabolic process
@@ -7449,7 +7443,6 @@
 is_a: GO:0009168 {is_inferred="true"} ! purine ribonucleoside monophosphate biosynthetic process
 is_a: GO:0009206 {is_inferred="true"} ! purine ribonucleoside triphosphate biosynthetic process
 is_a: GO:0046034 {is_inferred="true"} ! ATP metabolic process
-is_a: GO:0046129 {is_inferred="true"} ! purine ribonucleoside biosynthetic process
 
 [Term]
 id: GO:0006760 ! folic acid-containing compound metabolic process
@@ -8592,6 +8585,7 @@
 [Term]
 id: GO:0008320 ! protein transmembrane transporter activity
 is_a: GO:0008565 {is_inferred="true"} ! protein transporter activity
+is_a: GO:1904680 {is_inferred="true"} ! peptide transmembrane transporter activity
 
 [Term]
 id: GO:0008324 ! cation transmembrane transporter activity
@@ -8724,6 +8718,10 @@
 is_a: GO:0019829 {is_inferred="true"} ! cation-transporting ATPase activity
 
 [Term]
+id: GO:0008565 ! protein transporter activity
+is_a: GO:0015197 {is_inferred="true"} ! peptide transporter activity
+
+[Term]
 id: GO:0008582 ! regulation of synaptic growth at neuromuscular junction
 is_a: GO:0048638 {is_inferred="true"} ! regulation of developmental growth
 is_a: GO:0051963 {is_inferred="true"} ! regulation of synapse assembly
@@ -9833,6 +9831,10 @@
 is_a: GO:0098781 {is_inferred="true"} ! ncRNA transcription
 
 [Term]
+id: GO:0009306 ! protein secretion
+is_a: GO:0002790 {is_inferred="true"} ! peptide secretion
+
+[Term]
 id: GO:0009309 ! amine biosynthetic process
 is_a: GO:0009308 {is_inferred="true"} ! amine metabolic process
 is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
@@ -13971,6 +13973,10 @@
 is_a: GO:0044711 {is_inferred="true"} ! single-organism biosynthetic process
 
 [Term]
+id: GO:0015031 ! protein transport
+is_a: GO:0015833 {is_inferred="true"} ! peptide transport
+
+[Term]
 id: GO:0015050 ! methane monooxygenase complex
 is_a: GO:1990204 {is_inferred="true"} ! oxidoreductase complex
 
@@ -14078,6 +14084,7 @@
 
 [Term]
 id: GO:0015143 ! urate transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:1901702 {is_inferred="true"} ! salt transmembrane transporter activity
 
 [Term]
@@ -14272,7 +14279,6 @@
 
 [Term]
 id: GO:0015199 ! amino-acid betaine transmembrane transporter activity
-is_a: GO:0008519 {is_inferred="true"} ! ammonium transmembrane transporter activity
 is_a: GO:0015651 {is_inferred="true"} ! quaternary ammonium group transmembrane transporter activity
 is_a: GO:0072349 {is_inferred="true"} ! modified amino acid transmembrane transporter activity
 
@@ -14330,7 +14336,6 @@
 is_a: GO:0000295 {is_inferred="true"} ! adenine nucleotide transmembrane transporter activity
 is_a: GO:0005346 {is_inferred="true"} ! purine ribonucleotide transmembrane transporter activity
 is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
-is_a: GO:0015211 {is_inferred="true"} ! purine nucleoside transmembrane transporter activity
 
 [Term]
 id: GO:0015218 ! pyrimidine nucleotide transmembrane transporter activity
@@ -14787,6 +14792,10 @@
 is_a: GO:1901505 {is_inferred="true"} ! carbohydrate derivative transporter activity
 
 [Term]
+id: GO:0015651 ! quaternary ammonium group transmembrane transporter activity
+is_a: GO:0008519 {is_inferred="true"} ! ammonium transmembrane transporter activity
+
+[Term]
 id: GO:0015654 ! tellurite uptake transmembrane transporter activity
 is_a: GO:0015118 {is_inferred="true"} ! tellurite transmembrane transporter activity
 is_a: GO:0015563 {is_inferred="true"} ! uptake transmembrane transporter activity
@@ -14868,8 +14877,7 @@
 
 [Term]
 id: GO:0015685 ! ferric-enterobactin transport
-is_a: GO:0015688 {is_inferred="true"} ! iron chelate transport
-is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
+is_a: GO:0042930 {is_inferred="true"} ! enterobactin transport
 
 [Term]
 id: GO:0015686 ! ferric triacetylfusarinine C transport
@@ -14877,6 +14885,11 @@
 is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
+id: GO:0015687 ! ferric-hydroxamate transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
+is_a: GO:0042886 {is_inferred="true"} ! amide transport
+
+[Term]
 id: GO:0015688 ! iron chelate transport
 is_a: GO:1901678 {is_inferred="true"} ! iron coordination entity transport
 
@@ -14908,8 +14921,8 @@
 
 [Term]
 id: GO:0015697 ! quaternary ammonium group transport
+is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
 id: GO:0015698 ! inorganic anion transport
@@ -15585,7 +15598,6 @@
 [Term]
 id: GO:0015866 ! ADP transport
 is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
-is_a: GO:0015858 {is_inferred="true"} ! nucleoside transport
 is_a: GO:0015868 {is_inferred="true"} ! purine ribonucleotide transport
 is_a: GO:0051503 {is_inferred="true"} ! adenine nucleotide transport
 
@@ -15592,7 +15604,6 @@
 [Term]
 id: GO:0015867 ! ATP transport
 is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
-is_a: GO:0015858 {is_inferred="true"} ! nucleoside transport
 is_a: GO:0015868 {is_inferred="true"} ! purine ribonucleotide transport
 is_a: GO:0051503 {is_inferred="true"} ! adenine nucleotide transport
 
@@ -15636,13 +15647,11 @@
 
 [Term]
 id: GO:0015879 ! carnitine transport
-is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 is_a: GO:0015838 {is_inferred="true"} ! amino-acid betaine transport
 
 [Term]
 id: GO:0015880 ! coenzyme A transport
 is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
-is_a: GO:0015858 {is_inferred="true"} ! nucleoside transport
 is_a: GO:0015868 {is_inferred="true"} ! purine ribonucleotide transport
 is_a: GO:0051503 {is_inferred="true"} ! adenine nucleotide transport
 
@@ -15702,6 +15711,11 @@
 is_a: GO:1901264 {is_inferred="true"} ! carbohydrate derivative transport
 
 [Term]
+id: GO:0015894 ! acriflavine transport
+is_a: GO:0006821 {is_inferred="true"} ! chloride transport
+is_a: GO:0015695 {is_inferred="true"} ! organic cation transport
+
+[Term]
 id: GO:0015895 ! alkane transport
 is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 
@@ -15815,7 +15829,6 @@
 is_a: GO:0009150 {is_inferred="true"} ! purine ribonucleotide metabolic process
 is_a: GO:0033875 {is_inferred="true"} ! ribonucleoside bisphosphate metabolic process
 is_a: GO:0034032 {is_inferred="true"} ! purine nucleoside bisphosphate metabolic process
-is_a: GO:0046128 {is_inferred="true"} ! purine ribonucleoside metabolic process
 
 [Term]
 id: GO:0015937 ! coenzyme A biosynthetic process
@@ -15823,7 +15836,6 @@
 is_a: GO:0015936 {is_inferred="true"} ! coenzyme A metabolic process
 is_a: GO:0034030 {is_inferred="true"} ! ribonucleoside bisphosphate biosynthetic process
 is_a: GO:0034033 {is_inferred="true"} ! purine nucleoside bisphosphate biosynthetic process
-is_a: GO:0046129 {is_inferred="true"} ! purine ribonucleoside biosynthetic process
 
 [Term]
 id: GO:0015938 ! coenzyme A catabolic process
@@ -15831,7 +15843,6 @@
 is_a: GO:0015936 {is_inferred="true"} ! coenzyme A metabolic process
 is_a: GO:0034031 {is_inferred="true"} ! ribonucleoside bisphosphate catabolic process
 is_a: GO:0034034 {is_inferred="true"} ! purine nucleoside bisphosphate catabolic process
-is_a: GO:0046130 {is_inferred="true"} ! purine ribonucleoside catabolic process
 
 [Term]
 id: GO:0015939 ! pantothenate metabolic process
@@ -16447,7 +16458,6 @@
 
 [Term]
 id: GO:0016208 ! AMP binding
-is_a: GO:0032550 {is_inferred="true"} ! purine ribonucleoside binding
 is_a: GO:0032559 {is_inferred="true"} ! adenyl ribonucleotide binding
 is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:0043169 {is_inferred="true"} ! cation binding
@@ -17077,6 +17087,8 @@
 [Term]
 id: GO:0018923 ! limonene metabolic process
 is_a: GO:0043692 {is_inferred="true"} ! monoterpene metabolic process
+is_a: GO:1900673 {is_inferred="true"} ! olefin metabolic process
+is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
 
 [Term]
 id: GO:0018924 ! mandelate metabolic process
@@ -17876,7 +17888,6 @@
 id: GO:0019361 ! 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic process
 is_a: GO:0009152 {is_inferred="true"} ! purine ribonucleotide biosynthetic process
 is_a: GO:0009168 {is_inferred="true"} ! purine ribonucleoside monophosphate biosynthetic process
-is_a: GO:0046129 {is_inferred="true"} ! purine ribonucleoside biosynthetic process
 is_a: GO:0046432 {is_inferred="true"} ! 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA metabolic process
 
 [Term]
@@ -19313,6 +19324,7 @@
 
 [Term]
 id: GO:0020028 ! hemoglobin import
+is_a: GO:0015886 {is_inferred="true"} ! heme transport
 is_a: GO:0017038 {is_inferred="true"} ! protein import
 
 [Term]
@@ -19693,10 +19705,6 @@
 is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
 
 [Term]
-id: GO:0022885 ! bacteriocin transmembrane transporter activity
-is_a: GO:1904680 {is_inferred="true"} ! peptide transmembrane transporter activity
-
-[Term]
 id: GO:0022889 ! serine transmembrane transporter activity
 is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
 
@@ -19922,8 +19930,7 @@
 [Term]
 id: GO:0030170 ! pyridoxal phosphate binding
 is_a: GO:0043168 {is_inferred="true"} ! anion binding
-is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
-is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
+is_a: GO:0070279 {is_inferred="true"} ! vitamin B6 binding
 
 [Term]
 id: GO:0030173 ! integral component of Golgi membrane
@@ -21979,7 +21986,6 @@
 
 [Term]
 id: GO:0031460 ! glycine betaine transport
-is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 is_a: GO:0015838 {is_inferred="true"} ! amino-acid betaine transport
 is_a: GO:0072337 {is_inferred="true"} ! modified amino acid transport
 
@@ -22449,7 +22455,7 @@
 is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015748 {is_inferred="true"} ! organophosphate ester transport
 is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
+is_a: GO:0031919 {is_inferred="true"} ! vitamin B6 transport
 
 [Term]
 id: GO:0031922 ! pyridoxamine transport
@@ -22473,6 +22479,8 @@
 id: GO:0031926 ! pyridoxal phosphate transmembrane transporter activity
 is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:0015605 {is_inferred="true"} ! organophosphate ester transmembrane transporter activity
+is_a: GO:0031924 {is_inferred="true"} ! vitamin B6 transporter activity
+is_a: GO:0090482 {is_inferred="true"} ! vitamin transmembrane transporter activity
 is_a: GO:1901618 {is_inferred="true"} ! organic hydroxy compound transmembrane transporter activity
 
 [Term]
@@ -23419,10 +23427,10 @@
 [Term]
 id: GO:0032361 ! pyridoxal phosphate catabolic process
 is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
+is_a: GO:0042820 {is_inferred="true"} ! vitamin B6 catabolic process
 is_a: GO:0042822 {is_inferred="true"} ! pyridoxal phosphate metabolic process
 is_a: GO:0046185 {is_inferred="true"} ! aldehyde catabolic process
 is_a: GO:0046434 {is_inferred="true"} ! organophosphate catabolic process
-is_a: GO:0072526 {is_inferred="true"} ! pyridine-containing compound catabolic process
 is_a: GO:1901616 {is_inferred="true"} ! organic hydroxy compound catabolic process
 
 [Term]
@@ -27929,13 +27937,13 @@
 is_a: GO:0050748 {is_inferred="true"} ! negative regulation of lipoprotein metabolic process
 
 [Term]
-id: GO:0034444 ! regulation of plasma lipoprotein particle oxidation
+id: GO:0034444 ! regulation of plasma lipoprotein oxidation
 is_a: GO:0034442 {is_inferred="true"} ! regulation of lipoprotein oxidation
 
 [Term]
-id: GO:0034445 ! negative regulation of plasma lipoprotein particle oxidation
+id: GO:0034445 ! negative regulation of plasma lipoprotein oxidation
 is_a: GO:0034443 {is_inferred="true"} ! negative regulation of lipoprotein oxidation
-is_a: GO:0034444 {is_inferred="true"} ! regulation of plasma lipoprotein particle oxidation
+is_a: GO:0034444 {is_inferred="true"} ! regulation of plasma lipoprotein oxidation
 
 [Term]
 id: GO:0034446 ! substrate adhesion-dependent cell spreading
@@ -32312,15 +32320,15 @@
 is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
 is_a: GO:0006796 {is_inferred="true"} ! phosphate-containing compound metabolic process
 is_a: GO:0019637 {is_inferred="true"} ! organophosphate metabolic process
-is_a: GO:0072524 {is_inferred="true"} ! pyridine-containing compound metabolic process
+is_a: GO:0042816 {is_inferred="true"} ! vitamin B6 metabolic process
 is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
 
 [Term]
 id: GO:0042823 ! pyridoxal phosphate biosynthetic process
 is_a: GO:0019438 {is_inferred="true"} ! aromatic compound biosynthetic process
+is_a: GO:0042819 {is_inferred="true"} ! vitamin B6 biosynthetic process
 is_a: GO:0042822 {is_inferred="true"} ! pyridoxal phosphate metabolic process
 is_a: GO:0046184 {is_inferred="true"} ! aldehyde biosynthetic process
-is_a: GO:0072525 {is_inferred="true"} ! pyridine-containing compound biosynthetic process
 is_a: GO:0090407 {is_inferred="true"} ! organophosphate biosynthetic process
 is_a: GO:1901617 {is_inferred="true"} ! organic hydroxy compound biosynthetic process
 
@@ -33910,7 +33918,6 @@
 
 [Term]
 id: GO:0043531 ! ADP binding
-is_a: GO:0032550 {is_inferred="true"} ! purine ribonucleoside binding
 is_a: GO:0032559 {is_inferred="true"} ! adenyl ribonucleotide binding
 is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
@@ -34530,10 +34537,6 @@
 is_a: GO:0043097 {is_inferred="true"} ! pyrimidine nucleoside salvage
 
 [Term]
-id: GO:0044209 ! AMP salvage
-is_a: GO:0006166 {is_inferred="true"} ! purine ribonucleoside salvage
-
-[Term]
 id: GO:0044211 ! CTP salvage
 is_a: GO:0043097 {is_inferred="true"} ! pyrimidine nucleoside salvage
 
@@ -38073,7 +38076,6 @@
 is_a: GO:0009150 {is_inferred="true"} ! purine ribonucleotide metabolic process
 is_a: GO:0009167 {is_inferred="true"} ! purine ribonucleoside monophosphate metabolic process
 is_a: GO:0009179 {is_inferred="true"} ! purine ribonucleoside diphosphate metabolic process
-is_a: GO:0046128 {is_inferred="true"} ! purine ribonucleoside metabolic process
 
 [Term]
 id: GO:0046032 ! ADP catabolic process
@@ -38081,13 +38083,11 @@
 is_a: GO:0009169 {is_inferred="true"} ! purine ribonucleoside monophosphate catabolic process
 is_a: GO:0009181 {is_inferred="true"} ! purine ribonucleoside diphosphate catabolic process
 is_a: GO:0046031 {is_inferred="true"} ! ADP metabolic process
-is_a: GO:0046130 {is_inferred="true"} ! purine ribonucleoside catabolic process
 
 [Term]
 id: GO:0046033 ! AMP metabolic process
 is_a: GO:0009150 {is_inferred="true"} ! purine ribonucleotide metabolic process
 is_a: GO:0009167 {is_inferred="true"} ! purine ribonucleoside monophosphate metabolic process
-is_a: GO:0046128 {is_inferred="true"} ! purine ribonucleoside metabolic process
 
 [Term]
 id: GO:0046034 ! ATP metabolic process
@@ -38094,7 +38094,6 @@
 is_a: GO:0009150 {is_inferred="true"} ! purine ribonucleotide metabolic process
 is_a: GO:0009167 {is_inferred="true"} ! purine ribonucleoside monophosphate metabolic process
 is_a: GO:0009205 {is_inferred="true"} ! purine ribonucleoside triphosphate metabolic process
-is_a: GO:0046128 {is_inferred="true"} ! purine ribonucleoside metabolic process
 
 [Term]
 id: GO:0046035 ! CMP metabolic process
@@ -39053,11 +39052,14 @@
 id: GO:0046250 ! limonene biosynthetic process
 is_a: GO:0018923 {is_inferred="true"} ! limonene metabolic process
 is_a: GO:0043693 {is_inferred="true"} ! monoterpene biosynthetic process
+is_a: GO:1900674 {is_inferred="true"} ! olefin biosynthetic process
+is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
 
 [Term]
 id: GO:0046251 ! limonene catabolic process
 is_a: GO:0018923 {is_inferred="true"} ! limonene metabolic process
 is_a: GO:0043694 {is_inferred="true"} ! monoterpene catabolic process
+is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
 
 [Term]
 id: GO:0046252 ! toluene biosynthetic process
@@ -39736,7 +39738,6 @@
 id: GO:0046432 ! 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA metabolic process
 is_a: GO:0009150 {is_inferred="true"} ! purine ribonucleotide metabolic process
 is_a: GO:0009167 {is_inferred="true"} ! purine ribonucleoside monophosphate metabolic process
-is_a: GO:0046128 {is_inferred="true"} ! purine ribonucleoside metabolic process
 
 [Term]
 id: GO:0046433 ! 2-aminoethylphosphonate metabolic process
@@ -40908,7 +40909,6 @@
 [Term]
 id: GO:0046963 ! 3'-phosphoadenosine 5'-phosphosulfate transport
 is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
-is_a: GO:0015858 {is_inferred="true"} ! nucleoside transport
 is_a: GO:0015868 {is_inferred="true"} ! purine ribonucleotide transport
 is_a: GO:0051503 {is_inferred="true"} ! adenine nucleotide transport
 is_a: GO:0072348 {is_inferred="true"} ! sulfur compound transport
@@ -40918,7 +40918,6 @@
 is_a: GO:0000295 {is_inferred="true"} ! adenine nucleotide transmembrane transporter activity
 is_a: GO:0005346 {is_inferred="true"} ! purine ribonucleotide transmembrane transporter activity
 is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
-is_a: GO:0015211 {is_inferred="true"} ! purine nucleoside transmembrane transporter activity
 is_a: GO:1901682 {is_inferred="true"} ! sulfur compound transmembrane transporter activity
 
 [Term]
@@ -42303,7 +42302,6 @@
 is_a: GO:0009150 {is_inferred="true"} ! purine ribonucleotide metabolic process
 is_a: GO:0034035 {is_inferred="true"} ! purine ribonucleoside bisphosphate metabolic process
 is_a: GO:0043436 {is_inferred="true"} ! oxoacid metabolic process
-is_a: GO:0046128 {is_inferred="true"} ! purine ribonucleoside metabolic process
 
 [Term]
 id: GO:0050428 ! 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process
@@ -42310,7 +42308,6 @@
 is_a: GO:0009152 {is_inferred="true"} ! purine ribonucleotide biosynthetic process
 is_a: GO:0034036 {is_inferred="true"} ! purine ribonucleoside bisphosphate biosynthetic process
 is_a: GO:0044272 {is_inferred="true"} ! sulfur compound biosynthetic process
-is_a: GO:0046129 {is_inferred="true"} ! purine ribonucleoside biosynthetic process
 is_a: GO:0050427 {is_inferred="true"} ! 3'-phosphoadenosine 5'-phosphosulfate metabolic process
 
 [Term]
@@ -42384,7 +42381,6 @@
 
 [Term]
 id: GO:0050656 ! 3'-phosphoadenosine 5'-phosphosulfate binding
-is_a: GO:0032550 {is_inferred="true"} ! purine ribonucleoside binding
 is_a: GO:0032559 {is_inferred="true"} ! adenyl ribonucleotide binding
 is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:1901681 {is_inferred="true"} ! sulfur compound binding
@@ -42504,6 +42500,14 @@
 is_a: GO:0050708 {is_inferred="true"} ! regulation of protein secretion
 
 [Term]
+id: GO:0050708 ! regulation of protein secretion
+is_a: GO:0002791 {is_inferred="true"} ! regulation of peptide secretion
+
+[Term]
+id: GO:0050709 ! negative regulation of protein secretion
+is_a: GO:0002792 {is_inferred="true"} ! negative regulation of peptide secretion
+
+[Term]
 id: GO:0050710 ! negative regulation of cytokine secretion
 is_a: GO:0001818 {is_inferred="true"} ! negative regulation of cytokine production
 is_a: GO:0050707 {is_inferred="true"} ! regulation of cytokine secretion
@@ -42525,6 +42529,10 @@
 is_a: GO:0050711 {is_inferred="true"} ! negative regulation of interleukin-1 secretion
 
 [Term]
+id: GO:0050714 ! positive regulation of protein secretion
+is_a: GO:0002793 {is_inferred="true"} ! positive regulation of peptide secretion
+
+[Term]
 id: GO:0050715 ! positive regulation of cytokine secretion
 is_a: GO:0001819 {is_inferred="true"} ! positive regulation of cytokine production
 is_a: GO:0050707 {is_inferred="true"} ! regulation of cytokine secretion
@@ -43612,6 +43620,10 @@
 is_a: GO:0032507 {is_inferred="true"} ! maintenance of protein location in cell
 
 [Term]
+id: GO:0051223 ! regulation of protein transport
+is_a: GO:0090087 {is_inferred="true"} ! regulation of peptide transport
+
+[Term]
 id: GO:0051228 ! mitotic spindle disassembly
 is_a: GO:0007052 {is_inferred="true"} ! mitotic spindle organization
 is_a: GO:0051230 {is_inferred="true"} ! spindle disassembly
@@ -49136,6 +49148,7 @@
 
 [Term]
 id: GO:0061684 ! chaperone-mediated autophagy
+is_a: GO:0006518 {is_inferred="true"} ! peptide metabolic process
 is_a: GO:0030163 {is_inferred="true"} ! protein catabolic process
 
 [Term]
@@ -51147,13 +51160,13 @@
 
 [Term]
 id: GO:0070926 ! regulation of ATP:ADP antiporter activity
-is_a: GO:0032242 {is_inferred="true"} ! regulation of nucleoside transport
+is_a: GO:0032239 {is_inferred="true"} ! regulation of nucleobase-containing compound transport
 is_a: GO:0032412 {is_inferred="true"} ! regulation of ion transmembrane transporter activity
 is_a: GO:1903959 {is_inferred="true"} ! regulation of anion transmembrane transport
 
 [Term]
 id: GO:0070927 ! negative regulation of ATP:ADP antiporter activity
-is_a: GO:0032243 {is_inferred="true"} ! negative regulation of nucleoside transport
+is_a: GO:0032240 {is_inferred="true"} ! negative regulation of nucleobase-containing compound transport
 is_a: GO:0032413 {is_inferred="true"} ! negative regulation of ion transmembrane transporter activity
 is_a: GO:0070926 {is_inferred="true"} ! regulation of ATP:ADP antiporter activity
 is_a: GO:1903960 {is_inferred="true"} ! negative regulation of anion transmembrane transport
@@ -51522,9 +51535,9 @@
 
 [Term]
 id: GO:0071106 ! adenosine 3',5'-bisphosphate transmembrane transport
-is_a: GO:0015860 {is_inferred="true"} ! purine nucleoside transmembrane transport
 is_a: GO:0015868 {is_inferred="true"} ! purine ribonucleotide transport
 is_a: GO:0051503 {is_inferred="true"} ! adenine nucleotide transport
+is_a: GO:0072530 {is_inferred="true"} ! purine-containing compound transmembrane transport
 is_a: GO:1901679 {is_inferred="true"} ! nucleotide transmembrane transport
 
 [Term]
@@ -53384,11 +53397,13 @@
 
 [Term]
 id: GO:0071938 ! vitamin A transport
-is_a: GO:0046865 {is_inferred="true"} ! terpenoid transport
+is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
+is_a: GO:0034633 {is_inferred="true"} ! retinol transport
 
 [Term]
 id: GO:0071939 ! vitamin A import
 is_a: GO:0071938 {is_inferred="true"} ! vitamin A transport
+is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
 id: GO:0071947 ! protein deubiquitination involved in ubiquitin-dependent protein catabolic process
@@ -55483,7 +55498,6 @@
 
 [Term]
 id: GO:0080020 ! regulation of coenzyme A biosynthetic process
-is_a: GO:0009118 {is_inferred="true"} ! regulation of nucleoside metabolic process
 is_a: GO:0051196 {is_inferred="true"} ! regulation of coenzyme metabolic process
 is_a: GO:1900371 {is_inferred="true"} ! regulation of purine nucleotide biosynthetic process
 
@@ -55614,7 +55628,6 @@
 id: GO:0080121 ! AMP transport
 is_a: GO:0015695 {is_inferred="true"} ! organic cation transport
 is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
-is_a: GO:0015858 {is_inferred="true"} ! nucleoside transport
 is_a: GO:0015868 {is_inferred="true"} ! purine ribonucleotide transport
 is_a: GO:0051503 {is_inferred="true"} ! adenine nucleotide transport
 
@@ -55624,7 +55637,6 @@
 is_a: GO:0005346 {is_inferred="true"} ! purine ribonucleotide transmembrane transporter activity
 is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:0015101 {is_inferred="true"} ! organic cation transmembrane transporter activity
-is_a: GO:0015211 {is_inferred="true"} ! purine nucleoside transmembrane transporter activity
 
 [Term]
 id: GO:0080126 ! ovary septum development
@@ -64020,48 +64032,20 @@
 is_a: GO:1901663 {is_inferred="true"} ! quinone biosynthetic process
 
 [Term]
-id: GO:1900603 ! tensidol A metabolic process
-is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
-is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
-is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
-
-[Term]
 id: GO:1900604 ! tensidol A catabolic process
-is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
 is_a: GO:1900603 {is_inferred="true"} ! tensidol A metabolic process
-is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
-is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
 
 [Term]
 id: GO:1900605 ! tensidol A biosynthetic process
-is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
 is_a: GO:1900603 {is_inferred="true"} ! tensidol A metabolic process
-is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
-is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
 
 [Term]
-id: GO:1900606 ! tensidol B metabolic process
-is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
-is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
-is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
-
-[Term]
 id: GO:1900607 ! tensidol B catabolic process
-is_a: GO:0046395 {is_inferred="true"} ! carboxylic acid catabolic process
-is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
 is_a: GO:1900606 {is_inferred="true"} ! tensidol B metabolic process
-is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
-is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
 
 [Term]
 id: GO:1900608 ! tensidol B biosynthetic process
-is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
-is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 is_a: GO:1900606 {is_inferred="true"} ! tensidol B metabolic process
-is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
-is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
 
 [Term]
 id: GO:1900609 ! F-9775A metabolic process
@@ -64609,41 +64593,29 @@
 
 [Term]
 id: GO:1900707 ! regulation of tensidol A biosynthetic process
-is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
-is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
 is_a: GO:1900376 {is_inferred="true"} ! regulation of secondary metabolite biosynthetic process
 
 [Term]
 id: GO:1900708 ! negative regulation of tensidol A biosynthetic process
-is_a: GO:0031327 {is_inferred="true"} ! negative regulation of cellular biosynthetic process
-is_a: GO:0051172 {is_inferred="true"} ! negative regulation of nitrogen compound metabolic process
 is_a: GO:1900377 {is_inferred="true"} ! negative regulation of secondary metabolite biosynthetic process
 is_a: GO:1900707 {is_inferred="true"} ! regulation of tensidol A biosynthetic process
 
 [Term]
 id: GO:1900709 ! positive regulation of tensidol A biosynthetic process
-is_a: GO:0031328 {is_inferred="true"} ! positive regulation of cellular biosynthetic process
-is_a: GO:0051173 {is_inferred="true"} ! positive regulation of nitrogen compound metabolic process
 is_a: GO:1900378 {is_inferred="true"} ! positive regulation of secondary metabolite biosynthetic process
 is_a: GO:1900707 {is_inferred="true"} ! regulation of tensidol A biosynthetic process
 
 [Term]
 id: GO:1900710 ! regulation of tensidol B biosynthetic process
-is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
-is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
 is_a: GO:1900376 {is_inferred="true"} ! regulation of secondary metabolite biosynthetic process
 
 [Term]
 id: GO:1900711 ! negative regulation of tensidol B biosynthetic process
-is_a: GO:0031327 {is_inferred="true"} ! negative regulation of cellular biosynthetic process
-is_a: GO:0051172 {is_inferred="true"} ! negative regulation of nitrogen compound metabolic process
 is_a: GO:1900377 {is_inferred="true"} ! negative regulation of secondary metabolite biosynthetic process
 is_a: GO:1900710 {is_inferred="true"} ! regulation of tensidol B biosynthetic process
 
 [Term]
 id: GO:1900712 ! positive regulation of tensidol B biosynthetic process
-is_a: GO:0031328 {is_inferred="true"} ! positive regulation of cellular biosynthetic process
-is_a: GO:0051173 {is_inferred="true"} ! positive regulation of nitrogen compound metabolic process
 is_a: GO:1900378 {is_inferred="true"} ! positive regulation of secondary metabolite biosynthetic process
 is_a: GO:1900710 {is_inferred="true"} ! regulation of tensidol B biosynthetic process
 
@@ -64839,7 +64811,6 @@
 
 [Term]
 id: GO:1900751 ! 4-(trimethylammonio)butanoate transport
-is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 is_a: GO:0015838 {is_inferred="true"} ! amino-acid betaine transport
 
 [Term]
@@ -64924,17 +64895,29 @@
 
 [Term]
 id: GO:1900767 ! fonsecin metabolic process
+is_a: GO:0006066 {is_inferred="true"} ! alcohol metabolic process
+is_a: GO:0018904 {is_inferred="true"} ! ether metabolic process
+is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
+is_a: GO:0030638 {is_inferred="true"} ! polyketide metabolic process
 is_a: GO:1900785 {is_inferred="true"} ! naphtho-gamma-pyrone metabolic process
 
 [Term]
 id: GO:1900768 ! fonsecin catabolic process
+is_a: GO:0019336 {is_inferred="true"} ! phenol-containing compound catabolic process
+is_a: GO:0030640 {is_inferred="true"} ! polyketide catabolic process
+is_a: GO:0046164 {is_inferred="true"} ! alcohol catabolic process
 is_a: GO:1900767 {is_inferred="true"} ! fonsecin metabolic process
 is_a: GO:1900786 {is_inferred="true"} ! naphtho-gamma-pyrone catabolic process
+is_a: GO:1901502 {is_inferred="true"} ! ether catabolic process
 
 [Term]
 id: GO:1900769 ! fonsecin biosynthetic process
+is_a: GO:0030639 {is_inferred="true"} ! polyketide biosynthetic process
+is_a: GO:0046165 {is_inferred="true"} ! alcohol biosynthetic process
+is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
 is_a: GO:1900767 {is_inferred="true"} ! fonsecin metabolic process
 is_a: GO:1900787 {is_inferred="true"} ! naphtho-gamma-pyrone biosynthetic process
+is_a: GO:1901503 {is_inferred="true"} ! ether biosynthetic process
 
 [Term]
 id: GO:1900770 ! fumitremorgin B metabolic process
@@ -67454,7 +67437,6 @@
 
 [Term]
 id: GO:1901236 ! 4-(trimethylammonio)butanoate transmembrane transporter activity
-is_a: GO:0008519 {is_inferred="true"} ! ammonium transmembrane transporter activity
 is_a: GO:0015651 {is_inferred="true"} ! quaternary ammonium group transmembrane transporter activity
 
 [Term]
@@ -69198,7 +69180,9 @@
 [Term]
 id: GO:1901598 ! (-)-pinoresinol metabolic process
 is_a: GO:0009806 {is_inferred="true"} ! lignan metabolic process
+is_a: GO:0018904 {is_inferred="true"} ! ether metabolic process
 is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
+is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
 
 [Term]
@@ -69206,6 +69190,7 @@
 is_a: GO:0009807 {is_inferred="true"} ! lignan biosynthetic process
 is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
 is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
+is_a: GO:1901503 {is_inferred="true"} ! ether biosynthetic process
 is_a: GO:1901598 {is_inferred="true"} ! (-)-pinoresinol metabolic process
 
 [Term]
@@ -69681,7 +69666,8 @@
 
 [Term]
 id: GO:1901702 ! salt transmembrane transporter activity
-is_a: GO:0022857 {is_inferred="true"} ! transmembrane transporter activity
+is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
+is_a: GO:0008509 {is_inferred="true"} ! anion transmembrane transporter activity
 
 [Term]
 id: GO:1901703 ! protein localization involved in auxin polar transport
@@ -70806,13 +70792,11 @@
 id: GO:1901910 ! adenosine 5'-(hexahydrogen pentaphosphate) metabolic process
 is_a: GO:0009150 {is_inferred="true"} ! purine ribonucleotide metabolic process
 is_a: GO:0009167 {is_inferred="true"} ! purine ribonucleoside monophosphate metabolic process
-is_a: GO:0046128 {is_inferred="true"} ! purine ribonucleoside metabolic process
 
 [Term]
 id: GO:1901911 ! adenosine 5'-(hexahydrogen pentaphosphate) catabolic process
 is_a: GO:0009154 {is_inferred="true"} ! purine ribonucleotide catabolic process
 is_a: GO:0009169 {is_inferred="true"} ! purine ribonucleoside monophosphate catabolic process
-is_a: GO:0046130 {is_inferred="true"} ! purine ribonucleoside catabolic process
 is_a: GO:1901910 {is_inferred="true"} ! adenosine 5'-(hexahydrogen pentaphosphate) metabolic process
 
 [Term]
@@ -71872,12 +71856,15 @@
 is_a: GO:0019336 {is_inferred="true"} ! phenol-containing compound catabolic process
 is_a: GO:0046273 {is_inferred="true"} ! lignan catabolic process
 is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
+is_a: GO:1901502 {is_inferred="true"} ! ether catabolic process
 is_a: GO:1901598 {is_inferred="true"} ! (-)-pinoresinol metabolic process
 
 [Term]
 id: GO:1902124 ! (+)-pinoresinol metabolic process
 is_a: GO:0009806 {is_inferred="true"} ! lignan metabolic process
+is_a: GO:0018904 {is_inferred="true"} ! ether metabolic process
 is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
+is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
 
 [Term]
@@ -71885,6 +71872,7 @@
 is_a: GO:0019336 {is_inferred="true"} ! phenol-containing compound catabolic process
 is_a: GO:0046273 {is_inferred="true"} ! lignan catabolic process
 is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
+is_a: GO:1901502 {is_inferred="true"} ! ether catabolic process
 is_a: GO:1902124 {is_inferred="true"} ! (+)-pinoresinol metabolic process
 
 [Term]
@@ -71892,6 +71880,7 @@
 is_a: GO:0009807 {is_inferred="true"} ! lignan biosynthetic process
 is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
 is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
+is_a: GO:1901503 {is_inferred="true"} ! ether biosynthetic process
 is_a: GO:1902124 {is_inferred="true"} ! (+)-pinoresinol metabolic process
 
 [Term]
@@ -73916,23 +73905,22 @@
 is_a: GO:0000295 {is_inferred="true"} ! adenine nucleotide transmembrane transporter activity
 is_a: GO:0005346 {is_inferred="true"} ! purine ribonucleotide transmembrane transporter activity
 is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
-is_a: GO:0015211 {is_inferred="true"} ! purine nucleoside transmembrane transporter activity
 is_a: GO:1901682 {is_inferred="true"} ! sulfur compound transmembrane transporter activity
 
 [Term]
 id: GO:1902558 ! 5'-adenylyl sulfate transmembrane transport
 is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
-is_a: GO:0015860 {is_inferred="true"} ! purine nucleoside transmembrane transport
 is_a: GO:0015868 {is_inferred="true"} ! purine ribonucleotide transport
 is_a: GO:0051503 {is_inferred="true"} ! adenine nucleotide transport
 is_a: GO:0072348 {is_inferred="true"} ! sulfur compound transport
+is_a: GO:0072530 {is_inferred="true"} ! purine-containing compound transmembrane transport
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 is_a: GO:1901679 {is_inferred="true"} ! nucleotide transmembrane transport
 
 [Term]
 id: GO:1902559 ! 3'-phospho-5'-adenylyl sulfate transmembrane transport
-is_a: GO:0015860 {is_inferred="true"} ! purine nucleoside transmembrane transport
 is_a: GO:0046963 {is_inferred="true"} ! 3'-phosphoadenosine 5'-phosphosulfate transport
+is_a: GO:0072530 {is_inferred="true"} ! purine-containing compound transmembrane transport
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 is_a: GO:1901679 {is_inferred="true"} ! nucleotide transmembrane transport
 
@@ -74199,7 +74187,7 @@
 [Term]
 id: GO:1902616 ! acyl carnitine transmembrane transport
 is_a: GO:0006844 {is_inferred="true"} ! acyl carnitine transport
-is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
+is_a: GO:0072488 {is_inferred="true"} ! ammonium transmembrane transport
 
 [Term]
 id: GO:1902617 ! response to fluoride
@@ -78652,18 +78640,15 @@
 
 [Term]
 id: GO:1903578 ! regulation of ATP metabolic process
-is_a: GO:0009118 {is_inferred="true"} ! regulation of nucleoside metabolic process
 is_a: GO:1900542 {is_inferred="true"} ! regulation of purine nucleotide metabolic process
 
 [Term]
 id: GO:1903579 ! negative regulation of ATP metabolic process
-is_a: GO:0045978 {is_inferred="true"} ! negative regulation of nucleoside metabolic process
 is_a: GO:1900543 {is_inferred="true"} ! negative regulation of purine nucleotide metabolic process
 is_a: GO:1903578 {is_inferred="true"} ! regulation of ATP metabolic process
 
 [Term]
 id: GO:1903580 ! positive regulation of ATP metabolic process
-is_a: GO:0045979 {is_inferred="true"} ! positive regulation of nucleoside metabolic process
 is_a: GO:1900544 {is_inferred="true"} ! positive regulation of purine nucleotide metabolic process
 is_a: GO:1903578 {is_inferred="true"} ! regulation of ATP metabolic process
 
@@ -80636,7 +80621,7 @@
 is_a: GO:1904478 {is_inferred="true"} ! regulation of intestinal absorption
 
 [Term]
-id: GO:1903988 ! ferrous iron export
+id: GO:1903988 ! ferrous iron export across plasma membrane
 is_a: GO:0070839 {is_inferred="true"} ! divalent metal ion export
 is_a: GO:1903414 {is_inferred="true"} ! iron cation export
 
@@ -84144,11 +84129,13 @@
 [Term]
 id: GO:1904714 ! regulation of chaperone-mediated autophagy
 is_a: GO:0010506 {is_inferred="true"} ! regulation of autophagy
+is_a: GO:0034248 {is_inferred="true"} ! regulation of cellular amide metabolic process
 is_a: GO:0042176 {is_inferred="true"} ! regulation of protein catabolic process
 
 [Term]
 id: GO:1904715 ! negative regulation of chaperone-mediated autophagy
 is_a: GO:0010507 {is_inferred="true"} ! negative regulation of autophagy
+is_a: GO:0034249 {is_inferred="true"} ! negative regulation of cellular amide metabolic process
 is_a: GO:0042177 {is_inferred="true"} ! negative regulation of protein catabolic process
 is_a: GO:1904714 {is_inferred="true"} ! regulation of chaperone-mediated autophagy
 
@@ -84155,6 +84142,7 @@
 [Term]
 id: GO:1904716 ! positive regulation of chaperone-mediated autophagy
 is_a: GO:0010508 {is_inferred="true"} ! positive regulation of autophagy
+is_a: GO:0034250 {is_inferred="true"} ! positive regulation of cellular amide metabolic process
 is_a: GO:0045732 {is_inferred="true"} ! positive regulation of protein catabolic process
 is_a: GO:1904714 {is_inferred="true"} ! regulation of chaperone-mediated autophagy
 
@@ -90702,7 +90690,7 @@
 
 [Term]
 id: GO:1990544 ! mitochondrial ATP transmembrane transport
-is_a: GO:0015860 {is_inferred="true"} ! purine nucleoside transmembrane transport
+is_a: GO:0072530 {is_inferred="true"} ! purine-containing compound transmembrane transport
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 is_a: GO:1901679 {is_inferred="true"} ! nucleotide transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
------------------------------------------------------------------------
r38920 | mcourtot | 2017-02-20 01:04:16 -0800 (Mon, 20 Feb 2017) | 1 line

plant related TCs and pollination as per https://github.com/geneontology/go-ontology/issues/11313#issuecomment-280715396

changes in entailments

------------------------------------------------------------------------
r38880 | termgenie | 2017-02-17 09:58:02 -0800 (Fri, 17 Feb 2017) | 2 lines

TermGenie commit for user: bmeldal reviewed by tberardini

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38880)
+++ go_inferences.obo	(working copy)
@@ -90120,6 +90120,13 @@
 is_a: GO:0043225 {is_inferred="true"} ! ATPase-coupled anion transmembrane transporter activity
 
 [Term]
+id: GO:1905949 ! negative regulation of calcium ion import across plasma membrane
+is_a: GO:0010523 {is_inferred="true"} ! negative regulation of calcium ion transport into cytosol
+is_a: GO:0090281 {is_inferred="true"} ! negative regulation of calcium ion import
+is_a: GO:1903170 {is_inferred="true"} ! negative regulation of calcium ion transmembrane transport
+is_a: GO:1905664 {is_inferred="true"} ! regulation of calcium ion import across plasma membrane
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r38878 | mcourtot | 2017-02-17 07:10:52 -0800 (Fri, 17 Feb 2017) | 1 line

added id: GO:1905948 back which was not in gene_ontology_write.obo but was in validated file

changes in entailments

------------------------------------------------------------------------
r38870 | paola | 2017-02-17 05:04:26 -0800 (Fri, 17 Feb 2017) | 3 lines

GH NTR: children of cell pole #12007 - closed - edited defs of old/new cell pole terms

changes in entailments

------------------------------------------------------------------------
r38863 | termgenie | 2017-02-16 09:36:59 -0800 (Thu, 16 Feb 2017) | 2 lines

TermGenie commit for user: hattrill reviewed by tberardini

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38863)
+++ go_inferences.obo	(working copy)
@@ -90113,6 +90113,13 @@
 is_a: GO:1905945 {is_inferred="true"} ! regulation of response to calcium ion
 
 [Term]
+id: GO:1905948 ! 3',5'-cyclic GMP transmembrane-transporting ATPase activity
+is_a: GO:0001409 {is_inferred="true"} ! guanine nucleotide transmembrane transporter activity
+is_a: GO:0005346 {is_inferred="true"} ! purine ribonucleotide transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0043225 {is_inferred="true"} ! ATPase-coupled anion transmembrane transporter activity
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r38856 | paola | 2017-02-16 03:26:31 -0800 (Thu, 16 Feb 2017) | 3 lines

GH OBS: GO:0022405 ! hair cycle process and GO:0022404 ! molting cycle process #11123 - closed - see ticket for details

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38856)
+++ go_inferences.obo	(working copy)
@@ -44919,16 +44919,16 @@
 is_a: GO:0051791 {is_inferred="true"} ! medium-chain fatty acid metabolic process
 
 [Term]
-id: GO:0051794 ! regulation of catagen
+id: GO:0051794 ! regulation of timing of catagen
 is_a: GO:0048819 {is_inferred="true"} ! regulation of hair follicle maturation
 
 [Term]
-id: GO:0051795 ! positive regulation of catagen
-is_a: GO:0051794 {is_inferred="true"} ! regulation of catagen
+id: GO:0051795 ! positive regulation of timing of catagen
+is_a: GO:0051794 {is_inferred="true"} ! regulation of timing of catagen
 
 [Term]
-id: GO:0051796 ! negative regulation of catagen
-is_a: GO:0051794 {is_inferred="true"} ! regulation of catagen
+id: GO:0051796 ! negative regulation of timing of catagen
+is_a: GO:0051794 {is_inferred="true"} ! regulation of timing of catagen
 
 [Term]
 id: GO:0051797 ! regulation of hair follicle development
@@ -45019,28 +45019,28 @@
 is_a: GO:0051899 {is_inferred="true"} ! membrane depolarization
 
 [Term]
-id: GO:0051884 ! regulation of anagen
+id: GO:0051884 ! regulation of timing of anagen
 is_a: GO:0048819 {is_inferred="true"} ! regulation of hair follicle maturation
 
 [Term]
-id: GO:0051885 ! positive regulation of anagen
-is_a: GO:0051884 {is_inferred="true"} ! regulation of anagen
+id: GO:0051885 ! positive regulation of timing of anagen
+is_a: GO:0051884 {is_inferred="true"} ! regulation of timing of anagen
 
 [Term]
-id: GO:0051886 ! negative regulation of anagen
-is_a: GO:0051884 {is_inferred="true"} ! regulation of anagen
+id: GO:0051886 ! negative regulation of timing of anagen
+is_a: GO:0051884 {is_inferred="true"} ! regulation of timing of anagen
 
 [Term]
-id: GO:0051887 ! regulation of exogen
+id: GO:0051887 ! regulation of timing of exogen
 is_a: GO:0048819 {is_inferred="true"} ! regulation of hair follicle maturation
 
 [Term]
-id: GO:0051888 ! positive regulation of exogen
-is_a: GO:0051887 {is_inferred="true"} ! regulation of exogen
+id: GO:0051888 ! positive regulation of timing of exogen
+is_a: GO:0051887 {is_inferred="true"} ! regulation of timing of exogen
 
 [Term]
-id: GO:0051889 ! negative regulation of exogen
-is_a: GO:0051887 {is_inferred="true"} ! regulation of exogen
+id: GO:0051889 ! negative regulation of timing of exogen
+is_a: GO:0051887 {is_inferred="true"} ! regulation of timing of exogen
 
 [Term]
 id: GO:0051890 ! regulation of cardioblast differentiation
------------------------------------------------------------------------
r38854 | paola | 2017-02-16 00:17:16 -0800 (Thu, 16 Feb 2017) | 2 lines

GH sympathetic neuron projection extension/guidance #10445 - closed - added logical def to ‘sympathetic neuron axon guidance’ 

changes in entailments

------------------------------------------------------------------------
r38765 | mcourtot | 2017-02-15 04:56:48 -0800 (Wed, 15 Feb 2017) | 1 line

updated transcription antitermination definition to site(s) as per https://github.com/geneontology/go-ontology/issues/12178

changes in entailments

------------------------------------------------------------------------
r38760 | dph | 2017-02-14 09:34:24 -0800 (Tue, 14 Feb 2017) | 2 lines

Tweaked the definition of chaperone-mediated autophagy and added a clause to the logical definition that it has an input of a protein.

changes in entailments

------------------------------------------------------------------------
r38758 | mcourtot | 2017-02-14 06:32:40 -0800 (Tue, 14 Feb 2017) | 1 line

fixed namespace

changes in entailments

------------------------------------------------------------------------
r38746 | tberardi | 2017-02-13 16:17:14 -0800 (Mon, 13 Feb 2017) | 1 line

GH13019 missing parent to GO:0090539 peptide pheromone export by transmembrane transport - closed

changes in entailments

------------------------------------------------------------------------
r38746 | tberardi | 2017-02-13 16:17:14 -0800 (Mon, 13 Feb 2017) | 1 line

GH13019 missing parent to GO:0090539 peptide pheromone export by transmembrane transport - closed

changes in entailments

------------------------------------------------------------------------
r38744 | tberardi | 2017-02-13 16:08:18 -0800 (Mon, 13 Feb 2017) | 1 line

GH12984 new term Telomere maintenance via telomere trimming - closed again

changes in entailments

------------------------------------------------------------------------
r38742 | dph | 2017-02-13 06:39:18 -0800 (Mon, 13 Feb 2017) | 2 lines

Added some logical defs for the differentiation in phenotypic switching terms that hopefully clarifies them and allows for good inference. GH13010-closed.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38742)
+++ go_inferences.obo	(working copy)
@@ -57725,6 +57725,10 @@
 is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
 
 [Term]
+id: GO:0090679 ! cell differentiation involved in phenotypic switching
+is_a: GO:0030154 {is_inferred="true"} ! cell differentiation
+
+[Term]
 id: GO:0090688 ! cleavage furrow rim
 is_a: GO:0032155 {is_inferred="true"} ! cell division site part
 
@@ -87567,6 +87571,7 @@
 [Term]
 id: GO:1905420 ! vascular smooth muscle cell differentiation involved in phenotypic switching
 is_a: GO:0035886 {is_inferred="true"} ! vascular smooth muscle cell differentiation
+is_a: GO:0090679 {is_inferred="true"} ! cell differentiation involved in phenotypic switching
 
 [Term]
 id: GO:1905421 ! regulation of plant organ morphogenesis
@@ -90008,19 +90013,19 @@
 
 [Term]
 id: GO:1905930 ! regulation of vascular smooth muscle cell differentiation involved in phenotypic switching
-is_a: GO:1900239 {is_inferred="true"} ! regulation of phenotypic switching
 is_a: GO:1905063 {is_inferred="true"} ! regulation of vascular smooth muscle cell differentiation
+is_a: GO:1905915 {is_inferred="true"} ! regulation of cell differentiation involved in phenotypic switching
 
 [Term]
 id: GO:1905931 ! negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching
-is_a: GO:1900240 {is_inferred="true"} ! negative regulation of phenotypic switching
 is_a: GO:1905064 {is_inferred="true"} ! negative regulation of vascular smooth muscle cell differentiation
+is_a: GO:1905916 {is_inferred="true"} ! negative regulation of cell differentiation involved in phenotypic switching
 is_a: GO:1905930 {is_inferred="true"} ! regulation of vascular smooth muscle cell differentiation involved in phenotypic switching
 
 [Term]
 id: GO:1905932 ! positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching
-is_a: GO:1900241 {is_inferred="true"} ! positive regulation of phenotypic switching
 is_a: GO:1905065 {is_inferred="true"} ! positive regulation of vascular smooth muscle cell differentiation
+is_a: GO:1905917 {is_inferred="true"} ! positive regulation of cell differentiation involved in phenotypic switching
 is_a: GO:1905930 {is_inferred="true"} ! regulation of vascular smooth muscle cell differentiation involved in phenotypic switching
 
 [Term]
------------------------------------------------------------------------
r38740 | termgenie | 2017-02-13 06:11:05 -0800 (Mon, 13 Feb 2017) | 4 lines

TermGenie commit for user: BarbaraCzub reviewed by ukemi

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38740)
+++ go_inferences.obo	(working copy)
@@ -89930,6 +89930,23 @@
 is_a: GO:1905912 {is_inferred="true"} ! regulation of calcium ion export from cell
 
 [Term]
+id: GO:1905915 ! regulation of cell differentiation involved in phenotypic switching
+is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
+is_a: GO:1900239 {is_inferred="true"} ! regulation of phenotypic switching
+
+[Term]
+id: GO:1905916 ! negative regulation of cell differentiation involved in phenotypic switching
+is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
+is_a: GO:1900240 {is_inferred="true"} ! negative regulation of phenotypic switching
+is_a: GO:1905915 {is_inferred="true"} ! regulation of cell differentiation involved in phenotypic switching
+
+[Term]
+id: GO:1905917 ! positive regulation of cell differentiation involved in phenotypic switching
+is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
+is_a: GO:1900241 {is_inferred="true"} ! positive regulation of phenotypic switching
+is_a: GO:1905915 {is_inferred="true"} ! regulation of cell differentiation involved in phenotypic switching
+
+[Term]
 id: GO:1905918 ! regulation of CoA-transferase activity
 is_a: GO:0051338 {is_inferred="true"} ! regulation of transferase activity
 
@@ -89990,6 +90007,23 @@
 is_a: GO:1905927 {is_inferred="true"} ! regulation of invadopodium disassembly
 
 [Term]
+id: GO:1905930 ! regulation of vascular smooth muscle cell differentiation involved in phenotypic switching
+is_a: GO:1900239 {is_inferred="true"} ! regulation of phenotypic switching
+is_a: GO:1905063 {is_inferred="true"} ! regulation of vascular smooth muscle cell differentiation
+
+[Term]
+id: GO:1905931 ! negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching
+is_a: GO:1900240 {is_inferred="true"} ! negative regulation of phenotypic switching
+is_a: GO:1905064 {is_inferred="true"} ! negative regulation of vascular smooth muscle cell differentiation
+is_a: GO:1905930 {is_inferred="true"} ! regulation of vascular smooth muscle cell differentiation involved in phenotypic switching
+
+[Term]
+id: GO:1905932 ! positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching
+is_a: GO:1900241 {is_inferred="true"} ! positive regulation of phenotypic switching
+is_a: GO:1905065 {is_inferred="true"} ! positive regulation of vascular smooth muscle cell differentiation
+is_a: GO:1905930 {is_inferred="true"} ! regulation of vascular smooth muscle cell differentiation involved in phenotypic switching
+
+[Term]
 id: GO:1905933 ! regulation of cell fate determination
 is_a: GO:0010453 {is_inferred="true"} ! regulation of cell fate commitment
 
@@ -90004,6 +90038,76 @@
 is_a: GO:1905933 {is_inferred="true"} ! regulation of cell fate determination
 
 [Term]
+id: GO:1905936 ! regulation of germ cell proliferation
+is_a: GO:0042127 {is_inferred="true"} ! regulation of cell proliferation
+is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
+is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
+is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
+
+[Term]
+id: GO:1905937 ! negative regulation of germ cell proliferation
+is_a: GO:0008285 {is_inferred="true"} ! negative regulation of cell proliferation
+is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
+is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
+is_a: GO:1905936 {is_inferred="true"} ! regulation of germ cell proliferation
+is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
+
+[Term]
+id: GO:1905938 ! positive regulation of germ cell proliferation
+is_a: GO:0008284 {is_inferred="true"} ! positive regulation of cell proliferation
+is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
+is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
+is_a: GO:1905936 {is_inferred="true"} ! regulation of germ cell proliferation
+is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
+
+[Term]
+id: GO:1905939 ! regulation of gonad development
+is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
+is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
+
+[Term]
+id: GO:1905940 ! negative regulation of gonad development
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
+is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
+is_a: GO:1905939 {is_inferred="true"} ! regulation of gonad development
+is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
+
+[Term]
+id: GO:1905941 ! positive regulation of gonad development
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
+is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
+is_a: GO:1905939 {is_inferred="true"} ! regulation of gonad development
+is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
+
+[Term]
+id: GO:1905942 ! regulation of formation of growth cone in injured axon
+is_a: GO:0048686 {is_inferred="true"} ! regulation of sprouting of injured axon
+
+[Term]
+id: GO:1905943 ! negative regulation of formation of growth cone in injured axon
+is_a: GO:0048688 {is_inferred="true"} ! negative regulation of sprouting of injured axon
+is_a: GO:1905942 {is_inferred="true"} ! regulation of formation of growth cone in injured axon
+
+[Term]
+id: GO:1905944 ! positive regulation of formation of growth cone in injured axon
+is_a: GO:0048687 {is_inferred="true"} ! positive regulation of sprouting of injured axon
+is_a: GO:1905942 {is_inferred="true"} ! regulation of formation of growth cone in injured axon
+
+[Term]
+id: GO:1905945 ! regulation of response to calcium ion
+is_a: GO:0048583 {is_inferred="true"} ! regulation of response to stimulus
+
+[Term]
+id: GO:1905946 ! negative regulation of response to calcium ion
+is_a: GO:0048585 {is_inferred="true"} ! negative regulation of response to stimulus
+is_a: GO:1905945 {is_inferred="true"} ! regulation of response to calcium ion
+
+[Term]
+id: GO:1905947 ! positive regulation of response to calcium ion
+is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
+is_a: GO:1905945 {is_inferred="true"} ! regulation of response to calcium ion
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
@@ -91129,22 +91233,17 @@
 
 [Term]
 id: GO:2000018 ! regulation of male gonad development
-is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
-is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
+is_a: GO:1905939 {is_inferred="true"} ! regulation of gonad development
 
 [Term]
 id: GO:2000019 ! negative regulation of male gonad development
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
+is_a: GO:1905940 {is_inferred="true"} ! negative regulation of gonad development
 is_a: GO:2000018 {is_inferred="true"} ! regulation of male gonad development
-is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
 
 [Term]
 id: GO:2000020 ! positive regulation of male gonad development
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
+is_a: GO:1905941 {is_inferred="true"} ! positive regulation of gonad development
 is_a: GO:2000018 {is_inferred="true"} ! regulation of male gonad development
-is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
 
 [Term]
 id: GO:2000022 ! regulation of jasmonic acid mediated signaling pathway
@@ -91968,6 +92067,18 @@
 is_a: GO:2000191 {is_inferred="true"} ! regulation of fatty acid transport
 
 [Term]
+id: GO:2000194 ! regulation of female gonad development
+is_a: GO:1905939 {is_inferred="true"} ! regulation of gonad development
+
+[Term]
+id: GO:2000195 ! negative regulation of female gonad development
+is_a: GO:1905940 {is_inferred="true"} ! negative regulation of gonad development
+
+[Term]
+id: GO:2000196 ! positive regulation of female gonad development
+is_a: GO:1905941 {is_inferred="true"} ! positive regulation of gonad development
+
+[Term]
 id: GO:2000197 ! regulation of ribonucleoprotein complex localization
 is_a: GO:0060341 {is_inferred="true"} ! regulation of cellular localization
 
@@ -92240,23 +92351,16 @@
 
 [Term]
 id: GO:2000254 ! regulation of male germ cell proliferation
-is_a: GO:0042127 {is_inferred="true"} ! regulation of cell proliferation
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
-is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
-is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
+is_a: GO:1905936 {is_inferred="true"} ! regulation of germ cell proliferation
 
 [Term]
 id: GO:2000255 ! negative regulation of male germ cell proliferation
-is_a: GO:0008285 {is_inferred="true"} ! negative regulation of cell proliferation
-is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
+is_a: GO:1905937 {is_inferred="true"} ! negative regulation of germ cell proliferation
 is_a: GO:2000254 {is_inferred="true"} ! regulation of male germ cell proliferation
 
 [Term]
 id: GO:2000256 ! positive regulation of male germ cell proliferation
-is_a: GO:0008284 {is_inferred="true"} ! positive regulation of cell proliferation
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
+is_a: GO:1905938 {is_inferred="true"} ! positive regulation of germ cell proliferation
 is_a: GO:2000254 {is_inferred="true"} ! regulation of male germ cell proliferation
 
 [Term]
------------------------------------------------------------------------
r38733 | paola | 2017-02-13 04:02:06 -0800 (Mon, 13 Feb 2017) | 2 lines

Fixed typo in def. comment of 'axoneme'

changes in entailments

------------------------------------------------------------------------
r38699 | tberardi | 2017-02-10 15:20:27 -0800 (Fri, 10 Feb 2017) | 1 line

GH12886 TPV protein import into nucleus, docking - closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38699)
+++ go_inferences.obo	(working copy)
@@ -1650,7 +1650,7 @@
 
 [Term]
 id: GO:0001893 ! maternal placenta development
-is_a: GO:0048608 {is_inferred="true"} ! reproductive structure development
+is_a: GO:0003006 {is_inferred="true"} ! developmental process involved in reproduction
 
 [Term]
 id: GO:0001898 ! regulation of cytolysis by symbiont of host cells
@@ -4104,18 +4104,10 @@
 is_a: GO:2000027 {is_inferred="true"} ! regulation of organ morphogenesis
 
 [Term]
-id: GO:0003157 ! endocardium development
-is_a: GO:0003158 {is_inferred="true"} ! endothelium development
-
-[Term]
 id: GO:0003158 ! endothelium development
 is_a: GO:0060429 {is_inferred="true"} ! epithelium development
 
 [Term]
-id: GO:0003160 ! endocardium morphogenesis
-is_a: GO:0003159 {is_inferred="true"} ! morphogenesis of an endothelium
-
-[Term]
 id: GO:0003161 ! cardiac conduction system development
 is_a: GO:0048738 {is_inferred="true"} ! cardiac muscle tissue development
 
@@ -21010,6 +21002,10 @@
 is_a: GO:0010927 {is_inferred="true"} ! cellular component assembly involved in morphogenesis
 
 [Term]
+id: GO:0030916 ! otic vesicle formation
+is_a: GO:0072175 {is_inferred="true"} ! epithelial tube formation
+
+[Term]
 id: GO:0030932 ! amyloplast ADPG pyrophosphorylase complex
 is_a: GO:0031009 {is_inferred="true"} ! plastid ADPG pyrophosphorylase complex
 
@@ -52785,11 +52781,12 @@
 
 [Term]
 id: GO:0071599 ! otic vesicle development
+is_a: GO:0035295 {is_inferred="true"} ! tube development
 is_a: GO:0060429 {is_inferred="true"} ! epithelium development
 
 [Term]
 id: GO:0071600 ! otic vesicle morphogenesis
-is_a: GO:0002009 {is_inferred="true"} ! morphogenesis of an epithelium
+is_a: GO:0060562 {is_inferred="true"} ! epithelial tube morphogenesis
 
 [Term]
 id: GO:0071602 ! phytosphingosine biosynthetic process
@@ -97827,10 +97824,6 @@
 is_a: CHEBI:36080 {is_inferred="true"} ! protein
 
 [Term]
-id: PR:000007499 ! fibroblast growth factor 8
-is_a: CHEBI:36080 {is_inferred="true"} ! protein
-
-[Term]
 id: PR:000007555 ! filamin-A
 is_a: CHEBI:36080 {is_inferred="true"} ! protein
 
@@ -97847,10 +97840,6 @@
 is_a: CHEBI:36080 {is_inferred="true"} ! protein
 
 [Term]
-id: PR:000007636 ! forkhead box protein N1
-is_a: CHEBI:36080 {is_inferred="true"} ! protein
-
-[Term]
 id: PR:000007806 ! galanin
 is_a: CHEBI:36080 {is_inferred="true"} ! protein
 
@@ -98079,18 +98068,10 @@
 is_a: CHEBI:36080 {is_inferred="true"} ! protein
 
 [Term]
-id: PR:000014841 ! sonic hedgehog protein
-is_a: CHEBI:36080 {is_inferred="true"} ! protein
-
-[Term]
 id: PR:000015288 ! smoothened
 is_a: CHEBI:36080 {is_inferred="true"} ! protein
 
 [Term]
-id: PR:000015557 ! spondin-1
-is_a: CHEBI:36080 {is_inferred="true"} ! protein
-
-[Term]
 id: PR:000015794 ! syntaxin-2
 is_a: CHEBI:36080 {is_inferred="true"} ! protein
 
@@ -98219,38 +98200,10 @@
 is_a: CHEBI:33699 {is_inferred="true"} ! messenger RNA
 
 [Term]
-id: UBERON:0001289 ! descending limb of loop of Henle
-is_a: UBERON:0004810 {is_inferred="true"} ! nephron tubule epithelium
-
-[Term]
 id: UBERON:0003261 ! thyroid primordium endoderm
 is_a: UBERON:0004119 {is_inferred="true"} ! endoderm-derived structure
 
 [Term]
-id: UBERON:0004134 ! proximal tubule
-is_a: UBERON:0004810 {is_inferred="true"} ! nephron tubule epithelium
-
-[Term]
-id: UBERON:0004136 ! intermediate tubule
-is_a: UBERON:0004810 {is_inferred="true"} ! nephron tubule epithelium
-
-[Term]
-id: UBERON:0005130 ! metanephric loop of Henle
-is_a: UBERON:0004810 {is_inferred="true"} ! nephron tubule epithelium
-
-[Term]
-id: UBERON:0005164 ! ascending limb of loop of Henle
-is_a: UBERON:0004810 {is_inferred="true"} ! nephron tubule epithelium
-
-[Term]
-id: UBERON:0005421 ! pectoral appendage apical ectodermal ridge
-is_a: UBERON:0004121 {is_inferred="true"} ! ectoderm-derived structure
-
-[Term]
-id: UBERON:0005422 ! pelvic appendage apical ectodermal ridge
-is_a: UBERON:0004121 {is_inferred="true"} ! ectoderm-derived structure
-
-[Term]
 id: UBERON:0005721 ! pronephric mesoderm
 is_a: UBERON:0004120 {is_inferred="true"} ! mesoderm-derived structure
 
------------------------------------------------------------------------
r38694 | dph | 2017-02-10 10:45:21 -0800 (Fri, 10 Feb 2017) | 2 lines

Asserted chemical classifications for estrogen and androgen.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38694)
+++ go_inferences.obo	(working copy)
@@ -8505,6 +8505,14 @@
 is_a: GO:0008207 {is_inferred="true"} ! C21-steroid hormone metabolic process
 
 [Term]
+id: GO:0008209 ! androgen metabolic process
+is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
+
+[Term]
+id: GO:0008210 ! estrogen metabolic process
+is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
+
+[Term]
 id: GO:0008215 ! spermine metabolic process
 is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 
@@ -81040,14 +81048,17 @@
 [Term]
 id: GO:1904076 ! regulation of estrogen biosynthetic process
 is_a: GO:0046885 {is_inferred="true"} ! regulation of hormone biosynthetic process
+is_a: GO:0050810 {is_inferred="true"} ! regulation of steroid biosynthetic process
 
 [Term]
 id: GO:1904077 ! negative regulation of estrogen biosynthetic process
+is_a: GO:0010894 {is_inferred="true"} ! negative regulation of steroid biosynthetic process
 is_a: GO:0032353 {is_inferred="true"} ! negative regulation of hormone biosynthetic process
 is_a: GO:1904076 {is_inferred="true"} ! regulation of estrogen biosynthetic process
 
 [Term]
 id: GO:1904078 ! positive regulation of estrogen biosynthetic process
+is_a: GO:0010893 {is_inferred="true"} ! positive regulation of steroid biosynthetic process
 is_a: GO:0046886 {is_inferred="true"} ! positive regulation of hormone biosynthetic process
 is_a: GO:1904076 {is_inferred="true"} ! regulation of estrogen biosynthetic process
 
@@ -91894,6 +91905,7 @@
 
 [Term]
 id: GO:2000180 ! negative regulation of androgen biosynthetic process
+is_a: GO:0010894 {is_inferred="true"} ! negative regulation of steroid biosynthetic process
 is_a: GO:0032353 {is_inferred="true"} ! negative regulation of hormone biosynthetic process
 
 [Term]
------------------------------------------------------------------------
r38692 | dph | 2017-02-10 10:19:37 -0800 (Fri, 10 Feb 2017) | 2 lines

Fixed bad PMID.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38692)
+++ go_inferences.obo	(working copy)
@@ -49310,6 +49310,17 @@
 is_a: GO:0061847 {is_inferred="true"} ! response to cholecystokinin
 
 [Term]
+id: GO:0061850 ! growth cone leading edge
+is_a: GO:0031252 {is_inferred="true"} ! cell leading edge
+is_a: GO:0044463 {is_inferred="true"} ! cell projection part
+is_a: GO:0097458 {is_inferred="true"} ! neuron part
+
+[Term]
+id: GO:0061851 ! leading edge of lamellipodium
+is_a: GO:0031252 {is_inferred="true"} ! cell leading edge
+is_a: GO:0044463 {is_inferred="true"} ! cell projection part
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
------------------------------------------------------------------------
r38689 | dph | 2017-02-10 08:40:51 -0800 (Fri, 10 Feb 2017) | 2 lines

Lots of edits to the ERAD pathway and associated terms. GH12912-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38689)
+++ go_inferences.obo	(working copy)
@@ -58275,7 +58275,7 @@
 is_a: GO:0098659 {is_inferred="true"} ! inorganic cation import into cell
 
 [Term]
-id: GO:0097466 ! glycoprotein ERAD pathway
+id: GO:0097466 ! ubiquitin-dependent glycoprotein ERAD pathway
 is_a: GO:1904587 {is_inferred="true"} ! response to glycoprotein
 
 [Term]
------------------------------------------------------------------------
r38687 | dph | 2017-02-10 04:15:23 -0800 (Fri, 10 Feb 2017) | 2 lines

GH1300-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38687)
+++ go_inferences.obo	(working copy)
@@ -22144,6 +22144,7 @@
 
 [Term]
 id: GO:0031569 ! G2 cell size control checkpoint
+is_a: GO:0010972 {is_inferred="true"} ! negative regulation of G2/M transition of mitotic cell cycle
 is_a: GO:0031567 {is_inferred="true"} ! mitotic cell size control checkpoint
 
 [Term]
------------------------------------------------------------------------
r38682 | tberardi | 2017-02-09 17:23:33 -0800 (Thu, 09 Feb 2017) | 1 line

GH12991 mRNA metabolism parent? - closed again

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38682)
+++ go_inferences.obo	(working copy)
@@ -48094,6 +48094,7 @@
 
 [Term]
 id: GO:0061013 ! regulation of mRNA catabolic process
+is_a: GO:0010468 {is_inferred="true"} ! regulation of gene expression
 is_a: GO:0031329 {is_inferred="true"} ! regulation of cellular catabolic process
 is_a: GO:1903311 {is_inferred="true"} ! regulation of mRNA metabolic process
 
@@ -73074,6 +73075,7 @@
 
 [Term]
 id: GO:1902373 ! negative regulation of mRNA catabolic process
+is_a: GO:0010628 {is_inferred="true"} ! positive regulation of gene expression
 is_a: GO:0061013 {is_inferred="true"} ! regulation of mRNA catabolic process
 is_a: GO:1902369 {is_inferred="true"} ! negative regulation of RNA catabolic process
 is_a: GO:1903312 {is_inferred="true"} ! negative regulation of mRNA metabolic process
------------------------------------------------------------------------
r38673 | paola | 2017-02-09 07:49:30 -0800 (Thu, 09 Feb 2017) | 3 lines

GH NTR: vasodilation by nitric oxide #12253 - work in progress

changes in entailments

------------------------------------------------------------------------
r38668 | dph | 2017-02-09 06:05:30 -0800 (Thu, 09 Feb 2017) | 2 lines

GH13005-closed

changes in entailments

------------------------------------------------------------------------
r38668 | dph | 2017-02-09 06:05:30 -0800 (Thu, 09 Feb 2017) | 2 lines

GH13005-closed

changes in entailments

------------------------------------------------------------------------
r38666 | dph | 2017-02-09 05:38:07 -0800 (Thu, 09 Feb 2017) | 2 lines

GH13007-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38666)
+++ go_inferences.obo	(working copy)
@@ -49319,6 +49319,10 @@
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
 
 [Term]
+id: GO:0061848 ! cellular response to cholecystokinin
+is_a: GO:0061847 {is_inferred="true"} ! response to cholecystokinin
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
------------------------------------------------------------------------
r38664 | termgenie | 2017-02-09 04:17:44 -0800 (Thu, 09 Feb 2017) | 4 lines

TermGenie commit for user: bmeldal reviewed by ukemi

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38664)
+++ go_inferences.obo	(working copy)
@@ -41455,20 +41455,20 @@
 
 [Term]
 id: GO:0048334 ! regulation of mesodermal cell fate determination
-is_a: GO:0010453 {is_inferred="true"} ! regulation of cell fate commitment
 is_a: GO:1905770 {is_inferred="true"} ! regulation of mesodermal cell differentiation
+is_a: GO:1905933 {is_inferred="true"} ! regulation of cell fate determination
 
 [Term]
 id: GO:0048335 ! negative regulation of mesodermal cell fate determination
-is_a: GO:0010454 {is_inferred="true"} ! negative regulation of cell fate commitment
 is_a: GO:0048334 {is_inferred="true"} ! regulation of mesodermal cell fate determination
 is_a: GO:1905771 {is_inferred="true"} ! negative regulation of mesodermal cell differentiation
+is_a: GO:1905934 {is_inferred="true"} ! negative regulation of cell fate determination
 
 [Term]
 id: GO:0048336 ! positive regulation of mesodermal cell fate determination
-is_a: GO:0010455 {is_inferred="true"} ! positive regulation of cell fate commitment
 is_a: GO:0048334 {is_inferred="true"} ! regulation of mesodermal cell fate determination
 is_a: GO:1905772 {is_inferred="true"} ! positive regulation of mesodermal cell differentiation
+is_a: GO:1905935 {is_inferred="true"} ! positive regulation of cell fate determination
 
 [Term]
 id: GO:0048337 ! positive regulation of mesodermal cell fate specification
@@ -84472,18 +84472,18 @@
 
 [Term]
 id: GO:1904785 ! regulation of asymmetric protein localization involved in cell fate determination
-is_a: GO:0010453 {is_inferred="true"} ! regulation of cell fate commitment
 is_a: GO:0032880 {is_inferred="true"} ! regulation of protein localization
+is_a: GO:1905933 {is_inferred="true"} ! regulation of cell fate determination
 
 [Term]
 id: GO:1904786 ! negative regulation of asymmetric protein localization involved in cell fate determination
-is_a: GO:0010454 {is_inferred="true"} ! negative regulation of cell fate commitment
 is_a: GO:1904785 {is_inferred="true"} ! regulation of asymmetric protein localization involved in cell fate determination
+is_a: GO:1905934 {is_inferred="true"} ! negative regulation of cell fate determination
 
 [Term]
 id: GO:1904787 ! positive regulation of asymmetric protein localization involved in cell fate determination
-is_a: GO:0010455 {is_inferred="true"} ! positive regulation of cell fate commitment
 is_a: GO:1904785 {is_inferred="true"} ! regulation of asymmetric protein localization involved in cell fate determination
+is_a: GO:1905935 {is_inferred="true"} ! positive regulation of cell fate determination
 
 [Term]
 id: GO:1904788 ! positive regulation of induction of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter
@@ -89919,6 +89919,80 @@
 is_a: GO:1905912 {is_inferred="true"} ! regulation of calcium ion export from cell
 
 [Term]
+id: GO:1905918 ! regulation of CoA-transferase activity
+is_a: GO:0051338 {is_inferred="true"} ! regulation of transferase activity
+
+[Term]
+id: GO:1905919 ! negative regulation of CoA-transferase activity
+is_a: GO:0051348 {is_inferred="true"} ! negative regulation of transferase activity
+is_a: GO:1905918 {is_inferred="true"} ! regulation of CoA-transferase activity
+
+[Term]
+id: GO:1905920 ! positive regulation of CoA-transferase activity
+is_a: GO:0051347 {is_inferred="true"} ! positive regulation of transferase activity
+is_a: GO:1905918 {is_inferred="true"} ! regulation of CoA-transferase activity
+
+[Term]
+id: GO:1905921 ! regulation of acetylcholine biosynthetic process
+is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
+is_a: GO:0060408 {is_inferred="true"} ! regulation of acetylcholine metabolic process
+
+[Term]
+id: GO:1905922 ! negative regulation of acetylcholine biosynthetic process
+is_a: GO:0031327 {is_inferred="true"} ! negative regulation of cellular biosynthetic process
+is_a: GO:0060410 {is_inferred="true"} ! negative regulation of acetylcholine metabolic process
+is_a: GO:1905921 {is_inferred="true"} ! regulation of acetylcholine biosynthetic process
+
+[Term]
+id: GO:1905923 ! positive regulation of acetylcholine biosynthetic process
+is_a: GO:0031328 {is_inferred="true"} ! positive regulation of cellular biosynthetic process
+is_a: GO:0060409 {is_inferred="true"} ! positive regulation of acetylcholine metabolic process
+is_a: GO:1905921 {is_inferred="true"} ! regulation of acetylcholine biosynthetic process
+
+[Term]
+id: GO:1905924 ! regulation of invadopodium assembly
+is_a: GO:0060491 {is_inferred="true"} ! regulation of cell projection assembly
+
+[Term]
+id: GO:1905925 ! negative regulation of invadopodium assembly
+is_a: GO:0031345 {is_inferred="true"} ! negative regulation of cell projection organization
+is_a: GO:1905924 {is_inferred="true"} ! regulation of invadopodium assembly
+
+[Term]
+id: GO:1905926 ! positive regulation of invadopodium assembly
+is_a: GO:0031346 {is_inferred="true"} ! positive regulation of cell projection organization
+is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
+is_a: GO:1905924 {is_inferred="true"} ! regulation of invadopodium assembly
+
+[Term]
+id: GO:1905927 ! regulation of invadopodium disassembly
+is_a: GO:0031344 {is_inferred="true"} ! regulation of cell projection organization
+
+[Term]
+id: GO:1905928 ! negative regulation of invadopodium disassembly
+is_a: GO:0031345 {is_inferred="true"} ! negative regulation of cell projection organization
+is_a: GO:1905927 {is_inferred="true"} ! regulation of invadopodium disassembly
+
+[Term]
+id: GO:1905929 ! positive regulation of invadopodium disassembly
+is_a: GO:0031346 {is_inferred="true"} ! positive regulation of cell projection organization
+is_a: GO:1905927 {is_inferred="true"} ! regulation of invadopodium disassembly
+
+[Term]
+id: GO:1905933 ! regulation of cell fate determination
+is_a: GO:0010453 {is_inferred="true"} ! regulation of cell fate commitment
+
+[Term]
+id: GO:1905934 ! negative regulation of cell fate determination
+is_a: GO:0010454 {is_inferred="true"} ! negative regulation of cell fate commitment
+is_a: GO:1905933 {is_inferred="true"} ! regulation of cell fate determination
+
+[Term]
+id: GO:1905935 ! positive regulation of cell fate determination
+is_a: GO:0010455 {is_inferred="true"} ! positive regulation of cell fate commitment
+is_a: GO:1905933 {is_inferred="true"} ! regulation of cell fate determination
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r38658 | hjd | 2017-02-08 14:07:47 -0800 (Wed, 08 Feb 2017) | 2 lines

retyped in def by hand

changes in entailments

------------------------------------------------------------------------
r38653 | davidos | 2017-02-08 08:54:09 -0800 (Wed, 08 Feb 2017) | 1 line

More global change of pattern for regulation of biological process. Diff is pretty huge. Expecting new inferences to result (although none happened in last commit!) see https://github.com/geneontology/go-ontology/issues/13006.

changes in entailments

------------------------------------------------------------------------
r38651 | davidos | 2017-02-08 08:24:29 -0800 (Wed, 08 Feb 2017) | 1 line

Global change of pattern for regulation of biological process. Diff is pretty huge. Expecting new inferences to result. see https://github.com/geneontology/go-ontology/issues/13006.

changes in entailments

------------------------------------------------------------------------
r38649 | paola | 2017-02-08 07:40:13 -0800 (Wed, 08 Feb 2017) | 2 lines

GH NTR: vasodilation by nitric oxide #12253 - more work

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38649)
+++ go_inferences.obo	(working copy)
@@ -37689,6 +37689,7 @@
 [Term]
 id: GO:0045906 ! negative regulation of vasoconstriction
 is_a: GO:0019229 {is_inferred="true"} ! regulation of vasoconstriction
+is_a: GO:0097755 {is_inferred="true"} ! positive regulation of blood vessel diameter
 is_a: GO:1903523 {is_inferred="true"} ! negative regulation of blood circulation
 
 [Term]
------------------------------------------------------------------------
r38647 | paola | 2017-02-08 07:15:06 -0800 (Wed, 08 Feb 2017) | 2 lines

GH NTR: vasodilation by nitric oxide #12253 - work in progress 

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38647)
+++ go_inferences.obo	(working copy)
@@ -88689,25 +88689,6 @@
 is_a: GO:1905654 {is_inferred="true"} ! regulation of artery smooth muscle contraction
 
 [Term]
-id: GO:1905657 ! regulation of relaxation of vascular smooth muscle
-is_a: GO:0006940 {is_inferred="true"} ! regulation of smooth muscle contraction
-is_a: GO:0042312 {is_inferred="true"} ! regulation of vasodilation
-is_a: GO:1901080 {is_inferred="true"} ! regulation of relaxation of smooth muscle
-
-[Term]
-id: GO:1905658 ! negative regulation of relaxation of vascular smooth muscle
-is_a: GO:0045908 {is_inferred="true"} ! negative regulation of vasodilation
-is_a: GO:0045987 {is_inferred="true"} ! positive regulation of smooth muscle contraction
-is_a: GO:1901081 {is_inferred="true"} ! negative regulation of relaxation of smooth muscle
-is_a: GO:1905657 {is_inferred="true"} ! regulation of relaxation of vascular smooth muscle
-
-[Term]
-id: GO:1905659 ! positive regulation of relaxation of vascular smooth muscle
-is_a: GO:0045909 {is_inferred="true"} ! positive regulation of vasodilation
-is_a: GO:1901082 {is_inferred="true"} ! positive regulation of relaxation of smooth muscle
-is_a: GO:1905657 {is_inferred="true"} ! regulation of relaxation of vascular smooth muscle
-
-[Term]
 id: GO:1905660 ! mitotic checkpoint complex assembly
 is_a: GO:0006461 {is_inferred="true"} ! protein complex assembly
 
------------------------------------------------------------------------
r38643 | paola | 2017-02-08 06:45:10 -0800 (Wed, 08 Feb 2017) | 2 lines

GH NTR: vasodilation by nitric oxide #12253 - work in progress

changes in entailments

------------------------------------------------------------------------
r38641 | mcourtot | 2017-02-08 06:06:44 -0800 (Wed, 08 Feb 2017) | 1 line

modified lactation. Closes #12382

changes in entailments

------------------------------------------------------------------------
r38635 | paola | 2017-02-08 02:42:32 -0800 (Wed, 08 Feb 2017) | 2 lines

GH NTR: vasodilation by nitric oxide #12253 - work in progress

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38635)
+++ go_inferences.obo	(working copy)
@@ -34817,7 +34817,7 @@
 is_a: GO:1902562 {is_inferred="true"} ! H4 histone acetyltransferase complex
 
 [Term]
-id: GO:0044552 ! modulation of vasodilation in other organism
+id: GO:0044552 ! vasodilation in other organism
 is_a: GO:0044706 {is_inferred="true"} ! multi-multicellular organism process
 
 [Term]
------------------------------------------------------------------------
r38632 | tberardi | 2017-02-07 17:03:47 -0800 (Tue, 07 Feb 2017) | 1 line

GH12984 new term Telomere maintenance via telomere trimming  - closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38632)
+++ go_inferences.obo	(working copy)
@@ -82730,6 +82730,7 @@
 [Term]
 id: GO:1904429 ! regulation of t-circle formation
 is_a: GO:0032204 {is_inferred="true"} ! regulation of telomere maintenance
+is_a: GO:0044087 {is_inferred="true"} ! regulation of cellular component biogenesis
 
 [Term]
 id: GO:1904430 ! negative regulation of t-circle formation
@@ -82739,6 +82740,7 @@
 [Term]
 id: GO:1904431 ! positive regulation of t-circle formation
 is_a: GO:0032206 {is_inferred="true"} ! positive regulation of telomere maintenance
+is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
 is_a: GO:1904429 {is_inferred="true"} ! regulation of t-circle formation
 
 [Term]
------------------------------------------------------------------------
r38630 | tberardi | 2017-02-07 11:41:43 -0800 (Tue, 07 Feb 2017) | 1 line

GH12980 NTR: replication fork processing at tRNA genes - closed

changes in entailments

------------------------------------------------------------------------
r38628 | termgenie | 2017-02-07 07:44:26 -0800 (Tue, 07 Feb 2017) | 4 lines

TermGenie commit for user: rachhuntley reviewed by ukemi

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38628)
+++ go_inferences.obo	(working copy)
@@ -89907,6 +89907,34 @@
 is_a: GO:1905906 {is_inferred="true"} ! regulation of amyloid fibril formation
 
 [Term]
+id: GO:1905909 ! regulation of dauer entry
+is_a: GO:0061065 {is_inferred="true"} ! regulation of dauer larval development
+
+[Term]
+id: GO:1905910 ! negative regulation of dauer entry
+is_a: GO:0061067 {is_inferred="true"} ! negative regulation of dauer larval development
+is_a: GO:1905909 {is_inferred="true"} ! regulation of dauer entry
+
+[Term]
+id: GO:1905911 ! positive regulation of dauer entry
+is_a: GO:0061066 {is_inferred="true"} ! positive regulation of dauer larval development
+is_a: GO:1905909 {is_inferred="true"} ! regulation of dauer entry
+
+[Term]
+id: GO:1905912 ! regulation of calcium ion export from cell
+is_a: GO:0051924 {is_inferred="true"} ! regulation of calcium ion transport
+
+[Term]
+id: GO:1905913 ! negative regulation of calcium ion export from cell
+is_a: GO:0051926 {is_inferred="true"} ! negative regulation of calcium ion transport
+is_a: GO:1905912 {is_inferred="true"} ! regulation of calcium ion export from cell
+
+[Term]
+id: GO:1905914 ! positive regulation of calcium ion export from cell
+is_a: GO:0051928 {is_inferred="true"} ! positive regulation of calcium ion transport
+is_a: GO:1905912 {is_inferred="true"} ! regulation of calcium ion export from cell
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r38625 | hjd | 2017-02-07 07:31:01 -0800 (Tue, 07 Feb 2017) | 2 lines

drat that punctuation

changes in entailments

------------------------------------------------------------------------
r38612 | tberardi | 2017-02-06 17:38:46 -0800 (Mon, 06 Feb 2017) | 1 line

GH12990 Creation of MATH domain binding and addition of synonym - closed

changes in entailments

------------------------------------------------------------------------
r38609 | tberardi | 2017-02-06 17:02:55 -0800 (Mon, 06 Feb 2017) | 1 line

GH12991 mRNA metabolism parent? - closed

changes in entailments

------------------------------------------------------------------------
r38608 | tberardi | 2017-02-06 16:57:33 -0800 (Mon, 06 Feb 2017) | 1 line

GH12987 NTR DNA repair complex assembly - closed

changes in entailments

------------------------------------------------------------------------
r38602 | davidos | 2017-02-06 06:00:17 -0800 (Mon, 06 Feb 2017) | 1 line

fixed error linking pr ribbon synapse to compound eye pr

changes in entailments

------------------------------------------------------------------------
r38600 | dph | 2017-02-06 05:46:14 -0800 (Mon, 06 Feb 2017) | 2 lines

Relaxed taxon constriction for ovulation cycle process. GH12997-closed

changes in entailments

------------------------------------------------------------------------
r38598 | mcourtot | 2017-02-06 05:35:55 -0800 (Mon, 06 Feb 2017) | 1 line

closes #12533, redefine GO:0061487, DNA replication initiation from late origin, logically adding a restriction 'has participant some late origin'.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38598)
+++ go_inferences.obo	(working copy)
@@ -48955,6 +48955,10 @@
 is_a: GO:0042493 {is_inferred="true"} ! response to drug
 
 [Term]
+id: GO:0061487 ! DNA replication initiation from late origin
+is_a: GO:0006270 {is_inferred="true"} ! DNA replication initiation
+
+[Term]
 id: GO:0061488 ! adenine import into cell
 is_a: GO:0015853 {is_inferred="true"} ! adenine transport
 is_a: GO:0098657 {is_inferred="true"} ! import into cell
------------------------------------------------------------------------
r38596 | dph | 2017-02-06 05:26:10 -0800 (Mon, 06 Feb 2017) | 2 lines

GH12865-closed. Removed regulation of immune and defense response parents from organism interaction terms.

changes in entailments

------------------------------------------------------------------------
r38594 | dph | 2017-02-06 05:17:22 -0800 (Mon, 06 Feb 2017) | 2 lines

Made autophagy and children types of catabolic processes. Also removed several asserted parents since they are now inferred by the reasoner. GH12943-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38594)
+++ go_inferences.obo	(working copy)
@@ -699,6 +699,26 @@
 is_a: GO:0031062 {is_inferred="true"} ! positive regulation of histone methylation
 
 [Term]
+id: GO:0000422 ! mitophagy
+is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
+
+[Term]
+id: GO:0000423 ! macromitophagy
+is_a: GO:0000422 {is_inferred="true"} ! mitophagy
+
+[Term]
+id: GO:0000424 ! microautophagy of mitochondrion
+is_a: GO:0000422 {is_inferred="true"} ! mitophagy
+
+[Term]
+id: GO:0000425 ! macropexophagy
+is_a: GO:0030242 {is_inferred="true"} ! pexophagy
+
+[Term]
+id: GO:0000426 ! micropexophagy
+is_a: GO:0030242 {is_inferred="true"} ! pexophagy
+
+[Term]
 id: GO:0000427 ! plastid-encoded plastid RNA polymerase complex
 is_a: GO:0000428 {is_inferred="true"} ! DNA-directed RNA polymerase complex
 is_a: GO:0044435 {is_inferred="true"} ! plastid part
@@ -11676,17 +11696,17 @@
 
 [Term]
 id: GO:0010506 ! regulation of autophagy
-is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
+is_a: GO:0031329 {is_inferred="true"} ! regulation of cellular catabolic process
 
 [Term]
 id: GO:0010507 ! negative regulation of autophagy
 is_a: GO:0010506 {is_inferred="true"} ! regulation of autophagy
-is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
+is_a: GO:0031330 {is_inferred="true"} ! negative regulation of cellular catabolic process
 
 [Term]
 id: GO:0010508 ! positive regulation of autophagy
 is_a: GO:0010506 {is_inferred="true"} ! regulation of autophagy
-is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
+is_a: GO:0031331 {is_inferred="true"} ! positive regulation of cellular catabolic process
 
 [Term]
 id: GO:0010509 ! polyamine homeostasis
@@ -28210,6 +28230,10 @@
 is_a: GO:1990234 {is_inferred="true"} ! transferase complex
 
 [Term]
+id: GO:0034727 ! piecemeal microautophagy of nucleus
+is_a: GO:0044804 {is_inferred="true"} ! nucleophagy
+
+[Term]
 id: GO:0034728 ! nucleosome organization
 is_a: GO:0071824 {is_inferred="true"} ! protein-DNA complex subunit organization
 
@@ -49115,6 +49139,10 @@
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 
 [Term]
+id: GO:0061684 ! chaperone-mediated autophagy
+is_a: GO:0030163 {is_inferred="true"} ! protein catabolic process
+
+[Term]
 id: GO:0061704 ! glycolytic process from sucrose
 is_a: GO:0005987 {is_inferred="true"} ! sucrose catabolic process
 
@@ -49129,6 +49157,10 @@
 is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 
 [Term]
+id: GO:0061709 ! reticulophagy
+is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
+
+[Term]
 id: GO:0061716 ! miRNA export from nucleus
 is_a: GO:1990428 {is_inferred="true"} ! miRNA transport
 
@@ -49163,6 +49195,10 @@
 is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
 
 [Term]
+id: GO:0061723 ! glycophagy
+is_a: GO:0005980 {is_inferred="true"} ! glycogen catabolic process
+
+[Term]
 id: GO:0061726 ! mitochondrion disassembly
 is_a: GO:0007005 {is_inferred="true"} ! mitochondrion organization
 
@@ -83065,13 +83101,11 @@
 [Term]
 id: GO:1904502 ! regulation of lipophagy
 is_a: GO:0016241 {is_inferred="true"} ! regulation of macroautophagy
-is_a: GO:0031329 {is_inferred="true"} ! regulation of cellular catabolic process
 is_a: GO:0050994 {is_inferred="true"} ! regulation of lipid catabolic process
 
 [Term]
 id: GO:1904503 ! negative regulation of lipophagy
 is_a: GO:0016242 {is_inferred="true"} ! negative regulation of macroautophagy
-is_a: GO:0031330 {is_inferred="true"} ! negative regulation of cellular catabolic process
 is_a: GO:0050995 {is_inferred="true"} ! negative regulation of lipid catabolic process
 is_a: GO:1904502 {is_inferred="true"} ! regulation of lipophagy
 
@@ -83078,7 +83112,6 @@
 [Term]
 id: GO:1904504 ! positive regulation of lipophagy
 is_a: GO:0016239 {is_inferred="true"} ! positive regulation of macroautophagy
-is_a: GO:0031331 {is_inferred="true"} ! positive regulation of cellular catabolic process
 is_a: GO:0050996 {is_inferred="true"} ! positive regulation of lipid catabolic process
 is_a: GO:1904502 {is_inferred="true"} ! regulation of lipophagy
 
@@ -84089,15 +84122,18 @@
 [Term]
 id: GO:1904714 ! regulation of chaperone-mediated autophagy
 is_a: GO:0010506 {is_inferred="true"} ! regulation of autophagy
+is_a: GO:0042176 {is_inferred="true"} ! regulation of protein catabolic process
 
 [Term]
 id: GO:1904715 ! negative regulation of chaperone-mediated autophagy
 is_a: GO:0010507 {is_inferred="true"} ! negative regulation of autophagy
+is_a: GO:0042177 {is_inferred="true"} ! negative regulation of protein catabolic process
 is_a: GO:1904714 {is_inferred="true"} ! regulation of chaperone-mediated autophagy
 
 [Term]
 id: GO:1904716 ! positive regulation of chaperone-mediated autophagy
 is_a: GO:0010508 {is_inferred="true"} ! positive regulation of autophagy
+is_a: GO:0045732 {is_inferred="true"} ! positive regulation of protein catabolic process
 is_a: GO:1904714 {is_inferred="true"} ! regulation of chaperone-mediated autophagy
 
 [Term]
------------------------------------------------------------------------
r38589 | davidos | 2017-02-05 14:06:32 -0800 (Sun, 05 Feb 2017) | 1 line

Added synapses as described in geneontology/synapse/issues/109.  Also fixed #11218.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38589)
+++ go_inferences.obo	(working copy)
@@ -3256,6 +3256,7 @@
 is_a: GO:0002831 {is_inferred="true"} ! regulation of response to biotic stimulus
 is_a: GO:0002920 {is_inferred="true"} ! regulation of humoral immune response
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
+is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 
 [Term]
 id: GO:0002760 ! positive regulation of antimicrobial humoral response
@@ -3263,6 +3264,7 @@
 is_a: GO:0002833 {is_inferred="true"} ! positive regulation of response to biotic stimulus
 is_a: GO:0002922 {is_inferred="true"} ! positive regulation of humoral immune response
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
+is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 
 [Term]
 id: GO:0002761 ! regulation of myeloid leukocyte differentiation
@@ -8601,6 +8603,7 @@
 is_a: GO:0002832 {is_inferred="true"} ! negative regulation of response to biotic stimulus
 is_a: GO:0002921 {is_inferred="true"} ! negative regulation of humoral immune response
 is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
+is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 
 [Term]
 id: GO:0008354 ! germ cell migration
@@ -10163,7 +10166,7 @@
 is_a: GO:0098543 {is_inferred="true"} ! detection of other organism
 
 [Term]
-id: GO:0009616 ! virus induced gene silencing
+id: GO:0009615 ! response to virus
 is_a: GO:0016032 {is_inferred="true"} ! viral process
 
 [Term]
@@ -11024,6 +11027,7 @@
 id: GO:0010112 ! regulation of systemic acquired resistance
 is_a: GO:0002831 {is_inferred="true"} ! regulation of response to biotic stimulus
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
+is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 is_a: GO:0045088 {is_inferred="true"} ! regulation of innate immune response
 
 [Term]
@@ -11031,6 +11035,7 @@
 is_a: GO:0002832 {is_inferred="true"} ! negative regulation of response to biotic stimulus
 is_a: GO:0010112 {is_inferred="true"} ! regulation of systemic acquired resistance
 is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
+is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:0045824 {is_inferred="true"} ! negative regulation of innate immune response
 
 [Term]
@@ -22338,6 +22343,7 @@
 is_a: GO:0002831 {is_inferred="true"} ! regulation of response to biotic stimulus
 is_a: GO:0009966 {is_inferred="true"} ! regulation of signal transduction
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
+is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 
 [Term]
 id: GO:0031665 ! negative regulation of lipopolysaccharide-mediated signaling pathway
@@ -22345,6 +22351,7 @@
 is_a: GO:0009968 {is_inferred="true"} ! negative regulation of signal transduction
 is_a: GO:0031664 {is_inferred="true"} ! regulation of lipopolysaccharide-mediated signaling pathway
 is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
+is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 
 [Term]
 id: GO:0031666 ! positive regulation of lipopolysaccharide-mediated signaling pathway
@@ -22352,6 +22359,7 @@
 is_a: GO:0009967 {is_inferred="true"} ! positive regulation of signal transduction
 is_a: GO:0031664 {is_inferred="true"} ! regulation of lipopolysaccharide-mediated signaling pathway
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
+is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 
 [Term]
 id: GO:0031670 ! cellular response to nutrient
@@ -29632,7 +29640,7 @@
 [Term]
 id: GO:0035947 ! regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter
 is_a: GO:0006111 {is_inferred="true"} ! regulation of gluconeogenesis
-is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
+is_a: GO:1900402 {is_inferred="true"} ! regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter
 
 [Term]
 id: GO:0035948 ! positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
@@ -29682,7 +29690,7 @@
 
 [Term]
 id: GO:0035956 ! regulation of starch catabolic process by regulation of transcription from RNA polymerase II promoter
-is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
+is_a: GO:0098679 {is_inferred="true"} ! regulation of carbohydrate catabolic process by regulation of transcription from RNA polymerase II promoter
 is_a: GO:2000881 {is_inferred="true"} ! regulation of starch catabolic process
 
 [Term]
@@ -29694,6 +29702,7 @@
 [Term]
 id: GO:0035958 ! regulation of glyoxylate cycle by regulation of transcription from RNA polymerase II promoter
 is_a: GO:0072364 {is_inferred="true"} ! regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter
+is_a: GO:1900402 {is_inferred="true"} ! regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter
 is_a: GO:2000874 {is_inferred="true"} ! regulation of glyoxylate cycle
 
 [Term]
@@ -42443,6 +42452,7 @@
 is_a: GO:0002832 {is_inferred="true"} ! negative regulation of response to biotic stimulus
 is_a: GO:0031348 {is_inferred="true"} ! negative regulation of defense response
 is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
+is_a: GO:0048525 {is_inferred="true"} ! negative regulation of viral process
 is_a: GO:0050688 {is_inferred="true"} ! regulation of defense response to virus
 
 [Term]
@@ -42451,6 +42461,7 @@
 is_a: GO:0002831 {is_inferred="true"} ! regulation of response to biotic stimulus
 is_a: GO:0031347 {is_inferred="true"} ! regulation of defense response
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
+is_a: GO:0050792 {is_inferred="true"} ! regulation of viral process
 
 [Term]
 id: GO:0050696 ! trichloroethylene catabolic process
@@ -54010,7 +54021,7 @@
 [Term]
 id: GO:0072361 ! regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter
 is_a: GO:0006110 {is_inferred="true"} ! regulation of glycolytic process
-is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
+is_a: GO:0098679 {is_inferred="true"} ! regulation of carbohydrate catabolic process by regulation of transcription from RNA polymerase II promoter
 
 [Term]
 id: GO:0072362 ! regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter
@@ -57367,6 +57378,11 @@
 is_a: GO:0098815 {is_inferred="true"} ! modulation of excitatory postsynaptic potential
 
 [Term]
+id: GO:0090401 ! viral-induced premature senescence
+is_a: GO:0044111 {is_inferred="true"} ! development involved in symbiotic interaction
+is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
+
+[Term]
 id: GO:0090407 ! organophosphate biosynthetic process
 is_a: GO:0019637 {is_inferred="true"} ! organophosphate metabolic process
 is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
@@ -58442,6 +58458,7 @@
 id: GO:0098522 ! neuromuscular junction of skeletal muscle fiber
 is_a: GO:0098520 {is_inferred="true"} ! excitatory neuromuscular junction
 is_a: GO:0098523 {is_inferred="true"} ! neuromuscular junction of myotube
+is_a: GO:0098981 {is_inferred="true"} ! cholinergic synapse
 
 [Term]
 id: GO:0098523 ! neuromuscular junction of myotube
@@ -58793,6 +58810,15 @@
 is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 
 [Term]
+id: GO:0098679 ! regulation of carbohydrate catabolic process by regulation of transcription from RNA polymerase II promoter
+is_a: GO:0043470 {is_inferred="true"} ! regulation of carbohydrate catabolic process
+is_a: GO:1900402 {is_inferred="true"} ! regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter
+
+[Term]
+id: GO:0098682 ! arciform density
+is_a: GO:0044456 {is_inferred="true"} ! synapse part
+
+[Term]
 id: GO:0098700 ! neurotransmitter loading into synaptic vesicle
 is_a: GO:0006836 {is_inferred="true"} ! neurotransmitter transport
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
@@ -61626,6 +61652,7 @@
 is_a: GO:0002831 {is_inferred="true"} ! regulation of response to biotic stimulus
 is_a: GO:0031347 {is_inferred="true"} ! regulation of defense response
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
+is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 
 [Term]
 id: GO:1900151 ! regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
@@ -62080,6 +62107,7 @@
 is_a: GO:0031349 {is_inferred="true"} ! positive regulation of defense response
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
 is_a: GO:0039533 {is_inferred="true"} ! regulation of MDA-5 signaling pathway
+is_a: GO:0048524 {is_inferred="true"} ! positive regulation of viral process
 is_a: GO:1902533 {is_inferred="true"} ! positive regulation of intracellular signal transduction
 
 [Term]
@@ -62089,6 +62117,7 @@
 is_a: GO:0031349 {is_inferred="true"} ! positive regulation of defense response
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
 is_a: GO:0039535 {is_inferred="true"} ! regulation of RIG-I signaling pathway
+is_a: GO:0048524 {is_inferred="true"} ! positive regulation of viral process
 is_a: GO:1902533 {is_inferred="true"} ! positive regulation of intracellular signal transduction
 
 [Term]
@@ -62693,6 +62722,7 @@
 is_a: GO:0002832 {is_inferred="true"} ! negative regulation of response to biotic stimulus
 is_a: GO:0031348 {is_inferred="true"} ! negative regulation of defense response
 is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
+is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:2000068 {is_inferred="true"} ! regulation of defense response to insect
 
 [Term]
@@ -62700,6 +62730,7 @@
 is_a: GO:0002833 {is_inferred="true"} ! positive regulation of response to biotic stimulus
 is_a: GO:0031349 {is_inferred="true"} ! positive regulation of defense response
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
+is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:2000068 {is_inferred="true"} ! regulation of defense response to insect
 
 [Term]
@@ -62744,6 +62775,7 @@
 id: GO:1900375 ! positive regulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter
 is_a: GO:0045944 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter
 is_a: GO:1900090 {is_inferred="true"} ! positive regulation of inositol biosynthetic process
+is_a: GO:1900402 {is_inferred="true"} ! regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter
 
 [Term]
 id: GO:1900376 ! regulation of secondary metabolite biosynthetic process
@@ -62969,6 +63001,7 @@
 is_a: GO:0002831 {is_inferred="true"} ! regulation of response to biotic stimulus
 is_a: GO:0031347 {is_inferred="true"} ! regulation of defense response
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
+is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 
 [Term]
 id: GO:1900425 ! negative regulation of defense response to bacterium
@@ -62975,6 +63008,7 @@
 is_a: GO:0002832 {is_inferred="true"} ! negative regulation of response to biotic stimulus
 is_a: GO:0031348 {is_inferred="true"} ! negative regulation of defense response
 is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
+is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:1900424 {is_inferred="true"} ! regulation of defense response to bacterium
 
 [Term]
@@ -62982,6 +63016,7 @@
 is_a: GO:0002833 {is_inferred="true"} ! positive regulation of response to biotic stimulus
 is_a: GO:0031349 {is_inferred="true"} ! positive regulation of defense response
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
+is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:1900424 {is_inferred="true"} ! regulation of defense response to bacterium
 
 [Term]
@@ -63206,6 +63241,7 @@
 is_a: GO:0000122 {is_inferred="true"} ! negative regulation of transcription from RNA polymerase II promoter
 is_a: GO:0010678 {is_inferred="true"} ! negative regulation of cellular carbohydrate metabolic process by negative regulation of transcription, DNA-templated
 is_a: GO:1900089 {is_inferred="true"} ! negative regulation of inositol biosynthetic process
+is_a: GO:1900402 {is_inferred="true"} ! regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter
 
 [Term]
 id: GO:1900472 ! positive regulation of phosphatidylcholine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter
@@ -69455,6 +69491,7 @@
 is_a: GO:0002833 {is_inferred="true"} ! positive regulation of response to biotic stimulus
 is_a: GO:0010112 {is_inferred="true"} ! regulation of systemic acquired resistance
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
+is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:0045089 {is_inferred="true"} ! positive regulation of innate immune response
 
 [Term]
@@ -72612,6 +72649,7 @@
 is_a: GO:0002831 {is_inferred="true"} ! regulation of response to biotic stimulus
 is_a: GO:0031347 {is_inferred="true"} ! regulation of defense response
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
+is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 
 [Term]
 id: GO:1902289 ! negative regulation of defense response to oomycetes
@@ -72618,6 +72656,7 @@
 is_a: GO:0002832 {is_inferred="true"} ! negative regulation of response to biotic stimulus
 is_a: GO:0031348 {is_inferred="true"} ! negative regulation of defense response
 is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
+is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:1902288 {is_inferred="true"} ! regulation of defense response to oomycetes
 
 [Term]
@@ -72625,6 +72664,7 @@
 is_a: GO:0002833 {is_inferred="true"} ! positive regulation of response to biotic stimulus
 is_a: GO:0031349 {is_inferred="true"} ! positive regulation of defense response
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
+is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:1902288 {is_inferred="true"} ! regulation of defense response to oomycetes
 
 [Term]
@@ -82574,6 +82614,7 @@
 is_a: GO:0016241 {is_inferred="true"} ! regulation of macroautophagy
 is_a: GO:0031347 {is_inferred="true"} ! regulation of defense response
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
+is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 
 [Term]
 id: GO:1904416 ! negative regulation of xenophagy
@@ -82581,6 +82622,7 @@
 is_a: GO:0016242 {is_inferred="true"} ! negative regulation of macroautophagy
 is_a: GO:0031348 {is_inferred="true"} ! negative regulation of defense response
 is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
+is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:1904415 {is_inferred="true"} ! regulation of xenophagy
 
 [Term]
@@ -82589,6 +82631,7 @@
 is_a: GO:0016239 {is_inferred="true"} ! positive regulation of macroautophagy
 is_a: GO:0031349 {is_inferred="true"} ! positive regulation of defense response
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
+is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:1904415 {is_inferred="true"} ! regulation of xenophagy
 
 [Term]
@@ -85615,6 +85658,7 @@
 id: GO:1905035 ! negative regulation of antifungal innate immune response
 is_a: GO:0002832 {is_inferred="true"} ! negative regulation of response to biotic stimulus
 is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
+is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:0045824 {is_inferred="true"} ! negative regulation of innate immune response
 is_a: GO:1905034 {is_inferred="true"} ! regulation of antifungal innate immune response
 
@@ -85622,6 +85666,7 @@
 id: GO:1905036 ! positive regulation of antifungal innate immune response
 is_a: GO:0002833 {is_inferred="true"} ! positive regulation of response to biotic stimulus
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
+is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:0045089 {is_inferred="true"} ! positive regulation of innate immune response
 is_a: GO:1905034 {is_inferred="true"} ! regulation of antifungal innate immune response
 
@@ -91182,6 +91227,7 @@
 is_a: GO:0002831 {is_inferred="true"} ! regulation of response to biotic stimulus
 is_a: GO:0031347 {is_inferred="true"} ! regulation of defense response
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
+is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 
 [Term]
 id: GO:2000069 ! regulation of post-embryonic root development
------------------------------------------------------------------------
r38574 | tberardi | 2017-02-03 17:42:01 -0800 (Fri, 03 Feb 2017) | 1 line

GH12986 NTR site of DNA damage - closed

changes in entailments

------------------------------------------------------------------------
r38572 | tberardi | 2017-02-03 17:20:51 -0800 (Fri, 03 Feb 2017) | 1 line

GH12994 add F-P link for molecular function regulator - closed

changes in entailments

------------------------------------------------------------------------
r38570 | hjd | 2017-02-03 13:01:10 -0800 (Fri, 03 Feb 2017) | 2 lines

removed term with duplicate name

changes in entailments

------------------------------------------------------------------------
r38567 | termgenie | 2017-02-03 09:24:17 -0800 (Fri, 03 Feb 2017) | 4 lines

TermGenie commit for user: BarbaraCzub reviewed by tberardini

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38567)
+++ go_inferences.obo	(working copy)
@@ -89091,23 +89091,20 @@
 
 [Term]
 id: GO:1905770 ! regulation of mesodermal cell differentiation
-is_a: GO:0010470 {is_inferred="true"} ! regulation of gastrulation
 is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
-is_a: GO:2000380 {is_inferred="true"} ! regulation of mesoderm development
+is_a: GO:1905902 {is_inferred="true"} ! regulation of mesoderm formation
 
 [Term]
 id: GO:1905771 ! negative regulation of mesodermal cell differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
 is_a: GO:1905770 {is_inferred="true"} ! regulation of mesodermal cell differentiation
-is_a: GO:2000381 {is_inferred="true"} ! negative regulation of mesoderm development
-is_a: GO:2000542 {is_inferred="true"} ! negative regulation of gastrulation
+is_a: GO:1905903 {is_inferred="true"} ! negative regulation of mesoderm formation
 
 [Term]
 id: GO:1905772 ! positive regulation of mesodermal cell differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
 is_a: GO:1905770 {is_inferred="true"} ! regulation of mesodermal cell differentiation
-is_a: GO:2000382 {is_inferred="true"} ! positive regulation of mesoderm development
-is_a: GO:2000543 {is_inferred="true"} ! positive regulation of gastrulation
+is_a: GO:1905904 {is_inferred="true"} ! positive regulation of mesoderm formation
 
 [Term]
 id: GO:1905774 ! regulation of DNA helicase activity
@@ -89787,6 +89784,44 @@
 is_a: GO:1905899 {is_inferred="true"} ! regulation of smooth muscle tissue development
 
 [Term]
+id: GO:1905902 ! regulation of mesoderm formation
+is_a: GO:0010470 {is_inferred="true"} ! regulation of gastrulation
+is_a: GO:2000380 {is_inferred="true"} ! regulation of mesoderm development
+
+[Term]
+id: GO:1905903 ! negative regulation of mesoderm formation
+is_a: GO:1905902 {is_inferred="true"} ! regulation of mesoderm formation
+is_a: GO:2000381 {is_inferred="true"} ! negative regulation of mesoderm development
+is_a: GO:2000542 {is_inferred="true"} ! negative regulation of gastrulation
+
+[Term]
+id: GO:1905904 ! positive regulation of mesoderm formation
+is_a: GO:1905902 {is_inferred="true"} ! regulation of mesoderm formation
+is_a: GO:2000382 {is_inferred="true"} ! positive regulation of mesoderm development
+is_a: GO:2000543 {is_inferred="true"} ! positive regulation of gastrulation
+
+[Term]
+id: GO:1905905 ! pharyngeal gland morphogenesis
+is_a: GO:0022612 {is_inferred="true"} ! gland morphogenesis
+
+[Term]
+id: GO:1905906 ! regulation of amyloid fibril formation
+is_a: GO:0051246 {is_inferred="true"} ! regulation of protein metabolic process
+is_a: GO:1902903 {is_inferred="true"} ! regulation of supramolecular fiber organization
+
+[Term]
+id: GO:1905907 ! negative regulation of amyloid fibril formation
+is_a: GO:0051248 {is_inferred="true"} ! negative regulation of protein metabolic process
+is_a: GO:1902904 {is_inferred="true"} ! negative regulation of supramolecular fiber organization
+is_a: GO:1905906 {is_inferred="true"} ! regulation of amyloid fibril formation
+
+[Term]
+id: GO:1905908 ! positive regulation of amyloid fibril formation
+is_a: GO:0051247 {is_inferred="true"} ! positive regulation of protein metabolic process
+is_a: GO:1902905 {is_inferred="true"} ! positive regulation of supramolecular fiber organization
+is_a: GO:1905906 {is_inferred="true"} ! regulation of amyloid fibril formation
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r38557 | termgenie | 2017-02-02 12:28:56 -0800 (Thu, 02 Feb 2017) | 2 lines

TermGenie commit for user: pgarmiri reviewed by tberardini

changes in entailments

------------------------------------------------------------------------
r38555 | cjm | 2017-02-02 11:43:32 -0800 (Thu, 02 Feb 2017) | 1 line

killing EC dashes forever, https://github.com/geneontology/go-ontology/issues/12988

changes in entailments

------------------------------------------------------------------------
r38542 | tberardi | 2017-02-01 17:29:17 -0800 (Wed, 01 Feb 2017) | 1 line

GH12892  Transcription occurs_in nuclear chromatin - closed again

changes in entailments

------------------------------------------------------------------------
r38540 | tberardi | 2017-02-01 16:49:24 -0800 (Wed, 01 Feb 2017) | 1 line

GH12983 NTR: Tenascin complex - closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38540)
+++ go_inferences.obo	(working copy)
@@ -57685,6 +57685,10 @@
 is_a: GO:0044445 {is_inferred="true"} ! cytosolic part
 
 [Term]
+id: GO:0090733 ! tenascin complex
+is_a: GO:0044420 {is_inferred="true"} ! extracellular matrix component
+
+[Term]
 id: GO:0093001 ! glycolysis from storage polysaccharide through glucose-1-phosphate
 is_a: GO:0000272 {is_inferred="true"} ! polysaccharide catabolic process
 is_a: GO:0061622 {is_inferred="true"} ! glycolytic process through glucose-1-phosphate
------------------------------------------------------------------------
r38538 | termgenie | 2017-02-01 16:21:25 -0800 (Wed, 01 Feb 2017) | 3 lines

TermGenie commit for user: BarbaraCzub reviewed by tberardini

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38538)
+++ go_inferences.obo	(working copy)
@@ -47504,6 +47504,7 @@
 [Term]
 id: GO:0060734 ! regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
 is_a: GO:0006446 {is_inferred="true"} ! regulation of translational initiation
+is_a: GO:1905897 {is_inferred="true"} ! regulation of response to endoplasmic reticulum stress
 
 [Term]
 id: GO:0060735 ! regulation of eIF2 alpha phosphorylation by dsRNA
@@ -61367,7 +61368,7 @@
 [Term]
 id: GO:1900101 ! regulation of endoplasmic reticulum unfolded protein response
 is_a: GO:0009966 {is_inferred="true"} ! regulation of signal transduction
-is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
+is_a: GO:1905897 {is_inferred="true"} ! regulation of response to endoplasmic reticulum stress
 
 [Term]
 id: GO:1900102 ! negative regulation of endoplasmic reticulum unfolded protein response
@@ -61379,6 +61380,7 @@
 id: GO:1900103 ! positive regulation of endoplasmic reticulum unfolded protein response
 is_a: GO:0009967 {is_inferred="true"} ! positive regulation of signal transduction
 is_a: GO:1900101 {is_inferred="true"} ! regulation of endoplasmic reticulum unfolded protein response
+is_a: GO:1905898 {is_inferred="true"} ! positive regulation of response to endoplasmic reticulum stress
 
 [Term]
 id: GO:1900104 ! regulation of hyaluranon cable assembly
@@ -72340,7 +72342,7 @@
 
 [Term]
 id: GO:1902235 ! regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
-is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
+is_a: GO:1905897 {is_inferred="true"} ! regulation of response to endoplasmic reticulum stress
 is_a: GO:2001242 {is_inferred="true"} ! regulation of intrinsic apoptotic signaling pathway
 
 [Term]
@@ -72352,6 +72354,7 @@
 [Term]
 id: GO:1902237 ! positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
 is_a: GO:1902235 {is_inferred="true"} ! regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
+is_a: GO:1905898 {is_inferred="true"} ! positive regulation of response to endoplasmic reticulum stress
 is_a: GO:2001244 {is_inferred="true"} ! positive regulation of intrinsic apoptotic signaling pathway
 
 [Term]
@@ -78529,7 +78532,7 @@
 id: GO:1903573 ! negative regulation of response to endoplasmic reticulum stress
 is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
 is_a: GO:0048585 {is_inferred="true"} ! negative regulation of response to stimulus
-is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
+is_a: GO:1905897 {is_inferred="true"} ! regulation of response to endoplasmic reticulum stress
 
 [Term]
 id: GO:1903574 ! negative regulation of cellular response to amino acid starvation
@@ -80172,14 +80175,14 @@
 is_a: GO:0032535 {is_inferred="true"} ! regulation of cellular component size
 is_a: GO:0035304 {is_inferred="true"} ! regulation of protein dephosphorylation
 is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
-is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
+is_a: GO:1905897 {is_inferred="true"} ! regulation of response to endoplasmic reticulum stress
 
 [Term]
 id: GO:1903917 ! positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation
 is_a: GO:0035307 {is_inferred="true"} ! positive regulation of protein dephosphorylation
-is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
 is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 is_a: GO:1903916 {is_inferred="true"} ! regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation
+is_a: GO:1905898 {is_inferred="true"} ! positive regulation of response to endoplasmic reticulum stress
 
 [Term]
 id: GO:1903918 ! regulation of actin filament severing
@@ -81971,7 +81974,7 @@
 [Term]
 id: GO:1904292 ! regulation of ERAD pathway
 is_a: GO:0042176 {is_inferred="true"} ! regulation of protein catabolic process
-is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
+is_a: GO:1905897 {is_inferred="true"} ! regulation of response to endoplasmic reticulum stress
 
 [Term]
 id: GO:1904293 ! negative regulation of ERAD pathway
@@ -81982,9 +81985,8 @@
 [Term]
 id: GO:1904294 ! positive regulation of ERAD pathway
 is_a: GO:0045732 {is_inferred="true"} ! positive regulation of protein catabolic process
-is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
-is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
 is_a: GO:1904292 {is_inferred="true"} ! regulation of ERAD pathway
+is_a: GO:1905898 {is_inferred="true"} ! positive regulation of response to endoplasmic reticulum stress
 
 [Term]
 id: GO:1904295 ! regulation of osmolarity-sensing cation channel activity
@@ -89757,6 +89759,16 @@
 is_a: GO:1905894 {is_inferred="true"} ! regulation of cellular response to tunicamycin
 
 [Term]
+id: GO:1905897 ! regulation of response to endoplasmic reticulum stress
+is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
+
+[Term]
+id: GO:1905898 ! positive regulation of response to endoplasmic reticulum stress
+is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
+is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
+is_a: GO:1905897 {is_inferred="true"} ! regulation of response to endoplasmic reticulum stress
+
+[Term]
 id: GO:1905899 ! regulation of smooth muscle tissue development
 is_a: GO:1901861 {is_inferred="true"} ! regulation of muscle tissue development
 
------------------------------------------------------------------------
r38536 | tberardi | 2017-02-01 15:45:53 -0800 (Wed, 01 Feb 2017) | 1 line

GH12977 cellular response to very-low-density lipoprotein particle stimulus - closed again

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38536)
+++ go_inferences.obo	(working copy)
@@ -89702,9 +89702,75 @@
 
 [Term]
 id: GO:1905887 ! autoinducer AI-2 transmembrane transport
+is_a: GO:0015791 {is_inferred="true"} ! polyol transport
 is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
 
 [Term]
+id: GO:1905888 ! negative regulation of cellular response to very-low-density lipoprotein particle stimulus
+is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
+is_a: GO:0048585 {is_inferred="true"} ! negative regulation of response to stimulus
+is_a: GO:1905890 {is_inferred="true"} ! regulation of cellular response to very-low-density lipoprotein particle stimulus
+
+[Term]
+id: GO:1905889 ! positive regulation of cellular response to very-low-density lipoprotein particle stimulus
+is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
+is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
+is_a: GO:1905890 {is_inferred="true"} ! regulation of cellular response to very-low-density lipoprotein particle stimulus
+
+[Term]
+id: GO:1905890 ! regulation of cellular response to very-low-density lipoprotein particle stimulus
+is_a: GO:0048583 {is_inferred="true"} ! regulation of response to stimulus
+is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
+
+[Term]
+id: GO:1905891 ! regulation of cellular response to thapsigargin
+is_a: GO:0048583 {is_inferred="true"} ! regulation of response to stimulus
+is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
+
+[Term]
+id: GO:1905892 ! negative regulation of cellular response to thapsigargin
+is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
+is_a: GO:0048585 {is_inferred="true"} ! negative regulation of response to stimulus
+is_a: GO:1905891 {is_inferred="true"} ! regulation of cellular response to thapsigargin
+
+[Term]
+id: GO:1905893 ! positive regulation of cellular response to thapsigargin
+is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
+is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
+is_a: GO:1905891 {is_inferred="true"} ! regulation of cellular response to thapsigargin
+
+[Term]
+id: GO:1905894 ! regulation of cellular response to tunicamycin
+is_a: GO:0048583 {is_inferred="true"} ! regulation of response to stimulus
+is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
+
+[Term]
+id: GO:1905895 ! negative regulation of cellular response to tunicamycin
+is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
+is_a: GO:0048585 {is_inferred="true"} ! negative regulation of response to stimulus
+is_a: GO:1905894 {is_inferred="true"} ! regulation of cellular response to tunicamycin
+
+[Term]
+id: GO:1905896 ! positive regulation of cellular response to tunicamycin
+is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
+is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
+is_a: GO:1905894 {is_inferred="true"} ! regulation of cellular response to tunicamycin
+
+[Term]
+id: GO:1905899 ! regulation of smooth muscle tissue development
+is_a: GO:1901861 {is_inferred="true"} ! regulation of muscle tissue development
+
+[Term]
+id: GO:1905900 ! negative regulation of smooth muscle tissue development
+is_a: GO:1901862 {is_inferred="true"} ! negative regulation of muscle tissue development
+is_a: GO:1905899 {is_inferred="true"} ! regulation of smooth muscle tissue development
+
+[Term]
+id: GO:1905901 ! positive regulation of smooth muscle tissue development
+is_a: GO:1901863 {is_inferred="true"} ! positive regulation of muscle tissue development
+is_a: GO:1905899 {is_inferred="true"} ! regulation of smooth muscle tissue development
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
@@ -91024,13 +91090,13 @@
 [Term]
 id: GO:2000061 ! regulation of ureter smooth muscle cell differentiation
 is_a: GO:0051150 {is_inferred="true"} ! regulation of smooth muscle cell differentiation
-is_a: GO:1901861 {is_inferred="true"} ! regulation of muscle tissue development
+is_a: GO:1905899 {is_inferred="true"} ! regulation of smooth muscle tissue development
 
 [Term]
 id: GO:2000062 ! negative regulation of ureter smooth muscle cell differentiation
 is_a: GO:0051151 {is_inferred="true"} ! negative regulation of smooth muscle cell differentiation
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-is_a: GO:1901862 {is_inferred="true"} ! negative regulation of muscle tissue development
+is_a: GO:1905900 {is_inferred="true"} ! negative regulation of smooth muscle tissue development
 is_a: GO:2000061 {is_inferred="true"} ! regulation of ureter smooth muscle cell differentiation
 
 [Term]
@@ -91037,7 +91103,7 @@
 id: GO:2000063 ! positive regulation of ureter smooth muscle cell differentiation
 is_a: GO:0051152 {is_inferred="true"} ! positive regulation of smooth muscle cell differentiation
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-is_a: GO:1901863 {is_inferred="true"} ! positive regulation of muscle tissue development
+is_a: GO:1905901 {is_inferred="true"} ! positive regulation of smooth muscle tissue development
 is_a: GO:2000061 {is_inferred="true"} ! regulation of ureter smooth muscle cell differentiation
 
 [Term]
@@ -92454,13 +92520,13 @@
 id: GO:2000356 ! regulation of kidney smooth muscle cell differentiation
 is_a: GO:0051150 {is_inferred="true"} ! regulation of smooth muscle cell differentiation
 is_a: GO:0090183 {is_inferred="true"} ! regulation of kidney development
-is_a: GO:1901861 {is_inferred="true"} ! regulation of muscle tissue development
+is_a: GO:1905899 {is_inferred="true"} ! regulation of smooth muscle tissue development
 
 [Term]
 id: GO:2000357 ! negative regulation of kidney smooth muscle cell differentiation
 is_a: GO:0051151 {is_inferred="true"} ! negative regulation of smooth muscle cell differentiation
 is_a: GO:0090185 {is_inferred="true"} ! negative regulation of kidney development
-is_a: GO:1901862 {is_inferred="true"} ! negative regulation of muscle tissue development
+is_a: GO:1905900 {is_inferred="true"} ! negative regulation of smooth muscle tissue development
 is_a: GO:2000356 {is_inferred="true"} ! regulation of kidney smooth muscle cell differentiation
 
 [Term]
@@ -92467,7 +92533,7 @@
 id: GO:2000358 ! positive regulation of kidney smooth muscle cell differentiation
 is_a: GO:0051152 {is_inferred="true"} ! positive regulation of smooth muscle cell differentiation
 is_a: GO:0090184 {is_inferred="true"} ! positive regulation of kidney development
-is_a: GO:1901863 {is_inferred="true"} ! positive regulation of muscle tissue development
+is_a: GO:1905901 {is_inferred="true"} ! positive regulation of smooth muscle tissue development
 is_a: GO:2000356 {is_inferred="true"} ! regulation of kidney smooth muscle cell differentiation
 
 [Term]
------------------------------------------------------------------------
r38522 | tberardi | 2017-01-31 18:20:12 -0800 (Tue, 31 Jan 2017) | 1 line

GH12981 xref to EC for ... - xrefs fixed

changes in entailments

------------------------------------------------------------------------
r38518 | tberardi | 2017-01-31 17:51:47 -0800 (Tue, 31 Jan 2017) | 1 line

GH12543 NTR: maintenance of differentiated cell state - almost closed

changes in entailments

------------------------------------------------------------------------
r38516 | tberardi | 2017-01-31 17:46:18 -0800 (Tue, 31 Jan 2017) | 1 line

GH12979 cofilin-actin rod - closed

changes in entailments

------------------------------------------------------------------------
r38515 | tberardi | 2017-01-31 17:40:54 -0800 (Tue, 31 Jan 2017) | 1 line

GH12972 Add taxon restriction for carotenoid/ pombe and S. cerevisae - closed

changes in entailments

------------------------------------------------------------------------
r38513 | tberardi | 2017-01-31 17:20:55 -0800 (Tue, 31 Jan 2017) | 1 line

GH12978 cell elongation - closed

changes in entailments

------------------------------------------------------------------------
r38510 | tberardi | 2017-01-31 17:06:20 -0800 (Tue, 31 Jan 2017) | 1 line

GH12971 Two contradictory meanings for lipoprotein in GO - closed

changes in entailments

------------------------------------------------------------------------
r38508 | termgenie | 2017-01-31 16:40:09 -0800 (Tue, 31 Jan 2017) | 2 lines

TermGenie commit for user: mah11 reviewed by tberardini

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38508)
+++ go_inferences.obo	(working copy)
@@ -20561,29 +20561,21 @@
 id: GO:0030710 ! regulation of border follicle cell delamination
 is_a: GO:0022407 {is_inferred="true"} ! regulation of cell-cell adhesion
 is_a: GO:0030856 {is_inferred="true"} ! regulation of epithelial cell differentiation
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
-is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
-is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
+is_a: GO:1905879 {is_inferred="true"} ! regulation of oogenesis
 
 [Term]
 id: GO:0030711 ! positive regulation of border follicle cell delamination
-is_a: GO:0010720 {is_inferred="true"} ! positive regulation of cell development
 is_a: GO:0030710 {is_inferred="true"} ! regulation of border follicle cell delamination
 is_a: GO:0030858 {is_inferred="true"} ! positive regulation of epithelial cell differentiation
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
+is_a: GO:1905881 {is_inferred="true"} ! positive regulation of oogenesis
 
 [Term]
 id: GO:0030712 ! negative regulation of border follicle cell delamination
-is_a: GO:0010721 {is_inferred="true"} ! negative regulation of cell development
 is_a: GO:0022409 {is_inferred="true"} ! positive regulation of cell-cell adhesion
 is_a: GO:0030710 {is_inferred="true"} ! regulation of border follicle cell delamination
 is_a: GO:0030857 {is_inferred="true"} ! negative regulation of epithelial cell differentiation
-is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
+is_a: GO:1905880 {is_inferred="true"} ! negative regulation of oogenesis
 
 [Term]
 id: GO:0030713 ! ovarian follicle cell stalk formation
@@ -36162,11 +36154,8 @@
 
 [Term]
 id: GO:0045477 ! regulation of nurse cell apoptotic process
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
-is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
-is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
 is_a: GO:1904748 {is_inferred="true"} ! regulation of apoptotic process involved in development
-is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
+is_a: GO:1905879 {is_inferred="true"} ! regulation of oogenesis
 
 [Term]
 id: GO:0045478 ! fusome organization
@@ -36474,25 +36463,22 @@
 [Term]
 id: GO:0045592 ! regulation of cumulus cell differentiation
 is_a: GO:0030856 {is_inferred="true"} ! regulation of epithelial cell differentiation
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
-is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
+is_a: GO:1905879 {is_inferred="true"} ! regulation of oogenesis
 is_a: GO:2000387 {is_inferred="true"} ! regulation of antral ovarian follicle growth
 
 [Term]
 id: GO:0045593 ! negative regulation of cumulus cell differentiation
-is_a: GO:0010721 {is_inferred="true"} ! negative regulation of cell development
 is_a: GO:0030857 {is_inferred="true"} ! negative regulation of epithelial cell differentiation
-is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:0045592 {is_inferred="true"} ! regulation of cumulus cell differentiation
 is_a: GO:0048640 {is_inferred="true"} ! negative regulation of developmental growth
+is_a: GO:1905880 {is_inferred="true"} ! negative regulation of oogenesis
 is_a: GO:2000355 {is_inferred="true"} ! negative regulation of ovarian follicle development
 
 [Term]
 id: GO:0045594 ! positive regulation of cumulus cell differentiation
-is_a: GO:0010720 {is_inferred="true"} ! positive regulation of cell development
 is_a: GO:0030858 {is_inferred="true"} ! positive regulation of epithelial cell differentiation
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:0045592 {is_inferred="true"} ! regulation of cumulus cell differentiation
+is_a: GO:1905881 {is_inferred="true"} ! positive regulation of oogenesis
 is_a: GO:2000388 {is_inferred="true"} ! positive regulation of antral ovarian follicle growth
 
 [Term]
@@ -37474,19 +37460,15 @@
 
 [Term]
 id: GO:0045849 ! negative regulation of nurse cell apoptotic process
-is_a: GO:0010721 {is_inferred="true"} ! negative regulation of cell development
-is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:0045477 {is_inferred="true"} ! regulation of nurse cell apoptotic process
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1904746 {is_inferred="true"} ! negative regulation of apoptotic process involved in development
+is_a: GO:1905880 {is_inferred="true"} ! negative regulation of oogenesis
 
 [Term]
 id: GO:0045850 ! positive regulation of nurse cell apoptotic process
-is_a: GO:0010720 {is_inferred="true"} ! positive regulation of cell development
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:0045477 {is_inferred="true"} ! regulation of nurse cell apoptotic process
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1904747 {is_inferred="true"} ! positive regulation of apoptotic process involved in development
+is_a: GO:1905881 {is_inferred="true"} ! positive regulation of oogenesis
 
 [Term]
 id: GO:0045853 ! negative regulation of bicoid mRNA localization
@@ -46359,26 +46341,17 @@
 
 [Term]
 id: GO:0060281 ! regulation of oocyte development
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
-is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
-is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
-is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
+is_a: GO:1905879 {is_inferred="true"} ! regulation of oogenesis
 
 [Term]
 id: GO:0060282 ! positive regulation of oocyte development
-is_a: GO:0010720 {is_inferred="true"} ! positive regulation of cell development
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:0060281 {is_inferred="true"} ! regulation of oocyte development
-is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
+is_a: GO:1905881 {is_inferred="true"} ! positive regulation of oogenesis
 
 [Term]
 id: GO:0060283 ! negative regulation of oocyte development
-is_a: GO:0010721 {is_inferred="true"} ! negative regulation of cell development
-is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:0060281 {is_inferred="true"} ! regulation of oocyte development
-is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
+is_a: GO:1905880 {is_inferred="true"} ! negative regulation of oogenesis
 
 [Term]
 id: GO:0060287 ! epithelial cilium movement involved in determination of left/right asymmetry
@@ -79132,27 +79105,21 @@
 id: GO:1903684 ! regulation of border follicle cell migration
 is_a: GO:0010632 {is_inferred="true"} ! regulation of epithelial cell migration
 is_a: GO:0030856 {is_inferred="true"} ! regulation of epithelial cell differentiation
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
-is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
-is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
+is_a: GO:1905879 {is_inferred="true"} ! regulation of oogenesis
 
 [Term]
 id: GO:1903687 ! negative regulation of border follicle cell migration
 is_a: GO:0010633 {is_inferred="true"} ! negative regulation of epithelial cell migration
-is_a: GO:0010721 {is_inferred="true"} ! negative regulation of cell development
 is_a: GO:0030857 {is_inferred="true"} ! negative regulation of epithelial cell differentiation
-is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:1903684 {is_inferred="true"} ! regulation of border follicle cell migration
-is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
+is_a: GO:1905880 {is_inferred="true"} ! negative regulation of oogenesis
 
 [Term]
 id: GO:1903688 ! positive regulation of border follicle cell migration
 is_a: GO:0010634 {is_inferred="true"} ! positive regulation of epithelial cell migration
-is_a: GO:0010720 {is_inferred="true"} ! positive regulation of cell development
 is_a: GO:0030858 {is_inferred="true"} ! positive regulation of epithelial cell differentiation
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:1903684 {is_inferred="true"} ! regulation of border follicle cell migration
-is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
+is_a: GO:1905881 {is_inferred="true"} ! positive regulation of oogenesis
 
 [Term]
 id: GO:1903689 ! regulation of wound healing, spreading of epidermal cells
@@ -89692,6 +89659,48 @@
 is_a: GO:1905863 {is_inferred="true"} ! invadopodium organization
 
 [Term]
+id: GO:1905879 ! regulation of oogenesis
+is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
+is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
+is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
+is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
+
+[Term]
+id: GO:1905880 ! negative regulation of oogenesis
+is_a: GO:0010721 {is_inferred="true"} ! negative regulation of cell development
+is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
+is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
+is_a: GO:1905879 {is_inferred="true"} ! regulation of oogenesis
+is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
+
+[Term]
+id: GO:1905881 ! positive regulation of oogenesis
+is_a: GO:0010720 {is_inferred="true"} ! positive regulation of cell development
+is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
+is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
+is_a: GO:1905879 {is_inferred="true"} ! regulation of oogenesis
+is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
+
+[Term]
+id: GO:1905883 ! regulation of triglyceride transport
+is_a: GO:1901506 {is_inferred="true"} ! regulation of acylglycerol transport
+
+[Term]
+id: GO:1905884 ! negative regulation of triglyceride transport
+is_a: GO:1901507 {is_inferred="true"} ! negative regulation of acylglycerol transport
+is_a: GO:1905883 {is_inferred="true"} ! regulation of triglyceride transport
+
+[Term]
+id: GO:1905885 ! positive regulation of triglyceride transport
+is_a: GO:1901508 {is_inferred="true"} ! positive regulation of acylglycerol transport
+is_a: GO:1905883 {is_inferred="true"} ! regulation of triglyceride transport
+
+[Term]
+id: GO:1905886 ! chromatin remodeling involved in meiosis I
+is_a: GO:0006338 {is_inferred="true"} ! chromatin remodeling
+is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
+
+[Term]
 id: GO:1905887 ! autoinducer AI-2 transmembrane transport
 is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
 
------------------------------------------------------------------------
r38504 | termgenie | 2017-01-31 06:41:54 -0800 (Tue, 31 Jan 2017) | 2 lines

TermGenie commit for user: dosumis reviewed by dosumis

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38504)
+++ go_inferences.obo	(working copy)
@@ -89692,6 +89692,10 @@
 is_a: GO:1905863 {is_inferred="true"} ! invadopodium organization
 
 [Term]
+id: GO:1905887 ! autoinducer AI-2 transmembrane transport
+is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r38498 | dph | 2017-01-31 05:55:35 -0800 (Tue, 31 Jan 2017) | 2 lines

GH12966-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38498)
+++ go_inferences.obo	(working copy)
@@ -27988,6 +27988,10 @@
 is_a: GO:0033365 {is_inferred="true"} ! protein localization to organelle
 
 [Term]
+id: GO:0034506 ! chromosome, centromeric core domain
+is_a: GO:0098687 {is_inferred="true"} ! chromosomal region
+
+[Term]
 id: GO:0034507 ! chromosome, centromeric outer repeat region
 is_a: GO:0098687 {is_inferred="true"} ! chromosomal region
 
------------------------------------------------------------------------
r38486 | termgenie | 2017-01-30 16:37:12 -0800 (Mon, 30 Jan 2017) | 3 lines

TermGenie commit for user: slaulederkind reviewed by tberardini

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38486)
+++ go_inferences.obo	(working copy)
@@ -75453,9 +75453,9 @@
 
 [Term]
 id: GO:1902897 ! regulation of postsynaptic density protein 95 clustering
-is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
 is_a: GO:1901626 {is_inferred="true"} ! regulation of postsynaptic membrane organization
 is_a: GO:1905475 {is_inferred="true"} ! regulation of protein localization to membrane
+is_a: GO:1905874 {is_inferred="true"} ! regulation of postsynaptic density organization
 
 [Term]
 id: GO:1902898 ! fatty acid methyl ester metabolic process
@@ -89662,6 +89662,32 @@
 is_a: GO:1905871 {is_inferred="true"} ! regulation of protein localization to cell leading edge
 
 [Term]
+id: GO:1905874 ! regulation of postsynaptic density organization
+is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
+is_a: GO:0050807 {is_inferred="true"} ! regulation of synapse organization
+
+[Term]
+id: GO:1905875 ! negative regulation of postsynaptic density organization
+is_a: GO:0010639 {is_inferred="true"} ! negative regulation of organelle organization
+is_a: GO:1905809 {is_inferred="true"} ! negative regulation of synapse organization
+is_a: GO:1905874 {is_inferred="true"} ! regulation of postsynaptic density organization
+
+[Term]
+id: GO:1905876 ! positive regulation of postsynaptic density organization
+is_a: GO:0010638 {is_inferred="true"} ! positive regulation of organelle organization
+is_a: GO:1905874 {is_inferred="true"} ! regulation of postsynaptic density organization
+
+[Term]
+id: GO:1905877 ! invadopodium assembly
+is_a: GO:0030031 {is_inferred="true"} ! cell projection assembly
+is_a: GO:1905863 {is_inferred="true"} ! invadopodium organization
+
+[Term]
+id: GO:1905878 ! invadopodium disassembly
+is_a: GO:0022411 {is_inferred="true"} ! cellular component disassembly
+is_a: GO:1905863 {is_inferred="true"} ! invadopodium organization
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r38477 | dph | 2017-01-30 06:22:44 -0800 (Mon, 30 Jan 2017) | 2 lines

GH12965-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38477)
+++ go_inferences.obo	(working copy)
@@ -24814,6 +24814,11 @@
 is_a: GO:0048856 {is_inferred="true"} ! anatomical structure development
 
 [Term]
+id: GO:0032839 ! dendrite cytoplasm
+is_a: GO:0032838 {is_inferred="true"} ! cell projection cytoplasm
+is_a: GO:0097458 {is_inferred="true"} ! neuron part
+
+[Term]
 id: GO:0032847 ! regulation of cellular pH reduction
 is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
 is_a: GO:0051453 {is_inferred="true"} ! regulation of intracellular pH
@@ -49279,6 +49284,11 @@
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
 
 [Term]
+id: GO:0061846 ! dendritic spine cytoplasm
+is_a: GO:0032839 {is_inferred="true"} ! dendrite cytoplasm
+is_a: GO:0044456 {is_inferred="true"} ! synapse part
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
------------------------------------------------------------------------
r38441 | dph | 2017-01-27 12:47:13 -0800 (Fri, 27 Jan 2017) | 3 lines

GH12964-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38441)
+++ go_inferences.obo	(working copy)
@@ -27983,10 +27983,6 @@
 is_a: GO:0033365 {is_inferred="true"} ! protein localization to organelle
 
 [Term]
-id: GO:0034506 ! chromosome, centromeric core domain
-is_a: GO:0000775 {is_inferred="true"} ! chromosome, centromeric region
-
-[Term]
 id: GO:0034507 ! chromosome, centromeric outer repeat region
 is_a: GO:0098687 {is_inferred="true"} ! chromosomal region
 
@@ -49279,6 +49275,10 @@
 is_a: GO:0051179 {is_inferred="true"} ! localization
 
 [Term]
+id: GO:0061845 ! neuron projection branch point
+is_a: GO:0097458 {is_inferred="true"} ! neuron part
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
@@ -89664,10 +89664,6 @@
 is_a: GO:0034504 {is_inferred="true"} ! protein localization to nucleus
 
 [Term]
-id: GO:1990033 ! dendritic branch point
-is_a: GO:0097458 {is_inferred="true"} ! neuron part
-
-[Term]
 id: GO:1990034 ! calcium ion export from cell
 is_a: GO:1901660 {is_inferred="true"} ! calcium ion export
 
------------------------------------------------------------------------
r38439 | dph | 2017-01-27 12:29:21 -0800 (Fri, 27 Jan 2017) | 2 lines

GH12961-closed

changes in entailments

------------------------------------------------------------------------
r38437 | dph | 2017-01-27 12:10:49 -0800 (Fri, 27 Jan 2017) | 2 lines

GH12957-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38437)
+++ go_inferences.obo	(working copy)
@@ -49270,7 +49270,7 @@
 is_a: GO:0044427 {is_inferred="true"} ! chromosomal part
 
 [Term]
-id: GO:0061841 ! high affinity iron exporter complex
+id: GO:0061841 ! high-affinity iron exporter complex
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 is_a: GO:1902495 {is_inferred="true"} ! transmembrane transporter complex
 
------------------------------------------------------------------------
r38434 | termgenie | 2017-01-27 11:47:49 -0800 (Fri, 27 Jan 2017) | 4 lines

TermGenie commit for user: slaulederkind reviewed by ukemi

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38434)
+++ go_inferences.obo	(working copy)
@@ -89602,6 +89602,10 @@
 is_a: GO:1990204 {is_inferred="true"} ! oxidoreductase complex
 
 [Term]
+id: GO:1905863 ! invadopodium organization
+is_a: GO:0030030 {is_inferred="true"} ! cell projection organization
+
+[Term]
 id: GO:1905864 ! regulation of ATG1/ULK1 kinase complex assembly
 is_a: GO:0043254 {is_inferred="true"} ! regulation of protein complex assembly
 
@@ -89616,6 +89620,38 @@
 is_a: GO:1905864 {is_inferred="true"} ! regulation of ATG1/ULK1 kinase complex assembly
 
 [Term]
+id: GO:1905867 ! epididymis development
+is_a: GO:0048608 {is_inferred="true"} ! reproductive structure development
+
+[Term]
+id: GO:1905868 ! regulation of 3'-UTR-mediated mRNA stabilization
+is_a: GO:0043488 {is_inferred="true"} ! regulation of mRNA stability
+
+[Term]
+id: GO:1905869 ! negative regulation of 3'-UTR-mediated mRNA stabilization
+is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
+is_a: GO:1905868 {is_inferred="true"} ! regulation of 3'-UTR-mediated mRNA stabilization
+
+[Term]
+id: GO:1905870 ! positive regulation of 3'-UTR-mediated mRNA stabilization
+is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
+is_a: GO:1905868 {is_inferred="true"} ! regulation of 3'-UTR-mediated mRNA stabilization
+
+[Term]
+id: GO:1905871 ! regulation of protein localization to cell leading edge
+is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
+
+[Term]
+id: GO:1905872 ! negative regulation of protein localization to cell leading edge
+is_a: GO:1903828 {is_inferred="true"} ! negative regulation of cellular protein localization
+is_a: GO:1905871 {is_inferred="true"} ! regulation of protein localization to cell leading edge
+
+[Term]
+id: GO:1905873 ! positive regulation of protein localization to cell leading edge
+is_a: GO:1903829 {is_inferred="true"} ! positive regulation of cellular protein localization
+is_a: GO:1905871 {is_inferred="true"} ! regulation of protein localization to cell leading edge
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r38424 | dph | 2017-01-26 12:48:48 -0800 (Thu, 26 Jan 2017) | 2 lines

GH12960-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38424)
+++ go_inferences.obo	(working copy)
@@ -44656,6 +44656,7 @@
 [Term]
 id: GO:0051642 ! centrosome localization
 is_a: GO:0051640 {is_inferred="true"} ! organelle localization
+is_a: GO:0061842 {is_inferred="true"} ! microtubule organizing center localization
 
 [Term]
 id: GO:0051644 ! plastid localization
@@ -49274,6 +49275,10 @@
 is_a: GO:1902495 {is_inferred="true"} ! transmembrane transporter complex
 
 [Term]
+id: GO:0061842 ! microtubule organizing center localization
+is_a: GO:0051179 {is_inferred="true"} ! localization
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
@@ -50513,6 +50518,10 @@
 is_a: GO:0070629 {is_inferred="true"} ! (1->4)-alpha-glucan metabolic process
 
 [Term]
+id: GO:0070631 ! spindle pole body localization
+is_a: GO:0061842 {is_inferred="true"} ! microtubule organizing center localization
+
+[Term]
 id: GO:0070632 ! establishment of spindle pole body localization
 is_a: GO:0070631 {is_inferred="true"} ! spindle pole body localization
 
------------------------------------------------------------------------
r38421 | dph | 2017-01-26 11:58:40 -0800 (Thu, 26 Jan 2017) | 2 lines

A whole bunch of iron transport edits and additions. GH12957-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38421)
+++ go_inferences.obo	(working copy)
@@ -26614,6 +26614,7 @@
 [Term]
 id: GO:0033573 ! high-affinity iron permease complex
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
+is_a: GO:1902495 {is_inferred="true"} ! transmembrane transporter complex
 
 [Term]
 id: GO:0033574 ! response to testosterone
@@ -27983,7 +27984,7 @@
 
 [Term]
 id: GO:0034506 ! chromosome, centromeric core domain
-is_a: GO:0098687 {is_inferred="true"} ! chromosomal region
+is_a: GO:0000775 {is_inferred="true"} ! chromosome, centromeric region
 
 [Term]
 id: GO:0034507 ! chromosome, centromeric outer repeat region
@@ -49268,6 +49269,11 @@
 is_a: GO:0044427 {is_inferred="true"} ! chromosomal part
 
 [Term]
+id: GO:0061841 ! high affinity iron exporter complex
+is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
+is_a: GO:1902495 {is_inferred="true"} ! transmembrane transporter complex
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
@@ -97803,6 +97809,18 @@
 is_a: CHEBI:36080 {is_inferred="true"} ! protein
 
 [Term]
+id: SO:0000651 ! large_subunit_rRNA
+is_a: CHEBI:18111 {is_inferred="true"} ! ribosomal RNA
+
+[Term]
+id: SO:0000862 ! capped_mRNA
+is_a: CHEBI:33699 {is_inferred="true"} ! messenger RNA
+
+[Term]
+id: SO:0000871 ! polyadenylated_mRNA
+is_a: CHEBI:33699 {is_inferred="true"} ! messenger RNA
+
+[Term]
 id: UBERON:0001289 ! descending limb of loop of Henle
 is_a: UBERON:0004810 {is_inferred="true"} ! nephron tubule epithelium
 
------------------------------------------------------------------------
r38408 | termgenie | 2017-01-26 05:27:24 -0800 (Thu, 26 Jan 2017) | 4 lines

TermGenie commit for user: paolaroncaglia reviewed by paolaroncaglia

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38408)
+++ go_inferences.obo	(working copy)
@@ -89587,6 +89587,20 @@
 is_a: GO:1990204 {is_inferred="true"} ! oxidoreductase complex
 
 [Term]
+id: GO:1905864 ! regulation of ATG1/ULK1 kinase complex assembly
+is_a: GO:0043254 {is_inferred="true"} ! regulation of protein complex assembly
+
+[Term]
+id: GO:1905865 ! negative regulation of ATG1/ULK1 kinase complex assembly
+is_a: GO:0031333 {is_inferred="true"} ! negative regulation of protein complex assembly
+is_a: GO:1905864 {is_inferred="true"} ! regulation of ATG1/ULK1 kinase complex assembly
+
+[Term]
+id: GO:1905866 ! positive regulation of ATG1/ULK1 kinase complex assembly
+is_a: GO:0031334 {is_inferred="true"} ! positive regulation of protein complex assembly
+is_a: GO:1905864 {is_inferred="true"} ! regulation of ATG1/ULK1 kinase complex assembly
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r38405 | dph | 2017-01-25 09:57:04 -0800 (Wed, 25 Jan 2017) | 2 lines

Edits to N-glycan trimming and some other glycoprotein processing terms. GH12913-closed

changes in entailments

------------------------------------------------------------------------
r38403 | cjm | 2017-01-25 08:27:36 -0800 (Wed, 25 Jan 2017) | 1 line

melanosome part-of melanocyte, https://github.com/geneontology/go-ontology/issues/12699

changes in entailments

------------------------------------------------------------------------
r38400 | paola | 2017-01-25 07:44:45 -0800 (Wed, 25 Jan 2017) | 3 lines

GH membrane tubulation/curvature #12387 - work in progress - see ticket for details

changes in entailments

------------------------------------------------------------------------
r38397 | mcourtot | 2017-01-25 07:01:31 -0800 (Wed, 25 Jan 2017) | 1 line

merged in  regulation terms as per https://github.com/geneontology/go-ontology/issues/12771 

changes in entailments

------------------------------------------------------------------------
r38396 | termgenie | 2017-01-25 06:58:54 -0800 (Wed, 25 Jan 2017) | 2 lines

TermGenie commit for user: bmeldal reviewed by ukemi

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38396)
+++ go_inferences.obo	(working copy)
@@ -89582,6 +89582,11 @@
 is_a: GO:0097435 {is_inferred="true"} ! supramolecular fiber organization
 
 [Term]
+id: GO:1905862 ! ferroxidase complex
+is_a: GO:0043234 {is_inferred="true"} ! protein complex
+is_a: GO:1990204 {is_inferred="true"} ! oxidoreductase complex
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r38393 | mcourtot | 2017-01-25 06:48:45 -0800 (Wed, 25 Jan 2017) | 1 line

merged in positive regulation terms as per https://github.com/geneontology/go-ontology/issues/12771

changes in entailments

------------------------------------------------------------------------
r38387 | mcourtot | 2017-01-25 06:07:52 -0800 (Wed, 25 Jan 2017) | 1 line

 Closes https://github.com/geneontology/go-ontology/issues/12727. Updated cytolysis by virus of host cell to be part_of viral release from host cell

changes in entailments

------------------------------------------------------------------------
r38384 | dph | 2017-01-25 05:26:39 -0800 (Wed, 25 Jan 2017) | 2 lines

GH12500-closed. Added gluconate pathway as a related synonym to the Entner-Doudoroff Pathway.

changes in entailments

------------------------------------------------------------------------
r38381 | paola | 2017-01-25 00:38:07 -0800 (Wed, 25 Jan 2017) | 3 lines

For cilia project: added missing dbxref GOC:cilia to 13 selected terms

changes in entailments

------------------------------------------------------------------------
r38381 | paola | 2017-01-25 00:38:07 -0800 (Wed, 25 Jan 2017) | 3 lines

For cilia project: added missing dbxref GOC:cilia to 13 selected terms

changes in entailments

------------------------------------------------------------------------
r38374 | dph | 2017-01-24 11:09:18 -0800 (Tue, 24 Jan 2017) | 2 lines

GH12951-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38374)
+++ go_inferences.obo	(working copy)
@@ -54437,10 +54437,6 @@
 is_a: GO:1904019 {is_inferred="true"} ! epithelial cell apoptotic process
 
 [Term]
-id: GO:0072588 ! box H/ACA RNP complex
-is_a: GO:0044428 {is_inferred="true"} ! nuclear part
-
-[Term]
 id: GO:0072589 ! box H/ACA scaRNP complex
 is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
 
@@ -57654,6 +57650,10 @@
 is_a: GO:0008033 {is_inferred="true"} ! tRNA processing
 
 [Term]
+id: GO:0090661 ! box H/ACA telomerase RNP complex
+is_a: GO:0044428 {is_inferred="true"} ! nuclear part
+
+[Term]
 id: GO:0090662 ! ATP hydrolysis coupled transmembrane transport
 is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
 
------------------------------------------------------------------------
r38372 | dph | 2017-01-24 11:00:45 -0800 (Tue, 24 Jan 2017) | 2 lines

GH12952-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38372)
+++ go_inferences.obo	(working copy)
@@ -49264,6 +49264,10 @@
 is_a: GO:1902414 {is_inferred="true"} ! protein localization to cell junction
 
 [Term]
+id: GO:0061838 ! CENP-T-W-S-X complex
+is_a: GO:0044427 {is_inferred="true"} ! chromosomal part
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
------------------------------------------------------------------------
r38370 | paola | 2017-01-24 07:57:27 -0800 (Tue, 24 Jan 2017) | 3 lines

GH GO and vesicle nomenclature #11504 - work in progress - added has_parts to ‘ribonucleoprotein complex’

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38370)
+++ go_inferences.obo	(working copy)
@@ -6922,7 +6922,6 @@
 
 [Term]
 id: GO:0006608 ! snRNP protein import into nucleus
-is_a: GO:0006606 {is_inferred="true"} ! protein import into nucleus
 is_a: GO:0071167 {is_inferred="true"} ! ribonucleoprotein complex import into nucleus
 
 [Term]
@@ -12603,6 +12602,7 @@
 [Term]
 id: GO:0010793 ! regulation of mRNA export from nucleus
 is_a: GO:0010468 {is_inferred="true"} ! regulation of gene expression
+is_a: GO:0046825 {is_inferred="true"} ! regulation of protein export from nucleus
 is_a: GO:0046831 {is_inferred="true"} ! regulation of RNA export from nucleus
 is_a: GO:2000197 {is_inferred="true"} ! regulation of ribonucleoprotein complex localization
 
@@ -26880,11 +26880,13 @@
 
 [Term]
 id: GO:0033750 ! ribosome localization
+is_a: GO:0008104 {is_inferred="true"} ! protein localization
 is_a: GO:0051640 {is_inferred="true"} ! organelle localization
 
 [Term]
 id: GO:0033753 ! establishment of ribosome localization
 is_a: GO:0033750 {is_inferred="true"} ! ribosome localization
+is_a: GO:0045184 {is_inferred="true"} ! establishment of protein localization
 
 [Term]
 id: GO:0033762 ! response to glucagon
@@ -51605,7 +51607,8 @@
 
 [Term]
 id: GO:0071167 ! ribonucleoprotein complex import into nucleus
-is_a: GO:0051170 {is_inferred="true"} ! nuclear import
+is_a: GO:0006404 {is_inferred="true"} ! RNA import into nucleus
+is_a: GO:0006606 {is_inferred="true"} ! protein import into nucleus
 
 [Term]
 id: GO:0071169 ! establishment of protein localization to chromatin
@@ -52430,7 +52433,8 @@
 
 [Term]
 id: GO:0071426 ! ribonucleoprotein complex export from nucleus
-is_a: GO:0051168 {is_inferred="true"} ! nuclear export
+is_a: GO:0006405 {is_inferred="true"} ! RNA export from nucleus
+is_a: GO:0006611 {is_inferred="true"} ! protein export from nucleus
 
 [Term]
 id: GO:0071432 ! peptide mating pheromone maturation involved in conjugation with cellular fusion
@@ -59589,7 +59593,9 @@
 
 [Term]
 id: GO:0098961 ! dendritic transport of ribonucleoprotein complex
+is_a: GO:0050658 {is_inferred="true"} ! RNA transport
 is_a: GO:0098935 {is_inferred="true"} ! dendritic transport
+is_a: GO:0099640 {is_inferred="true"} ! axo-dendritic protein transport
 
 [Term]
 id: GO:0098962 ! regulation of postsynaptic neurotransmitter receptor activity
@@ -59601,6 +59607,7 @@
 
 [Term]
 id: GO:0098964 ! anterograde dendritic transport of messenger ribonucleoprotein complex
+is_a: GO:0035418 {is_inferred="true"} ! protein localization to synapse
 is_a: GO:0098937 {is_inferred="true"} ! anterograde dendritic transport
 is_a: GO:0098963 {is_inferred="true"} ! dendritic transport of messenger ribonucleoprotein complex
 
@@ -59981,12 +59988,14 @@
 
 [Term]
 id: GO:0099087 ! anterograde axonal transport of messenger ribonucleoprotein complex
-is_a: GO:0008089 {is_inferred="true"} ! anterograde axonal transport
 is_a: GO:0099088 {is_inferred="true"} ! axonal transport of messenger ribonucleoprotein complex
+is_a: GO:0099641 {is_inferred="true"} ! anterograde axonal protein transport
 
 [Term]
 id: GO:0099088 ! axonal transport of messenger ribonucleoprotein complex
+is_a: GO:0050658 {is_inferred="true"} ! RNA transport
 is_a: GO:0098930 {is_inferred="true"} ! axonal transport
+is_a: GO:0099640 {is_inferred="true"} ! axo-dendritic protein transport
 
 [Term]
 id: GO:0099089 ! establishment of endoplasmic reticulum localization to postsynapse
@@ -91550,13 +91559,15 @@
 
 [Term]
 id: GO:2000200 ! regulation of ribosomal subunit export from nucleus
-is_a: GO:0046822 {is_inferred="true"} ! regulation of nucleocytoplasmic transport
+is_a: GO:0046825 {is_inferred="true"} ! regulation of protein export from nucleus
+is_a: GO:0046831 {is_inferred="true"} ! regulation of RNA export from nucleus
 is_a: GO:0090069 {is_inferred="true"} ! regulation of ribosome biogenesis
 is_a: GO:2000197 {is_inferred="true"} ! regulation of ribonucleoprotein complex localization
 
 [Term]
 id: GO:2000201 ! negative regulation of ribosomal subunit export from nucleus
-is_a: GO:0046823 {is_inferred="true"} ! negative regulation of nucleocytoplasmic transport
+is_a: GO:0046826 {is_inferred="true"} ! negative regulation of protein export from nucleus
+is_a: GO:0046832 {is_inferred="true"} ! negative regulation of RNA export from nucleus
 is_a: GO:0090071 {is_inferred="true"} ! negative regulation of ribosome biogenesis
 is_a: GO:2000198 {is_inferred="true"} ! negative regulation of ribonucleoprotein complex localization
 is_a: GO:2000200 {is_inferred="true"} ! regulation of ribosomal subunit export from nucleus
@@ -91563,7 +91574,8 @@
 
 [Term]
 id: GO:2000202 ! positive regulation of ribosomal subunit export from nucleus
-is_a: GO:0046824 {is_inferred="true"} ! positive regulation of nucleocytoplasmic transport
+is_a: GO:0046827 {is_inferred="true"} ! positive regulation of protein export from nucleus
+is_a: GO:0046833 {is_inferred="true"} ! positive regulation of RNA export from nucleus
 is_a: GO:0090070 {is_inferred="true"} ! positive regulation of ribosome biogenesis
 is_a: GO:2000199 {is_inferred="true"} ! positive regulation of ribonucleoprotein complex localization
 is_a: GO:2000200 {is_inferred="true"} ! regulation of ribosomal subunit export from nucleus
@@ -91737,11 +91749,13 @@
 
 [Term]
 id: GO:2000238 ! regulation of tRNA export from nucleus
+is_a: GO:0046825 {is_inferred="true"} ! regulation of protein export from nucleus
 is_a: GO:0046831 {is_inferred="true"} ! regulation of RNA export from nucleus
 is_a: GO:2000197 {is_inferred="true"} ! regulation of ribonucleoprotein complex localization
 
 [Term]
 id: GO:2000239 ! negative regulation of tRNA export from nucleus
+is_a: GO:0046826 {is_inferred="true"} ! negative regulation of protein export from nucleus
 is_a: GO:0046832 {is_inferred="true"} ! negative regulation of RNA export from nucleus
 is_a: GO:2000198 {is_inferred="true"} ! negative regulation of ribonucleoprotein complex localization
 is_a: GO:2000238 {is_inferred="true"} ! regulation of tRNA export from nucleus
@@ -91748,6 +91762,7 @@
 
 [Term]
 id: GO:2000240 ! positive regulation of tRNA export from nucleus
+is_a: GO:0046827 {is_inferred="true"} ! positive regulation of protein export from nucleus
 is_a: GO:0046833 {is_inferred="true"} ! positive regulation of RNA export from nucleus
 is_a: GO:2000199 {is_inferred="true"} ! positive regulation of ribonucleoprotein complex localization
 is_a: GO:2000238 {is_inferred="true"} ! regulation of tRNA export from nucleus
------------------------------------------------------------------------
r38367 | dph | 2017-01-24 06:54:39 -0800 (Tue, 24 Jan 2017) | 2 lines

GH12949-closed

changes in entailments

------------------------------------------------------------------------
r38361 | paola | 2017-01-24 03:46:55 -0800 (Tue, 24 Jan 2017) | 3 lines

GH GO:0003729 mRNA binding is currently child of poly(A) RNA binding #11022 - work in progress - merged ‘poly(A) RNA binding’ into ‘RNA binding’

changes in entailments

------------------------------------------------------------------------
r38359 | paola | 2017-01-24 03:39:08 -0800 (Tue, 24 Jan 2017) | 3 lines

GH GO:0003729 mRNA binding is currently child of poly(A) RNA binding #11022 - work in progress - moved ‘mRNA binding’ from under ‘poly(A) RNA binding’ to ‘RNA binding’

changes in entailments

------------------------------------------------------------------------
r38357 | paola | 2017-01-24 02:27:23 -0800 (Tue, 24 Jan 2017) | 3 lines

Added GO:0097752 ‘regulation of DNA stability’ needed for an EFO mapping

changes in entailments

------------------------------------------------------------------------
r38352 | termgenie | 2017-01-23 10:02:41 -0800 (Mon, 23 Jan 2017) | 2 lines

TermGenie commit for user: ukemi reviewed by ukemi

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38352)
+++ go_inferences.obo	(working copy)
@@ -89504,6 +89504,71 @@
 is_a: GO:1905846 {is_inferred="true"} ! regulation of cellular response to oxidopamine
 
 [Term]
+id: GO:1905849 ! negative regulation of forward locomotion
+is_a: GO:0040013 {is_inferred="true"} ! negative regulation of locomotion
+is_a: GO:0043059 {is_inferred="true"} ! regulation of forward locomotion
+
+[Term]
+id: GO:1905850 ! positive regulation of forward locomotion
+is_a: GO:0040017 {is_inferred="true"} ! positive regulation of locomotion
+is_a: GO:0043059 {is_inferred="true"} ! regulation of forward locomotion
+
+[Term]
+id: GO:1905851 ! negative regulation of backward locomotion
+is_a: GO:0040013 {is_inferred="true"} ! negative regulation of locomotion
+is_a: GO:0043058 {is_inferred="true"} ! regulation of backward locomotion
+
+[Term]
+id: GO:1905852 ! positive regulation of backward locomotion
+is_a: GO:0040017 {is_inferred="true"} ! positive regulation of locomotion
+is_a: GO:0043058 {is_inferred="true"} ! regulation of backward locomotion
+
+[Term]
+id: GO:1905853 ! regulation of heparan sulfate binding
+is_a: GO:0051098 {is_inferred="true"} ! regulation of binding
+
+[Term]
+id: GO:1905854 ! negative regulation of heparan sulfate binding
+is_a: GO:0051100 {is_inferred="true"} ! negative regulation of binding
+is_a: GO:1905853 {is_inferred="true"} ! regulation of heparan sulfate binding
+
+[Term]
+id: GO:1905855 ! positive regulation of heparan sulfate binding
+is_a: GO:0051099 {is_inferred="true"} ! positive regulation of binding
+is_a: GO:1905853 {is_inferred="true"} ! regulation of heparan sulfate binding
+
+[Term]
+id: GO:1905856 ! negative regulation of pentose-phosphate shunt
+is_a: GO:0043456 {is_inferred="true"} ! regulation of pentose-phosphate shunt
+is_a: GO:0045980 {is_inferred="true"} ! negative regulation of nucleotide metabolic process
+is_a: GO:0051198 {is_inferred="true"} ! negative regulation of coenzyme metabolic process
+
+[Term]
+id: GO:1905857 ! positive regulation of pentose-phosphate shunt
+is_a: GO:0043456 {is_inferred="true"} ! regulation of pentose-phosphate shunt
+is_a: GO:0045981 {is_inferred="true"} ! positive regulation of nucleotide metabolic process
+is_a: GO:0051197 {is_inferred="true"} ! positive regulation of coenzyme metabolic process
+
+[Term]
+id: GO:1905858 ! regulation of heparan sulfate proteoglycan binding
+is_a: GO:0043393 {is_inferred="true"} ! regulation of protein binding
+
+[Term]
+id: GO:1905859 ! negative regulation of heparan sulfate proteoglycan binding
+is_a: GO:0032091 {is_inferred="true"} ! negative regulation of protein binding
+is_a: GO:1905858 {is_inferred="true"} ! regulation of heparan sulfate proteoglycan binding
+
+[Term]
+id: GO:1905860 ! positive regulation of heparan sulfate proteoglycan binding
+is_a: GO:0032092 {is_inferred="true"} ! positive regulation of protein binding
+is_a: GO:1905858 {is_inferred="true"} ! regulation of heparan sulfate proteoglycan binding
+
+[Term]
+id: GO:1905861 ! intranuclear rod assembly
+is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
+is_a: GO:0097435 {is_inferred="true"} ! supramolecular fiber organization
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r38308 | hjd | 2017-01-20 12:31:56 -0800 (Fri, 20 Jan 2017) | 2 lines

fixed a dup name that slipped by me

changes in entailments

------------------------------------------------------------------------
r38302 | dph | 2017-01-20 11:51:04 -0800 (Fri, 20 Jan 2017) | 2 lines

GH12932-closed

changes in entailments

------------------------------------------------------------------------
r38300 | dph | 2017-01-20 09:48:08 -0800 (Fri, 20 Jan 2017) | 2 lines

Very large and weird diff, but just made a single change to a logical def. GH12922-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38300)
+++ go_inferences.obo	(working copy)
@@ -4745,10 +4745,6 @@
 is_a: GO:0015179 {is_inferred="true"} ! L-amino acid transmembrane transporter activity
 
 [Term]
-id: GO:0005315 ! inorganic phosphate transmembrane transporter activity
-is_a: GO:1901677 {is_inferred="true"} ! phosphate transmembrane transporter activity
-
-[Term]
 id: GO:0005324 ! long-chain fatty acid transporter activity
 is_a: GO:0015245 {is_inferred="true"} ! fatty acid transporter activity
 
@@ -13958,6 +13954,10 @@
 is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 
 [Term]
+id: GO:0015114 ! phosphate ion transmembrane transporter activity
+is_a: GO:1901677 {is_inferred="true"} ! phosphate transmembrane transporter activity
+
+[Term]
 id: GO:0015116 ! sulfate transmembrane transporter activity
 is_a: GO:1901682 {is_inferred="true"} ! sulfur compound transmembrane transporter activity
 
@@ -14454,10 +14454,6 @@
 is_a: GO:0015665 {is_inferred="true"} ! alcohol transmembrane transporter activity
 
 [Term]
-id: GO:0015317 ! phosphate:proton symporter activity
-is_a: GO:1901677 {is_inferred="true"} ! phosphate transmembrane transporter activity
-
-[Term]
 id: GO:0015325 ! acetyl-CoA:CoA antiporter activity
 is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:1901682 {is_inferred="true"} ! sulfur compound transmembrane transporter activity
@@ -14722,7 +14718,7 @@
 
 [Term]
 id: GO:0015605 ! organophosphate ester transmembrane transporter activity
-is_a: GO:1901677 {is_inferred="true"} ! phosphate transmembrane transporter activity
+is_a: GO:0022857 {is_inferred="true"} ! transmembrane transporter activity
 
 [Term]
 id: GO:0015606 ! spermidine transmembrane transporter activity
------------------------------------------------------------------------
r38298 | paola | 2017-01-20 08:41:28 -0800 (Fri, 20 Jan 2017) | 2 lines

Fixing more errors

changes in entailments

------------------------------------------------------------------------
r38294 | davidos | 2017-01-20 07:48:31 -0800 (Fri, 20 Jan 2017) | 1 line

More ViralZone terms (#11426). Changed colonial development to <socially cooperative development> (#12357). Fixed duplicated po/is_a edges on establishment of protein localization resulting from pro-chebi protein equivalence axioms.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38294)
+++ go_inferences.obo	(working copy)
@@ -58778,6 +58778,10 @@
 is_a: GO:0098956 {is_inferred="true"} ! intrinsic component of dense core granule membrane
 
 [Term]
+id: GO:0098676 ! modulation of host virulence by virus
+is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
+
+[Term]
 id: GO:0098700 ! neurotransmitter loading into synaptic vesicle
 is_a: GO:0006836 {is_inferred="true"} ! neurotransmitter transport
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
------------------------------------------------------------------------
r38292 | paola | 2017-01-20 07:20:59 -0800 (Fri, 20 Jan 2017) | 2 lines

GH parentage: GO:0039702 viral budding via host ESCRT complex #12254 - closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38292)
+++ go_inferences.obo	(working copy)
@@ -90228,9 +90228,10 @@
 is_a: GO:0045016 {is_inferred="true"} ! mitochondrial magnesium ion transport
 
 [Term]
-id: GO:1990621 ! Vps4-Vta1 complex
+id: GO:1990621 ! ESCRT IV complex
 is_a: GO:0044440 {is_inferred="true"} ! endosomal part
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
+is_a: GO:1904949 {is_inferred="true"} ! ATPase complex
 
 [Term]
 id: GO:1990629 ! phospholamban complex
------------------------------------------------------------------------
r38290 | paola | 2017-01-20 07:03:19 -0800 (Fri, 20 Jan 2017) | 2 lines

GH Difference between GO:0070840 and GO:0045502 #12133 - work in progress - merged 'dynein binding' into 'dynein complex binding'

changes in entailments

------------------------------------------------------------------------
r38288 | paola | 2017-01-20 06:41:53 -0800 (Fri, 20 Jan 2017) | 2 lines

GH Difference between GO:0070840 and GO:0045502 #12133 - work in progress - see ticket

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38288)
+++ go_inferences.obo	(working copy)
@@ -89462,11 +89462,11 @@
 
 [Term]
 id: GO:1905841 ! response to oxidopamine
-is_a: GO:0050896 {is_inferred="true"} ! response to stimulus
+is_a: GO:0071869 {is_inferred="true"} ! response to catecholamine
 
 [Term]
 id: GO:1905842 ! cellular response to oxidopamine
-is_a: GO:0070887 {is_inferred="true"} ! cellular response to chemical stimulus
+is_a: GO:0071870 {is_inferred="true"} ! cellular response to catecholamine stimulus
 is_a: GO:1905841 {is_inferred="true"} ! response to oxidopamine
 
 [Term]
------------------------------------------------------------------------
r38277 | hjd | 2017-01-19 12:00:34 -0800 (Thu, 19 Jan 2017) | 2 lines

removed synonym from stress granuale and added synonym for Flemming body (GH:12945)

changes in entailments

------------------------------------------------------------------------
r38267 | paola | 2017-01-19 08:03:20 -0800 (Thu, 19 Jan 2017) | 2 lines

Removed odd remark line

changes in entailments

------------------------------------------------------------------------
r38264 | termgenie | 2017-01-19 05:40:43 -0800 (Thu, 19 Jan 2017) | 4 lines

TermGenie commit for user: rozaru reviewed by ukemi

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38264)
+++ go_inferences.obo	(working copy)
@@ -85889,6 +85889,7 @@
 id: GO:1905092 ! response to diosgenin
 is_a: GO:0036314 {is_inferred="true"} ! response to sterol
 is_a: GO:0097305 {is_inferred="true"} ! response to alcohol
+is_a: GO:1905836 {is_inferred="true"} ! response to triterpenoid
 
 [Term]
 id: GO:1905093 ! cellular response to diosgenin
@@ -85895,6 +85896,7 @@
 is_a: GO:0036315 {is_inferred="true"} ! cellular response to sterol
 is_a: GO:0097306 {is_inferred="true"} ! cellular response to alcohol
 is_a: GO:1905092 {is_inferred="true"} ! response to diosgenin
+is_a: GO:1905837 {is_inferred="true"} ! cellular response to triterpenoid
 
 [Term]
 id: GO:1905094 ! regulation of apolipoprotein A-I-mediated signaling pathway
@@ -89422,6 +89424,43 @@
 is_a: GO:0031115 {is_inferred="true"} ! negative regulation of microtubule polymerization
 
 [Term]
+id: GO:1905834 ! response to pyrimidine ribonucleotide
+is_a: GO:0010243 {is_inferred="true"} ! response to organonitrogen compound
+is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
+is_a: GO:0046683 {is_inferred="true"} ! response to organophosphorus
+is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
+
+[Term]
+id: GO:1905835 ! cellular response to pyrimidine ribonucleotide
+is_a: GO:0071407 {is_inferred="true"} ! cellular response to organic cyclic compound
+is_a: GO:0071417 {is_inferred="true"} ! cellular response to organonitrogen compound
+is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
+is_a: GO:1905834 {is_inferred="true"} ! response to pyrimidine ribonucleotide
+
+[Term]
+id: GO:1905836 ! response to triterpenoid
+is_a: GO:0033993 {is_inferred="true"} ! response to lipid
+
+[Term]
+id: GO:1905837 ! cellular response to triterpenoid
+is_a: GO:0071396 {is_inferred="true"} ! cellular response to lipid
+is_a: GO:1905836 {is_inferred="true"} ! response to triterpenoid
+
+[Term]
+id: GO:1905838 ! regulation of telomeric D-loop disassembly
+is_a: GO:1904533 {is_inferred="true"} ! regulation of telomeric loop disassembly
+
+[Term]
+id: GO:1905839 ! negative regulation of telomeric D-loop disassembly
+is_a: GO:1904534 {is_inferred="true"} ! negative regulation of telomeric loop disassembly
+is_a: GO:1905838 {is_inferred="true"} ! regulation of telomeric D-loop disassembly
+
+[Term]
+id: GO:1905840 ! positive regulation of telomeric D-loop disassembly
+is_a: GO:1904535 {is_inferred="true"} ! positive regulation of telomeric loop disassembly
+is_a: GO:1905838 {is_inferred="true"} ! regulation of telomeric D-loop disassembly
+
+[Term]
 id: GO:1905841 ! response to oxidopamine
 is_a: GO:0050896 {is_inferred="true"} ! response to stimulus
 
@@ -89431,6 +89470,40 @@
 is_a: GO:1905841 {is_inferred="true"} ! response to oxidopamine
 
 [Term]
+id: GO:1905843 ! regulation of cellular response to gamma radiation
+is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
+is_a: GO:2001228 {is_inferred="true"} ! regulation of response to gamma radiation
+
+[Term]
+id: GO:1905844 ! negative regulation of cellular response to gamma radiation
+is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
+is_a: GO:1905843 {is_inferred="true"} ! regulation of cellular response to gamma radiation
+is_a: GO:2001229 {is_inferred="true"} ! negative regulation of response to gamma radiation
+
+[Term]
+id: GO:1905845 ! positive regulation of cellular response to gamma radiation
+is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
+is_a: GO:1905843 {is_inferred="true"} ! regulation of cellular response to gamma radiation
+is_a: GO:2001230 {is_inferred="true"} ! positive regulation of response to gamma radiation
+
+[Term]
+id: GO:1905846 ! regulation of cellular response to oxidopamine
+is_a: GO:0048583 {is_inferred="true"} ! regulation of response to stimulus
+is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
+
+[Term]
+id: GO:1905847 ! negative regulation of cellular response to oxidopamine
+is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
+is_a: GO:0048585 {is_inferred="true"} ! negative regulation of response to stimulus
+is_a: GO:1905846 {is_inferred="true"} ! regulation of cellular response to oxidopamine
+
+[Term]
+id: GO:1905848 ! positive regulation of cellular response to oxidopamine
+is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
+is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
+is_a: GO:1905846 {is_inferred="true"} ! regulation of cellular response to oxidopamine
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r38258 | paola | 2017-01-19 04:12:04 -0800 (Thu, 19 Jan 2017) | 2 lines

For autophagy project: changed scope of some synonyms of 'autophagosome membrane disassembly'

changes in entailments

------------------------------------------------------------------------
r38256 | termgenie | 2017-01-19 01:53:14 -0800 (Thu, 19 Jan 2017) | 3 lines

TermGenie commit for user: paolaroncaglia reviewed by paolaroncaglia

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38256)
+++ go_inferences.obo	(working copy)
@@ -89422,6 +89422,15 @@
 is_a: GO:0031115 {is_inferred="true"} ! negative regulation of microtubule polymerization
 
 [Term]
+id: GO:1905841 ! response to oxidopamine
+is_a: GO:0050896 {is_inferred="true"} ! response to stimulus
+
+[Term]
+id: GO:1905842 ! cellular response to oxidopamine
+is_a: GO:0070887 {is_inferred="true"} ! cellular response to chemical stimulus
+is_a: GO:1905841 {is_inferred="true"} ! response to oxidopamine
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r38234 | dph | 2017-01-18 13:41:56 -0800 (Wed, 18 Jan 2017) | 2 lines

GH12930-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38234)
+++ go_inferences.obo	(working copy)
@@ -49262,6 +49262,10 @@
 is_a: GO:0035973 {is_inferred="true"} ! aggrephagy
 
 [Term]
+id: GO:0061833 ! protein localization to tricellular tight junction
+is_a: GO:1902414 {is_inferred="true"} ! protein localization to cell junction
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
------------------------------------------------------------------------
r38231 | dph | 2017-01-18 13:26:56 -0800 (Wed, 18 Jan 2017) | 2 lines

GH11908-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38231)
+++ go_inferences.obo	(working copy)
@@ -6933,7 +6933,6 @@
 id: GO:0006612 ! protein targeting to membrane
 is_a: GO:0006605 {is_inferred="true"} ! protein targeting
 is_a: GO:0090150 {is_inferred="true"} ! establishment of protein localization to membrane
-is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:0006622 ! protein targeting to lysosome
@@ -43586,6 +43585,7 @@
 [Term]
 id: GO:0051204 ! protein insertion into mitochondrial membrane
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
+is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 
 [Term]
 id: GO:0051206 ! silicate metabolic process
@@ -54469,15 +54469,16 @@
 is_a: GO:0051220 {is_inferred="true"} ! cytoplasmic sequestering of protein
 
 [Term]
-id: GO:0072657 ! protein localization to membrane
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
-
-[Term]
 id: GO:0072659 ! protein localization to plasma membrane
 is_a: GO:0072657 {is_inferred="true"} ! protein localization to membrane
+is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
 
 [Term]
+id: GO:0072661 ! protein targeting to plasma membrane
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
+
+[Term]
 id: GO:0072662 ! protein localization to peroxisome
 is_a: GO:0033365 {is_inferred="true"} ! protein localization to organelle
 
@@ -56436,6 +56437,7 @@
 id: GO:0090151 ! establishment of protein localization to mitochondrial membrane
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
 is_a: GO:0072655 {is_inferred="true"} ! establishment of protein localization to mitochondrion
+is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 
 [Term]
 id: GO:0090152 ! establishment of protein localization to mitochondrial membrane involved in mitochondrial fission
@@ -59230,7 +59232,6 @@
 
 [Term]
 id: GO:0098877 ! neurotransmitter receptor transport to plasma membrane
-is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
 is_a: GO:0090150 {is_inferred="true"} ! establishment of protein localization to membrane
 is_a: GO:0098876 {is_inferred="true"} ! vesicle-mediated transport to the plasma membrane
 is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
@@ -76208,6 +76209,7 @@
 
 [Term]
 id: GO:1903077 ! negative regulation of protein localization to plasma membrane
+is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:1903076 {is_inferred="true"} ! regulation of protein localization to plasma membrane
 is_a: GO:1904376 {is_inferred="true"} ! negative regulation of protein localization to cell periphery
 is_a: GO:1905476 {is_inferred="true"} ! negative regulation of protein localization to membrane
@@ -76214,6 +76216,7 @@
 
 [Term]
 id: GO:1903078 ! positive regulation of protein localization to plasma membrane
+is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 is_a: GO:1903076 {is_inferred="true"} ! regulation of protein localization to plasma membrane
 is_a: GO:1904377 {is_inferred="true"} ! positive regulation of protein localization to cell periphery
 is_a: GO:1905477 {is_inferred="true"} ! positive regulation of protein localization to membrane
@@ -87719,18 +87722,15 @@
 
 [Term]
 id: GO:1905475 ! regulation of protein localization to membrane
-is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
 
 [Term]
 id: GO:1905476 ! negative regulation of protein localization to membrane
-is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:1903828 {is_inferred="true"} ! negative regulation of cellular protein localization
 is_a: GO:1905475 {is_inferred="true"} ! regulation of protein localization to membrane
 
 [Term]
 id: GO:1905477 ! positive regulation of protein localization to membrane
-is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 is_a: GO:1903829 {is_inferred="true"} ! positive regulation of cellular protein localization
 is_a: GO:1905475 {is_inferred="true"} ! regulation of protein localization to membrane
 
------------------------------------------------------------------------
r38229 | dph | 2017-01-18 13:09:07 -0800 (Wed, 18 Jan 2017) | 2 lines

One last tweak to the logical definition of a regulation of mitophagy term.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38229)
+++ go_inferences.obo	(working copy)
@@ -58977,7 +58977,7 @@
 [Term]
 id: GO:0098779 ! positive regulation of macromitophagy in response to mitochondrial depolarization
 is_a: GO:1901526 {is_inferred="true"} ! positive regulation of macromitophagy
-is_a: GO:1904923 {is_inferred="true"} ! regulation of mitophagy in response to mitochondrial depolarization
+is_a: GO:1904925 {is_inferred="true"} ! positive regulation of mitophagy in response to mitochondrial depolarization
 
 [Term]
 id: GO:0098781 ! ncRNA transcription
@@ -85052,10 +85052,8 @@
 
 [Term]
 id: GO:1904925 ! positive regulation of mitophagy in response to mitochondrial depolarization
-is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
-is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
-is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
-is_a: GO:1901524 {is_inferred="true"} ! regulation of macromitophagy
+is_a: GO:1903599 {is_inferred="true"} ! positive regulation of mitophagy
+is_a: GO:1904923 {is_inferred="true"} ! regulation of mitophagy in response to mitochondrial depolarization
 
 [Term]
 id: GO:1904926 ! response to palmitoleic acid
@@ -85876,7 +85874,8 @@
 
 [Term]
 id: GO:1905091 ! positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
-is_a: GO:1904925 {is_inferred="true"} ! positive regulation of mitophagy in response to mitochondrial depolarization
+is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
+is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
 is_a: GO:1905089 {is_inferred="true"} ! regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
 
 [Term]
------------------------------------------------------------------------
r38227 | dph | 2017-01-18 12:57:42 -0800 (Wed, 18 Jan 2017) | 2 lines

Fixed duplicate name by replacing mitophagy with macromitophagy.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38227)
+++ go_inferences.obo	(working copy)
@@ -27611,6 +27611,11 @@
 is_a: GO:0051346 {is_inferred="true"} ! negative regulation of hydrolase activity
 
 [Term]
+id: GO:0034263 ! positive regulation of autophagy in response to ER overload
+is_a: GO:0006983 {is_inferred="true"} ! ER overload response
+is_a: GO:0010508 {is_inferred="true"} ! positive regulation of autophagy
+
+[Term]
 id: GO:0034264 ! isopentenyl adenine metabolic process
 is_a: GO:0072521 {is_inferred="true"} ! purine-containing compound metabolic process
 
@@ -58970,6 +58975,11 @@
 is_a: GO:0098776 {is_inferred="true"} ! protein transport across the cell outer membrane
 
 [Term]
+id: GO:0098779 ! positive regulation of macromitophagy in response to mitochondrial depolarization
+is_a: GO:1901526 {is_inferred="true"} ! positive regulation of macromitophagy
+is_a: GO:1904923 {is_inferred="true"} ! regulation of mitophagy in response to mitochondrial depolarization
+
+[Term]
 id: GO:0098781 ! ncRNA transcription
 is_a: GO:0034660 {is_inferred="true"} ! ncRNA metabolic process
 
@@ -85030,20 +85040,22 @@
 
 [Term]
 id: GO:1904923 ! regulation of mitophagy in response to mitochondrial depolarization
-is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
-is_a: GO:1901524 {is_inferred="true"} ! regulation of macromitophagy
+is_a: GO:0098780 {is_inferred="true"} ! response to mitochondrial depolarisation
+is_a: GO:1903146 {is_inferred="true"} ! regulation of mitophagy
 
 [Term]
 id: GO:1904924 ! negative regulation of mitophagy in response to mitochondrial depolarization
+is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
 is_a: GO:0048585 {is_inferred="true"} ! negative regulation of response to stimulus
-is_a: GO:1901525 {is_inferred="true"} ! negative regulation of macromitophagy
-is_a: GO:1904923 {is_inferred="true"} ! regulation of mitophagy in response to mitochondrial depolarization
+is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
+is_a: GO:1901524 {is_inferred="true"} ! regulation of macromitophagy
 
 [Term]
 id: GO:1904925 ! positive regulation of mitophagy in response to mitochondrial depolarization
+is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
 is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
-is_a: GO:1901526 {is_inferred="true"} ! positive regulation of macromitophagy
-is_a: GO:1904923 {is_inferred="true"} ! regulation of mitophagy in response to mitochondrial depolarization
+is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
+is_a: GO:1901524 {is_inferred="true"} ! regulation of macromitophagy
 
 [Term]
 id: GO:1904926 ! response to palmitoleic acid
@@ -85853,18 +85865,19 @@
 is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
 
 [Term]
-id: GO:1905089 ! regulation of parkin-mediated mitophagy in response to mitochondrial depolarization
-is_a: GO:1904923 {is_inferred="true"} ! regulation of mitophagy in response to mitochondrial depolarization
+id: GO:1905089 ! regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
+is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
+is_a: GO:1901524 {is_inferred="true"} ! regulation of macromitophagy
 
 [Term]
-id: GO:1905090 ! negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization
+id: GO:1905090 ! negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
 is_a: GO:1904924 {is_inferred="true"} ! negative regulation of mitophagy in response to mitochondrial depolarization
-is_a: GO:1905089 {is_inferred="true"} ! regulation of parkin-mediated mitophagy in response to mitochondrial depolarization
+is_a: GO:1905089 {is_inferred="true"} ! regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
 
 [Term]
-id: GO:1905091 ! positive regulation of parkin-mediated mitophagy in response to mitochondrial depolarization
+id: GO:1905091 ! positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
 is_a: GO:1904925 {is_inferred="true"} ! positive regulation of mitophagy in response to mitochondrial depolarization
-is_a: GO:1905089 {is_inferred="true"} ! regulation of parkin-mediated mitophagy in response to mitochondrial depolarization
+is_a: GO:1905089 {is_inferred="true"} ! regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
 
 [Term]
 id: GO:1905092 ! response to diosgenin
------------------------------------------------------------------------
r38223 | dph | 2017-01-18 10:21:52 -0800 (Wed, 18 Jan 2017) | 2 lines

GH12928-closed

changes in entailments

------------------------------------------------------------------------
r38221 | dph | 2017-01-18 10:12:15 -0800 (Wed, 18 Jan 2017) | 2 lines

GH12927-closed

changes in entailments

------------------------------------------------------------------------
r38219 | dph | 2017-01-18 09:31:40 -0800 (Wed, 18 Jan 2017) | 2 lines

GH12939-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38219)
+++ go_inferences.obo	(working copy)
@@ -84378,19 +84378,19 @@
 is_a: GO:1903436 {is_inferred="true"} ! regulation of mitotic cytokinetic process
 
 [Term]
-id: GO:1904790 ! regulation of telosome assembly
+id: GO:1904790 ! regulation of shelterin complex assembly
 is_a: GO:0033044 {is_inferred="true"} ! regulation of chromosome organization
 is_a: GO:0044087 {is_inferred="true"} ! regulation of cellular component biogenesis
 
 [Term]
-id: GO:1904791 ! negative regulation of telosome assembly
-is_a: GO:1904790 {is_inferred="true"} ! regulation of telosome assembly
+id: GO:1904791 ! negative regulation of shelterin complex assembly
+is_a: GO:1904790 {is_inferred="true"} ! regulation of shelterin complex assembly
 is_a: GO:2001251 {is_inferred="true"} ! negative regulation of chromosome organization
 
 [Term]
-id: GO:1904792 ! positive regulation of telosome assembly
+id: GO:1904792 ! positive regulation of shelterin complex assembly
 is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
-is_a: GO:1904790 {is_inferred="true"} ! regulation of telosome assembly
+is_a: GO:1904790 {is_inferred="true"} ! regulation of shelterin complex assembly
 is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
 
 [Term]
------------------------------------------------------------------------
r38215 | dph | 2017-01-18 09:18:49 -0800 (Wed, 18 Jan 2017) | 2 lines

GH12940-closed and GH12938-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38215)
+++ go_inferences.obo	(working copy)
@@ -84379,19 +84379,19 @@
 
 [Term]
 id: GO:1904790 ! regulation of telosome assembly
+is_a: GO:0033044 {is_inferred="true"} ! regulation of chromosome organization
 is_a: GO:0044087 {is_inferred="true"} ! regulation of cellular component biogenesis
-is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 
 [Term]
 id: GO:1904791 ! negative regulation of telosome assembly
-is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:1904790 {is_inferred="true"} ! regulation of telosome assembly
+is_a: GO:2001251 {is_inferred="true"} ! negative regulation of chromosome organization
 
 [Term]
 id: GO:1904792 ! positive regulation of telosome assembly
 is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
-is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 is_a: GO:1904790 {is_inferred="true"} ! regulation of telosome assembly
+is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
 
 [Term]
 id: GO:1904793 ! regulation of euchromatin binding
------------------------------------------------------------------------
r38131 | davidos | 2017-01-18 05:09:34 -0800 (Wed, 18 Jan 2017) | 14 lines

All edits are work described in or resulting from #12341 

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38131)
+++ go_inferences.obo	(working copy)
@@ -26,6 +26,14 @@
 is_a: GOCHE:37527 {is_inferred="true"} ! substance with acid chemical property
 
 [Term]
+id: CHEBI:17843 ! transfer RNA
+is_a: SO:0000655 {is_inferred="true"} ! ncRNA
+
+[Term]
+id: CHEBI:18111 ! ribosomal RNA
+is_a: SO:0000655 {is_inferred="true"} ! ncRNA
+
+[Term]
 id: CHEBI:18157 ! aerobactin
 is_a: GOCHE:24028 {is_inferred="true"} ! substance with iron(3+) chelator role
 
@@ -58,6 +66,10 @@
 is_a: GOCHE:37527 {is_inferred="true"} ! substance with acid chemical property
 
 [Term]
+id: CHEBI:29264 ! tRNA(Sec)
+is_a: SO:0000253 {is_inferred="true"} ! tRNA
+
+[Term]
 id: CHEBI:29669 ! pyochelin
 is_a: GOCHE:24028 {is_inferred="true"} ! substance with iron(3+) chelator role
 
@@ -66,6 +78,10 @@
 is_a: GOCHE:37527 {is_inferred="true"} ! substance with acid chemical property
 
 [Term]
+id: CHEBI:33699 ! messenger RNA
+is_a: SO:0000233 {is_inferred="true"} ! mature_transcript
+
+[Term]
 id: CHEBI:33837 ! conjugated protein
 is_a: PR:000000001 {is_inferred="true"} ! protein
 
@@ -560,6 +576,10 @@
 is_a: GO:0046872 {is_inferred="true"} ! metal ion binding
 
 [Term]
+id: GO:0000292 ! RNA fragment catabolic process
+is_a: GO:0006401 {is_inferred="true"} ! RNA catabolic process
+
+[Term]
 id: GO:0000295 ! adenine nucleotide transmembrane transporter activity
 is_a: GO:0015216 {is_inferred="true"} ! purine nucleotide transmembrane transporter activity
 
@@ -6441,6 +6461,11 @@
 is_a: GO:0006355 {is_inferred="true"} ! regulation of transcription, DNA-templated
 
 [Term]
+id: GO:0006379 ! mRNA cleavage
+is_a: GO:0016071 {is_inferred="true"} ! mRNA metabolic process
+is_a: GO:0090501 {is_inferred="true"} ! RNA phosphodiester bond hydrolysis
+
+[Term]
 id: GO:0006390 ! transcription from mitochondrial promoter
 is_a: GO:0000959 {is_inferred="true"} ! mitochondrial RNA metabolic process
 is_a: GO:0006351 {is_inferred="true"} ! transcription, DNA-templated
@@ -6459,6 +6484,10 @@
 is_a: GO:0006353 {is_inferred="true"} ! DNA-templated transcription, termination
 
 [Term]
+id: GO:0006399 ! tRNA metabolic process
+is_a: GO:0034660 {is_inferred="true"} ! ncRNA metabolic process
+
+[Term]
 id: GO:0006401 ! RNA catabolic process
 is_a: GO:0016070 {is_inferred="true"} ! RNA metabolic process
 is_a: GO:0034655 {is_inferred="true"} ! nucleobase-containing compound catabolic process
@@ -9778,6 +9807,7 @@
 
 [Term]
 id: GO:0009303 ! rRNA transcription
+is_a: GO:0016072 {is_inferred="true"} ! rRNA metabolic process
 is_a: GO:0098781 {is_inferred="true"} ! ncRNA transcription
 
 [Term]
@@ -11908,6 +11938,10 @@
 is_a: GO:0046717 {is_inferred="true"} ! acid secretion
 
 [Term]
+id: GO:0010587 ! miRNA catabolic process
+is_a: GO:0010586 {is_inferred="true"} ! miRNA metabolic process
+
+[Term]
 id: GO:0010588 ! cotyledon vascular tissue pattern formation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 
@@ -16042,12 +16076,36 @@
 is_a: GO:0016070 {is_inferred="true"} ! RNA metabolic process
 
 [Term]
+id: GO:0016072 ! rRNA metabolic process
+is_a: GO:0034660 {is_inferred="true"} ! ncRNA metabolic process
+
+[Term]
+id: GO:0016073 ! snRNA metabolic process
+is_a: GO:0034660 {is_inferred="true"} ! ncRNA metabolic process
+
+[Term]
+id: GO:0016074 ! snoRNA metabolic process
+is_a: GO:0034660 {is_inferred="true"} ! ncRNA metabolic process
+
+[Term]
 id: GO:0016075 ! rRNA catabolic process
 is_a: GO:0016072 {is_inferred="true"} ! rRNA metabolic process
+is_a: GO:0034661 {is_inferred="true"} ! ncRNA catabolic process
 
 [Term]
+id: GO:0016076 ! snRNA catabolic process
+is_a: GO:0016073 {is_inferred="true"} ! snRNA metabolic process
+is_a: GO:0034661 {is_inferred="true"} ! ncRNA catabolic process
+
+[Term]
+id: GO:0016077 ! snoRNA catabolic process
+is_a: GO:0016074 {is_inferred="true"} ! snoRNA metabolic process
+is_a: GO:0034661 {is_inferred="true"} ! ncRNA catabolic process
+
+[Term]
 id: GO:0016078 ! tRNA catabolic process
 is_a: GO:0006399 {is_inferred="true"} ! tRNA metabolic process
+is_a: GO:0034661 {is_inferred="true"} ! ncRNA catabolic process
 
 [Term]
 id: GO:0016079 ! synaptic vesicle exocytosis
@@ -16520,6 +16578,10 @@
 is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
 
 [Term]
+id: GO:0016556 ! mRNA modification
+is_a: GO:0016071 {is_inferred="true"} ! mRNA metabolic process
+
+[Term]
 id: GO:0016557 ! peroxisome membrane biogenesis
 is_a: GO:0044091 {is_inferred="true"} ! membrane biogenesis
 
@@ -28089,6 +28151,15 @@
 is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
 
 [Term]
+id: GO:0034660 ! ncRNA metabolic process
+is_a: GO:0016070 {is_inferred="true"} ! RNA metabolic process
+
+[Term]
+id: GO:0034661 ! ncRNA catabolic process
+is_a: GO:0006401 {is_inferred="true"} ! RNA catabolic process
+is_a: GO:0034660 {is_inferred="true"} ! ncRNA metabolic process
+
+[Term]
 id: GO:0034662 ! CFTR-NHERF-ezrin complex
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
@@ -30544,6 +30615,11 @@
 is_a: GO:0061062 {is_inferred="true"} ! regulation of nematode larval development
 
 [Term]
+id: GO:0040031 ! snRNA modification
+is_a: GO:0009451 {is_inferred="true"} ! RNA modification
+is_a: GO:0016073 {is_inferred="true"} ! snRNA metabolic process
+
+[Term]
 id: GO:0040035 ! hermaphrodite genitalia development
 is_a: GO:0008406 {is_inferred="true"} ! gonad development
 
@@ -32409,6 +32485,10 @@
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 
 [Term]
+id: GO:0042868 ! antisense RNA metabolic process
+is_a: GO:0034660 {is_inferred="true"} ! ncRNA metabolic process
+
+[Term]
 id: GO:0042869 ! aldarate transport
 is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
 is_a: GO:0008643 {is_inferred="true"} ! carbohydrate transport
@@ -32759,7 +32839,6 @@
 is_a: GO:0006893 {is_inferred="true"} ! Golgi to plasma membrane transport
 is_a: GO:0015031 {is_inferred="true"} ! protein transport
 is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
-is_a: GO:0072659 {is_inferred="true"} ! protein localization to plasma membrane
 is_a: GO:0090002 {is_inferred="true"} ! establishment of protein localization to plasma membrane
 
 [Term]
@@ -34821,7 +34900,8 @@
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
 [Term]
-id: GO:0044743 ! intracellular protein transmembrane import
+id: GO:0044743 ! protein transmembrane import into intracellular organelle
+is_a: GO:0072594 {is_inferred="true"} ! establishment of protein localization to organelle
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
@@ -34990,14 +35070,12 @@
 [Term]
 id: GO:0044861 ! protein transport into plasma membrane raft
 is_a: GO:0044860 {is_inferred="true"} ! protein localization to plasma membrane raft
-is_a: GO:0090002 {is_inferred="true"} ! establishment of protein localization to plasma membrane
-is_a: GO:0098876 {is_inferred="true"} ! vesicle-mediated transport to the plasma membrane
 
 [Term]
 id: GO:0044862 ! protein transport out of plasma membrane raft
-is_a: GO:0090002 {is_inferred="true"} ! establishment of protein localization to plasma membrane
-is_a: GO:0098876 {is_inferred="true"} ! vesicle-mediated transport to the plasma membrane
+is_a: GO:0090150 {is_inferred="true"} ! establishment of protein localization to membrane
 is_a: GO:0099632 {is_inferred="true"} ! protein transport within plasma membrane
+is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
 
 [Term]
 id: GO:0044866 ! modulation by host of viral exo-alpha-sialidase activity
@@ -35053,7 +35131,12 @@
 is_a: GO:0006605 {is_inferred="true"} ! protein targeting
 
 [Term]
+id: GO:0045037 ! protein import into chloroplast stroma
+is_a: GO:0044743 {is_inferred="true"} ! protein transmembrane import into intracellular organelle
+
+[Term]
 id: GO:0045039 ! protein import into mitochondrial inner membrane
+is_a: GO:0044743 {is_inferred="true"} ! protein transmembrane import into intracellular organelle
 is_a: GO:0090151 {is_inferred="true"} ! establishment of protein localization to mitochondrial membrane
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
@@ -50192,6 +50275,10 @@
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
 [Term]
+id: GO:0070525 ! tRNA threonylcarbamoyladenosine metabolic process
+is_a: GO:0016070 {is_inferred="true"} ! RNA metabolic process
+
+[Term]
 id: GO:0070538 ! oleic acid binding
 is_a: GO:0036041 {is_inferred="true"} ! long-chain fatty acid binding
 
@@ -54386,10 +54473,6 @@
 is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
 
 [Term]
-id: GO:0072661 ! protein targeting to plasma membrane
-is_a: GO:0098876 {is_inferred="true"} ! vesicle-mediated transport to the plasma membrane
-
-[Term]
 id: GO:0072662 ! protein localization to peroxisome
 is_a: GO:0033365 {is_inferred="true"} ! protein localization to organelle
 
@@ -55901,7 +55984,7 @@
 
 [Term]
 id: GO:0090002 ! establishment of protein localization to plasma membrane
-is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
+is_a: GO:0072659 {is_inferred="true"} ! protein localization to plasma membrane
 
 [Term]
 id: GO:0090003 ! regulation of establishment of protein localization to plasma membrane
@@ -58834,7 +58917,7 @@
 
 [Term]
 id: GO:0098737 ! protein insertion into plasma membrane
-is_a: GO:0090002 {is_inferred="true"} ! establishment of protein localization to plasma membrane
+is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
 
 [Term]
 id: GO:0098739 ! import across plasma membrane
@@ -58964,6 +59047,10 @@
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 
 [Term]
+id: GO:0098808 ! mRNA cap binding
+is_a: GO:0003729 {is_inferred="true"} ! mRNA binding
+
+[Term]
 id: GO:0098810 ! neurotransmitter reuptake
 is_a: GO:0001504 {is_inferred="true"} ! neurotransmitter uptake
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
@@ -58974,6 +59061,7 @@
 
 [Term]
 id: GO:0098812 ! nuclear rRNA polyadenylation involved in polyadenylation-dependent rRNA catabolic process
+is_a: GO:0016072 {is_inferred="true"} ! rRNA metabolic process
 is_a: GO:0043630 {is_inferred="true"} ! ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process
 
 [Term]
@@ -59133,8 +59221,9 @@
 [Term]
 id: GO:0098877 ! neurotransmitter receptor transport to plasma membrane
 is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
-is_a: GO:0090002 {is_inferred="true"} ! establishment of protein localization to plasma membrane
+is_a: GO:0090150 {is_inferred="true"} ! establishment of protein localization to membrane
 is_a: GO:0098876 {is_inferred="true"} ! vesicle-mediated transport to the plasma membrane
+is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
 
 [Term]
 id: GO:0098878 ! neurotransmitter receptor complex
@@ -60379,7 +60468,6 @@
 id: GO:0099638 ! endosome to plasma membrane protein transport
 is_a: GO:0015031 {is_inferred="true"} ! protein transport
 is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
-is_a: GO:0072659 {is_inferred="true"} ! protein localization to plasma membrane
 is_a: GO:0090002 {is_inferred="true"} ! establishment of protein localization to plasma membrane
 is_a: GO:1990126 {is_inferred="true"} ! retrograde transport, endosome to plasma membrane
 
@@ -77823,7 +77911,6 @@
 [Term]
 id: GO:1903445 ! protein transport from ciliary membrane to plasma membrane
 is_a: GO:0032594 {is_inferred="true"} ! protein transport within lipid bilayer
-is_a: GO:0098876 {is_inferred="true"} ! vesicle-mediated transport to the plasma membrane
 
 [Term]
 id: GO:1903446 ! geraniol metabolic process
@@ -78253,7 +78340,7 @@
 
 [Term]
 id: GO:1903540 ! establishment of protein localization to postsynaptic membrane
-is_a: GO:0090002 {is_inferred="true"} ! establishment of protein localization to plasma membrane
+is_a: GO:0090150 {is_inferred="true"} ! establishment of protein localization to membrane
 is_a: GO:1903539 {is_inferred="true"} ! protein localization to postsynaptic membrane
 
 [Term]
@@ -88244,16 +88331,16 @@
 
 [Term]
 id: GO:1905610 ! regulation of mRNA cap binding
-is_a: GO:1905214 {is_inferred="true"} ! regulation of RNA binding
+is_a: GO:1902415 {is_inferred="true"} ! regulation of mRNA binding
 
 [Term]
 id: GO:1905611 ! negative regulation of mRNA cap binding
-is_a: GO:1905215 {is_inferred="true"} ! negative regulation of RNA binding
+is_a: GO:1904572 {is_inferred="true"} ! negative regulation of mRNA binding
 is_a: GO:1905610 {is_inferred="true"} ! regulation of mRNA cap binding
 
 [Term]
 id: GO:1905612 ! positive regulation of mRNA cap binding
-is_a: GO:1905216 {is_inferred="true"} ! positive regulation of RNA binding
+is_a: GO:1902416 {is_inferred="true"} ! positive regulation of mRNA binding
 is_a: GO:1905610 {is_inferred="true"} ! regulation of mRNA cap binding
 
 [Term]
------------------------------------------------------------------------
r38126 | davidos | 2017-01-18 02:30:19 -0800 (Wed, 18 Jan 2017) | 1 line

Fixed non ascii char (was typo anyway).

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38129)
+++ go_inferences.obo	(working copy)
@@ -30496,7 +30496,9 @@
 
 [Term]
 id: GO:0039699 ! viral mRNA cap methylation
+is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
 is_a: GO:0044033 {is_inferred="true"} ! multi-organism metabolic process
+is_a: GO:1901698 {is_inferred="true"} ! response to nitrogen compound
 
 [Term]
 id: GO:0040001 ! establishment of mitotic spindle localization
@@ -69079,6 +69081,11 @@
 is_a: GO:0022857 {is_inferred="true"} ! transmembrane transporter activity
 
 [Term]
+id: GO:1901619 ! tRNA methylation in response to nitrogen starvation
+is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
+is_a: GO:1901698 {is_inferred="true"} ! response to nitrogen compound
+
+[Term]
 id: GO:1901620 ! regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
 is_a: GO:0008589 {is_inferred="true"} ! regulation of smoothened signaling pathway
 is_a: GO:0045995 {is_inferred="true"} ! regulation of embryonic development
@@ -96780,7 +96787,6 @@
 
 [Term]
 id: PR:000000001 ! protein
-is_a: BFO:0000004 {is_inferred="true"}
 is_a: CHEBI:33695 {is_inferred="true"} ! information biomacromolecule
 
 [Term]
------------------------------------------------------------------------
r38126 | davidos | 2017-01-18 02:30:19 -0800 (Wed, 18 Jan 2017) | 1 line

Fixed non ascii char (was typo anyway).

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38126)
+++ go_inferences.obo	(working copy)
@@ -2,6 +2,14 @@
 ontology: go/extensions/go_inferences
 
 [Term]
+id: CHEBI:13534 ! acyl-carrier protein
+is_a: PR:000000001 {is_inferred="true"} ! protein
+
+[Term]
+id: CHEBI:15358 ! histone
+is_a: PR:000000001 {is_inferred="true"} ! protein
+
+[Term]
 id: CHEBI:15377 ! water
 is_a: GOCHE:37527 {is_inferred="true"} ! substance with acid chemical property
 
@@ -58,10 +66,22 @@
 is_a: GOCHE:37527 {is_inferred="true"} ! substance with acid chemical property
 
 [Term]
+id: CHEBI:33837 ! conjugated protein
+is_a: PR:000000001 {is_inferred="true"} ! protein
+
+[Term]
+id: CHEBI:36080 ! protein
+is_a: PR:000018263 {is_inferred="true"} ! amino acid chain
+
+[Term]
 id: CHEBI:38150 ! enterobactin(6-)
 is_a: GOCHE:24028 {is_inferred="true"} ! substance with iron(3+) chelator role
 
 [Term]
+id: CHEBI:38560 ! simple protein
+is_a: PR:000000001 {is_inferred="true"} ! protein
+
+[Term]
 id: CHEBI:41189 ! butane-1,4-diol
 is_a: GOCHE:37527 {is_inferred="true"} ! substance with acid chemical property
 
@@ -159,7 +179,6 @@
 [Term]
 id: GO:0000042 ! protein targeting to Golgi
 is_a: GO:0006605 {is_inferred="true"} ! protein targeting
-is_a: GO:0034067 {is_inferred="true"} ! protein localization to Golgi apparatus
 
 [Term]
 id: GO:0000045 ! autophagosome assembly
@@ -6524,6 +6543,7 @@
 [Term]
 id: GO:0006516 ! glycoprotein catabolic process
 is_a: GO:0009100 {is_inferred="true"} ! glycoprotein metabolic process
+is_a: GO:0030163 {is_inferred="true"} ! protein catabolic process
 is_a: GO:1901136 {is_inferred="true"} ! carbohydrate derivative catabolic process
 
 [Term]
@@ -6883,7 +6903,6 @@
 [Term]
 id: GO:0006612 ! protein targeting to membrane
 is_a: GO:0006605 {is_inferred="true"} ! protein targeting
-is_a: GO:0072657 {is_inferred="true"} ! protein localization to membrane
 is_a: GO:0090150 {is_inferred="true"} ! establishment of protein localization to membrane
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
@@ -6896,7 +6915,6 @@
 [Term]
 id: GO:0006623 ! protein targeting to vacuole
 is_a: GO:0006605 {is_inferred="true"} ! protein targeting
-is_a: GO:0072665 {is_inferred="true"} ! protein localization to vacuole
 
 [Term]
 id: GO:0006624 ! vacuolar protein processing
@@ -6906,13 +6924,11 @@
 id: GO:0006625 ! protein targeting to peroxisome
 is_a: GO:0006605 {is_inferred="true"} ! protein targeting
 is_a: GO:0043574 {is_inferred="true"} ! peroxisomal transport
-is_a: GO:0072662 {is_inferred="true"} ! protein localization to peroxisome
 
 [Term]
 id: GO:0006626 ! protein targeting to mitochondrion
 is_a: GO:0006605 {is_inferred="true"} ! protein targeting
 is_a: GO:0006839 {is_inferred="true"} ! mitochondrial transport
-is_a: GO:0070585 {is_inferred="true"} ! protein localization to mitochondrion
 
 [Term]
 id: GO:0006631 ! fatty acid metabolic process
@@ -8933,6 +8949,7 @@
 
 [Term]
 id: GO:0009100 ! glycoprotein metabolic process
+is_a: GO:0019538 {is_inferred="true"} ! protein metabolic process
 is_a: GO:1901135 {is_inferred="true"} ! carbohydrate derivative metabolic process
 
 [Term]
@@ -16013,6 +16030,7 @@
 
 [Term]
 id: GO:0016063 ! rhodopsin biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 is_a: GO:0044711 {is_inferred="true"} ! single-organism biosynthetic process
 
 [Term]
@@ -19208,9 +19226,12 @@
 is_a: GO:0044422 {is_inferred="true"} ! organelle part
 
 [Term]
+id: GO:0020027 ! hemoglobin metabolic process
+is_a: GO:0019538 {is_inferred="true"} ! protein metabolic process
+
+[Term]
 id: GO:0020028 ! hemoglobin import
-is_a: GO:0045184 {is_inferred="true"} ! establishment of protein localization
-is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
+is_a: GO:0017038 {is_inferred="true"} ! protein import
 
 [Term]
 id: GO:0020037 ! heme binding
@@ -19787,7 +19808,6 @@
 
 [Term]
 id: GO:0030150 ! protein import into mitochondrial matrix
-is_a: GO:0070585 {is_inferred="true"} ! protein localization to mitochondrion
 is_a: GO:0072655 {is_inferred="true"} ! establishment of protein localization to mitochondrion
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
@@ -20181,7 +20201,7 @@
 
 [Term]
 id: GO:0030492 ! hemoglobin binding
-is_a: GO:0005488 {is_inferred="true"} ! binding
+is_a: GO:0005515 {is_inferred="true"} ! protein binding
 
 [Term]
 id: GO:0030493 ! bacteriochlorophyll metabolic process
@@ -27339,6 +27359,10 @@
 is_a: GO:0045840 {is_inferred="true"} ! positive regulation of mitotic nuclear division
 
 [Term]
+id: GO:0034189 ! very-low-density lipoprotein particle binding
+is_a: GO:0005515 {is_inferred="true"} ! protein binding
+
+[Term]
 id: GO:0034192 ! D-galactonate metabolic process
 is_a: GO:0019583 {is_inferred="true"} ! galactonate metabolic process
 
@@ -27792,11 +27816,12 @@
 
 [Term]
 id: GO:0034436 ! glycoprotein transport
-is_a: GO:0045184 {is_inferred="true"} ! establishment of protein localization
+is_a: GO:0015031 {is_inferred="true"} ! protein transport
 is_a: GO:1901264 {is_inferred="true"} ! carbohydrate derivative transport
 
 [Term]
 id: GO:0034437 ! glycoprotein transporter activity
+is_a: GO:0008565 {is_inferred="true"} ! protein transporter activity
 is_a: GO:1901505 {is_inferred="true"} ! carbohydrate derivative transporter activity
 
 [Term]
@@ -29107,6 +29132,7 @@
 
 [Term]
 id: GO:0035592 ! establishment of protein localization to extracellular region
+is_a: GO:0071692 {is_inferred="true"} ! protein localization to extracellular region
 is_a: GO:1902578 {is_inferred="true"} ! single-organism localization
 
 [Term]
@@ -30600,15 +30626,15 @@
 
 [Term]
 id: GO:0042091 ! interleukin-10 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042094 ! interleukin-2 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042097 ! interleukin-4 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042101 ! T cell receptor complex
@@ -30639,7 +30665,7 @@
 
 [Term]
 id: GO:0042109 ! lymphotoxin A biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042119 ! neutrophil activation
@@ -30691,7 +30717,7 @@
 
 [Term]
 id: GO:0042157 ! lipoprotein metabolic process
-is_a: GO:0043170 {is_inferred="true"} ! macromolecule metabolic process
+is_a: GO:0019538 {is_inferred="true"} ! protein metabolic process
 
 [Term]
 id: GO:0042158 ! lipoprotein biosynthetic process
@@ -30699,7 +30725,7 @@
 
 [Term]
 id: GO:0042159 ! lipoprotein catabolic process
-is_a: GO:0009057 {is_inferred="true"} ! macromolecule catabolic process
+is_a: GO:0030163 {is_inferred="true"} ! protein catabolic process
 is_a: GO:0042157 {is_inferred="true"} ! lipoprotein metabolic process
 
 [Term]
@@ -30950,71 +30976,71 @@
 
 [Term]
 id: GO:0042222 ! interleukin-1 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042223 ! interleukin-3 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042225 ! interleukin-5 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042226 ! interleukin-6 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042227 ! interleukin-7 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042228 ! interleukin-8 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042229 ! interleukin-9 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042230 ! interleukin-11 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042231 ! interleukin-13 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042233 ! interleukin-15 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042234 ! interleukin-16 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042235 ! interleukin-17 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042236 ! interleukin-19 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042237 ! interleukin-20 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042238 ! interleukin-21 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042239 ! interleukin-22 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042241 ! interleukin-18 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042243 ! asexual spore wall assembly
@@ -31026,7 +31052,7 @@
 
 [Term]
 id: GO:0042253 ! granulocyte macrophage colony-stimulating factor biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0042255 ! ribosome assembly
@@ -31720,6 +31746,7 @@
 [Term]
 id: GO:0042540 ! hemoglobin catabolic process
 is_a: GO:0020027 {is_inferred="true"} ! hemoglobin metabolic process
+is_a: GO:0030163 {is_inferred="true"} ! protein catabolic process
 
 [Term]
 id: GO:0042541 ! hemoglobin biosynthetic process
@@ -32626,13 +32653,12 @@
 
 [Term]
 id: GO:0042953 ! lipoprotein transport
+is_a: GO:0015031 {is_inferred="true"} ! protein transport
 is_a: GO:0044872 {is_inferred="true"} ! lipoprotein localization
-is_a: GO:0045184 {is_inferred="true"} ! establishment of protein localization
-is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 
 [Term]
 id: GO:0042954 ! lipoprotein transporter activity
-is_a: GO:0005215 {is_inferred="true"} ! transporter activity
+is_a: GO:0008565 {is_inferred="true"} ! protein transporter activity
 
 [Term]
 id: GO:0042955 ! dextrin transport
@@ -32651,6 +32677,18 @@
 is_a: GO:0015159 {is_inferred="true"} ! polysaccharide transmembrane transporter activity
 
 [Term]
+id: GO:0042964 ! thioredoxin biosynthetic process
+is_a: GO:0019538 {is_inferred="true"} ! protein metabolic process
+
+[Term]
+id: GO:0042965 ! glutaredoxin biosynthetic process
+is_a: GO:0019538 {is_inferred="true"} ! protein metabolic process
+
+[Term]
+id: GO:0042967 ! acyl-carrier-protein biosynthetic process
+is_a: GO:0019538 {is_inferred="true"} ! protein metabolic process
+
+[Term]
 id: GO:0042968 ! homoserine transport
 is_a: GO:0015807 {is_inferred="true"} ! L-amino acid transport
 
@@ -32668,21 +32706,15 @@
 
 [Term]
 id: GO:0042983 ! amyloid precursor protein biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
-id: GO:0042984 ! regulation of amyloid precursor protein biosynthetic process
-is_a: GO:0051246 {is_inferred="true"} ! regulation of protein metabolic process
-
-[Term]
 id: GO:0042985 ! negative regulation of amyloid precursor protein biosynthetic process
 is_a: GO:0042984 {is_inferred="true"} ! regulation of amyloid precursor protein biosynthetic process
-is_a: GO:0051248 {is_inferred="true"} ! negative regulation of protein metabolic process
 
 [Term]
 id: GO:0042986 ! positive regulation of amyloid precursor protein biosynthetic process
 is_a: GO:0042984 {is_inferred="true"} ! regulation of amyloid precursor protein biosynthetic process
-is_a: GO:0051247 {is_inferred="true"} ! positive regulation of protein metabolic process
 
 [Term]
 id: GO:0042990 ! regulation of transcription factor import into nucleus
@@ -34945,6 +34977,7 @@
 
 [Term]
 id: GO:0044859 ! protein insertion into plasma membrane raft
+is_a: GO:0044860 {is_inferred="true"} ! protein localization to plasma membrane raft
 is_a: GO:0071210 {is_inferred="true"} ! protein insertion into membrane raft
 is_a: GO:0098737 {is_inferred="true"} ! protein insertion into plasma membrane
 
@@ -34960,11 +34993,9 @@
 
 [Term]
 id: GO:0044862 ! protein transport out of plasma membrane raft
-is_a: GO:0072657 {is_inferred="true"} ! protein localization to membrane
 is_a: GO:0090002 {is_inferred="true"} ! establishment of protein localization to plasma membrane
 is_a: GO:0098876 {is_inferred="true"} ! vesicle-mediated transport to the plasma membrane
 is_a: GO:0099632 {is_inferred="true"} ! protein transport within plasma membrane
-is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
 
 [Term]
 id: GO:0044866 ! modulation by host of viral exo-alpha-sialidase activity
@@ -34983,6 +35014,14 @@
 is_a: GO:1903019 {is_inferred="true"} ! negative regulation of glycoprotein metabolic process
 
 [Term]
+id: GO:0044872 ! lipoprotein localization
+is_a: GO:0008104 {is_inferred="true"} ! protein localization
+
+[Term]
+id: GO:0044873 ! lipoprotein localization to membrane
+is_a: GO:0072657 {is_inferred="true"} ! protein localization to membrane
+
+[Term]
 id: GO:0044874 ! lipoprotein localization to outer membrane
 is_a: GO:0044873 {is_inferred="true"} ! lipoprotein localization to membrane
 
@@ -35010,25 +35049,19 @@
 [Term]
 id: GO:0045036 ! protein targeting to chloroplast
 is_a: GO:0006605 {is_inferred="true"} ! protein targeting
-is_a: GO:0072598 {is_inferred="true"} ! protein localization to chloroplast
 
 [Term]
 id: GO:0045039 ! protein import into mitochondrial inner membrane
-is_a: GO:0070585 {is_inferred="true"} ! protein localization to mitochondrion
-is_a: GO:0072657 {is_inferred="true"} ! protein localization to membrane
 is_a: GO:0090151 {is_inferred="true"} ! establishment of protein localization to mitochondrial membrane
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:0045040 ! protein import into mitochondrial outer membrane
-is_a: GO:0070585 {is_inferred="true"} ! protein localization to mitochondrion
-is_a: GO:0072657 {is_inferred="true"} ! protein localization to membrane
 is_a: GO:0090151 {is_inferred="true"} ! establishment of protein localization to mitochondrial membrane
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:0045041 ! protein import into mitochondrial intermembrane space
-is_a: GO:0070585 {is_inferred="true"} ! protein localization to mitochondrion
 is_a: GO:0072655 {is_inferred="true"} ! establishment of protein localization to mitochondrion
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
@@ -35040,7 +35073,6 @@
 [Term]
 id: GO:0045047 ! protein targeting to ER
 is_a: GO:0006605 {is_inferred="true"} ! protein targeting
-is_a: GO:0070972 {is_inferred="true"} ! protein localization to endoplasmic reticulum
 
 [Term]
 id: GO:0045069 ! regulation of viral genome replication
@@ -35248,6 +35280,10 @@
 is_a: GO:0007267 {is_inferred="true"} ! cell-cell signaling
 
 [Term]
+id: GO:0045184 ! establishment of protein localization
+is_a: GO:0008104 {is_inferred="true"} ! protein localization
+
+[Term]
 id: GO:0045186 ! zonula adherens assembly
 is_a: GO:0007043 {is_inferred="true"} ! cell-cell junction assembly
 is_a: GO:0034333 {is_inferred="true"} ! adherens junction assembly
@@ -35254,7 +35290,7 @@
 
 [Term]
 id: GO:0045189 ! connective tissue growth factor biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0045190 ! isotype switching
@@ -35291,25 +35327,18 @@
 is_a: GO:0045219 {is_inferred="true"} ! regulation of FasL biosynthetic process
 
 [Term]
-id: GO:0045222 ! CD4 biosynthetic process
-is_a: GO:0019538 {is_inferred="true"} ! protein metabolic process
-
-[Term]
 id: GO:0045223 ! regulation of CD4 biosynthetic process
 is_a: GO:0010559 {is_inferred="true"} ! regulation of glycoprotein biosynthetic process
-is_a: GO:0051246 {is_inferred="true"} ! regulation of protein metabolic process
 
 [Term]
 id: GO:0045224 ! positive regulation of CD4 biosynthetic process
 is_a: GO:0010560 {is_inferred="true"} ! positive regulation of glycoprotein biosynthetic process
 is_a: GO:0045223 {is_inferred="true"} ! regulation of CD4 biosynthetic process
-is_a: GO:0051247 {is_inferred="true"} ! positive regulation of protein metabolic process
 
 [Term]
 id: GO:0045225 ! negative regulation of CD4 biosynthetic process
 is_a: GO:0010561 {is_inferred="true"} ! negative regulation of glycoprotein biosynthetic process
 is_a: GO:0045223 {is_inferred="true"} ! regulation of CD4 biosynthetic process
-is_a: GO:0051248 {is_inferred="true"} ! negative regulation of protein metabolic process
 
 [Term]
 id: GO:0045229 ! external encapsulating structure organization
@@ -35572,7 +35601,7 @@
 
 [Term]
 id: GO:0045350 ! interferon-beta biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0045354 ! regulation of interferon-alpha biosynthetic process
@@ -36108,7 +36137,7 @@
 
 [Term]
 id: GO:0045524 ! interleukin-24 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0045525 ! interleukin-25 biosynthetic process
@@ -36116,7 +36145,7 @@
 
 [Term]
 id: GO:0045526 ! interleukin-26 biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0045528 ! regulation of interleukin-24 biosynthetic process
@@ -40795,6 +40824,7 @@
 
 [Term]
 id: GO:0046984 ! regulation of hemoglobin biosynthetic process
+is_a: GO:0051246 {is_inferred="true"} ! regulation of protein metabolic process
 is_a: GO:2000112 {is_inferred="true"} ! regulation of cellular macromolecule biosynthetic process
 
 [Term]
@@ -40802,10 +40832,12 @@
 is_a: GO:0010557 {is_inferred="true"} ! positive regulation of macromolecule biosynthetic process
 is_a: GO:0031328 {is_inferred="true"} ! positive regulation of cellular biosynthetic process
 is_a: GO:0046984 {is_inferred="true"} ! regulation of hemoglobin biosynthetic process
+is_a: GO:0051247 {is_inferred="true"} ! positive regulation of protein metabolic process
 
 [Term]
 id: GO:0046986 ! negative regulation of hemoglobin biosynthetic process
 is_a: GO:0046984 {is_inferred="true"} ! regulation of hemoglobin biosynthetic process
+is_a: GO:0051248 {is_inferred="true"} ! negative regulation of protein metabolic process
 is_a: GO:2000113 {is_inferred="true"} ! negative regulation of cellular macromolecule biosynthetic process
 
 [Term]
@@ -41073,7 +41105,7 @@
 
 [Term]
 id: GO:0048175 ! hepatocyte growth factor biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0048176 ! regulation of hepatocyte growth factor biosynthetic process
@@ -42462,21 +42494,21 @@
 
 [Term]
 id: GO:0050746 ! regulation of lipoprotein metabolic process
-is_a: GO:0060255 {is_inferred="true"} ! regulation of macromolecule metabolic process
+is_a: GO:0051246 {is_inferred="true"} ! regulation of protein metabolic process
 
 [Term]
 id: GO:0050747 ! positive regulation of lipoprotein metabolic process
-is_a: GO:0010604 {is_inferred="true"} ! positive regulation of macromolecule metabolic process
 is_a: GO:0050746 {is_inferred="true"} ! regulation of lipoprotein metabolic process
+is_a: GO:0051247 {is_inferred="true"} ! positive regulation of protein metabolic process
 
 [Term]
 id: GO:0050748 ! negative regulation of lipoprotein metabolic process
-is_a: GO:0010605 {is_inferred="true"} ! negative regulation of macromolecule metabolic process
 is_a: GO:0050746 {is_inferred="true"} ! regulation of lipoprotein metabolic process
+is_a: GO:0051248 {is_inferred="true"} ! negative regulation of protein metabolic process
 
 [Term]
 id: GO:0050751 ! fractalkine biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 
 [Term]
 id: GO:0050752 ! regulation of fractalkine biosynthetic process
@@ -43464,7 +43496,6 @@
 [Term]
 id: GO:0051204 ! protein insertion into mitochondrial membrane
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
-is_a: GO:1902578 {is_inferred="true"} ! single-organism localization
 
 [Term]
 id: GO:0051206 ! silicate metabolic process
@@ -46320,11 +46351,13 @@
 [Term]
 id: GO:0060310 ! regulation of elastin catabolic process
 is_a: GO:0031329 {is_inferred="true"} ! regulation of cellular catabolic process
+is_a: GO:0042176 {is_inferred="true"} ! regulation of protein catabolic process
 is_a: GO:1903018 {is_inferred="true"} ! regulation of glycoprotein metabolic process
 
 [Term]
 id: GO:0060311 ! negative regulation of elastin catabolic process
 is_a: GO:0031330 {is_inferred="true"} ! negative regulation of cellular catabolic process
+is_a: GO:0042177 {is_inferred="true"} ! negative regulation of protein catabolic process
 is_a: GO:0060310 {is_inferred="true"} ! regulation of elastin catabolic process
 is_a: GO:1903019 {is_inferred="true"} ! negative regulation of glycoprotein metabolic process
 
@@ -49516,6 +49549,14 @@
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
+id: GO:0070199 ! establishment of protein localization to chromosome
+is_a: GO:0034502 {is_inferred="true"} ! protein localization to chromosome
+
+[Term]
+id: GO:0070200 ! establishment of protein localization to telomere
+is_a: GO:0070198 {is_inferred="true"} ! protein localization to chromosome, telomeric region
+
+[Term]
 id: GO:0070202 ! regulation of establishment of protein localization to chromosome
 is_a: GO:0070201 {is_inferred="true"} ! regulation of establishment of protein localization
 is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
@@ -51473,6 +51514,10 @@
 is_a: GO:0051170 {is_inferred="true"} ! nuclear import
 
 [Term]
+id: GO:0071169 ! establishment of protein localization to chromatin
+is_a: GO:0071168 {is_inferred="true"} ! protein localization to chromatin
+
+[Term]
 id: GO:0071183 ! protocadherin-alpha-protocadherin-gamma complex
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
@@ -51481,6 +51526,14 @@
 is_a: GO:0099612 {is_inferred="true"} ! protein localization to axon
 
 [Term]
+id: GO:0071206 ! establishment of protein localization to juxtaparanode region of axon
+is_a: GO:0071205 {is_inferred="true"} ! protein localization to juxtaparanode region of axon
+
+[Term]
+id: GO:0071210 ! protein insertion into membrane raft
+is_a: GO:1903044 {is_inferred="true"} ! protein localization to membrane raft
+
+[Term]
 id: GO:0071211 ! protein targeting to vacuole involved in autophagy
 is_a: GO:0006623 {is_inferred="true"} ! protein targeting to vacuole
 
@@ -52803,10 +52856,6 @@
 is_a: GO:0008104 {is_inferred="true"} ! protein localization
 
 [Term]
-id: GO:0071693 ! protein transport within extracellular region
-is_a: GO:0071692 {is_inferred="true"} ! protein localization to extracellular region
-
-[Term]
 id: GO:0071701 ! regulation of MAPK export from nucleus
 is_a: GO:0046825 {is_inferred="true"} ! regulation of protein export from nucleus
 
@@ -54294,6 +54343,14 @@
 is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
 
 [Term]
+id: GO:0072594 ! establishment of protein localization to organelle
+is_a: GO:0033365 {is_inferred="true"} ! protein localization to organelle
+
+[Term]
+id: GO:0072596 ! establishment of protein localization to chloroplast
+is_a: GO:0072598 {is_inferred="true"} ! protein localization to chloroplast
+
+[Term]
 id: GO:0072597 ! maintenance of protein location in chloroplast
 is_a: GO:0051220 {is_inferred="true"} ! cytoplasmic sequestering of protein
 
@@ -54302,6 +54359,18 @@
 is_a: GO:0033365 {is_inferred="true"} ! protein localization to organelle
 
 [Term]
+id: GO:0072599 ! establishment of protein localization to endoplasmic reticulum
+is_a: GO:0070972 {is_inferred="true"} ! protein localization to endoplasmic reticulum
+
+[Term]
+id: GO:0072600 ! establishment of protein localization to Golgi
+is_a: GO:0034067 {is_inferred="true"} ! protein localization to Golgi apparatus
+
+[Term]
+id: GO:0072655 ! establishment of protein localization to mitochondrion
+is_a: GO:0070585 {is_inferred="true"} ! protein localization to mitochondrion
+
+[Term]
 id: GO:0072656 ! maintenance of protein location in mitochondrion
 is_a: GO:0051220 {is_inferred="true"} ! cytoplasmic sequestering of protein
 
@@ -54317,7 +54386,6 @@
 [Term]
 id: GO:0072661 ! protein targeting to plasma membrane
 is_a: GO:0098876 {is_inferred="true"} ! vesicle-mediated transport to the plasma membrane
-is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
 
 [Term]
 id: GO:0072662 ! protein localization to peroxisome
@@ -54324,6 +54392,10 @@
 is_a: GO:0033365 {is_inferred="true"} ! protein localization to organelle
 
 [Term]
+id: GO:0072663 ! establishment of protein localization to peroxisome
+is_a: GO:0072662 {is_inferred="true"} ! protein localization to peroxisome
+
+[Term]
 id: GO:0072664 ! maintenance of protein location in peroxisome
 is_a: GO:0051220 {is_inferred="true"} ! cytoplasmic sequestering of protein
 
@@ -54332,6 +54404,10 @@
 is_a: GO:0033365 {is_inferred="true"} ! protein localization to organelle
 
 [Term]
+id: GO:0072666 ! establishment of protein localization to vacuole
+is_a: GO:0072665 {is_inferred="true"} ! protein localization to vacuole
+
+[Term]
 id: GO:0072667 ! maintenance of protein location in vacuole
 is_a: GO:0051220 {is_inferred="true"} ! cytoplasmic sequestering of protein
 
@@ -54358,7 +54434,6 @@
 
 [Term]
 id: GO:0072693 ! protein targeting to prospore membrane
-is_a: GO:1902657 {is_inferred="true"} ! protein localization to prospore membrane
 is_a: GO:1902658 {is_inferred="true"} ! establishment of protein localization to prospore membrane
 
 [Term]
@@ -55823,6 +55898,10 @@
 is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
+id: GO:0090002 ! establishment of protein localization to plasma membrane
+is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
+
+[Term]
 id: GO:0090003 ! regulation of establishment of protein localization to plasma membrane
 is_a: GO:0070201 {is_inferred="true"} ! regulation of establishment of protein localization
 is_a: GO:1903076 {is_inferred="true"} ! regulation of protein localization to plasma membrane
@@ -56260,10 +56339,13 @@
 is_a: GO:0090148 {is_inferred="true"} ! membrane fission
 
 [Term]
+id: GO:0090150 ! establishment of protein localization to membrane
+is_a: GO:0072657 {is_inferred="true"} ! protein localization to membrane
+
+[Term]
 id: GO:0090151 ! establishment of protein localization to mitochondrial membrane
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
 is_a: GO:0072655 {is_inferred="true"} ! establishment of protein localization to mitochondrion
-is_a: GO:1902578 {is_inferred="true"} ! single-organism localization
 
 [Term]
 id: GO:0090152 ! establishment of protein localization to mitochondrial membrane involved in mitochondrial fission
@@ -58590,6 +58672,16 @@
 is_a: GO:0071435 {is_inferred="true"} ! potassium ion export
 
 [Term]
+id: GO:0098674 ! extrinsic component of neuronal dense core vesicle membrane
+is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0098922 {is_inferred="true"} ! extrinsic component of dense core granule membrane
+
+[Term]
+id: GO:0098675 ! intrinsic component of neuronal dense core vesicle membrane
+is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0098956 {is_inferred="true"} ! intrinsic component of dense core granule membrane
+
+[Term]
 id: GO:0098700 ! neurotransmitter loading into synaptic vesicle
 is_a: GO:0006836 {is_inferred="true"} ! neurotransmitter transport
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
@@ -59039,10 +59131,8 @@
 [Term]
 id: GO:0098877 ! neurotransmitter receptor transport to plasma membrane
 is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
-is_a: GO:0072657 {is_inferred="true"} ! protein localization to membrane
 is_a: GO:0090002 {is_inferred="true"} ! establishment of protein localization to plasma membrane
 is_a: GO:0098876 {is_inferred="true"} ! vesicle-mediated transport to the plasma membrane
-is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
 
 [Term]
 id: GO:0098878 ! neurotransmitter receptor complex
@@ -59433,7 +59523,6 @@
 [Term]
 id: GO:0098969 ! neurotransmitter receptor transport to postsynaptic membrane
 is_a: GO:0098877 {is_inferred="true"} ! neurotransmitter receptor transport to plasma membrane
-is_a: GO:1903539 {is_inferred="true"} ! protein localization to postsynaptic membrane
 is_a: GO:1903540 {is_inferred="true"} ! establishment of protein localization to postsynaptic membrane
 
 [Term]
@@ -59632,8 +59721,7 @@
 [Term]
 id: GO:0099036 ! anchored component of neuronal dense core vesicle membrane
 is_a: GO:0031225 {is_inferred="true"} ! anchored component of membrane
-is_a: GO:0097458 {is_inferred="true"} ! neuron part
-is_a: GO:0098956 {is_inferred="true"} ! intrinsic component of dense core granule membrane
+is_a: GO:0098675 {is_inferred="true"} ! intrinsic component of neuronal dense core vesicle membrane
 
 [Term]
 id: GO:0099037 ! anchored component of presynaptic endosome membrane
@@ -59736,8 +59824,7 @@
 [Term]
 id: GO:0099066 ! integral component of neuronal dense core vesicle membrane
 is_a: GO:0031301 {is_inferred="true"} ! integral component of organelle membrane
-is_a: GO:0097458 {is_inferred="true"} ! neuron part
-is_a: GO:0098956 {is_inferred="true"} ! intrinsic component of dense core granule membrane
+is_a: GO:0098675 {is_inferred="true"} ! intrinsic component of neuronal dense core vesicle membrane
 
 [Term]
 id: GO:0099067 ! integral component of presynaptic endosome membrane
@@ -59894,9 +59981,7 @@
 
 [Term]
 id: GO:0099110 ! microtubule polymerization based protein transport to cell tip cortex
-is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0099112 {is_inferred="true"} ! microtubule polymerization based protein transport
-is_a: GO:0099118 {is_inferred="true"} ! microtubule-based protein transport
 is_a: GO:1990896 {is_inferred="true"} ! protein localization to cell cortex of cell tip
 
 [Term]
@@ -59906,10 +59991,9 @@
 
 [Term]
 id: GO:0099112 ! microtubule polymerization based protein transport
-is_a: GO:0045184 {is_inferred="true"} ! establishment of protein localization
-is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
+is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0099098 {is_inferred="true"} ! microtubule polymerization based movement
-is_a: GO:0099111 {is_inferred="true"} ! microtubule-based transport
+is_a: GO:0099118 {is_inferred="true"} ! microtubule-based protein transport
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
@@ -73114,12 +73198,12 @@
 
 [Term]
 id: GO:1902440 ! protein localization to mitotic spindle pole body
-is_a: GO:1905508 {is_inferred="true"} ! protein localization to microtubule organizing center
+is_a: GO:0071988 {is_inferred="true"} ! protein localization to spindle pole body
 
 [Term]
 id: GO:1902441 ! protein localization to meiotic spindle pole body
 is_a: GO:0022414 {is_inferred="true"} ! reproductive process
-is_a: GO:1905508 {is_inferred="true"} ! protein localization to microtubule organizing center
+is_a: GO:0071988 {is_inferred="true"} ! protein localization to spindle pole body
 
 [Term]
 id: GO:1902442 ! regulation of ripoptosome assembly involved in necroptotic process
@@ -73542,12 +73626,12 @@
 
 [Term]
 id: GO:1902542 ! regulation of protein localization to mitotic spindle pole body
-is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
+is_a: GO:1902363 {is_inferred="true"} ! regulation of protein localization to spindle pole body
 
 [Term]
 id: GO:1902543 ! negative regulation of protein localization to mitotic spindle pole body
+is_a: GO:1902364 {is_inferred="true"} ! negative regulation of protein localization to spindle pole body
 is_a: GO:1902542 {is_inferred="true"} ! regulation of protein localization to mitotic spindle pole body
-is_a: GO:1903828 {is_inferred="true"} ! negative regulation of cellular protein localization
 
 [Term]
 id: GO:1902544 ! regulation of DNA N-glycosylase activity
@@ -74094,6 +74178,7 @@
 [Term]
 id: GO:1902658 ! establishment of protein localization to prospore membrane
 is_a: GO:0090150 {is_inferred="true"} ! establishment of protein localization to membrane
+is_a: GO:1902657 {is_inferred="true"} ! protein localization to prospore membrane
 
 [Term]
 id: GO:1902659 ! regulation of glucose mediated signaling pathway
@@ -75796,18 +75881,18 @@
 [Term]
 id: GO:1903018 ! regulation of glycoprotein metabolic process
 is_a: GO:0031323 {is_inferred="true"} ! regulation of cellular metabolic process
-is_a: GO:0060255 {is_inferred="true"} ! regulation of macromolecule metabolic process
+is_a: GO:0051246 {is_inferred="true"} ! regulation of protein metabolic process
 
 [Term]
 id: GO:1903019 ! negative regulation of glycoprotein metabolic process
-is_a: GO:0010605 {is_inferred="true"} ! negative regulation of macromolecule metabolic process
 is_a: GO:0031324 {is_inferred="true"} ! negative regulation of cellular metabolic process
+is_a: GO:0051248 {is_inferred="true"} ! negative regulation of protein metabolic process
 is_a: GO:1903018 {is_inferred="true"} ! regulation of glycoprotein metabolic process
 
 [Term]
 id: GO:1903020 ! positive regulation of glycoprotein metabolic process
-is_a: GO:0010604 {is_inferred="true"} ! positive regulation of macromolecule metabolic process
 is_a: GO:0031325 {is_inferred="true"} ! positive regulation of cellular metabolic process
+is_a: GO:0051247 {is_inferred="true"} ! positive regulation of protein metabolic process
 is_a: GO:1903018 {is_inferred="true"} ! regulation of glycoprotein metabolic process
 
 [Term]
@@ -77731,9 +77816,7 @@
 [Term]
 id: GO:1903445 ! protein transport from ciliary membrane to plasma membrane
 is_a: GO:0032594 {is_inferred="true"} ! protein transport within lipid bilayer
-is_a: GO:0072657 {is_inferred="true"} ! protein localization to membrane
 is_a: GO:0098876 {is_inferred="true"} ! vesicle-mediated transport to the plasma membrane
-is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
 
 [Term]
 id: GO:1903446 ! geraniol metabolic process
@@ -78164,6 +78247,7 @@
 [Term]
 id: GO:1903540 ! establishment of protein localization to postsynaptic membrane
 is_a: GO:0090002 {is_inferred="true"} ! establishment of protein localization to plasma membrane
+is_a: GO:1903539 {is_inferred="true"} ! protein localization to postsynaptic membrane
 
 [Term]
 id: GO:1903541 ! regulation of exosomal secretion
@@ -78495,7 +78579,7 @@
 
 [Term]
 id: GO:1903604 ! cytochrome metabolic process
-is_a: GO:0043170 {is_inferred="true"} ! macromolecule metabolic process
+is_a: GO:0019538 {is_inferred="true"} ! protein metabolic process
 
 [Term]
 id: GO:1903605 ! cytochrome biosynthetic process
@@ -82233,7 +82317,7 @@
 
 [Term]
 id: GO:1904391 ! response to ciliary neurotrophic factor
-is_a: GO:0042221 {is_inferred="true"} ! response to chemical
+is_a: GO:0010033 {is_inferred="true"} ! response to organic substance
 
 [Term]
 id: GO:1904392 ! cellular response to ciliary neurotrophic factor
@@ -88275,6 +88359,7 @@
 [Term]
 id: GO:1905633 ! establishment of protein localization to euchromatin
 is_a: GO:0071169 {is_inferred="true"} ! establishment of protein localization to chromatin
+is_a: GO:1905632 {is_inferred="true"} ! protein localization to euchromatin
 
 [Term]
 id: GO:1905634 ! regulation of protein localization to chromatin
@@ -96694,6 +96779,735 @@
 is_a: CHEBI:24431 {is_inferred="true"} ! chemical entity
 
 [Term]
+id: PR:000000001 ! protein
+is_a: BFO:0000004 {is_inferred="true"}
+is_a: CHEBI:33695 {is_inferred="true"} ! information biomacromolecule
+
+[Term]
+id: PR:000000008 ! TGF-beta-like cystine-knot cytokine
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000000019 ! mitogen-activated protein kinase
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000000028 ! small GTPase
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000000033 ! tumor necrosis factor, TNF-like
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001004 ! CD4 molecule
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001091 ! interleukin-1
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001092 ! interleukin-17
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001094 ! rhodopsin-like G-protein coupled receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001096 ! Toll-like receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001315 ! G-protein coupled receptor frizzled
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001317 ! interleukin-7
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001327 ! cadherin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001335 ! class 2 cytokine, IL-10 type
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001348 ! erythrocyte membrane protein Rh
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001349 ! fibroblast growth factor receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001353 ! granulocyte colony-stimulating factor receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001357 ! intercellular adhesion molecule 1/3
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001366 ! interleukin-11
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001368 ! interleukin-12 subunit alpha
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001369 ! interleukin-12 subunit beta
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001370 ! interleukin-13
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001373 ! interleukin-15
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001374 ! interleukin-16
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001376 ! interleukin-18
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001379 ! interleukin-2
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001382 ! interleukin-21
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001383 ! interleukin-22
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001387 ! interleukin-3
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001389 ! interleukin-33
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001391 ! interleukin-4
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001392 ! interleukin-5
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001393 ! interleukin-6
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+
+[Term]
+id: PR:000001395 ! interleukin-8
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+
+[Term]
+id: PR:000001396 ! interleukin-9
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+
+[Term]
+id: PR:000001397 ! interleukin-9 receptor
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+
+[Term]
+id: PR:000001753 ! transcription factor NF-kappa-B subunit
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+
+[Term]
+id: PR:000001808 ! C/C-C motif small inducible chemokine
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001810 ! CSF-1/PDGF receptor-type tyrosine-protein kinase
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001812 ! EGF receptor type tyrosine-protein kinase
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+
+[Term]
+id: PR:000001816 ! HGF/MSP receptor type tyrosine-protein kinase
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
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+id: PR:000001855 ! fractalkine
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
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+[Term]
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+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001902 ! nuclear receptor ROR-gamma
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001926 ! semaphorin
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+
+[Term]
+id: PR:000001946 ! tumor necrosis factor ligand superfamily member 10/11
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000001971 ! vascular endothelial growth factor receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
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+[Term]
+id: PR:000002198 ! catenin beta-1
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000002201 ! dynein light chain
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+
+[Term]
+id: PR:000003035 ! cellular tumor antigen p53
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
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+
+[Term]
+id: PR:000003171 ! IGFBP-related protein
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
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+id: PR:000003237 ! 14-3-3 protein
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+[Term]
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+[Term]
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+is_a: CHEBI:36080 {is_inferred="true"} ! protein
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+[Term]
+id: PR:000003777 ! adiponectin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
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+is_a: CHEBI:36080 {is_inferred="true"} ! protein
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+[Term]
+id: PR:000004126 ! serum amyloid P-component
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000004135 ! apelin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000004140 ! apolipoprotein A-I
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000004168 ! amyloid beta A4 protein
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+
+[Term]
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+
+[Term]
+id: PR:000004580 ! beta-2-microglobulin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000004972 ! calcitonin receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000004974 ! caldesmon
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000004978 ! calmodulin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000005110 ! cholecystokinin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000005663 ! ciliary neurotrophic factor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000005716 ! collagen type IV alpha-3-binding protein
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000005869 ! corticotropin-releasing factor receptor 1
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000005870 ! corticotropin-releasing factor receptor 2
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000005931 ! granulocyte-macrophage colony-stimulating factor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000005932 ! granulocyte colony-stimulating factor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000006013 ! catenin delta-2
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000006267 ! dystroglycan
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000006909 ! elongation factor 2
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000006928 ! pro-epidermal growth factor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000006990 ! eukaryotic translation initiation factor 4E
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007141 ! erythropoietin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007142 ! erythropoietin receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007204 ! estrogen receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007494 ! fibroblast growth factor 3
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007495 ! fibroblast growth factor 4
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007496 ! fibroblast growth factor 5
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007497 ! fibroblast growth factor 6
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007499 ! fibroblast growth factor 8
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007555 ! filamin-A
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007556 ! filamin-B
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007557 ! filamin-C
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007581 ! fibronectin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007636 ! forkhead box protein N1
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007806 ! galanin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007856 ! gastrin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007892 ! glucagon receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007893 ! GTP cyclohydrolase 1
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007928 ! glial cell line-derived neurotrophic factor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007970 ! growth hormone receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007971 ! somatoliberin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007972 ! growth hormone-releasing hormone receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007973 ! appetite-regulating hormone
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000007988 ! gastric inhibitory polypeptide receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000008476 ! orexin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000008534 ! hepatocyte growth factor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000008630 ! high mobility group protein B1
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000008636 ! 3-hydroxy-3-methylglutaryl-coenzyme A reductase
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000008725 ! haptoglobin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000008875 ! islet amyloid polypeptide
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000008878 ! bone sialoprotein 2
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000008888 ! isocitrate dehydrogenase [NADP], mitochondrial
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000008910 ! interferon-induced helicase C domain-containing protein 1
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000008942 ! insulin-like growth factor II
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000008998 ! interleukin-21 receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000009001 ! interleukin-23 receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000009054 ! insulin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000009064 ! insulin receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000009182 ! insulin-like growth factor I
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000009345 ! kit ligand
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000009744 ! low-density lipoprotein receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000009799 ! leukemia inhibitory factor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000009978 ! lactotransferrin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000010413 ! macrophage migration inhibitory factor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000010444 ! mitogen-activated protein kinase kinase kinase
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000010818 ! myogenic factor 5
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000010855 ! myosin-Ia
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000010877 ! myogenin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000010882 ! myozenin-1
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000011116 ! NEDD8
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000011164 ! nuclear factor of activated T-cells, cytoplasmic 2
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000011166 ! nuclear factor of activated T-cells, cytoplasmic 3
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000011167 ! nuclear factor of activated T-cells, cytoplasmic 4
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000011374 ! atrial natriuretic factor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000011387 ! neuropeptide Y
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000011406 ! glucocorticoid receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000011407 ! mineralocorticoid receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000012059 ! oncostatin-M
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000012421 ! proliferating cell nuclear antigen
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000012621 ! progesterone receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000012705 ! polymeric immunoglobulin receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000012826 ! urokinase-type plasminogen activator
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000013164 ! pancreatic prohormone
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000013246 ! prolactin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000013248 ! prolactin receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000013429 ! parathyroid hormone
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000013526 ! peptide YY
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000013743 ! ras GTPase-activating protein 1
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000014543 ! secretin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000014544 ! secretin receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000014717 ! protein SET
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000014841 ! sonic hedgehog protein
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000015288 ! smoothened
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000015557 ! spondin-1
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000015794 ! syntaxin-2
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000015795 ! syntaxin-3
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000015797 ! syntaxin-5
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000015798 ! syntaxin-6
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000015975 ! sperm motility kinase Tcr mutant form
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000016051 ! antigen peptide transporter 1
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000016052 ! antigen peptide transporter 2
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000016053 ! tapasin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000016156 ! telethonin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000016261 ! serotransferrin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000016301 ! tyrosine 3-monooxygenase
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000016450 ! transmembrane protease serine 11D
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000016542 ! DNA topoisomerase 1
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000016798 ! titin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000016876 ! thymidylate synthase
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000016964 ! ubiquitin D
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000017272 ! vinculin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000017283 ! vitamin D3 receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000021998 ! neurotrophin
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000021999 ! death receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000022358 ! adenylate cyclase
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000024025 ! methyl-accepting chemotaxis protein IV
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000024067 ! homoserine kinase
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000024990 ! type II interferon
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000025845 ! ephrin receptor
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000025848 ! type I interferon
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000029189 ! AKT kinase
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000029394 ! ATP-dependent RNA helicase DDX58
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
+id: PR:000037070 ! phosphoprotein
+is_a: CHEBI:36080 {is_inferred="true"} ! protein
+
+[Term]
 id: UBERON:0001289 ! descending limb of loop of Henle
 is_a: UBERON:0004810 {is_inferred="true"} ! nephron tubule epithelium
 
------------------------------------------------------------------------
r38119 | hjd | 2017-01-17 11:29:06 -0800 (Tue, 17 Jan 2017) | 2 lines

removed charges from plant enzyme activities

changes in entailments

------------------------------------------------------------------------
r38115 | termgenie | 2017-01-17 08:57:41 -0800 (Tue, 17 Jan 2017) | 2 lines

TermGenie commit for user: hbye reviewed by ukemi

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38115)
+++ go_inferences.obo	(working copy)
@@ -89174,6 +89174,59 @@
 is_a: GO:1905822 {is_inferred="true"} ! regulation of mitotic sister chromatid arm separation
 
 [Term]
+id: GO:1905825 ! regulation of selenocysteine metabolic process
+is_a: GO:0006521 {is_inferred="true"} ! regulation of cellular amino acid metabolic process
+
+[Term]
+id: GO:1905826 ! negative regulation of selenocysteine metabolic process
+is_a: GO:0045763 {is_inferred="true"} ! negative regulation of cellular amino acid metabolic process
+is_a: GO:1905825 {is_inferred="true"} ! regulation of selenocysteine metabolic process
+
+[Term]
+id: GO:1905827 ! positive regulation of selenocysteine metabolic process
+is_a: GO:0045764 {is_inferred="true"} ! positive regulation of cellular amino acid metabolic process
+is_a: GO:1905825 {is_inferred="true"} ! regulation of selenocysteine metabolic process
+
+[Term]
+id: GO:1905828 ! regulation of prostaglandin catabolic process
+is_a: GO:0019217 {is_inferred="true"} ! regulation of fatty acid metabolic process
+is_a: GO:0031329 {is_inferred="true"} ! regulation of cellular catabolic process
+is_a: GO:0050994 {is_inferred="true"} ! regulation of lipid catabolic process
+
+[Term]
+id: GO:1905829 ! negative regulation of prostaglandin catabolic process
+is_a: GO:0031330 {is_inferred="true"} ! negative regulation of cellular catabolic process
+is_a: GO:0045922 {is_inferred="true"} ! negative regulation of fatty acid metabolic process
+is_a: GO:0050995 {is_inferred="true"} ! negative regulation of lipid catabolic process
+is_a: GO:1905828 {is_inferred="true"} ! regulation of prostaglandin catabolic process
+
+[Term]
+id: GO:1905830 ! positive regulation of prostaglandin catabolic process
+is_a: GO:0031331 {is_inferred="true"} ! positive regulation of cellular catabolic process
+is_a: GO:0045923 {is_inferred="true"} ! positive regulation of fatty acid metabolic process
+is_a: GO:0050996 {is_inferred="true"} ! positive regulation of lipid catabolic process
+is_a: GO:1905828 {is_inferred="true"} ! regulation of prostaglandin catabolic process
+
+[Term]
+id: GO:1905831 ! negative regulation of spindle assembly
+is_a: GO:0010948 {is_inferred="true"} ! negative regulation of cell cycle process
+is_a: GO:0051494 {is_inferred="true"} ! negative regulation of cytoskeleton organization
+is_a: GO:0090169 {is_inferred="true"} ! regulation of spindle assembly
+is_a: GO:1902116 {is_inferred="true"} ! negative regulation of organelle assembly
+
+[Term]
+id: GO:1905832 ! positive regulation of spindle assembly
+is_a: GO:0051495 {is_inferred="true"} ! positive regulation of cytoskeleton organization
+is_a: GO:0090068 {is_inferred="true"} ! positive regulation of cell cycle process
+is_a: GO:0090169 {is_inferred="true"} ! regulation of spindle assembly
+is_a: GO:1902117 {is_inferred="true"} ! positive regulation of organelle assembly
+
+[Term]
+id: GO:1905833 ! negative regulation of microtubule nucleation
+is_a: GO:0010968 {is_inferred="true"} ! regulation of microtubule nucleation
+is_a: GO:0031115 {is_inferred="true"} ! negative regulation of microtubule polymerization
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r38098 | hjd | 2017-01-16 13:49:51 -0800 (Mon, 16 Jan 2017) | 2 lines

added for plant enzyme activities for metacyc mapping project

changes in entailments

------------------------------------------------------------------------
r38098 | hjd | 2017-01-16 13:49:51 -0800 (Mon, 16 Jan 2017) | 2 lines

added for plant enzyme activities for metacyc mapping project

changes in entailments

------------------------------------------------------------------------
r38095 | hjd | 2017-01-16 12:24:54 -0800 (Mon, 16 Jan 2017) | 2 lines

more plant enzymes; total 43 for the day.

changes in entailments

------------------------------------------------------------------------
r38093 | hjd | 2017-01-16 12:06:29 -0800 (Mon, 16 Jan 2017) | 2 lines

added more plant enzymes

changes in entailments

------------------------------------------------------------------------
r38091 | hjd | 2017-01-16 11:32:18 -0800 (Mon, 16 Jan 2017) | 2 lines

added 4 plant enzyme terms

changes in entailments

------------------------------------------------------------------------
r38089 | dph | 2017-01-16 09:51:31 -0800 (Mon, 16 Jan 2017) | 2 lines

GH12921-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38089)
+++ go_inferences.obo	(working copy)
@@ -79563,7 +79563,8 @@
 
 [Term]
 id: GO:1903830 ! magnesium ion transmembrane transport
-is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
+is_a: GO:0015693 {is_inferred="true"} ! magnesium ion transport
+is_a: GO:0098662 {is_inferred="true"} ! inorganic cation transmembrane transport
 
 [Term]
 id: GO:1903831 ! signal transduction involved in cellular response to ammonium ion
@@ -89893,6 +89894,10 @@
 is_a: GO:0007006 {is_inferred="true"} ! mitochondrial membrane organization
 
 [Term]
+id: GO:1990614 ! mitochondrial magnesium ion transmembrane transport
+is_a: GO:0045016 {is_inferred="true"} ! mitochondrial magnesium ion transport
+
+[Term]
 id: GO:1990621 ! Vps4-Vta1 complex
 is_a: GO:0044440 {is_inferred="true"} ! endosomal part
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
------------------------------------------------------------------------
r38087 | dph | 2017-01-16 09:25:19 -0800 (Mon, 16 Jan 2017) | 2 lines

GH12888-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38087)
+++ go_inferences.obo	(working copy)
@@ -55352,7 +55352,7 @@
 
 [Term]
 id: GO:0080093 ! regulation of photorespiration
-is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
+is_a: GO:0031323 {is_inferred="true"} ! regulation of cellular metabolic process
 
 [Term]
 id: GO:0080094 ! response to trehalose-6-phosphate
------------------------------------------------------------------------
r38085 | termgenie | 2017-01-16 09:01:46 -0800 (Mon, 16 Jan 2017) | 4 lines

TermGenie commit for user: zebrafishembryo reviewed by ukemi

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38085)
+++ go_inferences.obo	(working copy)
@@ -89159,6 +89159,20 @@
 is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
 
 [Term]
+id: GO:1905822 ! regulation of mitotic sister chromatid arm separation
+is_a: GO:0010965 {is_inferred="true"} ! regulation of mitotic sister chromatid separation
+
+[Term]
+id: GO:1905823 ! negative regulation of mitotic sister chromatid arm separation
+is_a: GO:1905822 {is_inferred="true"} ! regulation of mitotic sister chromatid arm separation
+is_a: GO:2000816 {is_inferred="true"} ! negative regulation of mitotic sister chromatid separation
+
+[Term]
+id: GO:1905824 ! positive regulation of mitotic sister chromatid arm separation
+is_a: GO:1901970 {is_inferred="true"} ! positive regulation of mitotic sister chromatid separation
+is_a: GO:1905822 {is_inferred="true"} ! regulation of mitotic sister chromatid arm separation
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r38083 | paola | 2017-01-16 07:56:38 -0800 (Mon, 16 Jan 2017) | 2 lines

GH TPV single stranded and double stranded DNA binding #12130 - closed, see ticket for details

changes in entailments

------------------------------------------------------------------------
r38077 | paola | 2017-01-16 04:08:34 -0800 (Mon, 16 Jan 2017) | 3 lines

GH TPV single stranded and double stranded DNA binding #12130 - work in progress, see ticket for details

changes in entailments

------------------------------------------------------------------------
r38075 | davidos | 2017-01-16 03:35:54 -0800 (Mon, 16 Jan 2017) | 1 line

Fixed missing classification on microtubule-based process GO:0007017

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38075)
+++ go_inferences.obo	(working copy)
@@ -429,7 +429,6 @@
 [Term]
 id: GO:0000212 ! meiotic spindle organization
 is_a: GO:0007051 {is_inferred="true"} ! spindle organization
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
@@ -459,7 +458,6 @@
 [Term]
 id: GO:0000226 ! microtubule cytoskeleton organization
 is_a: GO:0007010 {is_inferred="true"} ! cytoskeleton organization
-is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
 [Term]
 id: GO:0000227 ! oxaloacetate secondary active transmembrane transporter activity
@@ -764,10 +762,6 @@
 is_a: GO:0000735 {is_inferred="true"} ! removal of nonhomologous ends
 
 [Term]
-id: GO:0000740 ! nuclear membrane fusion
-is_a: GO:0000741 {is_inferred="true"} ! karyogamy
-
-[Term]
 id: GO:0000741 ! karyogamy
 is_a: GO:0048284 {is_inferred="true"} ! organelle fusion
 
@@ -4536,6 +4530,10 @@
 is_a: GO:0030010 {is_inferred="true"} ! establishment of cell polarity
 
 [Term]
+id: GO:0003425 ! establishment of mitotic spindle orientation involved in growth plate cartilage chondrocyte division
+is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
+
+[Term]
 id: GO:0003426 ! cytoskeleton polarization involved in growth plate cartilage chondrocyte division
 is_a: GO:0030952 {is_inferred="true"} ! establishment or maintenance of cytoskeleton polarity
 
@@ -4604,6 +4602,10 @@
 is_a: GO:0038023 {is_inferred="true"} ! signaling receptor activity
 
 [Term]
+id: GO:0004971 ! AMPA glutamate receptor activity
+is_a: GO:0099094 {is_inferred="true"} ! ligand-gated cation channel activity
+
+[Term]
 id: GO:0004972 ! NMDA glutamate receptor activity
 is_a: GO:0099094 {is_inferred="true"} ! ligand-gated cation channel activity
 
@@ -7790,12 +7792,9 @@
 is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
 [Term]
-id: GO:0007017 ! microtubule-based process
-is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
-
-[Term]
 id: GO:0007019 ! microtubule depolymerization
 is_a: GO:0097435 {is_inferred="true"} ! supramolecular fiber organization
+is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
 [Term]
 id: GO:0007026 ! negative regulation of microtubule depolymerization
@@ -8381,7 +8380,7 @@
 
 [Term]
 id: GO:0008103 ! oocyte microtubule cytoskeleton polarization
-is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
+is_a: GO:0022414 {is_inferred="true"} ! reproductive process
 
 [Term]
 id: GO:0008142 ! oxysterol binding
@@ -8539,7 +8538,7 @@
 
 [Term]
 id: GO:0008328 ! ionotropic glutamate receptor complex
-is_a: GO:0034703 {is_inferred="true"} ! cation channel complex
+is_a: GO:0034702 {is_inferred="true"} ! ion channel complex
 is_a: GO:0098802 {is_inferred="true"} ! plasma membrane receptor complex
 is_a: GO:0098878 {is_inferred="true"} ! neurotransmitter receptor complex
 
@@ -14357,7 +14356,7 @@
 
 [Term]
 id: GO:0015277 ! kainate selective glutamate receptor activity
-is_a: GO:0005249 {is_inferred="true"} ! voltage-gated potassium channel activity
+is_a: GO:0005267 {is_inferred="true"} ! potassium channel activity
 is_a: GO:0005272 {is_inferred="true"} ! sodium channel activity
 is_a: GO:0099094 {is_inferred="true"} ! ligand-gated cation channel activity
 
@@ -16634,6 +16633,10 @@
 is_a: GO:0098798 {is_inferred="true"} ! mitochondrial protein complex
 
 [Term]
+id: GO:0017146 ! NMDA selective glutamate receptor complex
+is_a: GO:0034703 {is_inferred="true"} ! cation channel complex
+
+[Term]
 id: GO:0017148 ! negative regulation of translation
 is_a: GO:0006417 {is_inferred="true"} ! regulation of translation
 is_a: GO:0010629 {is_inferred="true"} ! negative regulation of gene expression
@@ -19295,6 +19298,10 @@
 is_a: GO:0000226 {is_inferred="true"} ! microtubule cytoskeleton organization
 
 [Term]
+id: GO:0021816 ! extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration
+is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
+
+[Term]
 id: GO:0021822 ! negative regulation of cell motility involved in cerebral cortex radial glia guided migration
 is_a: GO:1903976 {is_inferred="true"} ! negative regulation of glial cell migration
 
@@ -20950,6 +20957,10 @@
 is_a: GO:0031122 {is_inferred="true"} ! cytoplasmic microtubule organization
 
 [Term]
+id: GO:0030954 ! astral microtubule nucleation
+is_a: GO:0051418 {is_inferred="true"} ! microtubule nucleation by microtubule organizing center
+
+[Term]
 id: GO:0030955 ! potassium ion binding
 is_a: GO:0031420 {is_inferred="true"} ! alkali metal ion binding
 
@@ -21065,6 +21076,7 @@
 id: GO:0031025 ! equatorial microtubule organizing center disassembly
 is_a: GO:0022411 {is_inferred="true"} ! cellular component disassembly
 is_a: GO:0031023 {is_inferred="true"} ! microtubule organizing center organization
+is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
 [Term]
 id: GO:0031026 ! glutamate synthase complex
@@ -21224,6 +21236,7 @@
 [Term]
 id: GO:0031122 ! cytoplasmic microtubule organization
 is_a: GO:0097435 {is_inferred="true"} ! supramolecular fiber organization
+is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
 [Term]
 id: GO:0031135 ! negative regulation of conjugation
@@ -22755,7 +22768,6 @@
 
 [Term]
 id: GO:0032118 ! horsetail-astral microtubule organization
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
@@ -22767,7 +22779,6 @@
 
 [Term]
 id: GO:0032121 ! meiotic attachment of telomeric heterochromatin to spindle pole body
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
@@ -23139,6 +23150,10 @@
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 
 [Term]
+id: GO:0032281 ! AMPA glutamate receptor complex
+is_a: GO:0034703 {is_inferred="true"} ! cation channel complex
+
+[Term]
 id: GO:0032282 ! plastid acetyl-CoA carboxylase complex
 is_a: GO:0009317 {is_inferred="true"} ! acetyl-CoA carboxylase complex
 is_a: GO:0044435 {is_inferred="true"} ! plastid part
@@ -25100,7 +25115,7 @@
 
 [Term]
 id: GO:0032983 ! kainate selective glutamate receptor complex
-is_a: GO:0008076 {is_inferred="true"} ! voltage-gated potassium channel complex
+is_a: GO:0034705 {is_inferred="true"} ! potassium channel complex
 is_a: GO:0034706 {is_inferred="true"} ! sodium channel complex
 
 [Term]
@@ -28294,7 +28309,7 @@
 
 [Term]
 id: GO:0035044 ! sperm aster formation
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0022414 {is_inferred="true"} ! reproductive process
 
 [Term]
 id: GO:0035045 ! sperm plasma membrane disassembly
@@ -28348,6 +28363,10 @@
 is_a: GO:1901654 {is_inferred="true"} ! response to ketone
 
 [Term]
+id: GO:0035082 ! axoneme assembly
+is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
+
+[Term]
 id: GO:0035091 ! phosphatidylinositol binding
 is_a: GO:0005543 {is_inferred="true"} ! phospholipid binding
 
@@ -30074,6 +30093,10 @@
 is_a: GO:0044464 {is_inferred="true"} ! cell part
 
 [Term]
+id: GO:0036376 ! sodium ion export from cell
+is_a: GO:0071436 {is_inferred="true"} ! sodium ion export
+
+[Term]
 id: GO:0036378 ! calcitriol biosynthetic process from calciol
 is_a: GO:0042368 {is_inferred="true"} ! vitamin D biosynthetic process
 is_a: GO:0046173 {is_inferred="true"} ! polyol biosynthetic process
@@ -40467,6 +40490,7 @@
 [Term]
 id: GO:0046785 ! microtubule polymerization
 is_a: GO:0097435 {is_inferred="true"} ! supramolecular fiber organization
+is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
 [Term]
 id: GO:0046807 ! viral scaffold assembly and maintenance
@@ -43462,6 +43486,7 @@
 [Term]
 id: GO:0051229 ! meiotic spindle disassembly
 is_a: GO:0000212 {is_inferred="true"} ! meiotic spindle organization
+is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:0051230 {is_inferred="true"} ! spindle disassembly
 
 [Term]
@@ -43470,7 +43495,6 @@
 
 [Term]
 id: GO:0051232 ! meiotic spindle elongation
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:0051231 {is_inferred="true"} ! spindle elongation
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
@@ -43522,7 +43546,6 @@
 
 [Term]
 id: GO:0051257 ! meiotic spindle midzone assembly
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:0051255 {is_inferred="true"} ! spindle midzone assembly
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
@@ -43587,11 +43610,9 @@
 [Term]
 id: GO:0051293 ! establishment of spindle localization
 is_a: GO:0051653 {is_inferred="true"} ! spindle localization
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 
 [Term]
 id: GO:0051295 ! establishment of meiotic spindle localization
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:0051293 {is_inferred="true"} ! establishment of spindle localization
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
@@ -43874,6 +43895,18 @@
 is_a: GO:1901654 {is_inferred="true"} ! response to ketone
 
 [Term]
+id: GO:0051415 ! interphase microtubule nucleation by interphase microtubule organizing center
+is_a: GO:0051418 {is_inferred="true"} ! microtubule nucleation by microtubule organizing center
+
+[Term]
+id: GO:0051417 ! microtubule nucleation by spindle pole body
+is_a: GO:0051418 {is_inferred="true"} ! microtubule nucleation by microtubule organizing center
+
+[Term]
+id: GO:0051418 ! microtubule nucleation by microtubule organizing center
+is_a: GO:0007020 {is_inferred="true"} ! microtubule nucleation
+
+[Term]
 id: GO:0051421 ! regulation of endo-1,4-beta-xylanase activity
 is_a: GO:0051336 {is_inferred="true"} ! regulation of hydrolase activity
 
@@ -45896,7 +45929,6 @@
 [Term]
 id: GO:0060152 ! microtubule-based peroxisome localization
 is_a: GO:0007017 {is_inferred="true"} ! microtubule-based process
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 
 [Term]
 id: GO:0060159 ! regulation of dopamine receptor signaling pathway
@@ -47022,10 +47054,6 @@
 is_a: GO:1903320 {is_inferred="true"} ! regulation of protein modification by small protein conjugation or removal
 
 [Term]
-id: GO:0060626 ! regulation of cullin deneddylation
-is_a: GO:0060625 {is_inferred="true"} ! regulation of protein deneddylation
-
-[Term]
 id: GO:0060628 ! regulation of ER to Golgi vesicle-mediated transport
 is_a: GO:0032386 {is_inferred="true"} ! regulation of intracellular transport
 is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
@@ -49065,7 +49093,7 @@
 
 [Term]
 id: GO:0061763 ! multivesicular body-lysosome fusion
-is_a: GO:0051469 {is_inferred="true"} ! vesicle fusion with vacuole
+is_a: GO:0090174 {is_inferred="true"} ! organelle membrane fusion
 
 [Term]
 id: GO:0061768 ! magnesium:sodium antiporter activity
@@ -56297,7 +56325,6 @@
 [Term]
 id: GO:0090172 ! microtubule cytoskeleton organization involved in homologous chromosome segregation
 is_a: GO:0000226 {is_inferred="true"} ! microtubule cytoskeleton organization
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
@@ -56514,6 +56541,10 @@
 is_a: GO:0022414 {is_inferred="true"} ! reproductive process
 
 [Term]
+id: GO:0090222 ! centrosome-templated microtubule nucleation
+is_a: GO:0051418 {is_inferred="true"} ! microtubule nucleation by microtubule organizing center
+
+[Term]
 id: GO:0090224 ! regulation of spindle organization
 is_a: GO:0010564 {is_inferred="true"} ! regulation of cell cycle process
 is_a: GO:0070507 {is_inferred="true"} ! regulation of microtubule cytoskeleton organization
@@ -58063,6 +58094,10 @@
 is_a: GO:0044422 {is_inferred="true"} ! organelle part
 
 [Term]
+id: GO:0097623 ! potassium ion export across plasma membrane
+is_a: GO:0098668 {is_inferred="true"} ! potassium ion export from cell
+
+[Term]
 id: GO:0097630 ! intrinsic component of omegasome membrane
 is_a: GO:0031300 {is_inferred="true"} ! intrinsic component of organelle membrane
 is_a: GO:0044424 {is_inferred="true"} ! intracellular part
@@ -58259,7 +58294,6 @@
 [Term]
 id: GO:0098534 ! centriole assembly
 is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
-is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
 [Term]
 id: GO:0098538 ! lumenal side of transport vesicle membrane
@@ -58548,6 +58582,14 @@
 is_a: GO:0098665 {is_inferred="true"} ! serotonin receptor complex
 
 [Term]
+id: GO:0098667 ! sodium ion export across plasma membrane
+is_a: GO:0036376 {is_inferred="true"} ! sodium ion export from cell
+
+[Term]
+id: GO:0098668 ! potassium ion export from cell
+is_a: GO:0071435 {is_inferred="true"} ! potassium ion export
+
+[Term]
 id: GO:0098700 ! neurotransmitter loading into synaptic vesicle
 is_a: GO:0006836 {is_inferred="true"} ! neurotransmitter transport
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
@@ -58972,7 +59014,6 @@
 
 [Term]
 id: GO:0098866 ! multivesicular body fusion to apical plasma membrane
-is_a: GO:0045026 {is_inferred="true"} ! plasma membrane fusion
 is_a: GO:0090174 {is_inferred="true"} ! organelle membrane fusion
 
 [Term]
@@ -59216,7 +59257,7 @@
 is_a: GO:0008088 {is_inferred="true"} ! axo-dendritic transport
 
 [Term]
-id: GO:0098932 ! disruption by virus of host cell wall petidoglycan during virus entry
+id: GO:0098932 ! disruption by virus of host cell wall peptidoglycan during virus entry
 is_a: GO:0098994 {is_inferred="true"} ! disruption of host cell envelope during viral entry
 
 [Term]
@@ -66904,22 +66945,22 @@
 
 [Term]
 id: GO:1901193 ! regulation of formation of translation preinitiation complex
-is_a: GO:0006446 {is_inferred="true"} ! regulation of translational initiation
 is_a: GO:0044087 {is_inferred="true"} ! regulation of cellular component biogenesis
 is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
+is_a: GO:1904688 {is_inferred="true"} ! regulation of cytoplasmic translational initiation
 
 [Term]
 id: GO:1901194 ! negative regulation of formation of translation preinitiation complex
-is_a: GO:0045947 {is_inferred="true"} ! negative regulation of translational initiation
 is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:1901193 {is_inferred="true"} ! regulation of formation of translation preinitiation complex
+is_a: GO:1904689 {is_inferred="true"} ! negative regulation of cytoplasmic translational initiation
 
 [Term]
 id: GO:1901195 ! positive regulation of formation of translation preinitiation complex
 is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
-is_a: GO:0045948 {is_inferred="true"} ! positive regulation of translational initiation
 is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 is_a: GO:1901193 {is_inferred="true"} ! regulation of formation of translation preinitiation complex
+is_a: GO:1904690 {is_inferred="true"} ! positive regulation of cytoplasmic translational initiation
 
 [Term]
 id: GO:1901196 ! positive regulation of calcium-mediated signaling involved in cellular response to salt stress
@@ -78224,7 +78265,6 @@
 [Term]
 id: GO:1903563 ! microtubule bundle formation involved in horsetail-astral microtubule organization
 is_a: GO:0001578 {is_inferred="true"} ! microtubule bundle formation
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
@@ -84119,7 +84159,7 @@
 id: GO:1904782 ! negative regulation of NMDA glutamate receptor activity
 is_a: GO:1900450 {is_inferred="true"} ! negative regulation of glutamate receptor signaling pathway
 is_a: GO:2000272 {is_inferred="true"} ! negative regulation of receptor activity
-is_a: GO:2000310 {is_inferred="true"} ! regulation of N-methyl-D-aspartate selective glutamate receptor activity
+is_a: GO:2000310 {is_inferred="true"} ! regulation of NMDA receptor activity
 is_a: GO:2001258 {is_inferred="true"} ! negative regulation of cation channel activity
 
 [Term]
@@ -84126,7 +84166,7 @@
 id: GO:1904783 ! positive regulation of NMDA glutamate receptor activity
 is_a: GO:1900451 {is_inferred="true"} ! positive regulation of glutamate receptor signaling pathway
 is_a: GO:2000273 {is_inferred="true"} ! positive regulation of receptor activity
-is_a: GO:2000310 {is_inferred="true"} ! regulation of N-methyl-D-aspartate selective glutamate receptor activity
+is_a: GO:2000310 {is_inferred="true"} ! regulation of NMDA receptor activity
 is_a: GO:2001259 {is_inferred="true"} ! positive regulation of cation channel activity
 
 [Term]
@@ -91616,13 +91656,13 @@
 is_a: GO:2000307 {is_inferred="true"} ! regulation of tumor necrosis factor (ligand) superfamily member 11 production
 
 [Term]
-id: GO:2000310 ! regulation of N-methyl-D-aspartate selective glutamate receptor activity
+id: GO:2000310 ! regulation of NMDA receptor activity
 is_a: GO:0099601 {is_inferred="true"} ! regulation of neurotransmitter receptor activity
 is_a: GO:1900449 {is_inferred="true"} ! regulation of glutamate receptor signaling pathway
 is_a: GO:2001257 {is_inferred="true"} ! regulation of cation channel activity
 
 [Term]
-id: GO:2000311 ! regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
+id: GO:2000311 ! regulation of AMPA receptor activity
 is_a: GO:0099601 {is_inferred="true"} ! regulation of neurotransmitter receptor activity
 is_a: GO:1900449 {is_inferred="true"} ! regulation of glutamate receptor signaling pathway
 is_a: GO:2001257 {is_inferred="true"} ! regulation of cation channel activity
@@ -94792,10 +94832,10 @@
 is_a: GO:2000966 {is_inferred="true"} ! regulation of cell wall polysaccharide catabolic process
 
 [Term]
-id: GO:2000969 ! positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
+id: GO:2000969 ! positive regulation of AMPA receptor activity
 is_a: GO:1900451 {is_inferred="true"} ! positive regulation of glutamate receptor signaling pathway
 is_a: GO:2000273 {is_inferred="true"} ! positive regulation of receptor activity
-is_a: GO:2000311 {is_inferred="true"} ! regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
+is_a: GO:2000311 {is_inferred="true"} ! regulation of AMPA receptor activity
 is_a: GO:2001259 {is_inferred="true"} ! positive regulation of cation channel activity
 
 [Term]
------------------------------------------------------------------------
r38067 | dph | 2017-01-15 07:59:27 -0800 (Sun, 15 Jan 2017) | 2 lines

GH12909-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38067)
+++ go_inferences.obo	(working copy)
@@ -90090,6 +90090,7 @@
 [Term]
 id: GO:1990913 ! sperm head plasma membrane
 is_a: GO:0097223 {is_inferred="true"} ! sperm part
+is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
 
 [Term]
 id: GO:1990914 ! integral component of periplasmic side of plasma membrane
------------------------------------------------------------------------
r38065 | dph | 2017-01-15 07:36:11 -0800 (Sun, 15 Jan 2017) | 2 lines

GH12916-closed, GH12918-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38065)
+++ go_inferences.obo	(working copy)
@@ -4576,10 +4576,6 @@
 is_a: GO:0003676 {is_inferred="true"} ! nucleic acid binding
 
 [Term]
-id: GO:0003682 ! chromatin binding
-is_a: GO:0044877 {is_inferred="true"} ! macromolecular complex binding
-
-[Term]
 id: GO:0003708 ! retinoic acid receptor activity
 is_a: GO:0038023 {is_inferred="true"} ! signaling receptor activity
 
@@ -6385,10 +6381,6 @@
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
 [Term]
-id: GO:0006325 ! chromatin organization
-is_a: GO:0043933 {is_inferred="true"} ! macromolecular complex subunit organization
-
-[Term]
 id: GO:0006334 ! nucleosome assembly
 is_a: GO:0065004 {is_inferred="true"} ! protein-DNA complex assembly
 
@@ -12755,7 +12747,6 @@
 [Term]
 id: GO:0010847 ! regulation of chromatin assembly
 is_a: GO:0001672 {is_inferred="true"} ! regulation of chromatin assembly or disassembly
-is_a: GO:0033044 {is_inferred="true"} ! regulation of chromosome organization
 is_a: GO:0044087 {is_inferred="true"} ! regulation of cellular component biogenesis
 
 [Term]
@@ -21846,7 +21837,6 @@
 id: GO:0031452 ! negative regulation of heterochromatin assembly
 is_a: GO:0031445 {is_inferred="true"} ! regulation of heterochromatin assembly
 is_a: GO:0045798 {is_inferred="true"} ! negative regulation of chromatin assembly or disassembly
-is_a: GO:2001251 {is_inferred="true"} ! negative regulation of chromosome organization
 
 [Term]
 id: GO:0031453 ! positive regulation of heterochromatin assembly
@@ -21853,7 +21843,6 @@
 is_a: GO:0031445 {is_inferred="true"} ! regulation of heterochromatin assembly
 is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
 is_a: GO:0045799 {is_inferred="true"} ! positive regulation of chromatin assembly or disassembly
-is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
 
 [Term]
 id: GO:0031455 ! glycine betaine metabolic process
@@ -21884,6 +21873,10 @@
 is_a: GO:0072337 {is_inferred="true"} ! modified amino acid transport
 
 [Term]
+id: GO:0031491 ! nucleosome binding
+is_a: GO:0044877 {is_inferred="true"} ! macromolecular complex binding
+
+[Term]
 id: GO:0031494 ! regulation of mating type switching
 is_a: GO:0010453 {is_inferred="true"} ! regulation of cell fate commitment
 is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
@@ -21902,11 +21895,11 @@
 
 [Term]
 id: GO:0031497 ! chromatin assembly
-is_a: GO:0065003 {is_inferred="true"} ! macromolecular complex assembly
+is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
 
 [Term]
 id: GO:0031498 ! chromatin disassembly
-is_a: GO:0032984 {is_inferred="true"} ! macromolecular complex disassembly
+is_a: GO:0022411 {is_inferred="true"} ! cellular component disassembly
 
 [Term]
 id: GO:0031501 ! mannosyltransferase complex
@@ -72298,7 +72291,7 @@
 
 [Term]
 id: GO:1902275 ! regulation of chromatin organization
-is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
+is_a: GO:0033044 {is_inferred="true"} ! regulation of chromosome organization
 
 [Term]
 id: GO:1902276 ! regulation of pancreatic amylase secretion
@@ -76090,7 +76083,6 @@
 is_a: GO:0045798 {is_inferred="true"} ! negative regulation of chromatin assembly or disassembly
 is_a: GO:1900050 {is_inferred="true"} ! negative regulation of histone exchange
 is_a: GO:1903097 {is_inferred="true"} ! regulation of CENP-A containing nucleosome assembly
-is_a: GO:2001251 {is_inferred="true"} ! negative regulation of chromosome organization
 
 [Term]
 id: GO:1903099 ! positive regulation of CENP-A containing nucleosome assembly
@@ -76098,7 +76090,6 @@
 is_a: GO:0045799 {is_inferred="true"} ! positive regulation of chromatin assembly or disassembly
 is_a: GO:1900051 {is_inferred="true"} ! positive regulation of histone exchange
 is_a: GO:1903097 {is_inferred="true"} ! regulation of CENP-A containing nucleosome assembly
-is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
 
 [Term]
 id: GO:1903100 ! 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process
@@ -86486,13 +86477,13 @@
 
 [Term]
 id: GO:1905268 ! negative regulation of chromatin organization
-is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:1902275 {is_inferred="true"} ! regulation of chromatin organization
+is_a: GO:2001251 {is_inferred="true"} ! negative regulation of chromosome organization
 
 [Term]
 id: GO:1905269 ! positive regulation of chromatin organization
-is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 is_a: GO:1902275 {is_inferred="true"} ! regulation of chromatin organization
+is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
 
 [Term]
 id: GO:1905270 ! Meynert cell differentiation
------------------------------------------------------------------------
r38059 | dph | 2017-01-14 12:13:54 -0800 (Sat, 14 Jan 2017) | 2 lines

GH12919-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38061)
+++ go_inferences.obo	(working copy)
@@ -13193,6 +13193,7 @@
 [Term]
 id: GO:0010965 ! regulation of mitotic sister chromatid separation
 is_a: GO:0033047 {is_inferred="true"} ! regulation of mitotic sister chromatid segregation
+is_a: GO:1905818 {is_inferred="true"} ! regulation of chromosome separation
 
 [Term]
 id: GO:0010966 ! regulation of phosphate transport
@@ -49284,17 +49285,14 @@
 [Term]
 id: GO:0070129 ! regulation of mitochondrial translation
 is_a: GO:0006417 {is_inferred="true"} ! regulation of translation
-is_a: GO:0010821 {is_inferred="true"} ! regulation of mitochondrion organization
 
 [Term]
 id: GO:0070130 ! negative regulation of mitochondrial translation
-is_a: GO:0010823 {is_inferred="true"} ! negative regulation of mitochondrion organization
 is_a: GO:0017148 {is_inferred="true"} ! negative regulation of translation
 is_a: GO:0070129 {is_inferred="true"} ! regulation of mitochondrial translation
 
 [Term]
 id: GO:0070131 ! positive regulation of mitochondrial translation
-is_a: GO:0010822 {is_inferred="true"} ! positive regulation of mitochondrion organization
 is_a: GO:0045727 {is_inferred="true"} ! positive regulation of translation
 is_a: GO:0070129 {is_inferred="true"} ! regulation of mitochondrial translation
 
@@ -70775,7 +70773,7 @@
 id: GO:1901970 ! positive regulation of mitotic sister chromatid separation
 is_a: GO:0010965 {is_inferred="true"} ! regulation of mitotic sister chromatid separation
 is_a: GO:0045840 {is_inferred="true"} ! positive regulation of mitotic nuclear division
-is_a: GO:0051984 {is_inferred="true"} ! positive regulation of chromosome segregation
+is_a: GO:1905820 {is_inferred="true"} ! positive regulation of chromosome separation
 is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
 
 [Term]
@@ -77397,7 +77395,7 @@
 is_a: GO:0045840 {is_inferred="true"} ! positive regulation of mitotic nuclear division
 is_a: GO:0051984 {is_inferred="true"} ! positive regulation of chromosome segregation
 is_a: GO:1903379 {is_inferred="true"} ! regulation of mitotic chromosome condensation
-is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
+is_a: GO:1905821 {is_inferred="true"} ! positive regulation of chromosome condensation
 
 [Term]
 id: GO:1903381 ! regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway
@@ -85849,19 +85847,19 @@
 [Term]
 id: GO:1905132 ! regulation of meiotic chromosome separation
 is_a: GO:0040020 {is_inferred="true"} ! regulation of meiotic nuclear division
-is_a: GO:0051983 {is_inferred="true"} ! regulation of chromosome segregation
+is_a: GO:1905818 {is_inferred="true"} ! regulation of chromosome separation
 
 [Term]
 id: GO:1905133 ! negative regulation of meiotic chromosome separation
 is_a: GO:0045835 {is_inferred="true"} ! negative regulation of meiotic nuclear division
-is_a: GO:0051985 {is_inferred="true"} ! negative regulation of chromosome segregation
 is_a: GO:1905132 {is_inferred="true"} ! regulation of meiotic chromosome separation
+is_a: GO:1905819 {is_inferred="true"} ! negative regulation of chromosome separation
 
 [Term]
 id: GO:1905134 ! positive regulation of meiotic chromosome separation
 is_a: GO:0045836 {is_inferred="true"} ! positive regulation of meiotic nuclear division
-is_a: GO:0051984 {is_inferred="true"} ! positive regulation of chromosome segregation
 is_a: GO:1905132 {is_inferred="true"} ! regulation of meiotic chromosome separation
+is_a: GO:1905820 {is_inferred="true"} ! positive regulation of chromosome separation
 
 [Term]
 id: GO:1905135 ! biotin import across plasma membrane
@@ -89080,6 +89078,56 @@
 is_a: GO:1905810 {is_inferred="true"} ! regulation of excitatory synapse disassembly
 
 [Term]
+id: GO:1905812 ! regulation of motor neuron axon guidance
+is_a: GO:1902667 {is_inferred="true"} ! regulation of axon guidance
+
+[Term]
+id: GO:1905813 ! negative regulation of motor neuron axon guidance
+is_a: GO:1902668 {is_inferred="true"} ! negative regulation of axon guidance
+is_a: GO:1905812 {is_inferred="true"} ! regulation of motor neuron axon guidance
+
+[Term]
+id: GO:1905814 ! positive regulation of motor neuron axon guidance
+is_a: GO:1902669 {is_inferred="true"} ! positive regulation of axon guidance
+is_a: GO:1905812 {is_inferred="true"} ! regulation of motor neuron axon guidance
+
+[Term]
+id: GO:1905815 ! regulation of dorsal/ventral axon guidance
+is_a: GO:1902667 {is_inferred="true"} ! regulation of axon guidance
+
+[Term]
+id: GO:1905816 ! negative regulation of dorsal/ventral axon guidance
+is_a: GO:1902668 {is_inferred="true"} ! negative regulation of axon guidance
+is_a: GO:1905815 {is_inferred="true"} ! regulation of dorsal/ventral axon guidance
+
+[Term]
+id: GO:1905817 ! positive regulation of dorsal/ventral axon guidance
+is_a: GO:1902669 {is_inferred="true"} ! positive regulation of axon guidance
+is_a: GO:1905815 {is_inferred="true"} ! regulation of dorsal/ventral axon guidance
+
+[Term]
+id: GO:1905818 ! regulation of chromosome separation
+is_a: GO:0010564 {is_inferred="true"} ! regulation of cell cycle process
+is_a: GO:0051983 {is_inferred="true"} ! regulation of chromosome segregation
+
+[Term]
+id: GO:1905819 ! negative regulation of chromosome separation
+is_a: GO:0010948 {is_inferred="true"} ! negative regulation of cell cycle process
+is_a: GO:0051985 {is_inferred="true"} ! negative regulation of chromosome segregation
+is_a: GO:1905818 {is_inferred="true"} ! regulation of chromosome separation
+
+[Term]
+id: GO:1905820 ! positive regulation of chromosome separation
+is_a: GO:0051984 {is_inferred="true"} ! positive regulation of chromosome segregation
+is_a: GO:0090068 {is_inferred="true"} ! positive regulation of cell cycle process
+is_a: GO:1905818 {is_inferred="true"} ! regulation of chromosome separation
+
+[Term]
+id: GO:1905821 ! positive regulation of chromosome condensation
+is_a: GO:0060623 {is_inferred="true"} ! regulation of chromosome condensation
+is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
@@ -94054,6 +94102,7 @@
 id: GO:2000816 ! negative regulation of mitotic sister chromatid separation
 is_a: GO:0010965 {is_inferred="true"} ! regulation of mitotic sister chromatid separation
 is_a: GO:0033048 {is_inferred="true"} ! negative regulation of mitotic sister chromatid segregation
+is_a: GO:1905819 {is_inferred="true"} ! negative regulation of chromosome separation
 
 [Term]
 id: GO:2000817 ! regulation of histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore
------------------------------------------------------------------------
r38044 | tberardi | 2017-01-13 13:53:44 -0800 (Fri, 13 Jan 2017) | 1 line

GH12895 def change and NTR: GO:0045251 electron transfer flavoprotein complex - def edits

changes in entailments

------------------------------------------------------------------------
r38042 | dph | 2017-01-13 09:28:55 -0800 (Fri, 13 Jan 2017) | 2 lines

GH12906-closed

changes in entailments

------------------------------------------------------------------------
r38040 | hjd | 2017-01-13 09:05:05 -0800 (Fri, 13 Jan 2017) | 2 lines

added plant enzyme termss

changes in entailments

------------------------------------------------------------------------
r38017 | dph | 2017-01-12 06:08:51 -0800 (Thu, 12 Jan 2017) | 2 lines

GH12911-closed

changes in entailments

------------------------------------------------------------------------
r38017 | dph | 2017-01-12 06:08:51 -0800 (Thu, 12 Jan 2017) | 2 lines

GH12911-closed

changes in entailments

------------------------------------------------------------------------
r38014 | termgenie | 2017-01-11 18:43:27 -0800 (Wed, 11 Jan 2017) | 3 lines

TermGenie commit for user: tberardini reviewed by tberardini

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38015)
+++ go_inferences.obo	(working copy)
@@ -89071,6 +89071,15 @@
 is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 
 [Term]
+id: GO:1905810 ! regulation of excitatory synapse disassembly
+is_a: GO:1905806 {is_inferred="true"} ! regulation of synapse disassembly
+
+[Term]
+id: GO:1905811 ! negative regulation of excitatory synapse disassembly
+is_a: GO:1905807 {is_inferred="true"} ! negative regulation of synapse disassembly
+is_a: GO:1905810 {is_inferred="true"} ! regulation of excitatory synapse disassembly
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r38013 | tberardi | 2017-01-11 18:37:14 -0800 (Wed, 11 Jan 2017) | 1 line

removed extra spaces

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 38013)
+++ go_inferences.obo	(working copy)
@@ -45097,8 +45097,8 @@
 
 [Term]
 id: GO:0051964 ! negative regulation of synapse assembly
-is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:0051963 {is_inferred="true"} ! regulation of synapse assembly
+is_a: GO:1905809 {is_inferred="true"} ! negative regulation of synapse organization
 
 [Term]
 id: GO:0051965 ! positive regulation of synapse assembly
@@ -68945,7 +68945,7 @@
 
 [Term]
 id: GO:1901613 ! negative regulation of terminal button organization
-is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
+is_a: GO:1905809 {is_inferred="true"} ! negative regulation of synapse organization
 is_a: GO:2000331 {is_inferred="true"} ! regulation of terminal button organization
 
 [Term]
@@ -69004,8 +69004,8 @@
 
 [Term]
 id: GO:1901627 ! negative regulation of postsynaptic membrane organization
-is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:1901626 {is_inferred="true"} ! regulation of postsynaptic membrane organization
+is_a: GO:1905809 {is_inferred="true"} ! negative regulation of synapse organization
 
 [Term]
 id: GO:1901628 ! positive regulation of postsynaptic membrane organization
@@ -69018,8 +69018,8 @@
 
 [Term]
 id: GO:1901630 ! negative regulation of presynaptic membrane organization
-is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:1901629 {is_inferred="true"} ! regulation of presynaptic membrane organization
+is_a: GO:1905809 {is_inferred="true"} ! negative regulation of synapse organization
 
 [Term]
 id: GO:1901631 ! positive regulation of presynaptic membrane organization
@@ -82236,8 +82236,8 @@
 
 [Term]
 id: GO:1904397 ! negative regulation of neuromuscular junction development
-is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:1904396 {is_inferred="true"} ! regulation of neuromuscular junction development
+is_a: GO:1905809 {is_inferred="true"} ! negative regulation of synapse organization
 
 [Term]
 id: GO:1904398 ! positive regulation of neuromuscular junction development
@@ -88973,6 +88973,104 @@
 is_a: GO:0071539 {is_inferred="true"} ! protein localization to centrosome
 
 [Term]
+id: GO:1905794 ! response to puromycin
+is_a: GO:0014074 {is_inferred="true"} ! response to purine-containing compound
+is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
+
+[Term]
+id: GO:1905795 ! cellular response to puromycin
+is_a: GO:0071407 {is_inferred="true"} ! cellular response to organic cyclic compound
+is_a: GO:0071417 {is_inferred="true"} ! cellular response to organonitrogen compound
+is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
+is_a: GO:1905794 {is_inferred="true"} ! response to puromycin
+
+[Term]
+id: GO:1905796 ! regulation of intraciliary anterograde transport
+is_a: GO:0031344 {is_inferred="true"} ! regulation of cell projection organization
+is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
+is_a: GO:0033157 {is_inferred="true"} ! regulation of intracellular protein transport
+is_a: GO:0060632 {is_inferred="true"} ! regulation of microtubule-based movement
+
+[Term]
+id: GO:1905797 ! negative regulation of intraciliary anterograde transport
+is_a: GO:0010639 {is_inferred="true"} ! negative regulation of organelle organization
+is_a: GO:0031345 {is_inferred="true"} ! negative regulation of cell projection organization
+is_a: GO:0051271 {is_inferred="true"} ! negative regulation of cellular component movement
+is_a: GO:0090317 {is_inferred="true"} ! negative regulation of intracellular protein transport
+is_a: GO:1905796 {is_inferred="true"} ! regulation of intraciliary anterograde transport
+
+[Term]
+id: GO:1905798 ! positive regulation of intraciliary anterograde transport
+is_a: GO:0010638 {is_inferred="true"} ! positive regulation of organelle organization
+is_a: GO:0031346 {is_inferred="true"} ! positive regulation of cell projection organization
+is_a: GO:0051272 {is_inferred="true"} ! positive regulation of cellular component movement
+is_a: GO:0090316 {is_inferred="true"} ! positive regulation of intracellular protein transport
+is_a: GO:1905796 {is_inferred="true"} ! regulation of intraciliary anterograde transport
+
+[Term]
+id: GO:1905799 ! regulation of intraciliary retrograde transport
+is_a: GO:0031344 {is_inferred="true"} ! regulation of cell projection organization
+is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
+is_a: GO:0033157 {is_inferred="true"} ! regulation of intracellular protein transport
+is_a: GO:0060632 {is_inferred="true"} ! regulation of microtubule-based movement
+
+[Term]
+id: GO:1905800 ! negative regulation of intraciliary retrograde transport
+is_a: GO:0010639 {is_inferred="true"} ! negative regulation of organelle organization
+is_a: GO:0031345 {is_inferred="true"} ! negative regulation of cell projection organization
+is_a: GO:0051271 {is_inferred="true"} ! negative regulation of cellular component movement
+is_a: GO:0090317 {is_inferred="true"} ! negative regulation of intracellular protein transport
+is_a: GO:1905799 {is_inferred="true"} ! regulation of intraciliary retrograde transport
+
+[Term]
+id: GO:1905801 ! positive regulation of intraciliary retrograde transport
+is_a: GO:0010638 {is_inferred="true"} ! positive regulation of organelle organization
+is_a: GO:0031346 {is_inferred="true"} ! positive regulation of cell projection organization
+is_a: GO:0051272 {is_inferred="true"} ! positive regulation of cellular component movement
+is_a: GO:0090316 {is_inferred="true"} ! positive regulation of intracellular protein transport
+is_a: GO:1905799 {is_inferred="true"} ! regulation of intraciliary retrograde transport
+
+[Term]
+id: GO:1905802 ! regulation of cellular response to manganese ion
+is_a: GO:0048583 {is_inferred="true"} ! regulation of response to stimulus
+is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
+
+[Term]
+id: GO:1905803 ! negative regulation of cellular response to manganese ion
+is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
+is_a: GO:0048585 {is_inferred="true"} ! negative regulation of response to stimulus
+is_a: GO:1905802 {is_inferred="true"} ! regulation of cellular response to manganese ion
+
+[Term]
+id: GO:1905804 ! positive regulation of cellular response to manganese ion
+is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
+is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
+is_a: GO:1905802 {is_inferred="true"} ! regulation of cellular response to manganese ion
+
+[Term]
+id: GO:1905805 ! excitatory synapse disassembly
+is_a: GO:0098883 {is_inferred="true"} ! synapse disassembly
+
+[Term]
+id: GO:1905806 ! regulation of synapse disassembly
+is_a: GO:0050807 {is_inferred="true"} ! regulation of synapse organization
+
+[Term]
+id: GO:1905807 ! negative regulation of synapse disassembly
+is_a: GO:1905806 {is_inferred="true"} ! regulation of synapse disassembly
+is_a: GO:1905809 {is_inferred="true"} ! negative regulation of synapse organization
+
+[Term]
+id: GO:1905808 ! positive regulation of synapse disassembly
+is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
+is_a: GO:1905806 {is_inferred="true"} ! regulation of synapse disassembly
+
+[Term]
+id: GO:1905809 ! negative regulation of synapse organization
+is_a: GO:0050807 {is_inferred="true"} ! regulation of synapse organization
+is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
@@ -91400,9 +91498,9 @@
 
 [Term]
 id: GO:2000297 ! negative regulation of synapse maturation
-is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:0051961 {is_inferred="true"} ! negative regulation of nervous system development
 is_a: GO:0090128 {is_inferred="true"} ! regulation of synapse maturation
+is_a: GO:1905809 {is_inferred="true"} ! negative regulation of synapse organization
 
 [Term]
 id: GO:2000298 ! regulation of Rho-dependent protein serine/threonine kinase activity
------------------------------------------------------------------------
r38005 | tberardi | 2017-01-11 15:30:02 -0800 (Wed, 11 Jan 2017) | 1 line

third attempt

changes in entailments

------------------------------------------------------------------------
r37999 | dph | 2017-01-11 10:56:40 -0800 (Wed, 11 Jan 2017) | 2 lines

GH12888-partially completed.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37999)
+++ go_inferences.obo	(working copy)
@@ -17461,10 +17461,6 @@
 is_a: GO:0019637 {is_inferred="true"} ! organophosphate metabolic process
 
 [Term]
-id: GO:0019284 ! L-methionine biosynthetic process from S-adenosylmethionine
-is_a: GO:0046500 {is_inferred="true"} ! S-adenosylmethionine metabolic process
-
-[Term]
 id: GO:0019285 ! glycine betaine biosynthetic process from choline
 is_a: GO:0019695 {is_inferred="true"} ! choline metabolic process
 is_a: GO:0031456 {is_inferred="true"} ! glycine betaine biosynthetic process
------------------------------------------------------------------------
r37997 | dph | 2017-01-11 10:36:33 -0800 (Wed, 11 Jan 2017) | 2 lines

GH12898-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37997)
+++ go_inferences.obo	(working copy)
@@ -5316,10 +5316,6 @@
 is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
 
 [Term]
-id: GO:0005952 ! cAMP-dependent protein kinase complex
-is_a: GO:1902554 {is_inferred="true"} ! serine/threonine protein kinase complex
-
-[Term]
 id: GO:0005953 ! CAAX-protein geranylgeranyltransferase complex
 is_a: GO:1990234 {is_inferred="true"} ! transferase complex
 
------------------------------------------------------------------------
r37995 | paola | 2017-01-11 06:54:24 -0800 (Wed, 11 Jan 2017) | 5 lines

GH TPV single stranded and double stranded DNA binding #12130 - work in progress - added links:

changes in entailments

------------------------------------------------------------------------
r37989 | paola | 2017-01-11 05:01:44 -0800 (Wed, 11 Jan 2017) | 3 lines

GH NTR: spore-bearing structure development #12605 - closed - added ‘spore-bearing structure formation’

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37989)
+++ go_inferences.obo	(working copy)
@@ -58167,6 +58167,10 @@
 is_a: GO:0050880 {is_inferred="true"} ! regulation of blood vessel size
 
 [Term]
+id: GO:0097751 ! spore-bearing structure formation
+is_a: GO:0003006 {is_inferred="true"} ! developmental process involved in reproduction
+
+[Term]
 id: GO:0098003 ! viral tail assembly
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
 
------------------------------------------------------------------------
r37987 | paola | 2017-01-11 03:45:49 -0800 (Wed, 11 Jan 2017) | 3 lines

GH NTR: spore-bearing structure development #12605 - work in progress - edited ‘spore-bearing organ development’

changes in entailments

------------------------------------------------------------------------
r37982 | dph | 2017-01-10 13:29:59 -0800 (Tue, 10 Jan 2017) | 2 lines

GH12907-closed

changes in entailments

------------------------------------------------------------------------
r37977 | dph | 2017-01-10 09:13:52 -0800 (Tue, 10 Jan 2017) | 2 lines

Corrected logical definition for T cell aggregation. GH12904-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37977)
+++ go_inferences.obo	(working copy)
@@ -25440,17 +25440,8 @@
 is_a: GO:0009820 {is_inferred="true"} ! alkaloid metabolic process
 
 [Term]
-id: GO:0033077 ! T cell differentiation in thymus
-is_a: GO:0071594 {is_inferred="true"} ! thymocyte aggregation
-
-[Term]
-id: GO:0033080 ! immature T cell proliferation in thymus
-is_a: GO:0071594 {is_inferred="true"} ! thymocyte aggregation
-
-[Term]
 id: GO:0033081 ! regulation of T cell differentiation in thymus
 is_a: GO:0045580 {is_inferred="true"} ! regulation of T cell differentiation
-is_a: GO:2000398 {is_inferred="true"} ! regulation of thymocyte aggregation
 
 [Term]
 id: GO:0033082 ! regulation of extrathymic T cell differentiation
@@ -25469,7 +25460,6 @@
 id: GO:0033085 ! negative regulation of T cell differentiation in thymus
 is_a: GO:0033081 {is_inferred="true"} ! regulation of T cell differentiation in thymus
 is_a: GO:0045581 {is_inferred="true"} ! negative regulation of T cell differentiation
-is_a: GO:2000399 {is_inferred="true"} ! negative regulation of thymocyte aggregation
 
 [Term]
 id: GO:0033086 ! negative regulation of extrathymic T cell differentiation
@@ -25491,7 +25481,6 @@
 id: GO:0033089 ! positive regulation of T cell differentiation in thymus
 is_a: GO:0033081 {is_inferred="true"} ! regulation of T cell differentiation in thymus
 is_a: GO:0045582 {is_inferred="true"} ! positive regulation of T cell differentiation
-is_a: GO:2000400 {is_inferred="true"} ! positive regulation of thymocyte aggregation
 
 [Term]
 id: GO:0033090 ! positive regulation of extrathymic T cell differentiation
@@ -91918,18 +91907,15 @@
 
 [Term]
 id: GO:2000398 ! regulation of thymocyte aggregation
-is_a: GO:0002694 {is_inferred="true"} ! regulation of leukocyte activation
 is_a: GO:1903037 {is_inferred="true"} ! regulation of leukocyte cell-cell adhesion
 
 [Term]
 id: GO:2000399 ! negative regulation of thymocyte aggregation
-is_a: GO:0002695 {is_inferred="true"} ! negative regulation of leukocyte activation
 is_a: GO:1903038 {is_inferred="true"} ! negative regulation of leukocyte cell-cell adhesion
 is_a: GO:2000398 {is_inferred="true"} ! regulation of thymocyte aggregation
 
 [Term]
 id: GO:2000400 ! positive regulation of thymocyte aggregation
-is_a: GO:0002696 {is_inferred="true"} ! positive regulation of leukocyte activation
 is_a: GO:1903039 {is_inferred="true"} ! positive regulation of leukocyte cell-cell adhesion
 is_a: GO:2000398 {is_inferred="true"} ! regulation of thymocyte aggregation
 
------------------------------------------------------------------------
r37971 | termgenie | 2017-01-10 04:24:22 -0800 (Tue, 10 Jan 2017) | 2 lines

TermGenie commit for user: hattrill reviewed by ukemi

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37971)
+++ go_inferences.obo	(working copy)
@@ -88984,6 +88984,10 @@
 is_a: GO:1905790 {is_inferred="true"} ! regulation of mechanosensory behavior
 
 [Term]
+id: GO:1905793 ! protein localization to pericentriolar material
+is_a: GO:0071539 {is_inferred="true"} ! protein localization to centrosome
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37967 | dph | 2017-01-09 09:40:08 -0800 (Mon, 09 Jan 2017) | 2 lines

Replaced the directly negatively regulates relation with negatively regulates realtion between the decoy death receptor and the death receptor.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37967)
+++ go_inferences.obo	(working copy)
@@ -4618,7 +4618,7 @@
 
 [Term]
 id: GO:0005040 ! decoy death receptor activity
-is_a: GO:0030547 {is_inferred="true"} ! receptor inhibitor activity
+is_a: GO:0098772 {is_inferred="true"} ! molecular function regulator
 
 [Term]
 id: GO:0005043 ! netrin receptor activity involved in chemorepulsion
------------------------------------------------------------------------
r37965 | dph | 2017-01-09 09:33:07 -0800 (Mon, 09 Jan 2017) | 2 lines

GH12901-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37965)
+++ go_inferences.obo	(working copy)
@@ -4617,6 +4617,10 @@
 is_a: GO:0099589 {is_inferred="true"} ! serotonin receptor activity
 
 [Term]
+id: GO:0005040 ! decoy death receptor activity
+is_a: GO:0030547 {is_inferred="true"} ! receptor inhibitor activity
+
+[Term]
 id: GO:0005043 ! netrin receptor activity involved in chemorepulsion
 is_a: GO:0005042 {is_inferred="true"} ! netrin receptor activity
 
------------------------------------------------------------------------
r37963 | termgenie | 2017-01-09 07:51:27 -0800 (Mon, 09 Jan 2017) | 4 lines

TermGenie commit for user: hbye reviewed by ukemi

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37963)
+++ go_inferences.obo	(working copy)
@@ -88932,6 +88932,54 @@
 is_a: GO:0006337 {is_inferred="true"} ! nucleosome disassembly
 
 [Term]
+id: GO:1905784 ! regulation of anaphase-promoting complex-dependent catabolic process
+is_a: GO:0032434 {is_inferred="true"} ! regulation of proteasomal ubiquitin-dependent protein catabolic process
+
+[Term]
+id: GO:1905785 ! negative regulation of anaphase-promoting complex-dependent catabolic process
+is_a: GO:0032435 {is_inferred="true"} ! negative regulation of proteasomal ubiquitin-dependent protein catabolic process
+is_a: GO:1905784 {is_inferred="true"} ! regulation of anaphase-promoting complex-dependent catabolic process
+
+[Term]
+id: GO:1905786 ! positive regulation of anaphase-promoting complex-dependent catabolic process
+is_a: GO:0032436 {is_inferred="true"} ! positive regulation of proteasomal ubiquitin-dependent protein catabolic process
+is_a: GO:1905784 {is_inferred="true"} ! regulation of anaphase-promoting complex-dependent catabolic process
+
+[Term]
+id: GO:1905787 ! regulation of detection of mechanical stimulus involved in sensory perception of touch
+is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
+is_a: GO:0051931 {is_inferred="true"} ! regulation of sensory perception
+
+[Term]
+id: GO:1905788 ! negative regulation of detection of mechanical stimulus involved in sensory perception of touch
+is_a: GO:0031645 {is_inferred="true"} ! negative regulation of neurological system process
+is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
+is_a: GO:1905787 {is_inferred="true"} ! regulation of detection of mechanical stimulus involved in sensory perception of touch
+
+[Term]
+id: GO:1905789 ! positive regulation of detection of mechanical stimulus involved in sensory perception of touch
+is_a: GO:0031646 {is_inferred="true"} ! positive regulation of neurological system process
+is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
+is_a: GO:1905787 {is_inferred="true"} ! regulation of detection of mechanical stimulus involved in sensory perception of touch
+
+[Term]
+id: GO:1905790 ! regulation of mechanosensory behavior
+is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
+is_a: GO:0050795 {is_inferred="true"} ! regulation of behavior
+
+[Term]
+id: GO:1905791 ! negative regulation of mechanosensory behavior
+is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
+is_a: GO:0048521 {is_inferred="true"} ! negative regulation of behavior
+is_a: GO:1905790 {is_inferred="true"} ! regulation of mechanosensory behavior
+
+[Term]
+id: GO:1905792 ! positive regulation of mechanosensory behavior
+is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
+is_a: GO:0048520 {is_inferred="true"} ! positive regulation of behavior
+is_a: GO:1905790 {is_inferred="true"} ! regulation of mechanosensory behavior
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37924 | mcourtot | 2017-01-06 07:20:53 -0800 (Fri, 06 Jan 2017) | 1 line

removed uberon title

changes in entailments

------------------------------------------------------------------------
r37917 | tberardi | 2017-01-05 17:11:07 -0800 (Thu, 05 Jan 2017) | 1 line

GH12895 def change and NTR: GO:0045251 electron transfer flavoprotein complex - def change only, in progress

changes in entailments

------------------------------------------------------------------------
r37915 | tberardi | 2017-01-05 17:05:54 -0800 (Thu, 05 Jan 2017) | 1 line

GH#12889 ntr: Las1 Complex - closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37915)
+++ go_inferences.obo	(working copy)
@@ -57489,6 +57489,10 @@
 is_a: GO:0003002 {is_inferred="true"} ! regionalization
 
 [Term]
+id: GO:0090730 ! Las1 complex
+is_a: GO:0044445 {is_inferred="true"} ! cytosolic part
+
+[Term]
 id: GO:0093001 ! glycolysis from storage polysaccharide through glucose-1-phosphate
 is_a: GO:0000272 {is_inferred="true"} ! polysaccharide catabolic process
 is_a: GO:0061622 {is_inferred="true"} ! glycolytic process through glucose-1-phosphate
------------------------------------------------------------------------
r37913 | termgenie | 2017-01-05 08:54:12 -0800 (Thu, 05 Jan 2017) | 2 lines

TermGenie commit for user: ValWood reviewed by tberardini

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37913)
+++ go_inferences.obo	(working copy)
@@ -88924,6 +88924,10 @@
 is_a: GO:1905780 {is_inferred="true"} ! regulation of phosphatidylserine exposure on apoptotic cell surface
 
 [Term]
+id: GO:1905783 ! CENP-A containing nucleosome disassembly
+is_a: GO:0006337 {is_inferred="true"} ! nucleosome disassembly
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37907 | mcourtot | 2017-01-05 03:03:48 -0800 (Thu, 05 Jan 2017) | 1 line

renamed GO:0071629 ubiquitin-dependent of catabolism of misfolded proteins by cytoplasm-associated proteasome and GO:0071630 ubiquitin-dependent of catabolism of misfolded proteins by nucleus-associated proteasome as per https://github.com/geneontology/go-ontology/issues/12370

changes in entailments

------------------------------------------------------------------------
r37903 | tberardi | 2017-01-04 17:20:44 -0800 (Wed, 04 Jan 2017) | 1 line

GH12894 mp: GO:1904834 nuclear CENP-A containing chromatin - closed

changes in entailments

------------------------------------------------------------------------
r37900 | tberardi | 2017-01-04 17:09:23 -0800 (Wed, 04 Jan 2017) | 1 line

GH12892 Transcription occurs_in nuclear chromatin - closed

changes in entailments

------------------------------------------------------------------------
r37899 | tberardi | 2017-01-04 17:02:24 -0800 (Wed, 04 Jan 2017) | 1 line

GH#12887 TPV N-glycan processing - closed

changes in entailments

------------------------------------------------------------------------
r37895 | termgenie | 2017-01-04 09:10:07 -0800 (Wed, 04 Jan 2017) | 4 lines

TermGenie commit for user: vanaukenk reviewed by tberardini

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37895)
+++ go_inferences.obo	(working copy)
@@ -88906,6 +88906,24 @@
 is_a: GO:1905777 {is_inferred="true"} ! regulation of exonuclease activity
 
 [Term]
+id: GO:1905780 ! regulation of phosphatidylserine exposure on apoptotic cell surface
+is_a: GO:0097035 {is_inferred="true"} ! regulation of membrane lipid distribution
+is_a: GO:1900117 {is_inferred="true"} ! regulation of execution phase of apoptosis
+is_a: GO:1903729 {is_inferred="true"} ! regulation of plasma membrane organization
+
+[Term]
+id: GO:1905781 ! negative regulation of phosphatidylserine exposure on apoptotic cell surface
+is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
+is_a: GO:1900118 {is_inferred="true"} ! negative regulation of execution phase of apoptosis
+is_a: GO:1905780 {is_inferred="true"} ! regulation of phosphatidylserine exposure on apoptotic cell surface
+
+[Term]
+id: GO:1905782 ! positive regulation of phosphatidylserine exposure on apoptotic cell surface
+is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
+is_a: GO:1900119 {is_inferred="true"} ! positive regulation of execution phase of apoptosis
+is_a: GO:1905780 {is_inferred="true"} ! regulation of phosphatidylserine exposure on apoptotic cell surface
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37887 | cjm | 2017-01-03 13:57:12 -0800 (Tue, 03 Jan 2017) | 1 line

adding melanosome never in Caenorhabditis. https://github.com/geneontology/go-ontology/issues/12699

changes in entailments

------------------------------------------------------------------------
r37861 | davidos | 2016-12-31 09:18:24 -0800 (Sat, 31 Dec 2016) | 1 line

fixed bad xref

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37861)
+++ go_inferences.obo	(working copy)
@@ -4633,10 +4633,6 @@
 is_a: GO:0019966 {is_inferred="true"} ! interleukin-1 binding
 
 [Term]
-id: GO:0005224 ! ATP-binding and phosphorylation-dependent chloride channel activity
-is_a: GO:0099095 {is_inferred="true"} ! ligand-gated anion channel activity
-
-[Term]
 id: GO:0005231 ! excitatory extracellular ligand-gated ion channel activity
 is_a: GO:0004888 {is_inferred="true"} ! transmembrane signaling receptor activity
 
@@ -4649,8 +4645,9 @@
 is_a: GO:0099106 {is_inferred="true"} ! ion channel regulator activity
 
 [Term]
-id: GO:0005260 ! channel-conductance-controlling ATPase activity
-is_a: GO:0043225 {is_inferred="true"} ! ATPase-coupled anion transmembrane transporter activity
+id: GO:0005260 ! intracellular ATPase-gated chloride channel activity
+is_a: GO:0005254 {is_inferred="true"} ! chloride channel activity
+is_a: GO:0099095 {is_inferred="true"} ! ligand-gated anion channel activity
 
 [Term]
 id: GO:0005274 ! allantoin uptake transmembrane transporter activity
@@ -8047,6 +8044,18 @@
 is_a: GO:0051350 {is_inferred="true"} ! negative regulation of lyase activity
 
 [Term]
+id: GO:0007198 ! adenylate cyclase-inhibiting serotonin receptor signaling pathway
+is_a: GO:0098664 {is_inferred="true"} ! G-protein coupled serotonin receptor signaling pathway
+
+[Term]
+id: GO:0007208 ! phospholipase C-activating serotonin receptor signaling pathway
+is_a: GO:0098664 {is_inferred="true"} ! G-protein coupled serotonin receptor signaling pathway
+
+[Term]
+id: GO:0007210 ! serotonin receptor signaling pathway
+is_a: GO:0007165 {is_inferred="true"} ! signal transduction
+
+[Term]
 id: GO:0007213 ! G-protein coupled acetylcholine receptor signaling pathway
 is_a: GO:0095500 {is_inferred="true"} ! acetylcholine receptor signaling pathway
 
@@ -8538,7 +8547,7 @@
 
 [Term]
 id: GO:0008328 ! ionotropic glutamate receptor complex
-is_a: GO:0034702 {is_inferred="true"} ! ion channel complex
+is_a: GO:0034703 {is_inferred="true"} ! cation channel complex
 is_a: GO:0098802 {is_inferred="true"} ! plasma membrane receptor complex
 is_a: GO:0098878 {is_inferred="true"} ! neurotransmitter receptor complex
 
@@ -8694,6 +8703,10 @@
 is_a: GO:0022402 {is_inferred="true"} ! cell cycle process
 
 [Term]
+id: GO:0008610 ! lipid biosynthetic process
+is_a: GO:0006629 {is_inferred="true"} ! lipid metabolic process
+
+[Term]
 id: GO:0008611 ! ether lipid biosynthetic process
 is_a: GO:0046485 {is_inferred="true"} ! ether lipid metabolic process
 is_a: GO:0046504 {is_inferred="true"} ! glycerol ether biosynthetic process
@@ -14352,7 +14365,7 @@
 
 [Term]
 id: GO:0015277 ! kainate selective glutamate receptor activity
-is_a: GO:0005267 {is_inferred="true"} ! potassium channel activity
+is_a: GO:0005249 {is_inferred="true"} ! voltage-gated potassium channel activity
 is_a: GO:0005272 {is_inferred="true"} ! sodium channel activity
 is_a: GO:0099094 {is_inferred="true"} ! ligand-gated cation channel activity
 
@@ -16629,10 +16642,6 @@
 is_a: GO:0098798 {is_inferred="true"} ! mitochondrial protein complex
 
 [Term]
-id: GO:0017146 ! NMDA selective glutamate receptor complex
-is_a: GO:0034703 {is_inferred="true"} ! cation channel complex
-
-[Term]
 id: GO:0017148 ! negative regulation of translation
 is_a: GO:0006417 {is_inferred="true"} ! regulation of translation
 is_a: GO:0010629 {is_inferred="true"} ! negative regulation of gene expression
@@ -19567,7 +19576,7 @@
 is_a: GO:0099604 {is_inferred="true"} ! ligand-gated calcium channel activity
 
 [Term]
-id: GO:0022850 ! serotonin-gated cation channel activity
+id: GO:0022850 ! serotonin-gated cation-selective channel activity
 is_a: GO:0099589 {is_inferred="true"} ! serotonin receptor activity
 
 [Term]
@@ -25101,7 +25110,7 @@
 
 [Term]
 id: GO:0032983 ! kainate selective glutamate receptor complex
-is_a: GO:0034705 {is_inferred="true"} ! potassium channel complex
+is_a: GO:0008076 {is_inferred="true"} ! voltage-gated potassium channel complex
 is_a: GO:0034706 {is_inferred="true"} ! sodium channel complex
 
 [Term]
@@ -58542,6 +58551,19 @@
 is_a: GO:0098660 {is_inferred="true"} ! inorganic ion transmembrane transport
 
 [Term]
+id: GO:0098664 ! G-protein coupled serotonin receptor signaling pathway
+is_a: GO:0007186 {is_inferred="true"} ! G-protein coupled receptor signaling pathway
+is_a: GO:0007210 {is_inferred="true"} ! serotonin receptor signaling pathway
+
+[Term]
+id: GO:0098665 ! serotonin receptor complex
+is_a: GO:0043235 {is_inferred="true"} ! receptor complex
+
+[Term]
+id: GO:0098666 ! G-protein coupled serotonin receptor complex
+is_a: GO:0098665 {is_inferred="true"} ! serotonin receptor complex
+
+[Term]
 id: GO:0098700 ! neurotransmitter loading into synaptic vesicle
 is_a: GO:0006836 {is_inferred="true"} ! neurotransmitter transport
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
@@ -83254,7 +83276,8 @@
 [Term]
 id: GO:1904602 ! serotonin-activated cation-selective channel complex
 is_a: GO:0034703 {is_inferred="true"} ! cation channel complex
-is_a: GO:0043235 {is_inferred="true"} ! receptor complex
+is_a: GO:0098665 {is_inferred="true"} ! serotonin receptor complex
+is_a: GO:0098878 {is_inferred="true"} ! neurotransmitter receptor complex
 
 [Term]
 id: GO:1904603 ! regulation of advanced glycation end-product receptor activity
@@ -91386,9 +91409,9 @@
 
 [Term]
 id: GO:2000311 ! regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
-is_a: GO:0032412 {is_inferred="true"} ! regulation of ion transmembrane transporter activity
 is_a: GO:0099601 {is_inferred="true"} ! regulation of neurotransmitter receptor activity
 is_a: GO:1900449 {is_inferred="true"} ! regulation of glutamate receptor signaling pathway
+is_a: GO:2001257 {is_inferred="true"} ! regulation of cation channel activity
 
 [Term]
 id: GO:2000312 ! regulation of kainate selective glutamate receptor activity
@@ -94558,10 +94581,10 @@
 
 [Term]
 id: GO:2000969 ! positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
-is_a: GO:0032414 {is_inferred="true"} ! positive regulation of ion transmembrane transporter activity
 is_a: GO:1900451 {is_inferred="true"} ! positive regulation of glutamate receptor signaling pathway
 is_a: GO:2000273 {is_inferred="true"} ! positive regulation of receptor activity
 is_a: GO:2000311 {is_inferred="true"} ! regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
+is_a: GO:2001259 {is_inferred="true"} ! positive regulation of cation channel activity
 
 [Term]
 id: GO:2000970 ! regulation of detection of glucose
------------------------------------------------------------------------
r37789 | dph | 2016-12-23 05:30:42 -0800 (Fri, 23 Dec 2016) | 2 lines

Removed incorrect parent from GO:1905773 based on editors discussion yesterday.

changes in entailments

------------------------------------------------------------------------
r37784 | hjd | 2016-12-22 14:10:41 -0800 (Thu, 22 Dec 2016) | 2 lines

removed double quotes with two singles

changes in entailments

------------------------------------------------------------------------
r37782 | hjd | 2016-12-22 14:01:25 -0800 (Thu, 22 Dec 2016) | 2 lines

fixed weird truncated defs in plant activity terms

changes in entailments

------------------------------------------------------------------------
r37766 | dph | 2016-12-22 06:13:22 -0800 (Thu, 22 Dec 2016) | 2 lines

GH12885-closed.

changes in entailments

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r37766 | dph | 2016-12-22 06:13:22 -0800 (Thu, 22 Dec 2016) | 2 lines

GH12885-closed.

changes in entailments

------------------------------------------------------------------------
r37764 | dph | 2016-12-22 05:56:36 -0800 (Thu, 22 Dec 2016) | 2 lines

Modified GO:1905773 to try to make the reasoner place it correctly, but was unsuccessful. Instead, I remove the logical def and placed it manually in the ontology. GH12884-closed.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37764)
+++ go_inferences.obo	(working copy)
@@ -88852,10 +88852,6 @@
 is_a: GO:2000543 {is_inferred="true"} ! positive regulation of gastrulation
 
 [Term]
-id: GO:1905773 ! 8-hydroxy-2'-deoxyguanosine binding
-is_a: GO:0005488 {is_inferred="true"} ! binding
-
-[Term]
 id: GO:1905774 ! regulation of DNA helicase activity
 is_a: GO:0051095 {is_inferred="true"} ! regulation of helicase activity
 is_a: GO:1905462 {is_inferred="true"} ! regulation of DNA duplex unwinding
------------------------------------------------------------------------
r37762 | termgenie | 2016-12-22 05:36:24 -0800 (Thu, 22 Dec 2016) | 4 lines

TermGenie commit for user: NancyCampbell reviewed by ukemi

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37762)
+++ go_inferences.obo	(working copy)
@@ -70485,17 +70485,19 @@
 [Term]
 id: GO:1901917 ! regulation of exoribonuclease activity
 is_a: GO:0060700 {is_inferred="true"} ! regulation of ribonuclease activity
+is_a: GO:1905777 {is_inferred="true"} ! regulation of exonuclease activity
 
 [Term]
 id: GO:1901918 ! negative regulation of exoribonuclease activity
 is_a: GO:0060701 {is_inferred="true"} ! negative regulation of ribonuclease activity
 is_a: GO:1901917 {is_inferred="true"} ! regulation of exoribonuclease activity
+is_a: GO:1905778 {is_inferred="true"} ! negative regulation of exonuclease activity
 
 [Term]
 id: GO:1901919 ! positive regulation of exoribonuclease activity
-is_a: GO:0032075 {is_inferred="true"} ! positive regulation of nuclease activity
 is_a: GO:0051254 {is_inferred="true"} ! positive regulation of RNA metabolic process
 is_a: GO:1901917 {is_inferred="true"} ! regulation of exoribonuclease activity
+is_a: GO:1905779 {is_inferred="true"} ! positive regulation of exonuclease activity
 
 [Term]
 id: GO:1901920 ! peptidyl-tyrosine dephosphorylation involved in activation of protein kinase activity
@@ -72842,16 +72844,19 @@
 [Term]
 id: GO:1902392 ! regulation of exodeoxyribonuclease activity
 is_a: GO:0032070 {is_inferred="true"} ! regulation of deoxyribonuclease activity
+is_a: GO:1905777 {is_inferred="true"} ! regulation of exonuclease activity
 
 [Term]
 id: GO:1902393 ! negative regulation of exodeoxyribonuclease activity
 is_a: GO:0032076 {is_inferred="true"} ! negative regulation of deoxyribonuclease activity
 is_a: GO:1902392 {is_inferred="true"} ! regulation of exodeoxyribonuclease activity
+is_a: GO:1905778 {is_inferred="true"} ! negative regulation of exonuclease activity
 
 [Term]
 id: GO:1902394 ! positive regulation of exodeoxyribonuclease activity
 is_a: GO:0032077 {is_inferred="true"} ! positive regulation of deoxyribonuclease activity
 is_a: GO:1902392 {is_inferred="true"} ! regulation of exodeoxyribonuclease activity
+is_a: GO:1905779 {is_inferred="true"} ! positive regulation of exonuclease activity
 
 [Term]
 id: GO:1902395 ! regulation of 1-deoxy-D-xylulose-5-phosphate synthase activity
@@ -74675,12 +74680,12 @@
 
 [Term]
 id: GO:1902799 ! regulation of phosphodiesterase I activity
-is_a: GO:0032069 {is_inferred="true"} ! regulation of nuclease activity
+is_a: GO:1905777 {is_inferred="true"} ! regulation of exonuclease activity
 
 [Term]
 id: GO:1902800 ! positive regulation of phosphodiesterase I activity
-is_a: GO:0032075 {is_inferred="true"} ! positive regulation of nuclease activity
 is_a: GO:1902799 {is_inferred="true"} ! regulation of phosphodiesterase I activity
+is_a: GO:1905779 {is_inferred="true"} ! positive regulation of exonuclease activity
 
 [Term]
 id: GO:1902801 ! regulation of heterochromatin island assembly
@@ -88847,6 +88852,10 @@
 is_a: GO:2000543 {is_inferred="true"} ! positive regulation of gastrulation
 
 [Term]
+id: GO:1905773 ! 8-hydroxy-2'-deoxyguanosine binding
+is_a: GO:0005488 {is_inferred="true"} ! binding
+
+[Term]
 id: GO:1905774 ! regulation of DNA helicase activity
 is_a: GO:0051095 {is_inferred="true"} ! regulation of helicase activity
 is_a: GO:1905462 {is_inferred="true"} ! regulation of DNA duplex unwinding
@@ -88864,6 +88873,20 @@
 is_a: GO:1905774 {is_inferred="true"} ! regulation of DNA helicase activity
 
 [Term]
+id: GO:1905777 ! regulation of exonuclease activity
+is_a: GO:0032069 {is_inferred="true"} ! regulation of nuclease activity
+
+[Term]
+id: GO:1905778 ! negative regulation of exonuclease activity
+is_a: GO:0032074 {is_inferred="true"} ! negative regulation of nuclease activity
+is_a: GO:1905777 {is_inferred="true"} ! regulation of exonuclease activity
+
+[Term]
+id: GO:1905779 ! positive regulation of exonuclease activity
+is_a: GO:0032075 {is_inferred="true"} ! positive regulation of nuclease activity
+is_a: GO:1905777 {is_inferred="true"} ! regulation of exonuclease activity
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37758 | dph | 2016-12-21 12:57:50 -0800 (Wed, 21 Dec 2016) | 2 lines

GH12883-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37758)
+++ go_inferences.obo	(working copy)
@@ -16371,6 +16371,10 @@
 is_a: GO:0016241 {is_inferred="true"} ! regulation of macroautophagy
 
 [Term]
+id: GO:0016243 ! regulation of autophagosome size
+is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
+
+[Term]
 id: GO:0016247 ! channel regulator activity
 is_a: GO:0098772 {is_inferred="true"} ! molecular function regulator
 
------------------------------------------------------------------------
r37756 | dph | 2016-12-21 12:47:07 -0800 (Wed, 21 Dec 2016) | 2 lines

Checked terms and move appropriate terms under supramolecular fiber. GH12640-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37756)
+++ go_inferences.obo	(working copy)
@@ -19950,6 +19950,7 @@
 [Term]
 id: GO:0030239 ! myofibril assembly
 is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
+is_a: GO:0097435 {is_inferred="true"} ! supramolecular fiber organization
 
 [Term]
 id: GO:0030243 ! cellulose metabolic process
@@ -46249,6 +46250,7 @@
 is_a: GO:0051153 {is_inferred="true"} ! regulation of striated muscle cell differentiation
 is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
 is_a: GO:1902115 {is_inferred="true"} ! regulation of organelle assembly
+is_a: GO:1902903 {is_inferred="true"} ! regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0060298 ! positive regulation of sarcomere organization
@@ -46257,6 +46259,7 @@
 is_a: GO:0051495 {is_inferred="true"} ! positive regulation of cytoskeleton organization
 is_a: GO:0060297 {is_inferred="true"} ! regulation of sarcomere organization
 is_a: GO:1902117 {is_inferred="true"} ! positive regulation of organelle assembly
+is_a: GO:1902905 {is_inferred="true"} ! positive regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0060299 ! negative regulation of sarcomere organization
@@ -46265,6 +46268,7 @@
 is_a: GO:0051494 {is_inferred="true"} ! negative regulation of cytoskeleton organization
 is_a: GO:0060297 {is_inferred="true"} ! regulation of sarcomere organization
 is_a: GO:1902116 {is_inferred="true"} ! negative regulation of organelle assembly
+is_a: GO:1902904 {is_inferred="true"} ! negative regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0060300 ! regulation of cytokine activity
@@ -86640,6 +86644,7 @@
 is_a: GO:0032956 {is_inferred="true"} ! regulation of actin cytoskeleton organization
 is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
 is_a: GO:1902115 {is_inferred="true"} ! regulation of organelle assembly
+is_a: GO:1902903 {is_inferred="true"} ! regulation of supramolecular fiber organization
 is_a: GO:2000725 {is_inferred="true"} ! regulation of cardiac muscle cell differentiation
 
 [Term]
@@ -86647,6 +86652,7 @@
 is_a: GO:0010721 {is_inferred="true"} ! negative regulation of cell development
 is_a: GO:0051494 {is_inferred="true"} ! negative regulation of cytoskeleton organization
 is_a: GO:1902116 {is_inferred="true"} ! negative regulation of organelle assembly
+is_a: GO:1902904 {is_inferred="true"} ! negative regulation of supramolecular fiber organization
 is_a: GO:1905304 {is_inferred="true"} ! regulation of cardiac myofibril assembly
 is_a: GO:2000726 {is_inferred="true"} ! negative regulation of cardiac muscle cell differentiation
 
@@ -86655,6 +86661,7 @@
 is_a: GO:0010720 {is_inferred="true"} ! positive regulation of cell development
 is_a: GO:0051495 {is_inferred="true"} ! positive regulation of cytoskeleton organization
 is_a: GO:1902117 {is_inferred="true"} ! positive regulation of organelle assembly
+is_a: GO:1902905 {is_inferred="true"} ! positive regulation of supramolecular fiber organization
 is_a: GO:1905304 {is_inferred="true"} ! regulation of cardiac myofibril assembly
 is_a: GO:2000727 {is_inferred="true"} ! positive regulation of cardiac muscle cell differentiation
 
------------------------------------------------------------------------
r37754 | dph | 2016-12-21 12:23:04 -0800 (Wed, 21 Dec 2016) | 2 lines

Merged fibril into supramolecular fiber as part of GH12640.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37754)
+++ go_inferences.obo	(working copy)
@@ -33022,10 +33022,6 @@
 is_a: GO:0043200 {is_inferred="true"} ! response to amino acid
 
 [Term]
-id: GO:0043205 ! fibril
-is_a: GO:0044420 {is_inferred="true"} ! extracellular matrix component
-
-[Term]
 id: GO:0043208 ! glycosphingolipid binding
 is_a: GO:0046625 {is_inferred="true"} ! sphingolipid binding
 is_a: GO:0051861 {is_inferred="true"} ! glycolipid binding
------------------------------------------------------------------------
r37752 | termgenie | 2016-12-21 10:42:33 -0800 (Wed, 21 Dec 2016) | 4 lines

TermGenie commit for user: NancyCampbell reviewed by ukemi

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37752)
+++ go_inferences.obo	(working copy)
@@ -31884,16 +31884,14 @@
 
 [Term]
 id: GO:0042661 ! regulation of mesodermal cell fate specification
-is_a: GO:0010470 {is_inferred="true"} ! regulation of gastrulation
 is_a: GO:0042659 {is_inferred="true"} ! regulation of cell fate specification
-is_a: GO:2000380 {is_inferred="true"} ! regulation of mesoderm development
+is_a: GO:1905770 {is_inferred="true"} ! regulation of mesodermal cell differentiation
 
 [Term]
 id: GO:0042662 ! negative regulation of mesodermal cell fate specification
 is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
 is_a: GO:0042661 {is_inferred="true"} ! regulation of mesodermal cell fate specification
-is_a: GO:2000381 {is_inferred="true"} ! negative regulation of mesoderm development
-is_a: GO:2000542 {is_inferred="true"} ! negative regulation of gastrulation
+is_a: GO:1905771 {is_inferred="true"} ! negative regulation of mesodermal cell differentiation
 
 [Term]
 id: GO:0042663 ! regulation of endodermal cell fate specification
@@ -41304,29 +41302,25 @@
 [Term]
 id: GO:0048334 ! regulation of mesodermal cell fate determination
 is_a: GO:0010453 {is_inferred="true"} ! regulation of cell fate commitment
-is_a: GO:0010470 {is_inferred="true"} ! regulation of gastrulation
-is_a: GO:2000380 {is_inferred="true"} ! regulation of mesoderm development
+is_a: GO:1905770 {is_inferred="true"} ! regulation of mesodermal cell differentiation
 
 [Term]
 id: GO:0048335 ! negative regulation of mesodermal cell fate determination
 is_a: GO:0010454 {is_inferred="true"} ! negative regulation of cell fate commitment
 is_a: GO:0048334 {is_inferred="true"} ! regulation of mesodermal cell fate determination
-is_a: GO:2000381 {is_inferred="true"} ! negative regulation of mesoderm development
-is_a: GO:2000542 {is_inferred="true"} ! negative regulation of gastrulation
+is_a: GO:1905771 {is_inferred="true"} ! negative regulation of mesodermal cell differentiation
 
 [Term]
 id: GO:0048336 ! positive regulation of mesodermal cell fate determination
 is_a: GO:0010455 {is_inferred="true"} ! positive regulation of cell fate commitment
 is_a: GO:0048334 {is_inferred="true"} ! regulation of mesodermal cell fate determination
-is_a: GO:2000382 {is_inferred="true"} ! positive regulation of mesoderm development
-is_a: GO:2000543 {is_inferred="true"} ! positive regulation of gastrulation
+is_a: GO:1905772 {is_inferred="true"} ! positive regulation of mesodermal cell differentiation
 
 [Term]
 id: GO:0048337 ! positive regulation of mesodermal cell fate specification
 is_a: GO:0042660 {is_inferred="true"} ! positive regulation of cell fate specification
 is_a: GO:0042661 {is_inferred="true"} ! regulation of mesodermal cell fate specification
-is_a: GO:2000382 {is_inferred="true"} ! positive regulation of mesoderm development
-is_a: GO:2000543 {is_inferred="true"} ! positive regulation of gastrulation
+is_a: GO:1905772 {is_inferred="true"} ! positive regulation of mesodermal cell differentiation
 
 [Term]
 id: GO:0048339 ! paraxial mesoderm development
@@ -73109,22 +73103,19 @@
 [Term]
 id: GO:1902449 ! regulation of ATP-dependent DNA helicase activity
 is_a: GO:0043462 {is_inferred="true"} ! regulation of ATPase activity
-is_a: GO:0051095 {is_inferred="true"} ! regulation of helicase activity
-is_a: GO:1905462 {is_inferred="true"} ! regulation of DNA duplex unwinding
+is_a: GO:1905774 {is_inferred="true"} ! regulation of DNA helicase activity
 
 [Term]
 id: GO:1902450 ! negative regulation of ATP-dependent DNA helicase activity
 is_a: GO:0032780 {is_inferred="true"} ! negative regulation of ATPase activity
-is_a: GO:0051097 {is_inferred="true"} ! negative regulation of helicase activity
 is_a: GO:1902449 {is_inferred="true"} ! regulation of ATP-dependent DNA helicase activity
-is_a: GO:1905463 {is_inferred="true"} ! negative regulation of DNA duplex unwinding
+is_a: GO:1905775 {is_inferred="true"} ! negative regulation of DNA helicase activity
 
 [Term]
 id: GO:1902451 ! positive regulation of ATP-dependent DNA helicase activity
 is_a: GO:0032781 {is_inferred="true"} ! positive regulation of ATPase activity
-is_a: GO:0051096 {is_inferred="true"} ! positive regulation of helicase activity
 is_a: GO:1902449 {is_inferred="true"} ! regulation of ATP-dependent DNA helicase activity
-is_a: GO:1905464 {is_inferred="true"} ! positive regulation of DNA duplex unwinding
+is_a: GO:1905776 {is_inferred="true"} ! positive regulation of DNA helicase activity
 
 [Term]
 id: GO:1902455 ! negative regulation of stem cell population maintenance
@@ -88829,6 +88820,43 @@
 is_a: GO:1905767 {is_inferred="true"} ! regulation of double-stranded telomeric DNA binding
 
 [Term]
+id: GO:1905770 ! regulation of mesodermal cell differentiation
+is_a: GO:0010470 {is_inferred="true"} ! regulation of gastrulation
+is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
+is_a: GO:2000380 {is_inferred="true"} ! regulation of mesoderm development
+
+[Term]
+id: GO:1905771 ! negative regulation of mesodermal cell differentiation
+is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
+is_a: GO:1905770 {is_inferred="true"} ! regulation of mesodermal cell differentiation
+is_a: GO:2000381 {is_inferred="true"} ! negative regulation of mesoderm development
+is_a: GO:2000542 {is_inferred="true"} ! negative regulation of gastrulation
+
+[Term]
+id: GO:1905772 ! positive regulation of mesodermal cell differentiation
+is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
+is_a: GO:1905770 {is_inferred="true"} ! regulation of mesodermal cell differentiation
+is_a: GO:2000382 {is_inferred="true"} ! positive regulation of mesoderm development
+is_a: GO:2000543 {is_inferred="true"} ! positive regulation of gastrulation
+
+[Term]
+id: GO:1905774 ! regulation of DNA helicase activity
+is_a: GO:0051095 {is_inferred="true"} ! regulation of helicase activity
+is_a: GO:1905462 {is_inferred="true"} ! regulation of DNA duplex unwinding
+
+[Term]
+id: GO:1905775 ! negative regulation of DNA helicase activity
+is_a: GO:0051097 {is_inferred="true"} ! negative regulation of helicase activity
+is_a: GO:1905463 {is_inferred="true"} ! negative regulation of DNA duplex unwinding
+is_a: GO:1905774 {is_inferred="true"} ! regulation of DNA helicase activity
+
+[Term]
+id: GO:1905776 ! positive regulation of DNA helicase activity
+is_a: GO:0051096 {is_inferred="true"} ! positive regulation of helicase activity
+is_a: GO:1905464 {is_inferred="true"} ! positive regulation of DNA duplex unwinding
+is_a: GO:1905774 {is_inferred="true"} ! regulation of DNA helicase activity
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37749 | dph | 2016-12-21 10:21:48 -0800 (Wed, 21 Dec 2016) | 2 lines

Renamed and defined the fibril organization terms to become supramolecular fiber organization terms. Also renamed and modified the regulation terms as part of GH12640.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37749)
+++ go_inferences.obo	(working copy)
@@ -7794,7 +7794,7 @@
 
 [Term]
 id: GO:0007015 ! actin filament organization
-is_a: GO:0016043 {is_inferred="true"} ! cellular component organization
+is_a: GO:0097435 {is_inferred="true"} ! supramolecular fiber organization
 
 [Term]
 id: GO:0007016 ! cytoskeletal anchoring at plasma membrane
@@ -7805,10 +7805,15 @@
 is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
 
 [Term]
+id: GO:0007019 ! microtubule depolymerization
+is_a: GO:0097435 {is_inferred="true"} ! supramolecular fiber organization
+
+[Term]
 id: GO:0007026 ! negative regulation of microtubule depolymerization
 is_a: GO:0031111 {is_inferred="true"} ! negative regulation of microtubule polymerization or depolymerization
 is_a: GO:0031114 {is_inferred="true"} ! regulation of microtubule depolymerization
 is_a: GO:1901880 {is_inferred="true"} ! negative regulation of protein depolymerization
+is_a: GO:1902904 {is_inferred="true"} ! negative regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0007027 ! negative regulation of axonemal microtubule depolymerization
@@ -8349,6 +8354,10 @@
 is_a: GO:0007423 {is_inferred="true"} ! sensory organ development
 
 [Term]
+id: GO:0008064 ! regulation of actin polymerization or depolymerization
+is_a: GO:1902903 {is_inferred="true"} ! regulation of supramolecular fiber organization
+
+[Term]
 id: GO:0008068 ! extracellular-glutamate-gated chloride channel activity
 is_a: GO:0099095 {is_inferred="true"} ! ligand-gated anion channel activity
 
@@ -8507,7 +8516,7 @@
 
 [Term]
 id: GO:0008302 ! female germline ring canal formation, actin assembly
-is_a: GO:0022414 {is_inferred="true"} ! reproductive process
+is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 
 [Term]
 id: GO:0008303 ! caspase complex
@@ -19837,6 +19846,7 @@
 [Term]
 id: GO:0030199 ! collagen fibril organization
 is_a: GO:0071822 {is_inferred="true"} ! protein complex subunit organization
+is_a: GO:0097435 {is_inferred="true"} ! supramolecular fiber organization
 
 [Term]
 id: GO:0030200 ! heparan sulfate proteoglycan catabolic process
@@ -20735,21 +20745,25 @@
 id: GO:0030835 ! negative regulation of actin filament depolymerization
 is_a: GO:0030834 {is_inferred="true"} ! regulation of actin filament depolymerization
 is_a: GO:1901880 {is_inferred="true"} ! negative regulation of protein depolymerization
+is_a: GO:1902904 {is_inferred="true"} ! negative regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0030836 ! positive regulation of actin filament depolymerization
 is_a: GO:0030834 {is_inferred="true"} ! regulation of actin filament depolymerization
 is_a: GO:1901881 {is_inferred="true"} ! positive regulation of protein depolymerization
+is_a: GO:1902905 {is_inferred="true"} ! positive regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0030837 ! negative regulation of actin filament polymerization
 is_a: GO:0030833 {is_inferred="true"} ! regulation of actin filament polymerization
 is_a: GO:0032272 {is_inferred="true"} ! negative regulation of protein polymerization
+is_a: GO:1902904 {is_inferred="true"} ! negative regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0030838 ! positive regulation of actin filament polymerization
 is_a: GO:0030833 {is_inferred="true"} ! regulation of actin filament polymerization
 is_a: GO:0032273 {is_inferred="true"} ! positive regulation of protein polymerization
+is_a: GO:1902905 {is_inferred="true"} ! positive regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0030839 ! regulation of intermediate filament polymerization
@@ -21176,11 +21190,13 @@
 id: GO:0031113 ! regulation of microtubule polymerization
 is_a: GO:0031110 {is_inferred="true"} ! regulation of microtubule polymerization or depolymerization
 is_a: GO:0032271 {is_inferred="true"} ! regulation of protein polymerization
+is_a: GO:1902903 {is_inferred="true"} ! regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0031114 ! regulation of microtubule depolymerization
 is_a: GO:0031110 {is_inferred="true"} ! regulation of microtubule polymerization or depolymerization
 is_a: GO:1901879 {is_inferred="true"} ! regulation of protein depolymerization
+is_a: GO:1902903 {is_inferred="true"} ! regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0031115 ! negative regulation of microtubule polymerization
@@ -21187,6 +21203,7 @@
 is_a: GO:0031111 {is_inferred="true"} ! negative regulation of microtubule polymerization or depolymerization
 is_a: GO:0031113 {is_inferred="true"} ! regulation of microtubule polymerization
 is_a: GO:0032272 {is_inferred="true"} ! negative regulation of protein polymerization
+is_a: GO:1902904 {is_inferred="true"} ! negative regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0031116 ! positive regulation of microtubule polymerization
@@ -21193,6 +21210,7 @@
 is_a: GO:0031112 {is_inferred="true"} ! positive regulation of microtubule polymerization or depolymerization
 is_a: GO:0031113 {is_inferred="true"} ! regulation of microtubule polymerization
 is_a: GO:0032273 {is_inferred="true"} ! positive regulation of protein polymerization
+is_a: GO:1902905 {is_inferred="true"} ! positive regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0031117 ! positive regulation of microtubule depolymerization
@@ -21199,8 +21217,13 @@
 is_a: GO:0031112 {is_inferred="true"} ! positive regulation of microtubule polymerization or depolymerization
 is_a: GO:0031114 {is_inferred="true"} ! regulation of microtubule depolymerization
 is_a: GO:1901881 {is_inferred="true"} ! positive regulation of protein depolymerization
+is_a: GO:1902905 {is_inferred="true"} ! positive regulation of supramolecular fiber organization
 
 [Term]
+id: GO:0031122 ! cytoplasmic microtubule organization
+is_a: GO:0097435 {is_inferred="true"} ! supramolecular fiber organization
+
+[Term]
 id: GO:0031135 ! negative regulation of conjugation
 is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:0046999 {is_inferred="true"} ! regulation of conjugation
@@ -22986,15 +23009,18 @@
 id: GO:0032231 ! regulation of actin filament bundle assembly
 is_a: GO:0032956 {is_inferred="true"} ! regulation of actin cytoskeleton organization
 is_a: GO:0044087 {is_inferred="true"} ! regulation of cellular component biogenesis
+is_a: GO:1902903 {is_inferred="true"} ! regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0032232 ! negative regulation of actin filament bundle assembly
 is_a: GO:0032231 {is_inferred="true"} ! regulation of actin filament bundle assembly
+is_a: GO:1902904 {is_inferred="true"} ! negative regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0032233 ! positive regulation of actin filament bundle assembly
 is_a: GO:0032231 {is_inferred="true"} ! regulation of actin filament bundle assembly
 is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
+is_a: GO:1902905 {is_inferred="true"} ! positive regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0032238 ! adenosine transport
@@ -35136,6 +35162,10 @@
 is_a: GO:0051493 {is_inferred="true"} ! regulation of cytoskeleton organization
 
 [Term]
+id: GO:0045109 ! intermediate filament organization
+is_a: GO:0097435 {is_inferred="true"} ! supramolecular fiber organization
+
+[Term]
 id: GO:0045113 ! regulation of integrin biosynthetic process
 is_a: GO:0010556 {is_inferred="true"} ! regulation of macromolecule biosynthetic process
 is_a: GO:1903729 {is_inferred="true"} ! regulation of plasma membrane organization
@@ -40448,6 +40478,10 @@
 is_a: GO:2001141 {is_inferred="true"} ! regulation of RNA biosynthetic process
 
 [Term]
+id: GO:0046785 ! microtubule polymerization
+is_a: GO:0097435 {is_inferred="true"} ! supramolecular fiber organization
+
+[Term]
 id: GO:0046807 ! viral scaffold assembly and maintenance
 is_a: GO:0006461 {is_inferred="true"} ! protein complex assembly
 
@@ -43172,10 +43206,12 @@
 [Term]
 id: GO:0051126 ! negative regulation of actin nucleation
 is_a: GO:0051125 {is_inferred="true"} ! regulation of actin nucleation
+is_a: GO:1902904 {is_inferred="true"} ! negative regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0051127 ! positive regulation of actin nucleation
 is_a: GO:0051125 {is_inferred="true"} ! regulation of actin nucleation
+is_a: GO:1902905 {is_inferred="true"} ! positive regulation of supramolecular fiber organization
 
 [Term]
 id: GO:0051133 ! regulation of NK T cell activation
@@ -75166,18 +75202,18 @@
 is_a: GO:2000785 {is_inferred="true"} ! regulation of autophagosome assembly
 
 [Term]
-id: GO:1902903 ! regulation of fibril organization
+id: GO:1902903 ! regulation of supramolecular fiber organization
 is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 
 [Term]
-id: GO:1902904 ! negative regulation of fibril organization
+id: GO:1902904 ! negative regulation of supramolecular fiber organization
 is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
-is_a: GO:1902903 {is_inferred="true"} ! regulation of fibril organization
+is_a: GO:1902903 {is_inferred="true"} ! regulation of supramolecular fiber organization
 
 [Term]
-id: GO:1902905 ! positive regulation of fibril organization
+id: GO:1902905 ! positive regulation of supramolecular fiber organization
 is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
-is_a: GO:1902903 {is_inferred="true"} ! regulation of fibril organization
+is_a: GO:1902903 {is_inferred="true"} ! regulation of supramolecular fiber organization
 
 [Term]
 id: GO:1902906 ! proteasome storage granule assembly
@@ -76138,6 +76174,7 @@
 
 [Term]
 id: GO:1903117 ! regulation of actin filament organization involved in cytokinetic actomyosin contractile ring assembly
+is_a: GO:1902903 {is_inferred="true"} ! regulation of supramolecular fiber organization
 is_a: GO:2000431 {is_inferred="true"} ! regulation of cytokinesis, actomyosin contractile ring assembly
 
 [Term]
@@ -77824,11 +77861,13 @@
 
 [Term]
 id: GO:1903481 ! negative regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly
+is_a: GO:1902904 {is_inferred="true"} ! negative regulation of supramolecular fiber organization
 is_a: GO:1903480 {is_inferred="true"} ! regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly
 is_a: GO:1903500 {is_inferred="true"} ! negative regulation of mitotic actomyosin contractile ring assembly
 
 [Term]
 id: GO:1903482 ! positive regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly
+is_a: GO:1902905 {is_inferred="true"} ! positive regulation of supramolecular fiber organization
 is_a: GO:1903480 {is_inferred="true"} ! regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly
 is_a: GO:1903501 {is_inferred="true"} ! positive regulation of mitotic actomyosin contractile ring assembly
 
@@ -80420,15 +80459,18 @@
 
 [Term]
 id: GO:1904026 ! regulation of collagen fibril organization
+is_a: GO:1902903 {is_inferred="true"} ! regulation of supramolecular fiber organization
 is_a: GO:1903053 {is_inferred="true"} ! regulation of extracellular matrix organization
 
 [Term]
 id: GO:1904027 ! negative regulation of collagen fibril organization
+is_a: GO:1902904 {is_inferred="true"} ! negative regulation of supramolecular fiber organization
 is_a: GO:1903054 {is_inferred="true"} ! negative regulation of extracellular matrix organization
 is_a: GO:1904026 {is_inferred="true"} ! regulation of collagen fibril organization
 
 [Term]
 id: GO:1904028 ! positive regulation of collagen fibril organization
+is_a: GO:1902905 {is_inferred="true"} ! positive regulation of supramolecular fiber organization
 is_a: GO:1903055 {is_inferred="true"} ! positive regulation of extracellular matrix organization
 is_a: GO:1904026 {is_inferred="true"} ! regulation of collagen fibril organization
 
@@ -87965,6 +88007,7 @@
 [Term]
 id: GO:1905590 ! fibronectin fibril organization
 is_a: GO:0030198 {is_inferred="true"} ! extracellular matrix organization
+is_a: GO:0097435 {is_inferred="true"} ! supramolecular fiber organization
 
 [Term]
 id: GO:1905591 ! regulation of optical nerve axon regeneration
------------------------------------------------------------------------
r37743 | dph | 2016-12-21 04:54:09 -0800 (Wed, 21 Dec 2016) | 2 lines

Merged extracellular fibril organization with fibril organization using Protege as part of GH12640.

changes in entailments

------------------------------------------------------------------------
r37741 | paola | 2016-12-21 03:39:09 -0800 (Wed, 21 Dec 2016) | 2 lines

GH NTR: Endosomal membrane tubulation #12583 - closed - see ticket for details

changes in entailments

------------------------------------------------------------------------
r37739 | paola | 2016-12-21 03:09:44 -0800 (Wed, 21 Dec 2016) | 2 lines

GH NTR: Endosomal membrane tubulation #12583 - work in progress - edited GO:0097320 ‘membrane tubulation’

changes in entailments

------------------------------------------------------------------------
r37735 | dph | 2016-12-20 12:20:43 -0800 (Tue, 20 Dec 2016) | 2 lines

Removed inconsistent relations and logical definitions from fibril organization and extracellular fibril organization terms. These terms will eventually be merged and renamed supramolecular fiber organization.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37736)
+++ go_inferences.obo	(working copy)
@@ -57967,10 +57967,6 @@
 is_a: GO:1905270 {is_inferred="true"} ! Meynert cell differentiation
 
 [Term]
-id: GO:0097435 ! fibril organization
-is_a: GO:0030198 {is_inferred="true"} ! extracellular matrix organization
-
-[Term]
 id: GO:0097444 ! spine apparatus
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
 is_a: GO:0044463 {is_inferred="true"} ! cell projection part
@@ -75171,17 +75167,17 @@
 
 [Term]
 id: GO:1902903 ! regulation of fibril organization
-is_a: GO:1903053 {is_inferred="true"} ! regulation of extracellular matrix organization
+is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 
 [Term]
 id: GO:1902904 ! negative regulation of fibril organization
+is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:1902903 {is_inferred="true"} ! regulation of fibril organization
-is_a: GO:1903054 {is_inferred="true"} ! negative regulation of extracellular matrix organization
 
 [Term]
 id: GO:1902905 ! positive regulation of fibril organization
+is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 is_a: GO:1902903 {is_inferred="true"} ! regulation of fibril organization
-is_a: GO:1903055 {is_inferred="true"} ! positive regulation of extracellular matrix organization
 
 [Term]
 id: GO:1902906 ! proteasome storage granule assembly
------------------------------------------------------------------------
r37733 | dph | 2016-12-20 11:46:35 -0800 (Tue, 20 Dec 2016) | 2 lines

GH12882-closed

changes in entailments

------------------------------------------------------------------------
r37731 | tberardi | 2016-12-20 11:17:43 -0800 (Tue, 20 Dec 2016) | 1 line

GH12766 Review MF term GO:0050827 'toxin receptor binding' - final bit of work, merging

changes in entailments

------------------------------------------------------------------------
r37729 | termgenie | 2016-12-20 10:46:49 -0800 (Tue, 20 Dec 2016) | 4 lines

TermGenie commit for user: NancyCampbell reviewed by ukemi

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37729)
+++ go_inferences.obo	(working copy)
@@ -88759,6 +88759,37 @@
 is_a: GO:0032403 {is_inferred="true"} ! protein complex binding
 
 [Term]
+id: GO:1905764 ! regulation of protection from non-homologous end joining at telomere
+is_a: GO:1904353 {is_inferred="true"} ! regulation of telomere capping
+is_a: GO:1904505 {is_inferred="true"} ! regulation of telomere maintenance in response to DNA damage
+
+[Term]
+id: GO:1905765 ! negative regulation of protection from non-homologous end joining at telomere
+is_a: GO:1904354 {is_inferred="true"} ! negative regulation of telomere capping
+is_a: GO:1904506 {is_inferred="true"} ! negative regulation of telomere maintenance in response to DNA damage
+is_a: GO:1905764 {is_inferred="true"} ! regulation of protection from non-homologous end joining at telomere
+
+[Term]
+id: GO:1905766 ! positive regulation of protection from non-homologous end joining at telomere
+is_a: GO:1904355 {is_inferred="true"} ! positive regulation of telomere capping
+is_a: GO:1904507 {is_inferred="true"} ! positive regulation of telomere maintenance in response to DNA damage
+is_a: GO:1905764 {is_inferred="true"} ! regulation of protection from non-homologous end joining at telomere
+
+[Term]
+id: GO:1905767 ! regulation of double-stranded telomeric DNA binding
+is_a: GO:1904742 {is_inferred="true"} ! regulation of telomeric DNA binding
+
+[Term]
+id: GO:1905768 ! negative regulation of double-stranded telomeric DNA binding
+is_a: GO:1904743 {is_inferred="true"} ! negative regulation of telomeric DNA binding
+is_a: GO:1905767 {is_inferred="true"} ! regulation of double-stranded telomeric DNA binding
+
+[Term]
+id: GO:1905769 ! positive regulation of double-stranded telomeric DNA binding
+is_a: GO:1904744 {is_inferred="true"} ! positive regulation of telomeric DNA binding
+is_a: GO:1905767 {is_inferred="true"} ! regulation of double-stranded telomeric DNA binding
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37726 | dph | 2016-12-20 09:38:50 -0800 (Tue, 20 Dec 2016) | 2 lines

Added namespace for new term.

changes in entailments

------------------------------------------------------------------------
r37723 | paola | 2016-12-20 08:16:55 -0800 (Tue, 20 Dec 2016) | 3 lines

GH NTR: "anatomical structure formation involved in reproduction (asexual and sexual) for conidium formation relationship #12745 - closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37723)
+++ go_inferences.obo	(working copy)
@@ -27564,6 +27564,14 @@
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
+id: GO:0034298 ! arthrospore formation
+is_a: GO:0048646 {is_inferred="true"} ! anatomical structure formation involved in morphogenesis
+
+[Term]
+id: GO:0034299 ! reproductive blastospore formation
+is_a: GO:0048646 {is_inferred="true"} ! anatomical structure formation involved in morphogenesis
+
+[Term]
 id: GO:0034304 ! actinomycete-type spore formation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 
@@ -55088,7 +55096,6 @@
 
 [Term]
 id: GO:0075306 ! regulation of conidium formation
-is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
 is_a: GO:0034305 {is_inferred="true"} ! regulation of asexual sporulation
 is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
 
------------------------------------------------------------------------
r37721 | dph | 2016-12-20 07:49:15 -0800 (Tue, 20 Dec 2016) | 2 lines

Added capable of part of relationship to GO:1990130.

changes in entailments

------------------------------------------------------------------------
r37719 | dph | 2016-12-20 06:55:28 -0800 (Tue, 20 Dec 2016) | 2 lines

GH12879-closed

changes in entailments

------------------------------------------------------------------------
r37712 | dph | 2016-12-20 05:25:25 -0800 (Tue, 20 Dec 2016) | 2 lines

GH12500-closed Added gluconate pathway synonym to GO:0061679

changes in entailments

------------------------------------------------------------------------
r37710 | davidos | 2016-12-19 23:37:25 -0800 (Mon, 19 Dec 2016) | 28 lines

### Fixed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37710)
+++ go_inferences.obo	(working copy)
@@ -76092,11 +76092,9 @@
 [Term]
 id: GO:1903108 ! regulation of transcription from mitochondrial promoter
 is_a: GO:0006355 {is_inferred="true"} ! regulation of transcription, DNA-templated
-is_a: GO:0010821 {is_inferred="true"} ! regulation of mitochondrion organization
 
 [Term]
 id: GO:1903109 ! positive regulation of transcription from mitochondrial promoter
-is_a: GO:0010822 {is_inferred="true"} ! positive regulation of mitochondrion organization
 is_a: GO:0045893 {is_inferred="true"} ! positive regulation of transcription, DNA-templated
 is_a: GO:1903108 {is_inferred="true"} ! regulation of transcription from mitochondrial promoter
 
@@ -89585,6 +89583,10 @@
 is_a: GO:0044440 {is_inferred="true"} ! endosomal part
 
 [Term]
+id: GO:1990755 ! mitotic spindle microtubule depolymerization
+is_a: GO:0007019 {is_inferred="true"} ! microtubule depolymerization
+
+[Term]
 id: GO:1990758 ! mitotic sister chromatid biorientation
 is_a: GO:0031134 {is_inferred="true"} ! sister chromatid biorientation
 
------------------------------------------------------------------------
r37706 | tberardi | 2016-12-19 15:43:26 -0800 (Mon, 19 Dec 2016) | 1 line

added xps for pos, neg reg of brood size terms

changes in entailments

------------------------------------------------------------------------
r37704 | tberardi | 2016-12-19 15:34:24 -0800 (Mon, 19 Dec 2016) | 1 line

GH12766 Review MF term GO:0050827 'toxin receptor binding' - closed

changes in entailments

------------------------------------------------------------------------
r37702 | tberardi | 2016-12-19 15:18:54 -0800 (Mon, 19 Dec 2016) | 1 line

GH12869 Regualtion term for GO:0060378 - closed

changes in entailments

------------------------------------------------------------------------
r37700 | dph | 2016-12-19 15:02:15 -0800 (Mon, 19 Dec 2016) | 2 lines

GH12875-closed

changes in entailments

------------------------------------------------------------------------
r37698 | dph | 2016-12-19 14:53:29 -0800 (Mon, 19 Dec 2016) | 2 lines

GH12874-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37698)
+++ go_inferences.obo	(working copy)
@@ -7866,7 +7866,6 @@
 [Term]
 id: GO:0007052 ! mitotic spindle organization
 is_a: GO:0007051 {is_inferred="true"} ! spindle organization
-is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
 id: GO:0007053 ! spindle assembly involved in male meiosis
@@ -46028,7 +46027,7 @@
 
 [Term]
 id: GO:0060236 ! regulation of mitotic spindle organization
-is_a: GO:0007346 {is_inferred="true"} ! regulation of mitotic cell cycle
+is_a: GO:0007088 {is_inferred="true"} ! regulation of mitotic nuclear division
 is_a: GO:0090224 {is_inferred="true"} ! regulation of spindle organization
 
 [Term]
@@ -49072,12 +49071,10 @@
 [Term]
 id: GO:0061804 ! mitotic spindle elongation during mitotic prophase
 is_a: GO:0007052 {is_inferred="true"} ! mitotic spindle organization
-is_a: GO:1902850 {is_inferred="true"} ! microtubule cytoskeleton organization involved in mitosis
 
 [Term]
 id: GO:0061805 ! mitotic spindle elongation during mitotic anaphase
 is_a: GO:0007052 {is_inferred="true"} ! mitotic spindle organization
-is_a: GO:1902850 {is_inferred="true"} ! microtubule cytoskeleton organization involved in mitosis
 
 [Term]
 id: GO:0061816 ! proteaphagy
@@ -56812,7 +56809,6 @@
 id: GO:0090307 ! mitotic spindle assembly
 is_a: GO:0007052 {is_inferred="true"} ! mitotic spindle organization
 is_a: GO:0051225 {is_inferred="true"} ! spindle assembly
-is_a: GO:1902850 {is_inferred="true"} ! microtubule cytoskeleton organization involved in mitosis
 
 [Term]
 id: GO:0090308 ! regulation of methylation-dependent chromatin silencing
@@ -69164,7 +69160,6 @@
 
 [Term]
 id: GO:1901673 ! regulation of mitotic spindle assembly
-is_a: GO:0007088 {is_inferred="true"} ! regulation of mitotic nuclear division
 is_a: GO:0060236 {is_inferred="true"} ! regulation of mitotic spindle organization
 is_a: GO:0090169 {is_inferred="true"} ! regulation of spindle assembly
 
@@ -83621,9 +83616,8 @@
 
 [Term]
 id: GO:1904687 ! positive regulation of mitotic spindle disassembly
-is_a: GO:0045931 {is_inferred="true"} ! positive regulation of mitotic cell cycle
+is_a: GO:0045840 {is_inferred="true"} ! positive regulation of mitotic nuclear division
 is_a: GO:0051495 {is_inferred="true"} ! positive regulation of cytoskeleton organization
-is_a: GO:0090068 {is_inferred="true"} ! positive regulation of cell cycle process
 is_a: GO:1904686 {is_inferred="true"} ! regulation of mitotic spindle disassembly
 
 [Term]
@@ -89651,7 +89645,7 @@
 
 [Term]
 id: GO:1990810 ! microtubule anchoring at mitotic spindle pole body
-is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
+is_a: GO:1902850 {is_inferred="true"} ! microtubule cytoskeleton organization involved in mitosis
 
 [Term]
 id: GO:1990818 ! L-arginine transmembrane export from vacuole
------------------------------------------------------------------------
r37695 | dph | 2016-12-19 14:39:17 -0800 (Mon, 19 Dec 2016) | 2 lines

GH12868-closed

changes in entailments

------------------------------------------------------------------------
r37693 | paola | 2016-12-19 09:56:42 -0800 (Mon, 19 Dec 2016) | 2 lines

GH request taxon constraint for milk ejection #11995 - work in progress - see ticket for details

changes in entailments

------------------------------------------------------------------------
r37687 | paola | 2016-12-19 02:33:07 -0800 (Mon, 19 Dec 2016) | 3 lines

GH GO:0003729 mRNA binding is currently child of poly(A) RNA binding #11022 - work in progress - fixed typos in def and comment of ‘poly(A) RNA binding’

changes in entailments

------------------------------------------------------------------------
r37685 | paola | 2016-12-18 23:45:52 -0800 (Sun, 18 Dec 2016) | 2 lines

GH Incorrect is_a relationship "photoreceptor cell cilium" GO:0097733 #12871 - closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37685)
+++ go_inferences.obo	(working copy)
@@ -2442,30 +2442,10 @@
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
-id: GO:0002554 ! serotonin secretion by platelet
-is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
-
-[Term]
-id: GO:0002555 ! histamine secretion by platelet
-is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
-
-[Term]
-id: GO:0002556 ! serotonin secretion by basophil
-is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
-
-[Term]
-id: GO:0002557 ! histamine secretion by basophil
-is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
-
-[Term]
 id: GO:0002575 ! basophil chemotaxis
 is_a: GO:0071621 {is_inferred="true"} ! granulocyte chemotaxis
 
 [Term]
-id: GO:0002576 ! platelet degranulation
-is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
-
-[Term]
 id: GO:0002577 ! regulation of antigen processing and presentation
 is_a: GO:0002682 {is_inferred="true"} ! regulation of immune system process
 
@@ -8081,6 +8061,10 @@
 is_a: GO:0046330 {is_inferred="true"} ! positive regulation of JNK cascade
 
 [Term]
+id: GO:0007267 ! cell-cell signaling
+is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
+
+[Term]
 id: GO:0007268 ! chemical synaptic transmission
 is_a: GO:0098916 {is_inferred="true"} ! anterograde trans-synaptic signaling
 
@@ -8270,10 +8254,6 @@
 is_a: GO:0060429 {is_inferred="true"} ! epithelium development
 
 [Term]
-id: GO:0007488 ! histoblast morphogenesis
-is_a: GO:0000902 {is_inferred="true"} ! cell morphogenesis
-
-[Term]
 id: GO:0007503 ! fat body development
 is_a: GO:0060612 {is_inferred="true"} ! adipose tissue development
 
@@ -8304,7 +8284,7 @@
 
 [Term]
 id: GO:0007543 ! sex determination, somatic-gonadal interaction
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0022414 {is_inferred="true"} ! reproductive process
 
 [Term]
 id: GO:0007553 ! regulation of ecdysteroid metabolic process
@@ -10585,7 +10565,7 @@
 
 [Term]
 id: GO:0009875 ! pollen-pistil interaction
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0022414 {is_inferred="true"} ! reproductive process
 
 [Term]
 id: GO:0009876 ! pollen adhesion
@@ -19294,6 +19274,10 @@
 is_a: GO:0048870 {is_inferred="true"} ! cell motility
 
 [Term]
+id: GO:0021807 ! motogenic signaling initiating cell movement in cerebral cortex
+is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
+
+[Term]
 id: GO:0021814 ! cell motility involved in cerebral cortex radial glia guided migration
 is_a: GO:0048870 {is_inferred="true"} ! cell motility
 
@@ -19322,6 +19306,14 @@
 is_a: GO:0050919 {is_inferred="true"} ! negative chemotaxis
 
 [Term]
+id: GO:0021837 ! motogenic signaling involved in postnatal olfactory bulb interneuron migration
+is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
+
+[Term]
+id: GO:0021838 ! motogenic signaling involved in interneuron migration from the subpallium to the cortex
+is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
+
+[Term]
 id: GO:0021841 ! chemoattraction involved in interneuron migration from the subpallium to the cortex
 is_a: GO:0050918 {is_inferred="true"} ! positive chemotaxis
 
@@ -21259,7 +21251,6 @@
 [Term]
 id: GO:0031152 ! aggregation involved in sorocarp development
 is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0031155 ! regulation of reproductive fruiting body development
@@ -26139,11 +26130,11 @@
 
 [Term]
 id: GO:0033370 ! maintenance of protein location in mast cell secretory granule
-is_a: GO:0032507 {is_inferred="true"} ! maintenance of protein location in cell
+is_a: GO:0051651 {is_inferred="true"} ! maintenance of location in cell
 
 [Term]
 id: GO:0033377 ! maintenance of protein location in T cell secretory granule
-is_a: GO:0032507 {is_inferred="true"} ! maintenance of protein location in cell
+is_a: GO:0051651 {is_inferred="true"} ! maintenance of location in cell
 
 [Term]
 id: GO:0033383 ! geranyl diphosphate metabolic process
@@ -28764,6 +28755,10 @@
 is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
 
 [Term]
+id: GO:0035426 ! extracellular matrix-cell signaling
+is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
+
+[Term]
 id: GO:0035428 ! hexose transmembrane transport
 is_a: GO:0008645 {is_inferred="true"} ! hexose transport
 is_a: GO:0034219 {is_inferred="true"} ! carbohydrate transmembrane transport
@@ -30989,10 +30984,6 @@
 is_a: GO:0022618 {is_inferred="true"} ! ribonucleoprotein complex assembly
 
 [Term]
-id: GO:0042262 ! DNA protection
-is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
-
-[Term]
 id: GO:0042269 ! regulation of natural killer cell mediated cytotoxicity
 is_a: GO:0001910 {is_inferred="true"} ! regulation of leukocyte mediated cytotoxicity
 is_a: GO:0002715 {is_inferred="true"} ! regulation of natural killer cell mediated immunity
@@ -33142,13 +33133,8 @@
 is_a: GO:0007043 {is_inferred="true"} ! cell-cell junction assembly
 
 [Term]
-id: GO:0043299 ! leukocyte degranulation
-is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
-
-[Term]
 id: GO:0043300 ! regulation of leukocyte degranulation
 is_a: GO:0002697 {is_inferred="true"} ! regulation of immune effector process
-is_a: GO:0060341 {is_inferred="true"} ! regulation of cellular localization
 is_a: GO:1903305 {is_inferred="true"} ! regulation of regulated secretory pathway
 
 [Term]
@@ -40020,7 +40006,6 @@
 [Term]
 id: GO:0046595 ! establishment of pole plasm mRNA localization
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
 is_a: GO:1902578 {is_inferred="true"} ! single-organism localization
 
 [Term]
@@ -50142,10 +50127,6 @@
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
 [Term]
-id: GO:0070560 ! protein secretion by platelet
-is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
-
-[Term]
 id: GO:0070562 ! regulation of vitamin D receptor signaling pathway
 is_a: GO:0009966 {is_inferred="true"} ! regulation of signal transduction
 is_a: GO:0032107 {is_inferred="true"} ! regulation of response to nutrient levels
@@ -60183,13 +60164,8 @@
 is_a: GO:0098576 {is_inferred="true"} ! lumenal side of membrane
 
 [Term]
-id: GO:0099622 ! cardiac muscle cell membrane repolarization
-is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
-
-[Term]
 id: GO:0099623 ! regulation of cardiac muscle cell membrane repolarization
 is_a: GO:0060306 {is_inferred="true"} ! regulation of membrane repolarization
-is_a: GO:0060341 {is_inferred="true"} ! regulation of cellular localization
 
 [Term]
 id: GO:0099624 ! atrial cardiac muscle cell membrane repolarization
@@ -68939,10 +68915,6 @@
 is_a: GO:0022857 {is_inferred="true"} ! transmembrane transporter activity
 
 [Term]
-id: GO:1901619 ! tRNA methylation in response to nitrogen starvation
-is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
-
-[Term]
 id: GO:1901620 ! regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
 is_a: GO:0008589 {is_inferred="true"} ! regulation of smoothened signaling pathway
 is_a: GO:0045995 {is_inferred="true"} ! regulation of embryonic development
------------------------------------------------------------------------
r37639 | dph | 2016-12-15 17:03:40 -0800 (Thu, 15 Dec 2016) | 2 lines

Added mouse slim to the ontology.

changes in entailments

------------------------------------------------------------------------
r37637 | termgenie | 2016-12-15 15:16:07 -0800 (Thu, 15 Dec 2016) | 3 lines

TermGenie commit for user: mah11 reviewed by tberardini

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37637)
+++ go_inferences.obo	(working copy)
@@ -88780,6 +88780,14 @@
 is_a: GO:0044877 {is_inferred="true"} ! macromolecular complex binding
 
 [Term]
+id: GO:1905762 ! CCR4-NOT complex binding
+is_a: GO:0032403 {is_inferred="true"} ! protein complex binding
+
+[Term]
+id: GO:1905763 ! MTREC complex binding
+is_a: GO:0032403 {is_inferred="true"} ! protein complex binding
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37623 | dph | 2016-12-14 08:21:53 -0800 (Wed, 14 Dec 2016) | 2 lines

GH11048-closed

changes in entailments

------------------------------------------------------------------------
r37621 | termgenie | 2016-12-14 07:15:38 -0800 (Wed, 14 Dec 2016) | 2 lines

TermGenie commit for user: ukemi reviewed by ukemi

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37621)
+++ go_inferences.obo	(working copy)
@@ -88776,6 +88776,10 @@
 is_a: GO:1990752 {is_inferred="true"} ! microtubule end
 
 [Term]
+id: GO:1905761 ! SCF ubiquitin ligase complex binding
+is_a: GO:0044877 {is_inferred="true"} ! macromolecular complex binding
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37619 | dph | 2016-12-14 06:52:57 -0800 (Wed, 14 Dec 2016) | 2 lines

GH12863-closed

changes in entailments

------------------------------------------------------------------------
r37611 | termgenie | 2016-12-13 18:05:29 -0800 (Tue, 13 Dec 2016) | 4 lines

TermGenie commit for user: ValWood reviewed by tberardini

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37612)
+++ go_inferences.obo	(working copy)
@@ -75114,6 +75114,7 @@
 [Term]
 id: GO:1902888 ! protein localization to astral microtubule
 is_a: GO:1902889 {is_inferred="true"} ! protein localization to spindle microtubule
+is_a: GO:1905755 {is_inferred="true"} ! protein localization to cytoplasmic microtubule
 
 [Term]
 id: GO:1902889 ! protein localization to spindle microtubule
@@ -82844,6 +82845,7 @@
 [Term]
 id: GO:1904518 ! protein localization to cytoplasmic microtubule plus-end
 is_a: GO:1904825 {is_inferred="true"} ! protein localization to microtubule plus-end
+is_a: GO:1905755 {is_inferred="true"} ! protein localization to cytoplasmic microtubule
 
 [Term]
 id: GO:1904519 ! protein localization to microtubule minus-end
@@ -88744,6 +88746,28 @@
 is_a: GO:1905752 {is_inferred="true"} ! regulation of argininosuccinate synthase activity
 
 [Term]
+id: GO:1905754 ! ascospore-type prospore nucleus
+is_a: GO:0005634 {is_inferred="true"} ! nucleus
+
+[Term]
+id: GO:1905755 ! protein localization to cytoplasmic microtubule
+is_a: GO:0035372 {is_inferred="true"} ! protein localization to microtubule
+
+[Term]
+id: GO:1905756 ! regulation of primary cell septum biogenesis
+is_a: GO:0032955 {is_inferred="true"} ! regulation of barrier septum assembly
+
+[Term]
+id: GO:1905757 ! negative regulation of primary cell septum biogenesis
+is_a: GO:0010974 {is_inferred="true"} ! negative regulation of barrier septum assembly
+is_a: GO:1905756 {is_inferred="true"} ! regulation of primary cell septum biogenesis
+
+[Term]
+id: GO:1905758 ! positive regulation of primary cell septum biogenesis
+is_a: GO:0010973 {is_inferred="true"} ! positive regulation of barrier septum assembly
+is_a: GO:1905756 {is_inferred="true"} ! regulation of primary cell septum biogenesis
+
+[Term]
 id: GO:1905759 ! post-anaphase array microtubule
 is_a: GO:0005874 {is_inferred="true"} ! microtubule
 
------------------------------------------------------------------------
r37607 | dph | 2016-12-13 13:08:47 -0800 (Tue, 13 Dec 2016) | 2 lines

GH12860-closed

changes in entailments

------------------------------------------------------------------------
r37597 | davidos | 2016-12-13 05:35:26 -0800 (Tue, 13 Dec 2016) | 1 line

Fixed EC pair

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37604)
+++ go_inferences.obo	(working copy)
@@ -96200,6 +96200,14 @@
 is_a: GOCHE:26155 {is_inferred="true"} ! substance with plant growth regulator biological role
 
 [Term]
+id: GOCHE:50113 ! substance with androgen hormone role
+is_a: GOCHE:24621 {is_inferred="true"} ! substance with hormone biological role
+
+[Term]
+id: GOCHE:50114 ! substance with estrogen hormone role
+is_a: GOCHE:24621 {is_inferred="true"} ! substance with hormone biological role
+
+[Term]
 id: GOCHE:51086 ! substance with chemical property
 is_a: CHEBI:24431 {is_inferred="true"} ! chemical entity
 
------------------------------------------------------------------------
r37597 | davidos | 2016-12-13 05:35:26 -0800 (Tue, 13 Dec 2016) | 1 line

Fixed EC pair

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37597)
+++ go_inferences.obo	(working copy)
@@ -840,6 +840,10 @@
 is_a: GO:0098610 {is_inferred="true"} ! adhesion between unicellular organisms
 
 [Term]
+id: GO:0000775 ! chromosome, centromeric region
+is_a: GO:0098687 {is_inferred="true"} ! chromosomal region
+
+[Term]
 id: GO:0000777 ! condensed chromosome kinetochore
 is_a: GO:0000776 {is_inferred="true"} ! kinetochore
 
@@ -858,6 +862,10 @@
 is_a: GO:0044454 {is_inferred="true"} ! nuclear chromosome part
 
 [Term]
+id: GO:0000781 ! chromosome, telomeric region
+is_a: GO:0098687 {is_inferred="true"} ! chromosomal region
+
+[Term]
 id: GO:0000783 ! nuclear telomere cap complex
 is_a: GO:0000782 {is_inferred="true"} ! telomere cap complex
 is_a: GO:0044454 {is_inferred="true"} ! nuclear chromosome part
@@ -4149,6 +4157,14 @@
 is_a: GO:0090500 {is_inferred="true"} ! endocardial cushion to mesenchymal transition
 
 [Term]
+id: GO:0003228 ! atrial cardiac muscle tissue development
+is_a: GO:0048856 {is_inferred="true"} ! anatomical structure development
+
+[Term]
+id: GO:0003229 ! ventricular cardiac muscle tissue development
+is_a: GO:0048738 {is_inferred="true"} ! cardiac muscle tissue development
+
+[Term]
 id: GO:0003245 ! cardiac muscle tissue growth involved in heart morphogenesis
 is_a: GO:0003241 {is_inferred="true"} ! growth involved in heart morphogenesis
 is_a: GO:0055017 {is_inferred="true"} ! cardiac muscle tissue growth
@@ -4356,6 +4372,10 @@
 is_a: GO:0045446 {is_inferred="true"} ! endothelial cell differentiation
 
 [Term]
+id: GO:0003350 ! pulmonary myocardium development
+is_a: GO:0014706 {is_inferred="true"} ! striated muscle tissue development
+
+[Term]
 id: GO:0003352 ! regulation of cilium movement
 is_a: GO:0060632 {is_inferred="true"} ! regulation of microtubule-based movement
 
@@ -4649,6 +4669,10 @@
 is_a: GO:0099106 {is_inferred="true"} ! ion channel regulator activity
 
 [Term]
+id: GO:0005260 ! channel-conductance-controlling ATPase activity
+is_a: GO:0043225 {is_inferred="true"} ! ATPase-coupled anion transmembrane transporter activity
+
+[Term]
 id: GO:0005274 ! allantoin uptake transmembrane transporter activity
 is_a: GO:0015563 {is_inferred="true"} ! uptake transmembrane transporter activity
 is_a: GO:0042887 {is_inferred="true"} ! amide transmembrane transporter activity
@@ -4962,10 +4986,6 @@
 is_a: GO:0098651 {is_inferred="true"} ! basement membrane collagen trimer
 
 [Term]
-id: GO:0005589 ! collagen type VI trimer
-is_a: GO:0044420 {is_inferred="true"} ! extracellular matrix component
-
-[Term]
 id: GO:0005591 ! collagen type VIII trimer
 is_a: GO:0030935 {is_inferred="true"} ! sheet-forming collagen trimer
 is_a: GO:0098651 {is_inferred="true"} ! basement membrane collagen trimer
@@ -8263,6 +8283,10 @@
 is_a: GO:0060485 {is_inferred="true"} ! mesenchyme development
 
 [Term]
+id: GO:0007519 ! skeletal muscle tissue development
+is_a: GO:0014706 {is_inferred="true"} ! striated muscle tissue development
+
+[Term]
 id: GO:0007528 ! neuromuscular junction development
 is_a: GO:0050808 {is_inferred="true"} ! synapse organization
 
@@ -8642,6 +8666,10 @@
 is_a: GO:0019829 {is_inferred="true"} ! cation-transporting ATPase activity
 
 [Term]
+id: GO:0008555 ! chloride-transporting ATPase activity
+is_a: GO:0043225 {is_inferred="true"} ! ATPase-coupled anion transmembrane transporter activity
+
+[Term]
 id: GO:0008556 ! potassium-transporting ATPase activity
 is_a: GO:0019829 {is_inferred="true"} ! cation-transporting ATPase activity
 
@@ -13554,17 +13582,17 @@
 
 [Term]
 id: GO:0014708 ! regulation of somitomeric trunk muscle development
-is_a: GO:0048641 {is_inferred="true"} ! regulation of skeletal muscle tissue development
+is_a: GO:0048634 {is_inferred="true"} ! regulation of muscle organ development
 
 [Term]
 id: GO:0014709 ! positive regulation of somitomeric trunk muscle development
 is_a: GO:0014708 {is_inferred="true"} ! regulation of somitomeric trunk muscle development
-is_a: GO:0048643 {is_inferred="true"} ! positive regulation of skeletal muscle tissue development
+is_a: GO:0048636 {is_inferred="true"} ! positive regulation of muscle organ development
 
 [Term]
 id: GO:0014710 ! negative regulation of somitomeric trunk muscle development
 is_a: GO:0014708 {is_inferred="true"} ! regulation of somitomeric trunk muscle development
-is_a: GO:0048642 {is_inferred="true"} ! negative regulation of skeletal muscle tissue development
+is_a: GO:0048635 {is_inferred="true"} ! negative regulation of muscle organ development
 
 [Term]
 id: GO:0014711 ! regulation of branchiomeric skeletal muscle development
@@ -14424,6 +14452,10 @@
 is_a: GO:0015563 {is_inferred="true"} ! uptake transmembrane transporter activity
 
 [Term]
+id: GO:0015411 ! taurine-transporting ATPase activity
+is_a: GO:0043225 {is_inferred="true"} ! ATPase-coupled anion transmembrane transporter activity
+
+[Term]
 id: GO:0015413 ! nickel-transporting ATPase activity
 is_a: GO:0019829 {is_inferred="true"} ! cation-transporting ATPase activity
 is_a: GO:0072509 {is_inferred="true"} ! divalent inorganic cation transmembrane transporter activity
@@ -14444,6 +14476,18 @@
 is_a: GO:0090482 {is_inferred="true"} ! vitamin transmembrane transporter activity
 
 [Term]
+id: GO:0015424 ! amino acid-transporting ATPase activity
+is_a: GO:0043225 {is_inferred="true"} ! ATPase-coupled anion transmembrane transporter activity
+
+[Term]
+id: GO:0015430 ! glycerol-3-phosphate-transporting ATPase activity
+is_a: GO:0043225 {is_inferred="true"} ! ATPase-coupled anion transmembrane transporter activity
+
+[Term]
+id: GO:0015432 ! bile acid-exporting ATPase activity
+is_a: GO:0043225 {is_inferred="true"} ! ATPase-coupled anion transmembrane transporter activity
+
+[Term]
 id: GO:0015444 ! magnesium-importing ATPase activity
 is_a: GO:0019829 {is_inferred="true"} ! cation-transporting ATPase activity
 
@@ -14644,6 +14688,10 @@
 is_a: GO:0015101 {is_inferred="true"} ! organic cation transmembrane transporter activity
 
 [Term]
+id: GO:0015610 ! glycerol phosphate-importing ATPase activity
+is_a: GO:0043225 {is_inferred="true"} ! ATPase-coupled anion transmembrane transporter activity
+
+[Term]
 id: GO:0015619 ! thiamine pyrophosphate-transporting ATPase activity
 is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:0015101 {is_inferred="true"} ! organic cation transmembrane transporter activity
@@ -15872,6 +15920,10 @@
 is_a: GO:1902600 {is_inferred="true"} ! hydrogen ion transmembrane transport
 
 [Term]
+id: GO:0015991 ! ATP hydrolysis coupled proton transport
+is_a: GO:0099132 {is_inferred="true"} ! ATP hydrolysis coupled cation transmembrane transport
+
+[Term]
 id: GO:0015992 ! proton transport
 is_a: GO:0006818 {is_inferred="true"} ! hydrogen transport
 is_a: GO:0015672 {is_inferred="true"} ! monovalent inorganic cation transport
@@ -25830,6 +25882,10 @@
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 
 [Term]
+id: GO:0033284 ! carboxylic acid-transporting ATPase activity
+is_a: GO:0043225 {is_inferred="true"} ! ATPase-coupled anion transmembrane transporter activity
+
+[Term]
 id: GO:0033287 ! hydroxyectoine transmembrane transporter activity
 is_a: GO:0015665 {is_inferred="true"} ! alcohol transmembrane transporter activity
 
@@ -27805,6 +27861,14 @@
 is_a: GO:0033365 {is_inferred="true"} ! protein localization to organelle
 
 [Term]
+id: GO:0034506 ! chromosome, centromeric core domain
+is_a: GO:0098687 {is_inferred="true"} ! chromosomal region
+
+[Term]
+id: GO:0034507 ! chromosome, centromeric outer repeat region
+is_a: GO:0098687 {is_inferred="true"} ! chromosomal region
+
+[Term]
 id: GO:0034516 ! response to vitamin B6
 is_a: GO:0010243 {is_inferred="true"} ! response to organonitrogen compound
 is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
@@ -40673,6 +40737,10 @@
 is_a: GO:1902224 {is_inferred="true"} ! ketone body metabolic process
 
 [Term]
+id: GO:0046962 ! sodium-transporting ATPase activity, rotational mechanism
+is_a: GO:0019829 {is_inferred="true"} ! cation-transporting ATPase activity
+
+[Term]
 id: GO:0046963 ! 3'-phosphoadenosine 5'-phosphosulfate transport
 is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015858 {is_inferred="true"} ! nucleoside transport
@@ -49012,6 +49080,11 @@
 is_a: GO:0005254 {is_inferred="true"} ! chloride channel activity
 
 [Term]
+id: GO:0061800 ! fibronectin fibril
+is_a: GO:0044420 {is_inferred="true"} ! extracellular matrix component
+is_a: GO:0099512 {is_inferred="true"} ! supramolecular fiber
+
+[Term]
 id: GO:0061804 ! mitotic spindle elongation during mitotic prophase
 is_a: GO:0007052 {is_inferred="true"} ! mitotic spindle organization
 is_a: GO:1902850 {is_inferred="true"} ! microtubule cytoskeleton organization involved in mitosis
@@ -57365,6 +57438,10 @@
 is_a: GO:0008033 {is_inferred="true"} ! tRNA processing
 
 [Term]
+id: GO:0090662 ! ATP hydrolysis coupled transmembrane transport
+is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
+
+[Term]
 id: GO:0090688 ! cleavage furrow rim
 is_a: GO:0032155 {is_inferred="true"} ! cell division site part
 
@@ -57489,6 +57566,10 @@
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
+id: GO:0097084 ! vascular smooth muscle cell development
+is_a: GO:0055001 {is_inferred="true"} ! muscle cell development
+
+[Term]
 id: GO:0097089 ! methyl-branched fatty acid metabolic process
 is_a: GO:0006631 {is_inferred="true"} ! fatty acid metabolic process
 
@@ -58393,6 +58474,18 @@
 is_a: GO:0098632 {is_inferred="true"} ! protein binding involved in cell-cell adhesion
 
 [Term]
+id: GO:0098643 ! banded collagen fibril
+is_a: GO:0099512 {is_inferred="true"} ! supramolecular fiber
+
+[Term]
+id: GO:0098645 ! collagen network
+is_a: GO:0099081 {is_inferred="true"} ! supramolecular polymer
+
+[Term]
+id: GO:0098647 ! collagen beaded filament
+is_a: GO:0099512 {is_inferred="true"} ! supramolecular fiber
+
+[Term]
 id: GO:0098649 ! response to peptidyl-dipeptidase A inhibitor
 is_a: GO:0042493 {is_inferred="true"} ! response to drug
 
@@ -59801,6 +59894,21 @@
 is_a: GO:0044420 {is_inferred="true"} ! extracellular matrix component
 
 [Term]
+id: GO:0099131 ! ATP hydrolysis coupled ion transmembrane transport
+is_a: GO:0090662 {is_inferred="true"} ! ATP hydrolysis coupled transmembrane transport
+is_a: GO:0098660 {is_inferred="true"} ! inorganic ion transmembrane transport
+
+[Term]
+id: GO:0099132 ! ATP hydrolysis coupled cation transmembrane transport
+is_a: GO:0098662 {is_inferred="true"} ! inorganic cation transmembrane transport
+is_a: GO:0099131 {is_inferred="true"} ! ATP hydrolysis coupled ion transmembrane transport
+
+[Term]
+id: GO:0099133 ! ATP hydrolysis coupled anion transmembrane transport
+is_a: GO:0098661 {is_inferred="true"} ! inorganic anion transmembrane transport
+is_a: GO:0099131 {is_inferred="true"} ! ATP hydrolysis coupled ion transmembrane transport
+
+[Term]
 id: GO:0099400 ! caveola neck
 is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
 
@@ -67001,7 +67109,7 @@
 
 [Term]
 id: GO:1901238 ! ATPase-coupled tungstate transmembrane transporter activity
-is_a: GO:0042626 {is_inferred="true"} ! ATPase activity, coupled to transmembrane movement of substances
+is_a: GO:0043225 {is_inferred="true"} ! ATPase-coupled anion transmembrane transporter activity
 is_a: GO:1901237 {is_inferred="true"} ! tungstate transmembrane transporter activity
 
 [Term]
@@ -67023,6 +67131,7 @@
 [Term]
 id: GO:1901243 ! ATPase-coupled methionine transmembrane transporter activity
 is_a: GO:0019829 {is_inferred="true"} ! cation-transporting ATPase activity
+is_a: GO:0043225 {is_inferred="true"} ! ATPase-coupled anion transmembrane transporter activity
 is_a: GO:0043865 {is_inferred="true"} ! methionine transmembrane transporter activity
 
 [Term]
------------------------------------------------------------------------
r37587 | termgenie | 2016-12-12 11:42:20 -0800 (Mon, 12 Dec 2016) | 2 lines

TermGenie commit for user: dosumis reviewed by dosumis

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37587)
+++ go_inferences.obo	(working copy)
@@ -88639,6 +88639,10 @@
 is_a: GO:0005874 {is_inferred="true"} ! microtubule
 
 [Term]
+id: GO:1905760 ! post-anaphase array microtubule end
+is_a: GO:1990752 {is_inferred="true"} ! microtubule end
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37585 | termgenie | 2016-12-12 10:39:01 -0800 (Mon, 12 Dec 2016) | 2 lines

TermGenie commit for user: dosumis reviewed by dosumis

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37585)
+++ go_inferences.obo	(working copy)
@@ -88635,6 +88635,10 @@
 is_a: GO:1905752 {is_inferred="true"} ! regulation of argininosuccinate synthase activity
 
 [Term]
+id: GO:1905759 ! post-anaphase array microtubule
+is_a: GO:0005874 {is_inferred="true"} ! microtubule
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37575 | termgenie | 2016-12-12 03:51:32 -0800 (Mon, 12 Dec 2016) | 3 lines

TermGenie commit for user: dosumis reviewed by dosumis

changes in entailments

------------------------------------------------------------------------
r37575 | termgenie | 2016-12-12 03:51:32 -0800 (Mon, 12 Dec 2016) | 3 lines

TermGenie commit for user: dosumis reviewed by dosumis

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37575)
+++ go_inferences.obo	(working copy)
@@ -88626,6 +88626,15 @@
 is_a: GO:1905749 {is_inferred="true"} ! regulation of endosome to plasma membrane protein transport
 
 [Term]
+id: GO:1905752 ! regulation of argininosuccinate synthase activity
+is_a: GO:0051340 {is_inferred="true"} ! regulation of ligase activity
+
+[Term]
+id: GO:1905753 ! positive regulation of argininosuccinate synthase activity
+is_a: GO:0051351 {is_inferred="true"} ! positive regulation of ligase activity
+is_a: GO:1905752 {is_inferred="true"} ! regulation of argininosuccinate synthase activity
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37573 | paola | 2016-12-12 01:44:48 -0800 (Mon, 12 Dec 2016) | 2 lines

Removed extra whitespace in label of GO:0060854

changes in entailments

------------------------------------------------------------------------
r37557 | termgenie | 2016-12-09 15:39:29 -0800 (Fri, 09 Dec 2016) | 4 lines

TermGenie commit for user: pgarmiri reviewed by ukemi

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37557)
+++ go_inferences.obo	(working copy)
@@ -88598,6 +88598,34 @@
 is_a: GO:1905744 {is_inferred="true"} ! regulation of mRNA cis splicing, via spliceosome
 
 [Term]
+id: GO:1905747 ! negative regulation of saliva secretion
+is_a: GO:0046877 {is_inferred="true"} ! regulation of saliva secretion
+is_a: GO:0051048 {is_inferred="true"} ! negative regulation of secretion
+is_a: GO:0060457 {is_inferred="true"} ! negative regulation of digestive system process
+
+[Term]
+id: GO:1905748 ! hard palate morphogenesis
+is_a: GO:0009653 {is_inferred="true"} ! anatomical structure morphogenesis
+
+[Term]
+id: GO:1905749 ! regulation of endosome to plasma membrane protein transport
+is_a: GO:0051223 {is_inferred="true"} ! regulation of protein transport
+is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
+is_a: GO:0090003 {is_inferred="true"} ! regulation of establishment of protein localization to plasma membrane
+
+[Term]
+id: GO:1905750 ! negative regulation of endosome to plasma membrane protein transport
+is_a: GO:0051224 {is_inferred="true"} ! negative regulation of protein transport
+is_a: GO:0090005 {is_inferred="true"} ! negative regulation of establishment of protein localization to plasma membrane
+is_a: GO:1905749 {is_inferred="true"} ! regulation of endosome to plasma membrane protein transport
+
+[Term]
+id: GO:1905751 ! positive regulation of endosome to plasma membrane protein transport
+is_a: GO:0051222 {is_inferred="true"} ! positive regulation of protein transport
+is_a: GO:0090004 {is_inferred="true"} ! positive regulation of establishment of protein localization to plasma membrane
+is_a: GO:1905749 {is_inferred="true"} ! regulation of endosome to plasma membrane protein transport
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37552 | davidos | 2016-12-09 10:09:41 -0800 (Fri, 09 Dec 2016) | 1 line

Fixed consistency issues.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37552)
+++ go_inferences.obo	(working copy)
@@ -3235,7 +3235,6 @@
 is_a: GO:0002831 {is_inferred="true"} ! regulation of response to biotic stimulus
 is_a: GO:0002920 {is_inferred="true"} ! regulation of humoral immune response
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 
 [Term]
 id: GO:0002760 ! positive regulation of antimicrobial humoral response
@@ -3243,7 +3242,6 @@
 is_a: GO:0002833 {is_inferred="true"} ! positive regulation of response to biotic stimulus
 is_a: GO:0002922 {is_inferred="true"} ! positive regulation of humoral immune response
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 
 [Term]
 id: GO:0002761 ! regulation of myeloid leukocyte differentiation
@@ -4639,6 +4637,10 @@
 is_a: GO:0099095 {is_inferred="true"} ! ligand-gated anion channel activity
 
 [Term]
+id: GO:0005231 ! excitatory extracellular ligand-gated ion channel activity
+is_a: GO:0004888 {is_inferred="true"} ! transmembrane signaling receptor activity
+
+[Term]
 id: GO:0005242 ! inward rectifier potassium channel activity
 is_a: GO:0099094 {is_inferred="true"} ! ligand-gated cation channel activity
 
@@ -8548,7 +8550,6 @@
 is_a: GO:0002832 {is_inferred="true"} ! negative regulation of response to biotic stimulus
 is_a: GO:0002921 {is_inferred="true"} ! negative regulation of humoral immune response
 is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
-is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 
 [Term]
 id: GO:0008354 ! germ cell migration
@@ -10101,7 +10102,7 @@
 is_a: GO:0098543 {is_inferred="true"} ! detection of other organism
 
 [Term]
-id: GO:0009615 ! response to virus
+id: GO:0009616 ! virus induced gene silencing
 is_a: GO:0016032 {is_inferred="true"} ! viral process
 
 [Term]
@@ -10962,7 +10963,6 @@
 id: GO:0010112 ! regulation of systemic acquired resistance
 is_a: GO:0002831 {is_inferred="true"} ! regulation of response to biotic stimulus
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 is_a: GO:0045088 {is_inferred="true"} ! regulation of innate immune response
 
 [Term]
@@ -10970,7 +10970,6 @@
 is_a: GO:0002832 {is_inferred="true"} ! negative regulation of response to biotic stimulus
 is_a: GO:0010112 {is_inferred="true"} ! regulation of systemic acquired resistance
 is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
-is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:0045824 {is_inferred="true"} ! negative regulation of innate immune response
 
 [Term]
@@ -19502,8 +19501,10 @@
 is_a: GO:0005267 {is_inferred="true"} ! potassium channel activity
 
 [Term]
-id: GO:0022848 ! acetylcholine-gated cation channel activity
+id: GO:0022848 ! acetylcholine-gated cation-selective channel activity
 is_a: GO:0015464 {is_inferred="true"} ! acetylcholine receptor activity
+is_a: GO:0099094 {is_inferred="true"} ! ligand-gated cation channel activity
+is_a: GO:1904315 {is_inferred="true"} ! transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
 
 [Term]
 id: GO:0022849 ! glutamate-gated calcium ion channel activity
@@ -21204,15 +21205,18 @@
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 
 [Term]
+id: GO:0031152 ! aggregation involved in sorocarp development
+is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
+
+[Term]
 id: GO:0031155 ! regulation of reproductive fruiting body development
 is_a: GO:0075260 {is_inferred="true"} ! regulation of spore-bearing organ development
 
 [Term]
 id: GO:0031156 ! regulation of sorocarp development
-is_a: GO:0010646 {is_inferred="true"} ! regulation of cell communication
-is_a: GO:0032107 {is_inferred="true"} ! regulation of response to nutrient levels
-is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
-is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
+is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
+is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
 
 [Term]
 id: GO:0031161 ! phosphatidylinositol catabolic process
@@ -21409,14 +21413,14 @@
 
 [Term]
 id: GO:0031286 ! negative regulation of sorocarp stalk cell differentiation
-is_a: GO:0010648 {is_inferred="true"} ! negative regulation of cell communication
 is_a: GO:0031285 {is_inferred="true"} ! regulation of sorocarp stalk cell differentiation
+is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
 
 [Term]
 id: GO:0031287 ! positive regulation of sorocarp stalk cell differentiation
-is_a: GO:0010647 {is_inferred="true"} ! positive regulation of cell communication
 is_a: GO:0031285 {is_inferred="true"} ! regulation of sorocarp stalk cell differentiation
+is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
 
 [Term]
@@ -22183,7 +22187,6 @@
 is_a: GO:0002831 {is_inferred="true"} ! regulation of response to biotic stimulus
 is_a: GO:0009966 {is_inferred="true"} ! regulation of signal transduction
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 
 [Term]
 id: GO:0031665 ! negative regulation of lipopolysaccharide-mediated signaling pathway
@@ -22191,7 +22194,6 @@
 is_a: GO:0009968 {is_inferred="true"} ! negative regulation of signal transduction
 is_a: GO:0031664 {is_inferred="true"} ! regulation of lipopolysaccharide-mediated signaling pathway
 is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
-is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 
 [Term]
 id: GO:0031666 ! positive regulation of lipopolysaccharide-mediated signaling pathway
@@ -22199,7 +22201,6 @@
 is_a: GO:0009967 {is_inferred="true"} ! positive regulation of signal transduction
 is_a: GO:0031664 {is_inferred="true"} ! regulation of lipopolysaccharide-mediated signaling pathway
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 
 [Term]
 id: GO:0031670 ! cellular response to nutrient
@@ -29984,11 +29985,6 @@
 is_a: GO:0098657 {is_inferred="true"} ! import into cell
 
 [Term]
-id: GO:0036360 ! sorocarp stalk morphogenesis
-is_a: GO:0003006 {is_inferred="true"} ! developmental process involved in reproduction
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-
-[Term]
 id: GO:0036375 ! Kibra-Ex-Mer complex
 is_a: GO:0044464 {is_inferred="true"} ! cell part
 
@@ -32009,6 +32005,11 @@
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
+id: GO:0042780 ! tRNA 3'-end processing
+is_a: GO:0008033 {is_inferred="true"} ! tRNA processing
+is_a: GO:0043628 {is_inferred="true"} ! ncRNA 3'-end processing
+
+[Term]
 id: GO:0042787 ! protein ubiquitination involved in ubiquitin-dependent protein catabolic process
 is_a: GO:0016567 {is_inferred="true"} ! protein ubiquitination
 
@@ -41174,11 +41175,6 @@
 is_a: GO:0048308 {is_inferred="true"} ! organelle inheritance
 
 [Term]
-id: GO:0048315 ! conidium formation
-is_a: GO:0003006 {is_inferred="true"} ! developmental process involved in reproduction
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-
-[Term]
 id: GO:0048316 ! seed development
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
@@ -42239,7 +42235,6 @@
 is_a: GO:0002832 {is_inferred="true"} ! negative regulation of response to biotic stimulus
 is_a: GO:0031348 {is_inferred="true"} ! negative regulation of defense response
 is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
-is_a: GO:0048525 {is_inferred="true"} ! negative regulation of viral process
 is_a: GO:0050688 {is_inferred="true"} ! regulation of defense response to virus
 
 [Term]
@@ -42248,7 +42243,6 @@
 is_a: GO:0002831 {is_inferred="true"} ! regulation of response to biotic stimulus
 is_a: GO:0031347 {is_inferred="true"} ! regulation of defense response
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
-is_a: GO:0050792 {is_inferred="true"} ! regulation of viral process
 
 [Term]
 id: GO:0050696 ! trichloroethylene catabolic process
@@ -45869,7 +45863,10 @@
 
 [Term]
 id: GO:0060176 ! regulation of aggregation involved in sorocarp development
+is_a: GO:0010646 {is_inferred="true"} ! regulation of cell communication
 is_a: GO:0031156 {is_inferred="true"} ! regulation of sorocarp development
+is_a: GO:0032107 {is_inferred="true"} ! regulation of response to nutrient levels
+is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
 
 [Term]
 id: GO:0060178 ! regulation of exocyst localization
@@ -49007,11 +49004,6 @@
 is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
 [Term]
-id: GO:0061794 ! conidium development
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0048837 {is_inferred="true"} ! sorus development
-
-[Term]
 id: GO:0061796 ! membrane addition at site of mitotic cytokinesis
 is_a: GO:1902410 {is_inferred="true"} ! mitotic cytokinetic process
 
@@ -49072,7 +49064,7 @@
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
 [Term]
-id: GO:0070022 ! transforming growth factor beta receptor homodimeric complex
+id: GO:0070022 ! transforming growth factor beta receptor complex
 is_a: GO:0098802 {is_inferred="true"} ! plasma membrane receptor complex
 is_a: GO:1902554 {is_inferred="true"} ! serine/threonine protein kinase complex
 
@@ -50762,8 +50754,8 @@
 
 [Term]
 id: GO:0070900 ! mitochondrial tRNA modification
-is_a: GO:0000963 {is_inferred="true"} ! mitochondrial RNA processing
 is_a: GO:0006400 {is_inferred="true"} ! tRNA modification
+is_a: GO:0090646 {is_inferred="true"} ! mitochondrial tRNA processing
 is_a: GO:1900864 {is_inferred="true"} ! mitochondrial RNA modification
 
 [Term]
@@ -55046,32 +55038,22 @@
 [Term]
 id: GO:0075306 ! regulation of conidium formation
 is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
-is_a: GO:0031156 {is_inferred="true"} ! regulation of sorocarp development
 is_a: GO:0034305 {is_inferred="true"} ! regulation of asexual sporulation
 is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
-is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
 
 [Term]
 id: GO:0075307 ! positive regulation of conidium formation
-is_a: GO:0010647 {is_inferred="true"} ! positive regulation of cell communication
 is_a: GO:0010720 {is_inferred="true"} ! positive regulation of cell development
-is_a: GO:0032109 {is_inferred="true"} ! positive regulation of response to nutrient levels
 is_a: GO:0043938 {is_inferred="true"} ! positive regulation of sporulation
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:0075306 {is_inferred="true"} ! regulation of conidium formation
 is_a: GO:1903666 {is_inferred="true"} ! positive regulation of asexual reproduction
-is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
 
 [Term]
 id: GO:0075308 ! negative regulation of conidium formation
-is_a: GO:0010648 {is_inferred="true"} ! negative regulation of cell communication
 is_a: GO:0010721 {is_inferred="true"} ! negative regulation of cell development
-is_a: GO:0032108 {is_inferred="true"} ! negative regulation of response to nutrient levels
 is_a: GO:0043939 {is_inferred="true"} ! negative regulation of sporulation
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:0075306 {is_inferred="true"} ! regulation of conidium formation
 is_a: GO:1903665 {is_inferred="true"} ! negative regulation of asexual reproduction
-is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
 
 [Term]
 id: GO:0075310 ! regulation of sporangium development
@@ -57097,11 +57079,6 @@
 is_a: GO:0098815 {is_inferred="true"} ! modulation of excitatory postsynaptic potential
 
 [Term]
-id: GO:0090401 ! viral-induced premature senescence
-is_a: GO:0044111 {is_inferred="true"} ! development involved in symbiotic interaction
-is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
-
-[Term]
 id: GO:0090407 ! organophosphate biosynthetic process
 is_a: GO:0019637 {is_inferred="true"} ! organophosphate metabolic process
 is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
@@ -57383,6 +57360,11 @@
 is_a: GO:0098795 {is_inferred="true"} ! mRNA cleavage involved in gene silencing
 
 [Term]
+id: GO:0090646 ! mitochondrial tRNA processing
+is_a: GO:0000963 {is_inferred="true"} ! mitochondrial RNA processing
+is_a: GO:0008033 {is_inferred="true"} ! tRNA processing
+
+[Term]
 id: GO:0090688 ! cleavage furrow rim
 is_a: GO:0032155 {is_inferred="true"} ! cell division site part
 
@@ -58075,7 +58057,9 @@
 
 [Term]
 id: GO:0097745 ! mitochondrial tRNA 5'-end processing
-is_a: GO:0034471 {is_inferred="true"} ! ncRNA 5'-end processing
+is_a: GO:0000964 {is_inferred="true"} ! mitochondrial RNA 5'-end processing
+is_a: GO:0090646 {is_inferred="true"} ! mitochondrial tRNA processing
+is_a: GO:0099116 {is_inferred="true"} ! tRNA 5'-end processing
 
 [Term]
 id: GO:0097746 ! regulation of blood vessel diameter
@@ -59784,6 +59768,11 @@
 is_a: GO:0006342 {is_inferred="true"} ! chromatin silencing
 
 [Term]
+id: GO:0099116 ! tRNA 5'-end processing
+is_a: GO:0008033 {is_inferred="true"} ! tRNA processing
+is_a: GO:0034471 {is_inferred="true"} ! ncRNA 5'-end processing
+
+[Term]
 id: GO:0099117 ! protein transport along microtubule to cell tip
 is_a: GO:0098840 {is_inferred="true"} ! protein transport along microtubule
 is_a: GO:1990151 {is_inferred="true"} ! protein localization to cell tip
@@ -59794,6 +59783,24 @@
 is_a: GO:0099111 {is_inferred="true"} ! microtubule-based transport
 
 [Term]
+id: GO:0099123 ! somato-dendritic dopamine secretion
+is_a: GO:0014046 {is_inferred="true"} ! dopamine secretion
+is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
+
+[Term]
+id: GO:0099124 ! axonal dopamine secretion
+is_a: GO:0014046 {is_inferred="true"} ! dopamine secretion
+is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
+
+[Term]
+id: GO:0099125 ! PAK family kinase-Sog2 complex
+is_a: GO:1902911 {is_inferred="true"} ! protein kinase complex
+
+[Term]
+id: GO:0099126 ! transforming growth factor beta complex
+is_a: GO:0044420 {is_inferred="true"} ! extracellular matrix component
+
+[Term]
 id: GO:0099400 ! caveola neck
 is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
 
@@ -61245,7 +61252,6 @@
 is_a: GO:0002831 {is_inferred="true"} ! regulation of response to biotic stimulus
 is_a: GO:0031347 {is_inferred="true"} ! regulation of defense response
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 
 [Term]
 id: GO:1900151 ! regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
@@ -61700,7 +61706,6 @@
 is_a: GO:0031349 {is_inferred="true"} ! positive regulation of defense response
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
 is_a: GO:0039533 {is_inferred="true"} ! regulation of MDA-5 signaling pathway
-is_a: GO:0048524 {is_inferred="true"} ! positive regulation of viral process
 is_a: GO:1902533 {is_inferred="true"} ! positive regulation of intracellular signal transduction
 
 [Term]
@@ -61710,7 +61715,6 @@
 is_a: GO:0031349 {is_inferred="true"} ! positive regulation of defense response
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
 is_a: GO:0039535 {is_inferred="true"} ! regulation of RIG-I signaling pathway
-is_a: GO:0048524 {is_inferred="true"} ! positive regulation of viral process
 is_a: GO:1902533 {is_inferred="true"} ! positive regulation of intracellular signal transduction
 
 [Term]
@@ -62315,7 +62319,6 @@
 is_a: GO:0002832 {is_inferred="true"} ! negative regulation of response to biotic stimulus
 is_a: GO:0031348 {is_inferred="true"} ! negative regulation of defense response
 is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
-is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:2000068 {is_inferred="true"} ! regulation of defense response to insect
 
 [Term]
@@ -62323,7 +62326,6 @@
 is_a: GO:0002833 {is_inferred="true"} ! positive regulation of response to biotic stimulus
 is_a: GO:0031349 {is_inferred="true"} ! positive regulation of defense response
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:2000068 {is_inferred="true"} ! regulation of defense response to insect
 
 [Term]
@@ -62593,7 +62595,6 @@
 is_a: GO:0002831 {is_inferred="true"} ! regulation of response to biotic stimulus
 is_a: GO:0031347 {is_inferred="true"} ! regulation of defense response
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 
 [Term]
 id: GO:1900425 ! negative regulation of defense response to bacterium
@@ -62600,7 +62601,6 @@
 is_a: GO:0002832 {is_inferred="true"} ! negative regulation of response to biotic stimulus
 is_a: GO:0031348 {is_inferred="true"} ! negative regulation of defense response
 is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
-is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:1900424 {is_inferred="true"} ! regulation of defense response to bacterium
 
 [Term]
@@ -62608,7 +62608,6 @@
 is_a: GO:0002833 {is_inferred="true"} ! positive regulation of response to biotic stimulus
 is_a: GO:0031349 {is_inferred="true"} ! positive regulation of defense response
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:1900424 {is_inferred="true"} ! regulation of defense response to bacterium
 
 [Term]
@@ -67119,19 +67118,15 @@
 
 [Term]
 id: GO:1901262 ! negative regulation of sorocarp spore cell differentiation
-is_a: GO:0010648 {is_inferred="true"} ! negative regulation of cell communication
-is_a: GO:0032108 {is_inferred="true"} ! negative regulation of response to nutrient levels
+is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1901261 {is_inferred="true"} ! regulation of sorocarp spore cell differentiation
 is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
 
 [Term]
 id: GO:1901263 ! positive regulation of sorocarp spore cell differentiation
-is_a: GO:0010647 {is_inferred="true"} ! positive regulation of cell communication
-is_a: GO:0032109 {is_inferred="true"} ! positive regulation of response to nutrient levels
+is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1901261 {is_inferred="true"} ! regulation of sorocarp spore cell differentiation
 is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
 
@@ -69084,7 +69079,6 @@
 is_a: GO:0002833 {is_inferred="true"} ! positive regulation of response to biotic stimulus
 is_a: GO:0010112 {is_inferred="true"} ! regulation of systemic acquired resistance
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:0045089 {is_inferred="true"} ! positive regulation of innate immune response
 
 [Term]
@@ -72240,7 +72234,6 @@
 is_a: GO:0002831 {is_inferred="true"} ! regulation of response to biotic stimulus
 is_a: GO:0031347 {is_inferred="true"} ! regulation of defense response
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 
 [Term]
 id: GO:1902289 ! negative regulation of defense response to oomycetes
@@ -72247,7 +72240,6 @@
 is_a: GO:0002832 {is_inferred="true"} ! negative regulation of response to biotic stimulus
 is_a: GO:0031348 {is_inferred="true"} ! negative regulation of defense response
 is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
-is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:1902288 {is_inferred="true"} ! regulation of defense response to oomycetes
 
 [Term]
@@ -72255,7 +72247,6 @@
 is_a: GO:0002833 {is_inferred="true"} ! positive regulation of response to biotic stimulus
 is_a: GO:0031349 {is_inferred="true"} ! positive regulation of defense response
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:1902288 {is_inferred="true"} ! regulation of defense response to oomycetes
 
 [Term]
@@ -75730,15 +75721,16 @@
 
 [Term]
 id: GO:1903048 ! regulation of acetylcholine-gated cation channel activity
-is_a: GO:0032412 {is_inferred="true"} ! regulation of ion transmembrane transporter activity
-is_a: GO:0099601 {is_inferred="true"} ! regulation of neurotransmitter receptor activity
+is_a: GO:0098815 {is_inferred="true"} ! modulation of excitatory postsynaptic potential
+is_a: GO:0098962 {is_inferred="true"} ! regulation of postsynaptic neurotransmitter receptor activity
+is_a: GO:2001257 {is_inferred="true"} ! regulation of cation channel activity
 
 [Term]
 id: GO:1903049 ! negative regulation of acetylcholine-gated cation channel activity
-is_a: GO:0009968 {is_inferred="true"} ! negative regulation of signal transduction
-is_a: GO:0032413 {is_inferred="true"} ! negative regulation of ion transmembrane transporter activity
+is_a: GO:0090394 {is_inferred="true"} ! negative regulation of excitatory postsynaptic potential
 is_a: GO:1903048 {is_inferred="true"} ! regulation of acetylcholine-gated cation channel activity
 is_a: GO:2000272 {is_inferred="true"} ! negative regulation of receptor activity
+is_a: GO:2001258 {is_inferred="true"} ! negative regulation of cation channel activity
 
 [Term]
 id: GO:1903050 ! regulation of proteolysis involved in cellular protein catabolic process
@@ -82207,7 +82199,6 @@
 is_a: GO:0016241 {is_inferred="true"} ! regulation of macroautophagy
 is_a: GO:0031347 {is_inferred="true"} ! regulation of defense response
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 
 [Term]
 id: GO:1904416 ! negative regulation of xenophagy
@@ -82215,7 +82206,6 @@
 is_a: GO:0016242 {is_inferred="true"} ! negative regulation of macroautophagy
 is_a: GO:0031348 {is_inferred="true"} ! negative regulation of defense response
 is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
-is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:1904415 {is_inferred="true"} ! regulation of xenophagy
 
 [Term]
@@ -82224,7 +82214,6 @@
 is_a: GO:0016239 {is_inferred="true"} ! positive regulation of macroautophagy
 is_a: GO:0031349 {is_inferred="true"} ! positive regulation of defense response
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:1904415 {is_inferred="true"} ! regulation of xenophagy
 
 [Term]
@@ -85250,7 +85239,6 @@
 id: GO:1905035 ! negative regulation of antifungal innate immune response
 is_a: GO:0002832 {is_inferred="true"} ! negative regulation of response to biotic stimulus
 is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
-is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:0045824 {is_inferred="true"} ! negative regulation of innate immune response
 is_a: GO:1905034 {is_inferred="true"} ! regulation of antifungal innate immune response
 
@@ -85258,7 +85246,6 @@
 id: GO:1905036 ! positive regulation of antifungal innate immune response
 is_a: GO:0002833 {is_inferred="true"} ! positive regulation of response to biotic stimulus
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:0045089 {is_inferred="true"} ! positive regulation of innate immune response
 is_a: GO:1905034 {is_inferred="true"} ! regulation of antifungal innate immune response
 
@@ -89965,7 +89952,6 @@
 is_a: GO:0002831 {is_inferred="true"} ! regulation of response to biotic stimulus
 is_a: GO:0031347 {is_inferred="true"} ! regulation of defense response
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 
 [Term]
 id: GO:2000069 ! regulation of post-embryonic root development
------------------------------------------------------------------------
r37531 | paola | 2016-12-07 07:06:09 -0800 (Wed, 07 Dec 2016) | 2 lines

Added synonyms to 'centriole' as raised during revision of cilia GO paper.

changes in entailments

------------------------------------------------------------------------
r37529 | termgenie | 2016-12-07 06:23:49 -0800 (Wed, 07 Dec 2016) | 4 lines

TermGenie commit for user: ValWood reviewed by ukemi

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37529)
+++ go_inferences.obo	(working copy)
@@ -88597,6 +88597,20 @@
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
 
 [Term]
+id: GO:1905744 ! regulation of mRNA cis splicing, via spliceosome
+is_a: GO:0048024 {is_inferred="true"} ! regulation of mRNA splicing, via spliceosome
+
+[Term]
+id: GO:1905745 ! negative regulation of mRNA cis splicing, via spliceosome
+is_a: GO:0048025 {is_inferred="true"} ! negative regulation of mRNA splicing, via spliceosome
+is_a: GO:1905744 {is_inferred="true"} ! regulation of mRNA cis splicing, via spliceosome
+
+[Term]
+id: GO:1905746 ! positive regulation of mRNA cis splicing, via spliceosome
+is_a: GO:0048026 {is_inferred="true"} ! positive regulation of mRNA splicing, via spliceosome
+is_a: GO:1905744 {is_inferred="true"} ! regulation of mRNA cis splicing, via spliceosome
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37527 | davidos | 2016-12-06 19:21:28 -0800 (Tue, 06 Dec 2016) | 1 line

P-body; tRNA proc; transport to cell tip

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37527)
+++ go_inferences.obo	(working copy)
@@ -58813,6 +58813,7 @@
 id: GO:0098840 ! protein transport along microtubule
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0010970 {is_inferred="true"} ! transport along microtubule
+is_a: GO:0099118 {is_inferred="true"} ! microtubule-based protein transport
 
 [Term]
 id: GO:0098841 ! protein localization to cell division site after cytokinesis
@@ -59757,6 +59758,7 @@
 id: GO:0099110 ! microtubule polymerization based protein transport to cell tip cortex
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0099112 {is_inferred="true"} ! microtubule polymerization based protein transport
+is_a: GO:0099118 {is_inferred="true"} ! microtubule-based protein transport
 is_a: GO:1990896 {is_inferred="true"} ! protein localization to cell cortex of cell tip
 
 [Term]
@@ -59782,6 +59784,16 @@
 is_a: GO:0006342 {is_inferred="true"} ! chromatin silencing
 
 [Term]
+id: GO:0099117 ! protein transport along microtubule to cell tip
+is_a: GO:0098840 {is_inferred="true"} ! protein transport along microtubule
+is_a: GO:1990151 {is_inferred="true"} ! protein localization to cell tip
+
+[Term]
+id: GO:0099118 ! microtubule-based protein transport
+is_a: GO:0015031 {is_inferred="true"} ! protein transport
+is_a: GO:0099111 {is_inferred="true"} ! microtubule-based transport
+
+[Term]
 id: GO:0099400 ! caveola neck
 is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
 
------------------------------------------------------------------------
r37523 | paola | 2016-12-06 06:16:28 -0800 (Tue, 06 Dec 2016) | 2 lines

GH NTR/OTR: multiciliation-related classes #12672 - work in progress - merged ’ciliary basal body duplication’ into ‘centriole replication’

changes in entailments

------------------------------------------------------------------------
r37522 | termgenie | 2016-12-06 06:12:38 -0800 (Tue, 06 Dec 2016) | 2 lines

TermGenie commit for user: rjdodson reviewed by ukemi

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37522)
+++ go_inferences.obo	(working copy)
@@ -88576,6 +88576,10 @@
 is_a: GO:0099533 {is_inferred="true"} ! positive regulation of presynaptic cytosolic calcium concentration
 
 [Term]
+id: GO:1905742 ! Ras guanyl-nucleotide exchange factor complex
+is_a: GO:0032045 {is_inferred="true"} ! guanyl-nucleotide exchange factor complex
+
+[Term]
 id: GO:1905743 ! mitochondrial calcium uptake involved in negative regulation of presynaptic cytosolic calcium concentration
 is_a: GO:0036444 {is_inferred="true"} ! mitochondrial calcium uptake
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
------------------------------------------------------------------------
r37516 | paola | 2016-12-06 03:54:05 -0800 (Tue, 06 Dec 2016) | 2 lines

GH NTR/OTR: multiciliation-related classes #12672 - work in progress - edited def of 'centriole replication'

changes in entailments

------------------------------------------------------------------------
r37514 | termgenie | 2016-12-06 02:55:52 -0800 (Tue, 06 Dec 2016) | 2 lines

TermGenie commit for user: dosumis reviewed by dosumis

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37514)
+++ go_inferences.obo	(working copy)
@@ -88576,6 +88576,11 @@
 is_a: GO:0099533 {is_inferred="true"} ! positive regulation of presynaptic cytosolic calcium concentration
 
 [Term]
+id: GO:1905743 ! mitochondrial calcium uptake involved in negative regulation of presynaptic cytosolic calcium concentration
+is_a: GO:0036444 {is_inferred="true"} ! mitochondrial calcium uptake
+is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37512 | termgenie | 2016-12-06 02:09:54 -0800 (Tue, 06 Dec 2016) | 2 lines

TermGenie commit for user: dosumis reviewed by dosumis

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37512)
+++ go_inferences.obo	(working copy)
@@ -88571,6 +88571,11 @@
 is_a: GO:1905735 {is_inferred="true"} ! regulation of L-proline import across plasma membrane
 
 [Term]
+id: GO:1905741 ! mitochondrial calcium release involved in positive regulation of presynaptic cytosolic calcium concentration
+is_a: GO:0099093 {is_inferred="true"} ! mitochondrial calcium release
+is_a: GO:0099533 {is_inferred="true"} ! positive regulation of presynaptic cytosolic calcium concentration
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37507 | termgenie | 2016-12-05 11:54:04 -0800 (Mon, 05 Dec 2016) | 4 lines

TermGenie commit for user: ValWood reviewed by ukemi

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37507)
+++ go_inferences.obo	(working copy)
@@ -75054,6 +75054,7 @@
 
 [Term]
 id: GO:1902897 ! regulation of postsynaptic density protein 95 clustering
+is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
 is_a: GO:1901626 {is_inferred="true"} ! regulation of postsynaptic membrane organization
 is_a: GO:1905475 {is_inferred="true"} ! regulation of protein localization to membrane
 
@@ -88550,6 +88551,26 @@
 is_a: GO:0035372 {is_inferred="true"} ! protein localization to microtubule
 
 [Term]
+id: GO:1905735 ! regulation of L-proline import across plasma membrane
+is_a: GO:1902834 {is_inferred="true"} ! regulation of proline import into cell
+is_a: GO:1903789 {is_inferred="true"} ! regulation of amino acid transmembrane transport
+is_a: GO:1904062 {is_inferred="true"} ! regulation of cation transmembrane transport
+
+[Term]
+id: GO:1905736 ! negative regulation of L-proline import across plasma membrane
+is_a: GO:1902835 {is_inferred="true"} ! negative regulation of proline import into cell
+is_a: GO:1903960 {is_inferred="true"} ! negative regulation of anion transmembrane transport
+is_a: GO:1904063 {is_inferred="true"} ! negative regulation of cation transmembrane transport
+is_a: GO:1905735 {is_inferred="true"} ! regulation of L-proline import across plasma membrane
+
+[Term]
+id: GO:1905737 ! positive regulation of L-proline import across plasma membrane
+is_a: GO:1902836 {is_inferred="true"} ! positive regulation of proline import into cell
+is_a: GO:1903961 {is_inferred="true"} ! positive regulation of anion transmembrane transport
+is_a: GO:1904064 {is_inferred="true"} ! positive regulation of cation transmembrane transport
+is_a: GO:1905735 {is_inferred="true"} ! regulation of L-proline import across plasma membrane
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37471 | dph | 2016-12-02 05:26:21 -0800 (Fri, 02 Dec 2016) | 2 lines

Changed the name of DNA ring activity to be more consistent with the literature.

changes in entailments

------------------------------------------------------------------------
r37467 | paola | 2016-12-02 02:54:38 -0800 (Fri, 02 Dec 2016) | 3 lines

GH NTR: 3′to 5′ RNA polymerase activity #12812 - more work - see ticket for details

changes in entailments

------------------------------------------------------------------------
r37465 | paola | 2016-12-02 02:19:03 -0800 (Fri, 02 Dec 2016) | 2 lines

Removed RO stanzas

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37465)
+++ go_inferences.obo	(working copy)
@@ -1076,23 +1076,23 @@
 
 [Term]
 id: GO:0001054 ! RNA polymerase I activity
-is_a: GO:0003899 {is_inferred="true"} ! DNA-directed RNA polymerase activity
+is_a: GO:0003899 {is_inferred="true"} ! DNA-directed 5'-3' RNA polymerase activity
 
 [Term]
 id: GO:0001055 ! RNA polymerase II activity
-is_a: GO:0003899 {is_inferred="true"} ! DNA-directed RNA polymerase activity
+is_a: GO:0003899 {is_inferred="true"} ! DNA-directed 5'-3' RNA polymerase activity
 
 [Term]
 id: GO:0001056 ! RNA polymerase III activity
-is_a: GO:0003899 {is_inferred="true"} ! DNA-directed RNA polymerase activity
+is_a: GO:0003899 {is_inferred="true"} ! DNA-directed 5'-3' RNA polymerase activity
 
 [Term]
 id: GO:0001057 ! RNA polymerase IV activity
-is_a: GO:0003899 {is_inferred="true"} ! DNA-directed RNA polymerase activity
+is_a: GO:0003899 {is_inferred="true"} ! DNA-directed 5'-3' RNA polymerase activity
 
 [Term]
 id: GO:0001058 ! RNA polymerase V activity
-is_a: GO:0003899 {is_inferred="true"} ! DNA-directed RNA polymerase activity
+is_a: GO:0003899 {is_inferred="true"} ! DNA-directed 5'-3' RNA polymerase activity
 
 [Term]
 id: GO:0001083 ! transcription factor activity, RNA polymerase II basal transcription factor binding
@@ -61736,20 +61736,20 @@
 is_a: GO:2000273 {is_inferred="true"} ! positive regulation of receptor activity
 
 [Term]
-id: GO:1900259 ! regulation of RNA-directed RNA polymerase activity
+id: GO:1900259 ! regulation of RNA-directed 5'-3' RNA polymerase activity
 is_a: GO:0051338 {is_inferred="true"} ! regulation of transferase activity
 is_a: GO:1903506 {is_inferred="true"} ! regulation of nucleic acid-templated transcription
 
 [Term]
-id: GO:1900260 ! negative regulation of RNA-directed RNA polymerase activity
+id: GO:1900260 ! negative regulation of RNA-directed 5'-3' RNA polymerase activity
 is_a: GO:0051348 {is_inferred="true"} ! negative regulation of transferase activity
-is_a: GO:1900259 {is_inferred="true"} ! regulation of RNA-directed RNA polymerase activity
+is_a: GO:1900259 {is_inferred="true"} ! regulation of RNA-directed 5'-3' RNA polymerase activity
 is_a: GO:1903507 {is_inferred="true"} ! negative regulation of nucleic acid-templated transcription
 
 [Term]
-id: GO:1900261 ! positive regulation of RNA-directed RNA polymerase activity
+id: GO:1900261 ! positive regulation of RNA-directed 5'-3' RNA polymerase activity
 is_a: GO:0051347 {is_inferred="true"} ! positive regulation of transferase activity
-is_a: GO:1900259 {is_inferred="true"} ! regulation of RNA-directed RNA polymerase activity
+is_a: GO:1900259 {is_inferred="true"} ! regulation of RNA-directed 5'-3' RNA polymerase activity
 is_a: GO:1903508 {is_inferred="true"} ! positive regulation of nucleic acid-templated transcription
 
 [Term]
------------------------------------------------------------------------
r37462 | paola | 2016-12-02 01:59:16 -0800 (Fri, 02 Dec 2016) | 2 lines

GH NTRs: response to viscosity + copper ion transport across BBB/BCB #12594 - closed - added logical defs to BBB and BCB terms

changes in entailments

------------------------------------------------------------------------
r37457 | dph | 2016-12-01 17:39:41 -0800 (Thu, 01 Dec 2016) | 2 lines

Added proteaphagy. GH12839-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37457)
+++ go_inferences.obo	(working copy)
@@ -49030,6 +49030,10 @@
 is_a: GO:1902850 {is_inferred="true"} ! microtubule cytoskeleton organization involved in mitosis
 
 [Term]
+id: GO:0061816 ! proteaphagy
+is_a: GO:0035973 {is_inferred="true"} ! aggrephagy
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
------------------------------------------------------------------------
r37448 | davidos | 2016-12-01 07:29:43 -0800 (Thu, 01 Dec 2016) | 1 line

Fixed typo in namespace

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37448)
+++ go_inferences.obo	(working copy)
@@ -59156,7 +59156,7 @@
 
 [Term]
 id: GO:0098942 ! retrograde trans-synaptic signaling by trans-synaptic protein complex
-is_a: GO:0098923 {is_inferred="true"} ! retrograde trans-synaptic signaling by soluble gas
+is_a: GO:0098917 {is_inferred="true"} ! retrograde trans-synaptic signaling
 is_a: GO:0099545 {is_inferred="true"} ! trans-synaptic signaling by trans-synaptic complex
 
 [Term]
@@ -59774,6 +59774,10 @@
 is_a: GO:0099509 {is_inferred="true"} ! regulation of presynaptic cytosolic calcium ion concentration
 
 [Term]
+id: GO:0099114 ! chromatin silencing at subtelomere
+is_a: GO:0006342 {is_inferred="true"} ! chromatin silencing
+
+[Term]
 id: GO:0099400 ! caveola neck
 is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
 
@@ -60065,8 +60069,8 @@
 is_a: GO:0099622 {is_inferred="true"} ! cardiac muscle cell membrane repolarization
 
 [Term]
-id: GO:0099626 ! voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium ion concentration
-is_a: GO:0099511 {is_inferred="true"} ! voltage-gated calcium channel activity involved in regulation of cytosolic calcium ion concentration
+id: GO:0099626 ! voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels
+is_a: GO:0099511 {is_inferred="true"} ! voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels
 
 [Term]
 id: GO:0099628 ! neurotransmitter receptor diffusion trapping
@@ -60096,7 +60100,7 @@
 
 [Term]
 id: GO:0099635 ! voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels
-is_a: GO:0099626 {is_inferred="true"} ! voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium ion concentration
+is_a: GO:0099626 {is_inferred="true"} ! voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels
 
 [Term]
 id: GO:0099638 ! endosome to plasma membrane protein transport
@@ -85339,8 +85343,8 @@
 is_a: GO:0005388 {is_inferred="true"} ! calcium-transporting ATPase activity
 
 [Term]
-id: GO:1905057 ! voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration
-is_a: GO:0099511 {is_inferred="true"} ! voltage-gated calcium channel activity involved in regulation of cytosolic calcium ion concentration
+id: GO:1905057 ! voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium levels
+is_a: GO:0099511 {is_inferred="true"} ! voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels
 
 [Term]
 id: GO:1905058 ! calcium-induced calcium release activity involved in regulation of postsynaptic cytosolic calcium ion concentration
@@ -88699,6 +88703,10 @@
 is_a: GO:0034504 {is_inferred="true"} ! protein localization to nucleus
 
 [Term]
+id: GO:1990141 ! chromatin silencing at centromere outer repeat region
+is_a: GO:0030702 {is_inferred="true"} ! chromatin silencing at centromere
+
+[Term]
 id: GO:1990148 ! glutamate dehydrogenase complex
 is_a: GO:1990204 {is_inferred="true"} ! oxidoreductase complex
 
------------------------------------------------------------------------
r37407 | tberardi | 2016-11-30 09:50:37 -0800 (Wed, 30 Nov 2016) | 1 line

GH12825 merge GO:0090450 and GO:1990003 - closed

changes in entailments

------------------------------------------------------------------------
r37404 | termgenie | 2016-11-30 09:13:31 -0800 (Wed, 30 Nov 2016) | 2 lines

TermGenie commit for user: pg reviewed by tb

changes in entailments

------------------------------------------------------------------------
r37396 | davidos | 2016-11-30 07:17:13 -0800 (Wed, 30 Nov 2016) | 1 line

Removed logical def on <female gamete generation> in attempt to fix TG build.  This def was => inconsistency due to link to CL when plant gametes should also be included.  See https://github.com/geneontology/go-ontology/issues/12834

changes in entailments

------------------------------------------------------------------------
r37305 | dph | 2016-11-29 06:12:21 -0800 (Tue, 29 Nov 2016) | 2 lines

GH12829-closed. Modified the definition of ubiquitin protein ligase activity to allow for extension of linear ubiquitin chains.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37305)
+++ go_inferences.obo	(working copy)
@@ -516,18 +516,6 @@
 is_a: GO:0030203 {is_inferred="true"} ! glycosaminoglycan metabolic process
 
 [Term]
-id: GO:0000271 ! polysaccharide biosynthetic process
-is_a: GO:0005976 {is_inferred="true"} ! polysaccharide metabolic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-is_a: GO:0016051 {is_inferred="true"} ! carbohydrate biosynthetic process
-
-[Term]
-id: GO:0000272 ! polysaccharide catabolic process
-is_a: GO:0005976 {is_inferred="true"} ! polysaccharide metabolic process
-is_a: GO:0009057 {is_inferred="true"} ! macromolecule catabolic process
-is_a: GO:0016052 {is_inferred="true"} ! carbohydrate catabolic process
-
-[Term]
 id: GO:0000274 ! mitochondrial proton-transporting ATP synthase, stator stalk
 is_a: GO:0045265 {is_inferred="true"} ! proton-transporting ATP synthase, stator stalk
 is_a: GO:0098800 {is_inferred="true"} ! inner mitochondrial membrane protein complex
@@ -543,10 +531,6 @@
 is_a: GO:0098800 {is_inferred="true"} ! inner mitochondrial membrane protein complex
 
 [Term]
-id: GO:0000280 ! nuclear division
-is_a: GO:0048285 {is_inferred="true"} ! organelle fission
-
-[Term]
 id: GO:0000281 ! mitotic cytokinesis
 is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
@@ -950,10 +934,6 @@
 is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
 [Term]
-id: GO:0000820 ! regulation of glutamine family amino acid metabolic process
-is_a: GO:0006521 {is_inferred="true"} ! regulation of cellular amino acid metabolic process
-
-[Term]
 id: GO:0000821 ! regulation of arginine metabolic process
 is_a: GO:0000820 {is_inferred="true"} ! regulation of glutamine family amino acid metabolic process
 
@@ -1294,10 +1274,6 @@
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 
 [Term]
-id: GO:0001558 ! regulation of cell growth
-is_a: GO:0040008 {is_inferred="true"} ! regulation of growth
-
-[Term]
 id: GO:0001559 ! regulation of cell growth by detection of nuclear:cytoplasmic ratio
 is_a: GO:0016475 {is_inferred="true"} ! detection of nuclear:cytoplasmic ratio
 
@@ -1383,11 +1359,6 @@
 is_a: GO:0055082 {is_inferred="true"} ! cellular chemical homeostasis
 
 [Term]
-id: GO:0001692 ! histamine metabolic process
-is_a: GO:0052803 {is_inferred="true"} ! imidazole-containing compound metabolic process
-is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
-
-[Term]
 id: GO:0001694 ! histamine biosynthetic process
 is_a: GO:0001692 {is_inferred="true"} ! histamine metabolic process
 is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
@@ -1400,18 +1371,10 @@
 is_a: GO:0052805 {is_inferred="true"} ! imidazole-containing compound catabolic process
 
 [Term]
-id: GO:0001696 ! gastric acid secretion
-is_a: GO:0044707 {is_inferred="true"} ! single-multicellular organism process
-
-[Term]
 id: GO:0001739 ! sex chromatin
 is_a: GO:0005720 {is_inferred="true"} ! nuclear heterochromatin
 
 [Term]
-id: GO:0001750 ! photoreceptor outer segment
-is_a: GO:0097458 {is_inferred="true"} ! neuron part
-
-[Term]
 id: GO:0001756 ! somitogenesis
 is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
@@ -1550,10 +1513,6 @@
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 
 [Term]
-id: GO:0001820 ! serotonin secretion
-is_a: GO:0006837 {is_inferred="true"} ! serotonin transport
-
-[Term]
 id: GO:0001821 ! histamine secretion
 is_a: GO:0046903 {is_inferred="true"} ! secretion
 is_a: GO:0051608 {is_inferred="true"} ! histamine transport
@@ -1839,10 +1798,6 @@
 is_a: GO:0014075 {is_inferred="true"} ! response to amine
 
 [Term]
-id: GO:0001976 ! neurological system process involved in regulation of systemic arterial blood pressure
-is_a: GO:0050877 {is_inferred="true"} ! neurological system process
-
-[Term]
 id: GO:0001985 ! negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure
 is_a: GO:0010459 {is_inferred="true"} ! negative regulation of heart rate
 
@@ -1856,10 +1811,6 @@
 is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
 
 [Term]
-id: GO:0002018 ! renin-angiotensin regulation of aldosterone production
-is_a: GO:2000858 {is_inferred="true"} ! regulation of aldosterone secretion
-
-[Term]
 id: GO:0002028 ! regulation of sodium ion transport
 is_a: GO:0010959 {is_inferred="true"} ! regulation of metal ion transport
 
@@ -1899,11 +1850,6 @@
 is_a: GO:2000648 {is_inferred="true"} ! positive regulation of stem cell proliferation
 
 [Term]
-id: GO:0002053 ! positive regulation of mesenchymal cell proliferation
-is_a: GO:0008284 {is_inferred="true"} ! positive regulation of cell proliferation
-is_a: GO:0010464 {is_inferred="true"} ! regulation of mesenchymal cell proliferation
-
-[Term]
 id: GO:0002054 ! nucleobase binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
@@ -1977,10 +1923,6 @@
 is_a: GO:0030857 {is_inferred="true"} ! negative regulation of epithelial cell differentiation
 
 [Term]
-id: GO:0002087 ! regulation of respiratory gaseous exchange by neurological system process
-is_a: GO:0050877 {is_inferred="true"} ! neurological system process
-
-[Term]
 id: GO:0002090 ! regulation of receptor internalization
 is_a: GO:0031323 {is_inferred="true"} ! regulation of cellular metabolic process
 is_a: GO:0048259 {is_inferred="true"} ! regulation of receptor-mediated endocytosis
@@ -2136,10 +2078,6 @@
 is_a: GO:0030595 {is_inferred="true"} ! leukocyte chemotaxis
 
 [Term]
-id: GO:0002246 ! wound healing involved in inflammatory response
-is_a: GO:0042060 {is_inferred="true"} ! wound healing
-
-[Term]
 id: GO:0002256 ! regulation of kinin cascade
 is_a: GO:0002673 {is_inferred="true"} ! regulation of acute inflammatory response
 is_a: GO:2000257 {is_inferred="true"} ! regulation of protein activation cascade
@@ -2157,10 +2095,6 @@
 is_a: GO:2000259 {is_inferred="true"} ! positive regulation of protein activation cascade
 
 [Term]
-id: GO:0002263 ! cell activation involved in immune response
-is_a: GO:0001775 {is_inferred="true"} ! cell activation
-
-[Term]
 id: GO:0002264 ! endothelial cell activation involved in immune response
 is_a: GO:0002263 {is_inferred="true"} ! cell activation involved in immune response
 is_a: GO:0042118 {is_inferred="true"} ! endothelial cell activation
@@ -2176,10 +2110,6 @@
 is_a: GO:0002266 {is_inferred="true"} ! follicular dendritic cell activation
 
 [Term]
-id: GO:0002269 ! leukocyte activation involved in inflammatory response
-is_a: GO:0045321 {is_inferred="true"} ! leukocyte activation
-
-[Term]
 id: GO:0002271 ! plasmacytoid dendritic cell activation involved in immune response
 is_a: GO:0002270 {is_inferred="true"} ! plasmacytoid dendritic cell activation
 is_a: GO:0002366 {is_inferred="true"} ! leukocyte activation involved in immune response
@@ -2232,16 +2162,6 @@
 is_a: GO:0043011 {is_inferred="true"} ! myeloid dendritic cell differentiation
 
 [Term]
-id: GO:0002285 ! lymphocyte activation involved in immune response
-is_a: GO:0002366 {is_inferred="true"} ! leukocyte activation involved in immune response
-is_a: GO:0046649 {is_inferred="true"} ! lymphocyte activation
-
-[Term]
-id: GO:0002286 ! T cell activation involved in immune response
-is_a: GO:0002285 {is_inferred="true"} ! lymphocyte activation involved in immune response
-is_a: GO:0042110 {is_inferred="true"} ! T cell activation
-
-[Term]
 id: GO:0002287 ! alpha-beta T cell activation involved in immune response
 is_a: GO:0002286 {is_inferred="true"} ! T cell activation involved in immune response
 is_a: GO:0046631 {is_inferred="true"} ! alpha-beta T cell activation
@@ -2262,11 +2182,6 @@
 is_a: GO:0046629 {is_inferred="true"} ! gamma-delta T cell activation
 
 [Term]
-id: GO:0002292 ! T cell differentiation involved in immune response
-is_a: GO:0002286 {is_inferred="true"} ! T cell activation involved in immune response
-is_a: GO:0030217 {is_inferred="true"} ! T cell differentiation
-
-[Term]
 id: GO:0002293 ! alpha-beta T cell differentiation involved in immune response
 is_a: GO:0002287 {is_inferred="true"} ! alpha-beta T cell activation involved in immune response
 is_a: GO:0002292 {is_inferred="true"} ! T cell differentiation involved in immune response
@@ -2315,21 +2230,6 @@
 is_a: GO:0046630 {is_inferred="true"} ! gamma-delta T cell proliferation
 
 [Term]
-id: GO:0002312 ! B cell activation involved in immune response
-is_a: GO:0002285 {is_inferred="true"} ! lymphocyte activation involved in immune response
-is_a: GO:0042113 {is_inferred="true"} ! B cell activation
-
-[Term]
-id: GO:0002313 ! mature B cell differentiation involved in immune response
-is_a: GO:0002312 {is_inferred="true"} ! B cell activation involved in immune response
-is_a: GO:0002335 {is_inferred="true"} ! mature B cell differentiation
-
-[Term]
-id: GO:0002322 ! B cell proliferation involved in immune response
-is_a: GO:0002312 {is_inferred="true"} ! B cell activation involved in immune response
-is_a: GO:0042100 {is_inferred="true"} ! B cell proliferation
-
-[Term]
 id: GO:0002323 ! natural killer cell activation involved in immune response
 is_a: GO:0002285 {is_inferred="true"} ! lymphocyte activation involved in immune response
 is_a: GO:0030101 {is_inferred="true"} ! natural killer cell activation
@@ -2353,11 +2253,6 @@
 is_a: GO:0002363 {is_inferred="true"} ! alpha-beta T cell lineage commitment
 
 [Term]
-id: GO:0002366 ! leukocyte activation involved in immune response
-is_a: GO:0002263 {is_inferred="true"} ! cell activation involved in immune response
-is_a: GO:0045321 {is_inferred="true"} ! leukocyte activation
-
-[Term]
 id: GO:0002367 ! cytokine production involved in immune response
 is_a: GO:0001816 {is_inferred="true"} ! cytokine production
 
@@ -2437,10 +2332,6 @@
 is_a: GO:0001821 {is_inferred="true"} ! histamine secretion
 
 [Term]
-id: GO:0002442 ! serotonin secretion involved in inflammatory response
-is_a: GO:0001820 {is_inferred="true"} ! serotonin secretion
-
-[Term]
 id: GO:0002467 ! germinal center formation
 is_a: GO:0048646 {is_inferred="true"} ! anatomical structure formation involved in morphogenesis
 
@@ -2543,10 +2434,30 @@
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
+id: GO:0002554 ! serotonin secretion by platelet
+is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
+
+[Term]
+id: GO:0002555 ! histamine secretion by platelet
+is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
+
+[Term]
+id: GO:0002556 ! serotonin secretion by basophil
+is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
+
+[Term]
+id: GO:0002557 ! histamine secretion by basophil
+is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
+
+[Term]
 id: GO:0002575 ! basophil chemotaxis
 is_a: GO:0071621 {is_inferred="true"} ! granulocyte chemotaxis
 
 [Term]
+id: GO:0002576 ! platelet degranulation
+is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
+
+[Term]
 id: GO:0002577 ! regulation of antigen processing and presentation
 is_a: GO:0002682 {is_inferred="true"} ! regulation of immune system process
 
@@ -2848,37 +2759,6 @@
 is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 
 [Term]
-id: GO:0002637 ! regulation of immunoglobulin production
-is_a: GO:0002700 {is_inferred="true"} ! regulation of production of molecular mediator of immune response
-
-[Term]
-id: GO:0002638 ! negative regulation of immunoglobulin production
-is_a: GO:0002637 {is_inferred="true"} ! regulation of immunoglobulin production
-is_a: GO:0002701 {is_inferred="true"} ! negative regulation of production of molecular mediator of immune response
-
-[Term]
-id: GO:0002639 ! positive regulation of immunoglobulin production
-is_a: GO:0002637 {is_inferred="true"} ! regulation of immunoglobulin production
-is_a: GO:0002702 {is_inferred="true"} ! positive regulation of production of molecular mediator of immune response
-
-[Term]
-id: GO:0002640 ! regulation of immunoglobulin biosynthetic process
-is_a: GO:0002637 {is_inferred="true"} ! regulation of immunoglobulin production
-is_a: GO:0010556 {is_inferred="true"} ! regulation of macromolecule biosynthetic process
-
-[Term]
-id: GO:0002641 ! negative regulation of immunoglobulin biosynthetic process
-is_a: GO:0002638 {is_inferred="true"} ! negative regulation of immunoglobulin production
-is_a: GO:0002640 {is_inferred="true"} ! regulation of immunoglobulin biosynthetic process
-is_a: GO:0010558 {is_inferred="true"} ! negative regulation of macromolecule biosynthetic process
-
-[Term]
-id: GO:0002642 ! positive regulation of immunoglobulin biosynthetic process
-is_a: GO:0002639 {is_inferred="true"} ! positive regulation of immunoglobulin production
-is_a: GO:0002640 {is_inferred="true"} ! regulation of immunoglobulin biosynthetic process
-is_a: GO:0010557 {is_inferred="true"} ! positive regulation of macromolecule biosynthetic process
-
-[Term]
 id: GO:0002643 ! regulation of tolerance induction
 is_a: GO:0002682 {is_inferred="true"} ! regulation of immune system process
 is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
@@ -3065,20 +2945,6 @@
 is_a: GO:0045730 {is_inferred="true"} ! respiratory burst
 
 [Term]
-id: GO:0002682 ! regulation of immune system process
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-
-[Term]
-id: GO:0002683 ! negative regulation of immune system process
-is_a: GO:0002682 {is_inferred="true"} ! regulation of immune system process
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
-
-[Term]
-id: GO:0002684 ! positive regulation of immune system process
-is_a: GO:0002682 {is_inferred="true"} ! regulation of immune system process
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
-
-[Term]
 id: GO:0002685 ! regulation of leukocyte migration
 is_a: GO:0002682 {is_inferred="true"} ! regulation of immune system process
 is_a: GO:0030334 {is_inferred="true"} ! regulation of cell migration
@@ -3127,45 +2993,6 @@
 is_a: GO:0002691 {is_inferred="true"} ! regulation of cellular extravasation
 
 [Term]
-id: GO:0002694 ! regulation of leukocyte activation
-is_a: GO:0002682 {is_inferred="true"} ! regulation of immune system process
-is_a: GO:0050865 {is_inferred="true"} ! regulation of cell activation
-
-[Term]
-id: GO:0002695 ! negative regulation of leukocyte activation
-is_a: GO:0002683 {is_inferred="true"} ! negative regulation of immune system process
-is_a: GO:0002694 {is_inferred="true"} ! regulation of leukocyte activation
-is_a: GO:0050866 {is_inferred="true"} ! negative regulation of cell activation
-
-[Term]
-id: GO:0002696 ! positive regulation of leukocyte activation
-is_a: GO:0002684 {is_inferred="true"} ! positive regulation of immune system process
-is_a: GO:0002694 {is_inferred="true"} ! regulation of leukocyte activation
-is_a: GO:0050867 {is_inferred="true"} ! positive regulation of cell activation
-
-[Term]
-id: GO:0002697 ! regulation of immune effector process
-is_a: GO:0002682 {is_inferred="true"} ! regulation of immune system process
-
-[Term]
-id: GO:0002698 ! negative regulation of immune effector process
-is_a: GO:0002683 {is_inferred="true"} ! negative regulation of immune system process
-is_a: GO:0002697 {is_inferred="true"} ! regulation of immune effector process
-
-[Term]
-id: GO:0002699 ! positive regulation of immune effector process
-is_a: GO:0002684 {is_inferred="true"} ! positive regulation of immune system process
-is_a: GO:0002697 {is_inferred="true"} ! regulation of immune effector process
-
-[Term]
-id: GO:0002701 ! negative regulation of production of molecular mediator of immune response
-is_a: GO:0002700 {is_inferred="true"} ! regulation of production of molecular mediator of immune response
-
-[Term]
-id: GO:0002702 ! positive regulation of production of molecular mediator of immune response
-is_a: GO:0002700 {is_inferred="true"} ! regulation of production of molecular mediator of immune response
-
-[Term]
 id: GO:0002703 ! regulation of leukocyte mediated immunity
 is_a: GO:0002697 {is_inferred="true"} ! regulation of immune effector process
 
@@ -3469,26 +3296,6 @@
 is_a: GO:0031348 {is_inferred="true"} ! negative regulation of defense response
 
 [Term]
-id: GO:0002790 ! peptide secretion
-is_a: GO:0015833 {is_inferred="true"} ! peptide transport
-is_a: GO:0046903 {is_inferred="true"} ! secretion
-
-[Term]
-id: GO:0002791 ! regulation of peptide secretion
-is_a: GO:0051046 {is_inferred="true"} ! regulation of secretion
-is_a: GO:0090087 {is_inferred="true"} ! regulation of peptide transport
-
-[Term]
-id: GO:0002792 ! negative regulation of peptide secretion
-is_a: GO:0002791 {is_inferred="true"} ! regulation of peptide secretion
-is_a: GO:0051048 {is_inferred="true"} ! negative regulation of secretion
-
-[Term]
-id: GO:0002793 ! positive regulation of peptide secretion
-is_a: GO:0002791 {is_inferred="true"} ! regulation of peptide secretion
-is_a: GO:0051047 {is_inferred="true"} ! positive regulation of secretion
-
-[Term]
 id: GO:0002794 ! regulation of antimicrobial peptide secretion
 is_a: GO:0002784 {is_inferred="true"} ! regulation of antimicrobial peptide production
 is_a: GO:0002791 {is_inferred="true"} ! regulation of peptide secretion
@@ -4214,28 +4021,6 @@
 is_a: GO:0019229 {is_inferred="true"} ! regulation of vasoconstriction
 
 [Term]
-id: GO:0003071 ! renal system process involved in regulation of systemic arterial blood pressure
-is_a: GO:0003014 {is_inferred="true"} ! renal system process
-
-[Term]
-id: GO:0003093 ! regulation of glomerular filtration
-is_a: GO:0098801 {is_inferred="true"} ! regulation of renal system process
-
-[Term]
-id: GO:0003097 ! renal water transport
-is_a: GO:0044707 {is_inferred="true"} ! single-multicellular organism process
-
-[Term]
-id: GO:0003104 ! positive regulation of glomerular filtration
-is_a: GO:0003093 {is_inferred="true"} ! regulation of glomerular filtration
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-
-[Term]
-id: GO:0003105 ! negative regulation of glomerular filtration
-is_a: GO:0003093 {is_inferred="true"} ! regulation of glomerular filtration
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-
-[Term]
 id: GO:0003130 ! BMP signaling pathway involved in heart induction
 is_a: GO:1905114 {is_inferred="true"} ! cell surface receptor signaling pathway involved in cell-cell signaling
 
@@ -4540,23 +4325,6 @@
 is_a: GO:0072148 {is_inferred="true"} ! epithelial cell fate commitment
 
 [Term]
-id: GO:0003330 ! regulation of extracellular matrix constituent secretion
-is_a: GO:1903053 {is_inferred="true"} ! regulation of extracellular matrix organization
-is_a: GO:1903530 {is_inferred="true"} ! regulation of secretion by cell
-
-[Term]
-id: GO:0003331 ! positive regulation of extracellular matrix constituent secretion
-is_a: GO:0003330 {is_inferred="true"} ! regulation of extracellular matrix constituent secretion
-is_a: GO:1903055 {is_inferred="true"} ! positive regulation of extracellular matrix organization
-is_a: GO:1903532 {is_inferred="true"} ! positive regulation of secretion by cell
-
-[Term]
-id: GO:0003332 ! negative regulation of extracellular matrix constituent secretion
-is_a: GO:0003330 {is_inferred="true"} ! regulation of extracellular matrix constituent secretion
-is_a: GO:1903054 {is_inferred="true"} ! negative regulation of extracellular matrix organization
-is_a: GO:1903531 {is_inferred="true"} ! negative regulation of secretion by cell
-
-[Term]
 id: GO:0003333 ! amino acid transmembrane transport
 is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
 is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
@@ -4746,10 +4514,6 @@
 is_a: GO:0045198 {is_inferred="true"} ! establishment of epithelial cell apical/basal polarity
 
 [Term]
-id: GO:0003413 ! chondrocyte differentiation involved in endochondral bone morphogenesis
-is_a: GO:0002062 {is_inferred="true"} ! chondrocyte differentiation
-
-[Term]
 id: GO:0003414 ! chondrocyte morphogenesis involved in endochondral bone morphogenesis
 is_a: GO:0090171 {is_inferred="true"} ! chondrocyte morphogenesis
 
@@ -4789,10 +4553,6 @@
 is_a: GO:0003422 {is_inferred="true"} ! growth plate cartilage morphogenesis
 
 [Term]
-id: GO:0003433 ! chondrocyte development involved in endochondral bone morphogenesis
-is_a: GO:0002063 {is_inferred="true"} ! chondrocyte development
-
-[Term]
 id: GO:0003434 ! BMP signaling pathway involved in growth plate cartilage chondrocyte development
 is_a: GO:0030509 {is_inferred="true"} ! BMP signaling pathway
 
@@ -5200,11 +4960,6 @@
 is_a: GO:0098651 {is_inferred="true"} ! basement membrane collagen trimer
 
 [Term]
-id: GO:0005587 ! collagen type IV trimer
-is_a: GO:0098642 {is_inferred="true"} ! network-forming collagen trimer
-is_a: GO:0098651 {is_inferred="true"} ! basement membrane collagen trimer
-
-[Term]
 id: GO:0005589 ! collagen type VI trimer
 is_a: GO:0044420 {is_inferred="true"} ! extracellular matrix component
 
@@ -5450,10 +5205,6 @@
 is_a: GO:0034518 {is_inferred="true"} ! RNA cap binding complex
 
 [Term]
-id: GO:0005858 ! axonemal dynein complex
-is_a: GO:0044447 {is_inferred="true"} ! axoneme part
-
-[Term]
 id: GO:0005859 ! muscle myosin complex
 is_a: GO:0016460 {is_inferred="true"} ! myosin II complex
 is_a: GO:0044449 {is_inferred="true"} ! contractile fiber part
@@ -5467,25 +5218,6 @@
 is_a: GO:0005874 {is_inferred="true"} ! microtubule
 
 [Term]
-id: GO:0005879 ! axonemal microtubule
-is_a: GO:0005874 {is_inferred="true"} ! microtubule
-is_a: GO:0044447 {is_inferred="true"} ! axoneme part
-
-[Term]
-id: GO:0005880 ! nuclear microtubule
-is_a: GO:0005874 {is_inferred="true"} ! microtubule
-is_a: GO:0044428 {is_inferred="true"} ! nuclear part
-
-[Term]
-id: GO:0005881 ! cytoplasmic microtubule
-is_a: GO:0005874 {is_inferred="true"} ! microtubule
-is_a: GO:0044444 {is_inferred="true"} ! cytoplasmic part
-
-[Term]
-id: GO:0005886 ! plasma membrane
-is_a: GO:0044464 {is_inferred="true"} ! cell part
-
-[Term]
 id: GO:0005887 ! integral component of plasma membrane
 is_a: GO:0031226 {is_inferred="true"} ! intrinsic component of plasma membrane
 
@@ -5547,10 +5279,6 @@
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
 [Term]
-id: GO:0005930 ! axoneme
-is_a: GO:0044430 {is_inferred="true"} ! cytoskeletal part
-
-[Term]
 id: GO:0005938 ! cell cortex
 is_a: GO:0099568 {is_inferred="true"} ! cytoplasmic region
 
@@ -5632,40 +5360,6 @@
 is_a: GO:1990204 {is_inferred="true"} ! oxidoreductase complex
 
 [Term]
-id: GO:0005975 ! carbohydrate metabolic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
-
-[Term]
-id: GO:0005976 ! polysaccharide metabolic process
-is_a: GO:0005975 {is_inferred="true"} ! carbohydrate metabolic process
-is_a: GO:0043170 {is_inferred="true"} ! macromolecule metabolic process
-
-[Term]
-id: GO:0005977 ! glycogen metabolic process
-is_a: GO:0044723 {is_inferred="true"} ! single-organism carbohydrate metabolic process
-
-[Term]
-id: GO:0005978 ! glycogen biosynthetic process
-is_a: GO:0005977 {is_inferred="true"} ! glycogen metabolic process
-is_a: GO:0009250 {is_inferred="true"} ! glucan biosynthetic process
-
-[Term]
-id: GO:0005979 ! regulation of glycogen biosynthetic process
-is_a: GO:0010962 {is_inferred="true"} ! regulation of glucan biosynthetic process
-is_a: GO:0070873 {is_inferred="true"} ! regulation of glycogen metabolic process
-
-[Term]
-id: GO:0005980 ! glycogen catabolic process
-is_a: GO:0005977 {is_inferred="true"} ! glycogen metabolic process
-is_a: GO:0009251 {is_inferred="true"} ! glucan catabolic process
-is_a: GO:0044724 {is_inferred="true"} ! single-organism carbohydrate catabolic process
-
-[Term]
-id: GO:0005981 ! regulation of glycogen catabolic process
-is_a: GO:0043471 {is_inferred="true"} ! regulation of cellular carbohydrate catabolic process
-is_a: GO:0070873 {is_inferred="true"} ! regulation of glycogen metabolic process
-
-[Term]
 id: GO:0005983 ! starch catabolic process
 is_a: GO:0005982 {is_inferred="true"} ! starch metabolic process
 is_a: GO:0009251 {is_inferred="true"} ! glucan catabolic process
@@ -5771,10 +5465,6 @@
 is_a: GO:0042354 {is_inferred="true"} ! L-fucose metabolic process
 
 [Term]
-id: GO:0006006 ! glucose metabolic process
-is_a: GO:0019318 {is_inferred="true"} ! hexose metabolic process
-
-[Term]
 id: GO:0006007 ! glucose catabolic process
 is_a: GO:0006006 {is_inferred="true"} ! glucose metabolic process
 is_a: GO:0019320 {is_inferred="true"} ! hexose catabolic process
@@ -5828,24 +5518,6 @@
 is_a: GO:0046173 {is_inferred="true"} ! polyol biosynthetic process
 
 [Term]
-id: GO:0006022 ! aminoglycan metabolic process
-is_a: GO:0043170 {is_inferred="true"} ! macromolecule metabolic process
-is_a: GO:1901135 {is_inferred="true"} ! carbohydrate derivative metabolic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
-
-[Term]
-id: GO:0006023 ! aminoglycan biosynthetic process
-is_a: GO:0006022 {is_inferred="true"} ! aminoglycan metabolic process
-is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
-is_a: GO:1901137 {is_inferred="true"} ! carbohydrate derivative biosynthetic process
-is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
-
-[Term]
-id: GO:0006024 ! glycosaminoglycan biosynthetic process
-is_a: GO:0006023 {is_inferred="true"} ! aminoglycan biosynthetic process
-is_a: GO:0030203 {is_inferred="true"} ! glycosaminoglycan metabolic process
-
-[Term]
 id: GO:0006025 ! galactosaminoglycan biosynthetic process
 is_a: GO:0006024 {is_inferred="true"} ! glycosaminoglycan biosynthetic process
 is_a: GO:0046350 {is_inferred="true"} ! galactosaminoglycan metabolic process
@@ -6060,16 +5732,6 @@
 is_a: GO:0005976 {is_inferred="true"} ! polysaccharide metabolic process
 
 [Term]
-id: GO:0006081 ! cellular aldehyde metabolic process
-is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
-
-[Term]
-id: GO:0006082 ! organic acid metabolic process
-is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
-
-[Term]
 id: GO:0006083 ! acetate metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 
@@ -6157,10 +5819,6 @@
 is_a: GO:0043648 {is_inferred="true"} ! dicarboxylic acid metabolic process
 
 [Term]
-id: GO:0006109 ! regulation of carbohydrate metabolic process
-is_a: GO:0080090 {is_inferred="true"} ! regulation of primary metabolic process
-
-[Term]
 id: GO:0006110 ! regulation of glycolytic process
 is_a: GO:0042325 {is_inferred="true"} ! regulation of phosphorylation
 is_a: GO:0043467 {is_inferred="true"} ! regulation of generation of precursor metabolites and energy
@@ -6881,15 +6539,6 @@
 is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
 
 [Term]
-id: GO:0006520 ! cellular amino acid metabolic process
-is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
-
-[Term]
-id: GO:0006521 ! regulation of cellular amino acid metabolic process
-is_a: GO:0080090 {is_inferred="true"} ! regulation of primary metabolic process
-
-[Term]
 id: GO:0006523 ! alanine biosynthetic process
 is_a: GO:0006522 {is_inferred="true"} ! alanine metabolic process
 
@@ -6945,10 +6594,6 @@
 is_a: GO:0019344 {is_inferred="true"} ! cysteine biosynthetic process
 
 [Term]
-id: GO:0006536 ! glutamate metabolic process
-is_a: GO:0043648 {is_inferred="true"} ! dicarboxylic acid metabolic process
-
-[Term]
 id: GO:0006537 ! glutamate biosynthetic process
 is_a: GO:0006536 {is_inferred="true"} ! glutamate metabolic process
 is_a: GO:0043650 {is_inferred="true"} ! dicarboxylic acid biosynthetic process
@@ -7117,10 +6762,6 @@
 is_a: GO:1901606 {is_inferred="true"} ! alpha-amino acid catabolic process
 
 [Term]
-id: GO:0006575 ! cellular modified amino acid metabolic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
-
-[Term]
 id: GO:0006577 ! amino-acid betaine metabolic process
 is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
 
@@ -7158,11 +6799,6 @@
 is_a: GO:0042438 {is_inferred="true"} ! melanin biosynthetic process
 
 [Term]
-id: GO:0006584 ! catecholamine metabolic process
-is_a: GO:0009712 {is_inferred="true"} ! catechol-containing compound metabolic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
-
-[Term]
 id: GO:0006585 ! dopamine biosynthetic process from tyrosine
 is_a: GO:0006570 {is_inferred="true"} ! tyrosine metabolic process
 is_a: GO:0042416 {is_inferred="true"} ! dopamine biosynthetic process
@@ -7286,10 +6922,6 @@
 is_a: GO:0070585 {is_inferred="true"} ! protein localization to mitochondrion
 
 [Term]
-id: GO:0006629 ! lipid metabolic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
-
-[Term]
 id: GO:0006631 ! fatty acid metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 
@@ -7560,12 +7192,6 @@
 is_a: GO:0006692 {is_inferred="true"} ! prostanoid metabolic process
 
 [Term]
-id: GO:0006694 ! steroid biosynthetic process
-is_a: GO:0008202 {is_inferred="true"} ! steroid metabolic process
-is_a: GO:0008610 {is_inferred="true"} ! lipid biosynthetic process
-is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
-
-[Term]
 id: GO:0006695 ! cholesterol biosynthetic process
 is_a: GO:0008203 {is_inferred="true"} ! cholesterol metabolic process
 is_a: GO:0016126 {is_inferred="true"} ! sterol biosynthetic process
@@ -7586,18 +7212,6 @@
 is_a: GO:1902653 {is_inferred="true"} ! secondary alcohol biosynthetic process
 
 [Term]
-id: GO:0006699 ! bile acid biosynthetic process
-is_a: GO:0006694 {is_inferred="true"} ! steroid biosynthetic process
-is_a: GO:0008206 {is_inferred="true"} ! bile acid metabolic process
-is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
-is_a: GO:1901617 {is_inferred="true"} ! organic hydroxy compound biosynthetic process
-
-[Term]
-id: GO:0006700 ! C21-steroid hormone biosynthetic process
-is_a: GO:0006694 {is_inferred="true"} ! steroid biosynthetic process
-is_a: GO:0008207 {is_inferred="true"} ! C21-steroid hormone metabolic process
-
-[Term]
 id: GO:0006701 ! progesterone biosynthetic process
 is_a: GO:0006700 {is_inferred="true"} ! C21-steroid hormone biosynthetic process
 is_a: GO:0042181 {is_inferred="true"} ! ketone biosynthetic process
@@ -7612,16 +7226,6 @@
 is_a: GO:0008210 {is_inferred="true"} ! estrogen metabolic process
 
 [Term]
-id: GO:0006704 ! glucocorticoid biosynthetic process
-is_a: GO:0006694 {is_inferred="true"} ! steroid biosynthetic process
-is_a: GO:0008211 {is_inferred="true"} ! glucocorticoid metabolic process
-
-[Term]
-id: GO:0006705 ! mineralocorticoid biosynthetic process
-is_a: GO:0006694 {is_inferred="true"} ! steroid biosynthetic process
-is_a: GO:0008212 {is_inferred="true"} ! mineralocorticoid metabolic process
-
-[Term]
 id: GO:0006706 ! steroid catabolic process
 is_a: GO:0008202 {is_inferred="true"} ! steroid metabolic process
 is_a: GO:0016042 {is_inferred="true"} ! lipid catabolic process
@@ -7932,10 +7536,6 @@
 is_a: GO:0072593 {is_inferred="true"} ! reactive oxygen species metabolic process
 
 [Term]
-id: GO:0006807 ! nitrogen compound metabolic process
-is_a: GO:0008152 {is_inferred="true"} ! metabolic process
-
-[Term]
 id: GO:0006808 ! regulation of nitrogen utilization
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
 
@@ -7945,14 +7545,6 @@
 is_a: GO:1903409 {is_inferred="true"} ! reactive oxygen species biosynthetic process
 
 [Term]
-id: GO:0006811 ! ion transport
-is_a: GO:0006810 {is_inferred="true"} ! transport
-
-[Term]
-id: GO:0006812 ! cation transport
-is_a: GO:0006811 {is_inferred="true"} ! ion transport
-
-[Term]
 id: GO:0006813 ! potassium ion transport
 is_a: GO:0015672 {is_inferred="true"} ! monovalent inorganic cation transport
 is_a: GO:0030001 {is_inferred="true"} ! metal ion transport
@@ -7967,10 +7559,6 @@
 is_a: GO:0015698 {is_inferred="true"} ! inorganic anion transport
 
 [Term]
-id: GO:0006820 ! anion transport
-is_a: GO:0006811 {is_inferred="true"} ! ion transport
-
-[Term]
 id: GO:0006821 ! chloride transport
 is_a: GO:0015698 {is_inferred="true"} ! inorganic anion transport
 
@@ -8000,12 +7588,6 @@
 is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
 
 [Term]
-id: GO:0006837 ! serotonin transport
-is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
-is_a: GO:0015844 {is_inferred="true"} ! monoamine transport
-is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
-
-[Term]
 id: GO:0006839 ! mitochondrial transport
 is_a: GO:0006810 {is_inferred="true"} ! transport
 
@@ -8086,10 +7668,6 @@
 is_a: GO:0006812 {is_inferred="true"} ! cation transport
 
 [Term]
-id: GO:0006869 ! lipid transport
-is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
-
-[Term]
 id: GO:0006873 ! cellular ion homeostasis
 is_a: GO:0050801 {is_inferred="true"} ! ion homeostasis
 is_a: GO:0055082 {is_inferred="true"} ! cellular chemical homeostasis
@@ -8146,10 +7724,6 @@
 is_a: GO:0048278 {is_inferred="true"} ! vesicle docking
 
 [Term]
-id: GO:0006906 ! vesicle fusion
-is_a: GO:0090174 {is_inferred="true"} ! organelle membrane fusion
-
-[Term]
 id: GO:0006910 ! phagocytosis, recognition
 is_a: GO:0008037 {is_inferred="true"} ! cell recognition
 
@@ -8162,18 +7736,6 @@
 is_a: GO:0022411 {is_inferred="true"} ! cellular component disassembly
 
 [Term]
-id: GO:0006937 ! regulation of muscle contraction
-is_a: GO:0090257 {is_inferred="true"} ! regulation of muscle system process
-
-[Term]
-id: GO:0006940 ! regulation of smooth muscle contraction
-is_a: GO:0006937 {is_inferred="true"} ! regulation of muscle contraction
-
-[Term]
-id: GO:0006942 ! regulation of striated muscle contraction
-is_a: GO:0006937 {is_inferred="true"} ! regulation of muscle contraction
-
-[Term]
 id: GO:0006963 ! positive regulation of antibacterial peptide biosynthetic process
 is_a: GO:0002803 {is_inferred="true"} ! positive regulation of antibacterial peptide production
 is_a: GO:0002807 {is_inferred="true"} ! positive regulation of antimicrobial peptide biosynthetic process
@@ -8209,10 +7771,6 @@
 is_a: GO:1901522 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
 
 [Term]
-id: GO:0006996 ! organelle organization
-is_a: GO:0016043 {is_inferred="true"} ! cellular component organization
-
-[Term]
 id: GO:0006997 ! nucleus organization
 is_a: GO:0006996 {is_inferred="true"} ! organelle organization
 
@@ -8433,10 +7991,6 @@
 is_a: GO:0022414 {is_inferred="true"} ! reproductive process
 
 [Term]
-id: GO:0007126 ! meiotic nuclear division
-is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
-
-[Term]
 id: GO:0007130 ! synaptonemal complex assembly
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
 
@@ -8465,10 +8019,6 @@
 is_a: GO:0098765 {is_inferred="true"} ! meiosis II cell cycle phase
 
 [Term]
-id: GO:0007162 ! negative regulation of cell adhesion
-is_a: GO:0030155 {is_inferred="true"} ! regulation of cell adhesion
-
-[Term]
 id: GO:0007175 ! negative regulation of epidermal growth factor-activated receptor activity
 is_a: GO:0007176 {is_inferred="true"} ! regulation of epidermal growth factor-activated receptor activity
 is_a: GO:0061099 {is_inferred="true"} ! negative regulation of protein tyrosine kinase activity
@@ -8519,11 +8069,6 @@
 is_a: GO:0099643 {is_inferred="true"} ! signal release from synapse
 
 [Term]
-id: GO:0007275 ! multicellular organism development
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
-is_a: GO:0048856 {is_inferred="true"} ! anatomical structure development
-
-[Term]
 id: GO:0007277 ! pole cell development
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 
@@ -8536,10 +8081,6 @@
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 
 [Term]
-id: GO:0007281 ! germ cell development
-is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
-
-[Term]
 id: GO:0007282 ! cystoblast division
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 
@@ -8647,10 +8188,6 @@
 is_a: GO:0022414 {is_inferred="true"} ! reproductive process
 
 [Term]
-id: GO:0007320 ! insemination
-is_a: GO:0044703 {is_inferred="true"} ! multi-organism reproductive process
-
-[Term]
 id: GO:0007329 ! positive regulation of transcription from RNA polymerase II promoter by pheromones
 is_a: GO:1901522 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
 
@@ -8711,6 +8248,10 @@
 is_a: GO:0060429 {is_inferred="true"} ! epithelium development
 
 [Term]
+id: GO:0007488 ! histoblast morphogenesis
+is_a: GO:0000902 {is_inferred="true"} ! cell morphogenesis
+
+[Term]
 id: GO:0007503 ! fat body development
 is_a: GO:0060612 {is_inferred="true"} ! adipose tissue development
 
@@ -8781,18 +8322,6 @@
 is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
 
 [Term]
-id: GO:0007611 ! learning or memory
-is_a: GO:0044707 {is_inferred="true"} ! single-multicellular organism process
-
-[Term]
-id: GO:0007617 ! mating behavior
-is_a: GO:0019098 {is_inferred="true"} ! reproductive behavior
-
-[Term]
-id: GO:0008016 ! regulation of heart contraction
-is_a: GO:1903522 {is_inferred="true"} ! regulation of blood circulation
-
-[Term]
 id: GO:0008021 ! synaptic vesicle
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
@@ -8879,11 +8408,6 @@
 is_a: GO:1901681 {is_inferred="true"} ! sulfur compound binding
 
 [Term]
-id: GO:0008202 ! steroid metabolic process
-is_a: GO:0006629 {is_inferred="true"} ! lipid metabolic process
-is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
-
-[Term]
 id: GO:0008203 ! cholesterol metabolic process
 is_a: GO:0016125 {is_inferred="true"} ! sterol metabolic process
 is_a: GO:1902652 {is_inferred="true"} ! secondary alcohol metabolic process
@@ -8901,31 +8425,11 @@
 is_a: GO:1902652 {is_inferred="true"} ! secondary alcohol metabolic process
 
 [Term]
-id: GO:0008206 ! bile acid metabolic process
-is_a: GO:0008202 {is_inferred="true"} ! steroid metabolic process
-is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
-is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
-
-[Term]
-id: GO:0008207 ! C21-steroid hormone metabolic process
-is_a: GO:0008202 {is_inferred="true"} ! steroid metabolic process
-is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
-
-[Term]
 id: GO:0008208 ! C21-steroid hormone catabolic process
 is_a: GO:0006706 {is_inferred="true"} ! steroid catabolic process
 is_a: GO:0008207 {is_inferred="true"} ! C21-steroid hormone metabolic process
 
 [Term]
-id: GO:0008211 ! glucocorticoid metabolic process
-is_a: GO:0008202 {is_inferred="true"} ! steroid metabolic process
-
-[Term]
-id: GO:0008212 ! mineralocorticoid metabolic process
-is_a: GO:0008202 {is_inferred="true"} ! steroid metabolic process
-is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
-
-[Term]
 id: GO:0008215 ! spermine metabolic process
 is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 
@@ -8965,14 +8469,6 @@
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
 [Term]
-id: GO:0008284 ! positive regulation of cell proliferation
-is_a: GO:0042127 {is_inferred="true"} ! regulation of cell proliferation
-
-[Term]
-id: GO:0008285 ! negative regulation of cell proliferation
-is_a: GO:0042127 {is_inferred="true"} ! regulation of cell proliferation
-
-[Term]
 id: GO:0008287 ! protein serine/threonine phosphatase complex
 is_a: GO:1903293 {is_inferred="true"} ! phosphatase complex
 
@@ -9074,10 +8570,6 @@
 is_a: GO:1902554 {is_inferred="true"} ! serine/threonine protein kinase complex
 
 [Term]
-id: GO:0008406 ! gonad development
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-
-[Term]
 id: GO:0008429 ! phosphatidylethanolamine binding
 is_a: GO:0005543 {is_inferred="true"} ! phospholipid binding
 
@@ -9185,12 +8677,6 @@
 is_a: GO:0022402 {is_inferred="true"} ! cell cycle process
 
 [Term]
-id: GO:0008610 ! lipid biosynthetic process
-is_a: GO:0006629 {is_inferred="true"} ! lipid metabolic process
-is_a: GO:0044711 {is_inferred="true"} ! single-organism biosynthetic process
-is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
-
-[Term]
 id: GO:0008611 ! ether lipid biosynthetic process
 is_a: GO:0046485 {is_inferred="true"} ! ether lipid metabolic process
 is_a: GO:0046504 {is_inferred="true"} ! glycerol ether biosynthetic process
@@ -9278,16 +8764,6 @@
 is_a: GO:0019693 {is_inferred="true"} ! ribose phosphate metabolic process
 
 [Term]
-id: GO:0009057 ! macromolecule catabolic process
-is_a: GO:0043170 {is_inferred="true"} ! macromolecule metabolic process
-is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
-
-[Term]
-id: GO:0009059 ! macromolecule biosynthetic process
-is_a: GO:0043170 {is_inferred="true"} ! macromolecule metabolic process
-is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
-
-[Term]
 id: GO:0009062 ! fatty acid catabolic process
 is_a: GO:0006631 {is_inferred="true"} ! fatty acid metabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
@@ -9299,10 +8775,6 @@
 is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
 
 [Term]
-id: GO:0009064 ! glutamine family amino acid metabolic process
-is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
-
-[Term]
 id: GO:0009065 ! glutamine family amino acid catabolic process
 is_a: GO:1901606 {is_inferred="true"} ! alpha-amino acid catabolic process
 
@@ -10170,11 +9642,6 @@
 is_a: GO:1901137 {is_inferred="true"} ! carbohydrate derivative biosynthetic process
 
 [Term]
-id: GO:0009251 ! glucan catabolic process
-is_a: GO:0000272 {is_inferred="true"} ! polysaccharide catabolic process
-is_a: GO:0044042 {is_inferred="true"} ! glucan metabolic process
-
-[Term]
 id: GO:0009252 ! peptidoglycan biosynthetic process
 is_a: GO:0000270 {is_inferred="true"} ! peptidoglycan metabolic process
 is_a: GO:0006024 {is_inferred="true"} ! glycosaminoglycan biosynthetic process
@@ -10281,14 +9748,6 @@
 is_a: GO:0098781 {is_inferred="true"} ! ncRNA transcription
 
 [Term]
-id: GO:0009306 ! protein secretion
-is_a: GO:0015031 {is_inferred="true"} ! protein transport
-
-[Term]
-id: GO:0009308 ! amine metabolic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
-
-[Term]
 id: GO:0009309 ! amine biosynthetic process
 is_a: GO:0009308 {is_inferred="true"} ! amine metabolic process
 is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
@@ -10508,12 +9967,6 @@
 is_a: GO:0090487 {is_inferred="true"} ! secondary metabolite catabolic process
 
 [Term]
-id: GO:0009415 ! response to water
-is_a: GO:0001101 {is_inferred="true"} ! response to acid chemical
-is_a: GO:0010035 {is_inferred="true"} ! response to inorganic substance
-is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
-
-[Term]
 id: GO:0009423 ! chorismate biosynthetic process
 is_a: GO:0043650 {is_inferred="true"} ! dicarboxylic acid biosynthetic process
 is_a: GO:0046417 {is_inferred="true"} ! chorismate metabolic process
@@ -10567,11 +10020,6 @@
 is_a: GO:0009445 {is_inferred="true"} ! putrescine metabolic process
 
 [Term]
-id: GO:0009448 ! gamma-aminobutyric acid metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
-is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
-
-[Term]
 id: GO:0009449 ! gamma-aminobutyric acid biosynthetic process
 is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 is_a: GO:0009448 {is_inferred="true"} ! gamma-aminobutyric acid metabolic process
@@ -10825,10 +10273,6 @@
 is_a: GO:0072522 {is_inferred="true"} ! purine-containing compound biosynthetic process
 
 [Term]
-id: GO:0009712 ! catechol-containing compound metabolic process
-is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
-
-[Term]
 id: GO:0009713 ! catechol-containing compound biosynthetic process
 is_a: GO:0009712 {is_inferred="true"} ! catechol-containing compound metabolic process
 is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
@@ -10952,10 +10396,6 @@
 is_a: GO:1901421 {is_inferred="true"} ! positive regulation of response to alcohol
 
 [Term]
-id: GO:0009790 ! embryo development
-is_a: GO:0007275 {is_inferred="true"} ! multicellular organism development
-
-[Term]
 id: GO:0009793 ! embryo development ending in seed dormancy
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 
@@ -11128,44 +10568,6 @@
 is_a: GO:0044111 {is_inferred="true"} ! development involved in symbiotic interaction
 
 [Term]
-id: GO:0009889 ! regulation of biosynthetic process
-is_a: GO:0019222 {is_inferred="true"} ! regulation of metabolic process
-
-[Term]
-id: GO:0009890 ! negative regulation of biosynthetic process
-is_a: GO:0009889 {is_inferred="true"} ! regulation of biosynthetic process
-is_a: GO:0009892 {is_inferred="true"} ! negative regulation of metabolic process
-
-[Term]
-id: GO:0009891 ! positive regulation of biosynthetic process
-is_a: GO:0009889 {is_inferred="true"} ! regulation of biosynthetic process
-is_a: GO:0009893 {is_inferred="true"} ! positive regulation of metabolic process
-
-[Term]
-id: GO:0009892 ! negative regulation of metabolic process
-is_a: GO:0019222 {is_inferred="true"} ! regulation of metabolic process
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
-
-[Term]
-id: GO:0009893 ! positive regulation of metabolic process
-is_a: GO:0019222 {is_inferred="true"} ! regulation of metabolic process
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
-
-[Term]
-id: GO:0009894 ! regulation of catabolic process
-is_a: GO:0019222 {is_inferred="true"} ! regulation of metabolic process
-
-[Term]
-id: GO:0009895 ! negative regulation of catabolic process
-is_a: GO:0009892 {is_inferred="true"} ! negative regulation of metabolic process
-is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
-
-[Term]
-id: GO:0009896 ! positive regulation of catabolic process
-is_a: GO:0009893 {is_inferred="true"} ! positive regulation of metabolic process
-is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
-
-[Term]
 id: GO:0009897 ! external side of plasma membrane
 is_a: GO:0044459 {is_inferred="true"} ! plasma membrane part
 
@@ -11201,10 +10603,6 @@
 is_a: GO:0072148 {is_inferred="true"} ! epithelial cell fate commitment
 
 [Term]
-id: GO:0009913 ! epidermal cell differentiation
-is_a: GO:0030855 {is_inferred="true"} ! epithelial cell differentiation
-
-[Term]
 id: GO:0009920 ! cell plate formation involved in plant-type cell wall biogenesis
 is_a: GO:0000919 {is_inferred="true"} ! cell plate assembly
 
@@ -11267,22 +10665,6 @@
 is_a: GO:1905392 {is_inferred="true"} ! plant organ morphogenesis
 
 [Term]
-id: GO:0009966 ! regulation of signal transduction
-is_a: GO:0010646 {is_inferred="true"} ! regulation of cell communication
-is_a: GO:0023051 {is_inferred="true"} ! regulation of signaling
-is_a: GO:0048583 {is_inferred="true"} ! regulation of response to stimulus
-
-[Term]
-id: GO:0009967 ! positive regulation of signal transduction
-is_a: GO:0009966 {is_inferred="true"} ! regulation of signal transduction
-is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
-
-[Term]
-id: GO:0009968 ! negative regulation of signal transduction
-is_a: GO:0009966 {is_inferred="true"} ! regulation of signal transduction
-is_a: GO:0048585 {is_inferred="true"} ! negative regulation of response to stimulus
-
-[Term]
 id: GO:0009969 ! xyloglucan biosynthetic process
 is_a: GO:0009250 {is_inferred="true"} ! glucan biosynthetic process
 is_a: GO:0010411 {is_inferred="true"} ! xyloglucan metabolic process
@@ -11384,10 +10766,6 @@
 is_a: GO:0030261 {is_inferred="true"} ! chromosome condensation
 
 [Term]
-id: GO:0010033 ! response to organic substance
-is_a: GO:0042221 {is_inferred="true"} ! response to chemical
-
-[Term]
 id: GO:0010034 ! response to acetate
 is_a: GO:0001101 {is_inferred="true"} ! response to acid chemical
 is_a: GO:0010033 {is_inferred="true"} ! response to organic substance
@@ -11394,10 +10772,6 @@
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
 [Term]
-id: GO:0010035 ! response to inorganic substance
-is_a: GO:0042221 {is_inferred="true"} ! response to chemical
-
-[Term]
 id: GO:0010036 ! response to boron-containing substance
 is_a: GO:0042221 {is_inferred="true"} ! response to chemical
 
@@ -12200,14 +11574,6 @@
 is_a: GO:1901385 {is_inferred="true"} ! regulation of voltage-gated calcium channel activity
 
 [Term]
-id: GO:0010463 ! mesenchymal cell proliferation
-is_a: GO:0008283 {is_inferred="true"} ! cell proliferation
-
-[Term]
-id: GO:0010464 ! regulation of mesenchymal cell proliferation
-is_a: GO:0042127 {is_inferred="true"} ! regulation of cell proliferation
-
-[Term]
 id: GO:0010466 ! negative regulation of peptidase activity
 is_a: GO:0045861 {is_inferred="true"} ! negative regulation of proteolysis
 is_a: GO:0051346 {is_inferred="true"} ! negative regulation of hydrolase activity
@@ -12218,15 +11584,6 @@
 is_a: GO:0060255 {is_inferred="true"} ! regulation of macromolecule metabolic process
 
 [Term]
-id: GO:0010469 ! regulation of receptor activity
-is_a: GO:0065009 {is_inferred="true"} ! regulation of molecular function
-
-[Term]
-id: GO:0010470 ! regulation of gastrulation
-is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
-is_a: GO:0045995 {is_inferred="true"} ! regulation of embryonic development
-
-[Term]
 id: GO:0010477 ! response to sulfur dioxide
 is_a: GO:0010035 {is_inferred="true"} ! response to inorganic substance
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
@@ -12427,23 +11784,6 @@
 is_a: GO:0009743 {is_inferred="true"} ! response to carbohydrate
 
 [Term]
-id: GO:0010556 ! regulation of macromolecule biosynthetic process
-is_a: GO:0009889 {is_inferred="true"} ! regulation of biosynthetic process
-is_a: GO:0060255 {is_inferred="true"} ! regulation of macromolecule metabolic process
-
-[Term]
-id: GO:0010557 ! positive regulation of macromolecule biosynthetic process
-is_a: GO:0009891 {is_inferred="true"} ! positive regulation of biosynthetic process
-is_a: GO:0010556 {is_inferred="true"} ! regulation of macromolecule biosynthetic process
-is_a: GO:0010604 {is_inferred="true"} ! positive regulation of macromolecule metabolic process
-
-[Term]
-id: GO:0010558 ! negative regulation of macromolecule biosynthetic process
-is_a: GO:0009890 {is_inferred="true"} ! negative regulation of biosynthetic process
-is_a: GO:0010556 {is_inferred="true"} ! regulation of macromolecule biosynthetic process
-is_a: GO:0010605 {is_inferred="true"} ! negative regulation of macromolecule metabolic process
-
-[Term]
 id: GO:0010559 ! regulation of glycoprotein biosynthetic process
 is_a: GO:1903018 {is_inferred="true"} ! regulation of glycoprotein metabolic process
 is_a: GO:2000112 {is_inferred="true"} ! regulation of cellular macromolecule biosynthetic process
@@ -12472,19 +11812,6 @@
 is_a: GO:0051174 {is_inferred="true"} ! regulation of phosphorus metabolic process
 
 [Term]
-id: GO:0010564 ! regulation of cell cycle process
-is_a: GO:0051726 {is_inferred="true"} ! regulation of cell cycle
-
-[Term]
-id: GO:0010565 ! regulation of cellular ketone metabolic process
-is_a: GO:0031323 {is_inferred="true"} ! regulation of cellular metabolic process
-
-[Term]
-id: GO:0010566 ! regulation of ketone biosynthetic process
-is_a: GO:0010565 {is_inferred="true"} ! regulation of cellular ketone metabolic process
-is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
-
-[Term]
 id: GO:0010567 ! regulation of ketone catabolic process
 is_a: GO:0010565 {is_inferred="true"} ! regulation of cellular ketone metabolic process
 is_a: GO:0031329 {is_inferred="true"} ! regulation of cellular catabolic process
@@ -12606,16 +11933,6 @@
 is_a: GO:1902115 {is_inferred="true"} ! regulation of organelle assembly
 
 [Term]
-id: GO:0010604 ! positive regulation of macromolecule metabolic process
-is_a: GO:0009893 {is_inferred="true"} ! positive regulation of metabolic process
-is_a: GO:0060255 {is_inferred="true"} ! regulation of macromolecule metabolic process
-
-[Term]
-id: GO:0010605 ! negative regulation of macromolecule metabolic process
-is_a: GO:0009892 {is_inferred="true"} ! negative regulation of metabolic process
-is_a: GO:0060255 {is_inferred="true"} ! regulation of macromolecule metabolic process
-
-[Term]
 id: GO:0010606 ! positive regulation of cytoplasmic mRNA processing body assembly
 is_a: GO:0010603 {is_inferred="true"} ! regulation of cytoplasmic mRNA processing body assembly
 is_a: GO:1902117 {is_inferred="true"} ! positive regulation of organelle assembly
@@ -12726,16 +12043,6 @@
 is_a: GO:0010823 {is_inferred="true"} ! negative regulation of mitochondrion organization
 
 [Term]
-id: GO:0010638 ! positive regulation of organelle organization
-is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
-is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
-
-[Term]
-id: GO:0010639 ! negative regulation of organelle organization
-is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
-is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
-
-[Term]
 id: GO:0010640 ! regulation of platelet-derived growth factor receptor signaling pathway
 is_a: GO:0009966 {is_inferred="true"} ! regulation of signal transduction
 
@@ -12754,20 +12061,6 @@
 is_a: GO:0010646 {is_inferred="true"} ! regulation of cell communication
 
 [Term]
-id: GO:0010646 ! regulation of cell communication
-is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
-
-[Term]
-id: GO:0010647 ! positive regulation of cell communication
-is_a: GO:0010646 {is_inferred="true"} ! regulation of cell communication
-is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
-
-[Term]
-id: GO:0010648 ! negative regulation of cell communication
-is_a: GO:0010646 {is_inferred="true"} ! regulation of cell communication
-is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
-
-[Term]
 id: GO:0010649 ! regulation of cell communication by electrical coupling
 is_a: GO:0010646 {is_inferred="true"} ! regulation of cell communication
 
@@ -12838,23 +12131,6 @@
 is_a: GO:0010665 {is_inferred="true"} ! regulation of cardiac muscle cell apoptotic process
 
 [Term]
-id: GO:0010675 ! regulation of cellular carbohydrate metabolic process
-is_a: GO:0006109 {is_inferred="true"} ! regulation of carbohydrate metabolic process
-is_a: GO:0031323 {is_inferred="true"} ! regulation of cellular metabolic process
-
-[Term]
-id: GO:0010676 ! positive regulation of cellular carbohydrate metabolic process
-is_a: GO:0010675 {is_inferred="true"} ! regulation of cellular carbohydrate metabolic process
-is_a: GO:0031325 {is_inferred="true"} ! positive regulation of cellular metabolic process
-is_a: GO:0045913 {is_inferred="true"} ! positive regulation of carbohydrate metabolic process
-
-[Term]
-id: GO:0010677 ! negative regulation of cellular carbohydrate metabolic process
-is_a: GO:0010675 {is_inferred="true"} ! regulation of cellular carbohydrate metabolic process
-is_a: GO:0031324 {is_inferred="true"} ! negative regulation of cellular metabolic process
-is_a: GO:0045912 {is_inferred="true"} ! negative regulation of carbohydrate metabolic process
-
-[Term]
 id: GO:0010678 ! negative regulation of cellular carbohydrate metabolic process by negative regulation of transcription, DNA-templated
 is_a: GO:0010677 {is_inferred="true"} ! negative regulation of cellular carbohydrate metabolic process
 is_a: GO:0045892 {is_inferred="true"} ! negative regulation of transcription, DNA-templated
@@ -12933,16 +12209,6 @@
 is_a: GO:0007267 {is_inferred="true"} ! cell-cell signaling
 
 [Term]
-id: GO:0010700 ! negative regulation of norepinephrine secretion
-is_a: GO:0014061 {is_inferred="true"} ! regulation of norepinephrine secretion
-is_a: GO:0033604 {is_inferred="true"} ! negative regulation of catecholamine secretion
-
-[Term]
-id: GO:0010701 ! positive regulation of norepinephrine secretion
-is_a: GO:0014061 {is_inferred="true"} ! regulation of norepinephrine secretion
-is_a: GO:0033605 {is_inferred="true"} ! positive regulation of catecholamine secretion
-
-[Term]
 id: GO:0010704 ! meiotic DNA double-strand break processing involved in meiotic gene conversion
 is_a: GO:0000706 {is_inferred="true"} ! meiotic DNA double-strand break processing
 
@@ -13024,14 +12290,6 @@
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 
 [Term]
-id: GO:0010720 ! positive regulation of cell development
-is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
-
-[Term]
-id: GO:0010721 ! negative regulation of cell development
-is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
-
-[Term]
 id: GO:0010722 ! regulation of ferrochelatase activity
 is_a: GO:0051339 {is_inferred="true"} ! regulation of lyase activity
 
@@ -13451,20 +12709,6 @@
 is_a: GO:0060051 {is_inferred="true"} ! negative regulation of protein glycosylation
 
 [Term]
-id: GO:0010837 ! regulation of keratinocyte proliferation
-is_a: GO:0050678 {is_inferred="true"} ! regulation of epithelial cell proliferation
-
-[Term]
-id: GO:0010838 ! positive regulation of keratinocyte proliferation
-is_a: GO:0010837 {is_inferred="true"} ! regulation of keratinocyte proliferation
-is_a: GO:0050679 {is_inferred="true"} ! positive regulation of epithelial cell proliferation
-
-[Term]
-id: GO:0010839 ! negative regulation of keratinocyte proliferation
-is_a: GO:0010837 {is_inferred="true"} ! regulation of keratinocyte proliferation
-is_a: GO:0050680 {is_inferred="true"} ! negative regulation of epithelial cell proliferation
-
-[Term]
 id: GO:0010840 ! regulation of circadian sleep/wake cycle, wakefulness
 is_a: GO:0042749 {is_inferred="true"} ! regulation of circadian sleep/wake cycle
 
@@ -13631,18 +12875,6 @@
 is_a: GO:0010889 {is_inferred="true"} ! regulation of sequestering of triglyceride
 
 [Term]
-id: GO:0010893 ! positive regulation of steroid biosynthetic process
-is_a: GO:0045940 {is_inferred="true"} ! positive regulation of steroid metabolic process
-is_a: GO:0046889 {is_inferred="true"} ! positive regulation of lipid biosynthetic process
-is_a: GO:0050810 {is_inferred="true"} ! regulation of steroid biosynthetic process
-
-[Term]
-id: GO:0010894 ! negative regulation of steroid biosynthetic process
-is_a: GO:0045939 {is_inferred="true"} ! negative regulation of steroid metabolic process
-is_a: GO:0050810 {is_inferred="true"} ! regulation of steroid biosynthetic process
-is_a: GO:0051055 {is_inferred="true"} ! negative regulation of lipid biosynthetic process
-
-[Term]
 id: GO:0010895 ! negative regulation of ergosterol biosynthetic process
 is_a: GO:0010894 {is_inferred="true"} ! negative regulation of steroid biosynthetic process
 is_a: GO:0031327 {is_inferred="true"} ! negative regulation of cellular biosynthetic process
@@ -13712,10 +12944,6 @@
 is_a: GO:0045934 {is_inferred="true"} ! negative regulation of nucleobase-containing compound metabolic process
 
 [Term]
-id: GO:0010907 ! positive regulation of glucose metabolic process
-is_a: GO:0010906 {is_inferred="true"} ! regulation of glucose metabolic process
-
-[Term]
 id: GO:0010908 ! regulation of heparan sulfate proteoglycan biosynthetic process
 is_a: GO:0010559 {is_inferred="true"} ! regulation of glycoprotein biosynthetic process
 is_a: GO:0042762 {is_inferred="true"} ! regulation of sulfur metabolic process
@@ -13867,7 +13095,6 @@
 [Term]
 id: GO:0010948 ! negative regulation of cell cycle process
 is_a: GO:0010564 {is_inferred="true"} ! regulation of cell cycle process
-is_a: GO:0045786 {is_inferred="true"} ! negative regulation of cell cycle
 
 [Term]
 id: GO:0010949 ! negative regulation of intestinal phytosterol absorption
@@ -13927,12 +13154,6 @@
 is_a: GO:0010960 {is_inferred="true"} ! magnesium ion homeostasis
 
 [Term]
-id: GO:0010962 ! regulation of glucan biosynthetic process
-is_a: GO:0010675 {is_inferred="true"} ! regulation of cellular carbohydrate metabolic process
-is_a: GO:0032885 {is_inferred="true"} ! regulation of polysaccharide biosynthetic process
-is_a: GO:2000112 {is_inferred="true"} ! regulation of cellular macromolecule biosynthetic process
-
-[Term]
 id: GO:0010963 ! regulation of L-arginine import
 is_a: GO:0010958 {is_inferred="true"} ! regulation of amino acid import
 
@@ -14285,27 +13506,6 @@
 is_a: GO:0050433 {is_inferred="true"} ! regulation of catecholamine secretion
 
 [Term]
-id: GO:0014061 ! regulation of norepinephrine secretion
-is_a: GO:0050433 {is_inferred="true"} ! regulation of catecholamine secretion
-
-[Term]
-id: GO:0014062 ! regulation of serotonin secretion
-is_a: GO:0043269 {is_inferred="true"} ! regulation of ion transport
-is_a: GO:1903530 {is_inferred="true"} ! regulation of secretion by cell
-
-[Term]
-id: GO:0014063 ! negative regulation of serotonin secretion
-is_a: GO:0014062 {is_inferred="true"} ! regulation of serotonin secretion
-is_a: GO:0043271 {is_inferred="true"} ! negative regulation of ion transport
-is_a: GO:1903531 {is_inferred="true"} ! negative regulation of secretion by cell
-
-[Term]
-id: GO:0014064 ! positive regulation of serotonin secretion
-is_a: GO:0014062 {is_inferred="true"} ! regulation of serotonin secretion
-is_a: GO:0043270 {is_inferred="true"} ! positive regulation of ion transport
-is_a: GO:1903532 {is_inferred="true"} ! positive regulation of secretion by cell
-
-[Term]
 id: GO:0014066 ! regulation of phosphatidylinositol 3-kinase signaling
 is_a: GO:1902531 {is_inferred="true"} ! regulation of intracellular signal transduction
 
@@ -14681,11 +13881,6 @@
 is_a: GO:0044711 {is_inferred="true"} ! single-organism biosynthetic process
 
 [Term]
-id: GO:0015031 ! protein transport
-is_a: GO:0008104 {is_inferred="true"} ! protein localization
-is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
-
-[Term]
 id: GO:0015050 ! methane monooxygenase complex
 is_a: GO:1990204 {is_inferred="true"} ! oxidoreductase complex
 
@@ -15602,11 +14797,6 @@
 is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 
 [Term]
-id: GO:0015696 ! ammonium transport
-is_a: GO:0006812 {is_inferred="true"} ! cation transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
-
-[Term]
 id: GO:0015697 ! quaternary ammonium group transport
 is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
@@ -15669,11 +14859,6 @@
 is_a: GO:0015698 {is_inferred="true"} ! inorganic anion transport
 
 [Term]
-id: GO:0015711 ! organic anion transport
-is_a: GO:0006820 {is_inferred="true"} ! anion transport
-is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
-
-[Term]
 id: GO:0015712 ! hexose phosphate transport
 is_a: GO:0015748 {is_inferred="true"} ! organophosphate ester transport
 is_a: GO:1901264 {is_inferred="true"} ! carbohydrate derivative transport
@@ -15705,10 +14890,6 @@
 is_a: GO:1901264 {is_inferred="true"} ! carbohydrate derivative transport
 
 [Term]
-id: GO:0015718 ! monocarboxylic acid transport
-is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
-
-[Term]
 id: GO:0015719 ! allantoate transport
 is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
 is_a: GO:0042886 {is_inferred="true"} ! amide transport
@@ -15719,11 +14900,6 @@
 is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 
 [Term]
-id: GO:0015721 ! bile acid and bile salt transport
-is_a: GO:0006869 {is_inferred="true"} ! lipid transport
-is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
-
-[Term]
 id: GO:0015722 ! canalicular bile acid transport
 is_a: GO:0032782 {is_inferred="true"} ! bile acid secretion
 
@@ -16184,11 +15360,6 @@
 is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
 
 [Term]
-id: GO:0015833 ! peptide transport
-is_a: GO:0042886 {is_inferred="true"} ! amide transport
-is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
-
-[Term]
 id: GO:0015835 ! peptidoglycan transport
 is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 is_a: GO:1901264 {is_inferred="true"} ! carbohydrate derivative transport
@@ -16198,11 +15369,6 @@
 is_a: GO:0015835 {is_inferred="true"} ! peptidoglycan transport
 
 [Term]
-id: GO:0015837 ! amine transport
-is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
-
-[Term]
 id: GO:0015838 ! amino-acid betaine transport
 is_a: GO:0015697 {is_inferred="true"} ! quaternary ammonium group transport
 
@@ -16233,11 +15399,6 @@
 is_a: GO:0019755 {is_inferred="true"} ! one-carbon compound transport
 
 [Term]
-id: GO:0015844 ! monoamine transport
-is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
-
-[Term]
 id: GO:0015846 ! polyamine transport
 is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
@@ -16253,14 +15414,6 @@
 is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 
 [Term]
-id: GO:0015849 ! organic acid transport
-is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
-
-[Term]
-id: GO:0015850 ! organic hydroxy compound transport
-is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
-
-[Term]
 id: GO:0015851 ! nucleobase transport
 is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
@@ -16357,10 +15510,6 @@
 is_a: GO:0051937 {is_inferred="true"} ! catecholamine transport
 
 [Term]
-id: GO:0015874 ! norepinephrine transport
-is_a: GO:0051937 {is_inferred="true"} ! catecholamine transport
-
-[Term]
 id: GO:0015876 ! acetyl-CoA transport
 is_a: GO:0015916 {is_inferred="true"} ! fatty-acyl-CoA transport
 
@@ -16716,10 +15865,6 @@
 is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
 
 [Term]
-id: GO:0015980 ! energy derivation by oxidation of organic compounds
-is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
-
-[Term]
 id: GO:0015985 ! energy coupled proton transport, down electrochemical gradient
 is_a: GO:1902600 {is_inferred="true"} ! hydrogen ion transmembrane transport
 
@@ -16798,10 +15943,6 @@
 is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
 
 [Term]
-id: GO:0016043 ! cellular component organization
-is_a: GO:0009987 {is_inferred="true"} ! cellular process
-
-[Term]
 id: GO:0016045 ! detection of bacterium
 is_a: GO:0009617 {is_inferred="true"} ! response to bacterium
 is_a: GO:0098543 {is_inferred="true"} ! detection of other organism
@@ -16812,24 +15953,6 @@
 is_a: GO:0098543 {is_inferred="true"} ! detection of other organism
 
 [Term]
-id: GO:0016050 ! vesicle organization
-is_a: GO:0006996 {is_inferred="true"} ! organelle organization
-
-[Term]
-id: GO:0016051 ! carbohydrate biosynthetic process
-is_a: GO:0044711 {is_inferred="true"} ! single-organism biosynthetic process
-is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
-
-[Term]
-id: GO:0016052 ! carbohydrate catabolic process
-is_a: GO:0005975 {is_inferred="true"} ! carbohydrate metabolic process
-is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
-
-[Term]
-id: GO:0016053 ! organic acid biosynthetic process
-is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
-
-[Term]
 id: GO:0016054 ! organic acid catabolic process
 is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
 
@@ -17245,10 +16368,6 @@
 is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
 
 [Term]
-id: GO:0016337 ! single organismal cell-cell adhesion
-is_a: GO:0098609 {is_inferred="true"} ! cell-cell adhesion
-
-[Term]
 id: GO:0016342 ! catenin complex
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
@@ -17332,11 +16451,6 @@
 is_a: GO:0098802 {is_inferred="true"} ! plasma membrane receptor complex
 
 [Term]
-id: GO:0016525 ! negative regulation of angiogenesis
-is_a: GO:0045765 {is_inferred="true"} ! regulation of angiogenesis
-is_a: GO:2000181 {is_inferred="true"} ! negative regulation of blood vessel morphogenesis
-
-[Term]
 id: GO:0016533 ! cyclin-dependent protein kinase 5 holoenzyme complex
 is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
 
@@ -17484,11 +16598,6 @@
 is_a: GO:2000113 {is_inferred="true"} ! negative regulation of cellular macromolecule biosynthetic process
 
 [Term]
-id: GO:0017157 ! regulation of exocytosis
-is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
-is_a: GO:1903530 {is_inferred="true"} ! regulation of secretion by cell
-
-[Term]
 id: GO:0017158 ! regulation of calcium ion-dependent exocytosis
 is_a: GO:1903305 {is_inferred="true"} ! regulation of regulated secretory pathway
 
@@ -17501,10 +16610,6 @@
 is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
 
 [Term]
-id: GO:0018130 ! heterocycle biosynthetic process
-is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
-
-[Term]
 id: GO:0018146 ! keratan sulfate biosynthetic process
 is_a: GO:0006024 {is_inferred="true"} ! glycosaminoglycan biosynthetic process
 is_a: GO:0042339 {is_inferred="true"} ! keratan sulfate metabolic process
@@ -17952,12 +17057,6 @@
 is_a: GO:0042216 {is_inferred="true"} ! phenanthrene catabolic process
 
 [Term]
-id: GO:0018958 ! phenol-containing compound metabolic process
-is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
-is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
-is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
-
-[Term]
 id: GO:0018960 ! 4-nitrophenol metabolic process
 is_a: GO:0006807 {is_inferred="true"} ! nitrogen compound metabolic process
 is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
@@ -18149,18 +17248,10 @@
 is_a: GO:0019208 {is_inferred="true"} ! phosphatase regulator activity
 
 [Term]
-id: GO:0019216 ! regulation of lipid metabolic process
-is_a: GO:0080090 {is_inferred="true"} ! regulation of primary metabolic process
-
-[Term]
 id: GO:0019217 ! regulation of fatty acid metabolic process
 is_a: GO:0019216 {is_inferred="true"} ! regulation of lipid metabolic process
 
 [Term]
-id: GO:0019218 ! regulation of steroid metabolic process
-is_a: GO:0019216 {is_inferred="true"} ! regulation of lipid metabolic process
-
-[Term]
 id: GO:0019219 ! regulation of nucleobase-containing compound metabolic process
 is_a: GO:0031323 {is_inferred="true"} ! regulation of cellular metabolic process
 is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
@@ -18171,10 +17262,6 @@
 is_a: GO:0051174 {is_inferred="true"} ! regulation of phosphorus metabolic process
 
 [Term]
-id: GO:0019222 ! regulation of metabolic process
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-
-[Term]
 id: GO:0019229 ! regulation of vasoconstriction
 is_a: GO:0097746 {is_inferred="true"} ! regulation of blood vessel diameter
 is_a: GO:1903522 {is_inferred="true"} ! regulation of blood circulation
@@ -18464,10 +17551,6 @@
 is_a: GO:0019320 {is_inferred="true"} ! hexose catabolic process
 
 [Term]
-id: GO:0019318 ! hexose metabolic process
-is_a: GO:0005996 {is_inferred="true"} ! monosaccharide metabolic process
-
-[Term]
 id: GO:0019319 ! hexose biosynthetic process
 is_a: GO:0019318 {is_inferred="true"} ! hexose metabolic process
 is_a: GO:0046364 {is_inferred="true"} ! monosaccharide biosynthetic process
@@ -18911,10 +17994,6 @@
 is_a: GO:0019434 {is_inferred="true"} ! sophorosyloxydocosanoate metabolic process
 
 [Term]
-id: GO:0019438 ! aromatic compound biosynthetic process
-is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
-
-[Term]
 id: GO:0019439 ! aromatic compound catabolic process
 is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
 
@@ -19797,10 +18876,6 @@
 is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
 
 [Term]
-id: GO:0019695 ! choline metabolic process
-is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
-
-[Term]
 id: GO:0019697 ! L-xylitol catabolic process to xylulose 5-phosphate
 is_a: GO:0044711 {is_inferred="true"} ! single-organism biosynthetic process
 is_a: GO:0051160 {is_inferred="true"} ! L-xylitol catabolic process
@@ -19872,10 +18947,6 @@
 is_a: GO:0051644 {is_inferred="true"} ! plastid localization
 
 [Term]
-id: GO:0019752 ! carboxylic acid metabolic process
-is_a: GO:0043436 {is_inferred="true"} ! oxoacid metabolic process
-
-[Term]
 id: GO:0019755 ! one-carbon compound transport
 is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 
@@ -20294,11 +19365,6 @@
 is_a: GO:0051961 {is_inferred="true"} ! negative regulation of nervous system development
 
 [Term]
-id: GO:0021915 ! neural tube development
-is_a: GO:0035295 {is_inferred="true"} ! tube development
-is_a: GO:0060429 {is_inferred="true"} ! epithelium development
-
-[Term]
 id: GO:0021918 ! regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment
 is_a: GO:0060850 {is_inferred="true"} ! regulation of transcription involved in cell fate commitment
 
@@ -20390,40 +19456,6 @@
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
 
 [Term]
-id: GO:0022402 ! cell cycle process
-is_a: GO:0009987 {is_inferred="true"} ! cellular process
-
-[Term]
-id: GO:0022407 ! regulation of cell-cell adhesion
-is_a: GO:0030155 {is_inferred="true"} ! regulation of cell adhesion
-
-[Term]
-id: GO:0022408 ! negative regulation of cell-cell adhesion
-is_a: GO:0007162 {is_inferred="true"} ! negative regulation of cell adhesion
-is_a: GO:0022407 {is_inferred="true"} ! regulation of cell-cell adhesion
-
-[Term]
-id: GO:0022409 ! positive regulation of cell-cell adhesion
-is_a: GO:0022407 {is_inferred="true"} ! regulation of cell-cell adhesion
-is_a: GO:0045785 {is_inferred="true"} ! positive regulation of cell adhesion
-
-[Term]
-id: GO:0022412 ! cellular process involved in reproduction in multicellular organism
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-
-[Term]
-id: GO:0022600 ! digestive system process
-is_a: GO:0003008 {is_inferred="true"} ! system process
-
-[Term]
-id: GO:0022602 ! ovulation cycle process
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-
-[Term]
-id: GO:0022603 ! regulation of anatomical structure morphogenesis
-is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
-
-[Term]
 id: GO:0022604 ! regulation of cell morphogenesis
 is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
 is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
@@ -20530,20 +19562,6 @@
 is_a: GO:0032403 {is_inferred="true"} ! protein complex binding
 
 [Term]
-id: GO:0023051 ! regulation of signaling
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-
-[Term]
-id: GO:0023056 ! positive regulation of signaling
-is_a: GO:0023051 {is_inferred="true"} ! regulation of signaling
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
-
-[Term]
-id: GO:0023057 ! negative regulation of signaling
-is_a: GO:0023051 {is_inferred="true"} ! regulation of signaling
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
-
-[Term]
 id: GO:0030001 ! metal ion transport
 is_a: GO:0006812 {is_inferred="true"} ! cation transport
 
@@ -20629,14 +19647,6 @@
 is_a: GO:1902099 {is_inferred="true"} ! regulation of metaphase/anaphase transition of cell cycle
 
 [Term]
-id: GO:0030072 ! peptide hormone secretion
-is_a: GO:0002790 {is_inferred="true"} ! peptide secretion
-
-[Term]
-id: GO:0030073 ! insulin secretion
-is_a: GO:0009306 {is_inferred="true"} ! protein secretion
-
-[Term]
 id: GO:0030085 ! PSII associated light-harvesting complex II, peripheral complex, LHCIIb subcomplex
 is_a: GO:0098807 {is_inferred="true"} ! chloroplast thylakoid membrane protein complex
 
@@ -20671,10 +19681,6 @@
 is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
 
 [Term]
-id: GO:0030104 ! water homeostasis
-is_a: GO:0048878 {is_inferred="true"} ! chemical homeostasis
-
-[Term]
 id: GO:0030111 ! regulation of Wnt signaling pathway
 is_a: GO:0009966 {is_inferred="true"} ! regulation of signal transduction
 
@@ -20733,10 +19739,6 @@
 is_a: GO:0046224 {is_inferred="true"} ! bacteriocin metabolic process
 
 [Term]
-id: GO:0030155 ! regulation of cell adhesion
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-
-[Term]
 id: GO:0030162 ! regulation of proteolysis
 is_a: GO:0051246 {is_inferred="true"} ! regulation of protein metabolic process
 
@@ -20789,37 +19791,6 @@
 is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
-id: GO:0030186 ! melatonin metabolic process
-is_a: GO:0042430 {is_inferred="true"} ! indole-containing compound metabolic process
-is_a: GO:0043603 {is_inferred="true"} ! cellular amide metabolic process
-
-[Term]
-id: GO:0030187 ! melatonin biosynthetic process
-is_a: GO:0030186 {is_inferred="true"} ! melatonin metabolic process
-is_a: GO:0042435 {is_inferred="true"} ! indole-containing compound biosynthetic process
-is_a: GO:0043604 {is_inferred="true"} ! amide biosynthetic process
-
-[Term]
-id: GO:0030193 ! regulation of blood coagulation
-is_a: GO:0050818 {is_inferred="true"} ! regulation of coagulation
-is_a: GO:0061041 {is_inferred="true"} ! regulation of wound healing
-is_a: GO:1900046 {is_inferred="true"} ! regulation of hemostasis
-
-[Term]
-id: GO:0030194 ! positive regulation of blood coagulation
-is_a: GO:0030193 {is_inferred="true"} ! regulation of blood coagulation
-is_a: GO:0050820 {is_inferred="true"} ! positive regulation of coagulation
-is_a: GO:0090303 {is_inferred="true"} ! positive regulation of wound healing
-is_a: GO:1900048 {is_inferred="true"} ! positive regulation of hemostasis
-
-[Term]
-id: GO:0030195 ! negative regulation of blood coagulation
-is_a: GO:0030193 {is_inferred="true"} ! regulation of blood coagulation
-is_a: GO:0050819 {is_inferred="true"} ! negative regulation of coagulation
-is_a: GO:0061045 {is_inferred="true"} ! negative regulation of wound healing
-is_a: GO:1900047 {is_inferred="true"} ! negative regulation of hemostasis
-
-[Term]
 id: GO:0030199 ! collagen fibril organization
 is_a: GO:0071822 {is_inferred="true"} ! protein complex subunit organization
 
@@ -20843,10 +19814,6 @@
 is_a: GO:1903510 {is_inferred="true"} ! mucopolysaccharide metabolic process
 
 [Term]
-id: GO:0030203 ! glycosaminoglycan metabolic process
-is_a: GO:0006022 {is_inferred="true"} ! aminoglycan metabolic process
-
-[Term]
 id: GO:0030204 ! chondroitin sulfate metabolic process
 is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
 is_a: GO:0043436 {is_inferred="true"} ! oxoacid metabolic process
@@ -20961,24 +19928,11 @@
 is_a: GO:0071763 {is_inferred="true"} ! nuclear membrane organization
 
 [Term]
-id: GO:0030278 ! regulation of ossification
-is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
-
-[Term]
-id: GO:0030279 ! negative regulation of ossification
-is_a: GO:0030278 {is_inferred="true"} ! regulation of ossification
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-
-[Term]
 id: GO:0030285 ! integral component of synaptic vesicle membrane
 is_a: GO:0031301 {is_inferred="true"} ! integral component of organelle membrane
 is_a: GO:0098563 {is_inferred="true"} ! intrinsic component of synaptic vesicle membrane
 
 [Term]
-id: GO:0030286 ! dynein complex
-is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
-
-[Term]
 id: GO:0030295 ! protein kinase activator activity
 is_a: GO:0019209 {is_inferred="true"} ! kinase activator activity
 is_a: GO:0019887 {is_inferred="true"} ! protein kinase regulator activity
@@ -21007,18 +19961,6 @@
 is_a: GO:1901264 {is_inferred="true"} ! carbohydrate derivative transport
 
 [Term]
-id: GO:0030307 ! positive regulation of cell growth
-is_a: GO:0001558 {is_inferred="true"} ! regulation of cell growth
-is_a: GO:0045927 {is_inferred="true"} ! positive regulation of growth
-is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
-
-[Term]
-id: GO:0030308 ! negative regulation of cell growth
-is_a: GO:0001558 {is_inferred="true"} ! regulation of cell growth
-is_a: GO:0045926 {is_inferred="true"} ! negative regulation of growth
-is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
-
-[Term]
 id: GO:0030309 ! poly-N-acetyllactosamine metabolic process
 is_a: GO:0006022 {is_inferred="true"} ! aminoglycan metabolic process
 
@@ -21049,20 +19991,6 @@
 is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
 
 [Term]
-id: GO:0030334 ! regulation of cell migration
-is_a: GO:2000145 {is_inferred="true"} ! regulation of cell motility
-
-[Term]
-id: GO:0030335 ! positive regulation of cell migration
-is_a: GO:0030334 {is_inferred="true"} ! regulation of cell migration
-is_a: GO:2000147 {is_inferred="true"} ! positive regulation of cell motility
-
-[Term]
-id: GO:0030336 ! negative regulation of cell migration
-is_a: GO:0030334 {is_inferred="true"} ! regulation of cell migration
-is_a: GO:2000146 {is_inferred="true"} ! negative regulation of cell motility
-
-[Term]
 id: GO:0030381 ! chorion-containing eggshell pattern formation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
@@ -21207,21 +20135,6 @@
 is_a: GO:0030493 {is_inferred="true"} ! bacteriochlorophyll metabolic process
 
 [Term]
-id: GO:0030500 ! regulation of bone mineralization
-is_a: GO:0030278 {is_inferred="true"} ! regulation of ossification
-is_a: GO:0070167 {is_inferred="true"} ! regulation of biomineral tissue development
-
-[Term]
-id: GO:0030501 ! positive regulation of bone mineralization
-is_a: GO:0030500 {is_inferred="true"} ! regulation of bone mineralization
-is_a: GO:0070169 {is_inferred="true"} ! positive regulation of biomineral tissue development
-
-[Term]
-id: GO:0030502 ! negative regulation of bone mineralization
-is_a: GO:0030500 {is_inferred="true"} ! regulation of bone mineralization
-is_a: GO:0070168 {is_inferred="true"} ! negative regulation of biomineral tissue development
-
-[Term]
 id: GO:0030505 ! inorganic diphosphate transport
 is_a: GO:0015698 {is_inferred="true"} ! inorganic anion transport
 
@@ -21843,20 +20756,6 @@
 is_a: GO:0030852 {is_inferred="true"} ! regulation of granulocyte differentiation
 
 [Term]
-id: GO:0030856 ! regulation of epithelial cell differentiation
-is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
-
-[Term]
-id: GO:0030857 ! negative regulation of epithelial cell differentiation
-is_a: GO:0030856 {is_inferred="true"} ! regulation of epithelial cell differentiation
-is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
-
-[Term]
-id: GO:0030858 ! positive regulation of epithelial cell differentiation
-is_a: GO:0030856 {is_inferred="true"} ! regulation of epithelial cell differentiation
-is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
-
-[Term]
 id: GO:0030860 ! regulation of polarized epithelial cell differentiation
 is_a: GO:0030856 {is_inferred="true"} ! regulation of epithelial cell differentiation
 is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
@@ -21917,23 +20816,6 @@
 is_a: GO:0030885 {is_inferred="true"} ! regulation of myeloid dendritic cell activation
 
 [Term]
-id: GO:0030888 ! regulation of B cell proliferation
-is_a: GO:0050670 {is_inferred="true"} ! regulation of lymphocyte proliferation
-is_a: GO:0050864 {is_inferred="true"} ! regulation of B cell activation
-
-[Term]
-id: GO:0030889 ! negative regulation of B cell proliferation
-is_a: GO:0030888 {is_inferred="true"} ! regulation of B cell proliferation
-is_a: GO:0050672 {is_inferred="true"} ! negative regulation of lymphocyte proliferation
-is_a: GO:0050869 {is_inferred="true"} ! negative regulation of B cell activation
-
-[Term]
-id: GO:0030890 ! positive regulation of B cell proliferation
-is_a: GO:0030888 {is_inferred="true"} ! regulation of B cell proliferation
-is_a: GO:0050671 {is_inferred="true"} ! positive regulation of lymphocyte proliferation
-is_a: GO:0050871 {is_inferred="true"} ! positive regulation of B cell activation
-
-[Term]
 id: GO:0030897 ! HOPS complex
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 is_a: GO:0099023 {is_inferred="true"} ! tethering complex
@@ -22097,10 +20979,6 @@
 is_a: GO:0044435 {is_inferred="true"} ! plastid part
 
 [Term]
-id: GO:0031012 ! extracellular matrix
-is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
-
-[Term]
 id: GO:0031017 ! exocrine pancreas development
 is_a: GO:0048732 {is_inferred="true"} ! gland development
 
@@ -22610,57 +21488,6 @@
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
-id: GO:0031323 ! regulation of cellular metabolic process
-is_a: GO:0019222 {is_inferred="true"} ! regulation of metabolic process
-is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
-
-[Term]
-id: GO:0031324 ! negative regulation of cellular metabolic process
-is_a: GO:0009892 {is_inferred="true"} ! negative regulation of metabolic process
-is_a: GO:0031323 {is_inferred="true"} ! regulation of cellular metabolic process
-is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
-
-[Term]
-id: GO:0031325 ! positive regulation of cellular metabolic process
-is_a: GO:0009893 {is_inferred="true"} ! positive regulation of metabolic process
-is_a: GO:0031323 {is_inferred="true"} ! regulation of cellular metabolic process
-is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
-
-[Term]
-id: GO:0031326 ! regulation of cellular biosynthetic process
-is_a: GO:0009889 {is_inferred="true"} ! regulation of biosynthetic process
-is_a: GO:0031323 {is_inferred="true"} ! regulation of cellular metabolic process
-
-[Term]
-id: GO:0031327 ! negative regulation of cellular biosynthetic process
-is_a: GO:0009890 {is_inferred="true"} ! negative regulation of biosynthetic process
-is_a: GO:0031324 {is_inferred="true"} ! negative regulation of cellular metabolic process
-is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
-
-[Term]
-id: GO:0031328 ! positive regulation of cellular biosynthetic process
-is_a: GO:0009891 {is_inferred="true"} ! positive regulation of biosynthetic process
-is_a: GO:0031325 {is_inferred="true"} ! positive regulation of cellular metabolic process
-is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
-
-[Term]
-id: GO:0031329 ! regulation of cellular catabolic process
-is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
-is_a: GO:0031323 {is_inferred="true"} ! regulation of cellular metabolic process
-
-[Term]
-id: GO:0031330 ! negative regulation of cellular catabolic process
-is_a: GO:0009895 {is_inferred="true"} ! negative regulation of catabolic process
-is_a: GO:0031324 {is_inferred="true"} ! negative regulation of cellular metabolic process
-is_a: GO:0031329 {is_inferred="true"} ! regulation of cellular catabolic process
-
-[Term]
-id: GO:0031331 ! positive regulation of cellular catabolic process
-is_a: GO:0009896 {is_inferred="true"} ! positive regulation of catabolic process
-is_a: GO:0031325 {is_inferred="true"} ! positive regulation of cellular metabolic process
-is_a: GO:0031329 {is_inferred="true"} ! regulation of cellular catabolic process
-
-[Term]
 id: GO:0031333 ! negative regulation of protein complex assembly
 is_a: GO:0043254 {is_inferred="true"} ! regulation of protein complex assembly
 is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
@@ -22689,21 +21516,6 @@
 is_a: GO:0051176 {is_inferred="true"} ! positive regulation of sulfur metabolic process
 
 [Term]
-id: GO:0031338 ! regulation of vesicle fusion
-is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
-is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
-
-[Term]
-id: GO:0031339 ! negative regulation of vesicle fusion
-is_a: GO:0010639 {is_inferred="true"} ! negative regulation of organelle organization
-is_a: GO:0031338 {is_inferred="true"} ! regulation of vesicle fusion
-
-[Term]
-id: GO:0031340 ! positive regulation of vesicle fusion
-is_a: GO:0010638 {is_inferred="true"} ! positive regulation of organelle organization
-is_a: GO:0031338 {is_inferred="true"} ! regulation of vesicle fusion
-
-[Term]
 id: GO:0031341 ! regulation of cell killing
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
 
@@ -22732,20 +21544,6 @@
 is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 
 [Term]
-id: GO:0031347 ! regulation of defense response
-is_a: GO:0080134 {is_inferred="true"} ! regulation of response to stress
-
-[Term]
-id: GO:0031348 ! negative regulation of defense response
-is_a: GO:0031347 {is_inferred="true"} ! regulation of defense response
-is_a: GO:0048585 {is_inferred="true"} ! negative regulation of response to stimulus
-
-[Term]
-id: GO:0031349 ! positive regulation of defense response
-is_a: GO:0031347 {is_inferred="true"} ! regulation of defense response
-is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
-
-[Term]
 id: GO:0031350 ! intrinsic component of plastid membrane
 is_a: GO:0031300 {is_inferred="true"} ! intrinsic component of organelle membrane
 is_a: GO:0044435 {is_inferred="true"} ! plastid part
@@ -22881,10 +21679,6 @@
 is_a: GO:0031407 {is_inferred="true"} ! oxylipin metabolic process
 
 [Term]
-id: GO:0031410 ! cytoplasmic vesicle
-is_a: GO:0044444 {is_inferred="true"} ! cytoplasmic part
-
-[Term]
 id: GO:0031418 ! L-ascorbic acid binding
 is_a: GO:0031406 {is_inferred="true"} ! carboxylic acid binding
 is_a: GO:0048029 {is_inferred="true"} ! monosaccharide binding
@@ -23332,20 +22126,6 @@
 is_a: GO:0051962 {is_inferred="true"} ! positive regulation of nervous system development
 
 [Term]
-id: GO:0031644 ! regulation of neurological system process
-is_a: GO:0044057 {is_inferred="true"} ! regulation of system process
-
-[Term]
-id: GO:0031645 ! negative regulation of neurological system process
-is_a: GO:0031644 {is_inferred="true"} ! regulation of neurological system process
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-
-[Term]
-id: GO:0031646 ! positive regulation of neurological system process
-is_a: GO:0031644 {is_inferred="true"} ! regulation of neurological system process
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-
-[Term]
 id: GO:0031650 ! regulation of heat generation
 is_a: GO:0032844 {is_inferred="true"} ! regulation of homeostatic process
 is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
@@ -23563,34 +22343,6 @@
 is_a: GO:0098800 {is_inferred="true"} ! inner mitochondrial membrane protein complex
 
 [Term]
-id: GO:0031943 ! regulation of glucocorticoid metabolic process
-is_a: GO:0019218 {is_inferred="true"} ! regulation of steroid metabolic process
-
-[Term]
-id: GO:0031944 ! negative regulation of glucocorticoid metabolic process
-is_a: GO:0031943 {is_inferred="true"} ! regulation of glucocorticoid metabolic process
-is_a: GO:0045939 {is_inferred="true"} ! negative regulation of steroid metabolic process
-
-[Term]
-id: GO:0031945 ! positive regulation of glucocorticoid metabolic process
-is_a: GO:0031943 {is_inferred="true"} ! regulation of glucocorticoid metabolic process
-is_a: GO:0045940 {is_inferred="true"} ! positive regulation of steroid metabolic process
-
-[Term]
-id: GO:0031946 ! regulation of glucocorticoid biosynthetic process
-is_a: GO:0031943 {is_inferred="true"} ! regulation of glucocorticoid metabolic process
-
-[Term]
-id: GO:0031947 ! negative regulation of glucocorticoid biosynthetic process
-is_a: GO:0031944 {is_inferred="true"} ! negative regulation of glucocorticoid metabolic process
-is_a: GO:0031946 {is_inferred="true"} ! regulation of glucocorticoid biosynthetic process
-
-[Term]
-id: GO:0031948 ! positive regulation of glucocorticoid biosynthetic process
-is_a: GO:0031945 {is_inferred="true"} ! positive regulation of glucocorticoid metabolic process
-is_a: GO:0031946 {is_inferred="true"} ! regulation of glucocorticoid biosynthetic process
-
-[Term]
 id: GO:0031949 ! regulation of glucocorticoid catabolic process
 is_a: GO:0031943 {is_inferred="true"} ! regulation of glucocorticoid metabolic process
 is_a: GO:0050994 {is_inferred="true"} ! regulation of lipid catabolic process
@@ -23640,10 +22392,6 @@
 is_a: GO:0098791 {is_inferred="true"} ! Golgi subcompartment
 
 [Term]
-id: GO:0031987 ! locomotion involved in locomotory behavior
-is_a: GO:0040011 {is_inferred="true"} ! locomotion
-
-[Term]
 id: GO:0031991 ! regulation of actomyosin contractile ring contraction
 is_a: GO:0032954 {is_inferred="true"} ! regulation of cytokinetic process
 
@@ -23719,12 +22467,6 @@
 is_a: GO:0046579 {is_inferred="true"} ! positive regulation of Ras protein signal transduction
 
 [Term]
-id: GO:0032024 ! positive regulation of insulin secretion
-is_a: GO:0050714 {is_inferred="true"} ! positive regulation of protein secretion
-is_a: GO:0050796 {is_inferred="true"} ! regulation of insulin secretion
-is_a: GO:0090277 {is_inferred="true"} ! positive regulation of peptide hormone secretion
-
-[Term]
 id: GO:0032025 ! response to cobalt ion
 is_a: GO:0010038 {is_inferred="true"} ! response to metal ion
 
@@ -23893,20 +22635,6 @@
 is_a: GO:0032109 {is_inferred="true"} ! positive regulation of response to nutrient levels
 
 [Term]
-id: GO:0032101 ! regulation of response to external stimulus
-is_a: GO:0048583 {is_inferred="true"} ! regulation of response to stimulus
-
-[Term]
-id: GO:0032102 ! negative regulation of response to external stimulus
-is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
-is_a: GO:0048585 {is_inferred="true"} ! negative regulation of response to stimulus
-
-[Term]
-id: GO:0032103 ! positive regulation of response to external stimulus
-is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
-is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
-
-[Term]
 id: GO:0032104 ! regulation of response to extracellular stimulus
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
 
@@ -24453,23 +23181,6 @@
 is_a: GO:0006812 {is_inferred="true"} ! cation transport
 
 [Term]
-id: GO:0032330 ! regulation of chondrocyte differentiation
-is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
-is_a: GO:0061035 {is_inferred="true"} ! regulation of cartilage development
-
-[Term]
-id: GO:0032331 ! negative regulation of chondrocyte differentiation
-is_a: GO:0032330 {is_inferred="true"} ! regulation of chondrocyte differentiation
-is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
-is_a: GO:0061037 {is_inferred="true"} ! negative regulation of cartilage development
-
-[Term]
-id: GO:0032332 ! positive regulation of chondrocyte differentiation
-is_a: GO:0032330 {is_inferred="true"} ! regulation of chondrocyte differentiation
-is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
-is_a: GO:0061036 {is_inferred="true"} ! positive regulation of cartilage development
-
-[Term]
 id: GO:0032335 ! regulation of activin secretion
 is_a: GO:0046883 {is_inferred="true"} ! regulation of hormone secretion
 
@@ -24501,23 +23212,6 @@
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 
 [Term]
-id: GO:0032341 ! aldosterone metabolic process
-is_a: GO:0006081 {is_inferred="true"} ! cellular aldehyde metabolic process
-is_a: GO:0008207 {is_inferred="true"} ! C21-steroid hormone metabolic process
-is_a: GO:0008212 {is_inferred="true"} ! mineralocorticoid metabolic process
-is_a: GO:0042180 {is_inferred="true"} ! cellular ketone metabolic process
-is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
-
-[Term]
-id: GO:0032342 ! aldosterone biosynthetic process
-is_a: GO:0006700 {is_inferred="true"} ! C21-steroid hormone biosynthetic process
-is_a: GO:0006705 {is_inferred="true"} ! mineralocorticoid biosynthetic process
-is_a: GO:0032341 {is_inferred="true"} ! aldosterone metabolic process
-is_a: GO:0042181 {is_inferred="true"} ! ketone biosynthetic process
-is_a: GO:0046184 {is_inferred="true"} ! aldehyde biosynthetic process
-is_a: GO:1901617 {is_inferred="true"} ! organic hydroxy compound biosynthetic process
-
-[Term]
 id: GO:0032343 ! aldosterone catabolic process
 is_a: GO:0006712 {is_inferred="true"} ! mineralocorticoid catabolic process
 is_a: GO:0008208 {is_inferred="true"} ! C21-steroid hormone catabolic process
@@ -24527,61 +23221,6 @@
 is_a: GO:1901616 {is_inferred="true"} ! organic hydroxy compound catabolic process
 
 [Term]
-id: GO:0032344 ! regulation of aldosterone metabolic process
-is_a: GO:0010565 {is_inferred="true"} ! regulation of cellular ketone metabolic process
-is_a: GO:0019218 {is_inferred="true"} ! regulation of steroid metabolic process
-is_a: GO:0032350 {is_inferred="true"} ! regulation of hormone metabolic process
-
-[Term]
-id: GO:0032345 ! negative regulation of aldosterone metabolic process
-is_a: GO:0031324 {is_inferred="true"} ! negative regulation of cellular metabolic process
-is_a: GO:0032344 {is_inferred="true"} ! regulation of aldosterone metabolic process
-is_a: GO:0032351 {is_inferred="true"} ! negative regulation of hormone metabolic process
-is_a: GO:0045939 {is_inferred="true"} ! negative regulation of steroid metabolic process
-
-[Term]
-id: GO:0032346 ! positive regulation of aldosterone metabolic process
-is_a: GO:0031325 {is_inferred="true"} ! positive regulation of cellular metabolic process
-is_a: GO:0032344 {is_inferred="true"} ! regulation of aldosterone metabolic process
-is_a: GO:0032352 {is_inferred="true"} ! positive regulation of hormone metabolic process
-is_a: GO:0045940 {is_inferred="true"} ! positive regulation of steroid metabolic process
-
-[Term]
-id: GO:0032347 ! regulation of aldosterone biosynthetic process
-is_a: GO:0010566 {is_inferred="true"} ! regulation of ketone biosynthetic process
-is_a: GO:0032344 {is_inferred="true"} ! regulation of aldosterone metabolic process
-
-[Term]
-id: GO:0032348 ! negative regulation of aldosterone biosynthetic process
-is_a: GO:0032345 {is_inferred="true"} ! negative regulation of aldosterone metabolic process
-is_a: GO:0032347 {is_inferred="true"} ! regulation of aldosterone biosynthetic process
-
-[Term]
-id: GO:0032349 ! positive regulation of aldosterone biosynthetic process
-is_a: GO:0032346 {is_inferred="true"} ! positive regulation of aldosterone metabolic process
-is_a: GO:0032347 {is_inferred="true"} ! regulation of aldosterone biosynthetic process
-
-[Term]
-id: GO:0032350 ! regulation of hormone metabolic process
-is_a: GO:0010817 {is_inferred="true"} ! regulation of hormone levels
-is_a: GO:0019222 {is_inferred="true"} ! regulation of metabolic process
-
-[Term]
-id: GO:0032351 ! negative regulation of hormone metabolic process
-is_a: GO:0009892 {is_inferred="true"} ! negative regulation of metabolic process
-is_a: GO:0032350 {is_inferred="true"} ! regulation of hormone metabolic process
-
-[Term]
-id: GO:0032352 ! positive regulation of hormone metabolic process
-is_a: GO:0009893 {is_inferred="true"} ! positive regulation of metabolic process
-is_a: GO:0032350 {is_inferred="true"} ! regulation of hormone metabolic process
-
-[Term]
-id: GO:0032353 ! negative regulation of hormone biosynthetic process
-is_a: GO:0032351 {is_inferred="true"} ! negative regulation of hormone metabolic process
-is_a: GO:0046885 {is_inferred="true"} ! regulation of hormone biosynthetic process
-
-[Term]
 id: GO:0032355 ! response to estradiol
 is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
 is_a: GO:0033993 {is_inferred="true"} ! response to lipid
@@ -24619,20 +23258,6 @@
 is_a: GO:0032366 {is_inferred="true"} ! intracellular sterol transport
 
 [Term]
-id: GO:0032368 ! regulation of lipid transport
-is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
-
-[Term]
-id: GO:0032369 ! negative regulation of lipid transport
-is_a: GO:0032368 {is_inferred="true"} ! regulation of lipid transport
-is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
-
-[Term]
-id: GO:0032370 ! positive regulation of lipid transport
-is_a: GO:0032368 {is_inferred="true"} ! regulation of lipid transport
-is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
-
-[Term]
 id: GO:0032371 ! regulation of sterol transport
 is_a: GO:0032368 {is_inferred="true"} ! regulation of lipid transport
 
@@ -25840,10 +24465,6 @@
 is_a: GO:0045893 {is_inferred="true"} ! positive regulation of transcription, DNA-templated
 
 [Term]
-id: GO:0032787 ! monocarboxylic acid metabolic process
-is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
-
-[Term]
 id: GO:0032788 ! saturated monocarboxylic acid metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 
@@ -26028,29 +24649,6 @@
 is_a: GO:0048856 {is_inferred="true"} ! anatomical structure development
 
 [Term]
-id: GO:0032838 ! cell projection cytoplasm
-is_a: GO:0099568 {is_inferred="true"} ! cytoplasmic region
-
-[Term]
-id: GO:0032839 ! dendrite cytoplasm
-is_a: GO:0097458 {is_inferred="true"} ! neuron part
-
-[Term]
-id: GO:0032844 ! regulation of homeostatic process
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065008 {is_inferred="true"} ! regulation of biological quality
-
-[Term]
-id: GO:0032845 ! negative regulation of homeostatic process
-is_a: GO:0032844 {is_inferred="true"} ! regulation of homeostatic process
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
-
-[Term]
-id: GO:0032846 ! positive regulation of homeostatic process
-is_a: GO:0032844 {is_inferred="true"} ! regulation of homeostatic process
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
-
-[Term]
 id: GO:0032847 ! regulation of cellular pH reduction
 is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
 is_a: GO:0051453 {is_inferred="true"} ! regulation of intracellular pH
@@ -26120,19 +24718,6 @@
 is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
 
 [Term]
-id: GO:0032879 ! regulation of localization
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-
-[Term]
-id: GO:0032880 ! regulation of protein localization
-is_a: GO:0032879 {is_inferred="true"} ! regulation of localization
-
-[Term]
-id: GO:0032881 ! regulation of polysaccharide metabolic process
-is_a: GO:0006109 {is_inferred="true"} ! regulation of carbohydrate metabolic process
-is_a: GO:0060255 {is_inferred="true"} ! regulation of macromolecule metabolic process
-
-[Term]
 id: GO:0032882 ! regulation of chitin metabolic process
 is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
 
@@ -26149,12 +24734,6 @@
 is_a: GO:2000112 {is_inferred="true"} ! regulation of cellular macromolecule biosynthetic process
 
 [Term]
-id: GO:0032885 ! regulation of polysaccharide biosynthetic process
-is_a: GO:0010556 {is_inferred="true"} ! regulation of macromolecule biosynthetic process
-is_a: GO:0032881 {is_inferred="true"} ! regulation of polysaccharide metabolic process
-is_a: GO:0043255 {is_inferred="true"} ! regulation of carbohydrate biosynthetic process
-
-[Term]
 id: GO:0032886 ! regulation of microtubule-based process
 is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
 
@@ -26174,20 +24753,6 @@
 is_a: GO:0044088 {is_inferred="true"} ! regulation of vacuole organization
 
 [Term]
-id: GO:0032890 ! regulation of organic acid transport
-is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
-
-[Term]
-id: GO:0032891 ! negative regulation of organic acid transport
-is_a: GO:0032890 {is_inferred="true"} ! regulation of organic acid transport
-is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
-
-[Term]
-id: GO:0032892 ! positive regulation of organic acid transport
-is_a: GO:0032890 {is_inferred="true"} ! regulation of organic acid transport
-is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
-
-[Term]
 id: GO:0032893 ! regulation of gluconate transport
 is_a: GO:0032890 {is_inferred="true"} ! regulation of organic acid transport
 is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
@@ -26332,20 +24897,6 @@
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 
 [Term]
-id: GO:0032944 ! regulation of mononuclear cell proliferation
-is_a: GO:0070663 {is_inferred="true"} ! regulation of leukocyte proliferation
-
-[Term]
-id: GO:0032945 ! negative regulation of mononuclear cell proliferation
-is_a: GO:0032944 {is_inferred="true"} ! regulation of mononuclear cell proliferation
-is_a: GO:0070664 {is_inferred="true"} ! negative regulation of leukocyte proliferation
-
-[Term]
-id: GO:0032946 ! positive regulation of mononuclear cell proliferation
-is_a: GO:0032944 {is_inferred="true"} ! regulation of mononuclear cell proliferation
-is_a: GO:0070665 {is_inferred="true"} ! positive regulation of leukocyte proliferation
-
-[Term]
 id: GO:0032948 ! regulation of alpha-glucan metabolic process
 is_a: GO:0010675 {is_inferred="true"} ! regulation of cellular carbohydrate metabolic process
 is_a: GO:0032881 {is_inferred="true"} ! regulation of polysaccharide metabolic process
@@ -26669,10 +25220,6 @@
 is_a: GO:0043065 {is_inferred="true"} ! positive regulation of apoptotic process
 
 [Term]
-id: GO:0033043 ! regulation of organelle organization
-is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
-
-[Term]
 id: GO:0033044 ! regulation of chromosome organization
 is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
 
@@ -27177,23 +25724,6 @@
 is_a: GO:1903322 {is_inferred="true"} ! positive regulation of protein modification by small protein conjugation or removal
 
 [Term]
-id: GO:0033238 ! regulation of cellular amine metabolic process
-is_a: GO:0031323 {is_inferred="true"} ! regulation of cellular metabolic process
-is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
-
-[Term]
-id: GO:0033239 ! negative regulation of cellular amine metabolic process
-is_a: GO:0031324 {is_inferred="true"} ! negative regulation of cellular metabolic process
-is_a: GO:0033238 {is_inferred="true"} ! regulation of cellular amine metabolic process
-is_a: GO:0051172 {is_inferred="true"} ! negative regulation of nitrogen compound metabolic process
-
-[Term]
-id: GO:0033240 ! positive regulation of cellular amine metabolic process
-is_a: GO:0031325 {is_inferred="true"} ! positive regulation of cellular metabolic process
-is_a: GO:0033238 {is_inferred="true"} ! regulation of cellular amine metabolic process
-is_a: GO:0051173 {is_inferred="true"} ! positive regulation of nitrogen compound metabolic process
-
-[Term]
 id: GO:0033242 ! negative regulation of cellular amine catabolic process
 is_a: GO:0033241 {is_inferred="true"} ! regulation of cellular amine catabolic process
 
@@ -27269,11 +25799,6 @@
 is_a: GO:0019829 {is_inferred="true"} ! cation-transporting ATPase activity
 
 [Term]
-id: GO:0033267 ! axon part
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
-is_a: GO:0097458 {is_inferred="true"} ! neuron part
-
-[Term]
 id: GO:0033271 ! myo-inositol phosphate transport
 is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015748 {is_inferred="true"} ! organophosphate ester transport
@@ -27557,11 +26082,11 @@
 
 [Term]
 id: GO:0033370 ! maintenance of protein location in mast cell secretory granule
-is_a: GO:0051651 {is_inferred="true"} ! maintenance of location in cell
+is_a: GO:0032507 {is_inferred="true"} ! maintenance of protein location in cell
 
 [Term]
 id: GO:0033377 ! maintenance of protein location in T cell secretory granule
-is_a: GO:0051651 {is_inferred="true"} ! maintenance of location in cell
+is_a: GO:0032507 {is_inferred="true"} ! maintenance of protein location in cell
 
 [Term]
 id: GO:0033383 ! geranyl diphosphate metabolic process
@@ -28037,16 +26562,6 @@
 is_a: GO:0043270 {is_inferred="true"} ! positive regulation of ion transport
 
 [Term]
-id: GO:0033604 ! negative regulation of catecholamine secretion
-is_a: GO:0050433 {is_inferred="true"} ! regulation of catecholamine secretion
-is_a: GO:1903531 {is_inferred="true"} ! negative regulation of secretion by cell
-
-[Term]
-id: GO:0033605 ! positive regulation of catecholamine secretion
-is_a: GO:0050433 {is_inferred="true"} ! regulation of catecholamine secretion
-is_a: GO:1903532 {is_inferred="true"} ! positive regulation of secretion by cell
-
-[Term]
 id: GO:0033609 ! oxalate metabolic process
 is_a: GO:0043648 {is_inferred="true"} ! dicarboxylic acid metabolic process
 
@@ -28889,23 +27404,6 @@
 is_a: GO:0044429 {is_inferred="true"} ! mitochondrial part
 
 [Term]
-id: GO:0034248 ! regulation of cellular amide metabolic process
-is_a: GO:0031323 {is_inferred="true"} ! regulation of cellular metabolic process
-is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
-
-[Term]
-id: GO:0034249 ! negative regulation of cellular amide metabolic process
-is_a: GO:0031324 {is_inferred="true"} ! negative regulation of cellular metabolic process
-is_a: GO:0034248 {is_inferred="true"} ! regulation of cellular amide metabolic process
-is_a: GO:0051172 {is_inferred="true"} ! negative regulation of nitrogen compound metabolic process
-
-[Term]
-id: GO:0034250 ! positive regulation of cellular amide metabolic process
-is_a: GO:0031325 {is_inferred="true"} ! positive regulation of cellular metabolic process
-is_a: GO:0034248 {is_inferred="true"} ! regulation of cellular amide metabolic process
-is_a: GO:0051173 {is_inferred="true"} ! positive regulation of nitrogen compound metabolic process
-
-[Term]
 id: GO:0034251 ! regulation of cellular amide catabolic process
 is_a: GO:0031329 {is_inferred="true"} ! regulation of cellular catabolic process
 is_a: GO:0034248 {is_inferred="true"} ! regulation of cellular amide metabolic process
@@ -29405,10 +27903,6 @@
 is_a: GO:0042148 {is_inferred="true"} ! strand invasion
 
 [Term]
-id: GO:0034637 ! cellular carbohydrate biosynthetic process
-is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
-
-[Term]
 id: GO:0034638 ! phosphatidylcholine catabolic process
 is_a: GO:0046470 {is_inferred="true"} ! phosphatidylcholine metabolic process
 is_a: GO:0046475 {is_inferred="true"} ! glycerophospholipid catabolic process
@@ -30900,15 +29394,6 @@
 is_a: GO:0051029 {is_inferred="true"} ! rRNA transport
 
 [Term]
-id: GO:0035929 ! steroid hormone secretion
-is_a: GO:0006869 {is_inferred="true"} ! lipid transport
-
-[Term]
-id: GO:0035932 ! aldosterone secretion
-is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
-is_a: GO:0035931 {is_inferred="true"} ! mineralocorticoid secretion
-
-[Term]
 id: GO:0035934 ! corticosterone secretion
 is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
 is_a: GO:0035933 {is_inferred="true"} ! glucocorticoid secretion
@@ -31615,10 +30100,6 @@
 is_a: GO:0046628 {is_inferred="true"} ! positive regulation of insulin receptor signaling pathway
 
 [Term]
-id: GO:0038023 ! signaling receptor activity
-is_a: GO:0004872 {is_inferred="true"} ! receptor activity
-
-[Term]
 id: GO:0038024 ! cargo receptor activity
 is_a: GO:0004872 {is_inferred="true"} ! receptor activity
 
@@ -31893,19 +30374,6 @@
 is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
-id: GO:0040008 ! regulation of growth
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-
-[Term]
-id: GO:0040012 ! regulation of locomotion
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-
-[Term]
-id: GO:0040013 ! negative regulation of locomotion
-is_a: GO:0040012 {is_inferred="true"} ! regulation of locomotion
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
-
-[Term]
 id: GO:0040014 ! regulation of multicellular organism growth
 is_a: GO:0048638 {is_inferred="true"} ! regulation of developmental growth
 is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
@@ -31917,11 +30385,6 @@
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 
 [Term]
-id: GO:0040017 ! positive regulation of locomotion
-is_a: GO:0040012 {is_inferred="true"} ! regulation of locomotion
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
-
-[Term]
 id: GO:0040018 ! positive regulation of multicellular organism growth
 is_a: GO:0040014 {is_inferred="true"} ! regulation of multicellular organism growth
 is_a: GO:0048639 {is_inferred="true"} ! positive regulation of developmental growth
@@ -31928,16 +30391,8 @@
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 
 [Term]
-id: GO:0040019 ! positive regulation of embryonic development
-is_a: GO:0045995 {is_inferred="true"} ! regulation of embryonic development
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-
-[Term]
 id: GO:0040020 ! regulation of meiotic nuclear division
 is_a: GO:0010564 {is_inferred="true"} ! regulation of cell cycle process
-is_a: GO:0051445 {is_inferred="true"} ! regulation of meiotic cell cycle
-is_a: GO:0051783 {is_inferred="true"} ! regulation of nuclear division
 
 [Term]
 id: GO:0040023 ! establishment of nucleus localization
@@ -32083,10 +30538,6 @@
 is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
 
 [Term]
-id: GO:0042110 ! T cell activation
-is_a: GO:0070489 {is_inferred="true"} ! T cell aggregation
-
-[Term]
 id: GO:0042119 ! neutrophil activation
 is_a: GO:0036230 {is_inferred="true"} ! granulocyte activation
 
@@ -32196,16 +30647,6 @@
 is_a: GO:0072525 {is_inferred="true"} ! pyridine-containing compound biosynthetic process
 
 [Term]
-id: GO:0042180 ! cellular ketone metabolic process
-is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
-
-[Term]
-id: GO:0042181 ! ketone biosynthetic process
-is_a: GO:0042180 {is_inferred="true"} ! cellular ketone metabolic process
-is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
-
-[Term]
 id: GO:0042182 ! ketone catabolic process
 is_a: GO:0042180 {is_inferred="true"} ! cellular ketone metabolic process
 is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
@@ -32404,10 +30845,6 @@
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
 [Term]
-id: GO:0042221 ! response to chemical
-is_a: GO:0050896 {is_inferred="true"} ! response to stimulus
-
-[Term]
 id: GO:0042222 ! interleukin-1 biosynthetic process
 is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
 
@@ -32576,21 +31013,10 @@
 is_a: GO:0045187 {is_inferred="true"} ! regulation of circadian sleep/wake cycle, sleep
 
 [Term]
-id: GO:0042321 ! negative regulation of circadian sleep/wake cycle, sleep
-is_a: GO:0042754 {is_inferred="true"} ! negative regulation of circadian rhythm
-is_a: GO:0045187 {is_inferred="true"} ! regulation of circadian sleep/wake cycle, sleep
-is_a: GO:0048521 {is_inferred="true"} ! negative regulation of behavior
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-
-[Term]
 id: GO:0042322 ! negative regulation of circadian sleep/wake cycle, REM sleep
 is_a: GO:0042320 {is_inferred="true"} ! regulation of circadian sleep/wake cycle, REM sleep
 
 [Term]
-id: GO:0042323 ! negative regulation of circadian sleep/wake cycle, non-REM sleep
-is_a: GO:0045188 {is_inferred="true"} ! regulation of circadian sleep/wake cycle, non-REM sleep
-
-[Term]
 id: GO:0042325 ! regulation of phosphorylation
 is_a: GO:0019220 {is_inferred="true"} ! regulation of phosphate metabolic process
 
@@ -32886,13 +31312,6 @@
 is_a: GO:1901162 {is_inferred="true"} ! primary amino compound biosynthetic process
 
 [Term]
-id: GO:0042428 ! serotonin metabolic process
-is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
-is_a: GO:0042430 {is_inferred="true"} ! indole-containing compound metabolic process
-is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
-is_a: GO:1901160 {is_inferred="true"} ! primary amino compound metabolic process
-
-[Term]
 id: GO:0042429 ! serotonin catabolic process
 is_a: GO:0019336 {is_inferred="true"} ! phenol-containing compound catabolic process
 is_a: GO:0042428 {is_inferred="true"} ! serotonin metabolic process
@@ -32900,13 +31319,6 @@
 is_a: GO:1901161 {is_inferred="true"} ! primary amino compound catabolic process
 
 [Term]
-id: GO:0042430 ! indole-containing compound metabolic process
-is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
-is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
-is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
-
-[Term]
 id: GO:0042431 ! indole metabolic process
 is_a: GO:0042430 {is_inferred="true"} ! indole-containing compound metabolic process
 
@@ -32921,14 +31333,6 @@
 is_a: GO:0042436 {is_inferred="true"} ! indole-containing compound catabolic process
 
 [Term]
-id: GO:0042435 ! indole-containing compound biosynthetic process
-is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
-is_a: GO:0019438 {is_inferred="true"} ! aromatic compound biosynthetic process
-is_a: GO:0042430 {is_inferred="true"} ! indole-containing compound metabolic process
-is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
-is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
-
-[Term]
 id: GO:0042436 ! indole-containing compound catabolic process
 is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
 is_a: GO:0042430 {is_inferred="true"} ! indole-containing compound metabolic process
@@ -33476,10 +31880,6 @@
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 
 [Term]
-id: GO:0042701 ! progesterone secretion
-is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
-
-[Term]
 id: GO:0042702 ! uterine wall growth
 is_a: GO:0040007 {is_inferred="true"} ! growth
 
@@ -33563,11 +31963,6 @@
 is_a: GO:0042743 {is_inferred="true"} ! hydrogen peroxide metabolic process
 
 [Term]
-id: GO:0042749 ! regulation of circadian sleep/wake cycle
-is_a: GO:0042752 {is_inferred="true"} ! regulation of circadian rhythm
-is_a: GO:0050795 {is_inferred="true"} ! regulation of behavior
-
-[Term]
 id: GO:0042750 ! hibernation
 is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
@@ -33576,20 +31971,6 @@
 is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
-id: GO:0042752 ! regulation of circadian rhythm
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-
-[Term]
-id: GO:0042753 ! positive regulation of circadian rhythm
-is_a: GO:0042752 {is_inferred="true"} ! regulation of circadian rhythm
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
-
-[Term]
-id: GO:0042754 ! negative regulation of circadian rhythm
-is_a: GO:0042752 {is_inferred="true"} ! regulation of circadian rhythm
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
-
-[Term]
 id: GO:0042758 ! long-chain fatty acid catabolic process
 is_a: GO:0001676 {is_inferred="true"} ! long-chain fatty acid metabolic process
 is_a: GO:0009062 {is_inferred="true"} ! fatty acid catabolic process
@@ -33957,10 +32338,6 @@
 is_a: GO:0042884 {is_inferred="true"} ! microcin transport
 
 [Term]
-id: GO:0042886 ! amide transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
-
-[Term]
 id: GO:0042888 ! molybdenum ion transmembrane transporter activity
 is_a: GO:0046915 {is_inferred="true"} ! transition metal ion transmembrane transporter activity
 
@@ -34518,10 +32895,6 @@
 is_a: GO:0043167 {is_inferred="true"} ! ion binding
 
 [Term]
-id: GO:0043170 ! macromolecule metabolic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
-
-[Term]
 id: GO:0043171 ! peptide catabolic process
 is_a: GO:0006518 {is_inferred="true"} ! peptide metabolic process
 is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
@@ -34595,16 +32968,6 @@
 is_a: GO:0019005 {is_inferred="true"} ! SCF ubiquitin ligase complex
 
 [Term]
-id: GO:0043229 ! intracellular organelle
-is_a: GO:0043226 {is_inferred="true"} ! organelle
-is_a: GO:0044424 {is_inferred="true"} ! intracellular part
-
-[Term]
-id: GO:0043230 ! extracellular organelle
-is_a: GO:0043226 {is_inferred="true"} ! organelle
-is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
-
-[Term]
 id: GO:0043233 ! organelle lumen
 is_a: GO:0031974 {is_inferred="true"} ! membrane-enclosed lumen
 is_a: GO:0044422 {is_inferred="true"} ! organelle part
@@ -34642,11 +33005,6 @@
 is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 
 [Term]
-id: GO:0043255 ! regulation of carbohydrate biosynthetic process
-is_a: GO:0006109 {is_inferred="true"} ! regulation of carbohydrate metabolic process
-is_a: GO:0009889 {is_inferred="true"} ! regulation of biosynthetic process
-
-[Term]
 id: GO:0043266 ! regulation of potassium ion transport
 is_a: GO:0010959 {is_inferred="true"} ! regulation of metal ion transport
 
@@ -34661,20 +33019,6 @@
 is_a: GO:0043270 {is_inferred="true"} ! positive regulation of ion transport
 
 [Term]
-id: GO:0043269 ! regulation of ion transport
-is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
-
-[Term]
-id: GO:0043270 ! positive regulation of ion transport
-is_a: GO:0043269 {is_inferred="true"} ! regulation of ion transport
-is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
-
-[Term]
-id: GO:0043271 ! negative regulation of ion transport
-is_a: GO:0043269 {is_inferred="true"} ! regulation of ion transport
-is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
-
-[Term]
 id: GO:0043272 ! ethylene biosynthesis involved in jasmonic acid and ethylene-dependent systemic resistance
 is_a: GO:0009693 {is_inferred="true"} ! ethylene biosynthetic process
 
@@ -34733,8 +33077,13 @@
 is_a: GO:0007043 {is_inferred="true"} ! cell-cell junction assembly
 
 [Term]
+id: GO:0043299 ! leukocyte degranulation
+is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
+
+[Term]
 id: GO:0043300 ! regulation of leukocyte degranulation
 is_a: GO:0002697 {is_inferred="true"} ! regulation of immune effector process
+is_a: GO:0060341 {is_inferred="true"} ! regulation of cellular localization
 is_a: GO:1903305 {is_inferred="true"} ! regulation of regulated secretory pathway
 
 [Term]
@@ -35203,20 +33552,6 @@
 is_a: GO:0043467 {is_inferred="true"} ! regulation of generation of precursor metabolites and energy
 
 [Term]
-id: GO:0043467 ! regulation of generation of precursor metabolites and energy
-is_a: GO:0031323 {is_inferred="true"} ! regulation of cellular metabolic process
-
-[Term]
-id: GO:0043470 ! regulation of carbohydrate catabolic process
-is_a: GO:0006109 {is_inferred="true"} ! regulation of carbohydrate metabolic process
-is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
-
-[Term]
-id: GO:0043471 ! regulation of cellular carbohydrate catabolic process
-is_a: GO:0010675 {is_inferred="true"} ! regulation of cellular carbohydrate metabolic process
-is_a: GO:0043470 {is_inferred="true"} ! regulation of carbohydrate catabolic process
-
-[Term]
 id: GO:0043474 ! pigment metabolic process involved in pigmentation
 is_a: GO:0042440 {is_inferred="true"} ! pigment metabolic process
 
@@ -35446,10 +33781,6 @@
 is_a: GO:0006810 {is_inferred="true"} ! transport
 
 [Term]
-id: GO:0043576 ! regulation of respiratory gaseous exchange
-is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
-
-[Term]
 id: GO:0043579 ! elaioplast organization
 is_a: GO:0009657 {is_inferred="true"} ! plastid organization
 
@@ -35509,10 +33840,6 @@
 is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
 
 [Term]
-id: GO:0043604 ! amide biosynthetic process
-is_a: GO:0043603 {is_inferred="true"} ! cellular amide metabolic process
-
-[Term]
 id: GO:0043606 ! formamide metabolic process
 is_a: GO:0043603 {is_inferred="true"} ! cellular amide metabolic process
 is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
@@ -35553,10 +33880,6 @@
 is_a: GO:0046247 {is_inferred="true"} ! terpene catabolic process
 
 [Term]
-id: GO:0043616 ! keratinocyte proliferation
-is_a: GO:0050673 {is_inferred="true"} ! epithelial cell proliferation
-
-[Term]
 id: GO:0043622 ! cortical microtubule organization
 is_a: GO:0031122 {is_inferred="true"} ! cytoplasmic microtubule organization
 
@@ -35642,10 +33965,6 @@
 is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
 
 [Term]
-id: GO:0043648 ! dicarboxylic acid metabolic process
-is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
-
-[Term]
 id: GO:0043649 ! dicarboxylic acid catabolic process
 is_a: GO:0043648 {is_inferred="true"} ! dicarboxylic acid metabolic process
 is_a: GO:0046395 {is_inferred="true"} ! carboxylic acid catabolic process
@@ -35749,20 +34068,6 @@
 is_a: GO:0015081 {is_inferred="true"} ! sodium ion transmembrane transporter activity
 
 [Term]
-id: GO:0043900 ! regulation of multi-organism process
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-
-[Term]
-id: GO:0043901 ! negative regulation of multi-organism process
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
-
-[Term]
-id: GO:0043902 ! positive regulation of multi-organism process
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
-
-[Term]
 id: GO:0043903 ! regulation of symbiosis, encompassing mutualism through parasitism
 is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 
@@ -35897,35 +34202,6 @@
 is_a: GO:0044035 {is_inferred="true"} ! multi-organism catabolic process
 
 [Term]
-id: GO:0044042 ! glucan metabolic process
-is_a: GO:0005976 {is_inferred="true"} ! polysaccharide metabolic process
-
-[Term]
-id: GO:0044057 ! regulation of system process
-is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
-
-[Term]
-id: GO:0044058 ! regulation of digestive system process
-is_a: GO:0044057 {is_inferred="true"} ! regulation of system process
-
-[Term]
-id: GO:0044060 ! regulation of endocrine process
-is_a: GO:0044057 {is_inferred="true"} ! regulation of system process
-
-[Term]
-id: GO:0044062 ! regulation of excretion
-is_a: GO:0044057 {is_inferred="true"} ! regulation of system process
-
-[Term]
-id: GO:0044065 ! regulation of respiratory system process
-is_a: GO:0043576 {is_inferred="true"} ! regulation of respiratory gaseous exchange
-is_a: GO:0044057 {is_inferred="true"} ! regulation of system process
-
-[Term]
-id: GO:0044070 ! regulation of anion transport
-is_a: GO:0043269 {is_inferred="true"} ! regulation of ion transport
-
-[Term]
 id: GO:0044088 ! regulation of vacuole organization
 is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
 
@@ -35944,14 +34220,6 @@
 is_a: GO:0044085 {is_inferred="true"} ! cellular component biogenesis
 
 [Term]
-id: GO:0044092 ! negative regulation of molecular function
-is_a: GO:0065009 {is_inferred="true"} ! regulation of molecular function
-
-[Term]
-id: GO:0044093 ! positive regulation of molecular function
-is_a: GO:0065009 {is_inferred="true"} ! regulation of molecular function
-
-[Term]
 id: GO:0044107 ! cellular alcohol metabolic process
 is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
 
@@ -36190,30 +34458,10 @@
 is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 
 [Term]
-id: GO:0044420 ! extracellular matrix component
-is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
-
-[Term]
-id: GO:0044421 ! extracellular region part
-is_a: GO:0005575 {is_inferred="true"} ! cellular_component
-
-[Term]
-id: GO:0044422 ! organelle part
-is_a: GO:0005575 {is_inferred="true"} ! cellular_component
-
-[Term]
 id: GO:0044423 ! virion part
 is_a: GO:0005575 {is_inferred="true"} ! cellular_component
 
 [Term]
-id: GO:0044424 ! intracellular part
-is_a: GO:0044464 {is_inferred="true"} ! cell part
-
-[Term]
-id: GO:0044425 ! membrane part
-is_a: GO:0005575 {is_inferred="true"} ! cellular_component
-
-[Term]
 id: GO:0044426 ! cell wall part
 is_a: GO:0044462 {is_inferred="true"} ! external encapsulating structure part
 
@@ -36230,10 +34478,6 @@
 is_a: GO:0044444 {is_inferred="true"} ! cytoplasmic part
 
 [Term]
-id: GO:0044433 ! cytoplasmic vesicle part
-is_a: GO:0044444 {is_inferred="true"} ! cytoplasmic part
-
-[Term]
 id: GO:0044434 ! chloroplast part
 is_a: GO:0044435 {is_inferred="true"} ! plastid part
 
@@ -36262,36 +34506,18 @@
 is_a: GO:0044433 {is_inferred="true"} ! cytoplasmic vesicle part
 
 [Term]
-id: GO:0044441 ! ciliary part
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
-
-[Term]
 id: GO:0044443 ! pilus part
 is_a: GO:0044463 {is_inferred="true"} ! cell projection part
 
 [Term]
-id: GO:0044444 ! cytoplasmic part
-is_a: GO:0044424 {is_inferred="true"} ! intracellular part
-
-[Term]
 id: GO:0044445 ! cytosolic part
 is_a: GO:0044444 {is_inferred="true"} ! cytoplasmic part
 
 [Term]
-id: GO:0044447 ! axoneme part
-is_a: GO:0044430 {is_inferred="true"} ! cytoskeletal part
-is_a: GO:0044441 {is_inferred="true"} ! ciliary part
-
-[Term]
 id: GO:0044448 ! cell cortex part
 is_a: GO:0044444 {is_inferred="true"} ! cytoplasmic part
 
 [Term]
-id: GO:0044449 ! contractile fiber part
-is_a: GO:0044422 {is_inferred="true"} ! organelle part
-is_a: GO:0044444 {is_inferred="true"} ! cytoplasmic part
-
-[Term]
 id: GO:0044450 ! microtubule organizing center part
 is_a: GO:0044430 {is_inferred="true"} ! cytoskeletal part
 
@@ -36331,11 +34557,6 @@
 is_a: GO:0060271 {is_inferred="true"} ! cilium assembly
 
 [Term]
-id: GO:0044459 ! plasma membrane part
-is_a: GO:0044425 {is_inferred="true"} ! membrane part
-is_a: GO:0044464 {is_inferred="true"} ! cell part
-
-[Term]
 id: GO:0044461 ! bacterial-type flagellum part
 is_a: GO:0044422 {is_inferred="true"} ! organelle part
 
@@ -36344,14 +34565,6 @@
 is_a: GO:0044464 {is_inferred="true"} ! cell part
 
 [Term]
-id: GO:0044463 ! cell projection part
-is_a: GO:0044464 {is_inferred="true"} ! cell part
-
-[Term]
-id: GO:0044464 ! cell part
-is_a: GO:0005575 {is_inferred="true"} ! cellular_component
-
-[Term]
 id: GO:0044477 ! envenomation resulting in negative regulation of platelet aggregation in other organism
 is_a: GO:0044365 {is_inferred="true"} ! envenomation resulting in modulation of platelet aggregation in other organism
 
@@ -36476,22 +34689,6 @@
 is_a: GO:0044111 {is_inferred="true"} ! development involved in symbiotic interaction
 
 [Term]
-id: GO:0044703 ! multi-organism reproductive process
-is_a: GO:0051704 {is_inferred="true"} ! multi-organism process
-
-[Term]
-id: GO:0044710 ! single-organism metabolic process
-is_a: GO:0044699 {is_inferred="true"} ! single-organism process
-
-[Term]
-id: GO:0044723 ! single-organism carbohydrate metabolic process
-is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
-
-[Term]
-id: GO:0044724 ! single-organism carbohydrate catabolic process
-is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
-
-[Term]
 id: GO:0044731 ! Ost-alpha/Ost-beta complex
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
@@ -36537,10 +34734,6 @@
 is_a: GO:0051704 {is_inferred="true"} ! multi-organism process
 
 [Term]
-id: GO:0044765 ! single-organism transport
-is_a: GO:1902578 {is_inferred="true"} ! single-organism localization
-
-[Term]
 id: GO:0044766 ! multi-organism transport
 is_a: GO:1902579 {is_inferred="true"} ! multi-organism localization
 
@@ -36599,10 +34792,6 @@
 is_a: GO:0098803 {is_inferred="true"} ! respiratory chain complex
 
 [Term]
-id: GO:0044802 ! single-organism membrane organization
-is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
-
-[Term]
 id: GO:0044803 ! multi-organism membrane organization
 is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
 
@@ -36966,14 +35155,6 @@
 is_a: GO:0034333 {is_inferred="true"} ! adherens junction assembly
 
 [Term]
-id: GO:0045187 ! regulation of circadian sleep/wake cycle, sleep
-is_a: GO:0042749 {is_inferred="true"} ! regulation of circadian sleep/wake cycle
-
-[Term]
-id: GO:0045188 ! regulation of circadian sleep/wake cycle, non-REM sleep
-is_a: GO:0045187 {is_inferred="true"} ! regulation of circadian sleep/wake cycle, sleep
-
-[Term]
 id: GO:0045189 ! connective tissue growth factor biosynthetic process
 is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
 
@@ -38026,40 +36207,6 @@
 is_a: GO:0036230 {is_inferred="true"} ! granulocyte activation
 
 [Term]
-id: GO:0045577 ! regulation of B cell differentiation
-is_a: GO:0045619 {is_inferred="true"} ! regulation of lymphocyte differentiation
-is_a: GO:0050864 {is_inferred="true"} ! regulation of B cell activation
-
-[Term]
-id: GO:0045578 ! negative regulation of B cell differentiation
-is_a: GO:0045577 {is_inferred="true"} ! regulation of B cell differentiation
-is_a: GO:0045620 {is_inferred="true"} ! negative regulation of lymphocyte differentiation
-is_a: GO:0050869 {is_inferred="true"} ! negative regulation of B cell activation
-
-[Term]
-id: GO:0045579 ! positive regulation of B cell differentiation
-is_a: GO:0045577 {is_inferred="true"} ! regulation of B cell differentiation
-is_a: GO:0045621 {is_inferred="true"} ! positive regulation of lymphocyte differentiation
-is_a: GO:0050871 {is_inferred="true"} ! positive regulation of B cell activation
-
-[Term]
-id: GO:0045580 ! regulation of T cell differentiation
-is_a: GO:0045619 {is_inferred="true"} ! regulation of lymphocyte differentiation
-is_a: GO:0050863 {is_inferred="true"} ! regulation of T cell activation
-
-[Term]
-id: GO:0045581 ! negative regulation of T cell differentiation
-is_a: GO:0045580 {is_inferred="true"} ! regulation of T cell differentiation
-is_a: GO:0045620 {is_inferred="true"} ! negative regulation of lymphocyte differentiation
-is_a: GO:0050868 {is_inferred="true"} ! negative regulation of T cell activation
-
-[Term]
-id: GO:0045582 ! positive regulation of T cell differentiation
-is_a: GO:0045580 {is_inferred="true"} ! regulation of T cell differentiation
-is_a: GO:0045621 {is_inferred="true"} ! positive regulation of lymphocyte differentiation
-is_a: GO:0050870 {is_inferred="true"} ! positive regulation of T cell activation
-
-[Term]
 id: GO:0045583 ! regulation of cytotoxic T cell differentiation
 is_a: GO:0045580 {is_inferred="true"} ! regulation of T cell differentiation
 
@@ -38129,23 +36276,6 @@
 is_a: GO:2000388 {is_inferred="true"} ! positive regulation of antral ovarian follicle growth
 
 [Term]
-id: GO:0045595 ! regulation of cell differentiation
-is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
-is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
-
-[Term]
-id: GO:0045596 ! negative regulation of cell differentiation
-is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
-is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
-
-[Term]
-id: GO:0045597 ! positive regulation of cell differentiation
-is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
-is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
-
-[Term]
 id: GO:0045598 ! regulation of fat cell differentiation
 is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
 
@@ -38174,21 +36304,6 @@
 is_a: GO:0045601 {is_inferred="true"} ! regulation of endothelial cell differentiation
 
 [Term]
-id: GO:0045604 ! regulation of epidermal cell differentiation
-is_a: GO:0030856 {is_inferred="true"} ! regulation of epithelial cell differentiation
-is_a: GO:0045682 {is_inferred="true"} ! regulation of epidermis development
-
-[Term]
-id: GO:0045605 ! negative regulation of epidermal cell differentiation
-is_a: GO:0030857 {is_inferred="true"} ! negative regulation of epithelial cell differentiation
-is_a: GO:0045604 {is_inferred="true"} ! regulation of epidermal cell differentiation
-
-[Term]
-id: GO:0045606 ! positive regulation of epidermal cell differentiation
-is_a: GO:0030858 {is_inferred="true"} ! positive regulation of epithelial cell differentiation
-is_a: GO:0045604 {is_inferred="true"} ! regulation of epidermal cell differentiation
-
-[Term]
 id: GO:0045607 ! regulation of auditory receptor cell differentiation
 is_a: GO:0045604 {is_inferred="true"} ! regulation of epidermal cell differentiation
 is_a: GO:2000980 {is_inferred="true"} ! regulation of inner ear receptor cell differentiation
@@ -38239,37 +36354,6 @@
 is_a: GO:0045613 {is_inferred="true"} ! regulation of plasmatocyte differentiation
 
 [Term]
-id: GO:0045616 ! regulation of keratinocyte differentiation
-is_a: GO:0045604 {is_inferred="true"} ! regulation of epidermal cell differentiation
-
-[Term]
-id: GO:0045617 ! negative regulation of keratinocyte differentiation
-is_a: GO:0045605 {is_inferred="true"} ! negative regulation of epidermal cell differentiation
-is_a: GO:0045616 {is_inferred="true"} ! regulation of keratinocyte differentiation
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-
-[Term]
-id: GO:0045618 ! positive regulation of keratinocyte differentiation
-is_a: GO:0045606 {is_inferred="true"} ! positive regulation of epidermal cell differentiation
-is_a: GO:0045616 {is_inferred="true"} ! regulation of keratinocyte differentiation
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-
-[Term]
-id: GO:0045619 ! regulation of lymphocyte differentiation
-is_a: GO:1902105 {is_inferred="true"} ! regulation of leukocyte differentiation
-
-[Term]
-id: GO:0045620 ! negative regulation of lymphocyte differentiation
-is_a: GO:0045619 {is_inferred="true"} ! regulation of lymphocyte differentiation
-is_a: GO:0051250 {is_inferred="true"} ! negative regulation of lymphocyte activation
-is_a: GO:1902106 {is_inferred="true"} ! negative regulation of leukocyte differentiation
-
-[Term]
-id: GO:0045621 ! positive regulation of lymphocyte differentiation
-is_a: GO:0051251 {is_inferred="true"} ! positive regulation of lymphocyte activation
-is_a: GO:1902107 {is_inferred="true"} ! positive regulation of leukocyte differentiation
-
-[Term]
 id: GO:0045622 ! regulation of T-helper cell differentiation
 is_a: GO:0002697 {is_inferred="true"} ! regulation of immune effector process
 is_a: GO:0043370 {is_inferred="true"} ! regulation of CD4-positive, alpha-beta T cell differentiation
@@ -38562,20 +36646,6 @@
 is_a: GO:0046534 {is_inferred="true"} ! positive regulation of photoreceptor cell differentiation
 
 [Term]
-id: GO:0045682 ! regulation of epidermis development
-is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
-
-[Term]
-id: GO:0045683 ! negative regulation of epidermis development
-is_a: GO:0045682 {is_inferred="true"} ! regulation of epidermis development
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
-
-[Term]
-id: GO:0045684 ! positive regulation of epidermis development
-is_a: GO:0045682 {is_inferred="true"} ! regulation of epidermis development
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
-
-[Term]
 id: GO:0045685 ! regulation of glial cell differentiation
 is_a: GO:0014013 {is_inferred="true"} ! regulation of gliogenesis
 
@@ -38759,12 +36829,6 @@
 is_a: GO:0051055 {is_inferred="true"} ! negative regulation of lipid biosynthetic process
 
 [Term]
-id: GO:0045719 ! negative regulation of glycogen biosynthetic process
-is_a: GO:0005979 {is_inferred="true"} ! regulation of glycogen biosynthetic process
-is_a: GO:0070874 {is_inferred="true"} ! negative regulation of glycogen metabolic process
-is_a: GO:2000113 {is_inferred="true"} ! negative regulation of cellular macromolecule biosynthetic process
-
-[Term]
 id: GO:0045720 ! negative regulation of integrin biosynthetic process
 is_a: GO:0010558 {is_inferred="true"} ! negative regulation of macromolecule biosynthetic process
 is_a: GO:0045113 {is_inferred="true"} ! regulation of integrin biosynthetic process
@@ -38792,13 +36856,6 @@
 is_a: GO:1902117 {is_inferred="true"} ! positive regulation of organelle assembly
 
 [Term]
-id: GO:0045725 ! positive regulation of glycogen biosynthetic process
-is_a: GO:0005979 {is_inferred="true"} ! regulation of glycogen biosynthetic process
-is_a: GO:0010557 {is_inferred="true"} ! positive regulation of macromolecule biosynthetic process
-is_a: GO:0031328 {is_inferred="true"} ! positive regulation of cellular biosynthetic process
-is_a: GO:0070875 {is_inferred="true"} ! positive regulation of glycogen metabolic process
-
-[Term]
 id: GO:0045726 ! positive regulation of integrin biosynthetic process
 is_a: GO:0010557 {is_inferred="true"} ! positive regulation of macromolecule biosynthetic process
 is_a: GO:0045113 {is_inferred="true"} ! regulation of integrin biosynthetic process
@@ -38950,24 +37007,6 @@
 is_a: GO:0051349 {is_inferred="true"} ! positive regulation of lyase activity
 
 [Term]
-id: GO:0045763 ! negative regulation of cellular amino acid metabolic process
-is_a: GO:0006521 {is_inferred="true"} ! regulation of cellular amino acid metabolic process
-
-[Term]
-id: GO:0045764 ! positive regulation of cellular amino acid metabolic process
-is_a: GO:0006521 {is_inferred="true"} ! regulation of cellular amino acid metabolic process
-
-[Term]
-id: GO:0045765 ! regulation of angiogenesis
-is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
-is_a: GO:1901342 {is_inferred="true"} ! regulation of vasculature development
-
-[Term]
-id: GO:0045766 ! positive regulation of angiogenesis
-is_a: GO:0045765 {is_inferred="true"} ! regulation of angiogenesis
-is_a: GO:1904018 {is_inferred="true"} ! positive regulation of vasculature development
-
-[Term]
 id: GO:0045769 ! negative regulation of asymmetric cell division
 is_a: GO:0009786 {is_inferred="true"} ! regulation of asymmetric cell division
 is_a: GO:0051782 {is_inferred="true"} ! negative regulation of cell division
@@ -38994,11 +37033,6 @@
 is_a: GO:0045726 {is_inferred="true"} ! positive regulation of integrin biosynthetic process
 
 [Term]
-id: GO:0045778 ! positive regulation of ossification
-is_a: GO:0030278 {is_inferred="true"} ! regulation of ossification
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-
-[Term]
 id: GO:0045779 ! negative regulation of bone resorption
 is_a: GO:0032845 {is_inferred="true"} ! negative regulation of homeostatic process
 is_a: GO:0045124 {is_inferred="true"} ! regulation of bone resorption
@@ -39021,21 +37055,6 @@
 is_a: GO:1903666 {is_inferred="true"} ! positive regulation of asexual reproduction
 
 [Term]
-id: GO:0045785 ! positive regulation of cell adhesion
-is_a: GO:0030155 {is_inferred="true"} ! regulation of cell adhesion
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
-
-[Term]
-id: GO:0045786 ! negative regulation of cell cycle
-is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
-is_a: GO:0051726 {is_inferred="true"} ! regulation of cell cycle
-
-[Term]
-id: GO:0045787 ! positive regulation of cell cycle
-is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
-is_a: GO:0051726 {is_inferred="true"} ! regulation of cell cycle
-
-[Term]
 id: GO:0045796 ! negative regulation of intestinal cholesterol absorption
 is_a: GO:0030300 {is_inferred="true"} ! regulation of intestinal cholesterol absorption
 is_a: GO:0032375 {is_inferred="true"} ! negative regulation of cholesterol transport
@@ -39116,16 +37135,6 @@
 is_a: GO:2000052 {is_inferred="true"} ! positive regulation of non-canonical Wnt signaling pathway
 
 [Term]
-id: GO:0045818 ! negative regulation of glycogen catabolic process
-is_a: GO:0005981 {is_inferred="true"} ! regulation of glycogen catabolic process
-is_a: GO:0070874 {is_inferred="true"} ! negative regulation of glycogen metabolic process
-
-[Term]
-id: GO:0045819 ! positive regulation of glycogen catabolic process
-is_a: GO:0005981 {is_inferred="true"} ! regulation of glycogen catabolic process
-is_a: GO:0070875 {is_inferred="true"} ! positive regulation of glycogen metabolic process
-
-[Term]
 id: GO:0045820 ! negative regulation of glycolytic process
 is_a: GO:0006110 {is_inferred="true"} ! regulation of glycolytic process
 is_a: GO:0009895 {is_inferred="true"} ! negative regulation of catabolic process
@@ -39142,16 +37151,6 @@
 is_a: GO:1903580 {is_inferred="true"} ! positive regulation of ATP metabolic process
 
 [Term]
-id: GO:0045822 ! negative regulation of heart contraction
-is_a: GO:0008016 {is_inferred="true"} ! regulation of heart contraction
-is_a: GO:1903523 {is_inferred="true"} ! negative regulation of blood circulation
-
-[Term]
-id: GO:0045823 ! positive regulation of heart contraction
-is_a: GO:0008016 {is_inferred="true"} ! regulation of heart contraction
-is_a: GO:1903524 {is_inferred="true"} ! positive regulation of blood circulation
-
-[Term]
 id: GO:0045824 ! negative regulation of innate immune response
 is_a: GO:0031348 {is_inferred="true"} ! negative regulation of defense response
 is_a: GO:0045088 {is_inferred="true"} ! regulation of innate immune response
@@ -39200,27 +37199,11 @@
 is_a: GO:0032414 {is_inferred="true"} ! positive regulation of ion transmembrane transporter activity
 
 [Term]
-id: GO:0045833 ! negative regulation of lipid metabolic process
-is_a: GO:0009892 {is_inferred="true"} ! negative regulation of metabolic process
-is_a: GO:0019216 {is_inferred="true"} ! regulation of lipid metabolic process
-
-[Term]
-id: GO:0045834 ! positive regulation of lipid metabolic process
-is_a: GO:0009893 {is_inferred="true"} ! positive regulation of metabolic process
-is_a: GO:0019216 {is_inferred="true"} ! regulation of lipid metabolic process
-
-[Term]
 id: GO:0045835 ! negative regulation of meiotic nuclear division
 is_a: GO:0010948 {is_inferred="true"} ! negative regulation of cell cycle process
-is_a: GO:0040020 {is_inferred="true"} ! regulation of meiotic nuclear division
-is_a: GO:0051447 {is_inferred="true"} ! negative regulation of meiotic cell cycle
-is_a: GO:0051784 {is_inferred="true"} ! negative regulation of nuclear division
 
 [Term]
 id: GO:0045836 ! positive regulation of meiotic nuclear division
-is_a: GO:0040020 {is_inferred="true"} ! regulation of meiotic nuclear division
-is_a: GO:0051446 {is_inferred="true"} ! positive regulation of meiotic cell cycle
-is_a: GO:0051785 {is_inferred="true"} ! positive regulation of nuclear division
 is_a: GO:0090068 {is_inferred="true"} ! positive regulation of cell cycle process
 
 [Term]
@@ -39499,24 +37482,6 @@
 is_a: GO:0051054 {is_inferred="true"} ! positive regulation of DNA metabolic process
 
 [Term]
-id: GO:0045912 ! negative regulation of carbohydrate metabolic process
-is_a: GO:0006109 {is_inferred="true"} ! regulation of carbohydrate metabolic process
-is_a: GO:0009892 {is_inferred="true"} ! negative regulation of metabolic process
-
-[Term]
-id: GO:0045913 ! positive regulation of carbohydrate metabolic process
-is_a: GO:0006109 {is_inferred="true"} ! regulation of carbohydrate metabolic process
-is_a: GO:0009893 {is_inferred="true"} ! positive regulation of metabolic process
-
-[Term]
-id: GO:0045914 ! negative regulation of catecholamine metabolic process
-is_a: GO:0042069 {is_inferred="true"} ! regulation of catecholamine metabolic process
-
-[Term]
-id: GO:0045915 ! positive regulation of catecholamine metabolic process
-is_a: GO:0042069 {is_inferred="true"} ! regulation of catecholamine metabolic process
-
-[Term]
 id: GO:0045916 ! negative regulation of complement activation
 is_a: GO:0002698 {is_inferred="true"} ! negative regulation of immune effector process
 is_a: GO:0002921 {is_inferred="true"} ! negative regulation of humoral immune response
@@ -39541,16 +37506,6 @@
 is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
 
 [Term]
-id: GO:0045920 ! negative regulation of exocytosis
-is_a: GO:0017157 {is_inferred="true"} ! regulation of exocytosis
-is_a: GO:1903531 {is_inferred="true"} ! negative regulation of secretion by cell
-
-[Term]
-id: GO:0045921 ! positive regulation of exocytosis
-is_a: GO:0017157 {is_inferred="true"} ! regulation of exocytosis
-is_a: GO:1903532 {is_inferred="true"} ! positive regulation of secretion by cell
-
-[Term]
 id: GO:0045922 ! negative regulation of fatty acid metabolic process
 is_a: GO:0019217 {is_inferred="true"} ! regulation of fatty acid metabolic process
 is_a: GO:0031324 {is_inferred="true"} ! negative regulation of cellular metabolic process
@@ -39563,16 +37518,6 @@
 is_a: GO:0045834 {is_inferred="true"} ! positive regulation of lipid metabolic process
 
 [Term]
-id: GO:0045926 ! negative regulation of growth
-is_a: GO:0040008 {is_inferred="true"} ! regulation of growth
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
-
-[Term]
-id: GO:0045927 ! positive regulation of growth
-is_a: GO:0040008 {is_inferred="true"} ! regulation of growth
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
-
-[Term]
 id: GO:0045928 ! negative regulation of juvenile hormone metabolic process
 is_a: GO:0007556 {is_inferred="true"} ! regulation of juvenile hormone metabolic process
 is_a: GO:0032351 {is_inferred="true"} ! negative regulation of hormone metabolic process
@@ -39595,16 +37540,6 @@
 is_a: GO:0045787 {is_inferred="true"} ! positive regulation of cell cycle
 
 [Term]
-id: GO:0045932 ! negative regulation of muscle contraction
-is_a: GO:0006937 {is_inferred="true"} ! regulation of muscle contraction
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-
-[Term]
-id: GO:0045933 ! positive regulation of muscle contraction
-is_a: GO:0006937 {is_inferred="true"} ! regulation of muscle contraction
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-
-[Term]
 id: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process
 is_a: GO:0019219 {is_inferred="true"} ! regulation of nucleobase-containing compound metabolic process
 is_a: GO:0031324 {is_inferred="true"} ! negative regulation of cellular metabolic process
@@ -39627,23 +37562,6 @@
 is_a: GO:0019220 {is_inferred="true"} ! regulation of phosphate metabolic process
 
 [Term]
-id: GO:0045938 ! positive regulation of circadian sleep/wake cycle, sleep
-is_a: GO:0042753 {is_inferred="true"} ! positive regulation of circadian rhythm
-is_a: GO:0045187 {is_inferred="true"} ! regulation of circadian sleep/wake cycle, sleep
-is_a: GO:0048520 {is_inferred="true"} ! positive regulation of behavior
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-
-[Term]
-id: GO:0045939 ! negative regulation of steroid metabolic process
-is_a: GO:0019218 {is_inferred="true"} ! regulation of steroid metabolic process
-is_a: GO:0045833 {is_inferred="true"} ! negative regulation of lipid metabolic process
-
-[Term]
-id: GO:0045940 ! positive regulation of steroid metabolic process
-is_a: GO:0019218 {is_inferred="true"} ! regulation of steroid metabolic process
-is_a: GO:0045834 {is_inferred="true"} ! positive regulation of lipid metabolic process
-
-[Term]
 id: GO:0045942 ! negative regulation of phosphorus utilization
 is_a: GO:0006795 {is_inferred="true"} ! regulation of phosphorus utilization
 is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
@@ -39861,36 +37779,6 @@
 is_a: GO:0045935 {is_inferred="true"} ! positive regulation of nucleobase-containing compound metabolic process
 
 [Term]
-id: GO:0045986 ! negative regulation of smooth muscle contraction
-is_a: GO:0006940 {is_inferred="true"} ! regulation of smooth muscle contraction
-is_a: GO:0045932 {is_inferred="true"} ! negative regulation of muscle contraction
-
-[Term]
-id: GO:0045987 ! positive regulation of smooth muscle contraction
-is_a: GO:0006940 {is_inferred="true"} ! regulation of smooth muscle contraction
-is_a: GO:0045933 {is_inferred="true"} ! positive regulation of muscle contraction
-
-[Term]
-id: GO:0045988 ! negative regulation of striated muscle contraction
-is_a: GO:0006942 {is_inferred="true"} ! regulation of striated muscle contraction
-is_a: GO:0045932 {is_inferred="true"} ! negative regulation of muscle contraction
-
-[Term]
-id: GO:0045989 ! positive regulation of striated muscle contraction
-is_a: GO:0006942 {is_inferred="true"} ! regulation of striated muscle contraction
-is_a: GO:0045933 {is_inferred="true"} ! positive regulation of muscle contraction
-
-[Term]
-id: GO:0045992 ! negative regulation of embryonic development
-is_a: GO:0045995 {is_inferred="true"} ! regulation of embryonic development
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-
-[Term]
-id: GO:0045995 ! regulation of embryonic development
-is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
-
-[Term]
 id: GO:0045997 ! negative regulation of ecdysteroid biosynthetic process
 is_a: GO:0007554 {is_inferred="true"} ! regulation of ecdysteroid biosynthetic process
 is_a: GO:0045965 {is_inferred="true"} ! negative regulation of ecdysteroid metabolic process
@@ -39944,10 +37832,6 @@
 is_a: GO:0046006 {is_inferred="true"} ! regulation of activated T cell proliferation
 
 [Term]
-id: GO:0046010 ! positive regulation of circadian sleep/wake cycle, non-REM sleep
-is_a: GO:0045188 {is_inferred="true"} ! regulation of circadian sleep/wake cycle, non-REM sleep
-
-[Term]
 id: GO:0046013 ! regulation of T cell homeostatic proliferation
 is_a: GO:0032844 {is_inferred="true"} ! regulation of homeostatic process
 is_a: GO:0042129 {is_inferred="true"} ! regulation of T cell proliferation
@@ -40712,12 +38596,6 @@
 is_a: GO:0046176 {is_inferred="true"} ! aldonic acid catabolic process
 
 [Term]
-id: GO:0046184 ! aldehyde biosynthetic process
-is_a: GO:0006081 {is_inferred="true"} ! cellular aldehyde metabolic process
-is_a: GO:0044711 {is_inferred="true"} ! single-organism biosynthetic process
-is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
-
-[Term]
 id: GO:0046185 ! aldehyde catabolic process
 is_a: GO:0006081 {is_inferred="true"} ! cellular aldehyde metabolic process
 is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
@@ -41535,10 +39413,6 @@
 is_a: GO:0019580 {is_inferred="true"} ! galactarate metabolic process
 
 [Term]
-id: GO:0046394 ! carboxylic acid biosynthetic process
-is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
-
-[Term]
 id: GO:0046395 ! carboxylic acid catabolic process
 is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 
@@ -42081,6 +39955,7 @@
 [Term]
 id: GO:0046595 ! establishment of pole plasm mRNA localization
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
 is_a: GO:1902578 {is_inferred="true"} ! single-organism localization
 
 [Term]
@@ -42359,12 +40234,6 @@
 is_a: GO:0046671 {is_inferred="true"} ! negative regulation of retinal cell programmed cell death
 
 [Term]
-id: GO:0046676 ! negative regulation of insulin secretion
-is_a: GO:0050709 {is_inferred="true"} ! negative regulation of protein secretion
-is_a: GO:0050796 {is_inferred="true"} ! regulation of insulin secretion
-is_a: GO:0090278 {is_inferred="true"} ! negative regulation of peptide hormone secretion
-
-[Term]
 id: GO:0046677 ! response to antibiotic
 is_a: GO:0042221 {is_inferred="true"} ! response to chemical
 
@@ -42418,10 +40287,6 @@
 is_a: GO:0010035 {is_inferred="true"} ! response to inorganic substance
 
 [Term]
-id: GO:0046692 ! sperm competition
-is_a: GO:0044703 {is_inferred="true"} ! multi-organism reproductive process
-
-[Term]
 id: GO:0046700 ! heterocycle catabolic process
 is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
 
@@ -42681,18 +40546,6 @@
 is_a: GO:0005501 {is_inferred="true"} ! retinoid binding
 
 [Term]
-id: GO:0046877 ! regulation of saliva secretion
-is_a: GO:0044058 {is_inferred="true"} ! regulation of digestive system process
-is_a: GO:0050878 {is_inferred="true"} ! regulation of body fluid levels
-is_a: GO:0051046 {is_inferred="true"} ! regulation of secretion
-
-[Term]
-id: GO:0046878 ! positive regulation of saliva secretion
-is_a: GO:0046877 {is_inferred="true"} ! regulation of saliva secretion
-is_a: GO:0051047 {is_inferred="true"} ! positive regulation of secretion
-is_a: GO:0060456 {is_inferred="true"} ! positive regulation of digestive system process
-
-[Term]
 id: GO:0046880 ! regulation of follicle-stimulating hormone secretion
 is_a: GO:0032276 {is_inferred="true"} ! regulation of gonadotropin secretion
 
@@ -42707,47 +40560,6 @@
 is_a: GO:0046880 {is_inferred="true"} ! regulation of follicle-stimulating hormone secretion
 
 [Term]
-id: GO:0046883 ! regulation of hormone secretion
-is_a: GO:0010646 {is_inferred="true"} ! regulation of cell communication
-is_a: GO:0010817 {is_inferred="true"} ! regulation of hormone levels
-is_a: GO:0023051 {is_inferred="true"} ! regulation of signaling
-is_a: GO:1903530 {is_inferred="true"} ! regulation of secretion by cell
-
-[Term]
-id: GO:0046885 ! regulation of hormone biosynthetic process
-is_a: GO:0032350 {is_inferred="true"} ! regulation of hormone metabolic process
-
-[Term]
-id: GO:0046886 ! positive regulation of hormone biosynthetic process
-is_a: GO:0032352 {is_inferred="true"} ! positive regulation of hormone metabolic process
-is_a: GO:0046885 {is_inferred="true"} ! regulation of hormone biosynthetic process
-
-[Term]
-id: GO:0046887 ! positive regulation of hormone secretion
-is_a: GO:0010647 {is_inferred="true"} ! positive regulation of cell communication
-is_a: GO:0023056 {is_inferred="true"} ! positive regulation of signaling
-is_a: GO:0046883 {is_inferred="true"} ! regulation of hormone secretion
-is_a: GO:1903532 {is_inferred="true"} ! positive regulation of secretion by cell
-
-[Term]
-id: GO:0046888 ! negative regulation of hormone secretion
-is_a: GO:0010648 {is_inferred="true"} ! negative regulation of cell communication
-is_a: GO:0023057 {is_inferred="true"} ! negative regulation of signaling
-is_a: GO:0046883 {is_inferred="true"} ! regulation of hormone secretion
-is_a: GO:1903531 {is_inferred="true"} ! negative regulation of secretion by cell
-
-[Term]
-id: GO:0046889 ! positive regulation of lipid biosynthetic process
-is_a: GO:0009891 {is_inferred="true"} ! positive regulation of biosynthetic process
-is_a: GO:0045834 {is_inferred="true"} ! positive regulation of lipid metabolic process
-is_a: GO:0046890 {is_inferred="true"} ! regulation of lipid biosynthetic process
-
-[Term]
-id: GO:0046890 ! regulation of lipid biosynthetic process
-is_a: GO:0009889 {is_inferred="true"} ! regulation of biosynthetic process
-is_a: GO:0019216 {is_inferred="true"} ! regulation of lipid metabolic process
-
-[Term]
 id: GO:0046898 ! response to cycloheximide
 is_a: GO:0010243 {is_inferred="true"} ! response to organonitrogen compound
 is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
@@ -42823,11 +40635,6 @@
 is_a: GO:0046937 {is_inferred="true"} ! phytochelatin metabolic process
 
 [Term]
-id: GO:0046942 ! carboxylic acid transport
-is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
-
-[Term]
 id: GO:0046943 ! carboxylic acid transmembrane transporter activity
 is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 
@@ -43246,10 +41053,6 @@
 is_a: GO:0097425 {is_inferred="true"} ! smooth endoplasmic reticulum part
 
 [Term]
-id: GO:0048240 ! sperm capacitation
-is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
-
-[Term]
 id: GO:0048241 ! epinephrine transport
 is_a: GO:0051937 {is_inferred="true"} ! catecholamine transport
 
@@ -43260,11 +41063,6 @@
 is_a: GO:0050432 {is_inferred="true"} ! catecholamine secretion
 
 [Term]
-id: GO:0048243 ! norepinephrine secretion
-is_a: GO:0015874 {is_inferred="true"} ! norepinephrine transport
-is_a: GO:0050432 {is_inferred="true"} ! catecholamine secretion
-
-[Term]
 id: GO:0048245 ! eosinophil chemotaxis
 is_a: GO:0071621 {is_inferred="true"} ! granulocyte chemotaxis
 
@@ -43630,10 +41428,6 @@
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 
 [Term]
-id: GO:0048469 ! cell maturation
-is_a: GO:0021700 {is_inferred="true"} ! developmental maturation
-
-[Term]
 id: GO:0048473 ! D-methionine transport
 is_a: GO:0015821 {is_inferred="true"} ! methionine transport
 is_a: GO:0042940 {is_inferred="true"} ! D-amino acid transport
@@ -43644,10 +41438,6 @@
 is_a: GO:0043865 {is_inferred="true"} ! methionine transmembrane transporter activity
 
 [Term]
-id: GO:0048477 ! oogenesis
-is_a: GO:0007281 {is_inferred="true"} ! germ cell development
-
-[Term]
 id: GO:0048481 ! plant ovule development
 is_a: GO:0099402 {is_inferred="true"} ! plant organ development
 
@@ -43699,39 +41489,6 @@
 is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
 
 [Term]
-id: GO:0048515 ! spermatid differentiation
-is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
-is_a: GO:0030154 {is_inferred="true"} ! cell differentiation
-
-[Term]
-id: GO:0048518 ! positive regulation of biological process
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-
-[Term]
-id: GO:0048519 ! negative regulation of biological process
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-
-[Term]
-id: GO:0048520 ! positive regulation of behavior
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
-is_a: GO:0050795 {is_inferred="true"} ! regulation of behavior
-
-[Term]
-id: GO:0048521 ! negative regulation of behavior
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
-is_a: GO:0050795 {is_inferred="true"} ! regulation of behavior
-
-[Term]
-id: GO:0048522 ! positive regulation of cellular process
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
-is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
-
-[Term]
-id: GO:0048523 ! negative regulation of cellular process
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
-is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
-
-[Term]
 id: GO:0048524 ! positive regulation of viral process
 is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
@@ -43820,36 +41577,6 @@
 is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
 
 [Term]
-id: GO:0048580 ! regulation of post-embryonic development
-is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
-
-[Term]
-id: GO:0048581 ! negative regulation of post-embryonic development
-is_a: GO:0048580 {is_inferred="true"} ! regulation of post-embryonic development
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-
-[Term]
-id: GO:0048582 ! positive regulation of post-embryonic development
-is_a: GO:0048580 {is_inferred="true"} ! regulation of post-embryonic development
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-
-[Term]
-id: GO:0048583 ! regulation of response to stimulus
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-
-[Term]
-id: GO:0048584 ! positive regulation of response to stimulus
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
-is_a: GO:0048583 {is_inferred="true"} ! regulation of response to stimulus
-
-[Term]
-id: GO:0048585 ! negative regulation of response to stimulus
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
-is_a: GO:0048583 {is_inferred="true"} ! regulation of response to stimulus
-
-[Term]
 id: GO:0048586 ! regulation of long-day photoperiodism, flowering
 is_a: GO:2000028 {is_inferred="true"} ! regulation of photoperiodism, flowering
 
@@ -43908,23 +41635,6 @@
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 
 [Term]
-id: GO:0048638 ! regulation of developmental growth
-is_a: GO:0040008 {is_inferred="true"} ! regulation of growth
-is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
-
-[Term]
-id: GO:0048639 ! positive regulation of developmental growth
-is_a: GO:0045927 {is_inferred="true"} ! positive regulation of growth
-is_a: GO:0048638 {is_inferred="true"} ! regulation of developmental growth
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
-
-[Term]
-id: GO:0048640 ! negative regulation of developmental growth
-is_a: GO:0045926 {is_inferred="true"} ! negative regulation of growth
-is_a: GO:0048638 {is_inferred="true"} ! regulation of developmental growth
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
-
-[Term]
 id: GO:0048641 ! regulation of skeletal muscle tissue development
 is_a: GO:0016202 {is_inferred="true"} ! regulation of striated muscle tissue development
 
@@ -44157,10 +41867,6 @@
 is_a: GO:0016050 {is_inferred="true"} ! vesicle organization
 
 [Term]
-id: GO:0048754 ! branching morphogenesis of an epithelial tube
-is_a: GO:0035239 {is_inferred="true"} ! tube morphogenesis
-
-[Term]
 id: GO:0048759 ! xylem vessel member cell differentiation
 is_a: GO:1905177 {is_inferred="true"} ! tracheary element differentiation
 
@@ -44336,10 +42042,6 @@
 is_a: GO:0048856 {is_inferred="true"} ! anatomical structure development
 
 [Term]
-id: GO:0048878 ! chemical homeostasis
-is_a: GO:0042592 {is_inferred="true"} ! homeostatic process
-
-[Term]
 id: GO:0048882 ! lateral line development
 is_a: GO:0009888 {is_inferred="true"} ! tissue development
 
@@ -44384,14 +42086,6 @@
 is_a: GO:0050427 {is_inferred="true"} ! 3'-phosphoadenosine 5'-phosphosulfate metabolic process
 
 [Term]
-id: GO:0050432 ! catecholamine secretion
-is_a: GO:0051937 {is_inferred="true"} ! catecholamine transport
-
-[Term]
-id: GO:0050433 ! regulation of catecholamine secretion
-is_a: GO:1903530 {is_inferred="true"} ! regulation of secretion by cell
-
-[Term]
 id: GO:0050434 ! positive regulation of viral transcription
 is_a: GO:0010628 {is_inferred="true"} ! positive regulation of gene expression
 is_a: GO:0046782 {is_inferred="true"} ! regulation of viral transcription
@@ -44509,23 +42203,6 @@
 is_a: GO:0050666 {is_inferred="true"} ! regulation of homocysteine metabolic process
 
 [Term]
-id: GO:0050670 ! regulation of lymphocyte proliferation
-is_a: GO:0032944 {is_inferred="true"} ! regulation of mononuclear cell proliferation
-is_a: GO:0051249 {is_inferred="true"} ! regulation of lymphocyte activation
-
-[Term]
-id: GO:0050671 ! positive regulation of lymphocyte proliferation
-is_a: GO:0032946 {is_inferred="true"} ! positive regulation of mononuclear cell proliferation
-is_a: GO:0050670 {is_inferred="true"} ! regulation of lymphocyte proliferation
-is_a: GO:0051251 {is_inferred="true"} ! positive regulation of lymphocyte activation
-
-[Term]
-id: GO:0050672 ! negative regulation of lymphocyte proliferation
-is_a: GO:0032945 {is_inferred="true"} ! negative regulation of mononuclear cell proliferation
-is_a: GO:0050670 {is_inferred="true"} ! regulation of lymphocyte proliferation
-is_a: GO:0051250 {is_inferred="true"} ! negative regulation of lymphocyte activation
-
-[Term]
 id: GO:0050675 ! regulation of urothelial cell proliferation
 is_a: GO:0050678 {is_inferred="true"} ! regulation of epithelial cell proliferation
 
@@ -44540,20 +42217,6 @@
 is_a: GO:0050679 {is_inferred="true"} ! positive regulation of epithelial cell proliferation
 
 [Term]
-id: GO:0050678 ! regulation of epithelial cell proliferation
-is_a: GO:0042127 {is_inferred="true"} ! regulation of cell proliferation
-
-[Term]
-id: GO:0050679 ! positive regulation of epithelial cell proliferation
-is_a: GO:0008284 {is_inferred="true"} ! positive regulation of cell proliferation
-is_a: GO:0050678 {is_inferred="true"} ! regulation of epithelial cell proliferation
-
-[Term]
-id: GO:0050680 ! negative regulation of epithelial cell proliferation
-is_a: GO:0008285 {is_inferred="true"} ! negative regulation of cell proliferation
-is_a: GO:0050678 {is_inferred="true"} ! regulation of epithelial cell proliferation
-
-[Term]
 id: GO:0050684 ! regulation of mRNA processing
 is_a: GO:0010468 {is_inferred="true"} ! regulation of gene expression
 is_a: GO:1903311 {is_inferred="true"} ! regulation of mRNA metabolic process
@@ -44613,17 +42276,6 @@
 is_a: GO:0050708 {is_inferred="true"} ! regulation of protein secretion
 
 [Term]
-id: GO:0050708 ! regulation of protein secretion
-is_a: GO:0051223 {is_inferred="true"} ! regulation of protein transport
-is_a: GO:1903530 {is_inferred="true"} ! regulation of secretion by cell
-
-[Term]
-id: GO:0050709 ! negative regulation of protein secretion
-is_a: GO:0050708 {is_inferred="true"} ! regulation of protein secretion
-is_a: GO:0051224 {is_inferred="true"} ! negative regulation of protein transport
-is_a: GO:1903531 {is_inferred="true"} ! negative regulation of secretion by cell
-
-[Term]
 id: GO:0050710 ! negative regulation of cytokine secretion
 is_a: GO:0001818 {is_inferred="true"} ! negative regulation of cytokine production
 is_a: GO:0050707 {is_inferred="true"} ! regulation of cytokine secretion
@@ -44645,12 +42297,6 @@
 is_a: GO:0050711 {is_inferred="true"} ! negative regulation of interleukin-1 secretion
 
 [Term]
-id: GO:0050714 ! positive regulation of protein secretion
-is_a: GO:0050708 {is_inferred="true"} ! regulation of protein secretion
-is_a: GO:0051222 {is_inferred="true"} ! positive regulation of protein transport
-is_a: GO:1903532 {is_inferred="true"} ! positive regulation of secretion by cell
-
-[Term]
 id: GO:0050715 ! positive regulation of cytokine secretion
 is_a: GO:0001819 {is_inferred="true"} ! positive regulation of cytokine production
 is_a: GO:0050707 {is_inferred="true"} ! regulation of cytokine secretion
@@ -44706,20 +42352,6 @@
 is_a: GO:0050721 {is_inferred="true"} ! regulation of interleukin-1 alpha biosynthetic process
 
 [Term]
-id: GO:0050727 ! regulation of inflammatory response
-is_a: GO:0031347 {is_inferred="true"} ! regulation of defense response
-
-[Term]
-id: GO:0050728 ! negative regulation of inflammatory response
-is_a: GO:0031348 {is_inferred="true"} ! negative regulation of defense response
-is_a: GO:0050727 {is_inferred="true"} ! regulation of inflammatory response
-
-[Term]
-id: GO:0050729 ! positive regulation of inflammatory response
-is_a: GO:0031349 {is_inferred="true"} ! positive regulation of defense response
-is_a: GO:0050727 {is_inferred="true"} ! regulation of inflammatory response
-
-[Term]
 id: GO:0050730 ! regulation of peptidyl-tyrosine phosphorylation
 is_a: GO:0001932 {is_inferred="true"} ! regulation of protein phosphorylation
 
@@ -44818,20 +42450,6 @@
 is_a: GO:0050764 {is_inferred="true"} ! regulation of phagocytosis
 
 [Term]
-id: GO:0050767 ! regulation of neurogenesis
-is_a: GO:0051960 {is_inferred="true"} ! regulation of nervous system development
-
-[Term]
-id: GO:0050768 ! negative regulation of neurogenesis
-is_a: GO:0050767 {is_inferred="true"} ! regulation of neurogenesis
-is_a: GO:0051961 {is_inferred="true"} ! negative regulation of nervous system development
-
-[Term]
-id: GO:0050769 ! positive regulation of neurogenesis
-is_a: GO:0050767 {is_inferred="true"} ! regulation of neurogenesis
-is_a: GO:0051962 {is_inferred="true"} ! positive regulation of nervous system development
-
-[Term]
 id: GO:0050770 ! regulation of axonogenesis
 is_a: GO:0010769 {is_inferred="true"} ! regulation of cell morphogenesis involved in differentiation
 is_a: GO:0010975 {is_inferred="true"} ! regulation of neuron projection development
@@ -44865,23 +42483,6 @@
 is_a: GO:1900006 {is_inferred="true"} ! positive regulation of dendrite development
 
 [Term]
-id: GO:0050776 ! regulation of immune response
-is_a: GO:0002682 {is_inferred="true"} ! regulation of immune system process
-is_a: GO:0048583 {is_inferred="true"} ! regulation of response to stimulus
-
-[Term]
-id: GO:0050777 ! negative regulation of immune response
-is_a: GO:0002683 {is_inferred="true"} ! negative regulation of immune system process
-is_a: GO:0048585 {is_inferred="true"} ! negative regulation of response to stimulus
-is_a: GO:0050776 {is_inferred="true"} ! regulation of immune response
-
-[Term]
-id: GO:0050778 ! positive regulation of immune response
-is_a: GO:0002684 {is_inferred="true"} ! positive regulation of immune system process
-is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
-is_a: GO:0050776 {is_inferred="true"} ! regulation of immune response
-
-[Term]
 id: GO:0050783 ! cocaine metabolic process
 is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
 is_a: GO:0046448 {is_inferred="true"} ! tropane alkaloid metabolic process
@@ -44909,23 +42510,6 @@
 is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
 
 [Term]
-id: GO:0050793 ! regulation of developmental process
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-
-[Term]
-id: GO:0050794 ! regulation of cellular process
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-
-[Term]
-id: GO:0050795 ! regulation of behavior
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-
-[Term]
-id: GO:0050796 ! regulation of insulin secretion
-is_a: GO:0050708 {is_inferred="true"} ! regulation of protein secretion
-is_a: GO:0090276 {is_inferred="true"} ! regulation of peptide hormone secretion
-
-[Term]
 id: GO:0050799 ! cocaine biosynthetic process
 is_a: GO:0009710 {is_inferred="true"} ! tropane alkaloid biosynthetic process
 is_a: GO:0019438 {is_inferred="true"} ! aromatic compound biosynthetic process
@@ -44932,15 +42516,6 @@
 is_a: GO:0050783 {is_inferred="true"} ! cocaine metabolic process
 
 [Term]
-id: GO:0050801 ! ion homeostasis
-is_a: GO:0048878 {is_inferred="true"} ! chemical homeostasis
-
-[Term]
-id: GO:0050802 ! circadian sleep/wake cycle, sleep
-is_a: GO:0030431 {is_inferred="true"} ! sleep
-is_a: GO:0044708 {is_inferred="true"} ! single-organism behavior
-
-[Term]
 id: GO:0050804 ! modulation of synaptic transmission
 is_a: GO:0010646 {is_inferred="true"} ! regulation of cell communication
 is_a: GO:0023051 {is_inferred="true"} ! regulation of signaling
@@ -44971,11 +42546,6 @@
 is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
 
 [Term]
-id: GO:0050810 ! regulation of steroid biosynthetic process
-is_a: GO:0019218 {is_inferred="true"} ! regulation of steroid metabolic process
-is_a: GO:0046890 {is_inferred="true"} ! regulation of lipid biosynthetic process
-
-[Term]
 id: GO:0050812 ! regulation of acyl-CoA biosynthetic process
 is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
 is_a: GO:0042762 {is_inferred="true"} ! regulation of sulfur metabolic process
@@ -45000,20 +42570,6 @@
 is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
 
 [Term]
-id: GO:0050818 ! regulation of coagulation
-is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
-
-[Term]
-id: GO:0050819 ! negative regulation of coagulation
-is_a: GO:0050818 {is_inferred="true"} ! regulation of coagulation
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-
-[Term]
-id: GO:0050820 ! positive regulation of coagulation
-is_a: GO:0050818 {is_inferred="true"} ! regulation of coagulation
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-
-[Term]
 id: GO:0050824 ! water binding
 is_a: GO:0005488 {is_inferred="true"} ! binding
 
@@ -45096,55 +42652,6 @@
 is_a: GO:0050857 {is_inferred="true"} ! positive regulation of antigen receptor-mediated signaling pathway
 
 [Term]
-id: GO:0050863 ! regulation of T cell activation
-is_a: GO:0051249 {is_inferred="true"} ! regulation of lymphocyte activation
-is_a: GO:1903037 {is_inferred="true"} ! regulation of leukocyte cell-cell adhesion
-
-[Term]
-id: GO:0050864 ! regulation of B cell activation
-is_a: GO:0051249 {is_inferred="true"} ! regulation of lymphocyte activation
-
-[Term]
-id: GO:0050865 ! regulation of cell activation
-is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
-
-[Term]
-id: GO:0050866 ! negative regulation of cell activation
-is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
-is_a: GO:0050865 {is_inferred="true"} ! regulation of cell activation
-
-[Term]
-id: GO:0050867 ! positive regulation of cell activation
-is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
-is_a: GO:0050865 {is_inferred="true"} ! regulation of cell activation
-
-[Term]
-id: GO:0050868 ! negative regulation of T cell activation
-is_a: GO:0050863 {is_inferred="true"} ! regulation of T cell activation
-is_a: GO:0051250 {is_inferred="true"} ! negative regulation of lymphocyte activation
-is_a: GO:1903038 {is_inferred="true"} ! negative regulation of leukocyte cell-cell adhesion
-
-[Term]
-id: GO:0050869 ! negative regulation of B cell activation
-is_a: GO:0050864 {is_inferred="true"} ! regulation of B cell activation
-is_a: GO:0051250 {is_inferred="true"} ! negative regulation of lymphocyte activation
-
-[Term]
-id: GO:0050870 ! positive regulation of T cell activation
-is_a: GO:0050863 {is_inferred="true"} ! regulation of T cell activation
-is_a: GO:0051251 {is_inferred="true"} ! positive regulation of lymphocyte activation
-is_a: GO:1903039 {is_inferred="true"} ! positive regulation of leukocyte cell-cell adhesion
-
-[Term]
-id: GO:0050871 ! positive regulation of B cell activation
-is_a: GO:0050864 {is_inferred="true"} ! regulation of B cell activation
-is_a: GO:0051251 {is_inferred="true"} ! positive regulation of lymphocyte activation
-
-[Term]
-id: GO:0050891 ! multicellular organismal water homeostasis
-is_a: GO:0048871 {is_inferred="true"} ! multicellular organismal homeostasis
-
-[Term]
 id: GO:0050897 ! cobalt ion binding
 is_a: GO:0046914 {is_inferred="true"} ! transition metal ion binding
 
@@ -45158,31 +42665,6 @@
 is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
 
 [Term]
-id: GO:0050906 ! detection of stimulus involved in sensory perception
-is_a: GO:0051606 {is_inferred="true"} ! detection of stimulus
-
-[Term]
-id: GO:0050907 ! detection of chemical stimulus involved in sensory perception
-is_a: GO:0009593 {is_inferred="true"} ! detection of chemical stimulus
-is_a: GO:0050906 {is_inferred="true"} ! detection of stimulus involved in sensory perception
-
-[Term]
-id: GO:0050908 ! detection of light stimulus involved in visual perception
-is_a: GO:0050962 {is_inferred="true"} ! detection of light stimulus involved in sensory perception
-
-[Term]
-id: GO:0050910 ! detection of mechanical stimulus involved in sensory perception of sound
-is_a: GO:0050974 {is_inferred="true"} ! detection of mechanical stimulus involved in sensory perception
-
-[Term]
-id: GO:0050911 ! detection of chemical stimulus involved in sensory perception of smell
-is_a: GO:0050907 {is_inferred="true"} ! detection of chemical stimulus involved in sensory perception
-
-[Term]
-id: GO:0050912 ! detection of chemical stimulus involved in sensory perception of taste
-is_a: GO:0050907 {is_inferred="true"} ! detection of chemical stimulus involved in sensory perception
-
-[Term]
 id: GO:0050920 ! regulation of chemotaxis
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
 is_a: GO:0040012 {is_inferred="true"} ! regulation of locomotion
@@ -45303,41 +42785,6 @@
 is_a: GO:0050961 {is_inferred="true"} ! detection of temperature stimulus involved in sensory perception
 
 [Term]
-id: GO:0050961 ! detection of temperature stimulus involved in sensory perception
-is_a: GO:0016048 {is_inferred="true"} ! detection of temperature stimulus
-is_a: GO:0050906 {is_inferred="true"} ! detection of stimulus involved in sensory perception
-
-[Term]
-id: GO:0050962 ! detection of light stimulus involved in sensory perception
-is_a: GO:0009583 {is_inferred="true"} ! detection of light stimulus
-is_a: GO:0050906 {is_inferred="true"} ! detection of stimulus involved in sensory perception
-
-[Term]
-id: GO:0050963 ! detection of electrical stimulus involved in sensory perception
-is_a: GO:0050906 {is_inferred="true"} ! detection of stimulus involved in sensory perception
-is_a: GO:0050981 {is_inferred="true"} ! detection of electrical stimulus
-
-[Term]
-id: GO:0050964 ! detection of electrical stimulus involved in electroception
-is_a: GO:0050963 {is_inferred="true"} ! detection of electrical stimulus involved in sensory perception
-
-[Term]
-id: GO:0050965 ! detection of temperature stimulus involved in sensory perception of pain
-is_a: GO:0050961 {is_inferred="true"} ! detection of temperature stimulus involved in sensory perception
-
-[Term]
-id: GO:0050966 ! detection of mechanical stimulus involved in sensory perception of pain
-is_a: GO:0050974 {is_inferred="true"} ! detection of mechanical stimulus involved in sensory perception
-
-[Term]
-id: GO:0050967 ! detection of electrical stimulus involved in sensory perception of pain
-is_a: GO:0050963 {is_inferred="true"} ! detection of electrical stimulus involved in sensory perception
-
-[Term]
-id: GO:0050968 ! detection of chemical stimulus involved in sensory perception of pain
-is_a: GO:0050907 {is_inferred="true"} ! detection of chemical stimulus involved in sensory perception
-
-[Term]
 id: GO:0050969 ! detection of chemical stimulus involved in magnetoreception
 is_a: GO:0050907 {is_inferred="true"} ! detection of chemical stimulus involved in sensory perception
 
@@ -45350,19 +42797,6 @@
 is_a: GO:0050974 {is_inferred="true"} ! detection of mechanical stimulus involved in sensory perception
 
 [Term]
-id: GO:0050973 ! detection of mechanical stimulus involved in equilibrioception
-is_a: GO:0050974 {is_inferred="true"} ! detection of mechanical stimulus involved in sensory perception
-
-[Term]
-id: GO:0050974 ! detection of mechanical stimulus involved in sensory perception
-is_a: GO:0050906 {is_inferred="true"} ! detection of stimulus involved in sensory perception
-is_a: GO:0050982 {is_inferred="true"} ! detection of mechanical stimulus
-
-[Term]
-id: GO:0050976 ! detection of mechanical stimulus involved in sensory perception of touch
-is_a: GO:0050974 {is_inferred="true"} ! detection of mechanical stimulus involved in sensory perception
-
-[Term]
 id: GO:0050980 ! detection of light stimulus involved in magnetoreception
 is_a: GO:0050962 {is_inferred="true"} ! detection of light stimulus involved in sensory perception
 
@@ -45519,34 +42953,6 @@
 is_a: GO:0051043 {is_inferred="true"} ! regulation of membrane protein ectodomain proteolysis
 
 [Term]
-id: GO:0051046 ! regulation of secretion
-is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
-
-[Term]
-id: GO:0051047 ! positive regulation of secretion
-is_a: GO:0051046 {is_inferred="true"} ! regulation of secretion
-is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
-
-[Term]
-id: GO:0051048 ! negative regulation of secretion
-is_a: GO:0051046 {is_inferred="true"} ! regulation of secretion
-is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
-
-[Term]
-id: GO:0051049 ! regulation of transport
-is_a: GO:0032879 {is_inferred="true"} ! regulation of localization
-
-[Term]
-id: GO:0051050 ! positive regulation of transport
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
-is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
-
-[Term]
-id: GO:0051051 ! negative regulation of transport
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
-is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
-
-[Term]
 id: GO:0051052 ! regulation of DNA metabolic process
 is_a: GO:0019219 {is_inferred="true"} ! regulation of nucleobase-containing compound metabolic process
 is_a: GO:0060255 {is_inferred="true"} ! regulation of macromolecule metabolic process
@@ -45564,12 +42970,6 @@
 is_a: GO:0051052 {is_inferred="true"} ! regulation of DNA metabolic process
 
 [Term]
-id: GO:0051055 ! negative regulation of lipid biosynthetic process
-is_a: GO:0009890 {is_inferred="true"} ! negative regulation of biosynthetic process
-is_a: GO:0045833 {is_inferred="true"} ! negative regulation of lipid metabolic process
-is_a: GO:0046890 {is_inferred="true"} ! regulation of lipid biosynthetic process
-
-[Term]
 id: GO:0051056 ! regulation of small GTPase mediated signal transduction
 is_a: GO:1902531 {is_inferred="true"} ! regulation of intracellular signal transduction
 
@@ -45643,16 +43043,6 @@
 is_a: GO:0051090 {is_inferred="true"} ! regulation of sequence-specific DNA binding transcription factor activity
 
 [Term]
-id: GO:0051093 ! negative regulation of developmental process
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
-is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
-
-[Term]
-id: GO:0051094 ! positive regulation of developmental process
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
-is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
-
-[Term]
 id: GO:0051095 ! regulation of helicase activity
 is_a: GO:0051336 {is_inferred="true"} ! regulation of hydrolase activity
 
@@ -45734,20 +43124,6 @@
 is_a: GO:0051125 {is_inferred="true"} ! regulation of actin nucleation
 
 [Term]
-id: GO:0051128 ! regulation of cellular component organization
-is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
-
-[Term]
-id: GO:0051129 ! negative regulation of cellular component organization
-is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
-is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
-
-[Term]
-id: GO:0051130 ! positive regulation of cellular component organization
-is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
-is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
-
-[Term]
 id: GO:0051133 ! regulation of NK T cell activation
 is_a: GO:0046634 {is_inferred="true"} ! regulation of alpha-beta T cell activation
 
@@ -45905,20 +43281,6 @@
 is_a: GO:1901135 {is_inferred="true"} ! carbohydrate derivative metabolic process
 
 [Term]
-id: GO:0051171 ! regulation of nitrogen compound metabolic process
-is_a: GO:0019222 {is_inferred="true"} ! regulation of metabolic process
-
-[Term]
-id: GO:0051172 ! negative regulation of nitrogen compound metabolic process
-is_a: GO:0009892 {is_inferred="true"} ! negative regulation of metabolic process
-is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
-
-[Term]
-id: GO:0051173 ! positive regulation of nitrogen compound metabolic process
-is_a: GO:0009893 {is_inferred="true"} ! positive regulation of metabolic process
-is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
-
-[Term]
 id: GO:0051174 ! regulation of phosphorus metabolic process
 is_a: GO:0031323 {is_inferred="true"} ! regulation of cellular metabolic process
 
@@ -46020,23 +43382,6 @@
 is_a: GO:0032507 {is_inferred="true"} ! maintenance of protein location in cell
 
 [Term]
-id: GO:0051222 ! positive regulation of protein transport
-is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
-is_a: GO:0051223 {is_inferred="true"} ! regulation of protein transport
-is_a: GO:1904951 {is_inferred="true"} ! positive regulation of establishment of protein localization
-
-[Term]
-id: GO:0051223 ! regulation of protein transport
-is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
-is_a: GO:0070201 {is_inferred="true"} ! regulation of establishment of protein localization
-
-[Term]
-id: GO:0051224 ! negative regulation of protein transport
-is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
-is_a: GO:0051223 {is_inferred="true"} ! regulation of protein transport
-is_a: GO:1904950 {is_inferred="true"} ! negative regulation of establishment of protein localization
-
-[Term]
 id: GO:0051228 ! mitotic spindle disassembly
 is_a: GO:0007052 {is_inferred="true"} ! mitotic spindle organization
 is_a: GO:0051230 {is_inferred="true"} ! spindle disassembly
@@ -46057,20 +43402,6 @@
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
-id: GO:0051239 ! regulation of multicellular organismal process
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-
-[Term]
-id: GO:0051240 ! positive regulation of multicellular organismal process
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
-is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
-
-[Term]
-id: GO:0051241 ! negative regulation of multicellular organismal process
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
-is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
-
-[Term]
 id: GO:0051245 ! negative regulation of cellular defense response
 is_a: GO:0010185 {is_inferred="true"} ! regulation of cellular defense response
 is_a: GO:0031348 {is_inferred="true"} ! negative regulation of defense response
@@ -46091,20 +43422,6 @@
 is_a: GO:0051246 {is_inferred="true"} ! regulation of protein metabolic process
 
 [Term]
-id: GO:0051249 ! regulation of lymphocyte activation
-is_a: GO:0002694 {is_inferred="true"} ! regulation of leukocyte activation
-
-[Term]
-id: GO:0051250 ! negative regulation of lymphocyte activation
-is_a: GO:0002695 {is_inferred="true"} ! negative regulation of leukocyte activation
-is_a: GO:0051249 {is_inferred="true"} ! regulation of lymphocyte activation
-
-[Term]
-id: GO:0051251 ! positive regulation of lymphocyte activation
-is_a: GO:0002696 {is_inferred="true"} ! positive regulation of leukocyte activation
-is_a: GO:0051249 {is_inferred="true"} ! regulation of lymphocyte activation
-
-[Term]
 id: GO:0051252 ! regulation of RNA metabolic process
 is_a: GO:0019219 {is_inferred="true"} ! regulation of nucleobase-containing compound metabolic process
 is_a: GO:0060255 {is_inferred="true"} ! regulation of macromolecule metabolic process
@@ -46137,20 +43454,6 @@
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
-id: GO:0051270 ! regulation of cellular component movement
-is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
-
-[Term]
-id: GO:0051271 ! negative regulation of cellular component movement
-is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
-is_a: GO:0051270 {is_inferred="true"} ! regulation of cellular component movement
-
-[Term]
-id: GO:0051272 ! positive regulation of cellular component movement
-is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
-is_a: GO:0051270 {is_inferred="true"} ! regulation of cellular component movement
-
-[Term]
 id: GO:0051274 ! beta-glucan biosynthetic process
 is_a: GO:0009250 {is_inferred="true"} ! glucan biosynthetic process
 is_a: GO:0051273 {is_inferred="true"} ! beta-glucan metabolic process
@@ -46241,10 +43544,6 @@
 is_a: GO:0031023 {is_inferred="true"} ! microtubule organizing center organization
 
 [Term]
-id: GO:0051302 ! regulation of cell division
-is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
-
-[Term]
 id: GO:0051303 ! establishment of chromosome localization
 is_a: GO:0050000 {is_inferred="true"} ! chromosome localization
 
@@ -46286,10 +43585,6 @@
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
-id: GO:0051321 ! meiotic cell cycle
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-
-[Term]
 id: GO:0051327 ! meiotic M phase
 is_a: GO:0098762 {is_inferred="true"} ! meiotic cell cycle phase
 
@@ -46404,14 +43699,6 @@
 is_a: GO:0051341 {is_inferred="true"} ! regulation of oxidoreductase activity
 
 [Term]
-id: GO:0051355 ! proprioception involved in equilibrioception
-is_a: GO:0019230 {is_inferred="true"} ! proprioception
-
-[Term]
-id: GO:0051356 ! visual perception involved in equilibrioception
-is_a: GO:0007601 {is_inferred="true"} ! visual perception
-
-[Term]
 id: GO:0051378 ! serotonin binding
 is_a: GO:0070405 {is_inferred="true"} ! ammonium ion binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
@@ -46567,23 +43854,6 @@
 is_a: GO:0051438 {is_inferred="true"} ! regulation of ubiquitin-protein transferase activity
 
 [Term]
-id: GO:0051445 ! regulation of meiotic cell cycle
-is_a: GO:0051726 {is_inferred="true"} ! regulation of cell cycle
-is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
-
-[Term]
-id: GO:0051446 ! positive regulation of meiotic cell cycle
-is_a: GO:0045787 {is_inferred="true"} ! positive regulation of cell cycle
-is_a: GO:0051445 {is_inferred="true"} ! regulation of meiotic cell cycle
-is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
-
-[Term]
-id: GO:0051447 ! negative regulation of meiotic cell cycle
-is_a: GO:0045786 {is_inferred="true"} ! negative regulation of cell cycle
-is_a: GO:0051445 {is_inferred="true"} ! regulation of meiotic cell cycle
-is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
-
-[Term]
 id: GO:0051452 ! intracellular pH reduction
 is_a: GO:0045851 {is_inferred="true"} ! pH reduction
 
@@ -47245,10 +44515,6 @@
 is_a: GO:0051644 {is_inferred="true"} ! plastid localization
 
 [Term]
-id: GO:0051674 ! localization of cell
-is_a: GO:0051179 {is_inferred="true"} ! localization
-
-[Term]
 id: GO:0051677 ! pullulan biosynthetic process
 is_a: GO:0009250 {is_inferred="true"} ! glucan biosynthetic process
 is_a: GO:0051676 {is_inferred="true"} ! pullulan metabolic process
@@ -47350,10 +44616,6 @@
 is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
 
 [Term]
-id: GO:0051726 ! regulation of cell cycle
-is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
-
-[Term]
 id: GO:0051738 ! xanthophyll binding
 is_a: GO:0019840 {is_inferred="true"} ! isoprenoid binding
 
@@ -47398,30 +44660,6 @@
 is_a: GO:0051769 {is_inferred="true"} ! regulation of nitric-oxide synthase biosynthetic process
 
 [Term]
-id: GO:0051781 ! positive regulation of cell division
-is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
-is_a: GO:0051302 {is_inferred="true"} ! regulation of cell division
-
-[Term]
-id: GO:0051782 ! negative regulation of cell division
-is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
-is_a: GO:0051302 {is_inferred="true"} ! regulation of cell division
-
-[Term]
-id: GO:0051783 ! regulation of nuclear division
-is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
-
-[Term]
-id: GO:0051784 ! negative regulation of nuclear division
-is_a: GO:0010639 {is_inferred="true"} ! negative regulation of organelle organization
-is_a: GO:0051783 {is_inferred="true"} ! regulation of nuclear division
-
-[Term]
-id: GO:0051785 ! positive regulation of nuclear division
-is_a: GO:0010638 {is_inferred="true"} ! positive regulation of organelle organization
-is_a: GO:0051783 {is_inferred="true"} ! regulation of nuclear division
-
-[Term]
 id: GO:0051790 ! short-chain fatty acid biosynthetic process
 is_a: GO:0006633 {is_inferred="true"} ! fatty acid biosynthetic process
 is_a: GO:0046459 {is_inferred="true"} ! short-chain fatty acid metabolic process
@@ -47657,14 +44895,6 @@
 is_a: GO:0051924 {is_inferred="true"} ! regulation of calcium ion transport
 
 [Term]
-id: GO:0051930 ! regulation of sensory perception of pain
-is_a: GO:0051931 {is_inferred="true"} ! regulation of sensory perception
-
-[Term]
-id: GO:0051931 ! regulation of sensory perception
-is_a: GO:0031644 {is_inferred="true"} ! regulation of neurological system process
-
-[Term]
 id: GO:0051933 ! amino acid neurotransmitter reuptake
 is_a: GO:0098810 {is_inferred="true"} ! neurotransmitter reuptake
 is_a: GO:1902837 {is_inferred="true"} ! amino acid import into cell
@@ -47685,11 +44915,6 @@
 is_a: GO:0051939 {is_inferred="true"} ! gamma-aminobutyric acid import
 
 [Term]
-id: GO:0051937 ! catecholamine transport
-is_a: GO:0015844 {is_inferred="true"} ! monoamine transport
-is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
-
-[Term]
 id: GO:0051938 ! L-glutamate import
 is_a: GO:0015813 {is_inferred="true"} ! L-glutamate transport
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
@@ -47764,20 +44989,6 @@
 is_a: GO:1900922 {is_inferred="true"} ! positive regulation of L-glutamate import
 
 [Term]
-id: GO:0051952 ! regulation of amine transport
-is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
-
-[Term]
-id: GO:0051953 ! negative regulation of amine transport
-is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
-is_a: GO:0051952 {is_inferred="true"} ! regulation of amine transport
-
-[Term]
-id: GO:0051954 ! positive regulation of amine transport
-is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
-is_a: GO:0051952 {is_inferred="true"} ! regulation of amine transport
-
-[Term]
 id: GO:0051955 ! regulation of amino acid transport
 is_a: GO:0032890 {is_inferred="true"} ! regulation of organic acid transport
 is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
@@ -47800,22 +45011,6 @@
 is_a: GO:0042886 {is_inferred="true"} ! amide transport
 
 [Term]
-id: GO:0051960 ! regulation of nervous system development
-is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
-
-[Term]
-id: GO:0051961 ! negative regulation of nervous system development
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-is_a: GO:0051960 {is_inferred="true"} ! regulation of nervous system development
-
-[Term]
-id: GO:0051962 ! positive regulation of nervous system development
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-is_a: GO:0051960 {is_inferred="true"} ! regulation of nervous system development
-
-[Term]
 id: GO:0051963 ! regulation of synapse assembly
 is_a: GO:0044087 {is_inferred="true"} ! regulation of cellular component biogenesis
 is_a: GO:0050807 {is_inferred="true"} ! regulation of synapse organization
@@ -48179,13 +45374,6 @@
 is_a: GO:0052783 {is_inferred="true"} ! reuteran metabolic process
 
 [Term]
-id: GO:0052803 ! imidazole-containing compound metabolic process
-is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
-is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
-is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
-
-[Term]
 id: GO:0052805 ! imidazole-containing compound catabolic process
 is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
 is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
@@ -48325,15 +45513,6 @@
 is_a: GO:0072505 {is_inferred="true"} ! divalent inorganic anion homeostasis
 
 [Term]
-id: GO:0055065 ! metal ion homeostasis
-is_a: GO:0098771 {is_inferred="true"} ! inorganic ion homeostasis
-
-[Term]
-id: GO:0055067 ! monovalent inorganic cation homeostasis
-is_a: GO:0055080 {is_inferred="true"} ! cation homeostasis
-is_a: GO:0098771 {is_inferred="true"} ! inorganic ion homeostasis
-
-[Term]
 id: GO:0055068 ! cobalt ion homeostasis
 is_a: GO:0055076 {is_inferred="true"} ! transition metal ion homeostasis
 
@@ -48358,10 +45537,6 @@
 is_a: GO:0055076 {is_inferred="true"} ! transition metal ion homeostasis
 
 [Term]
-id: GO:0055080 ! cation homeostasis
-is_a: GO:0050801 {is_inferred="true"} ! ion homeostasis
-
-[Term]
 id: GO:0055081 ! anion homeostasis
 is_a: GO:0050801 {is_inferred="true"} ! ion homeostasis
 
@@ -48429,17 +45604,6 @@
 is_a: GO:0090504 {is_inferred="true"} ! epiboly
 
 [Term]
-id: GO:0055117 ! regulation of cardiac muscle contraction
-is_a: GO:0006942 {is_inferred="true"} ! regulation of striated muscle contraction
-is_a: GO:0008016 {is_inferred="true"} ! regulation of heart contraction
-
-[Term]
-id: GO:0055118 ! negative regulation of cardiac muscle contraction
-is_a: GO:0045822 {is_inferred="true"} ! negative regulation of heart contraction
-is_a: GO:0045988 {is_inferred="true"} ! negative regulation of striated muscle contraction
-is_a: GO:0055117 {is_inferred="true"} ! regulation of cardiac muscle contraction
-
-[Term]
 id: GO:0055129 ! L-proline biosynthetic process
 is_a: GO:0006561 {is_inferred="true"} ! proline biosynthetic process
 
@@ -48538,14 +45702,6 @@
 is_a: GO:0045104 {is_inferred="true"} ! intermediate filament cytoskeleton organization
 
 [Term]
-id: GO:0060054 ! positive regulation of epithelial cell proliferation involved in wound healing
-is_a: GO:0050679 {is_inferred="true"} ! positive regulation of epithelial cell proliferation
-
-[Term]
-id: GO:0060055 ! angiogenesis involved in wound healing
-is_a: GO:0001525 {is_inferred="true"} ! angiogenesis
-
-[Term]
 id: GO:0060057 ! apoptotic process involved in mammary gland involution
 is_a: GO:0060561 {is_inferred="true"} ! apoptotic process involved in morphogenesis
 
@@ -48638,10 +45794,6 @@
 is_a: GO:0002068 {is_inferred="true"} ! glandular epithelial cell development
 
 [Term]
-id: GO:0060136 ! embryonic process involved in female pregnancy
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-
-[Term]
 id: GO:0060142 ! regulation of syncytium formation by plasma membrane fusion
 is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
 
@@ -48883,10 +46035,6 @@
 is_a: GO:1903059 {is_inferred="true"} ! regulation of protein lipidation
 
 [Term]
-id: GO:0060255 ! regulation of macromolecule metabolic process
-is_a: GO:0019222 {is_inferred="true"} ! regulation of metabolic process
-
-[Term]
 id: GO:0060256 ! regulation of flocculation
 is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 
@@ -48901,10 +46049,6 @@
 is_a: GO:0045926 {is_inferred="true"} ! negative regulation of growth
 
 [Term]
-id: GO:0060259 ! regulation of feeding behavior
-is_a: GO:0050795 {is_inferred="true"} ! regulation of behavior
-
-[Term]
 id: GO:0060260 ! regulation of transcription initiation from RNA polymerase II promoter
 is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
 is_a: GO:2000142 {is_inferred="true"} ! regulation of DNA-templated transcription, initiation
@@ -49003,10 +46147,6 @@
 is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
 
 [Term]
-id: GO:0060284 ! regulation of cell development
-is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
-
-[Term]
 id: GO:0060287 ! epithelial cilium movement involved in determination of left/right asymmetry
 is_a: GO:0003351 {is_inferred="true"} ! epithelial cilium movement
 
@@ -49177,18 +46317,6 @@
 is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
 
 [Term]
-id: GO:0060348 ! bone development
-is_a: GO:0048513 {is_inferred="true"} ! animal organ development
-
-[Term]
-id: GO:0060349 ! bone morphogenesis
-is_a: GO:0009887 {is_inferred="true"} ! animal organ morphogenesis
-
-[Term]
-id: GO:0060351 ! cartilage development involved in endochondral bone morphogenesis
-is_a: GO:0051216 {is_inferred="true"} ! cartilage development
-
-[Term]
 id: GO:0060353 ! regulation of cell adhesion molecule production
 is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
 
@@ -49337,24 +46465,6 @@
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
 
 [Term]
-id: GO:0060405 ! regulation of penile erection
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
-is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
-is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
-
-[Term]
-id: GO:0060406 ! positive regulation of penile erection
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
-is_a: GO:0060405 {is_inferred="true"} ! regulation of penile erection
-is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
-
-[Term]
-id: GO:0060407 ! negative regulation of penile erection
-is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
-is_a: GO:0060405 {is_inferred="true"} ! regulation of penile erection
-is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
-
-[Term]
 id: GO:0060408 ! regulation of acetylcholine metabolic process
 is_a: GO:0001505 {is_inferred="true"} ! regulation of neurotransmitter levels
 
@@ -49425,39 +46535,6 @@
 is_a: GO:0060457 {is_inferred="true"} ! negative regulation of digestive system process
 
 [Term]
-id: GO:0060452 ! positive regulation of cardiac muscle contraction
-is_a: GO:0045823 {is_inferred="true"} ! positive regulation of heart contraction
-is_a: GO:0045989 {is_inferred="true"} ! positive regulation of striated muscle contraction
-is_a: GO:0055117 {is_inferred="true"} ! regulation of cardiac muscle contraction
-
-[Term]
-id: GO:0060453 ! regulation of gastric acid secretion
-is_a: GO:0044058 {is_inferred="true"} ! regulation of digestive system process
-is_a: GO:0051046 {is_inferred="true"} ! regulation of secretion
-
-[Term]
-id: GO:0060454 ! positive regulation of gastric acid secretion
-is_a: GO:0051047 {is_inferred="true"} ! positive regulation of secretion
-is_a: GO:0060453 {is_inferred="true"} ! regulation of gastric acid secretion
-is_a: GO:0060456 {is_inferred="true"} ! positive regulation of digestive system process
-
-[Term]
-id: GO:0060455 ! negative regulation of gastric acid secretion
-is_a: GO:0051048 {is_inferred="true"} ! negative regulation of secretion
-is_a: GO:0060453 {is_inferred="true"} ! regulation of gastric acid secretion
-is_a: GO:0060457 {is_inferred="true"} ! negative regulation of digestive system process
-
-[Term]
-id: GO:0060456 ! positive regulation of digestive system process
-is_a: GO:0044058 {is_inferred="true"} ! regulation of digestive system process
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-
-[Term]
-id: GO:0060457 ! negative regulation of digestive system process
-is_a: GO:0044058 {is_inferred="true"} ! regulation of digestive system process
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-
-[Term]
 id: GO:0060466 ! activation of meiosis involved in egg activation
 is_a: GO:0022414 {is_inferred="true"} ! reproductive process
 is_a: GO:0090427 {is_inferred="true"} ! activation of meiosis
@@ -49493,11 +46570,6 @@
 is_a: GO:1905516 {is_inferred="true"} ! positive regulation of fertilization
 
 [Term]
-id: GO:0060474 ! positive regulation of flagellated sperm motility involved in capacitation
-is_a: GO:0022414 {is_inferred="true"} ! reproductive process
-is_a: GO:1902093 {is_inferred="true"} ! positive regulation of flagellated sperm motility
-
-[Term]
 id: GO:0060475 ! positive regulation of actin filament polymerization involved in acrosome reaction
 is_a: GO:0030838 {is_inferred="true"} ! positive regulation of actin filament polymerization
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
@@ -49726,10 +46798,6 @@
 is_a: GO:1902932 {is_inferred="true"} ! positive regulation of alcohol biosynthetic process
 
 [Term]
-id: GO:0060560 ! developmental growth involved in morphogenesis
-is_a: GO:0048589 {is_inferred="true"} ! developmental growth
-
-[Term]
 id: GO:0060563 ! neuroepithelial cell differentiation
 is_a: GO:0002065 {is_inferred="true"} ! columnar/cuboidal epithelial cell differentiation
 
@@ -49879,10 +46947,6 @@
 is_a: GO:0060625 {is_inferred="true"} ! regulation of protein deneddylation
 
 [Term]
-id: GO:0060627 ! regulation of vesicle-mediated transport
-is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
-
-[Term]
 id: GO:0060628 ! regulation of ER to Golgi vesicle-mediated transport
 is_a: GO:0032386 {is_inferred="true"} ! regulation of intracellular transport
 is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
@@ -50055,11 +47119,6 @@
 is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
 
 [Term]
-id: GO:0060688 ! regulation of morphogenesis of a branching structure
-is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
-is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
-
-[Term]
 id: GO:0060689 ! cell differentiation involved in salivary gland development
 is_a: GO:0030154 {is_inferred="true"} ! cell differentiation
 
@@ -50333,10 +47392,6 @@
 is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 
 [Term]
-id: GO:0060764 ! cell-cell signaling involved in mammary gland development
-is_a: GO:0007267 {is_inferred="true"} ! cell-cell signaling
-
-[Term]
 id: GO:0060765 ! regulation of androgen receptor signaling pathway
 is_a: GO:0033143 {is_inferred="true"} ! regulation of intracellular steroid hormone receptor signaling pathway
 
@@ -50827,34 +47882,10 @@
 is_a: GO:0030855 {is_inferred="true"} ! epithelial cell differentiation
 
 [Term]
-id: GO:0061024 ! membrane organization
-is_a: GO:0016043 {is_inferred="true"} ! cellular component organization
-
-[Term]
-id: GO:0061035 ! regulation of cartilage development
-is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
-
-[Term]
-id: GO:0061036 ! positive regulation of cartilage development
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-is_a: GO:0061035 {is_inferred="true"} ! regulation of cartilage development
-
-[Term]
-id: GO:0061037 ! negative regulation of cartilage development
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-is_a: GO:0061035 {is_inferred="true"} ! regulation of cartilage development
-
-[Term]
 id: GO:0061038 ! uterus morphogenesis
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 
 [Term]
-id: GO:0061041 ! regulation of wound healing
-is_a: GO:1903034 {is_inferred="true"} ! regulation of response to wounding
-
-[Term]
 id: GO:0061043 ! regulation of vascular wound healing
 is_a: GO:0045765 {is_inferred="true"} ! regulation of angiogenesis
 is_a: GO:0061041 {is_inferred="true"} ! regulation of wound healing
@@ -50865,11 +47896,6 @@
 is_a: GO:0061043 {is_inferred="true"} ! regulation of vascular wound healing
 
 [Term]
-id: GO:0061045 ! negative regulation of wound healing
-is_a: GO:0061041 {is_inferred="true"} ! regulation of wound healing
-is_a: GO:1903035 {is_inferred="true"} ! negative regulation of response to wounding
-
-[Term]
 id: GO:0061046 ! regulation of branching involved in lung morphogenesis
 is_a: GO:0060688 {is_inferred="true"} ! regulation of morphogenesis of a branching structure
 is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
@@ -50935,20 +47961,6 @@
 is_a: GO:1900425 {is_inferred="true"} ! negative regulation of defense response to bacterium
 
 [Term]
-id: GO:0061062 ! regulation of nematode larval development
-is_a: GO:0048580 {is_inferred="true"} ! regulation of post-embryonic development
-
-[Term]
-id: GO:0061063 ! positive regulation of nematode larval development
-is_a: GO:0048582 {is_inferred="true"} ! positive regulation of post-embryonic development
-is_a: GO:0061062 {is_inferred="true"} ! regulation of nematode larval development
-
-[Term]
-id: GO:0061064 ! negative regulation of nematode larval development
-is_a: GO:0048581 {is_inferred="true"} ! negative regulation of post-embryonic development
-is_a: GO:0061062 {is_inferred="true"} ! regulation of nematode larval development
-
-[Term]
 id: GO:0061065 ! regulation of dauer larval development
 is_a: GO:0061062 {is_inferred="true"} ! regulation of nematode larval development
 
@@ -51205,17 +48217,6 @@
 is_a: GO:0061178 {is_inferred="true"} ! regulation of insulin secretion involved in cellular response to glucose stimulus
 
 [Term]
-id: GO:0061181 ! regulation of chondrocyte development
-is_a: GO:0032330 {is_inferred="true"} ! regulation of chondrocyte differentiation
-is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
-
-[Term]
-id: GO:0061182 ! negative regulation of chondrocyte development
-is_a: GO:0010721 {is_inferred="true"} ! negative regulation of cell development
-is_a: GO:0032331 {is_inferred="true"} ! negative regulation of chondrocyte differentiation
-is_a: GO:0061181 {is_inferred="true"} ! regulation of chondrocyte development
-
-[Term]
 id: GO:0061183 ! regulation of dermatome development
 is_a: GO:0045995 {is_inferred="true"} ! regulation of embryonic development
 
@@ -52046,10 +49047,6 @@
 is_a: GO:0065003 {is_inferred="true"} ! macromolecular complex assembly
 
 [Term]
-id: GO:0065009 ! regulation of molecular function
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
-
-[Term]
 id: GO:0070013 ! intracellular organelle lumen
 is_a: GO:0043233 {is_inferred="true"} ! organelle lumen
 is_a: GO:0044424 {is_inferred="true"} ! intracellular part
@@ -52132,20 +49129,6 @@
 is_a: GO:0015031 {is_inferred="true"} ! protein transport
 
 [Term]
-id: GO:0070092 ! regulation of glucagon secretion
-is_a: GO:0090276 {is_inferred="true"} ! regulation of peptide hormone secretion
-
-[Term]
-id: GO:0070093 ! negative regulation of glucagon secretion
-is_a: GO:0070092 {is_inferred="true"} ! regulation of glucagon secretion
-is_a: GO:0090278 {is_inferred="true"} ! negative regulation of peptide hormone secretion
-
-[Term]
-id: GO:0070094 ! positive regulation of glucagon secretion
-is_a: GO:0070092 {is_inferred="true"} ! regulation of glucagon secretion
-is_a: GO:0090277 {is_inferred="true"} ! positive regulation of peptide hormone secretion
-
-[Term]
 id: GO:0070095 ! fructose-6-phosphate binding
 is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
@@ -52352,20 +49335,6 @@
 is_a: GO:0070163 {is_inferred="true"} ! regulation of adiponectin secretion
 
 [Term]
-id: GO:0070167 ! regulation of biomineral tissue development
-is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
-
-[Term]
-id: GO:0070168 ! negative regulation of biomineral tissue development
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
-is_a: GO:0070167 {is_inferred="true"} ! regulation of biomineral tissue development
-
-[Term]
-id: GO:0070169 ! positive regulation of biomineral tissue development
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
-is_a: GO:0070167 {is_inferred="true"} ! regulation of biomineral tissue development
-
-[Term]
 id: GO:0070170 ! regulation of tooth mineralization
 is_a: GO:0042481 {is_inferred="true"} ! regulation of odontogenesis
 is_a: GO:0070167 {is_inferred="true"} ! regulation of biomineral tissue development
@@ -52441,10 +49410,6 @@
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
-id: GO:0070201 ! regulation of establishment of protein localization
-is_a: GO:0032880 {is_inferred="true"} ! regulation of protein localization
-
-[Term]
 id: GO:0070202 ! regulation of establishment of protein localization to chromosome
 is_a: GO:0070201 {is_inferred="true"} ! regulation of establishment of protein localization
 is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
@@ -52560,24 +49525,6 @@
 is_a: GO:0070247 {is_inferred="true"} ! regulation of natural killer cell apoptotic process
 
 [Term]
-id: GO:0070255 ! regulation of mucus secretion
-is_a: GO:0050878 {is_inferred="true"} ! regulation of body fluid levels
-is_a: GO:0051046 {is_inferred="true"} ! regulation of secretion
-is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
-
-[Term]
-id: GO:0070256 ! negative regulation of mucus secretion
-is_a: GO:0051048 {is_inferred="true"} ! negative regulation of secretion
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-is_a: GO:0070255 {is_inferred="true"} ! regulation of mucus secretion
-
-[Term]
-id: GO:0070257 ! positive regulation of mucus secretion
-is_a: GO:0051047 {is_inferred="true"} ! positive regulation of secretion
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-is_a: GO:0070255 {is_inferred="true"} ! regulation of mucus secretion
-
-[Term]
 id: GO:0070264 ! transcription factor TFIIIE complex
 is_a: GO:0044451 {is_inferred="true"} ! nucleoplasm part
 
@@ -53022,10 +49969,6 @@
 is_a: GO:0070486 {is_inferred="true"} ! leukocyte aggregation
 
 [Term]
-id: GO:0070489 ! T cell aggregation
-is_a: GO:0045321 {is_inferred="true"} ! leukocyte activation
-
-[Term]
 id: GO:0070492 ! oligosaccharide binding
 is_a: GO:0030246 {is_inferred="true"} ! carbohydrate binding
 
@@ -53130,6 +50073,10 @@
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
 [Term]
+id: GO:0070560 ! protein secretion by platelet
+is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
+
+[Term]
 id: GO:0070562 ! regulation of vitamin D receptor signaling pathway
 is_a: GO:0009966 {is_inferred="true"} ! regulation of signal transduction
 is_a: GO:0032107 {is_inferred="true"} ! regulation of response to nutrient levels
@@ -53372,20 +50319,6 @@
 is_a: GO:0070656 {is_inferred="true"} ! mechanoreceptor differentiation involved in mechanosensory epithelium regeneration
 
 [Term]
-id: GO:0070663 ! regulation of leukocyte proliferation
-is_a: GO:0042127 {is_inferred="true"} ! regulation of cell proliferation
-
-[Term]
-id: GO:0070664 ! negative regulation of leukocyte proliferation
-is_a: GO:0008285 {is_inferred="true"} ! negative regulation of cell proliferation
-is_a: GO:0070663 {is_inferred="true"} ! regulation of leukocyte proliferation
-
-[Term]
-id: GO:0070665 ! positive regulation of leukocyte proliferation
-is_a: GO:0008284 {is_inferred="true"} ! positive regulation of cell proliferation
-is_a: GO:0070663 {is_inferred="true"} ! regulation of leukocyte proliferation
-
-[Term]
 id: GO:0070666 ! regulation of mast cell proliferation
 is_a: GO:0070663 {is_inferred="true"} ! regulation of leukocyte proliferation
 
@@ -53732,26 +50665,6 @@
 is_a: GO:0030001 {is_inferred="true"} ! metal ion transport
 
 [Term]
-id: GO:0070857 ! regulation of bile acid biosynthetic process
-is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
-is_a: GO:0050810 {is_inferred="true"} ! regulation of steroid biosynthetic process
-is_a: GO:1904251 {is_inferred="true"} ! regulation of bile acid metabolic process
-
-[Term]
-id: GO:0070858 ! negative regulation of bile acid biosynthetic process
-is_a: GO:0010894 {is_inferred="true"} ! negative regulation of steroid biosynthetic process
-is_a: GO:0031327 {is_inferred="true"} ! negative regulation of cellular biosynthetic process
-is_a: GO:0070857 {is_inferred="true"} ! regulation of bile acid biosynthetic process
-is_a: GO:1904252 {is_inferred="true"} ! negative regulation of bile acid metabolic process
-
-[Term]
-id: GO:0070859 ! positive regulation of bile acid biosynthetic process
-is_a: GO:0010893 {is_inferred="true"} ! positive regulation of steroid biosynthetic process
-is_a: GO:0031328 {is_inferred="true"} ! positive regulation of cellular biosynthetic process
-is_a: GO:0070857 {is_inferred="true"} ! regulation of bile acid biosynthetic process
-is_a: GO:1904253 {is_inferred="true"} ! positive regulation of bile acid metabolic process
-
-[Term]
 id: GO:0070861 ! regulation of protein exit from endoplasmic reticulum
 is_a: GO:0033157 {is_inferred="true"} ! regulation of intracellular protein transport
 
@@ -53790,22 +50703,6 @@
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 
 [Term]
-id: GO:0070873 ! regulation of glycogen metabolic process
-is_a: GO:0032881 {is_inferred="true"} ! regulation of polysaccharide metabolic process
-is_a: GO:0043467 {is_inferred="true"} ! regulation of generation of precursor metabolites and energy
-
-[Term]
-id: GO:0070874 ! negative regulation of glycogen metabolic process
-is_a: GO:0010605 {is_inferred="true"} ! negative regulation of macromolecule metabolic process
-is_a: GO:0010677 {is_inferred="true"} ! negative regulation of cellular carbohydrate metabolic process
-is_a: GO:0070873 {is_inferred="true"} ! regulation of glycogen metabolic process
-
-[Term]
-id: GO:0070875 ! positive regulation of glycogen metabolic process
-is_a: GO:0010604 {is_inferred="true"} ! positive regulation of macromolecule metabolic process
-is_a: GO:0070873 {is_inferred="true"} ! regulation of glycogen metabolic process
-
-[Term]
 id: GO:0070881 ! regulation of proline transport
 is_a: GO:0051955 {is_inferred="true"} ! regulation of amino acid transport
 
@@ -55561,10 +52458,6 @@
 is_a: GO:0071591 {is_inferred="true"} ! nicotinic acid riboside metabolic process
 
 [Term]
-id: GO:0071593 ! lymphocyte aggregation
-is_a: GO:0070486 {is_inferred="true"} ! leukocyte aggregation
-
-[Term]
 id: GO:0071598 ! neuronal ribonucleoprotein granule
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
 
@@ -55816,18 +52709,6 @@
 is_a: GO:0046825 {is_inferred="true"} ! regulation of protein export from nucleus
 
 [Term]
-id: GO:0071702 ! organic substance transport
-is_a: GO:0006810 {is_inferred="true"} ! transport
-
-[Term]
-id: GO:0071704 ! organic substance metabolic process
-is_a: GO:0008152 {is_inferred="true"} ! metabolic process
-
-[Term]
-id: GO:0071705 ! nitrogen compound transport
-is_a: GO:0006810 {is_inferred="true"} ! transport
-
-[Term]
 id: GO:0071715 ! icosanoid transport
 is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
 is_a: GO:1901571 {is_inferred="true"} ! fatty acid derivative transport
@@ -56596,11 +53477,6 @@
 is_a: GO:0072201 {is_inferred="true"} ! negative regulation of mesenchymal cell proliferation
 
 [Term]
-id: GO:0072201 ! negative regulation of mesenchymal cell proliferation
-is_a: GO:0008285 {is_inferred="true"} ! negative regulation of cell proliferation
-is_a: GO:0010464 {is_inferred="true"} ! regulation of mesenchymal cell proliferation
-
-[Term]
 id: GO:0072202 ! cell differentiation involved in metanephros development
 is_a: GO:0061005 {is_inferred="true"} ! cell differentiation involved in kidney development
 
@@ -56822,11 +53698,6 @@
 is_a: GO:0046395 {is_inferred="true"} ! carboxylic acid catabolic process
 
 [Term]
-id: GO:0072330 ! monocarboxylic acid biosynthetic process
-is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
-is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
-
-[Term]
 id: GO:0072334 ! UDP-galactose transmembrane transport
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
@@ -57186,10 +54057,6 @@
 is_a: GO:0098771 {is_inferred="true"} ! inorganic ion homeostasis
 
 [Term]
-id: GO:0072507 ! divalent inorganic cation homeostasis
-is_a: GO:0098771 {is_inferred="true"} ! inorganic ion homeostasis
-
-[Term]
 id: GO:0072508 ! trivalent inorganic cation homeostasis
 is_a: GO:0098771 {is_inferred="true"} ! inorganic ion homeostasis
 
@@ -58381,10 +55248,6 @@
 is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
 
 [Term]
-id: GO:0080090 ! regulation of primary metabolic process
-is_a: GO:0019222 {is_inferred="true"} ! regulation of metabolic process
-
-[Term]
 id: GO:0080091 ! regulation of raffinose metabolic process
 is_a: GO:0006109 {is_inferred="true"} ! regulation of carbohydrate metabolic process
 
@@ -58455,10 +55318,6 @@
 is_a: GO:1905328 {is_inferred="true"} ! plant septum development
 
 [Term]
-id: GO:0080134 ! regulation of response to stress
-is_a: GO:0048583 {is_inferred="true"} ! regulation of response to stimulus
-
-[Term]
 id: GO:0080135 ! regulation of cellular response to stress
 is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
 is_a: GO:0080134 {is_inferred="true"} ! regulation of response to stress
@@ -59074,7 +55933,6 @@
 [Term]
 id: GO:0090068 ! positive regulation of cell cycle process
 is_a: GO:0010564 {is_inferred="true"} ! regulation of cell cycle process
-is_a: GO:0045787 {is_inferred="true"} ! positive regulation of cell cycle
 
 [Term]
 id: GO:0090069 ! regulation of ribosome biogenesis
@@ -59131,10 +55989,6 @@
 is_a: GO:1903321 {is_inferred="true"} ! negative regulation of protein modification by small protein conjugation or removal
 
 [Term]
-id: GO:0090087 ! regulation of peptide transport
-is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
-
-[Term]
 id: GO:0090088 ! regulation of oligopeptide transport
 is_a: GO:0090087 {is_inferred="true"} ! regulation of peptide transport
 
@@ -59390,11 +56244,6 @@
 is_a: GO:0060629 {is_inferred="true"} ! regulation of homologous chromosome segregation
 
 [Term]
-id: GO:0090174 ! organelle membrane fusion
-is_a: GO:0048284 {is_inferred="true"} ! organelle fusion
-is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
-
-[Term]
 id: GO:0090175 ! regulation of establishment of planar polarity
 is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 
@@ -59747,10 +56596,6 @@
 is_a: GO:2000027 {is_inferred="true"} ! regulation of organ morphogenesis
 
 [Term]
-id: GO:0090257 ! regulation of muscle system process
-is_a: GO:0044057 {is_inferred="true"} ! regulation of system process
-
-[Term]
 id: GO:0090258 ! negative regulation of mitochondrial fission
 is_a: GO:0010823 {is_inferred="true"} ! negative regulation of mitochondrion organization
 is_a: GO:0090140 {is_inferred="true"} ! regulation of mitochondrial fission
@@ -59814,37 +56659,6 @@
 is_a: GO:0090270 {is_inferred="true"} ! regulation of fibroblast growth factor production
 
 [Term]
-id: GO:0090273 ! regulation of somatostatin secretion
-is_a: GO:0090276 {is_inferred="true"} ! regulation of peptide hormone secretion
-
-[Term]
-id: GO:0090274 ! positive regulation of somatostatin secretion
-is_a: GO:0090273 {is_inferred="true"} ! regulation of somatostatin secretion
-is_a: GO:0090277 {is_inferred="true"} ! positive regulation of peptide hormone secretion
-
-[Term]
-id: GO:0090275 ! negative regulation of somatostatin secretion
-is_a: GO:0090273 {is_inferred="true"} ! regulation of somatostatin secretion
-is_a: GO:0090278 {is_inferred="true"} ! negative regulation of peptide hormone secretion
-
-[Term]
-id: GO:0090276 ! regulation of peptide hormone secretion
-is_a: GO:0002791 {is_inferred="true"} ! regulation of peptide secretion
-is_a: GO:0046883 {is_inferred="true"} ! regulation of hormone secretion
-
-[Term]
-id: GO:0090277 ! positive regulation of peptide hormone secretion
-is_a: GO:0002793 {is_inferred="true"} ! positive regulation of peptide secretion
-is_a: GO:0046887 {is_inferred="true"} ! positive regulation of hormone secretion
-is_a: GO:0090276 {is_inferred="true"} ! regulation of peptide hormone secretion
-
-[Term]
-id: GO:0090278 ! negative regulation of peptide hormone secretion
-is_a: GO:0002792 {is_inferred="true"} ! negative regulation of peptide secretion
-is_a: GO:0046888 {is_inferred="true"} ! negative regulation of hormone secretion
-is_a: GO:0090276 {is_inferred="true"} ! regulation of peptide hormone secretion
-
-[Term]
 id: GO:0090279 ! regulation of calcium ion import
 is_a: GO:0051924 {is_inferred="true"} ! regulation of calcium ion transport
 
@@ -59945,11 +56759,6 @@
 is_a: GO:0090299 {is_inferred="true"} ! regulation of neural crest formation
 
 [Term]
-id: GO:0090303 ! positive regulation of wound healing
-is_a: GO:0061041 {is_inferred="true"} ! regulation of wound healing
-is_a: GO:1903036 {is_inferred="true"} ! positive regulation of response to wounding
-
-[Term]
 id: GO:0090304 ! nucleic acid metabolic process
 is_a: GO:0006139 {is_inferred="true"} ! nucleobase-containing compound metabolic process
 is_a: GO:0043170 {is_inferred="true"} ! macromolecule metabolic process
@@ -60057,29 +56866,6 @@
 is_a: GO:1903579 {is_inferred="true"} ! negative regulation of ATP metabolic process
 
 [Term]
-id: GO:0090325 ! regulation of locomotion involved in locomotory behavior
-is_a: GO:0040012 {is_inferred="true"} ! regulation of locomotion
-is_a: GO:0050795 {is_inferred="true"} ! regulation of behavior
-
-[Term]
-id: GO:0090326 ! positive regulation of locomotion involved in locomotory behavior
-is_a: GO:0040017 {is_inferred="true"} ! positive regulation of locomotion
-is_a: GO:0048520 {is_inferred="true"} ! positive regulation of behavior
-is_a: GO:0090325 {is_inferred="true"} ! regulation of locomotion involved in locomotory behavior
-
-[Term]
-id: GO:0090327 ! negative regulation of locomotion involved in locomotory behavior
-is_a: GO:0040013 {is_inferred="true"} ! negative regulation of locomotion
-is_a: GO:0048521 {is_inferred="true"} ! negative regulation of behavior
-is_a: GO:0090325 {is_inferred="true"} ! regulation of locomotion involved in locomotory behavior
-
-[Term]
-id: GO:0090328 ! regulation of olfactory learning
-is_a: GO:0031644 {is_inferred="true"} ! regulation of neurological system process
-is_a: GO:0048583 {is_inferred="true"} ! regulation of response to stimulus
-is_a: GO:0050795 {is_inferred="true"} ! regulation of behavior
-
-[Term]
 id: GO:0090329 ! regulation of DNA-dependent DNA replication
 is_a: GO:0006275 {is_inferred="true"} ! regulation of DNA replication
 
@@ -60775,10 +57561,6 @@
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 
 [Term]
-id: GO:0097164 ! ammonium ion metabolic process
-is_a: GO:0006807 {is_inferred="true"} ! nitrogen compound metabolic process
-
-[Term]
 id: GO:0097170 ! ADP-L-glycero-beta-D-manno-heptose metabolic process
 is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
 is_a: GO:0009225 {is_inferred="true"} ! nucleotide-sugar metabolic process
@@ -61280,10 +58062,6 @@
 is_a: GO:0043229 {is_inferred="true"} ! intracellular organelle
 
 [Term]
-id: GO:0097733 ! photoreceptor cell cilium
-is_a: GO:0097458 {is_inferred="true"} ! neuron part
-
-[Term]
 id: GO:0097740 ! paraflagellar rod
 is_a: GO:0044441 {is_inferred="true"} ! ciliary part
 
@@ -61566,10 +58344,6 @@
 is_a: GO:0044425 {is_inferred="true"} ! membrane part
 
 [Term]
-id: GO:0098590 ! plasma membrane region
-is_a: GO:0044459 {is_inferred="true"} ! plasma membrane part
-
-[Term]
 id: GO:0098592 ! cytoplasmic side of apical plasma membrane
 is_a: GO:0009898 {is_inferred="true"} ! cytoplasmic side of plasma membrane
 
@@ -61579,10 +58353,6 @@
 is_a: GO:0044444 {is_inferred="true"} ! cytoplasmic part
 
 [Term]
-id: GO:0098602 ! single organism cell adhesion
-is_a: GO:0044699 {is_inferred="true"} ! single-organism process
-
-[Term]
 id: GO:0098610 ! adhesion between unicellular organisms
 is_a: GO:0098740 {is_inferred="true"} ! multi organism cell adhesion
 
@@ -61635,22 +58405,10 @@
 is_a: GO:0098632 {is_inferred="true"} ! protein binding involved in cell-cell adhesion
 
 [Term]
-id: GO:0098642 ! network-forming collagen trimer
-is_a: GO:0044420 {is_inferred="true"} ! extracellular matrix component
-
-[Term]
-id: GO:0098644 ! complex of collagen trimers
-is_a: GO:0044420 {is_inferred="true"} ! extracellular matrix component
-
-[Term]
 id: GO:0098649 ! response to peptidyl-dipeptidase A inhibitor
 is_a: GO:0042493 {is_inferred="true"} ! response to drug
 
 [Term]
-id: GO:0098651 ! basement membrane collagen trimer
-is_a: GO:0044420 {is_inferred="true"} ! extracellular matrix component
-
-[Term]
 id: GO:0098655 ! cation transmembrane transport
 is_a: GO:0006812 {is_inferred="true"} ! cation transport
 is_a: GO:0034220 {is_inferred="true"} ! ion transmembrane transport
@@ -61871,10 +58629,6 @@
 is_a: GO:0046658 {is_inferred="true"} ! anchored component of plasma membrane
 
 [Term]
-id: GO:0098771 ! inorganic ion homeostasis
-is_a: GO:0050801 {is_inferred="true"} ! ion homeostasis
-
-[Term]
 id: GO:0098773 ! skin epidermis development
 is_a: GO:0060429 {is_inferred="true"} ! epithelium development
 
@@ -61934,15 +58688,6 @@
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
 
 [Term]
-id: GO:0098796 ! membrane protein complex
-is_a: GO:0044425 {is_inferred="true"} ! membrane part
-
-[Term]
-id: GO:0098797 ! plasma membrane protein complex
-is_a: GO:0044459 {is_inferred="true"} ! plasma membrane part
-is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
-
-[Term]
 id: GO:0098798 ! mitochondrial protein complex
 is_a: GO:0044429 {is_inferred="true"} ! mitochondrial part
 
@@ -61959,10 +58704,6 @@
 is_a: GO:0098798 {is_inferred="true"} ! mitochondrial protein complex
 
 [Term]
-id: GO:0098801 ! regulation of renal system process
-is_a: GO:0044057 {is_inferred="true"} ! regulation of system process
-
-[Term]
 id: GO:0098802 ! plasma membrane receptor complex
 is_a: GO:0043235 {is_inferred="true"} ! receptor complex
 is_a: GO:0044459 {is_inferred="true"} ! plasma membrane part
@@ -63037,11 +59778,6 @@
 is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
 
 [Term]
-id: GO:0099500 ! vesicle fusion to plasma membrane
-is_a: GO:0006906 {is_inferred="true"} ! vesicle fusion
-is_a: GO:0045026 {is_inferred="true"} ! plasma membrane fusion
-
-[Term]
 id: GO:0099501 ! exocytic vesicle membrane
 is_a: GO:0030658 {is_inferred="true"} ! transport vesicle membrane
 
@@ -63064,11 +59800,6 @@
 is_a: GO:0070050 {is_inferred="true"} ! neuron cellular homeostasis
 
 [Term]
-id: GO:0099513 ! polymeric cytoskeletal fiber
-is_a: GO:0044430 {is_inferred="true"} ! cytoskeletal part
-is_a: GO:0099512 {is_inferred="true"} ! supramolecular fiber
-
-[Term]
 id: GO:0099514 ! synaptic vesicle cytoskeletal transport
 is_a: GO:0048489 {is_inferred="true"} ! synaptic vesicle transport
 is_a: GO:0099518 {is_inferred="true"} ! vesicle cytoskeletal trafficking
@@ -63317,8 +60048,13 @@
 is_a: GO:0098576 {is_inferred="true"} ! lumenal side of membrane
 
 [Term]
+id: GO:0099622 ! cardiac muscle cell membrane repolarization
+is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
+
+[Term]
 id: GO:0099623 ! regulation of cardiac muscle cell membrane repolarization
 is_a: GO:0060306 {is_inferred="true"} ! regulation of membrane repolarization
+is_a: GO:0060341 {is_inferred="true"} ! regulation of cellular localization
 
 [Term]
 id: GO:0099624 ! atrial cardiac muscle cell membrane repolarization
@@ -63990,21 +60726,6 @@
 is_a: GO:1902915 {is_inferred="true"} ! negative regulation of protein polyubiquitination
 
 [Term]
-id: GO:1900046 ! regulation of hemostasis
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0050878 {is_inferred="true"} ! regulation of body fluid levels
-
-[Term]
-id: GO:1900047 ! negative regulation of hemostasis
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
-is_a: GO:1900046 {is_inferred="true"} ! regulation of hemostasis
-
-[Term]
-id: GO:1900048 ! positive regulation of hemostasis
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
-is_a: GO:1900046 {is_inferred="true"} ! regulation of hemostasis
-
-[Term]
 id: GO:1900050 ! negative regulation of histone exchange
 is_a: GO:1900049 {is_inferred="true"} ! regulation of histone exchange
 is_a: GO:1905268 {is_inferred="true"} ! negative regulation of chromatin organization
@@ -64249,26 +60970,6 @@
 is_a: GO:1900095 {is_inferred="true"} ! regulation of dosage compensation by inactivation of X chromosome
 
 [Term]
-id: GO:1900098 ! regulation of plasma cell differentiation
-is_a: GO:0002697 {is_inferred="true"} ! regulation of immune effector process
-is_a: GO:0045577 {is_inferred="true"} ! regulation of B cell differentiation
-is_a: GO:0050776 {is_inferred="true"} ! regulation of immune response
-
-[Term]
-id: GO:1900099 ! negative regulation of plasma cell differentiation
-is_a: GO:0002698 {is_inferred="true"} ! negative regulation of immune effector process
-is_a: GO:0045578 {is_inferred="true"} ! negative regulation of B cell differentiation
-is_a: GO:0050777 {is_inferred="true"} ! negative regulation of immune response
-is_a: GO:1900098 {is_inferred="true"} ! regulation of plasma cell differentiation
-
-[Term]
-id: GO:1900100 ! positive regulation of plasma cell differentiation
-is_a: GO:0002699 {is_inferred="true"} ! positive regulation of immune effector process
-is_a: GO:0045579 {is_inferred="true"} ! positive regulation of B cell differentiation
-is_a: GO:0050778 {is_inferred="true"} ! positive regulation of immune response
-is_a: GO:1900098 {is_inferred="true"} ! regulation of plasma cell differentiation
-
-[Term]
 id: GO:1900101 ! regulation of endoplasmic reticulum unfolded protein response
 is_a: GO:0009966 {is_inferred="true"} ! regulation of signal transduction
 is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
@@ -69789,20 +66490,11 @@
 is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 
 [Term]
-id: GO:1901135 ! carbohydrate derivative metabolic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
-
-[Term]
 id: GO:1901136 ! carbohydrate derivative catabolic process
 is_a: GO:1901135 {is_inferred="true"} ! carbohydrate derivative metabolic process
 is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
 
 [Term]
-id: GO:1901137 ! carbohydrate derivative biosynthetic process
-is_a: GO:1901135 {is_inferred="true"} ! carbohydrate derivative metabolic process
-is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
-
-[Term]
 id: GO:1901140 ! p-coumaryl alcohol transport
 is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
 
@@ -69895,10 +66587,6 @@
 is_a: GO:1901137 {is_inferred="true"} ! carbohydrate derivative biosynthetic process
 
 [Term]
-id: GO:1901160 ! primary amino compound metabolic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
-
-[Term]
 id: GO:1901161 ! primary amino compound catabolic process
 is_a: GO:1901160 {is_inferred="true"} ! primary amino compound metabolic process
 is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
@@ -70681,15 +67369,6 @@
 is_a: GO:1902523 {is_inferred="true"} ! positive regulation of protein K63-linked ubiquitination
 
 [Term]
-id: GO:1901317 ! regulation of flagellated sperm motility
-is_a: GO:2000145 {is_inferred="true"} ! regulation of cell motility
-
-[Term]
-id: GO:1901318 ! negative regulation of flagellated sperm motility
-is_a: GO:1901317 {is_inferred="true"} ! regulation of flagellated sperm motility
-is_a: GO:2000146 {is_inferred="true"} ! negative regulation of cell motility
-
-[Term]
 id: GO:1901319 ! positive regulation of trehalose catabolic process
 is_a: GO:0010676 {is_inferred="true"} ! positive regulation of cellular carbohydrate metabolic process
 is_a: GO:0031331 {is_inferred="true"} ! positive regulation of cellular catabolic process
@@ -70811,16 +67490,6 @@
 is_a: GO:2001259 {is_inferred="true"} ! positive regulation of cation channel activity
 
 [Term]
-id: GO:1901342 ! regulation of vasculature development
-is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
-
-[Term]
-id: GO:1901343 ! negative regulation of vasculature development
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-is_a: GO:1901342 {is_inferred="true"} ! regulation of vasculature development
-
-[Term]
 id: GO:1901344 ! response to leptomycin B
 is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
 is_a: GO:0070542 {is_inferred="true"} ! response to fatty acid
@@ -70900,20 +67569,11 @@
 is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
 [Term]
-id: GO:1901360 ! organic cyclic compound metabolic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
-
-[Term]
 id: GO:1901361 ! organic cyclic compound catabolic process
 is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
 is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
 
 [Term]
-id: GO:1901362 ! organic cyclic compound biosynthetic process
-is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
-is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
-
-[Term]
 id: GO:1901363 ! heterocyclic compound binding
 is_a: GO:0005488 {is_inferred="true"} ! binding
 
@@ -71929,21 +68589,11 @@
 is_a: GO:0097305 {is_inferred="true"} ! response to alcohol
 
 [Term]
-id: GO:1901564 ! organonitrogen compound metabolic process
-is_a: GO:0006807 {is_inferred="true"} ! nitrogen compound metabolic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
-
-[Term]
 id: GO:1901565 ! organonitrogen compound catabolic process
 is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
 is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
 
 [Term]
-id: GO:1901566 ! organonitrogen compound biosynthetic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
-is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
-
-[Term]
 id: GO:1901567 ! fatty acid derivative binding
 is_a: GO:0005488 {is_inferred="true"} ! binding
 
@@ -71968,16 +68618,6 @@
 is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 
 [Term]
-id: GO:1901575 ! organic substance catabolic process
-is_a: GO:0009056 {is_inferred="true"} ! catabolic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
-
-[Term]
-id: GO:1901576 ! organic substance biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
-
-[Term]
 id: GO:1901577 ! regulation of alkane biosynthetic process
 is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
 
@@ -72034,12 +68674,6 @@
 is_a: GO:2001259 {is_inferred="true"} ! positive regulation of cation channel activity
 
 [Term]
-id: GO:1901588 ! dendritic microtubule
-is_a: GO:0005874 {is_inferred="true"} ! microtubule
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
-is_a: GO:0097458 {is_inferred="true"} ! neuron part
-
-[Term]
 id: GO:1901589 ! axon microtubule bundle
 is_a: GO:0033267 {is_inferred="true"} ! axon part
 is_a: GO:0097427 {is_inferred="true"} ! microtubule bundle
@@ -72128,10 +68762,6 @@
 is_a: GO:0042887 {is_inferred="true"} ! amide transmembrane transporter activity
 
 [Term]
-id: GO:1901605 ! alpha-amino acid metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
-
-[Term]
 id: GO:1901606 ! alpha-amino acid catabolic process
 is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
 is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
@@ -72176,20 +68806,11 @@
 is_a: GO:2000331 {is_inferred="true"} ! regulation of terminal button organization
 
 [Term]
-id: GO:1901615 ! organic hydroxy compound metabolic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
-
-[Term]
 id: GO:1901616 ! organic hydroxy compound catabolic process
 is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
 is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
 
 [Term]
-id: GO:1901617 ! organic hydroxy compound biosynthetic process
-is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
-is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
-
-[Term]
 id: GO:1901618 ! organic hydroxy compound transmembrane transporter activity
 is_a: GO:0022857 {is_inferred="true"} ! transmembrane transporter activity
 
@@ -72576,10 +69197,6 @@
 is_a: GO:1901698 {is_inferred="true"} ! response to nitrogen compound
 
 [Term]
-id: GO:1901700 ! response to oxygen-containing compound
-is_a: GO:0042221 {is_inferred="true"} ! response to chemical
-
-[Term]
 id: GO:1901701 ! cellular response to oxygen-containing compound
 is_a: GO:0070887 {is_inferred="true"} ! cellular response to chemical stimulus
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
@@ -74641,11 +71258,6 @@
 is_a: GO:1902090 {is_inferred="true"} ! regulation of fumagillin biosynthetic process
 
 [Term]
-id: GO:1902093 ! positive regulation of flagellated sperm motility
-is_a: GO:1901317 {is_inferred="true"} ! regulation of flagellated sperm motility
-is_a: GO:2000147 {is_inferred="true"} ! positive regulation of cell motility
-
-[Term]
 id: GO:1902094 ! regulation of cartilage homeostasis
 is_a: GO:0032844 {is_inferred="true"} ! regulation of homeostatic process
 is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
@@ -74703,23 +71315,6 @@
 is_a: GO:1902102 {is_inferred="true"} ! regulation of metaphase/anaphase transition of meiotic cell cycle
 
 [Term]
-id: GO:1902105 ! regulation of leukocyte differentiation
-is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
-is_a: GO:1903706 {is_inferred="true"} ! regulation of hemopoiesis
-
-[Term]
-id: GO:1902106 ! negative regulation of leukocyte differentiation
-is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
-is_a: GO:1902105 {is_inferred="true"} ! regulation of leukocyte differentiation
-is_a: GO:1903707 {is_inferred="true"} ! negative regulation of hemopoiesis
-
-[Term]
-id: GO:1902107 ! positive regulation of leukocyte differentiation
-is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
-is_a: GO:1902105 {is_inferred="true"} ! regulation of leukocyte differentiation
-is_a: GO:1903708 {is_inferred="true"} ! positive regulation of hemopoiesis
-
-[Term]
 id: GO:1902108 ! regulation of mitochondrial membrane permeability involved in apoptotic process
 is_a: GO:0046902 {is_inferred="true"} ! regulation of mitochondrial membrane permeability
 
@@ -76544,33 +73139,6 @@
 is_a: GO:1904019 {is_inferred="true"} ! epithelial cell apoptotic process
 
 [Term]
-id: GO:1902490 ! regulation of sperm capacitation
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
-is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
-is_a: GO:1903429 {is_inferred="true"} ! regulation of cell maturation
-is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
-
-[Term]
-id: GO:1902491 ! negative regulation of sperm capacitation
-is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-is_a: GO:1902490 {is_inferred="true"} ! regulation of sperm capacitation
-is_a: GO:1903430 {is_inferred="true"} ! negative regulation of cell maturation
-is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
-
-[Term]
-id: GO:1902492 ! positive regulation of sperm capacitation
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-is_a: GO:1902490 {is_inferred="true"} ! regulation of sperm capacitation
-is_a: GO:1903431 {is_inferred="true"} ! positive regulation of cell maturation
-is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
-
-[Term]
-id: GO:1902494 ! catalytic complex
-is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
-
-[Term]
 id: GO:1902495 ! transmembrane transporter complex
 is_a: GO:0044425 {is_inferred="true"} ! membrane part
 
@@ -76969,11 +73537,6 @@
 is_a: GO:0071574 {is_inferred="true"} ! protein localization to medial cortex
 
 [Term]
-id: GO:1902578 ! single-organism localization
-is_a: GO:0044699 {is_inferred="true"} ! single-organism process
-is_a: GO:0051179 {is_inferred="true"} ! localization
-
-[Term]
 id: GO:1902579 ! multi-organism localization
 is_a: GO:0051179 {is_inferred="true"} ! localization
 is_a: GO:0051704 {is_inferred="true"} ! multi-organism process
@@ -77001,11 +73564,6 @@
 is_a: GO:1902581 {is_inferred="true"} ! multi-organism cellular localization
 
 [Term]
-id: GO:1902584 ! positive regulation of response to water deprivation
-is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
-is_a: GO:2000070 {is_inferred="true"} ! regulation of response to water deprivation
-
-[Term]
 id: GO:1902585 ! single-organism intercellular transport
 is_a: GO:0010496 {is_inferred="true"} ! intercellular transport
 is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
@@ -77028,11 +73586,6 @@
 is_a: GO:1902586 {is_inferred="true"} ! multi-organism intercellular transport
 
 [Term]
-id: GO:1902589 ! single-organism organelle organization
-is_a: GO:0006996 {is_inferred="true"} ! organelle organization
-is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
-
-[Term]
 id: GO:1902590 ! multi-organism organelle organization
 is_a: GO:0006996 {is_inferred="true"} ! organelle organization
 is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
@@ -77721,12 +74274,6 @@
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
 
 [Term]
-id: GO:1902738 ! regulation of chondrocyte differentiation involved in endochondral bone morphogenesis
-is_a: GO:0032330 {is_inferred="true"} ! regulation of chondrocyte differentiation
-is_a: GO:1903010 {is_inferred="true"} ! regulation of bone development
-is_a: GO:2000027 {is_inferred="true"} ! regulation of organ morphogenesis
-
-[Term]
 id: GO:1902739 ! regulation of interferon-alpha secretion
 is_a: GO:0032647 {is_inferred="true"} ! regulation of interferon-alpha production
 is_a: GO:0050707 {is_inferred="true"} ! regulation of cytokine secretion
@@ -77837,12 +74384,6 @@
 is_a: GO:1902759 {is_inferred="true"} ! Mo(VI)-molybdopterin cytosine dinucleotide metabolic process
 
 [Term]
-id: GO:1902761 ! positive regulation of chondrocyte development
-is_a: GO:0010720 {is_inferred="true"} ! positive regulation of cell development
-is_a: GO:0032332 {is_inferred="true"} ! positive regulation of chondrocyte differentiation
-is_a: GO:0061181 {is_inferred="true"} ! regulation of chondrocyte development
-
-[Term]
 id: GO:1902762 ! regulation of embryonic skeletal joint development
 is_a: GO:0045995 {is_inferred="true"} ! regulation of embryonic development
 
@@ -79051,22 +75592,6 @@
 is_a: GO:0043241 {is_inferred="true"} ! protein complex disassembly
 
 [Term]
-id: GO:1903010 ! regulation of bone development
-is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
-
-[Term]
-id: GO:1903011 ! negative regulation of bone development
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-is_a: GO:1903010 {is_inferred="true"} ! regulation of bone development
-
-[Term]
-id: GO:1903012 ! positive regulation of bone development
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-is_a: GO:1903010 {is_inferred="true"} ! regulation of bone development
-
-[Term]
 id: GO:1903013 ! response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one
 is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
 is_a: GO:0045472 {is_inferred="true"} ! response to ether
@@ -79167,58 +75692,10 @@
 is_a: GO:1904528 {is_inferred="true"} ! positive regulation of microtubule binding
 
 [Term]
-id: GO:1903034 ! regulation of response to wounding
-is_a: GO:0080134 {is_inferred="true"} ! regulation of response to stress
-
-[Term]
-id: GO:1903035 ! negative regulation of response to wounding
-is_a: GO:0048585 {is_inferred="true"} ! negative regulation of response to stimulus
-is_a: GO:1903034 {is_inferred="true"} ! regulation of response to wounding
-
-[Term]
-id: GO:1903036 ! positive regulation of response to wounding
-is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
-is_a: GO:1903034 {is_inferred="true"} ! regulation of response to wounding
-
-[Term]
-id: GO:1903037 ! regulation of leukocyte cell-cell adhesion
-is_a: GO:0022407 {is_inferred="true"} ! regulation of cell-cell adhesion
-
-[Term]
-id: GO:1903038 ! negative regulation of leukocyte cell-cell adhesion
-is_a: GO:0022408 {is_inferred="true"} ! negative regulation of cell-cell adhesion
-is_a: GO:1903037 {is_inferred="true"} ! regulation of leukocyte cell-cell adhesion
-
-[Term]
-id: GO:1903039 ! positive regulation of leukocyte cell-cell adhesion
-is_a: GO:0022409 {is_inferred="true"} ! positive regulation of cell-cell adhesion
-is_a: GO:1903037 {is_inferred="true"} ! regulation of leukocyte cell-cell adhesion
-
-[Term]
 id: GO:1903040 ! exon-exon junction complex assembly
 is_a: GO:0006461 {is_inferred="true"} ! protein complex assembly
 
 [Term]
-id: GO:1903041 ! regulation of chondrocyte hypertrophy
-is_a: GO:0001558 {is_inferred="true"} ! regulation of cell growth
-is_a: GO:0048638 {is_inferred="true"} ! regulation of developmental growth
-is_a: GO:0061181 {is_inferred="true"} ! regulation of chondrocyte development
-
-[Term]
-id: GO:1903042 ! negative regulation of chondrocyte hypertrophy
-is_a: GO:0030308 {is_inferred="true"} ! negative regulation of cell growth
-is_a: GO:0048640 {is_inferred="true"} ! negative regulation of developmental growth
-is_a: GO:0061182 {is_inferred="true"} ! negative regulation of chondrocyte development
-is_a: GO:1903041 {is_inferred="true"} ! regulation of chondrocyte hypertrophy
-
-[Term]
-id: GO:1903043 ! positive regulation of chondrocyte hypertrophy
-is_a: GO:0030307 {is_inferred="true"} ! positive regulation of cell growth
-is_a: GO:0048639 {is_inferred="true"} ! positive regulation of developmental growth
-is_a: GO:1902761 {is_inferred="true"} ! positive regulation of chondrocyte development
-is_a: GO:1903041 {is_inferred="true"} ! regulation of chondrocyte hypertrophy
-
-[Term]
 id: GO:1903044 ! protein localization to membrane raft
 is_a: GO:0072657 {is_inferred="true"} ! protein localization to membrane
 
@@ -79227,11 +75704,6 @@
 is_a: GO:1901166 {is_inferred="true"} ! neural crest cell migration involved in autonomic nervous system development
 
 [Term]
-id: GO:1903046 ! meiotic cell cycle process
-is_a: GO:0022402 {is_inferred="true"} ! cell cycle process
-is_a: GO:0022414 {is_inferred="true"} ! reproductive process
-
-[Term]
 id: GO:1903047 ! mitotic cell cycle process
 is_a: GO:0022402 {is_inferred="true"} ! cell cycle process
 
@@ -79265,20 +75737,6 @@
 is_a: GO:1903364 {is_inferred="true"} ! positive regulation of cellular protein catabolic process
 
 [Term]
-id: GO:1903053 ! regulation of extracellular matrix organization
-is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
-
-[Term]
-id: GO:1903054 ! negative regulation of extracellular matrix organization
-is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
-is_a: GO:1903053 {is_inferred="true"} ! regulation of extracellular matrix organization
-
-[Term]
-id: GO:1903055 ! positive regulation of extracellular matrix organization
-is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
-is_a: GO:1903053 {is_inferred="true"} ! regulation of extracellular matrix organization
-
-[Term]
 id: GO:1903056 ! regulation of melanosome organization
 is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
 
@@ -81043,20 +77501,6 @@
 is_a: GO:2000379 {is_inferred="true"} ! positive regulation of reactive oxygen species metabolic process
 
 [Term]
-id: GO:1903429 ! regulation of cell maturation
-is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
-
-[Term]
-id: GO:1903430 ! negative regulation of cell maturation
-is_a: GO:0010721 {is_inferred="true"} ! negative regulation of cell development
-is_a: GO:1903429 {is_inferred="true"} ! regulation of cell maturation
-
-[Term]
-id: GO:1903431 ! positive regulation of cell maturation
-is_a: GO:0010720 {is_inferred="true"} ! positive regulation of cell development
-is_a: GO:1903429 {is_inferred="true"} ! regulation of cell maturation
-
-[Term]
 id: GO:1903432 ! regulation of TORC1 signaling
 is_a: GO:0032006 {is_inferred="true"} ! regulation of TOR signaling
 
@@ -81322,26 +77766,6 @@
 is_a: GO:1902405 {is_inferred="true"} ! mitotic actomyosin contractile ring localization
 
 [Term]
-id: GO:1903487 ! regulation of lactation
-is_a: GO:0050878 {is_inferred="true"} ! regulation of body fluid levels
-is_a: GO:0051046 {is_inferred="true"} ! regulation of secretion
-is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
-
-[Term]
-id: GO:1903488 ! negative regulation of lactation
-is_a: GO:0051048 {is_inferred="true"} ! negative regulation of secretion
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-is_a: GO:1903487 {is_inferred="true"} ! regulation of lactation
-
-[Term]
-id: GO:1903489 ! positive regulation of lactation
-is_a: GO:0051047 {is_inferred="true"} ! positive regulation of secretion
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-is_a: GO:1903487 {is_inferred="true"} ! regulation of lactation
-
-[Term]
 id: GO:1903490 ! positive regulation of mitotic cytokinesis
 is_a: GO:0032467 {is_inferred="true"} ! positive regulation of cytokinesis
 is_a: GO:0045931 {is_inferred="true"} ! positive regulation of mitotic cell cycle
@@ -81502,20 +77926,6 @@
 is_a: GO:1903519 {is_inferred="true"} ! regulation of mammary gland involution
 
 [Term]
-id: GO:1903522 ! regulation of blood circulation
-is_a: GO:0044057 {is_inferred="true"} ! regulation of system process
-
-[Term]
-id: GO:1903523 ! negative regulation of blood circulation
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-is_a: GO:1903522 {is_inferred="true"} ! regulation of blood circulation
-
-[Term]
-id: GO:1903524 ! positive regulation of blood circulation
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-is_a: GO:1903522 {is_inferred="true"} ! regulation of blood circulation
-
-[Term]
 id: GO:1903525 ! regulation of membrane tubulation
 is_a: GO:1903729 {is_inferred="true"} ! regulation of plasma membrane organization
 
@@ -81539,23 +77949,6 @@
 is_a: GO:1903528 {is_inferred="true"} ! regulation of dCDP biosynthetic process
 
 [Term]
-id: GO:1903530 ! regulation of secretion by cell
-is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
-is_a: GO:0051046 {is_inferred="true"} ! regulation of secretion
-
-[Term]
-id: GO:1903531 ! negative regulation of secretion by cell
-is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
-is_a: GO:0051048 {is_inferred="true"} ! negative regulation of secretion
-is_a: GO:1903530 {is_inferred="true"} ! regulation of secretion by cell
-
-[Term]
-id: GO:1903532 ! positive regulation of secretion by cell
-is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
-is_a: GO:0051047 {is_inferred="true"} ! positive regulation of secretion
-is_a: GO:1903530 {is_inferred="true"} ! regulation of secretion by cell
-
-[Term]
 id: GO:1903533 ! regulation of protein targeting
 is_a: GO:0033157 {is_inferred="true"} ! regulation of intracellular protein transport
 
@@ -81690,11 +78083,6 @@
 is_a: GO:1903558 {is_inferred="true"} ! 3-cyano-L-alanine metabolic process
 
 [Term]
-id: GO:1903561 ! extracellular vesicle
-is_a: GO:0031982 {is_inferred="true"} ! vesicle
-is_a: GO:0043230 {is_inferred="true"} ! extracellular organelle
-
-[Term]
 id: GO:1903562 ! microtubule bundle formation involved in mitotic spindle midzone assembly
 is_a: GO:0001578 {is_inferred="true"} ! microtubule bundle formation
 is_a: GO:1902850 {is_inferred="true"} ! microtubule cytoskeleton organization involved in mitosis
@@ -82446,25 +78834,6 @@
 is_a: GO:1900370 {is_inferred="true"} ! positive regulation of RNA interference
 
 [Term]
-id: GO:1903706 ! regulation of hemopoiesis
-is_a: GO:0002682 {is_inferred="true"} ! regulation of immune system process
-is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
-
-[Term]
-id: GO:1903707 ! negative regulation of hemopoiesis
-is_a: GO:0002683 {is_inferred="true"} ! negative regulation of immune system process
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-is_a: GO:1903706 {is_inferred="true"} ! regulation of hemopoiesis
-
-[Term]
-id: GO:1903708 ! positive regulation of hemopoiesis
-is_a: GO:0002684 {is_inferred="true"} ! positive regulation of immune system process
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-is_a: GO:1903706 {is_inferred="true"} ! regulation of hemopoiesis
-
-[Term]
 id: GO:1903709 ! uterine gland development
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:0048608 {is_inferred="true"} ! reproductive structure development
@@ -82855,16 +79224,6 @@
 is_a: GO:1904082 {is_inferred="true"} ! pyrimidine nucleobase transmembrane transport
 
 [Term]
-id: GO:1903792 ! negative regulation of anion transport
-is_a: GO:0043271 {is_inferred="true"} ! negative regulation of ion transport
-is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
-
-[Term]
-id: GO:1903793 ! positive regulation of anion transport
-is_a: GO:0043270 {is_inferred="true"} ! positive regulation of ion transport
-is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
-
-[Term]
 id: GO:1903794 ! cortisol binding
 is_a: GO:1990239 {is_inferred="true"} ! steroid hormone binding
 
@@ -83564,16 +79923,6 @@
 is_a: GO:1903939 {is_inferred="true"} ! regulation of TORC2 signaling
 
 [Term]
-id: GO:1903941 ! negative regulation of respiratory gaseous exchange
-is_a: GO:0043576 {is_inferred="true"} ! regulation of respiratory gaseous exchange
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-
-[Term]
-id: GO:1903942 ! positive regulation of respiratory gaseous exchange
-is_a: GO:0043576 {is_inferred="true"} ! regulation of respiratory gaseous exchange
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-
-[Term]
 id: GO:1903943 ! regulation of hepatocyte apoptotic process
 is_a: GO:1904035 {is_inferred="true"} ! regulation of epithelial cell apoptotic process
 
@@ -83938,12 +80287,6 @@
 is_a: GO:1904016 {is_inferred="true"} ! response to Thyroglobulin triiodothyronine
 
 [Term]
-id: GO:1904018 ! positive regulation of vasculature development
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-is_a: GO:1901342 {is_inferred="true"} ! regulation of vasculature development
-
-[Term]
 id: GO:1904020 ! regulation of G-protein coupled receptor internalization
 is_a: GO:0002090 {is_inferred="true"} ! regulation of receptor internalization
 is_a: GO:0008277 {is_inferred="true"} ! regulation of G-protein coupled receptor protein signaling pathway
@@ -84138,16 +80481,6 @@
 is_a: GO:1904054 {is_inferred="true"} ! regulation of cholangiocyte proliferation
 
 [Term]
-id: GO:1904057 ! negative regulation of sensory perception of pain
-is_a: GO:0031645 {is_inferred="true"} ! negative regulation of neurological system process
-is_a: GO:0051930 {is_inferred="true"} ! regulation of sensory perception of pain
-
-[Term]
-id: GO:1904058 ! positive regulation of sensory perception of pain
-is_a: GO:0031646 {is_inferred="true"} ! positive regulation of neurological system process
-is_a: GO:0051930 {is_inferred="true"} ! regulation of sensory perception of pain
-
-[Term]
 id: GO:1904059 ! regulation of locomotor rhythm
 is_a: GO:0042752 {is_inferred="true"} ! regulation of circadian rhythm
 is_a: GO:0050795 {is_inferred="true"} ! regulation of behavior
@@ -84408,11 +80741,6 @@
 is_a: GO:1903116 {is_inferred="true"} ! positive regulation of actin filament-based movement
 
 [Term]
-id: GO:1904115 ! axon cytoplasm
-is_a: GO:0032838 {is_inferred="true"} ! cell projection cytoplasm
-is_a: GO:0033267 {is_inferred="true"} ! axon part
-
-[Term]
 id: GO:1904116 ! response to vasopressin
 is_a: GO:0043434 {is_inferred="true"} ! response to peptide hormone
 
@@ -85069,23 +81397,6 @@
 is_a: GO:1904248 {is_inferred="true"} ! regulation of age-related resistance
 
 [Term]
-id: GO:1904251 ! regulation of bile acid metabolic process
-is_a: GO:0019218 {is_inferred="true"} ! regulation of steroid metabolic process
-is_a: GO:0031323 {is_inferred="true"} ! regulation of cellular metabolic process
-
-[Term]
-id: GO:1904252 ! negative regulation of bile acid metabolic process
-is_a: GO:0031324 {is_inferred="true"} ! negative regulation of cellular metabolic process
-is_a: GO:0045939 {is_inferred="true"} ! negative regulation of steroid metabolic process
-is_a: GO:1904251 {is_inferred="true"} ! regulation of bile acid metabolic process
-
-[Term]
-id: GO:1904253 ! positive regulation of bile acid metabolic process
-is_a: GO:0031325 {is_inferred="true"} ! positive regulation of cellular metabolic process
-is_a: GO:0045940 {is_inferred="true"} ! positive regulation of steroid metabolic process
-is_a: GO:1904251 {is_inferred="true"} ! regulation of bile acid metabolic process
-
-[Term]
 id: GO:1904254 ! regulation of iron channel activity
 is_a: GO:0034759 {is_inferred="true"} ! regulation of iron ion transmembrane transport
 is_a: GO:2001257 {is_inferred="true"} ! regulation of cation channel activity
@@ -85423,22 +81734,6 @@
 is_a: GO:1904316 {is_inferred="true"} ! response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine
 
 [Term]
-id: GO:1904318 ! regulation of smooth muscle contraction involved in micturition
-is_a: GO:0006940 {is_inferred="true"} ! regulation of smooth muscle contraction
-is_a: GO:0044062 {is_inferred="true"} ! regulation of excretion
-is_a: GO:0098801 {is_inferred="true"} ! regulation of renal system process
-
-[Term]
-id: GO:1904319 ! negative regulation of smooth muscle contraction involved in micturition
-is_a: GO:0045986 {is_inferred="true"} ! negative regulation of smooth muscle contraction
-is_a: GO:1904318 {is_inferred="true"} ! regulation of smooth muscle contraction involved in micturition
-
-[Term]
-id: GO:1904320 ! positive regulation of smooth muscle contraction involved in micturition
-is_a: GO:0045987 {is_inferred="true"} ! positive regulation of smooth muscle contraction
-is_a: GO:1904318 {is_inferred="true"} ! regulation of smooth muscle contraction involved in micturition
-
-[Term]
 id: GO:1904321 ! response to forskolin
 is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
 is_a: GO:0033993 {is_inferred="true"} ! response to lipid
@@ -85640,20 +81935,6 @@
 is_a: GO:1904359 {is_inferred="true"} ! regulation of spore germination
 
 [Term]
-id: GO:1904362 ! regulation of calcitonin secretion
-is_a: GO:0090276 {is_inferred="true"} ! regulation of peptide hormone secretion
-
-[Term]
-id: GO:1904363 ! negative regulation of calcitonin secretion
-is_a: GO:0090278 {is_inferred="true"} ! negative regulation of peptide hormone secretion
-is_a: GO:1904362 {is_inferred="true"} ! regulation of calcitonin secretion
-
-[Term]
-id: GO:1904364 ! positive regulation of calcitonin secretion
-is_a: GO:0090277 {is_inferred="true"} ! positive regulation of peptide hormone secretion
-is_a: GO:1904362 {is_inferred="true"} ! regulation of calcitonin secretion
-
-[Term]
 id: GO:1904365 ! regulation of chemokinesis
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
 
@@ -88515,16 +84796,6 @@
 is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
 
 [Term]
-id: GO:1904950 ! negative regulation of establishment of protein localization
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
-is_a: GO:0070201 {is_inferred="true"} ! regulation of establishment of protein localization
-
-[Term]
-id: GO:1904951 ! positive regulation of establishment of protein localization
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
-is_a: GO:0070201 {is_inferred="true"} ! regulation of establishment of protein localization
-
-[Term]
 id: GO:1904952 ! hydroxycinnamic acid transport
 is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
 
@@ -90117,23 +86388,6 @@
 is_a: GO:0030182 {is_inferred="true"} ! neuron differentiation
 
 [Term]
-id: GO:1905276 ! regulation of epithelial tube formation
-is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
-is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
-
-[Term]
-id: GO:1905277 ! negative regulation of epithelial tube formation
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-is_a: GO:1905276 {is_inferred="true"} ! regulation of epithelial tube formation
-is_a: GO:1905331 {is_inferred="true"} ! negative regulation of morphogenesis of an epithelium
-
-[Term]
-id: GO:1905278 ! positive regulation of epithelial tube formation
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-is_a: GO:1905276 {is_inferred="true"} ! regulation of epithelial tube formation
-is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
-
-[Term]
 id: GO:1905279 ! regulation of retrograde transport, endosome to Golgi
 is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
 is_a: GO:1903649 {is_inferred="true"} ! regulation of cytoplasmic transport
@@ -90408,20 +86662,6 @@
 is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 
 [Term]
-id: GO:1905330 ! regulation of morphogenesis of an epithelium
-is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
-
-[Term]
-id: GO:1905331 ! negative regulation of morphogenesis of an epithelium
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
-is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
-
-[Term]
-id: GO:1905332 ! positive regulation of morphogenesis of an epithelium
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
-is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
-
-[Term]
 id: GO:1905333 ! regulation of gastric motility
 is_a: GO:0044058 {is_inferred="true"} ! regulation of digestive system process
 
@@ -91473,24 +87713,6 @@
 is_a: GO:1905550 {is_inferred="true"} ! regulation of protein localization to endoplasmic reticulum
 
 [Term]
-id: GO:1905553 ! regulation of blood vessel branching
-is_a: GO:0045765 {is_inferred="true"} ! regulation of angiogenesis
-is_a: GO:0060688 {is_inferred="true"} ! regulation of morphogenesis of a branching structure
-is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
-
-[Term]
-id: GO:1905554 ! negative regulation of vessel branching
-is_a: GO:0016525 {is_inferred="true"} ! negative regulation of angiogenesis
-is_a: GO:1905331 {is_inferred="true"} ! negative regulation of morphogenesis of an epithelium
-is_a: GO:1905553 {is_inferred="true"} ! regulation of blood vessel branching
-
-[Term]
-id: GO:1905555 ! positive regulation blood vessel branching
-is_a: GO:0045766 {is_inferred="true"} ! positive regulation of angiogenesis
-is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
-is_a: GO:1905553 {is_inferred="true"} ! regulation of blood vessel branching
-
-[Term]
 id: GO:1905556 ! ciliary vesicle assembly
 is_a: GO:0016050 {is_inferred="true"} ! vesicle organization
 is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
@@ -93453,10 +89675,6 @@
 is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
 
 [Term]
-id: GO:2000021 ! regulation of ion homeostasis
-is_a: GO:0032844 {is_inferred="true"} ! regulation of homeostatic process
-
-[Term]
 id: GO:2000022 ! regulation of jasmonic acid mediated signaling pathway
 is_a: GO:0009966 {is_inferred="true"} ! regulation of signal transduction
 
@@ -93474,15 +89692,6 @@
 is_a: GO:1905428 {is_inferred="true"} ! regulation of plant organ formation
 
 [Term]
-id: GO:2000026 ! regulation of multicellular organismal development
-is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
-
-[Term]
-id: GO:2000027 ! regulation of organ morphogenesis
-is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
-is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
-
-[Term]
 id: GO:2000028 ! regulation of photoperiodism, flowering
 is_a: GO:0048580 {is_inferred="true"} ! regulation of post-embryonic development
 is_a: GO:0048583 {is_inferred="true"} ! regulation of response to stimulus
@@ -93517,10 +89726,6 @@
 is_a: GO:0080050 {is_inferred="true"} ! regulation of seed development
 
 [Term]
-id: GO:2000035 ! regulation of stem cell division
-is_a: GO:0051302 {is_inferred="true"} ! regulation of cell division
-
-[Term]
 id: GO:2000036 ! regulation of stem cell population maintenance
 is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
 is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
@@ -93695,10 +89900,6 @@
 is_a: GO:2000280 {is_inferred="true"} ! regulation of root development
 
 [Term]
-id: GO:2000070 ! regulation of response to water deprivation
-is_a: GO:0080134 {is_inferred="true"} ! regulation of response to stress
-
-[Term]
 id: GO:2000071 ! regulation of defense response by callose deposition
 is_a: GO:0031347 {is_inferred="true"} ! regulation of defense response
 is_a: GO:0032879 {is_inferred="true"} ! regulation of localization
@@ -93924,17 +90125,6 @@
 is_a: GO:2000109 {is_inferred="true"} ! regulation of macrophage apoptotic process
 
 [Term]
-id: GO:2000112 ! regulation of cellular macromolecule biosynthetic process
-is_a: GO:0010556 {is_inferred="true"} ! regulation of macromolecule biosynthetic process
-is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
-
-[Term]
-id: GO:2000113 ! negative regulation of cellular macromolecule biosynthetic process
-is_a: GO:0010558 {is_inferred="true"} ! negative regulation of macromolecule biosynthetic process
-is_a: GO:0031327 {is_inferred="true"} ! negative regulation of cellular biosynthetic process
-is_a: GO:2000112 {is_inferred="true"} ! regulation of cellular macromolecule biosynthetic process
-
-[Term]
 id: GO:2000114 ! regulation of establishment of cell polarity
 is_a: GO:0032878 {is_inferred="true"} ! regulation of establishment or maintenance of cell polarity
 
@@ -94080,23 +90270,6 @@
 is_a: GO:2000142 {is_inferred="true"} ! regulation of DNA-templated transcription, initiation
 
 [Term]
-id: GO:2000145 ! regulation of cell motility
-is_a: GO:0040012 {is_inferred="true"} ! regulation of locomotion
-is_a: GO:0051270 {is_inferred="true"} ! regulation of cellular component movement
-
-[Term]
-id: GO:2000146 ! negative regulation of cell motility
-is_a: GO:0040013 {is_inferred="true"} ! negative regulation of locomotion
-is_a: GO:0051271 {is_inferred="true"} ! negative regulation of cellular component movement
-is_a: GO:2000145 {is_inferred="true"} ! regulation of cell motility
-
-[Term]
-id: GO:2000147 ! positive regulation of cell motility
-is_a: GO:0040017 {is_inferred="true"} ! positive regulation of locomotion
-is_a: GO:0051272 {is_inferred="true"} ! positive regulation of cellular component movement
-is_a: GO:2000145 {is_inferred="true"} ! regulation of cell motility
-
-[Term]
 id: GO:2000148 ! regulation of planar cell polarity pathway involved in ventricular septum morphogenesis
 is_a: GO:1901219 {is_inferred="true"} ! regulation of cardiac chamber morphogenesis
 is_a: GO:1904412 {is_inferred="true"} ! regulation of cardiac ventricle development
@@ -94260,11 +90433,6 @@
 is_a: GO:0032353 {is_inferred="true"} ! negative regulation of hormone biosynthetic process
 
 [Term]
-id: GO:2000181 ! negative regulation of blood vessel morphogenesis
-is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
-is_a: GO:1901343 {is_inferred="true"} ! negative regulation of vasculature development
-
-[Term]
 id: GO:2000182 ! regulation of progesterone biosynthetic process
 is_a: GO:0010566 {is_inferred="true"} ! regulation of ketone biosynthetic process
 is_a: GO:0046885 {is_inferred="true"} ! regulation of hormone biosynthetic process
@@ -94327,25 +90495,6 @@
 is_a: GO:2000191 {is_inferred="true"} ! regulation of fatty acid transport
 
 [Term]
-id: GO:2000194 ! regulation of female gonad development
-is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
-is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
-
-[Term]
-id: GO:2000195 ! negative regulation of female gonad development
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-is_a: GO:2000194 {is_inferred="true"} ! regulation of female gonad development
-is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
-
-[Term]
-id: GO:2000196 ! positive regulation of female gonad development
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-is_a: GO:2000194 {is_inferred="true"} ! regulation of female gonad development
-is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
-
-[Term]
 id: GO:2000197 ! regulation of ribonucleoprotein complex localization
 is_a: GO:0060341 {is_inferred="true"} ! regulation of cellular localization
 
@@ -94417,20 +90566,6 @@
 is_a: GO:2000209 {is_inferred="true"} ! regulation of anoikis
 
 [Term]
-id: GO:2000211 ! regulation of glutamate metabolic process
-is_a: GO:0000820 {is_inferred="true"} ! regulation of glutamine family amino acid metabolic process
-
-[Term]
-id: GO:2000212 ! negative regulation of glutamate metabolic process
-is_a: GO:0045763 {is_inferred="true"} ! negative regulation of cellular amino acid metabolic process
-is_a: GO:2000211 {is_inferred="true"} ! regulation of glutamate metabolic process
-
-[Term]
-id: GO:2000213 ! positive regulation of glutamate metabolic process
-is_a: GO:0045764 {is_inferred="true"} ! positive regulation of cellular amino acid metabolic process
-is_a: GO:2000211 {is_inferred="true"} ! regulation of glutamate metabolic process
-
-[Term]
 id: GO:2000214 ! regulation of proline metabolic process
 is_a: GO:0000820 {is_inferred="true"} ! regulation of glutamine family amino acid metabolic process
 
@@ -94578,20 +90713,6 @@
 is_a: GO:2000238 {is_inferred="true"} ! regulation of tRNA export from nucleus
 
 [Term]
-id: GO:2000241 ! regulation of reproductive process
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-
-[Term]
-id: GO:2000242 ! negative regulation of reproductive process
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
-is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
-
-[Term]
-id: GO:2000243 ! positive regulation of reproductive process
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
-is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
-
-[Term]
 id: GO:2000244 ! regulation of FtsZ-dependent cytokinesis
 is_a: GO:0032465 {is_inferred="true"} ! regulation of cytokinesis
 is_a: GO:1903664 {is_inferred="true"} ! regulation of asexual reproduction
@@ -94639,16 +90760,6 @@
 is_a: GO:2000249 {is_inferred="true"} ! regulation of actin cytoskeleton reorganization
 
 [Term]
-id: GO:2000252 ! negative regulation of feeding behavior
-is_a: GO:0048521 {is_inferred="true"} ! negative regulation of behavior
-is_a: GO:0060259 {is_inferred="true"} ! regulation of feeding behavior
-
-[Term]
-id: GO:2000253 ! positive regulation of feeding behavior
-is_a: GO:0048520 {is_inferred="true"} ! positive regulation of behavior
-is_a: GO:0060259 {is_inferred="true"} ! regulation of feeding behavior
-
-[Term]
 id: GO:2000254 ! regulation of male germ cell proliferation
 is_a: GO:0042127 {is_inferred="true"} ! regulation of cell proliferation
 is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
@@ -94752,16 +90863,6 @@
 is_a: GO:2000269 {is_inferred="true"} ! regulation of fibroblast apoptotic process
 
 [Term]
-id: GO:2000272 ! negative regulation of receptor activity
-is_a: GO:0010469 {is_inferred="true"} ! regulation of receptor activity
-is_a: GO:0044092 {is_inferred="true"} ! negative regulation of molecular function
-
-[Term]
-id: GO:2000273 ! positive regulation of receptor activity
-is_a: GO:0010469 {is_inferred="true"} ! regulation of receptor activity
-is_a: GO:0044093 {is_inferred="true"} ! positive regulation of molecular function
-
-[Term]
 id: GO:2000274 ! regulation of epithelial cell migration, open tracheal system
 is_a: GO:0010632 {is_inferred="true"} ! regulation of epithelial cell migration
 is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
@@ -94849,20 +90950,6 @@
 is_a: GO:0042127 {is_inferred="true"} ! regulation of cell proliferation
 
 [Term]
-id: GO:2000292 ! regulation of defecation
-is_a: GO:0044062 {is_inferred="true"} ! regulation of excretion
-
-[Term]
-id: GO:2000293 ! negative regulation of defecation
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-is_a: GO:2000292 {is_inferred="true"} ! regulation of defecation
-
-[Term]
-id: GO:2000294 ! positive regulation of defecation
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-is_a: GO:2000292 {is_inferred="true"} ! regulation of defecation
-
-[Term]
 id: GO:2000295 ! regulation of hydrogen peroxide catabolic process
 is_a: GO:0010310 {is_inferred="true"} ! regulation of hydrogen peroxide metabolic process
 is_a: GO:0031329 {is_inferred="true"} ! regulation of cellular catabolic process
@@ -95310,34 +91397,6 @@
 is_a: GO:2000377 {is_inferred="true"} ! regulation of reactive oxygen species metabolic process
 
 [Term]
-id: GO:2000380 ! regulation of mesoderm development
-is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
-
-[Term]
-id: GO:2000381 ! negative regulation of mesoderm development
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
-is_a: GO:2000380 {is_inferred="true"} ! regulation of mesoderm development
-
-[Term]
-id: GO:2000382 ! positive regulation of mesoderm development
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
-is_a: GO:2000380 {is_inferred="true"} ! regulation of mesoderm development
-
-[Term]
-id: GO:2000383 ! regulation of ectoderm development
-is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
-
-[Term]
-id: GO:2000384 ! negative regulation of ectoderm development
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
-is_a: GO:2000383 {is_inferred="true"} ! regulation of ectoderm development
-
-[Term]
-id: GO:2000385 ! positive regulation of ectoderm development
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
-is_a: GO:2000383 {is_inferred="true"} ! regulation of ectoderm development
-
-[Term]
 id: GO:2000386 ! positive regulation of ovarian follicle development
 is_a: GO:2000196 {is_inferred="true"} ! positive regulation of female gonad development
 is_a: GO:2000354 {is_inferred="true"} ! regulation of ovarian follicle development
@@ -96092,16 +92151,6 @@
 is_a: GO:2000539 {is_inferred="true"} ! regulation of protein geranylgeranylation
 
 [Term]
-id: GO:2000542 ! negative regulation of gastrulation
-is_a: GO:0010470 {is_inferred="true"} ! regulation of gastrulation
-is_a: GO:0045992 {is_inferred="true"} ! negative regulation of embryonic development
-
-[Term]
-id: GO:2000543 ! positive regulation of gastrulation
-is_a: GO:0010470 {is_inferred="true"} ! regulation of gastrulation
-is_a: GO:0040019 {is_inferred="true"} ! positive regulation of embryonic development
-
-[Term]
 id: GO:2000544 ! regulation of endothelial cell chemotaxis to fibroblast growth factor
 is_a: GO:1904847 {is_inferred="true"} ! regulation of cell chemotaxis to fibroblast growth factor
 is_a: GO:2001026 {is_inferred="true"} ! regulation of endothelial cell chemotaxis
@@ -96422,26 +92471,6 @@
 is_a: GO:2000606 {is_inferred="true"} ! regulation of cell proliferation involved in mesonephros development
 
 [Term]
-id: GO:2000609 ! regulation of thyroid hormone generation
-is_a: GO:0031323 {is_inferred="true"} ! regulation of cellular metabolic process
-is_a: GO:0032350 {is_inferred="true"} ! regulation of hormone metabolic process
-is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
-
-[Term]
-id: GO:2000610 ! negative regulation of thyroid hormone generation
-is_a: GO:0031324 {is_inferred="true"} ! negative regulation of cellular metabolic process
-is_a: GO:0032351 {is_inferred="true"} ! negative regulation of hormone metabolic process
-is_a: GO:0051172 {is_inferred="true"} ! negative regulation of nitrogen compound metabolic process
-is_a: GO:2000609 {is_inferred="true"} ! regulation of thyroid hormone generation
-
-[Term]
-id: GO:2000611 ! positive regulation of thyroid hormone generation
-is_a: GO:0031325 {is_inferred="true"} ! positive regulation of cellular metabolic process
-is_a: GO:0032352 {is_inferred="true"} ! positive regulation of hormone metabolic process
-is_a: GO:0051173 {is_inferred="true"} ! positive regulation of nitrogen compound metabolic process
-is_a: GO:2000609 {is_inferred="true"} ! regulation of thyroid hormone generation
-
-[Term]
 id: GO:2000612 ! regulation of thyroid-stimulating hormone secretion
 is_a: GO:0090276 {is_inferred="true"} ! regulation of peptide hormone secretion
 
@@ -97502,10 +93531,6 @@
 is_a: GO:0000122 {is_inferred="true"} ! negative regulation of transcription from RNA polymerase II promoter
 
 [Term]
-id: GO:2000821 ! regulation of grooming behavior
-is_a: GO:0050795 {is_inferred="true"} ! regulation of behavior
-
-[Term]
 id: GO:2000822 ! regulation of behavioral fear response
 is_a: GO:0031347 {is_inferred="true"} ! regulation of defense response
 is_a: GO:0050795 {is_inferred="true"} ! regulation of behavior
@@ -97542,43 +93567,6 @@
 is_a: GO:0071026 {is_inferred="true"} ! cytoplasmic RNA surveillance
 
 [Term]
-id: GO:2000828 ! regulation of parathyroid hormone secretion
-is_a: GO:0044060 {is_inferred="true"} ! regulation of endocrine process
-is_a: GO:0046883 {is_inferred="true"} ! regulation of hormone secretion
-
-[Term]
-id: GO:2000829 ! negative regulation of parathyroid hormone secretion
-is_a: GO:0046888 {is_inferred="true"} ! negative regulation of hormone secretion
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-is_a: GO:2000828 {is_inferred="true"} ! regulation of parathyroid hormone secretion
-
-[Term]
-id: GO:2000830 ! positive regulation of parathyroid hormone secretion
-is_a: GO:0046887 {is_inferred="true"} ! positive regulation of hormone secretion
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-is_a: GO:2000828 {is_inferred="true"} ! regulation of parathyroid hormone secretion
-
-[Term]
-id: GO:2000831 ! regulation of steroid hormone secretion
-is_a: GO:0032368 {is_inferred="true"} ! regulation of lipid transport
-is_a: GO:0044060 {is_inferred="true"} ! regulation of endocrine process
-is_a: GO:0046883 {is_inferred="true"} ! regulation of hormone secretion
-
-[Term]
-id: GO:2000832 ! negative regulation of steroid hormone secretion
-is_a: GO:0032369 {is_inferred="true"} ! negative regulation of lipid transport
-is_a: GO:0046888 {is_inferred="true"} ! negative regulation of hormone secretion
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-is_a: GO:2000831 {is_inferred="true"} ! regulation of steroid hormone secretion
-
-[Term]
-id: GO:2000833 ! positive regulation of steroid hormone secretion
-is_a: GO:0032370 {is_inferred="true"} ! positive regulation of lipid transport
-is_a: GO:0046887 {is_inferred="true"} ! positive regulation of hormone secretion
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-is_a: GO:2000831 {is_inferred="true"} ! regulation of steroid hormone secretion
-
-[Term]
 id: GO:2000834 ! regulation of androgen secretion
 is_a: GO:2000831 {is_inferred="true"} ! regulation of steroid hormone secretion
 
@@ -97644,20 +93632,6 @@
 is_a: GO:2000843 {is_inferred="true"} ! regulation of testosterone secretion
 
 [Term]
-id: GO:2000846 ! regulation of corticosteroid hormone secretion
-is_a: GO:2000831 {is_inferred="true"} ! regulation of steroid hormone secretion
-
-[Term]
-id: GO:2000847 ! negative regulation of corticosteroid hormone secretion
-is_a: GO:2000832 {is_inferred="true"} ! negative regulation of steroid hormone secretion
-is_a: GO:2000846 {is_inferred="true"} ! regulation of corticosteroid hormone secretion
-
-[Term]
-id: GO:2000848 ! positive regulation of corticosteroid hormone secretion
-is_a: GO:2000833 {is_inferred="true"} ! positive regulation of steroid hormone secretion
-is_a: GO:2000846 {is_inferred="true"} ! regulation of corticosteroid hormone secretion
-
-[Term]
 id: GO:2000849 ! regulation of glucocorticoid secretion
 is_a: GO:2000846 {is_inferred="true"} ! regulation of corticosteroid hormone secretion
 
@@ -97686,34 +93660,6 @@
 is_a: GO:2000852 {is_inferred="true"} ! regulation of corticosterone secretion
 
 [Term]
-id: GO:2000855 ! regulation of mineralocorticoid secretion
-is_a: GO:2000846 {is_inferred="true"} ! regulation of corticosteroid hormone secretion
-
-[Term]
-id: GO:2000856 ! negative regulation of mineralocorticoid secretion
-is_a: GO:2000847 {is_inferred="true"} ! negative regulation of corticosteroid hormone secretion
-is_a: GO:2000855 {is_inferred="true"} ! regulation of mineralocorticoid secretion
-
-[Term]
-id: GO:2000857 ! positive regulation of mineralocorticoid secretion
-is_a: GO:2000848 {is_inferred="true"} ! positive regulation of corticosteroid hormone secretion
-is_a: GO:2000855 {is_inferred="true"} ! regulation of mineralocorticoid secretion
-
-[Term]
-id: GO:2000858 ! regulation of aldosterone secretion
-is_a: GO:2000855 {is_inferred="true"} ! regulation of mineralocorticoid secretion
-
-[Term]
-id: GO:2000859 ! negative regulation of aldosterone secretion
-is_a: GO:2000856 {is_inferred="true"} ! negative regulation of mineralocorticoid secretion
-is_a: GO:2000858 {is_inferred="true"} ! regulation of aldosterone secretion
-
-[Term]
-id: GO:2000860 ! positive regulation of aldosterone secretion
-is_a: GO:2000857 {is_inferred="true"} ! positive regulation of mineralocorticoid secretion
-is_a: GO:2000858 {is_inferred="true"} ! regulation of aldosterone secretion
-
-[Term]
 id: GO:2000861 ! regulation of estrogen secretion
 is_a: GO:2000831 {is_inferred="true"} ! regulation of steroid hormone secretion
 
@@ -97762,23 +93708,6 @@
 is_a: GO:2000867 {is_inferred="true"} ! regulation of estrone secretion
 
 [Term]
-id: GO:2000870 ! regulation of progesterone secretion
-is_a: GO:2000194 {is_inferred="true"} ! regulation of female gonad development
-is_a: GO:2000831 {is_inferred="true"} ! regulation of steroid hormone secretion
-
-[Term]
-id: GO:2000871 ! negative regulation of progesterone secretion
-is_a: GO:2000195 {is_inferred="true"} ! negative regulation of female gonad development
-is_a: GO:2000832 {is_inferred="true"} ! negative regulation of steroid hormone secretion
-is_a: GO:2000870 {is_inferred="true"} ! regulation of progesterone secretion
-
-[Term]
-id: GO:2000872 ! positive regulation of progesterone secretion
-is_a: GO:2000196 {is_inferred="true"} ! positive regulation of female gonad development
-is_a: GO:2000833 {is_inferred="true"} ! positive regulation of steroid hormone secretion
-is_a: GO:2000870 {is_inferred="true"} ! regulation of progesterone secretion
-
-[Term]
 id: GO:2000873 ! regulation of histone H4 acetylation involved in response to DNA damage stimulus
 is_a: GO:0090239 {is_inferred="true"} ! regulation of histone H4 acetylation
 is_a: GO:2001020 {is_inferred="true"} ! regulation of response to DNA damage stimulus
@@ -99165,27 +95094,6 @@
 is_a: GO:2001148 {is_inferred="true"} ! regulation of dipeptide transmembrane transport
 
 [Term]
-id: GO:2001151 ! regulation of renal water transport
-is_a: GO:0032844 {is_inferred="true"} ! regulation of homeostatic process
-is_a: GO:0050878 {is_inferred="true"} ! regulation of body fluid levels
-is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
-is_a: GO:0098801 {is_inferred="true"} ! regulation of renal system process
-
-[Term]
-id: GO:2001152 ! negative regulation of renal water transport
-is_a: GO:0032845 {is_inferred="true"} ! negative regulation of homeostatic process
-is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
-is_a: GO:2001151 {is_inferred="true"} ! regulation of renal water transport
-
-[Term]
-id: GO:2001153 ! positive regulation of renal water transport
-is_a: GO:0032846 {is_inferred="true"} ! positive regulation of homeostatic process
-is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
-is_a: GO:2001151 {is_inferred="true"} ! regulation of renal water transport
-
-[Term]
 id: GO:2001154 ! regulation of glycolytic fermentation to ethanol
 is_a: GO:0010906 {is_inferred="true"} ! regulation of glucose metabolic process
 is_a: GO:0043465 {is_inferred="true"} ! regulation of fermentation
@@ -100082,3 +95990,43 @@
 id: GOCHE:51086 ! substance with chemical property
 is_a: CHEBI:24431 {is_inferred="true"} ! chemical entity
 
+[Term]
+id: UBERON:0001289 ! descending limb of loop of Henle
+is_a: UBERON:0004810 {is_inferred="true"} ! nephron tubule epithelium
+
+[Term]
+id: UBERON:0003261 ! thyroid primordium endoderm
+is_a: UBERON:0004119 {is_inferred="true"} ! endoderm-derived structure
+
+[Term]
+id: UBERON:0004134 ! proximal tubule
+is_a: UBERON:0004810 {is_inferred="true"} ! nephron tubule epithelium
+
+[Term]
+id: UBERON:0004136 ! intermediate tubule
+is_a: UBERON:0004810 {is_inferred="true"} ! nephron tubule epithelium
+
+[Term]
+id: UBERON:0005130 ! metanephric loop of Henle
+is_a: UBERON:0004810 {is_inferred="true"} ! nephron tubule epithelium
+
+[Term]
+id: UBERON:0005164 ! ascending limb of loop of Henle
+is_a: UBERON:0004810 {is_inferred="true"} ! nephron tubule epithelium
+
+[Term]
+id: UBERON:0005421 ! pectoral appendage apical ectodermal ridge
+is_a: UBERON:0004121 {is_inferred="true"} ! ectoderm-derived structure
+
+[Term]
+id: UBERON:0005422 ! pelvic appendage apical ectodermal ridge
+is_a: UBERON:0004121 {is_inferred="true"} ! ectoderm-derived structure
+
+[Term]
+id: UBERON:0005721 ! pronephric mesoderm
+is_a: UBERON:0004120 {is_inferred="true"} ! mesoderm-derived structure
+
+[Term]
+id: UBERON:0008817 ! thymus primordium endoderm
+is_a: UBERON:0004119 {is_inferred="true"} ! endoderm-derived structure
+
------------------------------------------------------------------------
r37298 | paola | 2016-11-29 05:27:40 -0800 (Tue, 29 Nov 2016) | 2 lines

GH GO:0008280 cohesin core heterodimer #12598 - work in progress - edited capable_of_part_of link

changes in entailments

------------------------------------------------------------------------
r37294 | dph | 2016-11-28 12:00:10 -0800 (Mon, 28 Nov 2016) | 2 lines

Tweaked the definition of new ubiquitin hydrolase term.

changes in entailments

------------------------------------------------------------------------
r37292 | dph | 2016-11-28 11:12:48 -0800 (Mon, 28 Nov 2016) | 2 lines

SF12830-closed

changes in entailments

------------------------------------------------------------------------
r37290 | dph | 2016-11-28 08:52:30 -0800 (Mon, 28 Nov 2016) | 2 lines

Removed exact synonym from nuclear condensin complex.

changes in entailments

------------------------------------------------------------------------
r37288 | termgenie | 2016-11-28 08:35:44 -0800 (Mon, 28 Nov 2016) | 2 lines

TermGenie commit for user: mah reviewed by dos

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37288)
+++ go_inferences.obo	(working copy)
@@ -86447,7 +86447,7 @@
 
 [Term]
 id: GO:1904519 ! protein localization to microtubule minus-end
-is_a: GO:0035372 {is_inferred="true"} ! protein localization to microtubule
+is_a: GO:1905725 {is_inferred="true"} ! protein localization to microtubule end
 
 [Term]
 id: GO:1904520 ! regulation of myofibroblast cell apoptotic process
@@ -87908,7 +87908,7 @@
 
 [Term]
 id: GO:1904825 ! protein localization to microtubule plus-end
-is_a: GO:0035372 {is_inferred="true"} ! protein localization to microtubule
+is_a: GO:1905725 {is_inferred="true"} ! protein localization to microtubule end
 
 [Term]
 id: GO:1904826 ! regulation of hydrogen sulfide biosynthetic process
@@ -92316,6 +92316,10 @@
 is_a: GO:1905722 {is_inferred="true"} ! regulation of trypanothione biosynthetic process
 
 [Term]
+id: GO:1905725 ! protein localization to microtubule end
+is_a: GO:0035372 {is_inferred="true"} ! protein localization to microtubule
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37285 | dph | 2016-11-28 05:16:08 -0800 (Mon, 28 Nov 2016) | 2 lines

Removed logical definition of obsoleted term.

changes in entailments

------------------------------------------------------------------------
r37277 | davidos | 2016-11-27 09:08:09 -0800 (Sun, 27 Nov 2016) | 1 line

Fixed accidental taxon restriction on cell bud added to budding yeast instead of fission yeast!

changes in entailments

------------------------------------------------------------------------
r37275 | davidos | 2016-11-27 07:30:34 -0800 (Sun, 27 Nov 2016) | 1 line

removed taxon constraint on virion. Needed until this Uberon ticket is fixed: https://github.com/obophenotype/uberon/issues/1297

changes in entailments

------------------------------------------------------------------------
r37258 | davidos | 2016-11-25 09:22:03 -0800 (Fri, 25 Nov 2016) | 11 lines

Fixed inconsistency for these two classes

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37258)
+++ go_inferences.obo	(working copy)
@@ -5282,6 +5282,10 @@
 is_a: GO:0090568 {is_inferred="true"} ! nuclear transcriptional repressor complex
 
 [Term]
+id: GO:0005694 ! chromosome
+is_a: GO:0043232 {is_inferred="true"} ! intracellular non-membrane-bounded organelle
+
+[Term]
 id: GO:0005701 ! polytene chromosome chromocenter
 is_a: GO:0010369 {is_inferred="true"} ! chromocenter
 
@@ -18079,7 +18083,6 @@
 [Term]
 id: GO:0019038 ! provirus
 is_a: GO:0019015 {is_inferred="true"} ! viral genome
-is_a: GO:0044427 {is_inferred="true"} ! chromosomal part
 
 [Term]
 id: GO:0019068 ! virion assembly
@@ -34592,6 +34595,11 @@
 is_a: GO:0019005 {is_inferred="true"} ! SCF ubiquitin ligase complex
 
 [Term]
+id: GO:0043229 ! intracellular organelle
+is_a: GO:0043226 {is_inferred="true"} ! organelle
+is_a: GO:0044424 {is_inferred="true"} ! intracellular part
+
+[Term]
 id: GO:0043230 ! extracellular organelle
 is_a: GO:0043226 {is_inferred="true"} ! organelle
 is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
@@ -61269,7 +61277,7 @@
 
 [Term]
 id: GO:0097708 ! intracellular vesicle
-is_a: GO:0044424 {is_inferred="true"} ! intracellular part
+is_a: GO:0043229 {is_inferred="true"} ! intracellular organelle
 
 [Term]
 id: GO:0097733 ! photoreceptor cell cilium
@@ -62212,7 +62220,7 @@
 is_a: GO:0098890 {is_inferred="true"} ! extrinsic component of postsynaptic membrane
 
 [Term]
-id: GO:0098894 ! extrinsic component of presynaptic endocytic zone
+id: GO:0098894 ! extrinsic component of presynaptic endocytic zone membrane
 is_a: GO:0098888 {is_inferred="true"} ! extrinsic component of presynaptic membrane
 
 [Term]
@@ -62838,11 +62846,8 @@
 
 [Term]
 id: GO:0099065 ! integral component of spine apparatus membrane
-is_a: GO:0016021 {is_inferred="true"} ! integral component of membrane
-is_a: GO:0044422 {is_inferred="true"} ! organelle part
-is_a: GO:0044456 {is_inferred="true"} ! synapse part
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
-is_a: GO:0097458 {is_inferred="true"} ! neuron part
+is_a: GO:0031301 {is_inferred="true"} ! integral component of organelle membrane
+is_a: GO:0098952 {is_inferred="true"} ! intrinsic component of spine apparatus membrane
 
 [Term]
 id: GO:0099066 ! integral component of neuronal dense core vesicle membrane
@@ -63023,6 +63028,11 @@
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
+id: GO:0099113 ! negative regulation of presynaptic cytosolic calcium concentration
+is_a: GO:0051481 {is_inferred="true"} ! negative regulation of cytosolic calcium ion concentration
+is_a: GO:0099509 {is_inferred="true"} ! regulation of presynaptic cytosolic calcium ion concentration
+
+[Term]
 id: GO:0099400 ! caveola neck
 is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
 
@@ -83421,7 +83431,9 @@
 [Term]
 id: GO:1903916 ! regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation
 is_a: GO:0006446 {is_inferred="true"} ! regulation of translational initiation
+is_a: GO:0032535 {is_inferred="true"} ! regulation of cellular component size
 is_a: GO:0035304 {is_inferred="true"} ! regulation of protein dephosphorylation
+is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
 
 [Term]
@@ -83428,6 +83440,7 @@
 id: GO:1903917 ! positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation
 is_a: GO:0035307 {is_inferred="true"} ! positive regulation of protein dephosphorylation
 is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
+is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 is_a: GO:1903916 {is_inferred="true"} ! regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation
 
 [Term]
------------------------------------------------------------------------
r37255 | termgenie | 2016-11-25 07:54:29 -0800 (Fri, 25 Nov 2016) | 3 lines

Changed my mind about these terms.  WIll add slightly more specific ones instead. TermGenie commit for user: dos reviewed by dos

changes in entailments

------------------------------------------------------------------------
r37253 | termgenie | 2016-11-25 07:25:34 -0800 (Fri, 25 Nov 2016) | 4 lines

TermGenie commit for user: rz reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37253)
+++ go_inferences.obo	(working copy)
@@ -92278,6 +92278,31 @@
 is_a: GO:0097427 {is_inferred="true"} ! microtubule bundle
 
 [Term]
+id: GO:1905721 ! mitotic spindle astral microtubule end
+is_a: GO:0044444 {is_inferred="true"} ! cytoplasmic part
+is_a: GO:1990752 {is_inferred="true"} ! microtubule end
+
+[Term]
+id: GO:1905722 ! regulation of trypanothione biosynthetic process
+is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
+is_a: GO:0042762 {is_inferred="true"} ! regulation of sulfur metabolic process
+is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
+
+[Term]
+id: GO:1905723 ! negative regulation of trypanothione biosynthetic process
+is_a: GO:0031327 {is_inferred="true"} ! negative regulation of cellular biosynthetic process
+is_a: GO:0051172 {is_inferred="true"} ! negative regulation of nitrogen compound metabolic process
+is_a: GO:0051175 {is_inferred="true"} ! negative regulation of sulfur metabolic process
+is_a: GO:1905722 {is_inferred="true"} ! regulation of trypanothione biosynthetic process
+
+[Term]
+id: GO:1905724 ! positive regulation of trypanothione biosynthetic process
+is_a: GO:0031328 {is_inferred="true"} ! positive regulation of cellular biosynthetic process
+is_a: GO:0051173 {is_inferred="true"} ! positive regulation of nitrogen compound metabolic process
+is_a: GO:0051176 {is_inferred="true"} ! positive regulation of sulfur metabolic process
+is_a: GO:1905722 {is_inferred="true"} ! regulation of trypanothione biosynthetic process
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37246 | mcourtot | 2016-11-25 03:13:25 -0800 (Fri, 25 Nov 2016) | 1 line

merged GO:0001157 and GO:0001005 as per https://github.com/geneontology/go-ontology/issues/12821

changes in entailments

------------------------------------------------------------------------
r37244 | termgenie | 2016-11-25 02:56:02 -0800 (Fri, 25 Nov 2016) | 3 lines

TermGenie commit for user: mah reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37244)
+++ go_inferences.obo	(working copy)
@@ -92269,6 +92269,15 @@
 is_a: GO:1905715 {is_inferred="true"} ! regulation of cornification
 
 [Term]
+id: GO:1905719 ! protein localization to perinuclear region of cytoplasm
+is_a: GO:0008104 {is_inferred="true"} ! protein localization
+
+[Term]
+id: GO:1905720 ! cytoplasmic microtubule bundle
+is_a: GO:0044444 {is_inferred="true"} ! cytoplasmic part
+is_a: GO:0097427 {is_inferred="true"} ! microtubule bundle
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37240 | davidos | 2016-11-24 11:47:40 -0800 (Thu, 24 Nov 2016) | 1 line

removed EC def on GO:0048312 ; intracellular distribution of mitochondria in order to get build to pass. Should investigate merging with parent class.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37240)
+++ go_inferences.obo	(working copy)
@@ -8237,6 +8237,10 @@
 is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
 [Term]
+id: GO:0007017 ! microtubule-based process
+is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
+
+[Term]
 id: GO:0007026 ! negative regulation of microtubule depolymerization
 is_a: GO:0031111 {is_inferred="true"} ! negative regulation of microtubule polymerization or depolymerization
 is_a: GO:0031114 {is_inferred="true"} ! regulation of microtubule depolymerization
@@ -13958,6 +13962,7 @@
 [Term]
 id: GO:0010970 ! transport along microtubule
 is_a: GO:0030705 {is_inferred="true"} ! cytoskeleton-dependent intracellular transport
+is_a: GO:0099111 {is_inferred="true"} ! microtubule-based transport
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
@@ -16858,7 +16863,6 @@
 
 [Term]
 id: GO:0016079 ! synaptic vesicle exocytosis
-is_a: GO:0099003 {is_inferred="true"} ! vesicle-mediated transport in synapse
 is_a: GO:0099531 {is_inferred="true"} ! presynaptic process involved in chemical synaptic transmission
 is_a: GO:0099643 {is_inferred="true"} ! signal release from synapse
 
@@ -17150,7 +17154,7 @@
 
 [Term]
 id: GO:0016182 ! synaptic vesicle budding from endosome
-is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
+is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
 is_a: GO:0070142 {is_inferred="true"} ! synaptic vesicle budding
 is_a: GO:0099003 {is_inferred="true"} ! vesicle-mediated transport in synapse
 
@@ -29413,6 +29417,10 @@
 is_a: GO:0015562 {is_inferred="true"} ! efflux transmembrane transporter activity
 
 [Term]
+id: GO:0034640 ! establishment of mitochondrion localization by microtubule attachment
+is_a: GO:0099098 {is_inferred="true"} ! microtubule polymerization based movement
+
+[Term]
 id: GO:0034642 ! mitochondrion migration along actin filament
 is_a: GO:0099515 {is_inferred="true"} ! actin filament-based transport
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
@@ -29419,6 +29427,7 @@
 
 [Term]
 id: GO:0034643 ! establishment of mitochondrion localization, microtubule-mediated
+is_a: GO:0051654 {is_inferred="true"} ! establishment of mitochondrion localization
 is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 
 [Term]
@@ -31538,10 +31547,6 @@
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
-id: GO:0036465 ! synaptic vesicle recycling
-is_a: GO:0099003 {is_inferred="true"} ! vesicle-mediated transport in synapse
-
-[Term]
 id: GO:0036502 ! Derlin-1-VIMP complex
 is_a: GO:0044432 {is_inferred="true"} ! endoplasmic reticulum part
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
@@ -42896,6 +42901,11 @@
 is_a: GO:0099518 {is_inferred="true"} ! vesicle cytoskeletal trafficking
 
 [Term]
+id: GO:0047497 ! mitochondrion transport along microtubule
+is_a: GO:0034643 {is_inferred="true"} ! establishment of mitochondrion localization, microtubule-mediated
+is_a: GO:0072384 {is_inferred="true"} ! organelle transport along microtubule
+
+[Term]
 id: GO:0048018 ! receptor agonist activity
 is_a: GO:0004871 {is_inferred="true"} ! signal transducer activity
 
@@ -43180,9 +43190,8 @@
 
 [Term]
 id: GO:0048206 ! vesicle targeting, cis-Golgi to rough ER
-is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
 is_a: GO:0051650 {is_inferred="true"} ! establishment of vesicle localization
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:0048208 ! COPII vesicle coating
@@ -43355,10 +43364,6 @@
 is_a: GO:0048308 {is_inferred="true"} ! organelle inheritance
 
 [Term]
-id: GO:0048312 ! intracellular distribution of mitochondria
-is_a: GO:0048311 {is_inferred="true"} ! mitochondrion distribution
-
-[Term]
 id: GO:0048313 ! Golgi inheritance
 is_a: GO:0048308 {is_inferred="true"} ! organelle inheritance
 
@@ -43645,13 +43650,14 @@
 
 [Term]
 id: GO:0048488 ! synaptic vesicle endocytosis
-is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
+is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
 is_a: GO:0099003 {is_inferred="true"} ! vesicle-mediated transport in synapse
 
 [Term]
 id: GO:0048489 ! synaptic vesicle transport
 is_a: GO:0097479 {is_inferred="true"} ! synaptic vesicle localization
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
+is_a: GO:0099003 {is_inferred="true"} ! vesicle-mediated transport in synapse
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:0048490 ! anterograde synaptic vesicle transport
@@ -47191,6 +47197,8 @@
 [Term]
 id: GO:0051654 ! establishment of mitochondrion localization
 is_a: GO:0051646 {is_inferred="true"} ! mitochondrion localization
+is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
+is_a: GO:0051656 {is_inferred="true"} ! establishment of organelle localization
 
 [Term]
 id: GO:0051655 ! maintenance of vesicle location
@@ -47609,7 +47617,7 @@
 [Term]
 id: GO:0051904 ! pigment granule transport
 is_a: GO:0051875 {is_inferred="true"} ! pigment granule localization
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:0051917 ! regulation of fibrinolysis
@@ -51887,6 +51895,7 @@
 
 [Term]
 id: GO:0061707 ! extracellular exosome macropinocytosis
+is_a: GO:0006858 {is_inferred="true"} ! extracellular transport
 is_a: GO:0051650 {is_inferred="true"} ! establishment of vesicle localization
 is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 
@@ -60733,7 +60742,7 @@
 
 [Term]
 id: GO:0097120 ! receptor localization to synapse
-is_a: GO:0051179 {is_inferred="true"} ! localization
+is_a: GO:0051668 {is_inferred="true"} ! localization within membrane
 
 [Term]
 id: GO:0097149 ! centralspindlin complex
@@ -62941,6 +62950,10 @@
 is_a: GO:0044091 {is_inferred="true"} ! membrane biogenesis
 
 [Term]
+id: GO:0099098 ! microtubule polymerization based movement
+is_a: GO:0007018 {is_inferred="true"} ! microtubule-based movement
+
+[Term]
 id: GO:0099099 ! G-protein gated ion channel activity
 is_a: GO:0005216 {is_inferred="true"} ! ion channel activity
 
@@ -62991,6 +63004,25 @@
 is_a: GO:0099105 {is_inferred="true"} ! ion channel modulating, G-protein coupled receptor signaling pathway
 
 [Term]
+id: GO:0099110 ! microtubule polymerization based protein transport to cell tip cortex
+is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
+is_a: GO:0099112 {is_inferred="true"} ! microtubule polymerization based protein transport
+is_a: GO:1990896 {is_inferred="true"} ! protein localization to cell cortex of cell tip
+
+[Term]
+id: GO:0099111 ! microtubule-based transport
+is_a: GO:0007018 {is_inferred="true"} ! microtubule-based movement
+is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
+
+[Term]
+id: GO:0099112 ! microtubule polymerization based protein transport
+is_a: GO:0045184 {is_inferred="true"} ! establishment of protein localization
+is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
+is_a: GO:0099098 {is_inferred="true"} ! microtubule polymerization based movement
+is_a: GO:0099111 {is_inferred="true"} ! microtubule-based transport
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
+
+[Term]
 id: GO:0099400 ! caveola neck
 is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
 
@@ -63030,7 +63062,6 @@
 id: GO:0099514 ! synaptic vesicle cytoskeletal transport
 is_a: GO:0048489 {is_inferred="true"} ! synaptic vesicle transport
 is_a: GO:0099518 {is_inferred="true"} ! vesicle cytoskeletal trafficking
-is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:0099515 ! actin filament-based transport
@@ -63236,6 +63267,10 @@
 is_a: GO:0099566 {is_inferred="true"} ! regulation of postsynaptic cytosolic calcium ion concentration
 
 [Term]
+id: GO:0099592 ! endocytosed synaptic vesicle processing via endosome
+is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
+
+[Term]
 id: GO:0099601 ! regulation of neurotransmitter receptor activity
 is_a: GO:0010469 {is_inferred="true"} ! regulation of receptor activity
 
@@ -77446,7 +77481,7 @@
 
 [Term]
 id: GO:1902683 ! regulation of receptor localization to synapse
-is_a: GO:0032879 {is_inferred="true"} ! regulation of localization
+is_a: GO:0060341 {is_inferred="true"} ! regulation of cellular localization
 
 [Term]
 id: GO:1902684 ! negative regulation of receptor localization to synapse
@@ -77985,17 +78020,17 @@
 
 [Term]
 id: GO:1902803 ! regulation of synaptic vesicle transport
-is_a: GO:0060341 {is_inferred="true"} ! regulation of cellular localization
+is_a: GO:0032386 {is_inferred="true"} ! regulation of intracellular transport
 is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
 
 [Term]
 id: GO:1902804 ! negative regulation of synaptic vesicle transport
-is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
+is_a: GO:0032387 {is_inferred="true"} ! negative regulation of intracellular transport
 is_a: GO:1902803 {is_inferred="true"} ! regulation of synaptic vesicle transport
 
 [Term]
 id: GO:1902805 ! positive regulation of synaptic vesicle transport
-is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
+is_a: GO:0032388 {is_inferred="true"} ! positive regulation of intracellular transport
 is_a: GO:1902803 {is_inferred="true"} ! regulation of synaptic vesicle transport
 
 [Term]
@@ -78511,20 +78546,19 @@
 
 [Term]
 id: GO:1902908 ! regulation of melanosome transport
+is_a: GO:0032386 {is_inferred="true"} ! regulation of intracellular transport
 is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
-is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
-is_a: GO:0060341 {is_inferred="true"} ! regulation of cellular localization
 
 [Term]
 id: GO:1902909 ! negative regulation of melanosome transport
+is_a: GO:0032387 {is_inferred="true"} ! negative regulation of intracellular transport
 is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
-is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
 is_a: GO:1902908 {is_inferred="true"} ! regulation of melanosome transport
 
 [Term]
 id: GO:1902910 ! positive regulation of melanosome transport
+is_a: GO:0032388 {is_inferred="true"} ! positive regulation of intracellular transport
 is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
-is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
 is_a: GO:1902908 {is_inferred="true"} ! regulation of melanosome transport
 
 [Term]
@@ -93067,6 +93101,7 @@
 
 [Term]
 id: GO:1990771 ! clathrin-dependent extracellular exosome endocytosis
+is_a: GO:0006858 {is_inferred="true"} ! extracellular transport
 is_a: GO:0051650 {is_inferred="true"} ! establishment of vesicle localization
 
 [Term]
------------------------------------------------------------------------
r37237 | paola | 2016-11-24 08:48:03 -0800 (Thu, 24 Nov 2016) | 3 lines

GH NTR: vasodilation by nitric oxide #12253 - work in progress - edited and rehoused ’vasoconstriction’ and ‘vasodilation’

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37237)
+++ go_inferences.obo	(working copy)
@@ -18169,7 +18169,7 @@
 
 [Term]
 id: GO:0019229 ! regulation of vasoconstriction
-is_a: GO:0050880 {is_inferred="true"} ! regulation of blood vessel size
+is_a: GO:0097746 {is_inferred="true"} ! regulation of blood vessel diameter
 is_a: GO:1903522 {is_inferred="true"} ! regulation of blood circulation
 
 [Term]
@@ -32536,7 +32536,7 @@
 
 [Term]
 id: GO:0042312 ! regulation of vasodilation
-is_a: GO:0050880 {is_inferred="true"} ! regulation of blood vessel size
+is_a: GO:0097746 {is_inferred="true"} ! regulation of blood vessel diameter
 is_a: GO:1903522 {is_inferred="true"} ! regulation of blood circulation
 
 [Term]
------------------------------------------------------------------------
r37235 | paola | 2016-11-24 08:26:58 -0800 (Thu, 24 Nov 2016) | 3 lines

GH NTR: vasodilation by nitric oxide #12253 - work in progress - edited ‘regulation of blood vessel size by renin-angiotensin’ node

changes in entailments

------------------------------------------------------------------------
r37233 | paola | 2016-11-24 07:49:57 -0800 (Thu, 24 Nov 2016) | 2 lines

GH NTR: vasodilation by nitric oxide #12253 - work in progress - added GO:0097746 regulation of blood vessel diameter

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37233)
+++ go_inferences.obo	(working copy)
@@ -61279,6 +61279,10 @@
 is_a: GO:0034471 {is_inferred="true"} ! ncRNA 5'-end processing
 
 [Term]
+id: GO:0097746 ! regulation of blood vessel diameter
+is_a: GO:0050880 {is_inferred="true"} ! regulation of blood vessel size
+
+[Term]
 id: GO:0098003 ! viral tail assembly
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
 
------------------------------------------------------------------------
r37226 | termgenie | 2016-11-24 06:52:21 -0800 (Thu, 24 Nov 2016) | 4 lines

TermGenie commit for user: pga reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37226)
+++ go_inferences.obo	(working copy)
@@ -92214,6 +92214,23 @@
 is_a: GO:1905711 {is_inferred="true"} ! response to phosphatidylethanolamine
 
 [Term]
+id: GO:1905715 ! regulation of cornification
+is_a: GO:0043067 {is_inferred="true"} ! regulation of programmed cell death
+is_a: GO:0045616 {is_inferred="true"} ! regulation of keratinocyte differentiation
+
+[Term]
+id: GO:1905716 ! negative regulation of cornification
+is_a: GO:0043069 {is_inferred="true"} ! negative regulation of programmed cell death
+is_a: GO:0045617 {is_inferred="true"} ! negative regulation of keratinocyte differentiation
+is_a: GO:1905715 {is_inferred="true"} ! regulation of cornification
+
+[Term]
+id: GO:1905717 ! positive regulation of cornification
+is_a: GO:0043068 {is_inferred="true"} ! positive regulation of programmed cell death
+is_a: GO:0045618 {is_inferred="true"} ! positive regulation of keratinocyte differentiation
+is_a: GO:1905715 {is_inferred="true"} ! regulation of cornification
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37224 | termgenie | 2016-11-24 06:44:00 -0800 (Thu, 24 Nov 2016) | 2 lines

TermGenie commit for user: vw reviewed by pr

changes in entailments

------------------------------------------------------------------------
r37222 | davidos | 2016-11-24 04:29:52 -0800 (Thu, 24 Nov 2016) | 1 line

fixed duplicate defs (Add check for identical definitions in ontology file? (#12815))

changes in entailments

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r37220 | mcourtot | 2016-11-24 01:12:59 -0800 (Thu, 24 Nov 2016) | 1 line

fixed duplicate def - closes https://github.com/geneontology/go-ontology/issues/12817

changes in entailments

------------------------------------------------------------------------
r37215 | tberardi | 2016-11-23 16:43:36 -0800 (Wed, 23 Nov 2016) | 1 line

Fine. Added back the technically incorrect former primary term name of the merged term because of Jenkins complaint about Missing primary label for merged term: delta5-delta2,4-dienoyl-CoA isomerase activity GO:0008416

changes in entailments

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r37210 | tberardi | 2016-11-23 14:54:19 -0800 (Wed, 23 Nov 2016) | 1 line

cleaning up duplicate definitions part 2

changes in entailments

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r37208 | tberardi | 2016-11-23 14:12:10 -0800 (Wed, 23 Nov 2016) | 1 line

cleaning up duplicate definitions

changes in entailments

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r37206 | tberardi | 2016-11-23 12:35:37 -0800 (Wed, 23 Nov 2016) | 1 line

GH12802 Update of EC mappings - closed

changes in entailments

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r37203 | mcourtot | 2016-11-23 08:39:56 -0800 (Wed, 23 Nov 2016) | 1 line

fixed few duplicate defs

changes in entailments

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r37201 | mcourtot | 2016-11-23 08:29:34 -0800 (Wed, 23 Nov 2016) | 1 line

dded is a parent for GO:0000799

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37201)
+++ go_inferences.obo	(working copy)
@@ -912,7 +912,6 @@
 
 [Term]
 id: GO:0000797 ! condensin core heterodimer
-is_a: GO:0043234 {is_inferred="true"} ! protein complex
 is_a: GO:0044427 {is_inferred="true"} ! chromosomal part
 
 [Term]
@@ -922,7 +921,6 @@
 
 [Term]
 id: GO:0000799 ! nuclear condensin complex
-is_a: GO:0000796 {is_inferred="true"} ! condensin complex
 is_a: GO:0044454 {is_inferred="true"} ! nuclear chromosome part
 
 [Term]
------------------------------------------------------------------------
r37191 | mcourtot | 2016-11-23 06:57:10 -0800 (Wed, 23 Nov 2016) | 1 line

fixed few duplicate defs

changes in entailments

------------------------------------------------------------------------
r37189 | mcourtot | 2016-11-23 06:52:50 -0800 (Wed, 23 Nov 2016) | 1 line

fixed few duplicate defs

changes in entailments

------------------------------------------------------------------------
r37188 | davidos | 2016-11-23 06:48:27 -0800 (Wed, 23 Nov 2016) | 1 line

Synpase: Annotation of mitochondrial Ca2+ pumps/antiporters #63 - partially fixed. Will do remainder in TG

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37188)
+++ go_inferences.obo	(working copy)
@@ -31532,8 +31532,9 @@
 is_a: GO:0045203 {is_inferred="true"} ! integral component of cell outer membrane
 
 [Term]
-id: GO:0036444 ! calcium ion transmembrane import into mitochondrion
+id: GO:0036444 ! mitochondrial calcium uptake
 is_a: GO:0006851 {is_inferred="true"} ! mitochondrial calcium ion transport
+is_a: GO:0060401 {is_inferred="true"} ! cytosolic calcium ion transport
 is_a: GO:0070509 {is_inferred="true"} ! calcium ion import
 is_a: GO:0070588 {is_inferred="true"} ! calcium ion transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
@@ -62915,6 +62916,13 @@
 is_a: GO:0044464 {is_inferred="true"} ! cell part
 
 [Term]
+id: GO:0099093 ! mitochondrial calcium release
+is_a: GO:0006851 {is_inferred="true"} ! mitochondrial calcium ion transport
+is_a: GO:0051209 {is_inferred="true"} ! release of sequestered calcium ion into cytosol
+is_a: GO:1901660 {is_inferred="true"} ! calcium ion export
+is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
+
+[Term]
 id: GO:0099094 ! ligand-gated cation channel activity
 is_a: GO:0005261 {is_inferred="true"} ! cation channel activity
 is_a: GO:0015276 {is_inferred="true"} ! ligand-gated ion channel activity
------------------------------------------------------------------------
r37186 | paola | 2016-11-23 06:16:53 -0800 (Wed, 23 Nov 2016) | 2 lines

Removed RO stanzas

changes in entailments

------------------------------------------------------------------------
r37183 | mcourtot | 2016-11-23 06:06:01 -0800 (Wed, 23 Nov 2016) | 1 line

fixed few duplicate defs

changes in entailments

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r37177 | paola | 2016-11-23 03:53:01 -0800 (Wed, 23 Nov 2016) | 2 lines

Removed RO stanzas

changes in entailments

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r37172 | tberardi | 2016-11-22 16:24:30 -0800 (Tue, 22 Nov 2016) | 1 line

GH12803 cortical dynamic polarity patch - closed

changes in entailments

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r37170 | tberardi | 2016-11-22 15:25:40 -0800 (Tue, 22 Nov 2016) | 1 line

GH12766 Review MF term GO:0050827 toxin receptor binding - removed synonyms

changes in entailments

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r37168 | tberardi | 2016-11-22 15:05:17 -0800 (Tue, 22 Nov 2016) | 1 line

GH12797 def of cellular localization, odd - closed

changes in entailments

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r37166 | davidos | 2016-11-22 14:38:09 -0800 (Tue, 22 Nov 2016) | 1 line

More work on viralzone terms (cleanup). (New phage terms mapping to SPKW/ViralZone #11426).  Fixed bad logical def on pH gated chloride channel

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37166)
+++ go_inferences.obo	(working copy)
@@ -4878,14 +4878,9 @@
 
 [Term]
 id: GO:0005224 ! ATP-binding and phosphorylation-dependent chloride channel activity
-is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
 is_a: GO:0099095 {is_inferred="true"} ! ligand-gated anion channel activity
 
 [Term]
-id: GO:0005229 ! intracellular calcium activated chloride channel activity
-is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
-
-[Term]
 id: GO:0005242 ! inward rectifier potassium channel activity
 is_a: GO:0099094 {is_inferred="true"} ! ligand-gated cation channel activity
 
@@ -4894,10 +4889,6 @@
 is_a: GO:0099106 {is_inferred="true"} ! ion channel regulator activity
 
 [Term]
-id: GO:0005247 ! voltage-gated chloride channel activity
-is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
-
-[Term]
 id: GO:0005274 ! allantoin uptake transmembrane transporter activity
 is_a: GO:0015563 {is_inferred="true"} ! uptake transmembrane transporter activity
 is_a: GO:0042887 {is_inferred="true"} ! amide transmembrane transporter activity
@@ -8819,7 +8810,6 @@
 
 [Term]
 id: GO:0008068 ! extracellular-glutamate-gated chloride channel activity
-is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
 is_a: GO:0099095 {is_inferred="true"} ! ligand-gated anion channel activity
 
 [Term]
@@ -17389,7 +17379,6 @@
 
 [Term]
 id: GO:0016934 ! extracellular-glycine-gated chloride channel activity
-is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
 is_a: GO:0099095 {is_inferred="true"} ! ligand-gated anion channel activity
 
 [Term]
@@ -18120,7 +18109,6 @@
 
 [Term]
 id: GO:0019182 ! histamine-gated chloride channel activity
-is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
 is_a: GO:0099095 {is_inferred="true"} ! ligand-gated anion channel activity
 
 [Term]
@@ -20490,13 +20478,13 @@
 
 [Term]
 id: GO:0022851 ! GABA-gated chloride ion channel activity
+is_a: GO:0005254 {is_inferred="true"} ! chloride channel activity
 is_a: GO:0016917 {is_inferred="true"} ! GABA receptor activity
-is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
 is_a: GO:0099095 {is_inferred="true"} ! ligand-gated anion channel activity
 
 [Term]
 id: GO:0022852 ! glycine-gated chloride ion channel activity
-is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
+is_a: GO:0005254 {is_inferred="true"} ! chloride channel activity
 is_a: GO:0099095 {is_inferred="true"} ! ligand-gated anion channel activity
 
 [Term]
@@ -63020,6 +63008,7 @@
 
 [Term]
 id: GO:0099509 ! regulation of presynaptic cytosolic calcium ion concentration
+is_a: GO:0051480 {is_inferred="true"} ! regulation of cytosolic calcium ion concentration
 is_a: GO:0070050 {is_inferred="true"} ! neuron cellular homeostasis
 
 [Term]
@@ -63095,6 +63084,7 @@
 
 [Term]
 id: GO:0099533 ! positive regulation of presynaptic cytosolic calcium concentration
+is_a: GO:0007204 {is_inferred="true"} ! positive regulation of cytosolic calcium ion concentration
 is_a: GO:0099509 {is_inferred="true"} ! regulation of presynaptic cytosolic calcium ion concentration
 
 [Term]
@@ -63232,6 +63222,7 @@
 
 [Term]
 id: GO:0099588 ! positive regulation of postsynaptic cytosolic calcium concentration
+is_a: GO:0007204 {is_inferred="true"} ! positive regulation of cytosolic calcium ion concentration
 is_a: GO:0099566 {is_inferred="true"} ! regulation of postsynaptic cytosolic calcium ion concentration
 
 [Term]
------------------------------------------------------------------------
r37163 | dph | 2016-11-22 10:53:25 -0800 (Tue, 22 Nov 2016) | 2 lines

Changed autolysosome to lysosome in the chaperone-mediated authophagy axioms.

changes in entailments

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r37159 | dph | 2016-11-22 06:50:03 -0800 (Tue, 22 Nov 2016) | 2 lines

Added autolysosome as a participant in chaperone-mediated autophagy. 

changes in entailments

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r37157 | dph | 2016-11-22 06:03:03 -0800 (Tue, 22 Nov 2016) | 2 lines

GH12792-closed

changes in entailments

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r37151 | paola | 2016-11-22 03:15:40 -0800 (Tue, 22 Nov 2016) | 2 lines

Removed RO stanzas

changes in entailments

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r37148 | paola | 2016-11-22 03:04:06 -0800 (Tue, 22 Nov 2016) | 2 lines

Removed RO stanzas

changes in entailments

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r37140 | tberardi | 2016-11-21 13:14:45 -0800 (Mon, 21 Nov 2016) | 1 line

fixed negative/positive regulation of regulation of X terms to be just regulation of x terms, were ROBQ terms added through TermGenie

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37140)
+++ go_inferences.obo	(working copy)
@@ -69208,7 +69208,6 @@
 is_a: GO:0010823 {is_inferred="true"} ! negative regulation of mitochondrion organization
 is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
 is_a: GO:1901028 {is_inferred="true"} ! regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
-is_a: GO:1905709 {is_inferred="true"} ! negative regulation of regulation of membrane permeability
 is_a: GO:2001234 {is_inferred="true"} ! negative regulation of apoptotic signaling pathway
 
 [Term]
@@ -69216,7 +69215,6 @@
 is_a: GO:0010822 {is_inferred="true"} ! positive regulation of mitochondrion organization
 is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
 is_a: GO:1901028 {is_inferred="true"} ! regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
-is_a: GO:1905710 {is_inferred="true"} ! positive regulation of regulation of membrane permeability
 is_a: GO:2001235 {is_inferred="true"} ! positive regulation of apoptotic signaling pathway
 
 [Term]
@@ -92207,16 +92205,6 @@
 is_a: GO:0048583 {is_inferred="true"} ! regulation of response to stimulus
 
 [Term]
-id: GO:1905709 ! negative regulation of regulation of membrane permeability
-is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
-is_a: GO:0065008 {is_inferred="true"} ! regulation of biological quality
-
-[Term]
-id: GO:1905710 ! positive regulation of regulation of membrane permeability
-is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
-is_a: GO:0065008 {is_inferred="true"} ! regulation of biological quality
-
-[Term]
 id: GO:1905711 ! response to phosphatidylethanolamine
 is_a: GO:0033993 {is_inferred="true"} ! response to lipid
 is_a: GO:0046683 {is_inferred="true"} ! response to organophosphorus
------------------------------------------------------------------------
r37138 | termgenie | 2016-11-21 13:05:32 -0800 (Mon, 21 Nov 2016) | 3 lines

TermGenie commit for user: sl reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37138)
+++ go_inferences.obo	(working copy)
@@ -92217,6 +92217,18 @@
 is_a: GO:0065008 {is_inferred="true"} ! regulation of biological quality
 
 [Term]
+id: GO:1905711 ! response to phosphatidylethanolamine
+is_a: GO:0033993 {is_inferred="true"} ! response to lipid
+is_a: GO:0046683 {is_inferred="true"} ! response to organophosphorus
+is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
+
+[Term]
+id: GO:1905712 ! cellular response to phosphatidylethanolamine
+is_a: GO:0071396 {is_inferred="true"} ! cellular response to lipid
+is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
+is_a: GO:1905711 {is_inferred="true"} ! response to phosphatidylethanolamine
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37133 | termgenie | 2016-11-21 09:58:24 -0800 (Mon, 21 Nov 2016) | 2 lines

TermGenie commit for user: pg reviewed by tb https://github.com/geneontology/go-ontology/issues/12806

changes in entailments

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r37128 | davidos | 2016-11-21 08:46:35 -0800 (Mon, 21 Nov 2016) | 1 line

Fixed myosin phosphatase regulator activity logical def + related logical defs to => correct inferred classification

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37128)
+++ go_inferences.obo	(working copy)
@@ -17399,8 +17399,7 @@
 
 [Term]
 id: GO:0017020 ! myosin phosphatase regulator activity
-is_a: GO:0004721 {is_inferred="true"} ! phosphoprotein phosphatase activity
-is_a: GO:0030234 {is_inferred="true"} ! enzyme regulator activity
+is_a: GO:0019888 {is_inferred="true"} ! protein phosphatase regulator activity
 
 [Term]
 id: GO:0017038 ! protein import
@@ -18143,9 +18142,20 @@
 
 [Term]
 id: GO:0019209 ! kinase activator activity
+is_a: GO:0008047 {is_inferred="true"} ! enzyme activator activity
 is_a: GO:0019207 {is_inferred="true"} ! kinase regulator activity
 
 [Term]
+id: GO:0019211 ! phosphatase activator activity
+is_a: GO:0008047 {is_inferred="true"} ! enzyme activator activity
+is_a: GO:0019208 {is_inferred="true"} ! phosphatase regulator activity
+
+[Term]
+id: GO:0019212 ! phosphatase inhibitor activity
+is_a: GO:0004857 {is_inferred="true"} ! enzyme inhibitor activity
+is_a: GO:0019208 {is_inferred="true"} ! phosphatase regulator activity
+
+[Term]
 id: GO:0019216 ! regulation of lipid metabolic process
 is_a: GO:0080090 {is_inferred="true"} ! regulation of primary metabolic process
 
@@ -20034,6 +20044,10 @@
 is_a: GO:0046451 {is_inferred="true"} ! diaminopimelate metabolic process
 
 [Term]
+id: GO:0019888 ! protein phosphatase regulator activity
+is_a: GO:0019208 {is_inferred="true"} ! phosphatase regulator activity
+
+[Term]
 id: GO:0019889 ! pteridine metabolic process
 is_a: GO:0042558 {is_inferred="true"} ! pteridine-containing compound metabolic process
 
@@ -57255,6 +57269,11 @@
 is_a: GO:0098802 {is_inferred="true"} ! plasma membrane receptor complex
 
 [Term]
+id: GO:0072542 ! protein phosphatase activator activity
+is_a: GO:0019211 {is_inferred="true"} ! phosphatase activator activity
+is_a: GO:0019888 {is_inferred="true"} ! protein phosphatase regulator activity
+
+[Term]
 id: GO:0072544 ! L-DOPA binding
 is_a: GO:0016597 {is_inferred="true"} ! amino acid binding
 is_a: GO:0072341 {is_inferred="true"} ! modified amino acid binding
------------------------------------------------------------------------
r37121 | paola | 2016-11-21 08:15:46 -0800 (Mon, 21 Nov 2016) | 3 lines

GH OTR: Align GO and Reactome on ciliary processes #12487 - closed - added taxon rules to ‘cilium’ and ‘cilium assembly’

changes in entailments

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r37121 | paola | 2016-11-21 08:15:46 -0800 (Mon, 21 Nov 2016) | 3 lines

GH OTR: Align GO and Reactome on ciliary processes #12487 - closed - added taxon rules to ‘cilium’ and ‘cilium assembly’

changes in entailments

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r37117 | paola | 2016-11-21 07:09:39 -0800 (Mon, 21 Nov 2016) | 2 lines

Deleting ghost RO stanzas

changes in entailments

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r37115 | paola | 2016-11-21 06:42:46 -0800 (Mon, 21 Nov 2016) | 3 lines

GH some synonyms for "epithelial cilium movement" terms #12804 - closed - added synonyms, see ticket for details

changes in entailments

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r37113 | paola | 2016-11-21 06:17:09 -0800 (Mon, 21 Nov 2016) | 3 lines

GH NTRs for ciliary CC terms: paraflagellar rod and mastigoneme #12733 - closed - added taxon rule to ‘mastigoneme’.

changes in entailments

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r37111 | davidos | 2016-11-21 05:16:16 -0800 (Mon, 21 Nov 2016) | 1 line

tidying up to fix build

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37111)
+++ go_inferences.obo	(working copy)
@@ -4836,6 +4836,10 @@
 is_a: GO:0004871 {is_inferred="true"} ! signal transducer activity
 
 [Term]
+id: GO:0004857 ! enzyme inhibitor activity
+is_a: GO:0030234 {is_inferred="true"} ! enzyme regulator activity
+
+[Term]
 id: GO:0004879 ! RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
 is_a: GO:0004871 {is_inferred="true"} ! signal transducer activity
 
@@ -4848,6 +4852,10 @@
 is_a: GO:0038023 {is_inferred="true"} ! signaling receptor activity
 
 [Term]
+id: GO:0004972 ! NMDA glutamate receptor activity
+is_a: GO:0099094 {is_inferred="true"} ! ligand-gated cation channel activity
+
+[Term]
 id: GO:0004993 ! G-protein coupled serotonin receptor activity
 is_a: GO:0008227 {is_inferred="true"} ! G-protein coupled amine receptor activity
 is_a: GO:0099589 {is_inferred="true"} ! serotonin receptor activity
@@ -4871,6 +4879,7 @@
 [Term]
 id: GO:0005224 ! ATP-binding and phosphorylation-dependent chloride channel activity
 is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
+is_a: GO:0099095 {is_inferred="true"} ! ligand-gated anion channel activity
 
 [Term]
 id: GO:0005229 ! intracellular calcium activated chloride channel activity
@@ -4877,6 +4886,14 @@
 is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
 
 [Term]
+id: GO:0005242 ! inward rectifier potassium channel activity
+is_a: GO:0099094 {is_inferred="true"} ! ligand-gated cation channel activity
+
+[Term]
+id: GO:0005246 ! calcium channel regulator activity
+is_a: GO:0099106 {is_inferred="true"} ! ion channel regulator activity
+
+[Term]
 id: GO:0005247 ! voltage-gated chloride channel activity
 is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
 
@@ -8467,6 +8484,10 @@
 is_a: GO:0061097 {is_inferred="true"} ! regulation of protein tyrosine kinase activity
 
 [Term]
+id: GO:0007186 ! G-protein coupled receptor signaling pathway
+is_a: GO:0007165 {is_inferred="true"} ! signal transduction
+
+[Term]
 id: GO:0007194 ! negative regulation of adenylate cyclase activity
 is_a: GO:0031280 {is_inferred="true"} ! negative regulation of cyclase activity
 is_a: GO:0045761 {is_inferred="true"} ! regulation of adenylate cyclase activity
@@ -8799,6 +8820,7 @@
 [Term]
 id: GO:0008068 ! extracellular-glutamate-gated chloride channel activity
 is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
+is_a: GO:0099095 {is_inferred="true"} ! ligand-gated anion channel activity
 
 [Term]
 id: GO:0008069 ! dorsal/ventral axis specification, ovarian follicular epithelium
@@ -8850,6 +8872,11 @@
 is_a: GO:0005506 {is_inferred="true"} ! iron ion binding
 
 [Term]
+id: GO:0008200 ! ion channel inhibitor activity
+is_a: GO:0016248 {is_inferred="true"} ! channel inhibitor activity
+is_a: GO:0099106 {is_inferred="true"} ! ion channel regulator activity
+
+[Term]
 id: GO:0008201 ! heparin binding
 is_a: GO:0005539 {is_inferred="true"} ! glycosaminoglycan binding
 is_a: GO:0043168 {is_inferred="true"} ! anion binding
@@ -14296,6 +14323,10 @@
 is_a: GO:1902533 {is_inferred="true"} ! positive regulation of intracellular signal transduction
 
 [Term]
+id: GO:0014069 ! postsynaptic density
+is_a: GO:0099572 {is_inferred="true"} ! postsynaptic specialization
+
+[Term]
 id: GO:0014070 ! response to organic cyclic compound
 is_a: GO:0010033 {is_inferred="true"} ! response to organic substance
 
@@ -15108,10 +15139,25 @@
 is_a: GO:0015267 {is_inferred="true"} ! channel activity
 
 [Term]
+id: GO:0015276 ! ligand-gated ion channel activity
+is_a: GO:0005216 {is_inferred="true"} ! ion channel activity
+is_a: GO:0022834 {is_inferred="true"} ! ligand-gated channel activity
+
+[Term]
+id: GO:0015277 ! kainate selective glutamate receptor activity
+is_a: GO:0005267 {is_inferred="true"} ! potassium channel activity
+is_a: GO:0005272 {is_inferred="true"} ! sodium channel activity
+is_a: GO:0099094 {is_inferred="true"} ! ligand-gated cation channel activity
+
+[Term]
 id: GO:0015278 ! calcium-release channel activity
 is_a: GO:0099604 {is_inferred="true"} ! ligand-gated calcium channel activity
 
 [Term]
+id: GO:0015280 ! ligand-gated sodium channel activity
+is_a: GO:0099094 {is_inferred="true"} ! ligand-gated cation channel activity
+
+[Term]
 id: GO:0015284 ! fructose uniporter activity
 is_a: GO:0005353 {is_inferred="true"} ! fructose transmembrane transporter activity
 
@@ -15215,6 +15261,10 @@
 is_a: GO:0019829 {is_inferred="true"} ! cation-transporting ATPase activity
 
 [Term]
+id: GO:0015459 ! potassium channel regulator activity
+is_a: GO:0099106 {is_inferred="true"} ! ion channel regulator activity
+
+[Term]
 id: GO:0015483 ! long-chain fatty acid transporting porin activity
 is_a: GO:0005253 {is_inferred="true"} ! anion channel activity
 is_a: GO:0008028 {is_inferred="true"} ! monocarboxylic acid transmembrane transporter activity
@@ -17295,6 +17345,10 @@
 is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
 
 [Term]
+id: GO:0016557 ! peroxisome membrane biogenesis
+is_a: GO:0044091 {is_inferred="true"} ! membrane biogenesis
+
+[Term]
 id: GO:0016558 ! protein import into peroxisome matrix
 is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
@@ -17336,6 +17390,7 @@
 [Term]
 id: GO:0016934 ! extracellular-glycine-gated chloride channel activity
 is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
+is_a: GO:0099095 {is_inferred="true"} ! ligand-gated anion channel activity
 
 [Term]
 id: GO:0017015 ! regulation of transforming growth factor beta receptor signaling pathway
@@ -17343,6 +17398,11 @@
 is_a: GO:1903844 {is_inferred="true"} ! regulation of cellular response to transforming growth factor beta stimulus
 
 [Term]
+id: GO:0017020 ! myosin phosphatase regulator activity
+is_a: GO:0004721 {is_inferred="true"} ! phosphoprotein phosphatase activity
+is_a: GO:0030234 {is_inferred="true"} ! enzyme regulator activity
+
+[Term]
 id: GO:0017038 ! protein import
 is_a: GO:0015031 {is_inferred="true"} ! protein transport
 
@@ -17418,6 +17478,10 @@
 is_a: GO:0098798 {is_inferred="true"} ! mitochondrial protein complex
 
 [Term]
+id: GO:0017146 ! NMDA selective glutamate receptor complex
+is_a: GO:0034703 {is_inferred="true"} ! cation channel complex
+
+[Term]
 id: GO:0017148 ! negative regulation of translation
 is_a: GO:0006417 {is_inferred="true"} ! regulation of translation
 is_a: GO:0010629 {is_inferred="true"} ! negative regulation of gene expression
@@ -18058,6 +18122,7 @@
 [Term]
 id: GO:0019182 ! histamine-gated chloride channel activity
 is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
+is_a: GO:0099095 {is_inferred="true"} ! ligand-gated anion channel activity
 
 [Term]
 id: GO:0019183 ! histamine-gated chloride channel complex
@@ -18077,6 +18142,10 @@
 is_a: GO:1901505 {is_inferred="true"} ! carbohydrate derivative transporter activity
 
 [Term]
+id: GO:0019209 ! kinase activator activity
+is_a: GO:0019207 {is_inferred="true"} ! kinase regulator activity
+
+[Term]
 id: GO:0019216 ! regulation of lipid metabolic process
 is_a: GO:0080090 {is_inferred="true"} ! regulation of primary metabolic process
 
@@ -20409,10 +20478,12 @@
 id: GO:0022851 ! GABA-gated chloride ion channel activity
 is_a: GO:0016917 {is_inferred="true"} ! GABA receptor activity
 is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
+is_a: GO:0099095 {is_inferred="true"} ! ligand-gated anion channel activity
 
 [Term]
 id: GO:0022852 ! glycine-gated chloride ion channel activity
 is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
+is_a: GO:0099095 {is_inferred="true"} ! ligand-gated anion channel activity
 
 [Term]
 id: GO:0022858 ! alanine transmembrane transporter activity
@@ -20901,6 +20972,11 @@
 is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
 
 [Term]
+id: GO:0030295 ! protein kinase activator activity
+is_a: GO:0019209 {is_inferred="true"} ! kinase activator activity
+is_a: GO:0019887 {is_inferred="true"} ! protein kinase regulator activity
+
+[Term]
 id: GO:0030297 ! transmembrane receptor protein tyrosine kinase activator activity
 is_a: GO:0004871 {is_inferred="true"} ! signal transducer activity
 
@@ -21199,6 +21275,15 @@
 is_a: GO:0099602 {is_inferred="true"} ! neurotransmitter receptor regulator activity
 
 [Term]
+id: GO:0030549 ! acetylcholine receptor activator activity
+is_a: GO:0030546 {is_inferred="true"} ! receptor activator activity
+is_a: GO:0030548 {is_inferred="true"} ! acetylcholine receptor regulator activity
+
+[Term]
+id: GO:0030550 ! acetylcholine receptor inhibitor activity
+is_a: GO:0030548 {is_inferred="true"} ! acetylcholine receptor regulator activity
+
+[Term]
 id: GO:0030551 ! cyclic nucleotide binding
 is_a: GO:0000166 {is_inferred="true"} ! nucleotide binding
 
@@ -23893,6 +23978,10 @@
 is_a: GO:0006997 {is_inferred="true"} ! nucleus organization
 
 [Term]
+id: GO:0032127 ! dense core granule membrane
+is_a: GO:0030667 {is_inferred="true"} ! secretory granule membrane
+
+[Term]
 id: GO:0032130 ! medial membrane band assembly
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
 
@@ -26379,6 +26468,11 @@
 is_a: GO:0010257 {is_inferred="true"} ! NADH dehydrogenase complex assembly
 
 [Term]
+id: GO:0032983 ! kainate selective glutamate receptor complex
+is_a: GO:0034705 {is_inferred="true"} ! potassium channel complex
+is_a: GO:0034706 {is_inferred="true"} ! sodium channel complex
+
+[Term]
 id: GO:0032984 ! macromolecular complex disassembly
 is_a: GO:0022411 {is_inferred="true"} ! cellular component disassembly
 
@@ -29090,6 +29184,10 @@
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
+id: GO:0034414 ! tRNA 3'-trailer cleavage, endonucleolytic
+is_a: GO:1905267 {is_inferred="true"} ! endonucleolytic cleavage involved in tRNA processing
+
+[Term]
 id: GO:0034418 ! urate biosynthetic process
 is_a: GO:0046415 {is_inferred="true"} ! urate metabolic process
 is_a: GO:0072522 {is_inferred="true"} ! purine-containing compound biosynthetic process
@@ -30092,6 +30190,7 @@
 [Term]
 id: GO:0035424 ! MAPK import into nucleus involved in innate immune response
 is_a: GO:0000189 {is_inferred="true"} ! MAPK import into nucleus
+is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
 
 [Term]
 id: GO:0035428 ! hexose transmembrane transport
@@ -33364,6 +33463,10 @@
 is_a: GO:0045612 {is_inferred="true"} ! positive regulation of hemocyte differentiation
 
 [Term]
+id: GO:0042699 ! follicle-stimulating hormone signaling pathway
+is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
+
+[Term]
 id: GO:0042701 ! progesterone secretion
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 
@@ -35823,6 +35926,10 @@
 is_a: GO:0044088 {is_inferred="true"} ! regulation of vacuole organization
 
 [Term]
+id: GO:0044091 ! membrane biogenesis
+is_a: GO:0044085 {is_inferred="true"} ! cellular component biogenesis
+
+[Term]
 id: GO:0044092 ! negative regulation of molecular function
 is_a: GO:0065009 {is_inferred="true"} ! regulation of molecular function
 
@@ -37081,6 +37188,10 @@
 is_a: GO:0046204 {is_inferred="true"} ! nor-spermidine metabolic process
 
 [Term]
+id: GO:0045313 ! rhabdomere membrane biogenesis
+is_a: GO:0044091 {is_inferred="true"} ! membrane biogenesis
+
+[Term]
 id: GO:0045314 ! regulation of compound eye photoreceptor development
 is_a: GO:0042478 {is_inferred="true"} ! regulation of eye photoreceptor cell development
 
@@ -51987,6 +52098,10 @@
 is_a: GO:0048029 {is_inferred="true"} ! monosaccharide binding
 
 [Term]
+id: GO:0070062 ! extracellular exosome
+is_a: GO:1903561 {is_inferred="true"} ! extracellular vesicle
+
+[Term]
 id: GO:0070070 ! proton-transporting V-type ATPase complex assembly
 is_a: GO:0070071 {is_inferred="true"} ! proton-transporting two-sector ATPase complex assembly
 
@@ -56310,6 +56425,7 @@
 
 [Term]
 id: GO:0072101 ! specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway
+is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
 is_a: GO:0061216 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter involved in mesonephros development
 
 [Term]
@@ -56855,12 +56971,13 @@
 
 [Term]
 id: GO:0072411 ! signal transduction involved in meiotic cell cycle checkpoint
-is_a: GO:0022414 {is_inferred="true"} ! reproductive process
 is_a: GO:0072395 {is_inferred="true"} ! signal transduction involved in cell cycle checkpoint
+is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
 id: GO:0072413 ! signal transduction involved in mitotic cell cycle checkpoint
 is_a: GO:0072395 {is_inferred="true"} ! signal transduction involved in cell cycle checkpoint
+is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
 id: GO:0072415 ! detection of stimulus involved in spindle checkpoint
@@ -57240,8 +57357,8 @@
 
 [Term]
 id: GO:0072684 ! mitochondrial tRNA 3'-trailer cleavage, endonucleolytic
+is_a: GO:0000959 {is_inferred="true"} ! mitochondrial RNA metabolic process
 is_a: GO:0034414 {is_inferred="true"} ! tRNA 3'-trailer cleavage, endonucleolytic
-is_a: GO:1990180 {is_inferred="true"} ! mitochondrial tRNA 3'-end processing
 
 [Term]
 id: GO:0072691 ! initiation of premeiotic DNA replication
@@ -62068,6 +62185,7 @@
 
 [Term]
 id: GO:0098892 ! extrinsic component of postsynaptic specialization membrane
+is_a: GO:0044422 {is_inferred="true"} ! organelle part
 is_a: GO:0098890 {is_inferred="true"} ! extrinsic component of postsynaptic membrane
 
 [Term]
@@ -62102,8 +62220,10 @@
 
 [Term]
 id: GO:0098899 ! spine apparatus lumen
-is_a: GO:0034592 {is_inferred="true"} ! synaptic vesicle lumen
+is_a: GO:0044456 {is_inferred="true"} ! synapse part
 is_a: GO:0044463 {is_inferred="true"} ! cell projection part
+is_a: GO:0060205 {is_inferred="true"} ! cytoplasmic vesicle lumen
+is_a: GO:0097458 {is_inferred="true"} ! neuron part
 
 [Term]
 id: GO:0098900 ! regulation of action potential
@@ -62298,6 +62418,7 @@
 
 [Term]
 id: GO:0098948 ! intrinsic component of postsynaptic specialization membrane
+is_a: GO:0044422 {is_inferred="true"} ! organelle part
 is_a: GO:0098936 {is_inferred="true"} ! intrinsic component of postsynaptic membrane
 
 [Term]
@@ -62384,7 +62505,6 @@
 [Term]
 id: GO:0098966 ! perisynaptic extracellular matrix
 is_a: GO:0044420 {is_inferred="true"} ! extracellular matrix component
-is_a: GO:0044456 {is_inferred="true"} ! synapse part
 
 [Term]
 id: GO:0098967 ! exocytic insertion of neurotransmitter receptor to postsynaptic membrane
@@ -62776,6 +62896,84 @@
 is_a: GO:0032439 {is_inferred="true"} ! endosome localization
 
 [Term]
+id: GO:0099091 ! postsynaptic specialization, intracellular component
+is_a: GO:0044422 {is_inferred="true"} ! organelle part
+is_a: GO:0044456 {is_inferred="true"} ! synapse part
+is_a: GO:0044464 {is_inferred="true"} ! cell part
+
+[Term]
+id: GO:0099092 ! postsynaptic density, intracellular component
+is_a: GO:0044422 {is_inferred="true"} ! organelle part
+is_a: GO:0044456 {is_inferred="true"} ! synapse part
+is_a: GO:0044464 {is_inferred="true"} ! cell part
+
+[Term]
+id: GO:0099094 ! ligand-gated cation channel activity
+is_a: GO:0005261 {is_inferred="true"} ! cation channel activity
+is_a: GO:0015276 {is_inferred="true"} ! ligand-gated ion channel activity
+is_a: GO:0022890 {is_inferred="true"} ! inorganic cation transmembrane transporter activity
+
+[Term]
+id: GO:0099095 ! ligand-gated anion channel activity
+is_a: GO:0005253 {is_inferred="true"} ! anion channel activity
+is_a: GO:0015103 {is_inferred="true"} ! inorganic anion transmembrane transporter activity
+is_a: GO:0015276 {is_inferred="true"} ! ligand-gated ion channel activity
+
+[Term]
+id: GO:0099097 ! prospore membrane biogenesis
+is_a: GO:0044091 {is_inferred="true"} ! membrane biogenesis
+
+[Term]
+id: GO:0099099 ! G-protein gated ion channel activity
+is_a: GO:0005216 {is_inferred="true"} ! ion channel activity
+
+[Term]
+id: GO:0099100 ! G-protein gated cation channel activity
+is_a: GO:0005261 {is_inferred="true"} ! cation channel activity
+is_a: GO:0022890 {is_inferred="true"} ! inorganic cation transmembrane transporter activity
+is_a: GO:0099099 {is_inferred="true"} ! G-protein gated ion channel activity
+
+[Term]
+id: GO:0099101 ! G-protein gated potassium channel activity
+is_a: GO:0005267 {is_inferred="true"} ! potassium channel activity
+is_a: GO:0099100 {is_inferred="true"} ! G-protein gated cation channel activity
+
+[Term]
+id: GO:0099102 ! G-protein gated potassium channel activity involved in regulation of postsynaptic membrane potential
+is_a: GO:0099101 {is_inferred="true"} ! G-protein gated potassium channel activity
+
+[Term]
+id: GO:0099103 ! channel activator activity
+is_a: GO:0016247 {is_inferred="true"} ! channel regulator activity
+
+[Term]
+id: GO:0099104 ! potassium channel activator activity
+is_a: GO:0015459 {is_inferred="true"} ! potassium channel regulator activity
+is_a: GO:0099103 {is_inferred="true"} ! channel activator activity
+
+[Term]
+id: GO:0099105 ! ion channel modulating, G-protein coupled receptor signaling pathway
+is_a: GO:0007186 {is_inferred="true"} ! G-protein coupled receptor signaling pathway
+
+[Term]
+id: GO:0099106 ! ion channel regulator activity
+is_a: GO:0016247 {is_inferred="true"} ! channel regulator activity
+
+[Term]
+id: GO:0099107 ! ion channel regulator activity involved in G-protein coupled receptor signaling pathway
+is_a: GO:0004871 {is_inferred="true"} ! signal transducer activity
+is_a: GO:0099106 {is_inferred="true"} ! ion channel regulator activity
+
+[Term]
+id: GO:0099108 ! potassium channel activator activity involved in G-protein coupled receptor signaling pathway
+is_a: GO:0099104 {is_inferred="true"} ! potassium channel activator activity
+is_a: GO:0099107 {is_inferred="true"} ! ion channel regulator activity involved in G-protein coupled receptor signaling pathway
+
+[Term]
+id: GO:0099109 ! potassium channel activating, G-protein coupled receptor signaling pathway
+is_a: GO:0099105 {is_inferred="true"} ! ion channel modulating, G-protein coupled receptor signaling pathway
+
+[Term]
 id: GO:0099400 ! caveola neck
 is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
 
@@ -62945,6 +63143,10 @@
 is_a: GO:1905114 {is_inferred="true"} ! cell surface receptor signaling pathway involved in cell-cell signaling
 
 [Term]
+id: GO:0099566 ! regulation of postsynaptic cytosolic calcium ion concentration
+is_a: GO:0051480 {is_inferred="true"} ! regulation of cytosolic calcium ion concentration
+
+[Term]
 id: GO:0099567 ! calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration
 is_a: GO:0099510 {is_inferred="true"} ! calcium ion binding involved in regulation of cytosolic calcium ion concentration
 
@@ -62964,6 +63166,7 @@
 [Term]
 id: GO:0099572 ! postsynaptic specialization
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
+is_a: GO:0044464 {is_inferred="true"} ! cell part
 
 [Term]
 id: GO:0099574 ! regulation of protein catabolic process at synapse, modulating synaptic transmission
@@ -63009,6 +63212,10 @@
 is_a: GO:0098657 {is_inferred="true"} ! import into cell
 
 [Term]
+id: GO:0099588 ! positive regulation of postsynaptic cytosolic calcium concentration
+is_a: GO:0099566 {is_inferred="true"} ! regulation of postsynaptic cytosolic calcium ion concentration
+
+[Term]
 id: GO:0099601 ! regulation of neurotransmitter receptor activity
 is_a: GO:0010469 {is_inferred="true"} ! regulation of receptor activity
 
@@ -63020,7 +63227,7 @@
 id: GO:0099604 ! ligand-gated calcium channel activity
 is_a: GO:0004888 {is_inferred="true"} ! transmembrane signaling receptor activity
 is_a: GO:0005262 {is_inferred="true"} ! calcium channel activity
-is_a: GO:0015276 {is_inferred="true"} ! ligand-gated ion channel activity
+is_a: GO:0099094 {is_inferred="true"} ! ligand-gated cation channel activity
 
 [Term]
 id: GO:0099606 ! microtubule plus-end directed mitotic chromosome migration
@@ -63078,10 +63285,12 @@
 
 [Term]
 id: GO:0099633 ! protein localization to postsynaptic specialization membrane
+is_a: GO:0033365 {is_inferred="true"} ! protein localization to organelle
 is_a: GO:1903539 {is_inferred="true"} ! protein localization to postsynaptic membrane
 
 [Term]
 id: GO:0099634 ! postsynaptic specialization membrane
+is_a: GO:0044422 {is_inferred="true"} ! organelle part
 is_a: GO:0097060 {is_inferred="true"} ! synaptic membrane
 
 [Term]
@@ -75892,7 +76101,6 @@
 id: GO:1902402 ! signal transduction involved in mitotic DNA damage checkpoint
 is_a: GO:0072422 {is_inferred="true"} ! signal transduction involved in DNA damage checkpoint
 is_a: GO:1902403 {is_inferred="true"} ! signal transduction involved in mitotic DNA integrity checkpoint
-is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
 id: GO:1902403 ! signal transduction involved in mitotic DNA integrity checkpoint
@@ -75964,6 +76172,7 @@
 [Term]
 id: GO:1902420 ! signal transduction involved in Dma1-dependent checkpoint
 is_a: GO:0007165 {is_inferred="true"} ! signal transduction
+is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
 id: GO:1902421 ! hydrogen metabolic process
@@ -82721,6 +82930,7 @@
 [Term]
 id: GO:1903822 ! signal transduction involved in morphogenesis checkpoint
 is_a: GO:0007165 {is_inferred="true"} ! signal transduction
+is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
 id: GO:1903823 ! telomere single strand break repair
@@ -87426,17 +87636,17 @@
 
 [Term]
 id: GO:1904782 ! negative regulation of NMDA glutamate receptor activity
-is_a: GO:0032413 {is_inferred="true"} ! negative regulation of ion transmembrane transporter activity
 is_a: GO:1900450 {is_inferred="true"} ! negative regulation of glutamate receptor signaling pathway
 is_a: GO:2000272 {is_inferred="true"} ! negative regulation of receptor activity
 is_a: GO:2000310 {is_inferred="true"} ! regulation of N-methyl-D-aspartate selective glutamate receptor activity
+is_a: GO:2001258 {is_inferred="true"} ! negative regulation of cation channel activity
 
 [Term]
 id: GO:1904783 ! positive regulation of NMDA glutamate receptor activity
-is_a: GO:0032414 {is_inferred="true"} ! positive regulation of ion transmembrane transporter activity
 is_a: GO:1900451 {is_inferred="true"} ! positive regulation of glutamate receptor signaling pathway
 is_a: GO:2000273 {is_inferred="true"} ! positive regulation of receptor activity
 is_a: GO:2000310 {is_inferred="true"} ! regulation of N-methyl-D-aspartate selective glutamate receptor activity
+is_a: GO:2001259 {is_inferred="true"} ! positive regulation of cation channel activity
 
 [Term]
 id: GO:1904784 ! NLRP1 inflammasome complex assembly
@@ -94612,9 +94822,9 @@
 
 [Term]
 id: GO:2000310 ! regulation of N-methyl-D-aspartate selective glutamate receptor activity
-is_a: GO:0032412 {is_inferred="true"} ! regulation of ion transmembrane transporter activity
 is_a: GO:0099601 {is_inferred="true"} ! regulation of neurotransmitter receptor activity
 is_a: GO:1900449 {is_inferred="true"} ! regulation of glutamate receptor signaling pathway
+is_a: GO:2001257 {is_inferred="true"} ! regulation of cation channel activity
 
 [Term]
 id: GO:2000311 ! regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
@@ -94624,9 +94834,11 @@
 
 [Term]
 id: GO:2000312 ! regulation of kainate selective glutamate receptor activity
-is_a: GO:0032412 {is_inferred="true"} ! regulation of ion transmembrane transporter activity
 is_a: GO:0099601 {is_inferred="true"} ! regulation of neurotransmitter receptor activity
 is_a: GO:1900449 {is_inferred="true"} ! regulation of glutamate receptor signaling pathway
+is_a: GO:1901016 {is_inferred="true"} ! regulation of potassium ion transmembrane transporter activity
+is_a: GO:2000649 {is_inferred="true"} ! regulation of sodium ion transmembrane transporter activity
+is_a: GO:2001257 {is_inferred="true"} ! regulation of cation channel activity
 
 [Term]
 id: GO:2000313 ! regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
------------------------------------------------------------------------
r37108 | paola | 2016-11-21 03:46:44 -0800 (Mon, 21 Nov 2016) | 2 lines

GH Parentage of glycoprotein binding #12580 - closed - added link 'glycoprotein binding' is_a 'protein binding'

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37108)
+++ go_inferences.obo	(working copy)
@@ -2061,10 +2061,6 @@
 is_a: GO:0009967 {is_inferred="true"} ! positive regulation of signal transduction
 
 [Term]
-id: GO:0002162 ! dystroglycan binding
-is_a: GO:0005515 {is_inferred="true"} ! protein binding
-
-[Term]
 id: GO:0002169 ! 3-methylcrotonyl-CoA carboxylase complex, mitochondrial
 is_a: GO:0044429 {is_inferred="true"} ! mitochondrial part
 is_a: GO:1905202 {is_inferred="true"} ! methylcrotonoyl-CoA carboxylase complex
------------------------------------------------------------------------
r37085 | termgenie | 2016-11-18 14:17:39 -0800 (Fri, 18 Nov 2016) | 3 lines

TermGenie commit for user: hbye reviewed by tb

changes in entailments

------------------------------------------------------------------------
r37085 | termgenie | 2016-11-18 14:17:39 -0800 (Fri, 18 Nov 2016) | 3 lines

TermGenie commit for user: hbye reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37085)
+++ go_inferences.obo	(working copy)
@@ -22714,10 +22714,8 @@
 
 [Term]
 id: GO:0031383 ! regulation of mating projection assembly
-is_a: GO:0022604 {is_inferred="true"} ! regulation of cell morphogenesis
-is_a: GO:0031137 {is_inferred="true"} ! regulation of conjugation with cellular fusion
-is_a: GO:0048583 {is_inferred="true"} ! regulation of response to stimulus
 is_a: GO:0060491 {is_inferred="true"} ! regulation of cell projection assembly
+is_a: GO:1905708 {is_inferred="true"} ! regulation of cell morphogenesis involved in conjugation with cellular fusion
 
 [Term]
 id: GO:0031392 ! regulation of prostaglandin biosynthetic process
@@ -68986,6 +68984,7 @@
 is_a: GO:0010823 {is_inferred="true"} ! negative regulation of mitochondrion organization
 is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
 is_a: GO:1901028 {is_inferred="true"} ! regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
+is_a: GO:1905709 {is_inferred="true"} ! negative regulation of regulation of membrane permeability
 is_a: GO:2001234 {is_inferred="true"} ! negative regulation of apoptotic signaling pathway
 
 [Term]
@@ -68993,6 +68992,7 @@
 is_a: GO:0010822 {is_inferred="true"} ! positive regulation of mitochondrion organization
 is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
 is_a: GO:1901028 {is_inferred="true"} ! regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
+is_a: GO:1905710 {is_inferred="true"} ! positive regulation of regulation of membrane permeability
 is_a: GO:2001235 {is_inferred="true"} ! positive regulation of apoptotic signaling pathway
 
 [Term]
@@ -91976,6 +91976,22 @@
 is_a: GO:2001170 {is_inferred="true"} ! negative regulation of ATP biosynthetic process
 
 [Term]
+id: GO:1905708 ! regulation of cell morphogenesis involved in conjugation with cellular fusion
+is_a: GO:0022604 {is_inferred="true"} ! regulation of cell morphogenesis
+is_a: GO:0031137 {is_inferred="true"} ! regulation of conjugation with cellular fusion
+is_a: GO:0048583 {is_inferred="true"} ! regulation of response to stimulus
+
+[Term]
+id: GO:1905709 ! negative regulation of regulation of membrane permeability
+is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
+is_a: GO:0065008 {is_inferred="true"} ! regulation of biological quality
+
+[Term]
+id: GO:1905710 ! positive regulation of regulation of membrane permeability
+is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
+is_a: GO:0065008 {is_inferred="true"} ! regulation of biological quality
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37082 | tberardi | 2016-11-18 12:52:23 -0800 (Fri, 18 Nov 2016) | 1 line

GH2801 growth cone regions - closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37082)
+++ go_inferences.obo	(working copy)
@@ -25086,10 +25086,6 @@
 is_a: GO:0000139 {is_inferred="true"} ! Golgi membrane
 
 [Term]
-id: GO:0032584 ! growth cone membrane
-is_a: GO:0097458 {is_inferred="true"} ! neuron part
-
-[Term]
 id: GO:0032588 ! trans-Golgi network membrane
 is_a: GO:0000139 {is_inferred="true"} ! Golgi membrane
 
@@ -92811,11 +92807,6 @@
 is_a: GO:0031134 {is_inferred="true"} ! sister chromatid biorientation
 
 [Term]
-id: GO:1990761 ! growth cone lamellipodium
-is_a: GO:0044463 {is_inferred="true"} ! cell projection part
-is_a: GO:0097458 {is_inferred="true"} ! neuron part
-
-[Term]
 id: GO:1990771 ! clathrin-dependent extracellular exosome endocytosis
 is_a: GO:0051650 {is_inferred="true"} ! establishment of vesicle localization
 
------------------------------------------------------------------------
r37079 | dph | 2016-11-18 11:41:16 -0800 (Fri, 18 Nov 2016) | 2 lines

GH12794-closed

changes in entailments

------------------------------------------------------------------------
r37077 | dph | 2016-11-18 11:21:56 -0800 (Fri, 18 Nov 2016) | 2 lines

Added relationships between autophagy cellular components and processes and functions. GH12805-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37077)
+++ go_inferences.obo	(working copy)
@@ -28886,6 +28886,10 @@
 is_a: GO:1901606 {is_inferred="true"} ! alpha-amino acid catabolic process
 
 [Term]
+id: GO:0034274 ! Atg12-Atg5-Atg16 complex
+is_a: GO:1990234 {is_inferred="true"} ! transferase complex
+
+[Term]
 id: GO:0034275 ! kynurenic acid metabolic process
 is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
------------------------------------------------------------------------
r37063 | cjm | 2016-11-17 15:03:49 -0800 (Thu, 17 Nov 2016) | 1 line

null change, triggering new inferences, see https://github.com/geneontology/go-ontology/issues/12735

changes in entailments

------------------------------------------------------------------------
r37063 | cjm | 2016-11-17 15:03:49 -0800 (Thu, 17 Nov 2016) | 1 line

null change, triggering new inferences, see https://github.com/geneontology/go-ontology/issues/12735

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37063)
+++ go_inferences.obo	(working copy)
@@ -183,6 +183,7 @@
 [Term]
 id: GO:0000053 ! argininosuccinate metabolic process
 is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
+is_a: GO:0072350 {is_inferred="true"} ! tricarboxylic acid metabolic process
 is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
 
 [Term]
@@ -195,10 +196,12 @@
 
 [Term]
 id: GO:0000062 ! fatty-acyl-CoA binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:1901681 {is_inferred="true"} ! sulfur compound binding
 
 [Term]
 id: GO:0000064 ! L-ornithine transmembrane transporter activity
+is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
 is_a: GO:0015179 {is_inferred="true"} ! L-amino acid transmembrane transporter activity
 
 [Term]
@@ -230,23 +233,20 @@
 
 [Term]
 id: GO:0000096 ! sulfur amino acid metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
 is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
 
 [Term]
 id: GO:0000097 ! sulfur amino acid biosynthetic process
 is_a: GO:0000096 {is_inferred="true"} ! sulfur amino acid metabolic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
+is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 is_a: GO:0044272 {is_inferred="true"} ! sulfur compound biosynthetic process
-is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
 
 [Term]
 id: GO:0000098 ! sulfur amino acid catabolic process
 is_a: GO:0000096 {is_inferred="true"} ! sulfur amino acid metabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
+is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
 is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
-is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
 
 [Term]
 id: GO:0000099 ! sulfur amino acid transmembrane transporter activity
@@ -266,7 +266,10 @@
 [Term]
 id: GO:0000105 ! histidine biosynthetic process
 is_a: GO:0006547 {is_inferred="true"} ! histidine metabolic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
+is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
+is_a: GO:0019438 {is_inferred="true"} ! aromatic compound biosynthetic process
+is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
+is_a: GO:1901607 {is_inferred="true"} ! alpha-amino acid biosynthetic process
 
 [Term]
 id: GO:0000109 ! nucleotide-excision repair complex
@@ -560,6 +563,14 @@
 is_a: GO:0015216 {is_inferred="true"} ! purine nucleotide transmembrane transporter activity
 
 [Term]
+id: GO:0000296 ! spermine transport
+is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
+
+[Term]
+id: GO:0000297 ! spermine transmembrane transporter activity
+is_a: GO:0008519 {is_inferred="true"} ! ammonium transmembrane transporter activity
+
+[Term]
 id: GO:0000302 ! response to reactive oxygen species
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
@@ -942,15 +953,17 @@
 
 [Term]
 id: GO:0000820 ! regulation of glutamine family amino acid metabolic process
-is_a: GO:0031323 {is_inferred="true"} ! regulation of cellular metabolic process
-is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
+is_a: GO:0006521 {is_inferred="true"} ! regulation of cellular amino acid metabolic process
 
 [Term]
 id: GO:0000821 ! regulation of arginine metabolic process
 is_a: GO:0000820 {is_inferred="true"} ! regulation of glutamine family amino acid metabolic process
-is_a: GO:0006521 {is_inferred="true"} ! regulation of cellular amino acid metabolic process
 
 [Term]
+id: GO:0000822 ! inositol hexakisphosphate binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
+
+[Term]
 id: GO:0000835 ! ER ubiquitin ligase complex
 is_a: GO:0000153 {is_inferred="true"} ! cytoplasmic ubiquitin ligase complex
 is_a: GO:0044425 {is_inferred="true"} ! membrane part
@@ -1032,6 +1045,7 @@
 id: GO:0000954 ! methionine catabolic process to 3-methylthiopropanoate
 is_a: GO:0006633 {is_inferred="true"} ! fatty acid biosynthetic process
 is_a: GO:0009087 {is_inferred="true"} ! methionine catabolic process
+is_a: GO:0044272 {is_inferred="true"} ! sulfur compound biosynthetic process
 
 [Term]
 id: GO:0000957 ! mitochondrial RNA catabolic process
@@ -1204,7 +1218,12 @@
 is_a: GO:0098800 {is_inferred="true"} ! inner mitochondrial membrane protein complex
 
 [Term]
+id: GO:0001406 ! glycerophosphodiester transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+
+[Term]
 id: GO:0001407 ! glycerophosphodiester transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015748 {is_inferred="true"} ! organophosphate ester transport
 
 [Term]
@@ -1368,6 +1387,7 @@
 [Term]
 id: GO:0001692 ! histamine metabolic process
 is_a: GO:0052803 {is_inferred="true"} ! imidazole-containing compound metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 
 [Term]
 id: GO:0001694 ! histamine biosynthetic process
@@ -1847,7 +1867,6 @@
 
 [Term]
 id: GO:0002036 ! regulation of L-glutamate transport
-is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
 is_a: GO:0051955 {is_inferred="true"} ! regulation of amino acid transport
 
 [Term]
@@ -1854,13 +1873,11 @@
 id: GO:0002037 ! negative regulation of L-glutamate transport
 is_a: GO:0002036 {is_inferred="true"} ! regulation of L-glutamate transport
 is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
-is_a: GO:1903792 {is_inferred="true"} ! negative regulation of anion transport
 
 [Term]
 id: GO:0002038 ! positive regulation of L-glutamate transport
 is_a: GO:0002036 {is_inferred="true"} ! regulation of L-glutamate transport
 is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
-is_a: GO:1903793 {is_inferred="true"} ! positive regulation of anion transport
 
 [Term]
 id: GO:0002044 ! blood vessel endothelial cell migration involved in intussusceptive angiogenesis
@@ -1993,11 +2010,13 @@
 id: GO:0002134 ! UTP binding
 is_a: GO:0032551 {is_inferred="true"} ! pyrimidine ribonucleoside binding
 is_a: GO:0032557 {is_inferred="true"} ! pyrimidine ribonucleotide binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
 [Term]
 id: GO:0002135 ! CTP binding
 is_a: GO:0032551 {is_inferred="true"} ! pyrimidine ribonucleoside binding
 is_a: GO:0032557 {is_inferred="true"} ! pyrimidine ribonucleotide binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
 [Term]
 id: GO:0002138 ! retinoic acid biosynthetic process
@@ -2016,10 +2035,12 @@
 [Term]
 id: GO:0002148 ! hypochlorous acid metabolic process
 is_a: GO:0043436 {is_inferred="true"} ! oxoacid metabolic process
+is_a: GO:0072593 {is_inferred="true"} ! reactive oxygen species metabolic process
 
 [Term]
 id: GO:0002149 ! hypochlorous acid biosynthetic process
 is_a: GO:0002148 {is_inferred="true"} ! hypochlorous acid metabolic process
+is_a: GO:1903409 {is_inferred="true"} ! reactive oxygen species biosynthetic process
 
 [Term]
 id: GO:0002150 ! hypochlorous acid catabolic process
@@ -4879,23 +4900,34 @@
 
 [Term]
 id: GO:0005290 ! L-histidine transmembrane transporter activity
+is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
 is_a: GO:0015179 {is_inferred="true"} ! L-amino acid transmembrane transporter activity
 is_a: GO:1901474 {is_inferred="true"} ! azole transmembrane transporter activity
 
 [Term]
+id: GO:0005298 ! proline:sodium symporter activity
+is_a: GO:0015296 {is_inferred="true"} ! anion:cation symporter activity
+
+[Term]
 id: GO:0005302 ! L-tyrosine transmembrane transporter activity
+is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
 is_a: GO:0015173 {is_inferred="true"} ! aromatic amino acid transmembrane transporter activity
 is_a: GO:0015179 {is_inferred="true"} ! L-amino acid transmembrane transporter activity
 
 [Term]
 id: GO:0005304 ! L-valine transmembrane transporter activity
+is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
 is_a: GO:0015179 {is_inferred="true"} ! L-amino acid transmembrane transporter activity
 is_a: GO:0015658 {is_inferred="true"} ! branched-chain amino acid transmembrane transporter activity
 
 [Term]
+id: GO:0005308 ! creatine transmembrane transporter activity
+is_a: GO:0015171 {is_inferred="true"} ! amino acid transmembrane transporter activity
+
+[Term]
 id: GO:0005309 ! creatine:sodium symporter activity
-is_a: GO:0015081 {is_inferred="true"} ! sodium ion transmembrane transporter activity
-is_a: GO:0015293 {is_inferred="true"} ! symporter activity
+is_a: GO:0005343 {is_inferred="true"} ! organic acid:sodium symporter activity
+is_a: GO:0015296 {is_inferred="true"} ! anion:cation symporter activity
 
 [Term]
 id: GO:0005310 ! dicarboxylic acid transmembrane transporter activity
@@ -4903,7 +4935,8 @@
 
 [Term]
 id: GO:0005313 ! L-glutamate transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0005310 {is_inferred="true"} ! dicarboxylic acid transmembrane transporter activity
+is_a: GO:0015179 {is_inferred="true"} ! L-amino acid transmembrane transporter activity
 
 [Term]
 id: GO:0005315 ! inorganic phosphate transmembrane transporter activity
@@ -4920,9 +4953,14 @@
 [Term]
 id: GO:0005329 ! dopamine transmembrane transporter activity
 is_a: GO:0008504 {is_inferred="true"} ! monoamine transmembrane transporter activity
+is_a: GO:0008519 {is_inferred="true"} ! ammonium transmembrane transporter activity
 is_a: GO:1901618 {is_inferred="true"} ! organic hydroxy compound transmembrane transporter activity
 
 [Term]
+id: GO:0005332 ! gamma-aminobutyric acid:sodium symporter activity
+is_a: GO:0015296 {is_inferred="true"} ! anion:cation symporter activity
+
+[Term]
 id: GO:0005333 ! norepinephrine transmembrane transporter activity
 is_a: GO:0008504 {is_inferred="true"} ! monoamine transmembrane transporter activity
 is_a: GO:1901618 {is_inferred="true"} ! organic hydroxy compound transmembrane transporter activity
@@ -4942,6 +4980,7 @@
 
 [Term]
 id: GO:0005340 ! nucleotide-sulfate transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:0015215 {is_inferred="true"} ! nucleotide transmembrane transporter activity
 
 [Term]
@@ -4957,6 +4996,7 @@
 id: GO:0005347 ! ATP transmembrane transporter activity
 is_a: GO:0000295 {is_inferred="true"} ! adenine nucleotide transmembrane transporter activity
 is_a: GO:0005346 {is_inferred="true"} ! purine ribonucleotide transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:0015211 {is_inferred="true"} ! purine nucleoside transmembrane transporter activity
 
 [Term]
@@ -4985,11 +5025,17 @@
 
 [Term]
 id: GO:0005368 ! taurine transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0042959 {is_inferred="true"} ! alkanesulfonate transporter activity
 is_a: GO:1901682 {is_inferred="true"} ! sulfur compound transmembrane transporter activity
 
 [Term]
+id: GO:0005369 ! taurine:sodium symporter activity
+is_a: GO:0015296 {is_inferred="true"} ! anion:cation symporter activity
+
+[Term]
 id: GO:0005371 ! tricarboxylate secondary active transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0015142 {is_inferred="true"} ! tricarboxylic acid transmembrane transporter activity
 is_a: GO:0015291 {is_inferred="true"} ! secondary active transmembrane transporter activity
 
 [Term]
@@ -4997,10 +5043,26 @@
 is_a: GO:0015103 {is_inferred="true"} ! inorganic anion transmembrane transporter activity
 
 [Term]
+id: GO:0005456 ! CMP-N-acetylneuraminate transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+
+[Term]
+id: GO:0005460 ! UDP-glucose transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+
+[Term]
+id: GO:0005462 ! UDP-N-acetylglucosamine transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+
+[Term]
+id: GO:0005464 ! UDP-xylose transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+
+[Term]
 id: GO:0005471 ! ATP:ADP antiporter activity
 is_a: GO:0005347 {is_inferred="true"} ! ATP transmembrane transporter activity
 is_a: GO:0015217 {is_inferred="true"} ! ADP transmembrane transporter activity
-is_a: GO:0015297 {is_inferred="true"} ! antiporter activity
+is_a: GO:0015301 {is_inferred="true"} ! anion:anion antiporter activity
 
 [Term]
 id: GO:0005472 ! FAD carrier activity
@@ -5100,8 +5162,8 @@
 
 [Term]
 id: GO:0005542 ! folic acid binding
+is_a: GO:0031406 {is_inferred="true"} ! carboxylic acid binding
 is_a: GO:0033218 {is_inferred="true"} ! amide binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
 is_a: GO:0072341 {is_inferred="true"} ! modified amino acid binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
@@ -5109,6 +5171,7 @@
 [Term]
 id: GO:0005543 ! phospholipid binding
 is_a: GO:0008289 {is_inferred="true"} ! lipid binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
 [Term]
 id: GO:0005545 ! 1-phosphatidylinositol binding
@@ -5712,6 +5775,7 @@
 
 [Term]
 id: GO:0006011 ! UDP-glucose metabolic process
+is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
 is_a: GO:0009225 {is_inferred="true"} ! nucleotide-sugar metabolic process
 
 [Term]
@@ -5853,6 +5917,7 @@
 [Term]
 id: GO:0006047 ! UDP-N-acetylglucosamine metabolic process
 is_a: GO:0006040 {is_inferred="true"} ! amino sugar metabolic process
+is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
 is_a: GO:0009225 {is_inferred="true"} ! nucleotide-sugar metabolic process
 
 [Term]
@@ -5887,6 +5952,7 @@
 
 [Term]
 id: GO:0006054 ! N-acetylneuraminate metabolic process
+is_a: GO:0006040 {is_inferred="true"} ! amino sugar metabolic process
 is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 
 [Term]
@@ -5914,16 +5980,19 @@
 
 [Term]
 id: GO:0006063 ! uronic acid metabolic process
+is_a: GO:0005996 {is_inferred="true"} ! monosaccharide metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 
 [Term]
 id: GO:0006064 ! glucuronate catabolic process
 is_a: GO:0019585 {is_inferred="true"} ! glucuronate metabolic process
+is_a: GO:0046365 {is_inferred="true"} ! monosaccharide catabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 
 [Term]
 id: GO:0006065 ! UDP-glucuronate biosynthetic process
 is_a: GO:0009226 {is_inferred="true"} ! nucleotide-sugar biosynthetic process
+is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 is_a: GO:0046398 {is_inferred="true"} ! UDP-glucuronate metabolic process
 
 [Term]
@@ -6016,6 +6085,7 @@
 [Term]
 id: GO:0006089 ! lactate metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
 
 [Term]
 id: GO:0006090 ! pyruvate metabolic process
@@ -6046,7 +6116,7 @@
 
 [Term]
 id: GO:0006099 ! tricarboxylic acid cycle
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0006101 {is_inferred="true"} ! citrate metabolic process
 
 [Term]
 id: GO:0006101 ! citrate metabolic process
@@ -6117,9 +6187,9 @@
 
 [Term]
 id: GO:0006127 ! glycerophosphate shuttle
+is_a: GO:0006072 {is_inferred="true"} ! glycerol-3-phosphate metabolic process
 is_a: GO:0006116 {is_inferred="true"} ! NADH oxidation
 is_a: GO:0042180 {is_inferred="true"} ! cellular ketone metabolic process
-is_a: GO:1901135 {is_inferred="true"} ! carbohydrate derivative metabolic process
 
 [Term]
 id: GO:0006139 ! nucleobase-containing compound metabolic process
@@ -6479,8 +6549,9 @@
 
 [Term]
 id: GO:0006234 ! TTP biosynthetic process
+is_a: GO:0009209 {is_inferred="true"} ! pyrimidine ribonucleoside triphosphate biosynthetic process
+is_a: GO:0009220 {is_inferred="true"} ! pyrimidine ribonucleotide biosynthetic process
 is_a: GO:0046046 {is_inferred="true"} ! TTP metabolic process
-is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
 
 [Term]
 id: GO:0006235 ! dTTP biosynthetic process
@@ -6813,65 +6884,56 @@
 is_a: GO:0080090 {is_inferred="true"} ! regulation of primary metabolic process
 
 [Term]
-id: GO:0006522 ! alanine metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
-
-[Term]
 id: GO:0006523 ! alanine biosynthetic process
 is_a: GO:0006522 {is_inferred="true"} ! alanine metabolic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 
 [Term]
 id: GO:0006524 ! alanine catabolic process
 is_a: GO:0006522 {is_inferred="true"} ! alanine metabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
 
 [Term]
-id: GO:0006525 ! arginine metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
-
-[Term]
 id: GO:0006526 ! arginine biosynthetic process
 is_a: GO:0006525 {is_inferred="true"} ! arginine metabolic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 
 [Term]
 id: GO:0006527 ! arginine catabolic process
 is_a: GO:0006525 {is_inferred="true"} ! arginine metabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
 
 [Term]
 id: GO:0006528 ! asparagine metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0043603 {is_inferred="true"} ! cellular amide metabolic process
 
 [Term]
 id: GO:0006529 ! asparagine biosynthetic process
 is_a: GO:0006528 {is_inferred="true"} ! asparagine metabolic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
+is_a: GO:0043604 {is_inferred="true"} ! amide biosynthetic process
+is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 
 [Term]
 id: GO:0006530 ! asparagine catabolic process
 is_a: GO:0006528 {is_inferred="true"} ! asparagine metabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
+is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 
 [Term]
 id: GO:0006531 ! aspartate metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
 is_a: GO:0043648 {is_inferred="true"} ! dicarboxylic acid metabolic process
 
 [Term]
 id: GO:0006532 ! aspartate biosynthetic process
 is_a: GO:0006531 {is_inferred="true"} ! aspartate metabolic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 is_a: GO:0043650 {is_inferred="true"} ! dicarboxylic acid biosynthetic process
 
 [Term]
 id: GO:0006533 ! aspartate catabolic process
 is_a: GO:0006531 {is_inferred="true"} ! aspartate metabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
 is_a: GO:0043649 {is_inferred="true"} ! dicarboxylic acid catabolic process
 
 [Term]
+id: GO:0006534 ! cysteine metabolic process
+is_a: GO:0000096 {is_inferred="true"} ! sulfur amino acid metabolic process
+
+[Term]
 id: GO:0006535 ! cysteine biosynthetic process from serine
 is_a: GO:0006563 {is_inferred="true"} ! L-serine metabolic process
 is_a: GO:0019344 {is_inferred="true"} ! cysteine biosynthetic process
@@ -6900,41 +6962,31 @@
 is_a: GO:0006538 {is_inferred="true"} ! glutamate catabolic process
 
 [Term]
-id: GO:0006541 ! glutamine metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
-
-[Term]
 id: GO:0006542 ! glutamine biosynthetic process
 is_a: GO:0006541 {is_inferred="true"} ! glutamine metabolic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 
 [Term]
 id: GO:0006543 ! glutamine catabolic process
 is_a: GO:0006541 {is_inferred="true"} ! glutamine metabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
 
 [Term]
-id: GO:0006544 ! glycine metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
-
-[Term]
 id: GO:0006545 ! glycine biosynthetic process
 is_a: GO:0006544 {is_inferred="true"} ! glycine metabolic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 
 [Term]
 id: GO:0006546 ! glycine catabolic process
 is_a: GO:0006544 {is_inferred="true"} ! glycine metabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
 
 [Term]
 id: GO:0006547 ! histidine metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
+is_a: GO:0052803 {is_inferred="true"} ! imidazole-containing compound metabolic process
+is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
 
 [Term]
 id: GO:0006548 ! histidine catabolic process
 is_a: GO:0006547 {is_inferred="true"} ! histidine metabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
+is_a: GO:0052805 {is_inferred="true"} ! imidazole-containing compound catabolic process
+is_a: GO:1901606 {is_inferred="true"} ! alpha-amino acid catabolic process
 
 [Term]
 id: GO:0006549 ! isoleucine metabolic process
@@ -6949,30 +7001,28 @@
 
 [Term]
 id: GO:0006551 ! leucine metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
+is_a: GO:0009081 {is_inferred="true"} ! branched-chain amino acid metabolic process
+is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
 
 [Term]
 id: GO:0006552 ! leucine catabolic process
 is_a: GO:0006551 {is_inferred="true"} ! leucine metabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
+is_a: GO:0009083 {is_inferred="true"} ! branched-chain amino acid catabolic process
+is_a: GO:1901606 {is_inferred="true"} ! alpha-amino acid catabolic process
 
 [Term]
-id: GO:0006553 ! lysine metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
-
-[Term]
 id: GO:0006554 ! lysine catabolic process
 is_a: GO:0006553 {is_inferred="true"} ! lysine metabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
 
 [Term]
 id: GO:0006555 ! methionine metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
+is_a: GO:0000096 {is_inferred="true"} ! sulfur amino acid metabolic process
 
 [Term]
 id: GO:0006556 ! S-adenosylmethionine biosynthetic process
 is_a: GO:0044272 {is_inferred="true"} ! sulfur compound biosynthetic process
 is_a: GO:0046500 {is_inferred="true"} ! S-adenosylmethionine metabolic process
+is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
 
 [Term]
 id: GO:0006557 ! S-adenosylmethioninamine biosynthetic process
@@ -6982,49 +7032,43 @@
 
 [Term]
 id: GO:0006558 ! L-phenylalanine metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
+is_a: GO:0009072 {is_inferred="true"} ! aromatic amino acid family metabolic process
+is_a: GO:1902221 {is_inferred="true"} ! erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process
 
 [Term]
 id: GO:0006559 ! L-phenylalanine catabolic process
 is_a: GO:0006558 {is_inferred="true"} ! L-phenylalanine metabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
+is_a: GO:0009074 {is_inferred="true"} ! aromatic amino acid family catabolic process
+is_a: GO:1902222 {is_inferred="true"} ! erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process
 
 [Term]
 id: GO:0006560 ! proline metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
+is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
+is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
 
 [Term]
 id: GO:0006561 ! proline biosynthetic process
 is_a: GO:0006560 {is_inferred="true"} ! proline metabolic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
+is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
+is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
 
 [Term]
 id: GO:0006562 ! proline catabolic process
 is_a: GO:0006560 {is_inferred="true"} ! proline metabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
+is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
+is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
 
 [Term]
-id: GO:0006563 ! L-serine metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
-
-[Term]
 id: GO:0006564 ! L-serine biosynthetic process
 is_a: GO:0006563 {is_inferred="true"} ! L-serine metabolic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 
 [Term]
 id: GO:0006565 ! L-serine catabolic process
 is_a: GO:0006563 {is_inferred="true"} ! L-serine metabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
 
 [Term]
-id: GO:0006566 ! threonine metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
-
-[Term]
 id: GO:0006567 ! threonine catabolic process
 is_a: GO:0006566 {is_inferred="true"} ! threonine metabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
 
 [Term]
 id: GO:0006568 ! tryptophan metabolic process
@@ -7057,12 +7101,14 @@
 
 [Term]
 id: GO:0006573 ! valine metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
+is_a: GO:0009081 {is_inferred="true"} ! branched-chain amino acid metabolic process
+is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
 
 [Term]
 id: GO:0006574 ! valine catabolic process
 is_a: GO:0006573 {is_inferred="true"} ! valine metabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
+is_a: GO:0009083 {is_inferred="true"} ! branched-chain amino acid catabolic process
+is_a: GO:1901606 {is_inferred="true"} ! alpha-amino acid catabolic process
 
 [Term]
 id: GO:0006575 ! cellular modified amino acid metabolic process
@@ -7086,6 +7132,7 @@
 id: GO:0006580 ! ethanolamine metabolic process
 is_a: GO:0034308 {is_inferred="true"} ! primary alcohol metabolic process
 is_a: GO:0042439 {is_inferred="true"} ! ethanolamine-containing compound metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 is_a: GO:1901160 {is_inferred="true"} ! primary amino compound metabolic process
 
 [Term]
@@ -7133,17 +7180,17 @@
 
 [Term]
 id: GO:0006591 ! ornithine metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
+is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
 
 [Term]
 id: GO:0006592 ! ornithine biosynthetic process
 is_a: GO:0006591 {is_inferred="true"} ! ornithine metabolic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
+is_a: GO:1901607 {is_inferred="true"} ! alpha-amino acid biosynthetic process
 
 [Term]
 id: GO:0006593 ! ornithine catabolic process
 is_a: GO:0006591 {is_inferred="true"} ! ornithine metabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
+is_a: GO:1901606 {is_inferred="true"} ! alpha-amino acid catabolic process
 
 [Term]
 id: GO:0006596 ! polyamine biosynthetic process
@@ -7165,12 +7212,14 @@
 
 [Term]
 id: GO:0006600 ! creatine metabolic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
+is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
+is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
 
 [Term]
 id: GO:0006601 ! creatine biosynthetic process
 is_a: GO:0006600 {is_inferred="true"} ! creatine metabolic process
 is_a: GO:0042398 {is_inferred="true"} ! cellular modified amino acid biosynthetic process
+is_a: GO:1901607 {is_inferred="true"} ! alpha-amino acid biosynthetic process
 
 [Term]
 id: GO:0006602 ! creatinine catabolic process
@@ -7256,6 +7305,7 @@
 
 [Term]
 id: GO:0006637 ! acyl-CoA metabolic process
+is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
 is_a: GO:0035383 {is_inferred="true"} ! thioester metabolic process
 
 [Term]
@@ -7298,12 +7348,12 @@
 
 [Term]
 id: GO:0006653 ! 1,2-diacyl-sn-glycero-3-phosphocholine metabolic process
-is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
+is_a: GO:0046470 {is_inferred="true"} ! phosphatidylcholine metabolic process
 
 [Term]
 id: GO:0006654 ! phosphatidic acid biosynthetic process
 is_a: GO:0046473 {is_inferred="true"} ! phosphatidic acid metabolic process
-is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
+is_a: GO:0046474 {is_inferred="true"} ! glycerophospholipid biosynthetic process
 
 [Term]
 id: GO:0006655 ! phosphatidylglycerol biosynthetic process
@@ -7487,6 +7537,7 @@
 [Term]
 id: GO:0006690 ! icosanoid metabolic process
 is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
+is_a: GO:1901568 {is_inferred="true"} ! fatty acid derivative metabolic process
 
 [Term]
 id: GO:0006691 ! leukotriene metabolic process
@@ -7533,6 +7584,7 @@
 is_a: GO:0006694 {is_inferred="true"} ! steroid biosynthetic process
 is_a: GO:0008206 {is_inferred="true"} ! bile acid metabolic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
+is_a: GO:1901617 {is_inferred="true"} ! organic hydroxy compound biosynthetic process
 
 [Term]
 id: GO:0006700 ! C21-steroid hormone biosynthetic process
@@ -7746,16 +7798,24 @@
 [Term]
 id: GO:0006760 ! folic acid-containing compound metabolic process
 is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
+is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 is_a: GO:0042558 {is_inferred="true"} ! pteridine-containing compound metabolic process
+is_a: GO:0043603 {is_inferred="true"} ! cellular amide metabolic process
 
 [Term]
 id: GO:0006761 ! dihydrofolate biosynthetic process
 is_a: GO:0009396 {is_inferred="true"} ! folic acid-containing compound biosynthetic process
+is_a: GO:0043650 {is_inferred="true"} ! dicarboxylic acid biosynthetic process
 is_a: GO:0046452 {is_inferred="true"} ! dihydrofolate metabolic process
 
 [Term]
 id: GO:0006768 ! biotin metabolic process
+is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0043603 {is_inferred="true"} ! cellular amide metabolic process
+is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
+is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
+is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
 
 [Term]
 id: GO:0006769 ! nicotinamide metabolic process
@@ -7797,6 +7857,7 @@
 
 [Term]
 id: GO:0006780 ! uroporphyrinogen III biosynthetic process
+is_a: GO:0006779 {is_inferred="true"} ! porphyrin-containing compound biosynthetic process
 is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 is_a: GO:0046502 {is_inferred="true"} ! uroporphyrinogen III metabolic process
 
@@ -7852,11 +7913,13 @@
 id: GO:0006798 ! polyphosphate catabolic process
 is_a: GO:0006797 {is_inferred="true"} ! polyphosphate metabolic process
 is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
+is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
 
 [Term]
 id: GO:0006799 ! polyphosphate biosynthetic process
 is_a: GO:0006797 {is_inferred="true"} ! polyphosphate metabolic process
 is_a: GO:0044711 {is_inferred="true"} ! single-organism biosynthetic process
+is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
 
 [Term]
 id: GO:0006801 ! superoxide metabolic process
@@ -7932,6 +7995,7 @@
 
 [Term]
 id: GO:0006837 ! serotonin transport
+is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 is_a: GO:0015844 {is_inferred="true"} ! monoamine transport
 is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
 
@@ -7967,7 +8031,7 @@
 
 [Term]
 id: GO:0006853 ! carnitine shuttle
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:1902001 {is_inferred="true"} ! fatty acid transmembrane transport
 
 [Term]
 id: GO:0006857 ! oligopeptide transport
@@ -8002,16 +8066,18 @@
 
 [Term]
 id: GO:0006865 ! amino acid transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
 is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
 id: GO:0006867 ! asparagine transport
-is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
+is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
+is_a: GO:0042886 {is_inferred="true"} ! amide transport
 
 [Term]
 id: GO:0006868 ! glutamine transport
-is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
 
 [Term]
 id: GO:0006869 ! lipid transport
@@ -8769,7 +8835,7 @@
 
 [Term]
 id: GO:0008153 ! para-aminobenzoic acid biosynthetic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
+is_a: GO:0009073 {is_inferred="true"} ! aromatic amino acid family biosynthetic process
 is_a: GO:0046482 {is_inferred="true"} ! para-aminobenzoic acid metabolic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 
@@ -8790,6 +8856,7 @@
 [Term]
 id: GO:0008201 ! heparin binding
 is_a: GO:0005539 {is_inferred="true"} ! glycosaminoglycan binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:1901681 {is_inferred="true"} ! sulfur compound binding
 
 [Term]
@@ -8818,6 +8885,7 @@
 id: GO:0008206 ! bile acid metabolic process
 is_a: GO:0008202 {is_inferred="true"} ! steroid metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
 
 [Term]
 id: GO:0008207 ! C21-steroid hormone metabolic process
@@ -8839,6 +8907,14 @@
 is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
 
 [Term]
+id: GO:0008215 ! spermine metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
+
+[Term]
+id: GO:0008216 ! spermidine metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
+
+[Term]
 id: GO:0008247 ! 1-alkyl-2-acetylglycerophosphocholine esterase complex
 is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
 
@@ -9005,6 +9081,10 @@
 is_a: GO:0015291 {is_inferred="true"} ! secondary active transmembrane transporter activity
 
 [Term]
+id: GO:0008508 ! bile acid:sodium symporter activity
+is_a: GO:0015296 {is_inferred="true"} ! anion:cation symporter activity
+
+[Term]
 id: GO:0008509 ! anion transmembrane transporter activity
 is_a: GO:0015075 {is_inferred="true"} ! ion transmembrane transporter activity
 
@@ -9022,10 +9102,11 @@
 
 [Term]
 id: GO:0008520 ! L-ascorbate:sodium symporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
-is_a: GO:0015081 {is_inferred="true"} ! sodium ion transmembrane transporter activity
+is_a: GO:0005343 {is_inferred="true"} ! organic acid:sodium symporter activity
+is_a: GO:0015145 {is_inferred="true"} ! monosaccharide transmembrane transporter activity
 is_a: GO:0015229 {is_inferred="true"} ! L-ascorbic acid transporter activity
 is_a: GO:0015296 {is_inferred="true"} ! anion:cation symporter activity
+is_a: GO:0046943 {is_inferred="true"} ! carboxylic acid transmembrane transporter activity
 is_a: GO:0090482 {is_inferred="true"} ! vitamin transmembrane transporter activity
 
 [Term]
@@ -9157,7 +9238,7 @@
 [Term]
 id: GO:0008658 ! penicillin binding
 is_a: GO:0033218 {is_inferred="true"} ! amide binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
+is_a: GO:0033293 {is_inferred="true"} ! monocarboxylic acid binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
 is_a: GO:1901681 {is_inferred="true"} ! sulfur compound binding
@@ -9232,26 +9313,23 @@
 
 [Term]
 id: GO:0009072 ! aromatic amino acid family metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
 is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
 is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
 
 [Term]
 id: GO:0009073 ! aromatic amino acid family biosynthetic process
+is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 is_a: GO:0009072 {is_inferred="true"} ! aromatic amino acid family metabolic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0019438 {is_inferred="true"} ! aromatic compound biosynthetic process
 is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
-is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
 
 [Term]
 id: GO:0009074 ! aromatic amino acid family catabolic process
+is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
 is_a: GO:0009072 {is_inferred="true"} ! aromatic amino acid family metabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
 is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
 is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
-is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
 
 [Term]
 id: GO:0009078 ! pyruvate family amino acid metabolic process
@@ -9267,20 +9345,17 @@
 
 [Term]
 id: GO:0009081 ! branched-chain amino acid metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
+is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
 
 [Term]
 id: GO:0009082 ! branched-chain amino acid biosynthetic process
+is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 is_a: GO:0009081 {is_inferred="true"} ! branched-chain amino acid metabolic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
-is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
 
 [Term]
 id: GO:0009083 ! branched-chain amino acid catabolic process
+is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
 is_a: GO:0009081 {is_inferred="true"} ! branched-chain amino acid metabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
-is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
 
 [Term]
 id: GO:0009084 ! glutamine family amino acid biosynthetic process
@@ -9289,22 +9364,20 @@
 [Term]
 id: GO:0009085 ! lysine biosynthetic process
 is_a: GO:0006553 {is_inferred="true"} ! lysine metabolic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 
 [Term]
 id: GO:0009086 ! methionine biosynthetic process
+is_a: GO:0000097 {is_inferred="true"} ! sulfur amino acid biosynthetic process
 is_a: GO:0006555 {is_inferred="true"} ! methionine metabolic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 
 [Term]
 id: GO:0009087 ! methionine catabolic process
+is_a: GO:0000098 {is_inferred="true"} ! sulfur amino acid catabolic process
 is_a: GO:0006555 {is_inferred="true"} ! methionine metabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
 
 [Term]
 id: GO:0009088 ! threonine biosynthetic process
 is_a: GO:0006566 {is_inferred="true"} ! threonine metabolic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 
 [Term]
 id: GO:0009089 ! lysine biosynthetic process via diaminopimelate
@@ -9312,26 +9385,21 @@
 
 [Term]
 id: GO:0009090 ! homoserine biosynthetic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 is_a: GO:0009092 {is_inferred="true"} ! homoserine metabolic process
 
 [Term]
 id: GO:0009091 ! homoserine catabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
 is_a: GO:0009092 {is_inferred="true"} ! homoserine metabolic process
 
 [Term]
-id: GO:0009092 ! homoserine metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
-
-[Term]
 id: GO:0009093 ! cysteine catabolic process
+is_a: GO:0000098 {is_inferred="true"} ! sulfur amino acid catabolic process
 is_a: GO:0006534 {is_inferred="true"} ! cysteine metabolic process
 
 [Term]
 id: GO:0009094 ! L-phenylalanine biosynthetic process
 is_a: GO:0006558 {is_inferred="true"} ! L-phenylalanine metabolic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
+is_a: GO:1902223 {is_inferred="true"} ! erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process
 
 [Term]
 id: GO:0009097 ! isoleucine biosynthetic process
@@ -9342,12 +9410,14 @@
 [Term]
 id: GO:0009098 ! leucine biosynthetic process
 is_a: GO:0006551 {is_inferred="true"} ! leucine metabolic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
+is_a: GO:0009082 {is_inferred="true"} ! branched-chain amino acid biosynthetic process
+is_a: GO:1901607 {is_inferred="true"} ! alpha-amino acid biosynthetic process
 
 [Term]
 id: GO:0009099 ! valine biosynthetic process
 is_a: GO:0006573 {is_inferred="true"} ! valine metabolic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
+is_a: GO:0009082 {is_inferred="true"} ! branched-chain amino acid biosynthetic process
+is_a: GO:1901607 {is_inferred="true"} ! alpha-amino acid biosynthetic process
 
 [Term]
 id: GO:0009100 ! glycoprotein metabolic process
@@ -9361,7 +9431,12 @@
 [Term]
 id: GO:0009102 ! biotin biosynthetic process
 is_a: GO:0006768 {is_inferred="true"} ! biotin metabolic process
+is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
+is_a: GO:0043604 {is_inferred="true"} ! amide biosynthetic process
+is_a: GO:0044272 {is_inferred="true"} ! sulfur compound biosynthetic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
+is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
+is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
 
 [Term]
 id: GO:0009103 ! lipopolysaccharide biosynthetic process
@@ -9378,11 +9453,17 @@
 [Term]
 id: GO:0009106 ! lipoate metabolic process
 is_a: GO:0006631 {is_inferred="true"} ! fatty acid metabolic process
+is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
+is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
+is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
 
 [Term]
 id: GO:0009107 ! lipoate biosynthetic process
 is_a: GO:0006633 {is_inferred="true"} ! fatty acid biosynthetic process
 is_a: GO:0009106 {is_inferred="true"} ! lipoate metabolic process
+is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
+is_a: GO:0044272 {is_inferred="true"} ! sulfur compound biosynthetic process
+is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
 
 [Term]
 id: GO:0009110 ! vitamin biosynthetic process
@@ -9988,6 +10069,7 @@
 id: GO:0009229 ! thiamine diphosphate biosynthetic process
 is_a: GO:0019438 {is_inferred="true"} ! aromatic compound biosynthetic process
 is_a: GO:0042357 {is_inferred="true"} ! thiamine diphosphate metabolic process
+is_a: GO:0044272 {is_inferred="true"} ! sulfur compound biosynthetic process
 is_a: GO:0072528 {is_inferred="true"} ! pyrimidine-containing compound biosynthetic process
 is_a: GO:0090407 {is_inferred="true"} ! organophosphate biosynthetic process
 
@@ -10089,11 +10171,13 @@
 
 [Term]
 id: GO:0009256 ! 10-formyltetrahydrofolate metabolic process
+is_a: GO:0043648 {is_inferred="true"} ! dicarboxylic acid metabolic process
 is_a: GO:0046653 {is_inferred="true"} ! tetrahydrofolate metabolic process
 
 [Term]
 id: GO:0009257 ! 10-formyltetrahydrofolate biosynthetic process
 is_a: GO:0009256 {is_inferred="true"} ! 10-formyltetrahydrofolate metabolic process
+is_a: GO:0043650 {is_inferred="true"} ! dicarboxylic acid biosynthetic process
 is_a: GO:0046654 {is_inferred="true"} ! tetrahydrofolate biosynthetic process
 
 [Term]
@@ -10100,6 +10184,7 @@
 id: GO:0009258 ! 10-formyltetrahydrofolate catabolic process
 is_a: GO:0009256 {is_inferred="true"} ! 10-formyltetrahydrofolate metabolic process
 is_a: GO:0009397 {is_inferred="true"} ! folic acid-containing compound catabolic process
+is_a: GO:0043649 {is_inferred="true"} ! dicarboxylic acid catabolic process
 
 [Term]
 id: GO:0009259 ! ribonucleotide metabolic process
@@ -10332,7 +10417,11 @@
 
 [Term]
 id: GO:0009374 ! biotin binding
+is_a: GO:0033218 {is_inferred="true"} ! amide binding
 is_a: GO:0033293 {is_inferred="true"} ! monocarboxylic acid binding
+is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
+is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
+is_a: GO:1901681 {is_inferred="true"} ! sulfur compound binding
 
 [Term]
 id: GO:0009375 ! ferredoxin hydrogenase complex
@@ -10374,6 +10463,8 @@
 is_a: GO:0006760 {is_inferred="true"} ! folic acid-containing compound metabolic process
 is_a: GO:0042398 {is_inferred="true"} ! cellular modified amino acid biosynthetic process
 is_a: GO:0042559 {is_inferred="true"} ! pteridine-containing compound biosynthetic process
+is_a: GO:0043604 {is_inferred="true"} ! amide biosynthetic process
+is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 
 [Term]
 id: GO:0009397 ! folic acid-containing compound catabolic process
@@ -10380,6 +10471,7 @@
 is_a: GO:0006760 {is_inferred="true"} ! folic acid-containing compound metabolic process
 is_a: GO:0042219 {is_inferred="true"} ! cellular modified amino acid catabolic process
 is_a: GO:0042560 {is_inferred="true"} ! pteridine-containing compound catabolic process
+is_a: GO:0046395 {is_inferred="true"} ! carboxylic acid catabolic process
 
 [Term]
 id: GO:0009398 ! FMN biosynthetic process
@@ -10414,6 +10506,7 @@
 
 [Term]
 id: GO:0009436 ! glyoxylate catabolic process
+is_a: GO:0046185 {is_inferred="true"} ! aldehyde catabolic process
 is_a: GO:0046487 {is_inferred="true"} ! glyoxylate metabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 
@@ -10420,6 +10513,7 @@
 [Term]
 id: GO:0009437 ! carnitine metabolic process
 is_a: GO:0006577 {is_inferred="true"} ! amino-acid betaine metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 
 [Term]
 id: GO:0009438 ! methylglyoxal metabolic process
@@ -10439,8 +10533,13 @@
 [Term]
 id: GO:0009441 ! glycolate metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0034308 {is_inferred="true"} ! primary alcohol metabolic process
 
 [Term]
+id: GO:0009445 ! putrescine metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
+
+[Term]
 id: GO:0009446 ! putrescine biosynthetic process
 is_a: GO:0009445 {is_inferred="true"} ! putrescine metabolic process
 
@@ -10451,16 +10550,19 @@
 [Term]
 id: GO:0009448 ! gamma-aminobutyric acid metabolic process
 is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 
 [Term]
 id: GO:0009449 ! gamma-aminobutyric acid biosynthetic process
 is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 is_a: GO:0009448 {is_inferred="true"} ! gamma-aminobutyric acid metabolic process
+is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 
 [Term]
 id: GO:0009450 ! gamma-aminobutyric acid catabolic process
 is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
 is_a: GO:0009448 {is_inferred="true"} ! gamma-aminobutyric acid metabolic process
+is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 
 [Term]
 id: GO:0009503 ! thylakoid light-harvesting complex
@@ -10594,32 +10696,40 @@
 
 [Term]
 id: GO:0009683 ! indoleacetic acid metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 is_a: GO:0042430 {is_inferred="true"} ! indole-containing compound metabolic process
 
 [Term]
 id: GO:0009684 ! indoleacetic acid biosynthetic process
+is_a: GO:0009683 {is_inferred="true"} ! indoleacetic acid metabolic process
+is_a: GO:0042435 {is_inferred="true"} ! indole-containing compound biosynthetic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 
 [Term]
 id: GO:0009685 ! gibberellin metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
 is_a: GO:0016101 {is_inferred="true"} ! diterpenoid metabolic process
+is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 
 [Term]
 id: GO:0009686 ! gibberellin biosynthetic process
 is_a: GO:0009685 {is_inferred="true"} ! gibberellin metabolic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0016102 {is_inferred="true"} ! diterpenoid biosynthetic process
+is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 
 [Term]
 id: GO:0009687 ! abscisic acid metabolic process
+is_a: GO:0006714 {is_inferred="true"} ! sesquiterpenoid metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0043288 {is_inferred="true"} ! apocarotenoid metabolic process
+is_a: GO:1902644 {is_inferred="true"} ! tertiary alcohol metabolic process
 
 [Term]
 id: GO:0009688 ! abscisic acid biosynthetic process
 is_a: GO:0009687 {is_inferred="true"} ! abscisic acid metabolic process
+is_a: GO:0016106 {is_inferred="true"} ! sesquiterpenoid biosynthetic process
+is_a: GO:0043289 {is_inferred="true"} ! apocarotenoid biosynthetic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
+is_a: GO:1902645 {is_inferred="true"} ! tertiary alcohol biosynthetic process
 
 [Term]
 id: GO:0009692 ! ethylene metabolic process
@@ -10641,11 +10751,14 @@
 
 [Term]
 id: GO:0009696 ! salicylic acid metabolic process
+is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 
 [Term]
 id: GO:0009697 ! salicylic acid biosynthetic process
 is_a: GO:0009696 {is_inferred="true"} ! salicylic acid metabolic process
+is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 
 [Term]
@@ -10782,7 +10895,7 @@
 
 [Term]
 id: GO:0009759 ! indole glucosinolate biosynthetic process
-is_a: GO:0016144 {is_inferred="true"} ! S-glycoside biosynthetic process
+is_a: GO:0019761 {is_inferred="true"} ! glucosinolate biosynthetic process
 is_a: GO:0042343 {is_inferred="true"} ! indole glucosinolate metabolic process
 is_a: GO:0042435 {is_inferred="true"} ! indole-containing compound biosynthetic process
 
@@ -10851,6 +10964,7 @@
 id: GO:0009803 ! cinnamic acid metabolic process
 is_a: GO:0009698 {is_inferred="true"} ! phenylpropanoid metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 
 [Term]
 id: GO:0009804 ! coumarin metabolic process
@@ -11214,7 +11328,7 @@
 [Term]
 id: GO:0010013 ! N-1-naphthylphthalamic acid binding
 is_a: GO:0033218 {is_inferred="true"} ! amide binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
+is_a: GO:0033293 {is_inferred="true"} ! monocarboxylic acid binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 
 [Term]
@@ -11256,6 +11370,7 @@
 
 [Term]
 id: GO:0010034 ! response to acetate
+is_a: GO:0001101 {is_inferred="true"} ! response to acid chemical
 is_a: GO:0010033 {is_inferred="true"} ! response to organic substance
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
@@ -11467,12 +11582,18 @@
 
 [Term]
 id: GO:0010115 ! regulation of abscisic acid biosynthetic process
+is_a: GO:0019747 {is_inferred="true"} ! regulation of isoprenoid metabolic process
 is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
+is_a: GO:0046890 {is_inferred="true"} ! regulation of lipid biosynthetic process
+is_a: GO:1902930 {is_inferred="true"} ! regulation of alcohol biosynthetic process
 
 [Term]
 id: GO:0010116 ! positive regulation of abscisic acid biosynthetic process
 is_a: GO:0010115 {is_inferred="true"} ! regulation of abscisic acid biosynthetic process
 is_a: GO:0031328 {is_inferred="true"} ! positive regulation of cellular biosynthetic process
+is_a: GO:0045828 {is_inferred="true"} ! positive regulation of isoprenoid metabolic process
+is_a: GO:0046889 {is_inferred="true"} ! positive regulation of lipid biosynthetic process
+is_a: GO:1902932 {is_inferred="true"} ! positive regulation of alcohol biosynthetic process
 
 [Term]
 id: GO:0010119 ! regulation of stomatal movement
@@ -11503,7 +11624,10 @@
 
 [Term]
 id: GO:0010124 ! phenylacetate catabolic process
+is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
+is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
+is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
 
 [Term]
 id: GO:0010125 ! mycothiol biosynthetic process
@@ -11545,13 +11669,7 @@
 
 [Term]
 id: GO:0010144 ! pyridoxal phosphate biosynthetic process from pyridoxamine
-is_a: GO:0006796 {is_inferred="true"} ! phosphate-containing compound metabolic process
-is_a: GO:0019438 {is_inferred="true"} ! aromatic compound biosynthetic process
 is_a: GO:0042818 {is_inferred="true"} ! pyridoxamine metabolic process
-is_a: GO:0046184 {is_inferred="true"} ! aldehyde biosynthetic process
-is_a: GO:0072525 {is_inferred="true"} ! pyridine-containing compound biosynthetic process
-is_a: GO:0090407 {is_inferred="true"} ! organophosphate biosynthetic process
-is_a: GO:1901617 {is_inferred="true"} ! organic hydroxy compound biosynthetic process
 
 [Term]
 id: GO:0010146 ! fructan biosynthetic process
@@ -11567,6 +11685,7 @@
 
 [Term]
 id: GO:0010157 ! response to chlorate
+is_a: GO:0001101 {is_inferred="true"} ! response to acid chemical
 is_a: GO:0010035 {is_inferred="true"} ! response to inorganic substance
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
@@ -11577,6 +11696,7 @@
 
 [Term]
 id: GO:0010167 ! response to nitrate
+is_a: GO:0001101 {is_inferred="true"} ! response to acid chemical
 is_a: GO:0010035 {is_inferred="true"} ! response to inorganic substance
 is_a: GO:1901698 {is_inferred="true"} ! response to nitrogen compound
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
@@ -11591,6 +11711,8 @@
 
 [Term]
 id: GO:0010175 ! sphingosine transmembrane transporter activity
+is_a: GO:0008519 {is_inferred="true"} ! ammonium transmembrane transporter activity
+is_a: GO:0015101 {is_inferred="true"} ! organic cation transmembrane transporter activity
 is_a: GO:0015166 {is_inferred="true"} ! polyol transmembrane transporter activity
 is_a: GO:0046624 {is_inferred="true"} ! sphingolipid transporter activity
 
@@ -11597,6 +11719,7 @@
 [Term]
 id: GO:0010181 ! FMN binding
 is_a: GO:0032553 {is_inferred="true"} ! ribonucleotide binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
 [Term]
 id: GO:0010183 ! pollen tube guidance
@@ -11698,6 +11821,7 @@
 [Term]
 id: GO:0010250 ! S-methylmethionine biosynthetic process
 is_a: GO:0033477 {is_inferred="true"} ! S-methylmethionine metabolic process
+is_a: GO:0042398 {is_inferred="true"} ! cellular modified amino acid biosynthetic process
 is_a: GO:0044272 {is_inferred="true"} ! sulfur compound biosynthetic process
 
 [Term]
@@ -11706,8 +11830,8 @@
 
 [Term]
 id: GO:0010253 ! UDP-rhamnose biosynthetic process
+is_a: GO:0009226 {is_inferred="true"} ! nucleotide-sugar biosynthetic process
 is_a: GO:0033478 {is_inferred="true"} ! UDP-rhamnose metabolic process
-is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
 
 [Term]
 id: GO:0010254 ! nectary development
@@ -11766,8 +11890,9 @@
 id: GO:0010292 ! GTP:GDP antiporter activity
 is_a: GO:0001409 {is_inferred="true"} ! guanine nucleotide transmembrane transporter activity
 is_a: GO:0005346 {is_inferred="true"} ! purine ribonucleotide transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:0015211 {is_inferred="true"} ! purine nucleoside transmembrane transporter activity
-is_a: GO:0015297 {is_inferred="true"} ! antiporter activity
+is_a: GO:0015301 {is_inferred="true"} ! anion:anion antiporter activity
 
 [Term]
 id: GO:0010297 ! heteropolysaccharide binding
@@ -11824,10 +11949,11 @@
 [Term]
 id: GO:0010331 ! gibberellin binding
 is_a: GO:0019840 {is_inferred="true"} ! isoprenoid binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
+is_a: GO:0031406 {is_inferred="true"} ! carboxylic acid binding
 
 [Term]
 id: GO:0010336 ! gibberellic acid homeostasis
+is_a: GO:0055081 {is_inferred="true"} ! anion homeostasis
 is_a: GO:0055088 {is_inferred="true"} ! lipid homeostasis
 
 [Term]
@@ -11930,6 +12056,8 @@
 
 [Term]
 id: GO:0010379 ! phaseic acid biosynthetic process
+is_a: GO:0016106 {is_inferred="true"} ! sesquiterpenoid biosynthetic process
+is_a: GO:0043289 {is_inferred="true"} ! apocarotenoid biosynthetic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 
 [Term]
@@ -11998,7 +12126,9 @@
 
 [Term]
 id: GO:0010427 ! abscisic acid binding
+is_a: GO:0019840 {is_inferred="true"} ! isoprenoid binding
 is_a: GO:0033293 {is_inferred="true"} ! monocarboxylic acid binding
+is_a: GO:0043178 {is_inferred="true"} ! alcohol binding
 
 [Term]
 id: GO:0010431 ! seed maturation
@@ -12017,6 +12147,7 @@
 id: GO:0010439 ! regulation of glucosinolate biosynthetic process
 is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
 is_a: GO:0042762 {is_inferred="true"} ! regulation of sulfur metabolic process
+is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
 is_a: GO:1900376 {is_inferred="true"} ! regulation of secondary metabolite biosynthetic process
 
 [Term]
@@ -12962,7 +13093,6 @@
 
 [Term]
 id: GO:0010746 ! regulation of plasma membrane long-chain fatty acid transport
-is_a: GO:0032890 {is_inferred="true"} ! regulation of organic acid transport
 is_a: GO:1903959 {is_inferred="true"} ! regulation of anion transmembrane transport
 is_a: GO:2000191 {is_inferred="true"} ! regulation of fatty acid transport
 
@@ -12969,7 +13099,6 @@
 [Term]
 id: GO:0010747 ! positive regulation of plasma membrane long-chain fatty acid transport
 is_a: GO:0010746 {is_inferred="true"} ! regulation of plasma membrane long-chain fatty acid transport
-is_a: GO:0032892 {is_inferred="true"} ! positive regulation of organic acid transport
 is_a: GO:1903961 {is_inferred="true"} ! positive regulation of anion transmembrane transport
 is_a: GO:2000193 {is_inferred="true"} ! positive regulation of fatty acid transport
 
@@ -12976,7 +13105,6 @@
 [Term]
 id: GO:0010748 ! negative regulation of plasma membrane long-chain fatty acid transport
 is_a: GO:0010746 {is_inferred="true"} ! regulation of plasma membrane long-chain fatty acid transport
-is_a: GO:0032891 {is_inferred="true"} ! negative regulation of organic acid transport
 is_a: GO:1903960 {is_inferred="true"} ! negative regulation of anion transmembrane transport
 is_a: GO:2000192 {is_inferred="true"} ! negative regulation of fatty acid transport
 
@@ -13555,9 +13683,11 @@
 [Term]
 id: GO:0010904 ! regulation of UDP-glucose catabolic process
 is_a: GO:0019219 {is_inferred="true"} ! regulation of nucleobase-containing compound metabolic process
+is_a: GO:0051174 {is_inferred="true"} ! regulation of phosphorus metabolic process
 
 [Term]
 id: GO:0010905 ! negative regulation of UDP-glucose catabolic process
+is_a: GO:0010563 {is_inferred="true"} ! negative regulation of phosphorus metabolic process
 is_a: GO:0010904 {is_inferred="true"} ! regulation of UDP-glucose catabolic process
 is_a: GO:0031330 {is_inferred="true"} ! negative regulation of cellular catabolic process
 is_a: GO:0045934 {is_inferred="true"} ! negative regulation of nucleobase-containing compound metabolic process
@@ -14063,23 +14193,25 @@
 [Term]
 id: GO:0014047 ! glutamate secretion
 is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
+is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
+is_a: GO:0046717 {is_inferred="true"} ! acid secretion
 
 [Term]
 id: GO:0014048 ! regulation of glutamate secretion
-is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
+is_a: GO:0051955 {is_inferred="true"} ! regulation of amino acid transport
 is_a: GO:1903530 {is_inferred="true"} ! regulation of secretion by cell
 
 [Term]
 id: GO:0014049 ! positive regulation of glutamate secretion
 is_a: GO:0014048 {is_inferred="true"} ! regulation of glutamate secretion
+is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
 is_a: GO:1903532 {is_inferred="true"} ! positive regulation of secretion by cell
-is_a: GO:1903793 {is_inferred="true"} ! positive regulation of anion transport
 
 [Term]
 id: GO:0014050 ! negative regulation of glutamate secretion
 is_a: GO:0014048 {is_inferred="true"} ! regulation of glutamate secretion
+is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
 is_a: GO:1903531 {is_inferred="true"} ! negative regulation of secretion by cell
-is_a: GO:1903792 {is_inferred="true"} ! negative regulation of anion transport
 
 [Term]
 id: GO:0014051 ! gamma-aminobutyric acid secretion
@@ -14087,20 +14219,20 @@
 
 [Term]
 id: GO:0014052 ! regulation of gamma-aminobutyric acid secretion
-is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
 is_a: GO:0051046 {is_inferred="true"} ! regulation of secretion
+is_a: GO:0051955 {is_inferred="true"} ! regulation of amino acid transport
 
 [Term]
 id: GO:0014053 ! negative regulation of gamma-aminobutyric acid secretion
 is_a: GO:0014052 {is_inferred="true"} ! regulation of gamma-aminobutyric acid secretion
 is_a: GO:0051048 {is_inferred="true"} ! negative regulation of secretion
-is_a: GO:1903792 {is_inferred="true"} ! negative regulation of anion transport
+is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
 
 [Term]
 id: GO:0014054 ! positive regulation of gamma-aminobutyric acid secretion
 is_a: GO:0014052 {is_inferred="true"} ! regulation of gamma-aminobutyric acid secretion
 is_a: GO:0051047 {is_inferred="true"} ! positive regulation of secretion
-is_a: GO:1903793 {is_inferred="true"} ! positive regulation of anion transport
+is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
 
 [Term]
 id: GO:0014056 ! regulation of acetylcholine secretion, neurotransmission
@@ -14124,6 +14256,7 @@
 
 [Term]
 id: GO:0014059 ! regulation of dopamine secretion
+is_a: GO:0043269 {is_inferred="true"} ! regulation of ion transport
 is_a: GO:0050433 {is_inferred="true"} ! regulation of catecholamine secretion
 
 [Term]
@@ -14137,16 +14270,19 @@
 
 [Term]
 id: GO:0014062 ! regulation of serotonin secretion
+is_a: GO:0043269 {is_inferred="true"} ! regulation of ion transport
 is_a: GO:1903530 {is_inferred="true"} ! regulation of secretion by cell
 
 [Term]
 id: GO:0014063 ! negative regulation of serotonin secretion
 is_a: GO:0014062 {is_inferred="true"} ! regulation of serotonin secretion
+is_a: GO:0043271 {is_inferred="true"} ! negative regulation of ion transport
 is_a: GO:1903531 {is_inferred="true"} ! negative regulation of secretion by cell
 
 [Term]
 id: GO:0014064 ! positive regulation of serotonin secretion
 is_a: GO:0014062 {is_inferred="true"} ! regulation of serotonin secretion
+is_a: GO:0043270 {is_inferred="true"} ! positive regulation of ion transport
 is_a: GO:1903532 {is_inferred="true"} ! positive regulation of secretion by cell
 
 [Term]
@@ -14518,6 +14654,7 @@
 is_a: GO:0030166 {is_inferred="true"} ! proteoglycan biosynthetic process
 is_a: GO:0030201 {is_inferred="true"} ! heparan sulfate proteoglycan metabolic process
 is_a: GO:0044272 {is_inferred="true"} ! sulfur compound biosynthetic process
+is_a: GO:0044711 {is_inferred="true"} ! single-organism biosynthetic process
 
 [Term]
 id: GO:0015031 ! protein transport
@@ -14547,7 +14684,9 @@
 
 [Term]
 id: GO:0015120 ! phosphoglycerate transmembrane transporter activity
+is_a: GO:0015605 {is_inferred="true"} ! organophosphate ester transmembrane transporter activity
 is_a: GO:0042879 {is_inferred="true"} ! aldonate transmembrane transporter activity
+is_a: GO:1901505 {is_inferred="true"} ! carbohydrate derivative transporter activity
 
 [Term]
 id: GO:0015121 ! phosphoenolpyruvate:phosphate antiporter activity
@@ -14555,11 +14694,11 @@
 
 [Term]
 id: GO:0015123 ! acetate transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0008028 {is_inferred="true"} ! monocarboxylic acid transmembrane transporter activity
 
 [Term]
 id: GO:0015124 ! allantoate transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0008028 {is_inferred="true"} ! monocarboxylic acid transmembrane transporter activity
 is_a: GO:0042887 {is_inferred="true"} ! amide transmembrane transporter activity
 
 [Term]
@@ -14578,11 +14717,13 @@
 
 [Term]
 id: GO:0015129 ! lactate transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0008028 {is_inferred="true"} ! monocarboxylic acid transmembrane transporter activity
+is_a: GO:1901618 {is_inferred="true"} ! organic hydroxy compound transmembrane transporter activity
 
 [Term]
 id: GO:0015130 ! mevalonate transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0008028 {is_inferred="true"} ! monocarboxylic acid transmembrane transporter activity
+is_a: GO:1901618 {is_inferred="true"} ! organic hydroxy compound transmembrane transporter activity
 
 [Term]
 id: GO:0015131 ! oxaloacetate transmembrane transporter activity
@@ -14599,16 +14740,16 @@
 
 [Term]
 id: GO:0015135 ! glucuronate transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0015134 {is_inferred="true"} ! hexuronate transmembrane transporter activity
 
 [Term]
 id: GO:0015136 ! sialic acid transmembrane transporter activity
-is_a: GO:0022857 {is_inferred="true"} ! transmembrane transporter activity
+is_a: GO:0046943 {is_inferred="true"} ! carboxylic acid transmembrane transporter activity
 is_a: GO:1901505 {is_inferred="true"} ! carbohydrate derivative transporter activity
 
 [Term]
 id: GO:0015137 ! citrate transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0015142 {is_inferred="true"} ! tricarboxylic acid transmembrane transporter activity
 
 [Term]
 id: GO:0015138 ! fumarate transmembrane transporter activity
@@ -14616,7 +14757,7 @@
 
 [Term]
 id: GO:0015139 ! alpha-ketoglutarate transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0005310 {is_inferred="true"} ! dicarboxylic acid transmembrane transporter activity
 
 [Term]
 id: GO:0015142 ! tricarboxylic acid transmembrane transporter activity
@@ -14686,7 +14827,7 @@
 
 [Term]
 id: GO:0015164 ! glucuronoside transmembrane transporter activity
-is_a: GO:0022857 {is_inferred="true"} ! transmembrane transporter activity
+is_a: GO:0046943 {is_inferred="true"} ! carboxylic acid transmembrane transporter activity
 is_a: GO:1901505 {is_inferred="true"} ! carbohydrate derivative transporter activity
 
 [Term]
@@ -14701,6 +14842,7 @@
 
 [Term]
 id: GO:0015169 ! glycerol-3-phosphate transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:0015605 {is_inferred="true"} ! organophosphate ester transmembrane transporter activity
 is_a: GO:1901505 {is_inferred="true"} ! carbohydrate derivative transporter activity
 
@@ -14726,12 +14868,19 @@
 is_a: GO:0022858 {is_inferred="true"} ! alanine transmembrane transporter activity
 
 [Term]
+id: GO:0015181 ! arginine transmembrane transporter activity
+is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
+
+[Term]
 id: GO:0015182 ! L-asparagine transmembrane transporter activity
+is_a: GO:0008028 {is_inferred="true"} ! monocarboxylic acid transmembrane transporter activity
+is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
 is_a: GO:0015179 {is_inferred="true"} ! L-amino acid transmembrane transporter activity
 is_a: GO:0042887 {is_inferred="true"} ! amide transmembrane transporter activity
 
 [Term]
 id: GO:0015183 ! L-aspartate transmembrane transporter activity
+is_a: GO:0015179 {is_inferred="true"} ! L-amino acid transmembrane transporter activity
 is_a: GO:0015556 {is_inferred="true"} ! C4-dicarboxylate transmembrane transporter activity
 
 [Term]
@@ -14746,23 +14895,28 @@
 
 [Term]
 id: GO:0015186 ! L-glutamine transmembrane transporter activity
+is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
 is_a: GO:0015179 {is_inferred="true"} ! L-amino acid transmembrane transporter activity
 
 [Term]
 id: GO:0015187 ! glycine transmembrane transporter activity
+is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
 is_a: GO:0015179 {is_inferred="true"} ! L-amino acid transmembrane transporter activity
 
 [Term]
 id: GO:0015188 ! L-isoleucine transmembrane transporter activity
+is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
 is_a: GO:0015179 {is_inferred="true"} ! L-amino acid transmembrane transporter activity
 is_a: GO:0015658 {is_inferred="true"} ! branched-chain amino acid transmembrane transporter activity
 
 [Term]
 id: GO:0015189 ! L-lysine transmembrane transporter activity
+is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
 is_a: GO:0015179 {is_inferred="true"} ! L-amino acid transmembrane transporter activity
 
 [Term]
 id: GO:0015190 ! L-leucine transmembrane transporter activity
+is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
 is_a: GO:0015179 {is_inferred="true"} ! L-amino acid transmembrane transporter activity
 is_a: GO:0015658 {is_inferred="true"} ! branched-chain amino acid transmembrane transporter activity
 
@@ -14773,11 +14927,13 @@
 
 [Term]
 id: GO:0015192 ! L-phenylalanine transmembrane transporter activity
+is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
 is_a: GO:0015173 {is_inferred="true"} ! aromatic amino acid transmembrane transporter activity
 is_a: GO:0015179 {is_inferred="true"} ! L-amino acid transmembrane transporter activity
 
 [Term]
 id: GO:0015193 ! L-proline transmembrane transporter activity
+is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
 is_a: GO:0015179 {is_inferred="true"} ! L-amino acid transmembrane transporter activity
 
 [Term]
@@ -14788,10 +14944,12 @@
 
 [Term]
 id: GO:0015195 ! L-threonine transmembrane transporter activity
+is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
 is_a: GO:0015179 {is_inferred="true"} ! L-amino acid transmembrane transporter activity
 
 [Term]
 id: GO:0015196 ! L-tryptophan transmembrane transporter activity
+is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
 is_a: GO:0015173 {is_inferred="true"} ! aromatic amino acid transmembrane transporter activity
 is_a: GO:0015179 {is_inferred="true"} ! L-amino acid transmembrane transporter activity
 
@@ -14801,6 +14959,7 @@
 
 [Term]
 id: GO:0015199 ! amino-acid betaine transmembrane transporter activity
+is_a: GO:0008519 {is_inferred="true"} ! ammonium transmembrane transporter activity
 is_a: GO:0015651 {is_inferred="true"} ! quaternary ammonium group transmembrane transporter activity
 is_a: GO:0072349 {is_inferred="true"} ! modified amino acid transmembrane transporter activity
 
@@ -14807,6 +14966,7 @@
 [Term]
 id: GO:0015200 ! methylammonium transmembrane transporter activity
 is_a: GO:0008519 {is_inferred="true"} ! ammonium transmembrane transporter activity
+is_a: GO:0015101 {is_inferred="true"} ! organic cation transmembrane transporter activity
 
 [Term]
 id: GO:0015204 ! urea transmembrane transporter activity
@@ -14856,6 +15016,7 @@
 id: GO:0015217 ! ADP transmembrane transporter activity
 is_a: GO:0000295 {is_inferred="true"} ! adenine nucleotide transmembrane transporter activity
 is_a: GO:0005346 {is_inferred="true"} ! purine ribonucleotide transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:0015211 {is_inferred="true"} ! purine nucleoside transmembrane transporter activity
 
 [Term]
@@ -14880,6 +15041,7 @@
 [Term]
 id: GO:0015222 ! serotonin transmembrane transporter activity
 is_a: GO:0008504 {is_inferred="true"} ! monoamine transmembrane transporter activity
+is_a: GO:0008519 {is_inferred="true"} ! ammonium transmembrane transporter activity
 is_a: GO:1901618 {is_inferred="true"} ! organic hydroxy compound transmembrane transporter activity
 
 [Term]
@@ -14888,14 +15050,21 @@
 
 [Term]
 id: GO:0015228 ! coenzyme A transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:0071077 {is_inferred="true"} ! adenosine 3',5'-bisphosphate transmembrane transporter activity
 
 [Term]
+id: GO:0015229 ! L-ascorbic acid transporter activity
+is_a: GO:1901476 {is_inferred="true"} ! carbohydrate transporter activity
+
+[Term]
 id: GO:0015230 ! FAD transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:0015215 {is_inferred="true"} ! nucleotide transmembrane transporter activity
 
 [Term]
 id: GO:0015233 ! pantothenate transmembrane transporter activity
+is_a: GO:0008028 {is_inferred="true"} ! monocarboxylic acid transmembrane transporter activity
 is_a: GO:0042887 {is_inferred="true"} ! amide transmembrane transporter activity
 
 [Term]
@@ -14960,10 +15129,11 @@
 
 [Term]
 id: GO:0015306 ! sialate:cation symporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0015136 {is_inferred="true"} ! sialic acid transmembrane transporter activity
 
 [Term]
 id: GO:0015308 ! amiloride:proton antiporter activity
+is_a: GO:0015101 {is_inferred="true"} ! organic cation transmembrane transporter activity
 is_a: GO:0042887 {is_inferred="true"} ! amide transmembrane transporter activity
 
 [Term]
@@ -14986,11 +15156,12 @@
 
 [Term]
 id: GO:0015325 ! acetyl-CoA:CoA antiporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:1901682 {is_inferred="true"} ! sulfur compound transmembrane transporter activity
 
 [Term]
 id: GO:0015327 ! cystine:glutamate antiporter activity
-is_a: GO:0015297 {is_inferred="true"} ! antiporter activity
+is_a: GO:0015301 {is_inferred="true"} ! anion:anion antiporter activity
 is_a: GO:0015328 {is_inferred="true"} ! cystine secondary active transmembrane transporter activity
 
 [Term]
@@ -15012,6 +15183,10 @@
 is_a: GO:1901618 {is_inferred="true"} ! organic hydroxy compound transmembrane transporter activity
 
 [Term]
+id: GO:0015375 ! glycine:sodium symporter activity
+is_a: GO:0015296 {is_inferred="true"} ! anion:cation symporter activity
+
+[Term]
 id: GO:0015388 ! potassium uptake transmembrane transporter activity
 is_a: GO:0015563 {is_inferred="true"} ! uptake transmembrane transporter activity
 
@@ -15045,6 +15220,7 @@
 
 [Term]
 id: GO:0015483 ! long-chain fatty acid transporting porin activity
+is_a: GO:0005253 {is_inferred="true"} ! anion channel activity
 is_a: GO:0008028 {is_inferred="true"} ! monocarboxylic acid transmembrane transporter activity
 
 [Term]
@@ -15053,22 +15229,31 @@
 is_a: GO:0043178 {is_inferred="true"} ! alcohol binding
 
 [Term]
+id: GO:0015489 ! putrescine transmembrane transporter activity
+is_a: GO:0008519 {is_inferred="true"} ! ammonium transmembrane transporter activity
+is_a: GO:0015101 {is_inferred="true"} ! organic cation transmembrane transporter activity
+
+[Term]
+id: GO:0015490 ! cadaverine transmembrane transporter activity
+is_a: GO:0008519 {is_inferred="true"} ! ammonium transmembrane transporter activity
+is_a: GO:0015101 {is_inferred="true"} ! organic cation transmembrane transporter activity
+
+[Term]
 id: GO:0015491 ! cation:cation antiporter activity
 is_a: GO:0099516 {is_inferred="true"} ! ion antiporter activity
 
 [Term]
 id: GO:0015496 ! putrescine:ornithine antiporter activity
-is_a: GO:0015297 {is_inferred="true"} ! antiporter activity
+is_a: GO:0015491 {is_inferred="true"} ! cation:cation antiporter activity
 
 [Term]
 id: GO:0015498 ! pantothenate:sodium symporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
-is_a: GO:0015081 {is_inferred="true"} ! sodium ion transmembrane transporter activity
+is_a: GO:0005343 {is_inferred="true"} ! organic acid:sodium symporter activity
 is_a: GO:0015296 {is_inferred="true"} ! anion:cation symporter activity
 
 [Term]
 id: GO:0015499 ! formate transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0008028 {is_inferred="true"} ! monocarboxylic acid transmembrane transporter activity
 
 [Term]
 id: GO:0015501 ! glutamate:sodium symporter activity
@@ -15089,6 +15274,10 @@
 is_a: GO:0005371 {is_inferred="true"} ! tricarboxylate secondary active transmembrane transporter activity
 
 [Term]
+id: GO:0015520 ! tetracycline:proton antiporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+
+[Term]
 id: GO:0015523 ! arabinose efflux transmembrane transporter activity
 is_a: GO:0015562 {is_inferred="true"} ! efflux transmembrane transporter activity
 is_a: GO:0042900 {is_inferred="true"} ! arabinose transmembrane transporter activity
@@ -15095,7 +15284,8 @@
 
 [Term]
 id: GO:0015530 ! shikimate transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0008028 {is_inferred="true"} ! monocarboxylic acid transmembrane transporter activity
+is_a: GO:1901618 {is_inferred="true"} ! organic hydroxy compound transmembrane transporter activity
 
 [Term]
 id: GO:0015531 ! citrate:proton symporter activity
@@ -15103,7 +15293,6 @@
 
 [Term]
 id: GO:0015539 ! hexuronate:cation symporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:0015296 {is_inferred="true"} ! anion:cation symporter activity
 
 [Term]
@@ -15112,7 +15301,7 @@
 
 [Term]
 id: GO:0015550 ! galacturonate transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0015134 {is_inferred="true"} ! hexuronate transmembrane transporter activity
 
 [Term]
 id: GO:0015551 ! 3-hydroxyphenyl propanoate transmembrane transporter activity
@@ -15120,8 +15309,8 @@
 
 [Term]
 id: GO:0015552 ! propionate transmembrane transporter activity
-is_a: GO:0005319 {is_inferred="true"} ! lipid transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0008028 {is_inferred="true"} ! monocarboxylic acid transmembrane transporter activity
+is_a: GO:0015635 {is_inferred="true"} ! short-chain fatty acid transporter activity
 
 [Term]
 id: GO:0015553 ! xanthosine transmembrane transporter activity
@@ -15132,10 +15321,6 @@
 is_a: GO:1901702 {is_inferred="true"} ! salt transmembrane transporter activity
 
 [Term]
-id: GO:0015556 ! C4-dicarboxylate transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
-
-[Term]
 id: GO:0015567 ! alkane transporter activity
 is_a: GO:0005215 {is_inferred="true"} ! transporter activity
 
@@ -15145,7 +15330,8 @@
 
 [Term]
 id: GO:0015569 ! p-aminobenzoyl-glutamate transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0005310 {is_inferred="true"} ! dicarboxylic acid transmembrane transporter activity
+is_a: GO:0071916 {is_inferred="true"} ! dipeptide transmembrane transporter activity
 
 [Term]
 id: GO:0015571 ! N-acetylgalactosamine transmembrane transporter activity
@@ -15192,6 +15378,22 @@
 is_a: GO:0015149 {is_inferred="true"} ! hexose transmembrane transporter activity
 
 [Term]
+id: GO:0015594 ! putrescine-importing ATPase activity
+is_a: GO:0019829 {is_inferred="true"} ! cation-transporting ATPase activity
+
+[Term]
+id: GO:0015595 ! spermidine-importing ATPase activity
+is_a: GO:0019829 {is_inferred="true"} ! cation-transporting ATPase activity
+
+[Term]
+id: GO:0015598 ! arginine-importing ATPase activity
+is_a: GO:0019829 {is_inferred="true"} ! cation-transporting ATPase activity
+
+[Term]
+id: GO:0015599 ! glutamine-importing ATPase activity
+is_a: GO:0019829 {is_inferred="true"} ! cation-transporting ATPase activity
+
+[Term]
 id: GO:0015604 ! organic phosphonate transmembrane transporter activity
 is_a: GO:0022857 {is_inferred="true"} ! transmembrane transporter activity
 
@@ -15200,7 +15402,14 @@
 is_a: GO:1901677 {is_inferred="true"} ! phosphate transmembrane transporter activity
 
 [Term]
+id: GO:0015606 ! spermidine transmembrane transporter activity
+is_a: GO:0008519 {is_inferred="true"} ! ammonium transmembrane transporter activity
+is_a: GO:0015101 {is_inferred="true"} ! organic cation transmembrane transporter activity
+
+[Term]
 id: GO:0015619 ! thiamine pyrophosphate-transporting ATPase activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0015101 {is_inferred="true"} ! organic cation transmembrane transporter activity
 is_a: GO:0015605 {is_inferred="true"} ! organophosphate ester transmembrane transporter activity
 
 [Term]
@@ -15235,6 +15444,14 @@
 is_a: GO:0015563 {is_inferred="true"} ! uptake transmembrane transporter activity
 
 [Term]
+id: GO:0015655 ! alanine:sodium symporter activity
+is_a: GO:0015296 {is_inferred="true"} ! anion:cation symporter activity
+
+[Term]
+id: GO:0015657 ! branched-chain amino acid:sodium symporter activity
+is_a: GO:0015296 {is_inferred="true"} ! anion:cation symporter activity
+
+[Term]
 id: GO:0015658 ! branched-chain amino acid transmembrane transporter activity
 is_a: GO:0015171 {is_inferred="true"} ! amino acid transmembrane transporter activity
 
@@ -15303,8 +15520,8 @@
 
 [Term]
 id: GO:0015685 ! ferric-enterobactin transport
+is_a: GO:0015688 {is_inferred="true"} ! iron chelate transport
 is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
-is_a: GO:1901678 {is_inferred="true"} ! iron coordination entity transport
 
 [Term]
 id: GO:0015686 ! ferric triacetylfusarinine C transport
@@ -15378,7 +15595,7 @@
 [Term]
 id: GO:0015704 ! cyanate transport
 is_a: GO:0006820 {is_inferred="true"} ! anion transport
-is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
+is_a: GO:0019755 {is_inferred="true"} ! one-carbon compound transport
 is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
@@ -15406,7 +15623,7 @@
 
 [Term]
 id: GO:0015710 ! tellurite transport
-is_a: GO:0006820 {is_inferred="true"} ! anion transport
+is_a: GO:0015698 {is_inferred="true"} ! inorganic anion transport
 
 [Term]
 id: GO:0015711 ! organic anion transport
@@ -15420,15 +15637,19 @@
 
 [Term]
 id: GO:0015713 ! phosphoglycerate transport
+is_a: GO:0015748 {is_inferred="true"} ! organophosphate ester transport
 is_a: GO:0042873 {is_inferred="true"} ! aldonate transport
+is_a: GO:1901264 {is_inferred="true"} ! carbohydrate derivative transport
 
 [Term]
 id: GO:0015714 ! phosphoenolpyruvate transport
 is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
+is_a: GO:0015748 {is_inferred="true"} ! organophosphate ester transport
 
 [Term]
 id: GO:0015715 ! nucleotide-sulfate transport
 is_a: GO:0006862 {is_inferred="true"} ! nucleotide transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0072348 {is_inferred="true"} ! sulfur compound transport
 
 [Term]
@@ -15457,17 +15678,16 @@
 [Term]
 id: GO:0015721 ! bile acid and bile salt transport
 is_a: GO:0006869 {is_inferred="true"} ! lipid transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
 is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
 
 [Term]
 id: GO:0015722 ! canalicular bile acid transport
-is_a: GO:0015721 {is_inferred="true"} ! bile acid and bile salt transport
-is_a: GO:0046717 {is_inferred="true"} ! acid secretion
+is_a: GO:0032782 {is_inferred="true"} ! bile acid secretion
 
 [Term]
 id: GO:0015723 ! bilirubin transport
 is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
+is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
 id: GO:0015724 ! formate transport
@@ -15484,10 +15704,12 @@
 [Term]
 id: GO:0015727 ! lactate transport
 is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
+is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
 
 [Term]
 id: GO:0015728 ! mevalonate transport
 is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
+is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
 
 [Term]
 id: GO:0015729 ! oxaloacetate transport
@@ -15509,10 +15731,11 @@
 [Term]
 id: GO:0015733 ! shikimate transport
 is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
+is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
 
 [Term]
 id: GO:0015734 ! taurine transport
-is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
+is_a: GO:0042918 {is_inferred="true"} ! alkanesulfonate transport
 is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 is_a: GO:0072348 {is_inferred="true"} ! sulfur compound transport
 
@@ -15519,6 +15742,7 @@
 [Term]
 id: GO:0015735 ! uronic acid transport
 is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
+is_a: GO:0015749 {is_inferred="true"} ! monosaccharide transport
 
 [Term]
 id: GO:0015736 ! hexuronate transport
@@ -15535,6 +15759,7 @@
 [Term]
 id: GO:0015739 ! sialic acid transport
 is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:1901264 {is_inferred="true"} ! carbohydrate derivative transport
 
 [Term]
 id: GO:0015740 ! C4-dicarboxylate transport
@@ -15558,6 +15783,7 @@
 
 [Term]
 id: GO:0015745 ! tartrate transport
+is_a: GO:0015740 {is_inferred="true"} ! C4-dicarboxylate transport
 is_a: GO:0042869 {is_inferred="true"} ! aldarate transport
 
 [Term]
@@ -15567,6 +15793,7 @@
 [Term]
 id: GO:0015747 ! urate transport
 is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
+is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
 id: GO:0015748 ! organophosphate ester transport
@@ -15686,6 +15913,7 @@
 
 [Term]
 id: GO:0015779 ! glucuronoside transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
 is_a: GO:1901656 {is_inferred="true"} ! glycoside transport
 
 [Term]
@@ -15699,6 +15927,7 @@
 
 [Term]
 id: GO:0015782 ! CMP-N-acetylneuraminate transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015781 {is_inferred="true"} ! pyrimidine nucleotide-sugar transport
 
 [Term]
@@ -15711,26 +15940,32 @@
 
 [Term]
 id: GO:0015785 ! UDP-galactose transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015781 {is_inferred="true"} ! pyrimidine nucleotide-sugar transport
 
 [Term]
 id: GO:0015786 ! UDP-glucose transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015781 {is_inferred="true"} ! pyrimidine nucleotide-sugar transport
 
 [Term]
 id: GO:0015787 ! UDP-glucuronic acid transport
 is_a: GO:0015781 {is_inferred="true"} ! pyrimidine nucleotide-sugar transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
 
 [Term]
 id: GO:0015788 ! UDP-N-acetylglucosamine transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015781 {is_inferred="true"} ! pyrimidine nucleotide-sugar transport
 
 [Term]
 id: GO:0015789 ! UDP-N-acetylgalactosamine transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015781 {is_inferred="true"} ! pyrimidine nucleotide-sugar transport
 
 [Term]
 id: GO:0015790 ! UDP-xylose transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015781 {is_inferred="true"} ! pyrimidine nucleotide-sugar transport
 
 [Term]
@@ -15749,6 +15984,7 @@
 
 [Term]
 id: GO:0015794 ! glycerol-3-phosphate transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015748 {is_inferred="true"} ! organophosphate ester transport
 is_a: GO:1901264 {is_inferred="true"} ! carbohydrate derivative transport
 
@@ -15785,16 +16021,17 @@
 
 [Term]
 id: GO:0015805 ! S-adenosyl-L-methionine transport
+is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 is_a: GO:0072348 {is_inferred="true"} ! sulfur compound transport
 
 [Term]
 id: GO:0015806 ! S-methylmethionine transport
+is_a: GO:0072337 {is_inferred="true"} ! modified amino acid transport
 is_a: GO:0072348 {is_inferred="true"} ! sulfur compound transport
 
 [Term]
 id: GO:0015807 ! L-amino acid transport
-is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
+is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
 
 [Term]
 id: GO:0015808 ! L-alanine transport
@@ -15803,7 +16040,7 @@
 
 [Term]
 id: GO:0015809 ! arginine transport
-is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
 
 [Term]
 id: GO:0015810 ! aspartate transport
@@ -15812,12 +16049,13 @@
 [Term]
 id: GO:0015811 ! L-cystine transport
 is_a: GO:0000101 {is_inferred="true"} ! sulfur amino acid transport
+is_a: GO:0015807 {is_inferred="true"} ! L-amino acid transport
 is_a: GO:0072337 {is_inferred="true"} ! modified amino acid transport
 
 [Term]
 id: GO:0015812 ! gamma-aminobutyric acid transport
-is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
+is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
+is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
 
 [Term]
 id: GO:0015813 ! L-glutamate transport
@@ -15827,68 +16065,79 @@
 [Term]
 id: GO:0015814 ! p-aminobenzoyl-glutamate transport
 is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
+is_a: GO:0042938 {is_inferred="true"} ! dipeptide transport
+is_a: GO:0072337 {is_inferred="true"} ! modified amino acid transport
 
 [Term]
 id: GO:0015816 ! glycine transport
-is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
+is_a: GO:0015807 {is_inferred="true"} ! L-amino acid transport
 
 [Term]
 id: GO:0015817 ! histidine transport
-is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
+is_a: GO:0045117 {is_inferred="true"} ! azole transport
 
 [Term]
 id: GO:0015818 ! isoleucine transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
 is_a: GO:0015803 {is_inferred="true"} ! branched-chain amino acid transport
 
 [Term]
 id: GO:0015819 ! lysine transport
-is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
 
 [Term]
 id: GO:0015820 ! leucine transport
-is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
+is_a: GO:0015803 {is_inferred="true"} ! branched-chain amino acid transport
 
 [Term]
 id: GO:0015821 ! methionine transport
-is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
+is_a: GO:0000101 {is_inferred="true"} ! sulfur amino acid transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
 
 [Term]
 id: GO:0015822 ! ornithine transport
-is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
+is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
 
 [Term]
 id: GO:0015823 ! phenylalanine transport
-is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
+is_a: GO:0015801 {is_inferred="true"} ! aromatic amino acid transport
 
 [Term]
 id: GO:0015824 ! proline transport
-is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
 
 [Term]
 id: GO:0015825 ! L-serine transport
 is_a: GO:0015807 {is_inferred="true"} ! L-amino acid transport
+is_a: GO:0032329 {is_inferred="true"} ! serine transport
 
 [Term]
 id: GO:0015826 ! threonine transport
-is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
 
 [Term]
 id: GO:0015827 ! tryptophan transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
 is_a: GO:0015801 {is_inferred="true"} ! aromatic amino acid transport
 
 [Term]
 id: GO:0015828 ! tyrosine transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
 is_a: GO:0015801 {is_inferred="true"} ! aromatic amino acid transport
 
 [Term]
 id: GO:0015829 ! valine transport
-is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
+is_a: GO:0015803 {is_inferred="true"} ! branched-chain amino acid transport
 
 [Term]
 id: GO:0015830 ! diaminopimelate transport
+is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
 is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
 
 [Term]
@@ -15916,8 +16165,8 @@
 
 [Term]
 id: GO:0015839 ! cadaverine transport
-is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
+is_a: GO:0015695 {is_inferred="true"} ! organic cation transport
+is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 
 [Term]
 id: GO:0015840 ! urea transport
@@ -15935,7 +16184,10 @@
 
 [Term]
 id: GO:0015843 ! methylammonium transport
+is_a: GO:0015695 {is_inferred="true"} ! organic cation transport
 is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
+is_a: GO:0015837 {is_inferred="true"} ! amine transport
+is_a: GO:0019755 {is_inferred="true"} ! one-carbon compound transport
 
 [Term]
 id: GO:0015844 ! monoamine transport
@@ -15948,6 +16200,16 @@
 is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
+id: GO:0015847 ! putrescine transport
+is_a: GO:0015695 {is_inferred="true"} ! organic cation transport
+is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
+
+[Term]
+id: GO:0015848 ! spermidine transport
+is_a: GO:0015695 {is_inferred="true"} ! organic cation transport
+is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
+
+[Term]
 id: GO:0015849 ! organic acid transport
 is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 
@@ -16016,6 +16278,7 @@
 
 [Term]
 id: GO:0015866 ! ADP transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015858 {is_inferred="true"} ! nucleoside transport
 is_a: GO:0015868 {is_inferred="true"} ! purine ribonucleotide transport
 is_a: GO:0051503 {is_inferred="true"} ! adenine nucleotide transport
@@ -16022,6 +16285,7 @@
 
 [Term]
 id: GO:0015867 ! ATP transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015858 {is_inferred="true"} ! nucleoside transport
 is_a: GO:0015868 {is_inferred="true"} ! purine ribonucleotide transport
 is_a: GO:0051503 {is_inferred="true"} ! adenine nucleotide transport
@@ -16046,6 +16310,7 @@
 
 [Term]
 id: GO:0015872 ! dopamine transport
+is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 is_a: GO:0051937 {is_inferred="true"} ! catecholamine transport
 
 [Term]
@@ -16064,13 +16329,17 @@
 [Term]
 id: GO:0015878 ! biotin transport
 is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
+is_a: GO:0042886 {is_inferred="true"} ! amide transport
+is_a: GO:0072348 {is_inferred="true"} ! sulfur compound transport
 
 [Term]
 id: GO:0015879 ! carnitine transport
+is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 is_a: GO:0015838 {is_inferred="true"} ! amino-acid betaine transport
 
 [Term]
 id: GO:0015880 ! coenzyme A transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015858 {is_inferred="true"} ! nucleoside transport
 is_a: GO:0015868 {is_inferred="true"} ! purine ribonucleotide transport
 is_a: GO:0051503 {is_inferred="true"} ! adenine nucleotide transport
@@ -16077,24 +16346,29 @@
 
 [Term]
 id: GO:0015881 ! creatine transport
+is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
 is_a: GO:0072337 {is_inferred="true"} ! modified amino acid transport
 
 [Term]
 id: GO:0015882 ! L-ascorbic acid transport
+is_a: GO:0015749 {is_inferred="true"} ! monosaccharide transport
 is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
 
 [Term]
 id: GO:0015883 ! FAD transport
 is_a: GO:0006862 {is_inferred="true"} ! nucleotide transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 
 [Term]
 id: GO:0015884 ! folic acid transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
+is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
 is_a: GO:0042886 {is_inferred="true"} ! amide transport
 is_a: GO:0072337 {is_inferred="true"} ! modified amino acid transport
 
 [Term]
 id: GO:0015885 ! 5-formyltetrahydrofolate transport
+is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
+is_a: GO:0042886 {is_inferred="true"} ! amide transport
 is_a: GO:0072337 {is_inferred="true"} ! modified amino acid transport
 
 [Term]
@@ -16106,7 +16380,9 @@
 [Term]
 id: GO:0015887 ! pantothenate transmembrane transport
 is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:0042886 {is_inferred="true"} ! amide transport
+is_a: GO:0072337 {is_inferred="true"} ! modified amino acid transport
+is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
 id: GO:0015888 ! thiamine transport
@@ -16130,6 +16406,7 @@
 [Term]
 id: GO:0015896 ! nalidixic acid transport
 is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
+is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
 id: GO:0015897 ! organomercurial transport
@@ -16137,8 +16414,8 @@
 
 [Term]
 id: GO:0015898 ! amiloride transport
+is_a: GO:0015695 {is_inferred="true"} ! organic cation transport
 is_a: GO:0042886 {is_inferred="true"} ! amide transport
-is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 
 [Term]
 id: GO:0015899 ! aminotriazole transport
@@ -16166,7 +16443,7 @@
 
 [Term]
 id: GO:0015904 ! tetracycline transport
-is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 
 [Term]
 id: GO:0015905 ! bicyclomycin transport
@@ -16189,25 +16466,22 @@
 is_a: GO:0015908 {is_inferred="true"} ! fatty acid transport
 
 [Term]
-id: GO:0015911 ! plasma membrane long-chain fatty acid transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
-
-[Term]
 id: GO:0015912 ! short-chain fatty acid transport
 is_a: GO:0015908 {is_inferred="true"} ! fatty acid transport
 
 [Term]
 id: GO:0015913 ! short-chain fatty acid import
-is_a: GO:0006869 {is_inferred="true"} ! lipid transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
+is_a: GO:0015912 {is_inferred="true"} ! short-chain fatty acid transport
 
 [Term]
 id: GO:0015914 ! phospholipid transport
 is_a: GO:0006869 {is_inferred="true"} ! lipid transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015748 {is_inferred="true"} ! organophosphate ester transport
 
 [Term]
 id: GO:0015916 ! fatty-acyl-CoA transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:1901337 {is_inferred="true"} ! thioester transport
 
 [Term]
@@ -16259,16 +16533,21 @@
 
 [Term]
 id: GO:0015939 ! pantothenate metabolic process
+is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0043603 {is_inferred="true"} ! cellular amide metabolic process
 
 [Term]
 id: GO:0015940 ! pantothenate biosynthetic process
 is_a: GO:0015939 {is_inferred="true"} ! pantothenate metabolic process
+is_a: GO:0042398 {is_inferred="true"} ! cellular modified amino acid biosynthetic process
+is_a: GO:0043604 {is_inferred="true"} ! amide biosynthetic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 
 [Term]
 id: GO:0015941 ! pantothenate catabolic process
 is_a: GO:0015939 {is_inferred="true"} ! pantothenate metabolic process
+is_a: GO:0042219 {is_inferred="true"} ! cellular modified amino acid catabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 
 [Term]
@@ -16866,6 +17145,8 @@
 id: GO:0016208 ! AMP binding
 is_a: GO:0032550 {is_inferred="true"} ! purine ribonucleoside binding
 is_a: GO:0032559 {is_inferred="true"} ! adenyl ribonucleotide binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
+is_a: GO:0043169 {is_inferred="true"} ! cation binding
 
 [Term]
 id: GO:0016222 ! procollagen-proline 4-dioxygenase complex
@@ -17028,10 +17309,11 @@
 [Term]
 id: GO:0016594 ! glycine binding
 is_a: GO:0016597 {is_inferred="true"} ! amino acid binding
+is_a: GO:0043169 {is_inferred="true"} ! cation binding
 
 [Term]
 id: GO:0016595 ! glutamate binding
-is_a: GO:0031406 {is_inferred="true"} ! carboxylic acid binding
+is_a: GO:0016597 {is_inferred="true"} ! amino acid binding
 
 [Term]
 id: GO:0016596 ! thienylcyclohexylpiperidine binding
@@ -17173,6 +17455,7 @@
 is_a: GO:0006024 {is_inferred="true"} ! glycosaminoglycan biosynthetic process
 is_a: GO:0042339 {is_inferred="true"} ! keratan sulfate metabolic process
 is_a: GO:0044272 {is_inferred="true"} ! sulfur compound biosynthetic process
+is_a: GO:0044711 {is_inferred="true"} ! single-organism biosynthetic process
 
 [Term]
 id: GO:0018158 ! protein oxidation
@@ -17192,7 +17475,11 @@
 
 [Term]
 id: GO:0018189 ! pyrroloquinoline quinone biosynthetic process
+is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
 is_a: GO:0072351 {is_inferred="true"} ! tricarboxylic acid biosynthetic process
+is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
+is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
+is_a: GO:1901663 {is_inferred="true"} ! quinone biosynthetic process
 
 [Term]
 id: GO:0018396 ! peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine
@@ -17201,17 +17488,17 @@
 
 [Term]
 id: GO:0018397 ! peptidyl-phenylalanine bromination to L-2'-bromophenylalanine
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
 is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
 
 [Term]
 id: GO:0018398 ! peptidyl-phenylalanine bromination to L-3'-bromophenylalanine
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
 is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
 
 [Term]
 id: GO:0018399 ! peptidyl-phenylalanine bromination to L-4'-bromophenylalanine
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
 is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
 
 [Term]
@@ -17247,15 +17534,17 @@
 
 [Term]
 id: GO:0018868 ! 2-aminobenzenesulfonate metabolic process
+is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
 is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 
 [Term]
 id: GO:0018871 ! 1-aminocyclopropane-1-carboxylate metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
 
 [Term]
 id: GO:0018872 ! arsonoacetate metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 
 [Term]
 id: GO:0018873 ! atrazine metabolic process
@@ -17264,6 +17553,7 @@
 [Term]
 id: GO:0018874 ! benzoate metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 
 [Term]
 id: GO:0018876 ! benzonitrile metabolic process
@@ -17312,9 +17602,9 @@
 
 [Term]
 id: GO:0018887 ! 4-carboxy-4'-sulfoazobenzene metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
 is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
 is_a: GO:0006807 {is_inferred="true"} ! nitrogen compound metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 
 [Term]
@@ -17371,6 +17661,7 @@
 [Term]
 id: GO:0018898 ! 2,4-dichlorobenzoate metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 
 [Term]
 id: GO:0018899 ! 1,2-dichloroethane metabolic process
@@ -17382,7 +17673,9 @@
 
 [Term]
 id: GO:0018901 ! 2,4-dichlorophenoxyacetic acid metabolic process
+is_a: GO:0018904 {is_inferred="true"} ! ether metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 
 [Term]
 id: GO:0018902 ! 1,3-dichloro-2-propanol metabolic process
@@ -17449,7 +17742,9 @@
 
 [Term]
 id: GO:0018918 ! gallate metabolic process
+is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 
 [Term]
 id: GO:0018919 ! gamma-1,2,3,4,5,6-hexachlorocyclohexane metabolic process
@@ -17459,6 +17754,7 @@
 id: GO:0018920 ! glyphosate metabolic process
 is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
 is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
+is_a: GO:0043436 {is_inferred="true"} ! oxoacid metabolic process
 
 [Term]
 id: GO:0018921 ! 3-hydroxybenzyl alcohol metabolic process
@@ -17479,6 +17775,8 @@
 [Term]
 id: GO:0018924 ! mandelate metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
+is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
 
 [Term]
 id: GO:0018925 ! m-cresol metabolic process
@@ -17486,6 +17784,7 @@
 
 [Term]
 id: GO:0018926 ! methanesulfonic acid metabolic process
+is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
 is_a: GO:0019694 {is_inferred="true"} ! alkanesulfonate metabolic process
 
 [Term]
@@ -17617,6 +17916,7 @@
 [Term]
 id: GO:0018962 ! 3-phenylpropionate metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 
 [Term]
 id: GO:0018963 ! phthalate metabolic process
@@ -17656,6 +17956,11 @@
 is_a: GO:0072490 {is_inferred="true"} ! toluene-containing compound metabolic process
 
 [Term]
+id: GO:0018972 ! toluene-4-sulfonate metabolic process
+is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
+is_a: GO:0072490 {is_inferred="true"} ! toluene-containing compound metabolic process
+
+[Term]
 id: GO:0018973 ! trinitrotoluene metabolic process
 is_a: GO:0019326 {is_inferred="true"} ! nitrotoluene metabolic process
 
@@ -17678,7 +17983,9 @@
 
 [Term]
 id: GO:0018980 ! 2,4,5-trichlorophenoxyacetic acid metabolic process
+is_a: GO:0018904 {is_inferred="true"} ! ether metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 
 [Term]
 id: GO:0018981 ! triethanolamine metabolic process
@@ -17711,11 +18018,13 @@
 id: GO:0019002 ! GMP binding
 is_a: GO:0032550 {is_inferred="true"} ! purine ribonucleoside binding
 is_a: GO:0032561 {is_inferred="true"} ! guanyl ribonucleotide binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
 [Term]
 id: GO:0019003 ! GDP binding
 is_a: GO:0032550 {is_inferred="true"} ! purine ribonucleoside binding
 is_a: GO:0032561 {is_inferred="true"} ! guanyl ribonucleotide binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
 [Term]
 id: GO:0019038 ! provirus
@@ -17839,6 +18148,7 @@
 id: GO:0019249 ! lactate biosynthetic process
 is_a: GO:0006089 {is_inferred="true"} ! lactate metabolic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
+is_a: GO:1901617 {is_inferred="true"} ! organic hydroxy compound biosynthetic process
 
 [Term]
 id: GO:0019252 ! starch biosynthetic process
@@ -17879,6 +18189,7 @@
 [Term]
 id: GO:0019262 ! N-acetylneuraminate catabolic process
 is_a: GO:0006054 {is_inferred="true"} ! N-acetylneuraminate metabolic process
+is_a: GO:0046348 {is_inferred="true"} ! amino sugar catabolic process
 is_a: GO:0046395 {is_inferred="true"} ! carboxylic acid catabolic process
 
 [Term]
@@ -17906,9 +18217,11 @@
 id: GO:0019270 ! aerobactin biosynthetic process
 is_a: GO:0042398 {is_inferred="true"} ! cellular modified amino acid biosynthetic process
 is_a: GO:0046442 {is_inferred="true"} ! aerobactin metabolic process
+is_a: GO:0072351 {is_inferred="true"} ! tricarboxylic acid biosynthetic process
 
 [Term]
 id: GO:0019271 ! aerobactin transport
+is_a: GO:0006842 {is_inferred="true"} ! tricarboxylic acid transport
 is_a: GO:0072337 {is_inferred="true"} ! modified amino acid transport
 
 [Term]
@@ -17919,6 +18232,7 @@
 [Term]
 id: GO:0019276 ! UDP-N-acetylgalactosamine metabolic process
 is_a: GO:0006040 {is_inferred="true"} ! amino sugar metabolic process
+is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
 is_a: GO:0009225 {is_inferred="true"} ! nucleotide-sugar metabolic process
 
 [Term]
@@ -17935,7 +18249,6 @@
 
 [Term]
 id: GO:0019283 ! L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine
-is_a: GO:0000097 {is_inferred="true"} ! sulfur amino acid biosynthetic process
 is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
 is_a: GO:0006796 {is_inferred="true"} ! phosphate-containing compound metabolic process
 is_a: GO:0019637 {is_inferred="true"} ! organophosphate metabolic process
@@ -17942,7 +18255,6 @@
 
 [Term]
 id: GO:0019284 ! L-methionine biosynthetic process from S-adenosylmethionine
-is_a: GO:0000097 {is_inferred="true"} ! sulfur amino acid biosynthetic process
 is_a: GO:0046500 {is_inferred="true"} ! S-adenosylmethionine metabolic process
 
 [Term]
@@ -17958,7 +18270,7 @@
 
 [Term]
 id: GO:0019289 ! rhizobactin 1021 biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
+is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 is_a: GO:1902645 {is_inferred="true"} ! tertiary alcohol biosynthetic process
 
 [Term]
@@ -17968,6 +18280,7 @@
 
 [Term]
 id: GO:0019294 ! keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
+is_a: GO:0046364 {is_inferred="true"} ! monosaccharide biosynthetic process
 is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 is_a: GO:0046400 {is_inferred="true"} ! keto-3-deoxy-D-manno-octulosonic acid metabolic process
 
@@ -17987,11 +18300,14 @@
 [Term]
 id: GO:0019297 ! coenzyme B metabolic process
 is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
+is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 
 [Term]
 id: GO:0019298 ! coenzyme B biosynthetic process
 is_a: GO:0019297 {is_inferred="true"} ! coenzyme B metabolic process
 is_a: GO:0042398 {is_inferred="true"} ! cellular modified amino acid biosynthetic process
+is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 
 [Term]
 id: GO:0019299 ! rhamnose metabolic process
@@ -18184,6 +18500,7 @@
 
 [Term]
 id: GO:0019344 ! cysteine biosynthetic process
+is_a: GO:0000097 {is_inferred="true"} ! sulfur amino acid biosynthetic process
 is_a: GO:0006534 {is_inferred="true"} ! cysteine metabolic process
 
 [Term]
@@ -18213,8 +18530,12 @@
 
 [Term]
 id: GO:0019351 ! dethiobiotin biosynthetic process
+is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
+is_a: GO:0043604 {is_inferred="true"} ! amide biosynthetic process
 is_a: GO:0046450 {is_inferred="true"} ! dethiobiotin metabolic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
+is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
+is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
 
 [Term]
 id: GO:0019352 ! protoporphyrinogen IX biosynthetic process from glycine
@@ -18315,7 +18636,9 @@
 [Term]
 id: GO:0019380 ! 3-phenylpropionate catabolic process
 is_a: GO:0018962 {is_inferred="true"} ! 3-phenylpropionate metabolic process
+is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
+is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
 
 [Term]
 id: GO:0019381 ! atrazine catabolic process
@@ -18361,13 +18684,14 @@
 [Term]
 id: GO:0019389 ! glucuronoside metabolic process
 is_a: GO:0016137 {is_inferred="true"} ! glycoside metabolic process
+is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 is_a: GO:0044723 {is_inferred="true"} ! single-organism carbohydrate metabolic process
-is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
 
 [Term]
 id: GO:0019390 ! glucuronoside biosynthetic process
 is_a: GO:0016138 {is_inferred="true"} ! glycoside biosynthetic process
 is_a: GO:0019389 {is_inferred="true"} ! glucuronoside metabolic process
+is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 
 [Term]
 id: GO:0019391 ! glucuronoside catabolic process
@@ -18374,6 +18698,7 @@
 is_a: GO:0016139 {is_inferred="true"} ! glycoside catabolic process
 is_a: GO:0019389 {is_inferred="true"} ! glucuronoside metabolic process
 is_a: GO:0044724 {is_inferred="true"} ! single-organism carbohydrate catabolic process
+is_a: GO:0046395 {is_inferred="true"} ! carboxylic acid catabolic process
 
 [Term]
 id: GO:0019392 ! glucarate metabolic process
@@ -18392,6 +18717,7 @@
 [Term]
 id: GO:0019396 ! gallate catabolic process
 is_a: GO:0018918 {is_inferred="true"} ! gallate metabolic process
+is_a: GO:0019336 {is_inferred="true"} ! phenol-containing compound catabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 
 [Term]
@@ -18527,7 +18853,7 @@
 [Term]
 id: GO:0019440 ! tryptophan catabolic process to indole-3-acetate
 is_a: GO:0006569 {is_inferred="true"} ! tryptophan catabolic process
-is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0009683 {is_inferred="true"} ! indoleacetic acid metabolic process
 
 [Term]
 id: GO:0019441 ! tryptophan catabolic process to kynurenine
@@ -18552,22 +18878,23 @@
 [Term]
 id: GO:0019446 ! tyrosine catabolic process to phosphoenolpyruvate
 is_a: GO:0006572 {is_inferred="true"} ! tyrosine catabolic process
+is_a: GO:0006796 {is_inferred="true"} ! phosphate-containing compound metabolic process
+is_a: GO:0019637 {is_inferred="true"} ! organophosphate metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 
 [Term]
 id: GO:0019447 ! D-cysteine catabolic process
-is_a: GO:0000098 {is_inferred="true"} ! sulfur amino acid catabolic process
+is_a: GO:0009093 {is_inferred="true"} ! cysteine catabolic process
+is_a: GO:0019478 {is_inferred="true"} ! D-amino acid catabolic process
 is_a: GO:0046438 {is_inferred="true"} ! D-cysteine metabolic process
-is_a: GO:1901606 {is_inferred="true"} ! alpha-amino acid catabolic process
 
 [Term]
 id: GO:0019448 ! L-cysteine catabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
+is_a: GO:0009093 {is_inferred="true"} ! cysteine catabolic process
 is_a: GO:0046439 {is_inferred="true"} ! L-cysteine metabolic process
 
 [Term]
 id: GO:0019449 ! L-cysteine catabolic process to hypotaurine
-is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
 is_a: GO:0019448 {is_inferred="true"} ! L-cysteine catabolic process
 
 [Term]
@@ -18594,7 +18921,6 @@
 [Term]
 id: GO:0019463 ! glycine catabolic process to creatine
 is_a: GO:0006546 {is_inferred="true"} ! glycine catabolic process
-is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
 is_a: GO:0006600 {is_inferred="true"} ! creatine metabolic process
 
 [Term]
@@ -18603,14 +18929,16 @@
 
 [Term]
 id: GO:0019468 ! nopaline catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
 is_a: GO:0042219 {is_inferred="true"} ! cellular modified amino acid catabolic process
 is_a: GO:0046418 {is_inferred="true"} ! nopaline metabolic process
+is_a: GO:0072352 {is_inferred="true"} ! tricarboxylic acid catabolic process
+is_a: GO:1901606 {is_inferred="true"} ! alpha-amino acid catabolic process
 
 [Term]
 id: GO:0019469 ! octopine catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
+is_a: GO:0019478 {is_inferred="true"} ! D-amino acid catabolic process
 is_a: GO:0042219 {is_inferred="true"} ! cellular modified amino acid catabolic process
+is_a: GO:0043649 {is_inferred="true"} ! dicarboxylic acid catabolic process
 is_a: GO:0046419 {is_inferred="true"} ! octopine metabolic process
 
 [Term]
@@ -18643,6 +18971,7 @@
 [Term]
 id: GO:0019476 ! D-lysine catabolic process
 is_a: GO:0006554 {is_inferred="true"} ! lysine catabolic process
+is_a: GO:0019478 {is_inferred="true"} ! D-amino acid catabolic process
 is_a: GO:0046441 {is_inferred="true"} ! D-lysine metabolic process
 
 [Term]
@@ -18652,25 +18981,22 @@
 
 [Term]
 id: GO:0019478 ! D-amino acid catabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
 is_a: GO:0046416 {is_inferred="true"} ! D-amino acid metabolic process
+is_a: GO:1901606 {is_inferred="true"} ! alpha-amino acid catabolic process
 
 [Term]
 id: GO:0019482 ! beta-alanine metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
+is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
 
 [Term]
 id: GO:0019483 ! beta-alanine biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
+is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 is_a: GO:0019482 {is_inferred="true"} ! beta-alanine metabolic process
-is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
 
 [Term]
 id: GO:0019484 ! beta-alanine catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
+is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
 is_a: GO:0019482 {is_inferred="true"} ! beta-alanine metabolic process
-is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
 
 [Term]
 id: GO:0019485 ! beta-alanine catabolic process to L-alanine
@@ -18684,13 +19010,15 @@
 
 [Term]
 id: GO:0019489 ! methylgallate metabolic process
+is_a: GO:0009712 {is_inferred="true"} ! catechol-containing compound metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 
 [Term]
 id: GO:0019491 ! ectoine biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
 is_a: GO:0042399 {is_inferred="true"} ! ectoine metabolic process
+is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
 is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
 
@@ -18711,16 +19039,18 @@
 [Term]
 id: GO:0019499 ! cyanide metabolic process
 is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
+is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
 
 [Term]
 id: GO:0019500 ! cyanide catabolic process
 is_a: GO:0019499 {is_inferred="true"} ! cyanide metabolic process
 is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
+is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
 
 [Term]
 id: GO:0019501 ! arsonoacetate catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
 is_a: GO:0018872 {is_inferred="true"} ! arsonoacetate metabolic process
+is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 
 [Term]
 id: GO:0019502 ! stachydrine metabolic process
@@ -18727,6 +19057,7 @@
 is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
 is_a: GO:0006577 {is_inferred="true"} ! amino-acid betaine metabolic process
 is_a: GO:0009820 {is_inferred="true"} ! alkaloid metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
 
 [Term]
@@ -18835,16 +19166,19 @@
 id: GO:0019529 ! taurine catabolic process
 is_a: GO:0019530 {is_inferred="true"} ! taurine metabolic process
 is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
+is_a: GO:0046306 {is_inferred="true"} ! alkanesulfonate catabolic process
 is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
 
 [Term]
 id: GO:0019530 ! taurine metabolic process
 is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
+is_a: GO:0019694 {is_inferred="true"} ! alkanesulfonate metabolic process
+is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
 is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
 
 [Term]
 id: GO:0019531 ! oxalate transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0005310 {is_inferred="true"} ! dicarboxylic acid transmembrane transporter activity
 
 [Term]
 id: GO:0019532 ! oxalate transport
@@ -18877,6 +19211,10 @@
 is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
 
 [Term]
+id: GO:0019539 ! siderophore biosynthetic process from hydroxamic acid
+is_a: GO:0043436 {is_inferred="true"} ! oxoacid metabolic process
+
+[Term]
 id: GO:0019540 ! siderophore biosynthetic process from catechol
 is_a: GO:0009712 {is_inferred="true"} ! catechol-containing compound metabolic process
 
@@ -18957,6 +19295,8 @@
 
 [Term]
 id: GO:0019562 ! phenylalanine catabolic process to phosphoenolpyruvate
+is_a: GO:0006796 {is_inferred="true"} ! phosphate-containing compound metabolic process
+is_a: GO:0019637 {is_inferred="true"} ! organophosphate metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 
 [Term]
@@ -19019,6 +19359,7 @@
 
 [Term]
 id: GO:0019578 ! aldaric acid biosynthetic process
+is_a: GO:0016051 {is_inferred="true"} ! carbohydrate biosynthetic process
 is_a: GO:0019577 {is_inferred="true"} ! aldaric acid metabolic process
 is_a: GO:0043650 {is_inferred="true"} ! dicarboxylic acid biosynthetic process
 
@@ -19074,12 +19415,17 @@
 [Term]
 id: GO:0019596 ! mandelate catabolic process
 is_a: GO:0018924 {is_inferred="true"} ! mandelate metabolic process
+is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
+is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
+is_a: GO:1901616 {is_inferred="true"} ! organic hydroxy compound catabolic process
 
 [Term]
 id: GO:0019597 ! (R)-mandelate catabolic process to benzoate
 is_a: GO:0018874 {is_inferred="true"} ! benzoate metabolic process
+is_a: GO:0019438 {is_inferred="true"} ! aromatic compound biosynthetic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
+is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
 
 [Term]
 id: GO:0019598 ! (R)-mandelate catabolic process to catechol
@@ -19118,10 +19464,12 @@
 
 [Term]
 id: GO:0019609 ! 3-hydroxyphenylacetate metabolic process
+is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 
 [Term]
 id: GO:0019610 ! 3-hydroxyphenylacetate catabolic process
+is_a: GO:0019336 {is_inferred="true"} ! phenol-containing compound catabolic process
 is_a: GO:0019609 {is_inferred="true"} ! 3-hydroxyphenylacetate metabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 
@@ -19128,11 +19476,14 @@
 [Term]
 id: GO:0019611 ! 4-toluenecarboxylate metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 
 [Term]
 id: GO:0019612 ! 4-toluenecarboxylate catabolic process
+is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
 is_a: GO:0019611 {is_inferred="true"} ! 4-toluenecarboxylate metabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
+is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
 
 [Term]
 id: GO:0019614 ! catechol-containing compound catabolic process
@@ -19145,7 +19496,12 @@
 is_a: GO:0006107 {is_inferred="true"} ! oxaloacetate metabolic process
 
 [Term]
+id: GO:0019618 ! protocatechuate catabolic process, ortho-cleavage
+is_a: GO:0043648 {is_inferred="true"} ! dicarboxylic acid metabolic process
+
+[Term]
 id: GO:0019619 ! 3,4-dihydroxybenzoate catabolic process
+is_a: GO:0019614 {is_inferred="true"} ! catechol-containing compound catabolic process
 is_a: GO:0046278 {is_inferred="true"} ! 3,4-dihydroxybenzoate metabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 
@@ -19172,6 +19528,7 @@
 id: GO:0019624 ! atrazine catabolic process to isopropylamine
 is_a: GO:0009308 {is_inferred="true"} ! amine metabolic process
 is_a: GO:0019381 {is_inferred="true"} ! atrazine catabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 is_a: GO:1901160 {is_inferred="true"} ! primary amino compound metabolic process
 
 [Term]
@@ -19193,25 +19550,31 @@
 [Term]
 id: GO:0019628 ! urate catabolic process
 is_a: GO:0046415 {is_inferred="true"} ! urate metabolic process
-is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
+is_a: GO:0072523 {is_inferred="true"} ! purine-containing compound catabolic process
 
 [Term]
 id: GO:0019630 ! quinate metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
+is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
 
 [Term]
 id: GO:0019631 ! quinate catabolic process
 is_a: GO:0019630 {is_inferred="true"} ! quinate metabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
+is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
+is_a: GO:1901616 {is_inferred="true"} ! organic hydroxy compound catabolic process
 
 [Term]
 id: GO:0019632 ! shikimate metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
 
 [Term]
 id: GO:0019633 ! shikimate catabolic process
 is_a: GO:0019632 {is_inferred="true"} ! shikimate metabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
+is_a: GO:1901616 {is_inferred="true"} ! organic hydroxy compound catabolic process
 
 [Term]
 id: GO:0019634 ! organic phosphonate metabolic process
@@ -19224,8 +19587,8 @@
 
 [Term]
 id: GO:0019636 ! phosphonoacetate metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
 is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 
 [Term]
 id: GO:0019637 ! organophosphate metabolic process
@@ -19457,19 +19820,21 @@
 
 [Term]
 id: GO:0019757 ! glycosinolate metabolic process
-is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
+is_a: GO:0016143 {is_inferred="true"} ! S-glycoside metabolic process
 is_a: GO:0043436 {is_inferred="true"} ! oxoacid metabolic process
+is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
 
 [Term]
 id: GO:0019758 ! glycosinolate biosynthetic process
+is_a: GO:0016144 {is_inferred="true"} ! S-glycoside biosynthetic process
 is_a: GO:0019757 {is_inferred="true"} ! glycosinolate metabolic process
-is_a: GO:0044272 {is_inferred="true"} ! sulfur compound biosynthetic process
+is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
 
 [Term]
 id: GO:0019759 ! glycosinolate catabolic process
+is_a: GO:0016145 {is_inferred="true"} ! S-glycoside catabolic process
 is_a: GO:0019757 {is_inferred="true"} ! glycosinolate metabolic process
-is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
-is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
+is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
 
 [Term]
 id: GO:0019760 ! glucosinolate metabolic process
@@ -19489,6 +19854,7 @@
 id: GO:0019805 ! quinolinate biosynthetic process
 is_a: GO:0043650 {is_inferred="true"} ! dicarboxylic acid biosynthetic process
 is_a: GO:0046874 {is_inferred="true"} ! quinolinate metabolic process
+is_a: GO:0072525 {is_inferred="true"} ! pyridine-containing compound biosynthetic process
 
 [Term]
 id: GO:0019808 ! polyamine binding
@@ -19495,7 +19861,16 @@
 is_a: GO:0005488 {is_inferred="true"} ! binding
 
 [Term]
+id: GO:0019809 ! spermidine binding
+is_a: GO:0070405 {is_inferred="true"} ! ammonium ion binding
+
+[Term]
+id: GO:0019810 ! putrescine binding
+is_a: GO:0070405 {is_inferred="true"} ! ammonium ion binding
+
+[Term]
 id: GO:0019811 ! cocaine binding
+is_a: GO:0070405 {is_inferred="true"} ! ammonium ion binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
 
@@ -19540,16 +19915,19 @@
 
 [Term]
 id: GO:0019852 ! L-ascorbic acid metabolic process
+is_a: GO:0005996 {is_inferred="true"} ! monosaccharide metabolic process
 is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 
 [Term]
 id: GO:0019853 ! L-ascorbic acid biosynthetic process
 is_a: GO:0019852 {is_inferred="true"} ! L-ascorbic acid metabolic process
+is_a: GO:0046364 {is_inferred="true"} ! monosaccharide biosynthetic process
 is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 
 [Term]
 id: GO:0019854 ! L-ascorbic acid catabolic process
 is_a: GO:0019852 {is_inferred="true"} ! L-ascorbic acid metabolic process
+is_a: GO:0046365 {is_inferred="true"} ! monosaccharide catabolic process
 is_a: GO:0046395 {is_inferred="true"} ! carboxylic acid catabolic process
 
 [Term]
@@ -19586,6 +19964,7 @@
 
 [Term]
 id: GO:0019877 ! diaminopimelate biosynthetic process
+is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 is_a: GO:0043650 {is_inferred="true"} ! dicarboxylic acid biosynthetic process
 is_a: GO:0046451 {is_inferred="true"} ! diaminopimelate metabolic process
 
@@ -20040,10 +20419,18 @@
 is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
 
 [Term]
+id: GO:0022858 ! alanine transmembrane transporter activity
+is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
+
+[Term]
 id: GO:0022885 ! bacteriocin transmembrane transporter activity
 is_a: GO:1904680 {is_inferred="true"} ! peptide transmembrane transporter activity
 
 [Term]
+id: GO:0022889 ! serine transmembrane transporter activity
+is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
+
+[Term]
 id: GO:0022890 ! inorganic cation transmembrane transporter activity
 is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
 
@@ -20296,6 +20683,8 @@
 [Term]
 id: GO:0030170 ! pyridoxal phosphate binding
 is_a: GO:0043168 {is_inferred="true"} ! anion binding
+is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
+is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
 
 [Term]
 id: GO:0030173 ! integral component of Golgi membrane
@@ -20365,15 +20754,18 @@
 is_a: GO:0030167 {is_inferred="true"} ! proteoglycan catabolic process
 is_a: GO:0030201 {is_inferred="true"} ! heparan sulfate proteoglycan metabolic process
 is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
+is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
 
 [Term]
 id: GO:0030201 ! heparan sulfate proteoglycan metabolic process
 is_a: GO:0006029 {is_inferred="true"} ! proteoglycan metabolic process
 is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
+is_a: GO:0043436 {is_inferred="true"} ! oxoacid metabolic process
 
 [Term]
 id: GO:0030202 ! heparin metabolic process
 is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
+is_a: GO:0043436 {is_inferred="true"} ! oxoacid metabolic process
 is_a: GO:1903510 {is_inferred="true"} ! mucopolysaccharide metabolic process
 
 [Term]
@@ -20383,11 +20775,13 @@
 [Term]
 id: GO:0030204 ! chondroitin sulfate metabolic process
 is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
+is_a: GO:0043436 {is_inferred="true"} ! oxoacid metabolic process
 is_a: GO:1903510 {is_inferred="true"} ! mucopolysaccharide metabolic process
 
 [Term]
 id: GO:0030205 ! dermatan sulfate metabolic process
 is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 is_a: GO:1903510 {is_inferred="true"} ! mucopolysaccharide metabolic process
 
 [Term]
@@ -20395,6 +20789,7 @@
 is_a: GO:0006024 {is_inferred="true"} ! glycosaminoglycan biosynthetic process
 is_a: GO:0030204 {is_inferred="true"} ! chondroitin sulfate metabolic process
 is_a: GO:0044272 {is_inferred="true"} ! sulfur compound biosynthetic process
+is_a: GO:0044711 {is_inferred="true"} ! single-organism biosynthetic process
 
 [Term]
 id: GO:0030207 ! chondroitin sulfate catabolic process
@@ -20401,6 +20796,7 @@
 is_a: GO:0006027 {is_inferred="true"} ! glycosaminoglycan catabolic process
 is_a: GO:0030204 {is_inferred="true"} ! chondroitin sulfate metabolic process
 is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
+is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
 
 [Term]
 id: GO:0030208 ! dermatan sulfate biosynthetic process
@@ -20407,6 +20803,7 @@
 is_a: GO:0006024 {is_inferred="true"} ! glycosaminoglycan biosynthetic process
 is_a: GO:0030205 {is_inferred="true"} ! dermatan sulfate metabolic process
 is_a: GO:0044272 {is_inferred="true"} ! sulfur compound biosynthetic process
+is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 
 [Term]
 id: GO:0030209 ! dermatan sulfate catabolic process
@@ -20413,6 +20810,7 @@
 is_a: GO:0006027 {is_inferred="true"} ! glycosaminoglycan catabolic process
 is_a: GO:0030205 {is_inferred="true"} ! dermatan sulfate metabolic process
 is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
+is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 
 [Term]
 id: GO:0030210 ! heparin biosynthetic process
@@ -20419,6 +20817,7 @@
 is_a: GO:0006024 {is_inferred="true"} ! glycosaminoglycan biosynthetic process
 is_a: GO:0030202 {is_inferred="true"} ! heparin metabolic process
 is_a: GO:0044272 {is_inferred="true"} ! sulfur compound biosynthetic process
+is_a: GO:0044711 {is_inferred="true"} ! single-organism biosynthetic process
 
 [Term]
 id: GO:0030211 ! heparin catabolic process
@@ -20425,6 +20824,7 @@
 is_a: GO:0006027 {is_inferred="true"} ! glycosaminoglycan catabolic process
 is_a: GO:0030202 {is_inferred="true"} ! heparin metabolic process
 is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
+is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
 
 [Term]
 id: GO:0030212 ! hyaluronan metabolic process
@@ -20560,12 +20960,14 @@
 
 [Term]
 id: GO:0030328 ! prenylcysteine catabolic process
+is_a: GO:0000098 {is_inferred="true"} ! sulfur amino acid catabolic process
 is_a: GO:0030329 {is_inferred="true"} ! prenylcysteine metabolic process
 is_a: GO:0042219 {is_inferred="true"} ! cellular modified amino acid catabolic process
 
 [Term]
 id: GO:0030329 ! prenylcysteine metabolic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
+is_a: GO:0000096 {is_inferred="true"} ! sulfur amino acid metabolic process
+is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
 
 [Term]
 id: GO:0030334 ! regulation of cell migration
@@ -20612,13 +21014,12 @@
 
 [Term]
 id: GO:0030393 ! fructoselysine metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
 is_a: GO:0030389 {is_inferred="true"} ! fructosamine metabolic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
 
 [Term]
 id: GO:0030394 ! fructoseglycine metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
 is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
 is_a: GO:0030389 {is_inferred="true"} ! fructosamine metabolic process
 
@@ -20640,21 +21041,29 @@
 
 [Term]
 id: GO:0030416 ! methylamine metabolic process
+is_a: GO:0009308 {is_inferred="true"} ! amine metabolic process
 is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
+is_a: GO:1901160 {is_inferred="true"} ! primary amino compound metabolic process
 
 [Term]
 id: GO:0030417 ! nicotianamine metabolic process
+is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
 is_a: GO:0072350 {is_inferred="true"} ! tricarboxylic acid metabolic process
+is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
 
 [Term]
 id: GO:0030418 ! nicotianamine biosynthetic process
+is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
 is_a: GO:0030417 {is_inferred="true"} ! nicotianamine metabolic process
 is_a: GO:0072351 {is_inferred="true"} ! tricarboxylic acid biosynthetic process
+is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
 
 [Term]
 id: GO:0030419 ! nicotianamine catabolic process
 is_a: GO:0030417 {is_inferred="true"} ! nicotianamine metabolic process
+is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
 is_a: GO:0072352 {is_inferred="true"} ! tricarboxylic acid catabolic process
+is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
 
 [Term]
 id: GO:0030426 ! growth cone
@@ -20801,11 +21210,13 @@
 id: GO:0030552 ! cAMP binding
 is_a: GO:0030551 {is_inferred="true"} ! cyclic nucleotide binding
 is_a: GO:0032559 {is_inferred="true"} ! adenyl ribonucleotide binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
 [Term]
 id: GO:0030553 ! cGMP binding
 is_a: GO:0030551 {is_inferred="true"} ! cyclic nucleotide binding
 is_a: GO:0032561 {is_inferred="true"} ! guanyl ribonucleotide binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
 [Term]
 id: GO:0030554 ! adenyl nucleotide binding
@@ -20816,6 +21227,7 @@
 is_a: GO:0006706 {is_inferred="true"} ! steroid catabolic process
 is_a: GO:0008206 {is_inferred="true"} ! bile acid metabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
+is_a: GO:1901616 {is_inferred="true"} ! organic hydroxy compound catabolic process
 
 [Term]
 id: GO:0030574 ! collagen catabolic process
@@ -20845,6 +21257,7 @@
 [Term]
 id: GO:0030632 ! D-alanine biosynthetic process
 is_a: GO:0046436 {is_inferred="true"} ! D-alanine metabolic process
+is_a: GO:0046437 {is_inferred="true"} ! D-amino acid biosynthetic process
 
 [Term]
 id: GO:0030634 ! carbon fixation by acetyl-CoA pathway
@@ -20867,7 +21280,9 @@
 
 [Term]
 id: GO:0030643 ! cellular phosphate ion homeostasis
+is_a: GO:0030320 {is_inferred="true"} ! cellular monovalent inorganic anion homeostasis
 is_a: GO:0055062 {is_inferred="true"} ! phosphate ion homeostasis
+is_a: GO:0072501 {is_inferred="true"} ! cellular divalent inorganic anion homeostasis
 
 [Term]
 id: GO:0030645 ! glucose catabolic process to butyrate
@@ -21522,8 +21937,11 @@
 
 [Term]
 id: GO:0030974 ! thiamine pyrophosphate transport
+is_a: GO:0015695 {is_inferred="true"} ! organic cation transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015748 {is_inferred="true"} ! organophosphate ester transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
+is_a: GO:0045117 {is_inferred="true"} ! azole transport
+is_a: GO:0072348 {is_inferred="true"} ! sulfur compound transport
 
 [Term]
 id: GO:0030975 ! thiamine binding
@@ -21533,11 +21951,15 @@
 
 [Term]
 id: GO:0030976 ! thiamine pyrophosphate binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
+is_a: GO:0043169 {is_inferred="true"} ! cation binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
+is_a: GO:1901681 {is_inferred="true"} ! sulfur compound binding
 
 [Term]
 id: GO:0030977 ! taurine binding
+is_a: GO:0043210 {is_inferred="true"} ! alkanesulfonate binding
 is_a: GO:1901681 {is_inferred="true"} ! sulfur compound binding
 
 [Term]
@@ -21861,6 +22283,7 @@
 [Term]
 id: GO:0031177 ! phosphopantetheine binding
 is_a: GO:0033218 {is_inferred="true"} ! amide binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:0072341 {is_inferred="true"} ! modified amino acid binding
 
 [Term]
@@ -22162,19 +22585,19 @@
 
 [Term]
 id: GO:0031335 ! regulation of sulfur amino acid metabolic process
+is_a: GO:0006521 {is_inferred="true"} ! regulation of cellular amino acid metabolic process
 is_a: GO:0042762 {is_inferred="true"} ! regulation of sulfur metabolic process
-is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
 
 [Term]
 id: GO:0031336 ! negative regulation of sulfur amino acid metabolic process
 is_a: GO:0031335 {is_inferred="true"} ! regulation of sulfur amino acid metabolic process
-is_a: GO:0051172 {is_inferred="true"} ! negative regulation of nitrogen compound metabolic process
+is_a: GO:0045763 {is_inferred="true"} ! negative regulation of cellular amino acid metabolic process
 is_a: GO:0051175 {is_inferred="true"} ! negative regulation of sulfur metabolic process
 
 [Term]
 id: GO:0031337 ! positive regulation of sulfur amino acid metabolic process
 is_a: GO:0031335 {is_inferred="true"} ! regulation of sulfur amino acid metabolic process
-is_a: GO:0051173 {is_inferred="true"} ! positive regulation of nitrogen compound metabolic process
+is_a: GO:0045764 {is_inferred="true"} ! positive regulation of cellular amino acid metabolic process
 is_a: GO:0051176 {is_inferred="true"} ! positive regulation of sulfur metabolic process
 
 [Term]
@@ -22353,19 +22776,23 @@
 [Term]
 id: GO:0031405 ! lipoic acid binding
 is_a: GO:0005504 {is_inferred="true"} ! fatty acid binding
+is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
+is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
+is_a: GO:1901681 {is_inferred="true"} ! sulfur compound binding
 
 [Term]
 id: GO:0031406 ! carboxylic acid binding
 is_a: GO:0043168 {is_inferred="true"} ! anion binding
+is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
 
 [Term]
 id: GO:0031407 ! oxylipin metabolic process
-is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
+is_a: GO:0006631 {is_inferred="true"} ! fatty acid metabolic process
 
 [Term]
 id: GO:0031408 ! oxylipin biosynthetic process
+is_a: GO:0006633 {is_inferred="true"} ! fatty acid biosynthetic process
 is_a: GO:0031407 {is_inferred="true"} ! oxylipin metabolic process
-is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 
 [Term]
 id: GO:0031410 ! cytoplasmic vesicle
@@ -22374,6 +22801,7 @@
 [Term]
 id: GO:0031418 ! L-ascorbic acid binding
 is_a: GO:0031406 {is_inferred="true"} ! carboxylic acid binding
+is_a: GO:0048029 {is_inferred="true"} ! monosaccharide binding
 
 [Term]
 id: GO:0031419 ! cobalamin binding
@@ -22471,6 +22899,7 @@
 id: GO:0031455 ! glycine betaine metabolic process
 is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
 is_a: GO:0006577 {is_inferred="true"} ! amino-acid betaine metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 
 [Term]
 id: GO:0031456 ! glycine betaine biosynthetic process
@@ -22490,6 +22919,7 @@
 
 [Term]
 id: GO:0031460 ! glycine betaine transport
+is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 is_a: GO:0015838 {is_inferred="true"} ! amino-acid betaine transport
 is_a: GO:0072337 {is_inferred="true"} ! modified amino acid transport
 
@@ -22966,9 +23396,14 @@
 [Term]
 id: GO:0031921 ! pyridoxal phosphate transport
 is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
+is_a: GO:0015748 {is_inferred="true"} ! organophosphate ester transport
+is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
+is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
 id: GO:0031922 ! pyridoxamine transport
+is_a: GO:0015695 {is_inferred="true"} ! organic cation transport
+is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
 is_a: GO:0031919 {is_inferred="true"} ! vitamin B6 transport
 
@@ -22985,11 +23420,14 @@
 
 [Term]
 id: GO:0031926 ! pyridoxal phosphate transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:0015605 {is_inferred="true"} ! organophosphate ester transmembrane transporter activity
 is_a: GO:1901618 {is_inferred="true"} ! organic hydroxy compound transmembrane transporter activity
 
 [Term]
 id: GO:0031927 ! pyridoxamine transmembrane transporter activity
+is_a: GO:0008519 {is_inferred="true"} ! ammonium transmembrane transporter activity
+is_a: GO:0015101 {is_inferred="true"} ! organic cation transmembrane transporter activity
 is_a: GO:0031924 {is_inferred="true"} ! vitamin B6 transporter activity
 is_a: GO:0090482 {is_inferred="true"} ! vitamin transmembrane transporter activity
 is_a: GO:1901618 {is_inferred="true"} ! organic hydroxy compound transmembrane transporter activity
@@ -23629,7 +24067,7 @@
 
 [Term]
 id: GO:0032218 ! riboflavin transport
-is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
@@ -23867,7 +24305,7 @@
 
 [Term]
 id: GO:0032309 ! icosanoid secretion
-is_a: GO:0046903 {is_inferred="true"} ! secretion
+is_a: GO:0046717 {is_inferred="true"} ! acid secretion
 is_a: GO:0071715 {is_inferred="true"} ! icosanoid transport
 
 [Term]
@@ -23884,6 +24322,9 @@
 id: GO:0032323 ! lipoate catabolic process
 is_a: GO:0009062 {is_inferred="true"} ! fatty acid catabolic process
 is_a: GO:0009106 {is_inferred="true"} ! lipoate metabolic process
+is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
+is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
+is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
 
 [Term]
 id: GO:0032324 ! molybdopterin cofactor biosynthetic process
@@ -23915,9 +24356,13 @@
 
 [Term]
 id: GO:0032328 ! alanine transport
-is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
 
 [Term]
+id: GO:0032329 ! serine transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
+
+[Term]
 id: GO:0032330 ! regulation of chondrocyte differentiation
 is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
 is_a: GO:0061035 {is_inferred="true"} ! regulation of cartilage development
@@ -24054,8 +24499,12 @@
 
 [Term]
 id: GO:0032361 ! pyridoxal phosphate catabolic process
+is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
 is_a: GO:0042822 {is_inferred="true"} ! pyridoxal phosphate metabolic process
-is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
+is_a: GO:0046185 {is_inferred="true"} ! aldehyde catabolic process
+is_a: GO:0046434 {is_inferred="true"} ! organophosphate catabolic process
+is_a: GO:0072526 {is_inferred="true"} ! pyridine-containing compound catabolic process
+is_a: GO:1901616 {is_inferred="true"} ! organic hydroxy compound catabolic process
 
 [Term]
 id: GO:0032363 ! FMN catabolic process
@@ -24576,6 +25025,7 @@
 id: GO:0032560 ! guanyl deoxyribonucleotide binding
 is_a: GO:0019001 {is_inferred="true"} ! guanyl nucleotide binding
 is_a: GO:0032554 {is_inferred="true"} ! purine deoxyribonucleotide binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
 [Term]
 id: GO:0032561 ! guanyl ribonucleotide binding
@@ -24585,14 +25035,17 @@
 [Term]
 id: GO:0032562 ! dAMP binding
 is_a: GO:0032558 {is_inferred="true"} ! adenyl deoxyribonucleotide binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
 [Term]
 id: GO:0032563 ! dADP binding
 is_a: GO:0032558 {is_inferred="true"} ! adenyl deoxyribonucleotide binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
 [Term]
 id: GO:0032564 ! dATP binding
 is_a: GO:0032558 {is_inferred="true"} ! adenyl deoxyribonucleotide binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
 [Term]
 id: GO:0032565 ! dGMP binding
@@ -25284,8 +25737,7 @@
 
 [Term]
 id: GO:0032782 ! bile acid secretion
-is_a: GO:0006869 {is_inferred="true"} ! lipid transport
-is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
+is_a: GO:0015721 {is_inferred="true"} ! bile acid and bile salt transport
 
 [Term]
 id: GO:0032784 ! regulation of DNA-templated transcription, elongation
@@ -25307,7 +25759,7 @@
 
 [Term]
 id: GO:0032788 ! saturated monocarboxylic acid metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 
 [Term]
 id: GO:0032790 ! ribosome disassembly
@@ -25651,15 +26103,18 @@
 
 [Term]
 id: GO:0032893 ! regulation of gluconate transport
+is_a: GO:0032890 {is_inferred="true"} ! regulation of organic acid transport
 is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
 
 [Term]
 id: GO:0032894 ! negative regulation of gluconate transport
+is_a: GO:0032891 {is_inferred="true"} ! negative regulation of organic acid transport
 is_a: GO:0032893 {is_inferred="true"} ! regulation of gluconate transport
 is_a: GO:1903792 {is_inferred="true"} ! negative regulation of anion transport
 
 [Term]
 id: GO:0032895 ! positive regulation of gluconate transport
+is_a: GO:0032892 {is_inferred="true"} ! positive regulation of organic acid transport
 is_a: GO:0032893 {is_inferred="true"} ! regulation of gluconate transport
 is_a: GO:1903793 {is_inferred="true"} ! positive regulation of anion transport
 
@@ -26157,11 +26612,19 @@
 [Term]
 id: GO:0033049 ! clavulanic acid metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0043603 {is_inferred="true"} ! cellular amide metabolic process
+is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
+is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
+is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
 
 [Term]
 id: GO:0033050 ! clavulanic acid biosynthetic process
+is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
 is_a: GO:0033049 {is_inferred="true"} ! clavulanic acid metabolic process
+is_a: GO:0043604 {is_inferred="true"} ! amide biosynthetic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
+is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
+is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
 
 [Term]
 id: GO:0033051 ! aminophosphonate metabolic process
@@ -26170,18 +26633,31 @@
 
 [Term]
 id: GO:0033052 ! cyanoamino acid metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
 is_a: GO:0050898 {is_inferred="true"} ! nitrile metabolic process
 
 [Term]
 id: GO:0033053 ! D-glutamine metabolic process
 is_a: GO:0006541 {is_inferred="true"} ! glutamine metabolic process
+is_a: GO:0046416 {is_inferred="true"} ! D-amino acid metabolic process
 
 [Term]
 id: GO:0033054 ! D-glutamate metabolic process
 is_a: GO:0006536 {is_inferred="true"} ! glutamate metabolic process
+is_a: GO:0046416 {is_inferred="true"} ! D-amino acid metabolic process
 
 [Term]
+id: GO:0033055 ! D-arginine metabolic process
+is_a: GO:0006525 {is_inferred="true"} ! arginine metabolic process
+is_a: GO:0046416 {is_inferred="true"} ! D-amino acid metabolic process
+
+[Term]
+id: GO:0033056 ! D-ornithine metabolic process
+is_a: GO:0006591 {is_inferred="true"} ! ornithine metabolic process
+is_a: GO:0046416 {is_inferred="true"} ! D-amino acid metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
+
+[Term]
 id: GO:0033067 ! macrolide metabolic process
 is_a: GO:0030638 {is_inferred="true"} ! polyketide metabolic process
 is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
@@ -26585,8 +27061,13 @@
 [Term]
 id: GO:0033229 ! cysteine transmembrane transporter activity
 is_a: GO:0000099 {is_inferred="true"} ! sulfur amino acid transmembrane transporter activity
+is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
 
 [Term]
+id: GO:0033230 ! cysteine-transporting ATPase activity
+is_a: GO:0019829 {is_inferred="true"} ! cation-transporting ATPase activity
+
+[Term]
 id: GO:0033231 ! carbohydrate export
 is_a: GO:0008643 {is_inferred="true"} ! carbohydrate transport
 
@@ -26703,6 +27184,7 @@
 
 [Term]
 id: GO:0033271 ! myo-inositol phosphate transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015748 {is_inferred="true"} ! organophosphate ester transport
 is_a: GO:0015791 {is_inferred="true"} ! polyol transport
 
@@ -26740,13 +27222,13 @@
 
 [Term]
 id: GO:0033294 ! ectoine binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
+is_a: GO:0033293 {is_inferred="true"} ! monocarboxylic acid binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
 
 [Term]
 id: GO:0033295 ! hydroxyectoine binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
+is_a: GO:0033293 {is_inferred="true"} ! monocarboxylic acid binding
 is_a: GO:0043178 {is_inferred="true"} ! alcohol binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
@@ -26788,7 +27270,7 @@
 
 [Term]
 id: GO:0033308 ! hydroxyectoine transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
+is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
 is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
 is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
@@ -26831,6 +27313,7 @@
 
 [Term]
 id: GO:0033319 ! UDP-D-xylose metabolic process
+is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
 is_a: GO:0009225 {is_inferred="true"} ! nucleotide-sugar metabolic process
 
 [Term]
@@ -26840,12 +27323,14 @@
 
 [Term]
 id: GO:0033321 ! homomethionine metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
+is_a: GO:0000096 {is_inferred="true"} ! sulfur amino acid metabolic process
+is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
 
 [Term]
 id: GO:0033322 ! homomethionine biosynthetic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
+is_a: GO:0000097 {is_inferred="true"} ! sulfur amino acid biosynthetic process
 is_a: GO:0033321 {is_inferred="true"} ! homomethionine metabolic process
+is_a: GO:1901607 {is_inferred="true"} ! alpha-amino acid biosynthetic process
 
 [Term]
 id: GO:0033323 ! choline biosynthetic process via CDP-choline
@@ -26930,6 +27415,7 @@
 
 [Term]
 id: GO:0033351 ! UDP-D-apiose metabolic process
+is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
 is_a: GO:0009225 {is_inferred="true"} ! nucleotide-sugar metabolic process
 
 [Term]
@@ -26939,9 +27425,8 @@
 
 [Term]
 id: GO:0033353 ! S-adenosylmethionine cycle
-is_a: GO:0000096 {is_inferred="true"} ! sulfur amino acid metabolic process
-is_a: GO:0009066 {is_inferred="true"} ! aspartate family amino acid metabolic process
-is_a: GO:0009069 {is_inferred="true"} ! serine family amino acid metabolic process
+is_a: GO:0006555 {is_inferred="true"} ! methionine metabolic process
+is_a: GO:0046439 {is_inferred="true"} ! L-cysteine metabolic process
 is_a: GO:0046498 {is_inferred="true"} ! S-adenosylhomocysteine metabolic process
 
 [Term]
@@ -26950,6 +27435,7 @@
 
 [Term]
 id: GO:0033356 ! UDP-L-arabinose metabolic process
+is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
 is_a: GO:0009225 {is_inferred="true"} ! nucleotide-sugar metabolic process
 
 [Term]
@@ -27074,6 +27560,7 @@
 
 [Term]
 id: GO:0033467 ! CMP-keto-3-deoxy-D-manno-octulosonic acid metabolic process
+is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
 is_a: GO:0009225 {is_inferred="true"} ! nucleotide-sugar metabolic process
 
 [Term]
@@ -27083,15 +27570,18 @@
 
 [Term]
 id: GO:0033469 ! gibberellin 12 metabolic process
+is_a: GO:0009685 {is_inferred="true"} ! gibberellin metabolic process
 is_a: GO:0043648 {is_inferred="true"} ! dicarboxylic acid metabolic process
 
 [Term]
 id: GO:0033470 ! gibberellin 12 biosynthetic process
+is_a: GO:0009686 {is_inferred="true"} ! gibberellin biosynthetic process
 is_a: GO:0033469 {is_inferred="true"} ! gibberellin 12 metabolic process
 is_a: GO:0043650 {is_inferred="true"} ! dicarboxylic acid biosynthetic process
 
 [Term]
 id: GO:0033471 ! GDP-L-galactose metabolic process
+is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
 is_a: GO:0009225 {is_inferred="true"} ! nucleotide-sugar metabolic process
 
 [Term]
@@ -27109,15 +27599,17 @@
 
 [Term]
 id: GO:0033477 ! S-methylmethionine metabolic process
+is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
 is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
 
 [Term]
 id: GO:0033478 ! UDP-rhamnose metabolic process
 is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
+is_a: GO:0009225 {is_inferred="true"} ! nucleotide-sugar metabolic process
 
 [Term]
 id: GO:0033479 ! UDP-D-galacturonate metabolic process
+is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
 is_a: GO:0009225 {is_inferred="true"} ! nucleotide-sugar metabolic process
 
 [Term]
@@ -27128,6 +27620,7 @@
 [Term]
 id: GO:0033481 ! galacturonate biosynthetic process
 is_a: GO:0019586 {is_inferred="true"} ! galacturonate metabolic process
+is_a: GO:0046364 {is_inferred="true"} ! monosaccharide biosynthetic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 
 [Term]
@@ -27180,21 +27673,32 @@
 
 [Term]
 id: GO:0033494 ! ferulate metabolic process
+is_a: GO:0018904 {is_inferred="true"} ! ether metabolic process
+is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 
 [Term]
 id: GO:0033495 ! ferulate biosynthetic process
 is_a: GO:0033494 {is_inferred="true"} ! ferulate metabolic process
+is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
+is_a: GO:1901503 {is_inferred="true"} ! ether biosynthetic process
 
 [Term]
 id: GO:0033496 ! sinapate metabolic process
+is_a: GO:0009698 {is_inferred="true"} ! phenylpropanoid metabolic process
+is_a: GO:0018904 {is_inferred="true"} ! ether metabolic process
+is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 
 [Term]
 id: GO:0033497 ! sinapate biosynthetic process
+is_a: GO:0009699 {is_inferred="true"} ! phenylpropanoid biosynthetic process
 is_a: GO:0033496 {is_inferred="true"} ! sinapate metabolic process
+is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
+is_a: GO:1901503 {is_inferred="true"} ! ether biosynthetic process
 
 [Term]
 id: GO:0033498 ! galactose catabolic process via D-galactonate
@@ -27228,8 +27732,9 @@
 
 [Term]
 id: GO:0033507 ! glucosinolate biosynthetic process from phenylalanine
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
+is_a: GO:0009072 {is_inferred="true"} ! aromatic amino acid family metabolic process
 is_a: GO:0019761 {is_inferred="true"} ! glucosinolate biosynthetic process
+is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
 
 [Term]
 id: GO:0033508 ! glutamate catabolic process to butyrate
@@ -27388,6 +27893,7 @@
 id: GO:0033587 ! shikimate biosynthetic process
 is_a: GO:0019632 {is_inferred="true"} ! shikimate metabolic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
+is_a: GO:1901617 {is_inferred="true"} ! organic hydroxy compound biosynthetic process
 
 [Term]
 id: GO:0033590 ! response to cobalamin
@@ -27431,11 +27937,13 @@
 id: GO:0033602 ! negative regulation of dopamine secretion
 is_a: GO:0014059 {is_inferred="true"} ! regulation of dopamine secretion
 is_a: GO:0033604 {is_inferred="true"} ! negative regulation of catecholamine secretion
+is_a: GO:0043271 {is_inferred="true"} ! negative regulation of ion transport
 
 [Term]
 id: GO:0033603 ! positive regulation of dopamine secretion
 is_a: GO:0014059 {is_inferred="true"} ! regulation of dopamine secretion
 is_a: GO:0033605 {is_inferred="true"} ! positive regulation of catecholamine secretion
+is_a: GO:0043270 {is_inferred="true"} ! positive regulation of ion transport
 
 [Term]
 id: GO:0033604 ! negative regulation of catecholamine secretion
@@ -28171,8 +28679,7 @@
 
 [Term]
 id: GO:0034201 ! response to oleic acid
-is_a: GO:0033993 {is_inferred="true"} ! response to lipid
-is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
+is_a: GO:0070542 {is_inferred="true"} ! response to fatty acid
 
 [Term]
 id: GO:0034203 ! glycolipid translocation
@@ -28183,6 +28690,7 @@
 id: GO:0034213 ! quinolinate catabolic process
 is_a: GO:0043649 {is_inferred="true"} ! dicarboxylic acid catabolic process
 is_a: GO:0046874 {is_inferred="true"} ! quinolinate metabolic process
+is_a: GO:0072526 {is_inferred="true"} ! pyridine-containing compound catabolic process
 
 [Term]
 id: GO:0034217 ! ascospore wall chitin biosynthetic process
@@ -28217,15 +28725,20 @@
 
 [Term]
 id: GO:0034226 ! lysine import
+is_a: GO:0015819 {is_inferred="true"} ! lysine transport
 is_a: GO:0043090 {is_inferred="true"} ! amino acid import
 
 [Term]
 id: GO:0034228 ! ethanolamine transmembrane transporter activity
 is_a: GO:0005275 {is_inferred="true"} ! amine transmembrane transporter activity
+is_a: GO:0008519 {is_inferred="true"} ! ammonium transmembrane transporter activity
+is_a: GO:0015101 {is_inferred="true"} ! organic cation transmembrane transporter activity
 is_a: GO:0015665 {is_inferred="true"} ! alcohol transmembrane transporter activity
 
 [Term]
 id: GO:0034229 ! ethanolamine transport
+is_a: GO:0015695 {is_inferred="true"} ! organic cation transport
+is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 is_a: GO:0015837 {is_inferred="true"} ! amine transport
 is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
 
@@ -28357,26 +28870,37 @@
 
 [Term]
 id: GO:0034267 ! discadenine metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
+is_a: GO:0072521 {is_inferred="true"} ! purine-containing compound metabolic process
+is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
 
 [Term]
 id: GO:0034268 ! discadenine biosynthetic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 is_a: GO:0034267 {is_inferred="true"} ! discadenine metabolic process
+is_a: GO:0072522 {is_inferred="true"} ! purine-containing compound biosynthetic process
+is_a: GO:1901607 {is_inferred="true"} ! alpha-amino acid biosynthetic process
 
 [Term]
 id: GO:0034269 ! discadenine catabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
 is_a: GO:0034267 {is_inferred="true"} ! discadenine metabolic process
+is_a: GO:0072523 {is_inferred="true"} ! purine-containing compound catabolic process
+is_a: GO:1901606 {is_inferred="true"} ! alpha-amino acid catabolic process
 
 [Term]
 id: GO:0034275 ! kynurenic acid metabolic process
+is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
+is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
+is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
 
 [Term]
 id: GO:0034276 ! kynurenic acid biosynthetic process
+is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
+is_a: GO:0019438 {is_inferred="true"} ! aromatic compound biosynthetic process
 is_a: GO:0034275 {is_inferred="true"} ! kynurenic acid metabolic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
+is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
+is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
 
 [Term]
 id: GO:0034284 ! response to monosaccharide
@@ -28574,7 +29098,7 @@
 [Term]
 id: GO:0034418 ! urate biosynthetic process
 is_a: GO:0046415 {is_inferred="true"} ! urate metabolic process
-is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
+is_a: GO:0072522 {is_inferred="true"} ! purine-containing compound biosynthetic process
 
 [Term]
 id: GO:0034424 ! Vps55/Vps68 complex
@@ -28742,6 +29266,7 @@
 [Term]
 id: GO:0034618 ! arginine binding
 is_a: GO:0016597 {is_inferred="true"} ! amino acid binding
+is_a: GO:0043169 {is_inferred="true"} ! cation binding
 
 [Term]
 id: GO:0034624 ! DNA recombinase assembly involved in gene conversion at mating-type locus
@@ -28763,6 +29288,7 @@
 
 [Term]
 id: GO:0034634 ! glutathione transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:0035673 {is_inferred="true"} ! oligopeptide transmembrane transporter activity
 is_a: GO:0042937 {is_inferred="true"} ! tripeptide transporter activity
 is_a: GO:1901682 {is_inferred="true"} ! sulfur compound transmembrane transporter activity
@@ -28769,6 +29295,7 @@
 
 [Term]
 id: GO:0034635 ! glutathione transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0042939 {is_inferred="true"} ! tripeptide transport
 is_a: GO:0072337 {is_inferred="true"} ! modified amino acid transport
 is_a: GO:0072348 {is_inferred="true"} ! sulfur compound transport
@@ -28838,6 +29365,8 @@
 [Term]
 id: GO:0034659 ! isopropylmalate transport
 is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
+is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
+is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
 
 [Term]
 id: GO:0034662 ! CFTR-NHERF-ezrin complex
@@ -28857,6 +29386,10 @@
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
 [Term]
+id: GO:0034694 ! response to prostaglandin
+is_a: GO:0070542 {is_inferred="true"} ! response to fatty acid
+
+[Term]
 id: GO:0034695 ! response to prostaglandin E
 is_a: GO:0034694 {is_inferred="true"} ! response to prostaglandin
 is_a: GO:1901654 {is_inferred="true"} ! response to ketone
@@ -28965,11 +29498,13 @@
 id: GO:0034775 ! glutathione transmembrane transport
 is_a: GO:0034635 {is_inferred="true"} ! glutathione transport
 is_a: GO:0035443 {is_inferred="true"} ! tripeptide transmembrane transport
+is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
 id: GO:0034776 ! response to histamine
 is_a: GO:0010243 {is_inferred="true"} ! response to organonitrogen compound
 is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
+is_a: GO:0060359 {is_inferred="true"} ! response to ammonium ion
 
 [Term]
 id: GO:0034982 ! mitochondrial protein processing
@@ -29257,6 +29792,7 @@
 
 [Term]
 id: GO:0035240 ! dopamine binding
+is_a: GO:0070405 {is_inferred="true"} ! ammonium ion binding
 is_a: GO:1901338 {is_inferred="true"} ! catecholamine binding
 
 [Term]
@@ -29290,6 +29826,7 @@
 
 [Term]
 id: GO:0035276 ! ethanol binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:0043178 {is_inferred="true"} ! alcohol binding
 
 [Term]
@@ -29389,16 +29926,18 @@
 [Term]
 id: GO:0035348 ! acetyl-CoA transmembrane transport
 is_a: GO:0015876 {is_inferred="true"} ! acetyl-CoA transport
-is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
+is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
 id: GO:0035349 ! coenzyme A transmembrane transport
 is_a: GO:0015880 {is_inferred="true"} ! coenzyme A transport
 is_a: GO:0071106 {is_inferred="true"} ! adenosine 3',5'-bisphosphate transmembrane transport
+is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
 id: GO:0035350 ! FAD transmembrane transport
 is_a: GO:0015883 {is_inferred="true"} ! FAD transport
+is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 is_a: GO:1901679 {is_inferred="true"} ! nucleotide transmembrane transport
 
 [Term]
@@ -29462,6 +30001,7 @@
 [Term]
 id: GO:0035373 ! chondroitin sulfate proteoglycan binding
 is_a: GO:0005539 {is_inferred="true"} ! glycosaminoglycan binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:0043394 {is_inferred="true"} ! proteoglycan binding
 is_a: GO:1901681 {is_inferred="true"} ! sulfur compound binding
 
@@ -29468,6 +30008,7 @@
 [Term]
 id: GO:0035374 ! chondroitin sulfate binding
 is_a: GO:0005539 {is_inferred="true"} ! glycosaminoglycan binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:1901681 {is_inferred="true"} ! sulfur compound binding
 
 [Term]
@@ -29566,7 +30107,8 @@
 [Term]
 id: GO:0035429 ! gluconate transmembrane transport
 is_a: GO:0015725 {is_inferred="true"} ! gluconate transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:0034219 {is_inferred="true"} ! carbohydrate transmembrane transport
+is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
 id: GO:0035430 ! regulation of gluconate transmembrane transport
@@ -29588,7 +30130,7 @@
 [Term]
 id: GO:0035433 ! acetate transmembrane transport
 is_a: GO:0006846 {is_inferred="true"} ! acetate transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
 id: GO:0035434 ! copper ion transmembrane transport
@@ -29608,6 +30150,7 @@
 id: GO:0035438 ! cyclic-di-GMP binding
 is_a: GO:0030551 {is_inferred="true"} ! cyclic nucleotide binding
 is_a: GO:0032561 {is_inferred="true"} ! guanyl ribonucleotide binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
 [Term]
 id: GO:0035440 ! tuberculosinol biosynthetic process
@@ -29709,11 +30252,15 @@
 [Term]
 id: GO:0035498 ! carnosine metabolic process
 is_a: GO:0006518 {is_inferred="true"} ! peptide metabolic process
+is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
+is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 
 [Term]
 id: GO:0035499 ! carnosine biosynthetic process
 is_a: GO:0035498 {is_inferred="true"} ! carnosine metabolic process
+is_a: GO:0042398 {is_inferred="true"} ! cellular modified amino acid biosynthetic process
 is_a: GO:0043043 {is_inferred="true"} ! peptide biosynthetic process
+is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 
 [Term]
 id: GO:0035504 ! regulation of myosin light chain kinase activity
@@ -29744,6 +30291,8 @@
 [Term]
 id: GO:0035524 ! proline transmembrane transport
 is_a: GO:0003333 {is_inferred="true"} ! amino acid transmembrane transport
+is_a: GO:0015824 {is_inferred="true"} ! proline transport
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 
 [Term]
 id: GO:0035528 ! UDP-N-acetylglucosamine biosynthesis involved in chitin biosynthesis
@@ -29916,6 +30465,7 @@
 
 [Term]
 id: GO:0035639 ! purine ribonucleoside triphosphate binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:1901265 {is_inferred="true"} ! nucleoside phosphate binding
 
 [Term]
@@ -29937,6 +30487,7 @@
 
 [Term]
 id: GO:0035674 ! tricarboxylic acid transmembrane transport
+is_a: GO:0006842 {is_inferred="true"} ! tricarboxylic acid transport
 is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
@@ -30137,6 +30688,7 @@
 [Term]
 id: GO:0035832 ! berbamunine metabolic process
 is_a: GO:0046445 {is_inferred="true"} ! benzyl isoquinoline alkaloid metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 
 [Term]
 id: GO:0035833 ! berbamunine biosynthetic process
@@ -30219,7 +30771,7 @@
 [Term]
 id: GO:0035873 ! lactate transmembrane transport
 is_a: GO:0015727 {is_inferred="true"} ! lactate transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
 id: GO:0035883 ! enteroendocrine cell differentiation
@@ -30508,6 +31060,7 @@
 
 [Term]
 id: GO:0036088 ! D-serine catabolic process
+is_a: GO:0019478 {is_inferred="true"} ! D-amino acid catabolic process
 is_a: GO:0070178 {is_inferred="true"} ! D-serine metabolic process
 
 [Term]
@@ -30530,20 +31083,19 @@
 id: GO:0036100 ! leukotriene catabolic process
 is_a: GO:0006691 {is_inferred="true"} ! leukotriene metabolic process
 is_a: GO:0009062 {is_inferred="true"} ! fatty acid catabolic process
+is_a: GO:1901523 {is_inferred="true"} ! icosanoid catabolic process
 
 [Term]
 id: GO:0036101 ! leukotriene B4 catabolic process
-is_a: GO:0016042 {is_inferred="true"} ! lipid catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
+is_a: GO:0036100 {is_inferred="true"} ! leukotriene catabolic process
 is_a: GO:0036102 {is_inferred="true"} ! leukotriene B4 metabolic process
-is_a: GO:1901523 {is_inferred="true"} ! icosanoid catabolic process
+is_a: GO:0042758 {is_inferred="true"} ! long-chain fatty acid catabolic process
 is_a: GO:1901616 {is_inferred="true"} ! organic hydroxy compound catabolic process
 
 [Term]
 id: GO:0036102 ! leukotriene B4 metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
-is_a: GO:0006629 {is_inferred="true"} ! lipid metabolic process
-is_a: GO:1901568 {is_inferred="true"} ! fatty acid derivative metabolic process
+is_a: GO:0001676 {is_inferred="true"} ! long-chain fatty acid metabolic process
+is_a: GO:0006691 {is_inferred="true"} ! leukotriene metabolic process
 is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
 
 [Term]
@@ -30550,6 +31102,7 @@
 id: GO:0036103 ! Kdo2-lipid A metabolic process
 is_a: GO:0006644 {is_inferred="true"} ! phospholipid metabolic process
 is_a: GO:0006664 {is_inferred="true"} ! glycolipid metabolic process
+is_a: GO:0043648 {is_inferred="true"} ! dicarboxylic acid metabolic process
 is_a: GO:1901269 {is_inferred="true"} ! lipooligosaccharide metabolic process
 
 [Term]
@@ -30557,6 +31110,7 @@
 is_a: GO:0008654 {is_inferred="true"} ! phospholipid biosynthetic process
 is_a: GO:0009247 {is_inferred="true"} ! glycolipid biosynthetic process
 is_a: GO:0036103 {is_inferred="true"} ! Kdo2-lipid A metabolic process
+is_a: GO:0043650 {is_inferred="true"} ! dicarboxylic acid biosynthetic process
 is_a: GO:1901271 {is_inferred="true"} ! lipooligosaccharide biosynthetic process
 
 [Term]
@@ -30575,6 +31129,7 @@
 [Term]
 id: GO:0036109 ! alpha-linolenic acid metabolic process
 is_a: GO:0001676 {is_inferred="true"} ! long-chain fatty acid metabolic process
+is_a: GO:0033559 {is_inferred="true"} ! unsaturated fatty acid metabolic process
 
 [Term]
 id: GO:0036111 ! very long-chain fatty-acyl-CoA metabolic process
@@ -30611,7 +31166,7 @@
 
 [Term]
 id: GO:0036127 ! 3-sulfino-L-alanine binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
+is_a: GO:0016597 {is_inferred="true"} ! amino acid binding
 is_a: GO:0072341 {is_inferred="true"} ! modified amino acid binding
 is_a: GO:1901681 {is_inferred="true"} ! sulfur compound binding
 
@@ -30667,10 +31222,12 @@
 
 [Term]
 id: GO:0036229 ! L-glutamine import
+is_a: GO:0006868 {is_inferred="true"} ! glutamine transport
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 
 [Term]
 id: GO:0036231 ! L-threonine import
+is_a: GO:0015826 {is_inferred="true"} ! threonine transport
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 
 [Term]
@@ -30680,11 +31237,13 @@
 
 [Term]
 id: GO:0036233 ! glycine import
+is_a: GO:0015816 {is_inferred="true"} ! glycine transport
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 
 [Term]
 id: GO:0036241 ! glutamate catabolic process to 4-hydroxybutyrate
-is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0006631 {is_inferred="true"} ! fatty acid metabolic process
+is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
 
 [Term]
 id: GO:0036245 ! cellular response to menadione
@@ -30728,10 +31287,12 @@
 [Term]
 id: GO:0036255 ! response to methylamine
 is_a: GO:0014075 {is_inferred="true"} ! response to amine
+is_a: GO:0060359 {is_inferred="true"} ! response to ammonium ion
 
 [Term]
 id: GO:0036256 ! cellular response to methylamine
 is_a: GO:0036255 {is_inferred="true"} ! response to methylamine
+is_a: GO:0071242 {is_inferred="true"} ! cellular response to ammonium ion
 is_a: GO:0071418 {is_inferred="true"} ! cellular response to amine stimulus
 
 [Term]
@@ -30748,7 +31309,7 @@
 
 [Term]
 id: GO:0036271 ! response to methylphenidate
-is_a: GO:0042221 {is_inferred="true"} ! response to chemical
+is_a: GO:0060359 {is_inferred="true"} ! response to ammonium ion
 
 [Term]
 id: GO:0036272 ! response to gemcitabine
@@ -31343,7 +31904,7 @@
 
 [Term]
 id: GO:0042049 ! cellular acyl-CoA homeostasis
-is_a: GO:0055082 {is_inferred="true"} ! cellular chemical homeostasis
+is_a: GO:0030002 {is_inferred="true"} ! cellular anion homeostasis
 
 [Term]
 id: GO:0042053 ! regulation of dopamine metabolic process
@@ -31612,6 +32173,8 @@
 id: GO:0042194 ! quinate biosynthetic process
 is_a: GO:0019630 {is_inferred="true"} ! quinate metabolic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
+is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
+is_a: GO:1901617 {is_inferred="true"} ! organic hydroxy compound biosynthetic process
 
 [Term]
 id: GO:0042196 ! chlorinated hydrocarbon metabolic process
@@ -31717,13 +32280,15 @@
 
 [Term]
 id: GO:0042217 ! 1-aminocyclopropane-1-carboxylate catabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
 is_a: GO:0018871 {is_inferred="true"} ! 1-aminocyclopropane-1-carboxylate metabolic process
+is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
+is_a: GO:1901606 {is_inferred="true"} ! alpha-amino acid catabolic process
 
 [Term]
 id: GO:0042218 ! 1-aminocyclopropane-1-carboxylate biosynthetic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 is_a: GO:0018871 {is_inferred="true"} ! 1-aminocyclopropane-1-carboxylate metabolic process
+is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
+is_a: GO:1901607 {is_inferred="true"} ! alpha-amino acid biosynthetic process
 
 [Term]
 id: GO:0042219 ! cellular modified amino acid catabolic process
@@ -31733,6 +32298,7 @@
 id: GO:0042220 ! response to cocaine
 is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
 is_a: GO:0043279 {is_inferred="true"} ! response to alkaloid
+is_a: GO:0060359 {is_inferred="true"} ! response to ammonium ion
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
 [Term]
@@ -31885,23 +32451,23 @@
 
 [Term]
 id: GO:0042316 ! penicillin metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
 is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
 is_a: GO:0030653 {is_inferred="true"} ! beta-lactam antibiotic metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 
 [Term]
 id: GO:0042317 ! penicillin catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
 is_a: GO:0030655 {is_inferred="true"} ! beta-lactam antibiotic catabolic process
 is_a: GO:0042316 {is_inferred="true"} ! penicillin metabolic process
 is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
+is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 
 [Term]
 id: GO:0042318 ! penicillin biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0030654 {is_inferred="true"} ! beta-lactam antibiotic biosynthetic process
 is_a: GO:0042316 {is_inferred="true"} ! penicillin metabolic process
 is_a: GO:0044272 {is_inferred="true"} ! sulfur compound biosynthetic process
+is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 
 [Term]
 id: GO:0042320 ! regulation of circadian sleep/wake cycle, REM sleep
@@ -31939,6 +32505,7 @@
 [Term]
 id: GO:0042339 ! keratan sulfate metabolic process
 is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
+is_a: GO:0043436 {is_inferred="true"} ! oxoacid metabolic process
 is_a: GO:1903510 {is_inferred="true"} ! mucopolysaccharide metabolic process
 
 [Term]
@@ -31946,6 +32513,7 @@
 is_a: GO:0006027 {is_inferred="true"} ! glycosaminoglycan catabolic process
 is_a: GO:0042339 {is_inferred="true"} ! keratan sulfate metabolic process
 is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
+is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
 
 [Term]
 id: GO:0042341 ! cyanogenic glycoside metabolic process
@@ -31961,12 +32529,12 @@
 
 [Term]
 id: GO:0042343 ! indole glucosinolate metabolic process
-is_a: GO:0016143 {is_inferred="true"} ! S-glycoside metabolic process
+is_a: GO:0019760 {is_inferred="true"} ! glucosinolate metabolic process
 is_a: GO:0042430 {is_inferred="true"} ! indole-containing compound metabolic process
 
 [Term]
 id: GO:0042344 ! indole glucosinolate catabolic process
-is_a: GO:0016145 {is_inferred="true"} ! S-glycoside catabolic process
+is_a: GO:0019762 {is_inferred="true"} ! glucosinolate catabolic process
 is_a: GO:0042343 {is_inferred="true"} ! indole glucosinolate metabolic process
 is_a: GO:0042436 {is_inferred="true"} ! indole-containing compound catabolic process
 
@@ -32013,6 +32581,7 @@
 [Term]
 id: GO:0042357 ! thiamine diphosphate metabolic process
 is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
+is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
 is_a: GO:0006796 {is_inferred="true"} ! phosphate-containing compound metabolic process
 is_a: GO:0019637 {is_inferred="true"} ! organophosphate metabolic process
 is_a: GO:0072527 {is_inferred="true"} ! pyrimidine-containing compound metabolic process
@@ -32021,6 +32590,7 @@
 id: GO:0042358 ! thiamine diphosphate catabolic process
 is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
 is_a: GO:0042357 {is_inferred="true"} ! thiamine diphosphate metabolic process
+is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
 is_a: GO:0046434 {is_inferred="true"} ! organophosphate catabolic process
 is_a: GO:0072529 {is_inferred="true"} ! pyrimidine-containing compound catabolic process
 
@@ -32049,7 +32619,11 @@
 [Term]
 id: GO:0042367 ! biotin catabolic process
 is_a: GO:0006768 {is_inferred="true"} ! biotin metabolic process
+is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
+is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
+is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
+is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
 
 [Term]
 id: GO:0042368 ! vitamin D biosynthetic process
@@ -32109,7 +32683,7 @@
 
 [Term]
 id: GO:0042399 ! ectoine metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
 is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
 is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
@@ -32116,9 +32690,9 @@
 
 [Term]
 id: GO:0042400 ! ectoine catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
 is_a: GO:0042399 {is_inferred="true"} ! ectoine metabolic process
 is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
+is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
 is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
 
@@ -32131,6 +32705,7 @@
 id: GO:0042412 ! taurine biosynthetic process
 is_a: GO:0019530 {is_inferred="true"} ! taurine metabolic process
 is_a: GO:0044272 {is_inferred="true"} ! sulfur compound biosynthetic process
+is_a: GO:0046305 {is_inferred="true"} ! alkanesulfonate biosynthetic process
 is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
 
 [Term]
@@ -32154,6 +32729,7 @@
 [Term]
 id: GO:0042417 ! dopamine metabolic process
 is_a: GO:0006584 {is_inferred="true"} ! catecholamine metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 
 [Term]
 id: GO:0042418 ! epinephrine biosynthetic process
@@ -32211,6 +32787,7 @@
 id: GO:0042428 ! serotonin metabolic process
 is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
 is_a: GO:0042430 {is_inferred="true"} ! indole-containing compound metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 is_a: GO:1901160 {is_inferred="true"} ! primary amino compound metabolic process
 
 [Term]
@@ -32260,8 +32837,8 @@
 [Term]
 id: GO:0042437 ! indoleacetic acid catabolic process
 is_a: GO:0009683 {is_inferred="true"} ! indoleacetic acid metabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
 is_a: GO:0042436 {is_inferred="true"} ! indole-containing compound catabolic process
+is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 
 [Term]
 id: GO:0042438 ! melanin biosynthetic process
@@ -32280,6 +32857,7 @@
 
 [Term]
 id: GO:0042443 ! phenylethylamine metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 is_a: GO:1901160 {is_inferred="true"} ! primary amino compound metabolic process
 
 [Term]
@@ -32979,6 +33557,7 @@
 id: GO:0042818 ! pyridoxamine metabolic process
 is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
 is_a: GO:0042816 {is_inferred="true"} ! vitamin B6 metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
 
 [Term]
@@ -33001,13 +33580,21 @@
 
 [Term]
 id: GO:0042822 ! pyridoxal phosphate metabolic process
-is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
+is_a: GO:0006081 {is_inferred="true"} ! cellular aldehyde metabolic process
+is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
+is_a: GO:0006796 {is_inferred="true"} ! phosphate-containing compound metabolic process
+is_a: GO:0019637 {is_inferred="true"} ! organophosphate metabolic process
+is_a: GO:0072524 {is_inferred="true"} ! pyridine-containing compound metabolic process
+is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
 
 [Term]
 id: GO:0042823 ! pyridoxal phosphate biosynthetic process
+is_a: GO:0019438 {is_inferred="true"} ! aromatic compound biosynthetic process
 is_a: GO:0042822 {is_inferred="true"} ! pyridoxal phosphate metabolic process
-is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
+is_a: GO:0046184 {is_inferred="true"} ! aldehyde biosynthetic process
+is_a: GO:0072525 {is_inferred="true"} ! pyridine-containing compound biosynthetic process
+is_a: GO:0090407 {is_inferred="true"} ! organophosphate biosynthetic process
+is_a: GO:1901617 {is_inferred="true"} ! organic hydroxy compound biosynthetic process
 
 [Term]
 id: GO:0042824 ! MHC class I peptide loading complex
@@ -33130,9 +33717,9 @@
 
 [Term]
 id: GO:0042857 ! chrysobactin metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
 is_a: GO:0006518 {is_inferred="true"} ! peptide metabolic process
 is_a: GO:0009712 {is_inferred="true"} ! catechol-containing compound metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 is_a: GO:0034308 {is_inferred="true"} ! primary alcohol metabolic process
 is_a: GO:1901160 {is_inferred="true"} ! primary amino compound metabolic process
 
@@ -33139,18 +33726,18 @@
 [Term]
 id: GO:0042858 ! chrysobactin biosynthetic process
 is_a: GO:0009713 {is_inferred="true"} ! catechol-containing compound biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0034309 {is_inferred="true"} ! primary alcohol biosynthetic process
 is_a: GO:0042857 {is_inferred="true"} ! chrysobactin metabolic process
+is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 is_a: GO:1901162 {is_inferred="true"} ! primary amino compound biosynthetic process
 
 [Term]
 id: GO:0042859 ! chrysobactin catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
 is_a: GO:0019614 {is_inferred="true"} ! catechol-containing compound catabolic process
 is_a: GO:0034310 {is_inferred="true"} ! primary alcohol catabolic process
 is_a: GO:0042857 {is_inferred="true"} ! chrysobactin metabolic process
 is_a: GO:0043171 {is_inferred="true"} ! peptide catabolic process
+is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 is_a: GO:1901161 {is_inferred="true"} ! primary amino compound catabolic process
 
 [Term]
@@ -33169,27 +33756,27 @@
 
 [Term]
 id: GO:0042863 ! pyochelin metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
 is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
 is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
 is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
 
 [Term]
 id: GO:0042864 ! pyochelin biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
 is_a: GO:0042863 {is_inferred="true"} ! pyochelin metabolic process
 is_a: GO:0044272 {is_inferred="true"} ! sulfur compound biosynthetic process
 is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
+is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 
 [Term]
 id: GO:0042865 ! pyochelin catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
 is_a: GO:0019336 {is_inferred="true"} ! phenol-containing compound catabolic process
 is_a: GO:0042863 {is_inferred="true"} ! pyochelin metabolic process
 is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
 is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
+is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
 
 [Term]
@@ -33205,6 +33792,7 @@
 [Term]
 id: GO:0042869 ! aldarate transport
 is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
+is_a: GO:0008643 {is_inferred="true"} ! carbohydrate transport
 
 [Term]
 id: GO:0042870 ! D-glucarate transport
@@ -33212,6 +33800,7 @@
 
 [Term]
 id: GO:0042873 ! aldonate transport
+is_a: GO:0008643 {is_inferred="true"} ! carbohydrate transport
 is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
 
 [Term]
@@ -33224,7 +33813,8 @@
 
 [Term]
 id: GO:0042876 ! aldarate transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0005310 {is_inferred="true"} ! dicarboxylic acid transmembrane transporter activity
+is_a: GO:0015144 {is_inferred="true"} ! carbohydrate transmembrane transporter activity
 
 [Term]
 id: GO:0042878 ! D-glucarate transmembrane transporter activity
@@ -33232,7 +33822,8 @@
 
 [Term]
 id: GO:0042879 ! aldonate transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0008028 {is_inferred="true"} ! monocarboxylic acid transmembrane transporter activity
+is_a: GO:0015144 {is_inferred="true"} ! carbohydrate transmembrane transporter activity
 
 [Term]
 id: GO:0042880 ! D-glucuronate transmembrane transporter activity
@@ -33249,6 +33840,7 @@
 [Term]
 id: GO:0042883 ! cysteine transport
 is_a: GO:0000101 {is_inferred="true"} ! sulfur amino acid transport
+is_a: GO:0006812 {is_inferred="true"} ! cation transport
 
 [Term]
 id: GO:0042884 ! microcin transport
@@ -33286,8 +33878,8 @@
 
 [Term]
 id: GO:0042894 ! fosmidomycin transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0042886 {is_inferred="true"} ! amide transport
-is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 
 [Term]
 id: GO:0042897 ! polymyxin transporter activity
@@ -33308,14 +33900,12 @@
 
 [Term]
 id: GO:0042904 ! 9-cis-retinoic acid biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
-is_a: GO:0016102 {is_inferred="true"} ! diterpenoid biosynthetic process
+is_a: GO:0002138 {is_inferred="true"} ! retinoic acid biosynthetic process
 is_a: GO:0042905 {is_inferred="true"} ! 9-cis-retinoic acid metabolic process
 
 [Term]
 id: GO:0042905 ! 9-cis-retinoic acid metabolic process
-is_a: GO:0001523 {is_inferred="true"} ! retinoid metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0042573 {is_inferred="true"} ! retinoic acid metabolic process
 
 [Term]
 id: GO:0042906 ! xanthine transport
@@ -33348,7 +33938,7 @@
 
 [Term]
 id: GO:0042920 ! 3-hydroxyphenylpropionic acid transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
+is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
 is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
 
 [Term]
@@ -33366,11 +33956,12 @@
 
 [Term]
 id: GO:0042930 ! enterobactin transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
 
 [Term]
 id: GO:0042932 ! chrysobactin transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
+is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
 is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
 is_a: GO:0042938 {is_inferred="true"} ! dipeptide transport
 
@@ -33400,16 +33991,17 @@
 
 [Term]
 id: GO:0042940 ! D-amino acid transport
-is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
+is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
 
 [Term]
 id: GO:0042941 ! D-alanine transport
 is_a: GO:0032328 {is_inferred="true"} ! alanine transport
+is_a: GO:0042940 {is_inferred="true"} ! D-amino acid transport
 
 [Term]
 id: GO:0042942 ! D-serine transport
 is_a: GO:0032329 {is_inferred="true"} ! serine transport
+is_a: GO:0042940 {is_inferred="true"} ! D-amino acid transport
 
 [Term]
 id: GO:0042943 ! D-amino acid transmembrane transporter activity
@@ -33474,7 +34066,7 @@
 
 [Term]
 id: GO:0042968 ! homoserine transport
-is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:0015807 {is_inferred="true"} ! L-amino acid transport
 
 [Term]
 id: GO:0042969 ! lactone transport
@@ -33710,6 +34302,7 @@
 
 [Term]
 id: GO:0043092 ! L-amino acid import
+is_a: GO:0015807 {is_inferred="true"} ! L-amino acid transport
 is_a: GO:0043090 {is_inferred="true"} ! amino acid import
 
 [Term]
@@ -33881,6 +34474,8 @@
 
 [Term]
 id: GO:0043215 ! daunorubicin transport
+is_a: GO:0015695 {is_inferred="true"} ! organic cation transport
+is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 is_a: GO:1901656 {is_inferred="true"} ! glycoside transport
 
 [Term]
@@ -33975,6 +34570,7 @@
 [Term]
 id: GO:0043278 ! response to morphine
 is_a: GO:0014072 {is_inferred="true"} ! response to isoquinoline alkaloid
+is_a: GO:0060359 {is_inferred="true"} ! response to ammonium ion
 
 [Term]
 id: GO:0043279 ! response to alkaloid
@@ -34016,6 +34612,7 @@
 
 [Term]
 id: GO:0043295 ! glutathione binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:0072341 {is_inferred="true"} ! modified amino acid binding
 is_a: GO:1900750 {is_inferred="true"} ! oligopeptide binding
 is_a: GO:1901681 {is_inferred="true"} ! sulfur compound binding
@@ -34166,7 +34763,7 @@
 
 [Term]
 id: GO:0043325 ! phosphatidylinositol-3,4-bisphosphate binding
-is_a: GO:0043168 {is_inferred="true"} ! anion binding
+is_a: GO:1902936 {is_inferred="true"} ! phosphatidylinositol bisphosphate binding
 
 [Term]
 id: GO:0043328 ! protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
@@ -34283,6 +34880,7 @@
 
 [Term]
 id: GO:0043395 ! heparan sulfate proteoglycan binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:0043394 {is_inferred="true"} ! proteoglycan binding
 is_a: GO:1901681 {is_inferred="true"} ! sulfur compound binding
 
@@ -34362,10 +34960,13 @@
 
 [Term]
 id: GO:0043420 ! anthranilate metabolic process
+is_a: GO:0009072 {is_inferred="true"} ! aromatic amino acid family metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 
 [Term]
 id: GO:0043421 ! anthranilate catabolic process
+is_a: GO:0009074 {is_inferred="true"} ! aromatic amino acid family catabolic process
 is_a: GO:0043420 {is_inferred="true"} ! anthranilate metabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 
@@ -34384,12 +34985,18 @@
 is_a: GO:0043434 {is_inferred="true"} ! response to peptide hormone
 
 [Term]
+id: GO:0043438 ! acetoacetic acid metabolic process
+is_a: GO:1902224 {is_inferred="true"} ! ketone body metabolic process
+
+[Term]
 id: GO:0043441 ! acetoacetic acid biosynthetic process
 is_a: GO:0043438 {is_inferred="true"} ! acetoacetic acid metabolic process
+is_a: GO:0046951 {is_inferred="true"} ! ketone body biosynthetic process
 
 [Term]
 id: GO:0043442 ! acetoacetic acid catabolic process
 is_a: GO:0043438 {is_inferred="true"} ! acetoacetic acid metabolic process
+is_a: GO:0046952 {is_inferred="true"} ! ketone body catabolic process
 
 [Term]
 id: GO:0043443 ! acetone metabolic process
@@ -34619,8 +35226,13 @@
 id: GO:0043531 ! ADP binding
 is_a: GO:0032550 {is_inferred="true"} ! purine ribonucleoside binding
 is_a: GO:0032559 {is_inferred="true"} ! adenyl ribonucleotide binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
 [Term]
+id: GO:0043533 ! inositol 1,3,4,5 tetrakisphosphate binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
+
+[Term]
 id: GO:0043535 ! regulation of blood vessel endothelial cell migration
 is_a: GO:0010594 {is_inferred="true"} ! regulation of endothelial cell migration
 
@@ -34871,7 +35483,9 @@
 [Term]
 id: GO:0043639 ! benzoate catabolic process
 is_a: GO:0018874 {is_inferred="true"} ! benzoate metabolic process
+is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
+is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
 
 [Term]
 id: GO:0043641 ! novobiocin metabolic process
@@ -34987,25 +35601,28 @@
 [Term]
 id: GO:0043858 ! arginine:ornithine antiporter activity
 is_a: GO:0015181 {is_inferred="true"} ! arginine transmembrane transporter activity
-is_a: GO:0015297 {is_inferred="true"} ! antiporter activity
+is_a: GO:0015301 {is_inferred="true"} ! anion:anion antiporter activity
+is_a: GO:0015491 {is_inferred="true"} ! cation:cation antiporter activity
 
 [Term]
 id: GO:0043861 ! agmatine:putrescine antiporter activity
-is_a: GO:0015297 {is_inferred="true"} ! antiporter activity
 is_a: GO:0015489 {is_inferred="true"} ! putrescine transmembrane transporter activity
+is_a: GO:0015491 {is_inferred="true"} ! cation:cation antiporter activity
 
 [Term]
 id: GO:0043862 ! arginine:agmatine antiporter activity
+is_a: GO:0015101 {is_inferred="true"} ! organic cation transmembrane transporter activity
 is_a: GO:0015181 {is_inferred="true"} ! arginine transmembrane transporter activity
-is_a: GO:0015297 {is_inferred="true"} ! antiporter activity
+is_a: GO:0015491 {is_inferred="true"} ! cation:cation antiporter activity
 
 [Term]
 id: GO:0043865 ! methionine transmembrane transporter activity
 is_a: GO:0000099 {is_inferred="true"} ! sulfur amino acid transmembrane transporter activity
+is_a: GO:0008324 {is_inferred="true"} ! cation transmembrane transporter activity
 
 [Term]
 id: GO:0043872 ! lysine:cadaverine antiporter activity
-is_a: GO:0015297 {is_inferred="true"} ! antiporter activity
+is_a: GO:0015491 {is_inferred="true"} ! cation:cation antiporter activity
 
 [Term]
 id: GO:0043879 ! glycolate transmembrane transporter activity
@@ -35014,7 +35631,7 @@
 
 [Term]
 id: GO:0043882 ! malate:sodium symporter activity
-is_a: GO:0015081 {is_inferred="true"} ! sodium ion transmembrane transporter activity
+is_a: GO:0005343 {is_inferred="true"} ! organic acid:sodium symporter activity
 
 [Term]
 id: GO:0043887 ! melibiose:sodium symporter activity
@@ -35625,8 +36242,7 @@
 
 [Term]
 id: GO:0044539 ! long-chain fatty acid import
-is_a: GO:0006869 {is_inferred="true"} ! lipid transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
+is_a: GO:0015909 {is_inferred="true"} ! long-chain fatty acid transport
 
 [Term]
 id: GO:0044545 ! NSL complex
@@ -35678,6 +36294,7 @@
 id: GO:0044597 ! daunorubicin metabolic process
 is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
 is_a: GO:0030638 {is_inferred="true"} ! polyketide metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
 is_a: GO:1901661 {is_inferred="true"} ! quinone metabolic process
 
@@ -35685,17 +36302,19 @@
 id: GO:0044598 ! doxorubicin metabolic process
 is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
 is_a: GO:0030638 {is_inferred="true"} ! polyketide metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
 is_a: GO:1901661 {is_inferred="true"} ! quinone metabolic process
 
 [Term]
 id: GO:0044610 ! FMN transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:0015215 {is_inferred="true"} ! nucleotide transmembrane transporter activity
 is_a: GO:1901505 {is_inferred="true"} ! carbohydrate derivative transporter activity
 
 [Term]
 id: GO:0044667 ! (R)-carnitine:4-(trimethylammonio)butanoate antiporter activity
-is_a: GO:0015297 {is_inferred="true"} ! antiporter activity
+is_a: GO:0015491 {is_inferred="true"} ! cation:cation antiporter activity
 is_a: GO:1901235 {is_inferred="true"} ! (R)-carnitine transmembrane transporter activity
 is_a: GO:1901236 {is_inferred="true"} ! 4-(trimethylammonio)butanoate transmembrane transporter activity
 
@@ -35729,7 +36348,7 @@
 
 [Term]
 id: GO:0044690 ! methionine import
-is_a: GO:0000101 {is_inferred="true"} ! sulfur amino acid transport
+is_a: GO:0015821 {is_inferred="true"} ! methionine transport
 is_a: GO:0043090 {is_inferred="true"} ! amino acid import
 
 [Term]
@@ -37041,8 +37660,8 @@
 [Term]
 id: GO:0045487 ! gibberellin catabolic process
 is_a: GO:0009685 {is_inferred="true"} ! gibberellin metabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
 is_a: GO:0016103 {is_inferred="true"} ! diterpenoid catabolic process
+is_a: GO:0046395 {is_inferred="true"} ! carboxylic acid catabolic process
 
 [Term]
 id: GO:0045488 ! pectin metabolic process
@@ -39312,13 +39931,14 @@
 
 [Term]
 id: GO:0046046 ! TTP metabolic process
-is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
+is_a: GO:0009208 {is_inferred="true"} ! pyrimidine ribonucleoside triphosphate metabolic process
+is_a: GO:0009218 {is_inferred="true"} ! pyrimidine ribonucleotide metabolic process
 
 [Term]
 id: GO:0046047 ! TTP catabolic process
+is_a: GO:0009210 {is_inferred="true"} ! pyrimidine ribonucleoside triphosphate catabolic process
+is_a: GO:0009222 {is_inferred="true"} ! pyrimidine ribonucleotide catabolic process
 is_a: GO:0046046 {is_inferred="true"} ! TTP metabolic process
-is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
 
 [Term]
 id: GO:0046048 ! UDP metabolic process
@@ -40032,6 +40652,7 @@
 id: GO:0046202 ! cyanide biosynthetic process
 is_a: GO:0019499 {is_inferred="true"} ! cyanide metabolic process
 is_a: GO:0044711 {is_inferred="true"} ! single-organism biosynthetic process
+is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
 
 [Term]
 id: GO:0046203 ! spermidine catabolic process
@@ -40038,6 +40659,10 @@
 is_a: GO:0008216 {is_inferred="true"} ! spermidine metabolic process
 
 [Term]
+id: GO:0046204 ! nor-spermidine metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
+
+[Term]
 id: GO:0046205 ! nor-spermidine catabolic process
 is_a: GO:0046204 {is_inferred="true"} ! nor-spermidine metabolic process
 
@@ -40133,12 +40758,16 @@
 [Term]
 id: GO:0046228 ! 2,4,5-trichlorophenoxyacetic acid catabolic process
 is_a: GO:0018980 {is_inferred="true"} ! 2,4,5-trichlorophenoxyacetic acid metabolic process
+is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
+is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
+is_a: GO:1901502 {is_inferred="true"} ! ether catabolic process
 
 [Term]
 id: GO:0046230 ! 2-aminobenzenesulfonate catabolic process
 is_a: GO:0018868 {is_inferred="true"} ! 2-aminobenzenesulfonate metabolic process
 is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
+is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
 is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
 is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
 
@@ -40153,12 +40782,16 @@
 [Term]
 id: GO:0046235 ! gallate biosynthetic process
 is_a: GO:0018918 {is_inferred="true"} ! gallate metabolic process
+is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 
 [Term]
 id: GO:0046236 ! mandelate biosynthetic process
 is_a: GO:0018924 {is_inferred="true"} ! mandelate metabolic process
+is_a: GO:0019438 {is_inferred="true"} ! aromatic compound biosynthetic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
+is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
+is_a: GO:1901617 {is_inferred="true"} ! organic hydroxy compound biosynthetic process
 
 [Term]
 id: GO:0046239 ! phthalate catabolic process
@@ -40170,6 +40803,7 @@
 [Term]
 id: GO:0046244 ! salicylic acid catabolic process
 is_a: GO:0009696 {is_inferred="true"} ! salicylic acid metabolic process
+is_a: GO:0019336 {is_inferred="true"} ! phenol-containing compound catabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 
 [Term]
@@ -40226,6 +40860,7 @@
 id: GO:0046265 ! thiocyanate catabolic process
 is_a: GO:0018969 {is_inferred="true"} ! thiocyanate metabolic process
 is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
+is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
 
 [Term]
 id: GO:0046267 ! triethanolamine catabolic process
@@ -40236,7 +40871,8 @@
 [Term]
 id: GO:0046269 ! toluene-4-sulfonate catabolic process
 is_a: GO:0018972 {is_inferred="true"} ! toluene-4-sulfonate metabolic process
-is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
+is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
+is_a: GO:0072491 {is_inferred="true"} ! toluene-containing compound catabolic process
 
 [Term]
 id: GO:0046271 ! phenylpropanoid catabolic process
@@ -40268,19 +40904,24 @@
 [Term]
 id: GO:0046276 ! methylgallate catabolic process
 is_a: GO:0019489 {is_inferred="true"} ! methylgallate metabolic process
+is_a: GO:0019614 {is_inferred="true"} ! catechol-containing compound catabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 
 [Term]
 id: GO:0046277 ! methylgallate biosynthetic process
+is_a: GO:0009713 {is_inferred="true"} ! catechol-containing compound biosynthetic process
 is_a: GO:0019489 {is_inferred="true"} ! methylgallate metabolic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 
 [Term]
 id: GO:0046278 ! 3,4-dihydroxybenzoate metabolic process
+is_a: GO:0009712 {is_inferred="true"} ! catechol-containing compound metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 
 [Term]
 id: GO:0046279 ! 3,4-dihydroxybenzoate biosynthetic process
+is_a: GO:0009713 {is_inferred="true"} ! catechol-containing compound biosynthetic process
 is_a: GO:0046278 {is_inferred="true"} ! 3,4-dihydroxybenzoate metabolic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 
@@ -40345,22 +40986,29 @@
 [Term]
 id: GO:0046295 ! glycolate biosynthetic process
 is_a: GO:0009441 {is_inferred="true"} ! glycolate metabolic process
+is_a: GO:0034309 {is_inferred="true"} ! primary alcohol biosynthetic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 
 [Term]
 id: GO:0046296 ! glycolate catabolic process
 is_a: GO:0009441 {is_inferred="true"} ! glycolate metabolic process
+is_a: GO:0034310 {is_inferred="true"} ! primary alcohol catabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 
 [Term]
 id: GO:0046298 ! 2,4-dichlorobenzoate catabolic process
 is_a: GO:0018898 {is_inferred="true"} ! 2,4-dichlorobenzoate metabolic process
+is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
+is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
 
 [Term]
 id: GO:0046300 ! 2,4-dichlorophenoxyacetic acid catabolic process
 is_a: GO:0018901 {is_inferred="true"} ! 2,4-dichlorophenoxyacetic acid metabolic process
+is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
+is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
+is_a: GO:1901502 {is_inferred="true"} ! ether catabolic process
 
 [Term]
 id: GO:0046302 ! 2-chloro-N-isopropylacetanilide catabolic process
@@ -40406,6 +41054,7 @@
 
 [Term]
 id: GO:0046311 ! prenylcysteine biosynthetic process
+is_a: GO:0000097 {is_inferred="true"} ! sulfur amino acid biosynthetic process
 is_a: GO:0030329 {is_inferred="true"} ! prenylcysteine metabolic process
 is_a: GO:0042398 {is_inferred="true"} ! cellular modified amino acid biosynthetic process
 
@@ -40490,6 +41139,7 @@
 id: GO:0046333 ! octopamine metabolic process
 is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
 is_a: GO:0042439 {is_inferred="true"} ! ethanolamine-containing compound metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 
 [Term]
 id: GO:0046334 ! octopamine catabolic process
@@ -40549,6 +41199,9 @@
 [Term]
 id: GO:0046345 ! abscisic acid catabolic process
 is_a: GO:0009687 {is_inferred="true"} ! abscisic acid metabolic process
+is_a: GO:0016107 {is_inferred="true"} ! sesquiterpenoid catabolic process
+is_a: GO:0043290 {is_inferred="true"} ! apocarotenoid catabolic process
+is_a: GO:0046164 {is_inferred="true"} ! alcohol catabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 
 [Term]
@@ -40654,6 +41307,7 @@
 
 [Term]
 id: GO:0046368 ! GDP-L-fucose metabolic process
+is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
 is_a: GO:0009225 {is_inferred="true"} ! nucleotide-sugar metabolic process
 
 [Term]
@@ -40705,14 +41359,17 @@
 [Term]
 id: GO:0046380 ! N-acetylneuraminate biosynthetic process
 is_a: GO:0006054 {is_inferred="true"} ! N-acetylneuraminate metabolic process
+is_a: GO:0046349 {is_inferred="true"} ! amino sugar biosynthetic process
 is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 
 [Term]
 id: GO:0046381 ! CMP-N-acetylneuraminate metabolic process
+is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
 is_a: GO:0009225 {is_inferred="true"} ! nucleotide-sugar metabolic process
 
 [Term]
 id: GO:0046382 ! GDP-D-rhamnose metabolic process
+is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
 is_a: GO:0009225 {is_inferred="true"} ! nucleotide-sugar metabolic process
 
 [Term]
@@ -40773,24 +41430,30 @@
 [Term]
 id: GO:0046397 ! galacturonate catabolic process
 is_a: GO:0019586 {is_inferred="true"} ! galacturonate metabolic process
+is_a: GO:0046365 {is_inferred="true"} ! monosaccharide catabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 
 [Term]
 id: GO:0046398 ! UDP-glucuronate metabolic process
+is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
 is_a: GO:0009225 {is_inferred="true"} ! nucleotide-sugar metabolic process
+is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 
 [Term]
 id: GO:0046399 ! glucuronate biosynthetic process
 is_a: GO:0019585 {is_inferred="true"} ! glucuronate metabolic process
+is_a: GO:0046364 {is_inferred="true"} ! monosaccharide biosynthetic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 
 [Term]
 id: GO:0046400 ! keto-3-deoxy-D-manno-octulosonic acid metabolic process
+is_a: GO:0005996 {is_inferred="true"} ! monosaccharide metabolic process
 is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 
 [Term]
 id: GO:0046411 ! 2-keto-3-deoxygluconate transport
-is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
+is_a: GO:0015749 {is_inferred="true"} ! monosaccharide transport
+is_a: GO:0042873 {is_inferred="true"} ! aldonate transport
 
 [Term]
 id: GO:0046412 ! phenylmercury acetate metabolic process
@@ -40808,8 +41471,12 @@
 is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
 
 [Term]
+id: GO:0046415 ! urate metabolic process
+is_a: GO:0072521 {is_inferred="true"} ! purine-containing compound metabolic process
+
+[Term]
 id: GO:0046416 ! D-amino acid metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
+is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
 
 [Term]
 id: GO:0046417 ! chorismate metabolic process
@@ -40817,13 +41484,15 @@
 
 [Term]
 id: GO:0046418 ! nopaline metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
 is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
+is_a: GO:0072350 {is_inferred="true"} ! tricarboxylic acid metabolic process
+is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
 
 [Term]
 id: GO:0046419 ! octopine metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
 is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
+is_a: GO:0043648 {is_inferred="true"} ! dicarboxylic acid metabolic process
+is_a: GO:0046416 {is_inferred="true"} ! D-amino acid metabolic process
 
 [Term]
 id: GO:0046425 ! regulation of JAK-STAT cascade
@@ -40868,18 +41537,22 @@
 is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
 
 [Term]
+id: GO:0046436 ! D-alanine metabolic process
+is_a: GO:0046416 {is_inferred="true"} ! D-amino acid metabolic process
+
+[Term]
 id: GO:0046437 ! D-amino acid biosynthetic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 is_a: GO:0046416 {is_inferred="true"} ! D-amino acid metabolic process
+is_a: GO:1901607 {is_inferred="true"} ! alpha-amino acid biosynthetic process
 
 [Term]
 id: GO:0046438 ! D-cysteine metabolic process
-is_a: GO:0000096 {is_inferred="true"} ! sulfur amino acid metabolic process
-is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
+is_a: GO:0006534 {is_inferred="true"} ! cysteine metabolic process
+is_a: GO:0046416 {is_inferred="true"} ! D-amino acid metabolic process
 
 [Term]
 id: GO:0046439 ! L-cysteine metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
+is_a: GO:0006534 {is_inferred="true"} ! cysteine metabolic process
 
 [Term]
 id: GO:0046440 ! L-lysine metabolic process
@@ -40888,10 +41561,12 @@
 [Term]
 id: GO:0046441 ! D-lysine metabolic process
 is_a: GO:0006553 {is_inferred="true"} ! lysine metabolic process
+is_a: GO:0046416 {is_inferred="true"} ! D-amino acid metabolic process
 
 [Term]
 id: GO:0046442 ! aerobactin metabolic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
+is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
+is_a: GO:0072350 {is_inferred="true"} ! tricarboxylic acid metabolic process
 
 [Term]
 id: GO:0046443 ! FAD metabolic process
@@ -40930,14 +41605,20 @@
 [Term]
 id: GO:0046450 ! dethiobiotin metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0043603 {is_inferred="true"} ! cellular amide metabolic process
+is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
+is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
+is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
 
 [Term]
 id: GO:0046451 ! diaminopimelate metabolic process
+is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
 is_a: GO:0043648 {is_inferred="true"} ! dicarboxylic acid metabolic process
 
 [Term]
 id: GO:0046452 ! dihydrofolate metabolic process
 is_a: GO:0006760 {is_inferred="true"} ! folic acid-containing compound metabolic process
+is_a: GO:0043648 {is_inferred="true"} ! dicarboxylic acid metabolic process
 
 [Term]
 id: GO:0046453 ! dipyrrin metabolic process
@@ -40959,6 +41640,7 @@
 id: GO:0046456 ! icosanoid biosynthetic process
 is_a: GO:0006690 {is_inferred="true"} ! icosanoid metabolic process
 is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
+is_a: GO:1901570 {is_inferred="true"} ! fatty acid derivative biosynthetic process
 
 [Term]
 id: GO:0046457 ! prostanoid biosynthetic process
@@ -41014,8 +41696,7 @@
 
 [Term]
 id: GO:0046473 ! phosphatidic acid metabolic process
-is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
+is_a: GO:0006650 {is_inferred="true"} ! glycerophospholipid metabolic process
 
 [Term]
 id: GO:0046474 ! glycerophospholipid biosynthetic process
@@ -41054,8 +41735,9 @@
 
 [Term]
 id: GO:0046482 ! para-aminobenzoic acid metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
+is_a: GO:0009072 {is_inferred="true"} ! aromatic amino acid family metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 
 [Term]
 id: GO:0046485 ! ether lipid metabolic process
@@ -41063,6 +41745,7 @@
 
 [Term]
 id: GO:0046487 ! glyoxylate metabolic process
+is_a: GO:0006081 {is_inferred="true"} ! cellular aldehyde metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 
 [Term]
@@ -41089,7 +41772,7 @@
 
 [Term]
 id: GO:0046494 ! rhizobactin 1021 metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 is_a: GO:0043603 {is_inferred="true"} ! cellular amide metabolic process
 is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
 is_a: GO:1902644 {is_inferred="true"} ! tertiary alcohol metabolic process
@@ -41116,10 +41799,12 @@
 id: GO:0046499 ! S-adenosylmethioninamine metabolic process
 is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
 is_a: GO:0046128 {is_inferred="true"} ! purine ribonucleoside metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 
 [Term]
 id: GO:0046500 ! S-adenosylmethionine metabolic process
 is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
+is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
 
 [Term]
 id: GO:0046501 ! protoporphyrinogen IX metabolic process
@@ -41127,6 +41812,7 @@
 
 [Term]
 id: GO:0046502 ! uroporphyrinogen III metabolic process
+is_a: GO:0006778 {is_inferred="true"} ! porphyrin-containing compound metabolic process
 is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 
 [Term]
@@ -41142,6 +41828,7 @@
 [Term]
 id: GO:0046505 ! sulfolipid metabolic process
 is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
+is_a: GO:0043436 {is_inferred="true"} ! oxoacid metabolic process
 
 [Term]
 id: GO:0046506 ! sulfolipid biosynthetic process
@@ -41191,6 +41878,7 @@
 [Term]
 id: GO:0046519 ! sphingoid metabolic process
 is_a: GO:0006665 {is_inferred="true"} ! sphingolipid metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 
 [Term]
 id: GO:0046520 ! sphingoid biosynthetic process
@@ -41488,21 +42176,19 @@
 
 [Term]
 id: GO:0046655 ! folic acid metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
 is_a: GO:0006760 {is_inferred="true"} ! folic acid-containing compound metabolic process
-is_a: GO:0043603 {is_inferred="true"} ! cellular amide metabolic process
+is_a: GO:0043648 {is_inferred="true"} ! dicarboxylic acid metabolic process
 
 [Term]
 id: GO:0046656 ! folic acid biosynthetic process
 is_a: GO:0009396 {is_inferred="true"} ! folic acid-containing compound biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
-is_a: GO:0043604 {is_inferred="true"} ! amide biosynthetic process
+is_a: GO:0043650 {is_inferred="true"} ! dicarboxylic acid biosynthetic process
 is_a: GO:0046655 {is_inferred="true"} ! folic acid metabolic process
 
 [Term]
 id: GO:0046657 ! folic acid catabolic process
 is_a: GO:0009397 {is_inferred="true"} ! folic acid-containing compound catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
+is_a: GO:0043649 {is_inferred="true"} ! dicarboxylic acid catabolic process
 is_a: GO:0046655 {is_inferred="true"} ! folic acid metabolic process
 
 [Term]
@@ -41577,8 +42263,7 @@
 
 [Term]
 id: GO:0046681 ! response to carbamate
-is_a: GO:0010243 {is_inferred="true"} ! response to organonitrogen compound
-is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
+is_a: GO:0043200 {is_inferred="true"} ! response to amino acid
 
 [Term]
 id: GO:0046682 ! response to cyclodiene
@@ -41870,6 +42555,7 @@
 [Term]
 id: GO:0046874 ! quinolinate metabolic process
 is_a: GO:0043648 {is_inferred="true"} ! dicarboxylic acid metabolic process
+is_a: GO:0072524 {is_inferred="true"} ! pyridine-containing compound metabolic process
 
 [Term]
 id: GO:0046876 ! 3,4-didehydroretinal binding
@@ -42020,19 +42706,24 @@
 [Term]
 id: GO:0046942 ! carboxylic acid transport
 is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
+is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
 
 [Term]
+id: GO:0046943 ! carboxylic acid transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+
+[Term]
 id: GO:0046946 ! hydroxylysine metabolic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
+is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
 
 [Term]
 id: GO:0046947 ! hydroxylysine biosynthetic process
-is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
+is_a: GO:0042398 {is_inferred="true"} ! cellular modified amino acid biosynthetic process
 is_a: GO:0046946 {is_inferred="true"} ! hydroxylysine metabolic process
 
 [Term]
 id: GO:0046948 ! hydroxylysine catabolic process
-is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
+is_a: GO:0042219 {is_inferred="true"} ! cellular modified amino acid catabolic process
 is_a: GO:0046946 {is_inferred="true"} ! hydroxylysine metabolic process
 
 [Term]
@@ -42056,6 +42747,7 @@
 
 [Term]
 id: GO:0046963 ! 3'-phosphoadenosine 5'-phosphosulfate transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015858 {is_inferred="true"} ! nucleoside transport
 is_a: GO:0015868 {is_inferred="true"} ! purine ribonucleotide transport
 is_a: GO:0051503 {is_inferred="true"} ! adenine nucleotide transport
@@ -42065,6 +42757,7 @@
 id: GO:0046964 ! 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity
 is_a: GO:0000295 {is_inferred="true"} ! adenine nucleotide transmembrane transporter activity
 is_a: GO:0005346 {is_inferred="true"} ! purine ribonucleotide transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:0015211 {is_inferred="true"} ! purine nucleoside transmembrane transporter activity
 is_a: GO:1901682 {is_inferred="true"} ! sulfur compound transmembrane transporter activity
 
@@ -42153,6 +42846,7 @@
 [Term]
 id: GO:0048032 ! galacturonate binding
 is_a: GO:0033293 {is_inferred="true"} ! monocarboxylic acid binding
+is_a: GO:0048029 {is_inferred="true"} ! monosaccharide binding
 
 [Term]
 id: GO:0048033 ! heme o metabolic process
@@ -42823,6 +43517,7 @@
 [Term]
 id: GO:0048473 ! D-methionine transport
 is_a: GO:0015821 {is_inferred="true"} ! methionine transport
+is_a: GO:0042940 {is_inferred="true"} ! D-amino acid transport
 
 [Term]
 id: GO:0048474 ! D-methionine transmembrane transporter activity
@@ -43557,6 +44252,7 @@
 is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
 is_a: GO:0009150 {is_inferred="true"} ! purine ribonucleotide metabolic process
 is_a: GO:0034035 {is_inferred="true"} ! purine ribonucleoside bisphosphate metabolic process
+is_a: GO:0043436 {is_inferred="true"} ! oxoacid metabolic process
 is_a: GO:0046128 {is_inferred="true"} ! purine ribonucleoside metabolic process
 
 [Term]
@@ -43594,6 +44290,7 @@
 [Term]
 id: GO:0050542 ! icosanoid binding
 is_a: GO:0031406 {is_inferred="true"} ! carboxylic acid binding
+is_a: GO:1901567 {is_inferred="true"} ! fatty acid derivative binding
 
 [Term]
 id: GO:0050543 ! icosatetraenoic acid binding
@@ -43606,14 +44303,13 @@
 
 [Term]
 id: GO:0050646 ! 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding
-is_a: GO:0008289 {is_inferred="true"} ! lipid binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
+is_a: GO:0036041 {is_inferred="true"} ! long-chain fatty acid binding
+is_a: GO:0050542 {is_inferred="true"} ! icosanoid binding
 
 [Term]
 id: GO:0050647 ! 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding
-is_a: GO:0008289 {is_inferred="true"} ! lipid binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
-is_a: GO:1901567 {is_inferred="true"} ! fatty acid derivative binding
+is_a: GO:0036041 {is_inferred="true"} ! long-chain fatty acid binding
+is_a: GO:0050542 {is_inferred="true"} ! icosanoid binding
 
 [Term]
 id: GO:0050648 ! 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding
@@ -43625,6 +44321,7 @@
 is_a: GO:0006024 {is_inferred="true"} ! glycosaminoglycan biosynthetic process
 is_a: GO:0030166 {is_inferred="true"} ! proteoglycan biosynthetic process
 is_a: GO:0044272 {is_inferred="true"} ! sulfur compound biosynthetic process
+is_a: GO:0044711 {is_inferred="true"} ! single-organism biosynthetic process
 is_a: GO:0050654 {is_inferred="true"} ! chondroitin sulfate proteoglycan metabolic process
 
 [Term]
@@ -43637,6 +44334,7 @@
 is_a: GO:0006029 {is_inferred="true"} ! proteoglycan metabolic process
 is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
 is_a: GO:0030203 {is_inferred="true"} ! glycosaminoglycan metabolic process
+is_a: GO:0043436 {is_inferred="true"} ! oxoacid metabolic process
 
 [Term]
 id: GO:0050655 ! dermatan sulfate proteoglycan metabolic process
@@ -43646,6 +44344,7 @@
 id: GO:0050656 ! 3'-phosphoadenosine 5'-phosphosulfate binding
 is_a: GO:0032550 {is_inferred="true"} ! purine ribonucleoside binding
 is_a: GO:0032559 {is_inferred="true"} ! adenyl ribonucleotide binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:1901681 {is_inferred="true"} ! sulfur compound binding
 
 [Term]
@@ -43659,6 +44358,7 @@
 [Term]
 id: GO:0050660 ! flavin adenine dinucleotide binding
 is_a: GO:0000166 {is_inferred="true"} ! nucleotide binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
 [Term]
 id: GO:0050661 ! NADP binding
@@ -44065,6 +44765,7 @@
 id: GO:0050783 ! cocaine metabolic process
 is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
 is_a: GO:0046448 {is_inferred="true"} ! tropane alkaloid metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 
 [Term]
 id: GO:0050784 ! cocaine catabolic process
@@ -44158,6 +44859,7 @@
 id: GO:0050812 ! regulation of acyl-CoA biosynthetic process
 is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
 is_a: GO:0042762 {is_inferred="true"} ! regulation of sulfur metabolic process
+is_a: GO:0051174 {is_inferred="true"} ! regulation of phosphorus metabolic process
 is_a: GO:0051196 {is_inferred="true"} ! regulation of coenzyme metabolic process
 
 [Term]
@@ -44202,12 +44904,13 @@
 
 [Term]
 id: GO:0050833 ! pyruvate transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0008028 {is_inferred="true"} ! monocarboxylic acid transmembrane transporter activity
 
 [Term]
 id: GO:0050843 ! S-adenosylmethionine catabolic process
 is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
 is_a: GO:0046500 {is_inferred="true"} ! S-adenosylmethionine metabolic process
+is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
 
 [Term]
 id: GO:0050845 ! teichuronic acid biosynthetic process
@@ -44785,14 +45488,14 @@
 
 [Term]
 id: GO:0051071 ! 4,6-pyruvylated galactose residue metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 is_a: GO:0044723 {is_inferred="true"} ! single-organism carbohydrate metabolic process
 is_a: GO:1901135 {is_inferred="true"} ! carbohydrate derivative metabolic process
 
 [Term]
 id: GO:0051072 ! 4,6-pyruvylated galactose residue biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0051071 {is_inferred="true"} ! 4,6-pyruvylated galactose residue metabolic process
+is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 is_a: GO:1901137 {is_inferred="true"} ! carbohydrate derivative biosynthetic process
 
 [Term]
@@ -44890,9 +45593,11 @@
 [Term]
 id: GO:0051121 ! hepoxilin metabolic process
 is_a: GO:0001676 {is_inferred="true"} ! long-chain fatty acid metabolic process
+is_a: GO:0033559 {is_inferred="true"} ! unsaturated fatty acid metabolic process
 
 [Term]
 id: GO:0051122 ! hepoxilin biosynthetic process
+is_a: GO:0006636 {is_inferred="true"} ! unsaturated fatty acid biosynthetic process
 is_a: GO:0042759 {is_inferred="true"} ! long-chain fatty acid biosynthetic process
 is_a: GO:0051121 {is_inferred="true"} ! hepoxilin metabolic process
 
@@ -45588,6 +46293,7 @@
 
 [Term]
 id: GO:0051378 ! serotonin binding
+is_a: GO:0070405 {is_inferred="true"} ! ammonium ion binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
 
@@ -45601,6 +46307,7 @@
 
 [Term]
 id: GO:0051381 ! histamine binding
+is_a: GO:0070405 {is_inferred="true"} ! ammonium ion binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
 
@@ -45660,6 +46367,7 @@
 [Term]
 id: GO:0051407 ! glycerone phosphate:inorganic phosphate antiporter activity
 is_a: GO:0005315 {is_inferred="true"} ! inorganic phosphate transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:0015605 {is_inferred="true"} ! organophosphate ester transmembrane transporter activity
 is_a: GO:1901505 {is_inferred="true"} ! carbohydrate derivative transporter activity
 
@@ -45666,6 +46374,7 @@
 [Term]
 id: GO:0051408 ! glyceraldehyde 3-phosphate:inorganic phosphate antiporter activity
 is_a: GO:0005315 {is_inferred="true"} ! inorganic phosphate transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:0015605 {is_inferred="true"} ! organophosphate ester transmembrane transporter activity
 is_a: GO:1901505 {is_inferred="true"} ! carbohydrate derivative transporter activity
 
@@ -45813,7 +46522,7 @@
 
 [Term]
 id: GO:0051470 ! ectoine transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
+is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
 is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
@@ -45842,7 +46551,7 @@
 [Term]
 id: GO:0051476 ! mannosylglycerate transport
 is_a: GO:0008643 {is_inferred="true"} ! carbohydrate transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
 is_a: GO:1901656 {is_inferred="true"} ! glycoside transport
 
 [Term]
@@ -45852,14 +46561,14 @@
 
 [Term]
 id: GO:0051478 ! mannosylglycerate metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
 is_a: GO:0016137 {is_inferred="true"} ! glycoside metabolic process
+is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 is_a: GO:0044723 {is_inferred="true"} ! single-organism carbohydrate metabolic process
 
 [Term]
 id: GO:0051479 ! mannosylglycerate biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0016138 {is_inferred="true"} ! glycoside biosynthetic process
+is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 is_a: GO:0051478 {is_inferred="true"} ! mannosylglycerate metabolic process
 
 [Term]
@@ -46147,11 +46856,13 @@
 [Term]
 id: GO:0051584 ! regulation of dopamine uptake involved in synaptic transmission
 is_a: GO:0032225 {is_inferred="true"} ! regulation of synaptic transmission, dopaminergic
+is_a: GO:0043269 {is_inferred="true"} ! regulation of ion transport
 is_a: GO:0051940 {is_inferred="true"} ! regulation of catecholamine uptake involved in synaptic transmission
 
 [Term]
 id: GO:0051585 ! negative regulation of dopamine uptake involved in synaptic transmission
 is_a: GO:0032227 {is_inferred="true"} ! negative regulation of synaptic transmission, dopaminergic
+is_a: GO:0043271 {is_inferred="true"} ! negative regulation of ion transport
 is_a: GO:0051584 {is_inferred="true"} ! regulation of dopamine uptake involved in synaptic transmission
 is_a: GO:0051945 {is_inferred="true"} ! negative regulation of catecholamine uptake involved in synaptic transmission
 
@@ -46158,6 +46869,7 @@
 [Term]
 id: GO:0051586 ! positive regulation of dopamine uptake involved in synaptic transmission
 is_a: GO:0032226 {is_inferred="true"} ! positive regulation of synaptic transmission, dopaminergic
+is_a: GO:0043270 {is_inferred="true"} ! positive regulation of ion transport
 is_a: GO:0051584 {is_inferred="true"} ! regulation of dopamine uptake involved in synaptic transmission
 is_a: GO:0051944 {is_inferred="true"} ! positive regulation of catecholamine uptake involved in synaptic transmission
 
@@ -46221,6 +46933,7 @@
 
 [Term]
 id: GO:0051608 ! histamine transport
+is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 is_a: GO:0045117 {is_inferred="true"} ! azole transport
 
 [Term]
@@ -46230,16 +46943,19 @@
 
 [Term]
 id: GO:0051611 ! regulation of serotonin uptake
+is_a: GO:0043269 {is_inferred="true"} ! regulation of ion transport
 is_a: GO:0051580 {is_inferred="true"} ! regulation of neurotransmitter uptake
 is_a: GO:0060341 {is_inferred="true"} ! regulation of cellular localization
 
 [Term]
 id: GO:0051612 ! negative regulation of serotonin uptake
+is_a: GO:0043271 {is_inferred="true"} ! negative regulation of ion transport
 is_a: GO:0051581 {is_inferred="true"} ! negative regulation of neurotransmitter uptake
 is_a: GO:0051611 {is_inferred="true"} ! regulation of serotonin uptake
 
 [Term]
 id: GO:0051613 ! positive regulation of serotonin uptake
+is_a: GO:0043270 {is_inferred="true"} ! positive regulation of ion transport
 is_a: GO:0051582 {is_inferred="true"} ! positive regulation of neurotransmitter uptake
 is_a: GO:0051611 {is_inferred="true"} ! regulation of serotonin uptake
 
@@ -46249,15 +46965,18 @@
 
 [Term]
 id: GO:0051616 ! regulation of histamine uptake
+is_a: GO:0043269 {is_inferred="true"} ! regulation of ion transport
 is_a: GO:0051580 {is_inferred="true"} ! regulation of neurotransmitter uptake
 
 [Term]
 id: GO:0051617 ! negative regulation of histamine uptake
+is_a: GO:0043271 {is_inferred="true"} ! negative regulation of ion transport
 is_a: GO:0051581 {is_inferred="true"} ! negative regulation of neurotransmitter uptake
 is_a: GO:0051616 {is_inferred="true"} ! regulation of histamine uptake
 
 [Term]
 id: GO:0051618 ! positive regulation of histamine uptake
+is_a: GO:0043270 {is_inferred="true"} ! positive regulation of ion transport
 is_a: GO:0051582 {is_inferred="true"} ! positive regulation of neurotransmitter uptake
 is_a: GO:0051616 {is_inferred="true"} ! regulation of histamine uptake
 
@@ -46662,9 +47381,14 @@
 [Term]
 id: GO:0051870 ! methotrexate binding
 is_a: GO:0031406 {is_inferred="true"} ! carboxylic acid binding
+is_a: GO:0033218 {is_inferred="true"} ! amide binding
+is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
+is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
 
 [Term]
 id: GO:0051871 ! dihydrofolic acid binding
+is_a: GO:0031406 {is_inferred="true"} ! carboxylic acid binding
+is_a: GO:0033218 {is_inferred="true"} ! amide binding
 is_a: GO:0072341 {is_inferred="true"} ! modified amino acid binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
@@ -46831,11 +47555,12 @@
 [Term]
 id: GO:0051935 ! glutamate reuptake
 is_a: GO:0051933 {is_inferred="true"} ! amino acid neurotransmitter reuptake
-is_a: GO:1903802 {is_inferred="true"} ! L-glutamate(1-) import into cell
+is_a: GO:1990123 {is_inferred="true"} ! L-glutamate import into cell
 
 [Term]
 id: GO:0051936 ! gamma-aminobutyric acid reuptake
 is_a: GO:0051933 {is_inferred="true"} ! amino acid neurotransmitter reuptake
+is_a: GO:0051939 {is_inferred="true"} ! gamma-aminobutyric acid import
 
 [Term]
 id: GO:0051937 ! catecholamine transport
@@ -46844,12 +47569,13 @@
 
 [Term]
 id: GO:0051938 ! L-glutamate import
-is_a: GO:0043090 {is_inferred="true"} ! amino acid import
-is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:0015813 {is_inferred="true"} ! L-glutamate transport
+is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 
 [Term]
 id: GO:0051939 ! gamma-aminobutyric acid import
 is_a: GO:0015812 {is_inferred="true"} ! gamma-aminobutyric acid transport
+is_a: GO:0043090 {is_inferred="true"} ! amino acid import
 
 [Term]
 id: GO:0051940 ! regulation of catecholamine uptake involved in synaptic transmission
@@ -46932,20 +47658,24 @@
 [Term]
 id: GO:0051955 ! regulation of amino acid transport
 is_a: GO:0032890 {is_inferred="true"} ! regulation of organic acid transport
+is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
 
 [Term]
 id: GO:0051956 ! negative regulation of amino acid transport
 is_a: GO:0032891 {is_inferred="true"} ! negative regulation of organic acid transport
 is_a: GO:0051955 {is_inferred="true"} ! regulation of amino acid transport
+is_a: GO:1903792 {is_inferred="true"} ! negative regulation of anion transport
 
 [Term]
 id: GO:0051957 ! positive regulation of amino acid transport
 is_a: GO:0032892 {is_inferred="true"} ! positive regulation of organic acid transport
 is_a: GO:0051955 {is_inferred="true"} ! regulation of amino acid transport
+is_a: GO:1903793 {is_inferred="true"} ! positive regulation of anion transport
 
 [Term]
 id: GO:0051958 ! methotrexate transport
 is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
+is_a: GO:0042886 {is_inferred="true"} ! amide transport
 
 [Term]
 id: GO:0051960 ! regulation of nervous system development
@@ -47173,6 +47903,7 @@
 
 [Term]
 id: GO:0052573 ! UDP-D-galactose metabolic process
+is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
 is_a: GO:0009225 {is_inferred="true"} ! nucleotide-sugar metabolic process
 
 [Term]
@@ -47186,7 +47917,7 @@
 
 [Term]
 id: GO:0052644 ! chlorophyllide a metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 is_a: GO:0052643 {is_inferred="true"} ! chlorophyllide metabolic process
 
 [Term]
@@ -47215,6 +47946,7 @@
 id: GO:0052649 ! coenzyme gamma-F420-2 metabolic process
 is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
 is_a: GO:0052648 {is_inferred="true"} ! ribitol phosphate metabolic process
+is_a: GO:0072350 {is_inferred="true"} ! tricarboxylic acid metabolic process
 is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
 is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
 
@@ -47246,16 +47978,24 @@
 is_a: GO:0052698 {is_inferred="true"} ! ergothioneine metabolic process
 
 [Term]
-id: GO:0052704 ! ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine
-is_a: GO:0052805 {is_inferred="true"} ! imidazole-containing compound catabolic process
-is_a: GO:1901606 {is_inferred="true"} ! alpha-amino acid catabolic process
+id: GO:0052701 ! cellular modified histidine metabolic process
+is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 
 [Term]
+id: GO:0052702 ! cellular modified histidine catabolic process
+is_a: GO:0046395 {is_inferred="true"} ! carboxylic acid catabolic process
+
+[Term]
+id: GO:0052703 ! cellular modified histidine biosynthetic process
+is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
+
+[Term]
 id: GO:0052707 ! N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine
 is_a: GO:0052709 {is_inferred="true"} ! N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process
 
 [Term]
 id: GO:0052708 ! N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
 
 [Term]
@@ -47458,6 +48198,11 @@
 is_a: GO:0098722 {is_inferred="true"} ! asymmetric stem cell division
 
 [Term]
+id: GO:0055062 ! phosphate ion homeostasis
+is_a: GO:0055083 {is_inferred="true"} ! monovalent inorganic anion homeostasis
+is_a: GO:0072505 {is_inferred="true"} ! divalent inorganic anion homeostasis
+
+[Term]
 id: GO:0055065 ! metal ion homeostasis
 is_a: GO:0098771 {is_inferred="true"} ! inorganic ion homeostasis
 
@@ -47521,6 +48266,7 @@
 
 [Term]
 id: GO:0055089 ! fatty acid homeostasis
+is_a: GO:0055081 {is_inferred="true"} ! anion homeostasis
 is_a: GO:0055088 {is_inferred="true"} ! lipid homeostasis
 
 [Term]
@@ -47529,6 +48275,7 @@
 
 [Term]
 id: GO:0055091 ! phospholipid homeostasis
+is_a: GO:0055081 {is_inferred="true"} ! anion homeostasis
 is_a: GO:0055088 {is_inferred="true"} ! lipid homeostasis
 
 [Term]
@@ -47577,6 +48324,7 @@
 [Term]
 id: GO:0055130 ! D-alanine catabolic process
 is_a: GO:0006524 {is_inferred="true"} ! alanine catabolic process
+is_a: GO:0019478 {is_inferred="true"} ! D-amino acid catabolic process
 is_a: GO:0046436 {is_inferred="true"} ! D-alanine metabolic process
 
 [Term]
@@ -48334,7 +49082,7 @@
 
 [Term]
 id: GO:0060356 ! leucine import
-is_a: GO:0015803 {is_inferred="true"} ! branched-chain amino acid transport
+is_a: GO:0015820 {is_inferred="true"} ! leucine transport
 is_a: GO:0043090 {is_inferred="true"} ! amino acid import
 
 [Term]
@@ -50874,6 +51622,7 @@
 id: GO:0061507 ! cyclic-GMP-AMP binding
 is_a: GO:0032559 {is_inferred="true"} ! adenyl ribonucleotide binding
 is_a: GO:0032561 {is_inferred="true"} ! guanyl ribonucleotide binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
 [Term]
 id: GO:0061509 ! asymmetric protein localization to old mitotic spindle pole body
@@ -50907,17 +51656,20 @@
 
 [Term]
 id: GO:0061531 ! primary amine secretion
+is_a: GO:0015695 {is_inferred="true"} ! organic cation transport
+is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 is_a: GO:0015837 {is_inferred="true"} ! amine transport
 
 [Term]
 id: GO:0061536 ! glycine secretion
-is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
+is_a: GO:0015816 {is_inferred="true"} ! glycine transport
 is_a: GO:0046717 {is_inferred="true"} ! acid secretion
 
 [Term]
 id: GO:0061539 ! octopamine secretion
+is_a: GO:0015695 {is_inferred="true"} ! organic cation transport
+is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
 id: GO:0061545 ! tyramine secretion
@@ -51050,7 +51802,6 @@
 is_a: GO:0019637 {is_inferred="true"} ! organophosphate metabolic process
 is_a: GO:0042180 {is_inferred="true"} ! cellular ketone metabolic process
 is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
-is_a: GO:1901135 {is_inferred="true"} ! carbohydrate derivative metabolic process
 
 [Term]
 id: GO:0061721 ! 6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)
@@ -51058,7 +51809,6 @@
 is_a: GO:0019637 {is_inferred="true"} ! organophosphate metabolic process
 is_a: GO:0042180 {is_inferred="true"} ! cellular ketone metabolic process
 is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
-is_a: GO:1901135 {is_inferred="true"} ! carbohydrate derivative metabolic process
 
 [Term]
 id: GO:0061722 ! sulphoglycolysis
@@ -51212,7 +51962,7 @@
 
 [Term]
 id: GO:0070025 ! carbon monoxide binding
-is_a: GO:0005488 {is_inferred="true"} ! binding
+is_a: GO:0043169 {is_inferred="true"} ! cation binding
 
 [Term]
 id: GO:0070026 ! nitric oxide binding
@@ -51269,6 +52019,10 @@
 is_a: GO:0090277 {is_inferred="true"} ! positive regulation of peptide hormone secretion
 
 [Term]
+id: GO:0070095 ! fructose-6-phosphate binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
+
+[Term]
 id: GO:0070099 ! regulation of chemokine-mediated signaling pathway
 is_a: GO:0001959 {is_inferred="true"} ! regulation of cytokine-mediated signaling pathway
 
@@ -51519,7 +52273,12 @@
 is_a: GO:0070173 {is_inferred="true"} ! regulation of enamel mineralization
 
 [Term]
+id: GO:0070178 ! D-serine metabolic process
+is_a: GO:0046416 {is_inferred="true"} ! D-amino acid metabolic process
+
+[Term]
 id: GO:0070179 ! D-serine biosynthetic process
+is_a: GO:0046437 {is_inferred="true"} ! D-amino acid biosynthetic process
 is_a: GO:0070178 {is_inferred="true"} ! D-serine metabolic process
 
 [Term]
@@ -51711,6 +52470,7 @@
 [Term]
 id: GO:0070281 ! pyridoxamine binding
 is_a: GO:0070279 {is_inferred="true"} ! vitamin B6 binding
+is_a: GO:0070405 {is_inferred="true"} ! ammonium ion binding
 
 [Term]
 id: GO:0070282 ! pyridoxine binding
@@ -51747,7 +52507,7 @@
 
 [Term]
 id: GO:0070300 ! phosphatidic acid binding
-is_a: GO:0043168 {is_inferred="true"} ! anion binding
+is_a: GO:0005543 {is_inferred="true"} ! phospholipid binding
 
 [Term]
 id: GO:0070301 ! cellular response to hydrogen peroxide
@@ -51930,18 +52690,22 @@
 
 [Term]
 id: GO:0070401 ! NADP+ binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:0050661 {is_inferred="true"} ! NADP binding
 
 [Term]
 id: GO:0070402 ! NADPH binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:0050661 {is_inferred="true"} ! NADP binding
 
 [Term]
 id: GO:0070403 ! NAD+ binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:0051287 {is_inferred="true"} ! NAD binding
 
 [Term]
 id: GO:0070404 ! NADH binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:0051287 {is_inferred="true"} ! NAD binding
 
 [Term]
@@ -51951,6 +52715,7 @@
 [Term]
 id: GO:0070406 ! glutamine binding
 is_a: GO:0016597 {is_inferred="true"} ! amino acid binding
+is_a: GO:0043169 {is_inferred="true"} ! cation binding
 
 [Term]
 id: GO:0070408 ! carbamoyl phosphate metabolic process
@@ -52209,7 +52974,7 @@
 
 [Term]
 id: GO:0070538 ! oleic acid binding
-is_a: GO:0005504 {is_inferred="true"} ! fatty acid binding
+is_a: GO:0036041 {is_inferred="true"} ! long-chain fatty acid binding
 
 [Term]
 id: GO:0070539 ! linoleic acid binding
@@ -52217,8 +52982,7 @@
 
 [Term]
 id: GO:0070540 ! stearic acid binding
-is_a: GO:0008289 {is_inferred="true"} ! lipid binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
+is_a: GO:0036041 {is_inferred="true"} ! long-chain fatty acid binding
 
 [Term]
 id: GO:0070541 ! response to platinum ion
@@ -52232,8 +52996,7 @@
 
 [Term]
 id: GO:0070543 ! response to linoleic acid
-is_a: GO:0033993 {is_inferred="true"} ! response to lipid
-is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
+is_a: GO:0070542 {is_inferred="true"} ! response to fatty acid
 
 [Term]
 id: GO:0070558 ! alphaM-beta2 integrin-CD63 complex
@@ -52365,6 +53128,7 @@
 id: GO:0070616 ! regulation of thiamine diphosphate biosynthetic process
 is_a: GO:0019220 {is_inferred="true"} ! regulation of phosphate metabolic process
 is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
+is_a: GO:0042762 {is_inferred="true"} ! regulation of sulfur metabolic process
 is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
 is_a: GO:0051196 {is_inferred="true"} ! regulation of coenzyme metabolic process
 
@@ -52373,6 +53137,7 @@
 is_a: GO:0031327 {is_inferred="true"} ! negative regulation of cellular biosynthetic process
 is_a: GO:0045936 {is_inferred="true"} ! negative regulation of phosphate metabolic process
 is_a: GO:0051172 {is_inferred="true"} ! negative regulation of nitrogen compound metabolic process
+is_a: GO:0051175 {is_inferred="true"} ! negative regulation of sulfur metabolic process
 is_a: GO:0051198 {is_inferred="true"} ! negative regulation of coenzyme metabolic process
 is_a: GO:0070616 {is_inferred="true"} ! regulation of thiamine diphosphate biosynthetic process
 
@@ -52512,6 +53277,10 @@
 is_a: GO:0007032 {is_inferred="true"} ! endosome organization
 
 [Term]
+id: GO:0070679 ! inositol 1,4,5 trisphosphate binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
+
+[Term]
 id: GO:0070689 ! L-threonine catabolic process to propionate
 is_a: GO:0019541 {is_inferred="true"} ! propionate metabolic process
 
@@ -52551,6 +53320,7 @@
 [Term]
 id: GO:0070728 ! leucine binding
 is_a: GO:0016597 {is_inferred="true"} ! amino acid binding
+is_a: GO:0043169 {is_inferred="true"} ! cation binding
 
 [Term]
 id: GO:0070729 ! cyclic nucleotide transport
@@ -52558,6 +53328,7 @@
 
 [Term]
 id: GO:0070730 ! cAMP transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015868 {is_inferred="true"} ! purine ribonucleotide transport
 is_a: GO:0051503 {is_inferred="true"} ! adenine nucleotide transport
 is_a: GO:0070729 {is_inferred="true"} ! cyclic nucleotide transport
@@ -52565,6 +53336,7 @@
 [Term]
 id: GO:0070731 ! cGMP transport
 is_a: GO:0001408 {is_inferred="true"} ! guanine nucleotide transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015868 {is_inferred="true"} ! purine ribonucleotide transport
 is_a: GO:0070729 {is_inferred="true"} ! cyclic nucleotide transport
 
@@ -52644,6 +53416,7 @@
 [Term]
 id: GO:0070777 ! D-aspartate transport
 is_a: GO:0015810 {is_inferred="true"} ! aspartate transport
+is_a: GO:0042940 {is_inferred="true"} ! D-amino acid transport
 
 [Term]
 id: GO:0070778 ! L-aspartate transport
@@ -52652,6 +53425,7 @@
 
 [Term]
 id: GO:0070779 ! D-aspartate import
+is_a: GO:0043090 {is_inferred="true"} ! amino acid import
 is_a: GO:0070777 {is_inferred="true"} ! D-aspartate transport
 
 [Term]
@@ -52786,6 +53560,7 @@
 
 [Term]
 id: GO:0070811 ! glycerol-2-phosphate transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015748 {is_inferred="true"} ! organophosphate ester transport
 is_a: GO:1901264 {is_inferred="true"} ! carbohydrate derivative transport
 
@@ -52805,14 +53580,17 @@
 [Term]
 id: GO:0070832 ! phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline
 is_a: GO:0006656 {is_inferred="true"} ! phosphatidylcholine biosynthetic process
+is_a: GO:1901160 {is_inferred="true"} ! primary amino compound metabolic process
 
 [Term]
 id: GO:0070833 ! phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine
 is_a: GO:0006656 {is_inferred="true"} ! phosphatidylcholine biosynthetic process
+is_a: GO:1901160 {is_inferred="true"} ! primary amino compound metabolic process
 
 [Term]
 id: GO:0070834 ! phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine
 is_a: GO:0006656 {is_inferred="true"} ! phosphatidylcholine biosynthetic process
+is_a: GO:1901160 {is_inferred="true"} ! primary amino compound metabolic process
 
 [Term]
 id: GO:0070836 ! caveola assembly
@@ -52902,7 +53680,6 @@
 
 [Term]
 id: GO:0070881 ! regulation of proline transport
-is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
 is_a: GO:0051955 {is_inferred="true"} ! regulation of amino acid transport
 
 [Term]
@@ -52921,7 +53698,8 @@
 
 [Term]
 id: GO:0070890 ! sodium-dependent L-ascorbate transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0015145 {is_inferred="true"} ! monosaccharide transmembrane transporter activity
+is_a: GO:0046943 {is_inferred="true"} ! carboxylic acid transmembrane transporter activity
 is_a: GO:0090482 {is_inferred="true"} ! vitamin transmembrane transporter activity
 
 [Term]
@@ -52982,32 +53760,35 @@
 
 [Term]
 id: GO:0070905 ! serine binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
+is_a: GO:0016597 {is_inferred="true"} ! amino acid binding
+is_a: GO:0043169 {is_inferred="true"} ! cation binding
 
 [Term]
 id: GO:0070906 ! aspartate:alanine antiporter activity
-is_a: GO:0015297 {is_inferred="true"} ! antiporter activity
+is_a: GO:0015301 {is_inferred="true"} ! anion:anion antiporter activity
 is_a: GO:0015556 {is_inferred="true"} ! C4-dicarboxylate transmembrane transporter activity
 is_a: GO:0022858 {is_inferred="true"} ! alanine transmembrane transporter activity
 
 [Term]
 id: GO:0070907 ! histidine:histamine antiporter activity
+is_a: GO:0008519 {is_inferred="true"} ! ammonium transmembrane transporter activity
 is_a: GO:0015171 {is_inferred="true"} ! amino acid transmembrane transporter activity
-is_a: GO:0015297 {is_inferred="true"} ! antiporter activity
+is_a: GO:0015491 {is_inferred="true"} ! cation:cation antiporter activity
 is_a: GO:1901474 {is_inferred="true"} ! azole transmembrane transporter activity
 
 [Term]
 id: GO:0070908 ! tyrosine:tyramine antiporter activity
 is_a: GO:0008504 {is_inferred="true"} ! monoamine transmembrane transporter activity
+is_a: GO:0008519 {is_inferred="true"} ! ammonium transmembrane transporter activity
 is_a: GO:0015173 {is_inferred="true"} ! aromatic amino acid transmembrane transporter activity
-is_a: GO:0015297 {is_inferred="true"} ! antiporter activity
+is_a: GO:0015491 {is_inferred="true"} ! cation:cation antiporter activity
 is_a: GO:1901618 {is_inferred="true"} ! organic hydroxy compound transmembrane transporter activity
 
 [Term]
 id: GO:0070909 ! glutamate:gamma-aminobutyric acid antiporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0005310 {is_inferred="true"} ! dicarboxylic acid transmembrane transporter activity
 is_a: GO:0015185 {is_inferred="true"} ! gamma-aminobutyric acid transmembrane transporter activity
-is_a: GO:0015297 {is_inferred="true"} ! antiporter activity
+is_a: GO:0015301 {is_inferred="true"} ! anion:anion antiporter activity
 
 [Term]
 id: GO:0070910 ! cell wall macromolecule catabolic process involved in cell wall disassembly
@@ -53038,15 +53819,16 @@
 
 [Term]
 id: GO:0070926 ! regulation of ATP:ADP antiporter activity
-is_a: GO:0022898 {is_inferred="true"} ! regulation of transmembrane transporter activity
 is_a: GO:0032242 {is_inferred="true"} ! regulation of nucleoside transport
+is_a: GO:0032412 {is_inferred="true"} ! regulation of ion transmembrane transporter activity
+is_a: GO:1903959 {is_inferred="true"} ! regulation of anion transmembrane transport
 
 [Term]
 id: GO:0070927 ! negative regulation of ATP:ADP antiporter activity
 is_a: GO:0032243 {is_inferred="true"} ! negative regulation of nucleoside transport
-is_a: GO:0032410 {is_inferred="true"} ! negative regulation of transporter activity
-is_a: GO:0034763 {is_inferred="true"} ! negative regulation of transmembrane transport
+is_a: GO:0032413 {is_inferred="true"} ! negative regulation of ion transmembrane transporter activity
 is_a: GO:0070926 {is_inferred="true"} ! regulation of ATP:ADP antiporter activity
+is_a: GO:1903960 {is_inferred="true"} ! negative regulation of anion transmembrane transport
 
 [Term]
 id: GO:0070939 ! Dsl1/NZR complex
@@ -53158,6 +53940,7 @@
 
 [Term]
 id: GO:0070967 ! coenzyme F420 binding
+is_a: GO:0031406 {is_inferred="true"} ! carboxylic acid binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 is_a: GO:0097367 {is_inferred="true"} ! carbohydrate derivative binding
 is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
@@ -53165,6 +53948,9 @@
 [Term]
 id: GO:0070968 ! pyrroloquinoline quinone binding
 is_a: GO:0031406 {is_inferred="true"} ! carboxylic acid binding
+is_a: GO:0048038 {is_inferred="true"} ! quinone binding
+is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
+is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
 
 [Term]
 id: GO:0070972 ! protein localization to endoplasmic reticulum
@@ -53701,6 +54487,7 @@
 [Term]
 id: GO:0071246 ! cellular response to chlorate
 is_a: GO:0010157 {is_inferred="true"} ! response to chlorate
+is_a: GO:0071229 {is_inferred="true"} ! cellular response to acid chemical
 is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
 
 [Term]
@@ -53715,11 +54502,13 @@
 [Term]
 id: GO:0071249 ! cellular response to nitrate
 is_a: GO:0010167 {is_inferred="true"} ! response to nitrate
+is_a: GO:0071229 {is_inferred="true"} ! cellular response to acid chemical
 is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
 is_a: GO:1902170 {is_inferred="true"} ! cellular response to reactive nitrogen species
 
 [Term]
 id: GO:0071250 ! cellular response to nitrite
+is_a: GO:0071229 {is_inferred="true"} ! cellular response to acid chemical
 is_a: GO:0080033 {is_inferred="true"} ! response to nitrite
 is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
 is_a: GO:1902170 {is_inferred="true"} ! cellular response to reactive nitrogen species
@@ -53765,6 +54554,7 @@
 [Term]
 id: GO:0071272 ! morphine metabolic process
 is_a: GO:0033076 {is_inferred="true"} ! isoquinoline alkaloid metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 is_a: GO:1901376 {is_inferred="true"} ! organic heteropentacyclic compound metabolic process
 
 [Term]
@@ -53848,8 +54638,10 @@
 
 [Term]
 id: GO:0071298 ! cellular response to L-ascorbic acid
-is_a: GO:0010033 {is_inferred="true"} ! response to organic substance
-is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
+is_a: GO:0033591 {is_inferred="true"} ! response to L-ascorbic acid
+is_a: GO:0071229 {is_inferred="true"} ! cellular response to acid chemical
+is_a: GO:0071295 {is_inferred="true"} ! cellular response to vitamin
+is_a: GO:0071326 {is_inferred="true"} ! cellular response to monosaccharide stimulus
 
 [Term]
 id: GO:0071299 ! cellular response to vitamin A
@@ -53919,6 +54711,7 @@
 [Term]
 id: GO:0071311 ! cellular response to acetate
 is_a: GO:0010034 {is_inferred="true"} ! response to acetate
+is_a: GO:0071229 {is_inferred="true"} ! cellular response to acid chemical
 is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
 
 [Term]
@@ -53934,6 +54727,7 @@
 [Term]
 id: GO:0071314 ! cellular response to cocaine
 is_a: GO:0042220 {is_inferred="true"} ! response to cocaine
+is_a: GO:0071242 {is_inferred="true"} ! cellular response to ammonium ion
 is_a: GO:0071312 {is_inferred="true"} ! cellular response to alkaloid
 is_a: GO:0071407 {is_inferred="true"} ! cellular response to organic cyclic compound
 is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
@@ -53941,6 +54735,7 @@
 [Term]
 id: GO:0071315 ! cellular response to morphine
 is_a: GO:0043278 {is_inferred="true"} ! response to morphine
+is_a: GO:0071242 {is_inferred="true"} ! cellular response to ammonium ion
 is_a: GO:0071317 {is_inferred="true"} ! cellular response to isoquinoline alkaloid
 
 [Term]
@@ -54145,6 +54940,7 @@
 id: GO:0071379 ! cellular response to prostaglandin stimulus
 is_a: GO:0032870 {is_inferred="true"} ! cellular response to hormone stimulus
 is_a: GO:0034694 {is_inferred="true"} ! response to prostaglandin
+is_a: GO:0071398 {is_inferred="true"} ! cellular response to fatty acid
 
 [Term]
 id: GO:0071380 ! cellular response to prostaglandin E stimulus
@@ -54250,14 +55046,12 @@
 [Term]
 id: GO:0071399 ! cellular response to linoleic acid
 is_a: GO:0070543 {is_inferred="true"} ! response to linoleic acid
-is_a: GO:0071396 {is_inferred="true"} ! cellular response to lipid
-is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
+is_a: GO:0071398 {is_inferred="true"} ! cellular response to fatty acid
 
 [Term]
 id: GO:0071400 ! cellular response to oleic acid
 is_a: GO:0034201 {is_inferred="true"} ! response to oleic acid
-is_a: GO:0071396 {is_inferred="true"} ! cellular response to lipid
-is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
+is_a: GO:0071398 {is_inferred="true"} ! cellular response to fatty acid
 
 [Term]
 id: GO:0071401 ! cellular response to triglyceride
@@ -54340,6 +55134,7 @@
 [Term]
 id: GO:0071420 ! cellular response to histamine
 is_a: GO:0034776 {is_inferred="true"} ! response to histamine
+is_a: GO:0071242 {is_inferred="true"} ! cellular response to ammonium ion
 is_a: GO:0071407 {is_inferred="true"} ! cellular response to organic cyclic compound
 is_a: GO:0071417 {is_inferred="true"} ! cellular response to organonitrogen compound
 
@@ -54349,12 +55144,12 @@
 
 [Term]
 id: GO:0071422 ! succinate transmembrane transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
 id: GO:0071423 ! malate transmembrane transport
 is_a: GO:0015743 {is_inferred="true"} ! malate transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
 id: GO:0071425 ! hematopoietic stem cell proliferation
@@ -54456,11 +55251,14 @@
 
 [Term]
 id: GO:0071505 ! response to mycophenolic acid
-is_a: GO:0010033 {is_inferred="true"} ! response to organic substance
+is_a: GO:0001101 {is_inferred="true"} ! response to acid chemical
+is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
 [Term]
 id: GO:0071506 ! cellular response to mycophenolic acid
+is_a: GO:0071229 {is_inferred="true"} ! cellular response to acid chemical
+is_a: GO:0071407 {is_inferred="true"} ! cellular response to organic cyclic compound
 is_a: GO:0071505 {is_inferred="true"} ! response to mycophenolic acid
 is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
 
@@ -54507,17 +55305,17 @@
 
 [Term]
 id: GO:0071524 ! pyrrolysine biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
 is_a: GO:0042398 {is_inferred="true"} ! cellular modified amino acid biosynthetic process
 is_a: GO:0043604 {is_inferred="true"} ! amide biosynthetic process
+is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 is_a: GO:0071525 {is_inferred="true"} ! pyrrolysine metabolic process
 is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
 
 [Term]
 id: GO:0071525 ! pyrrolysine metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
 is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
+is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 is_a: GO:0043603 {is_inferred="true"} ! cellular amide metabolic process
 is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
 is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
@@ -54905,6 +55703,7 @@
 [Term]
 id: GO:0071715 ! icosanoid transport
 is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:1901571 {is_inferred="true"} ! fatty acid derivative transport
 
 [Term]
 id: GO:0071716 ! leukotriene transport
@@ -54966,12 +55765,13 @@
 id: GO:0071792 ! bacillithiol metabolic process
 is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
 is_a: GO:0016137 {is_inferred="true"} ! glycoside metabolic process
-is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
+is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 
 [Term]
 id: GO:0071793 ! bacillithiol biosynthetic process
 is_a: GO:0016138 {is_inferred="true"} ! glycoside biosynthetic process
 is_a: GO:0044272 {is_inferred="true"} ! sulfur compound biosynthetic process
+is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 is_a: GO:0071792 {is_inferred="true"} ! bacillithiol metabolic process
 
 [Term]
@@ -55899,6 +56699,10 @@
 is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 
 [Term]
+id: GO:0072334 ! UDP-galactose transmembrane transport
+is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+
+[Term]
 id: GO:0072335 ! regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation
 is_a: GO:0060828 {is_inferred="true"} ! regulation of canonical Wnt signaling pathway
 is_a: GO:1905292 {is_inferred="true"} ! regulation of neural crest cell differentiation
@@ -56341,12 +57145,13 @@
 
 [Term]
 id: GO:0072544 ! L-DOPA binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
+is_a: GO:0016597 {is_inferred="true"} ! amino acid binding
 is_a: GO:0072341 {is_inferred="true"} ! modified amino acid binding
 
 [Term]
 id: GO:0072545 ! tyrosine binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
+is_a: GO:0016597 {is_inferred="true"} ! amino acid binding
+is_a: GO:0043169 {is_inferred="true"} ! cation binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 
 [Term]
@@ -56360,6 +57165,7 @@
 
 [Term]
 id: GO:0072570 ! ADP-D-ribose binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 is_a: GO:0097367 {is_inferred="true"} ! carbohydrate derivative binding
 is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
@@ -56604,9 +57410,11 @@
 id: GO:0072733 ! response to staurosporine
 is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
 is_a: GO:0043279 {is_inferred="true"} ! response to alkaloid
+is_a: GO:0060359 {is_inferred="true"} ! response to ammonium ion
 
 [Term]
 id: GO:0072734 ! cellular response to staurosporine
+is_a: GO:0071242 {is_inferred="true"} ! cellular response to ammonium ion
 is_a: GO:0071312 {is_inferred="true"} ! cellular response to alkaloid
 is_a: GO:0071407 {is_inferred="true"} ! cellular response to organic cyclic compound
 is_a: GO:0072733 {is_inferred="true"} ! response to staurosporine
@@ -56631,6 +57439,7 @@
 
 [Term]
 id: GO:0072743 ! cellular response to erythromycin
+is_a: GO:0071242 {is_inferred="true"} ! cellular response to ammonium ion
 is_a: GO:0071407 {is_inferred="true"} ! cellular response to organic cyclic compound
 is_a: GO:1901323 {is_inferred="true"} ! response to erythromycin
 is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
@@ -57362,12 +58171,12 @@
 
 [Term]
 id: GO:0080024 ! indolebutyric acid metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 is_a: GO:0042430 {is_inferred="true"} ! indole-containing compound metabolic process
 
 [Term]
 id: GO:0080025 ! phosphatidylinositol-3,5-bisphosphate binding
-is_a: GO:0043168 {is_inferred="true"} ! anion binding
+is_a: GO:1902936 {is_inferred="true"} ! phosphatidylinositol bisphosphate binding
 
 [Term]
 id: GO:0080026 ! response to indolebutyric acid
@@ -57383,6 +58192,7 @@
 
 [Term]
 id: GO:0080033 ! response to nitrite
+is_a: GO:0001101 {is_inferred="true"} ! response to acid chemical
 is_a: GO:0010035 {is_inferred="true"} ! response to inorganic substance
 is_a: GO:1901698 {is_inferred="true"} ! response to nitrogen compound
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
@@ -57390,6 +58200,7 @@
 [Term]
 id: GO:0080035 ! 2-hydroxy-but-3-enyl glucosinolate biosynthetic process
 is_a: GO:0019761 {is_inferred="true"} ! glucosinolate biosynthetic process
+is_a: GO:1902653 {is_inferred="true"} ! secondary alcohol biosynthetic process
 
 [Term]
 id: GO:0080036 ! regulation of cytokinin-activated signaling pathway
@@ -57457,7 +58268,8 @@
 
 [Term]
 id: GO:0080094 ! response to trehalose-6-phosphate
-is_a: GO:0010033 {is_inferred="true"} ! response to organic substance
+is_a: GO:0046683 {is_inferred="true"} ! response to organophosphorus
+is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
 [Term]
 id: GO:0080111 ! DNA demethylation
@@ -57480,6 +58292,8 @@
 
 [Term]
 id: GO:0080121 ! AMP transport
+is_a: GO:0015695 {is_inferred="true"} ! organic cation transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015858 {is_inferred="true"} ! nucleoside transport
 is_a: GO:0015868 {is_inferred="true"} ! purine ribonucleotide transport
 is_a: GO:0051503 {is_inferred="true"} ! adenine nucleotide transport
@@ -57488,6 +58302,8 @@
 id: GO:0080122 ! AMP transmembrane transporter activity
 is_a: GO:0000295 {is_inferred="true"} ! adenine nucleotide transmembrane transporter activity
 is_a: GO:0005346 {is_inferred="true"} ! purine ribonucleotide transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0015101 {is_inferred="true"} ! organic cation transmembrane transporter activity
 is_a: GO:0015211 {is_inferred="true"} ! purine nucleoside transmembrane transporter activity
 
 [Term]
@@ -57534,10 +58350,11 @@
 
 [Term]
 id: GO:0080144 ! amino acid homeostasis
-is_a: GO:0048878 {is_inferred="true"} ! chemical homeostasis
+is_a: GO:0055081 {is_inferred="true"} ! anion homeostasis
 
 [Term]
 id: GO:0080145 ! cysteine homeostasis
+is_a: GO:0055080 {is_inferred="true"} ! cation homeostasis
 is_a: GO:0080144 {is_inferred="true"} ! amino acid homeostasis
 
 [Term]
@@ -57576,6 +58393,8 @@
 [Term]
 id: GO:0080168 ! abscisic acid transport
 is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
+is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
+is_a: GO:0046865 {is_inferred="true"} ! terpenoid transport
 
 [Term]
 id: GO:0080170 ! hydrogen peroxide transmembrane transport
@@ -57861,12 +58680,12 @@
 
 [Term]
 id: GO:0089703 ! L-aspartate transmembrane export from vacuole
-is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
+is_a: GO:0032974 {is_inferred="true"} ! amino acid transmembrane export from vacuole
 is_a: GO:0089712 {is_inferred="true"} ! L-aspartate transmembrane transport
 
 [Term]
 id: GO:0089704 ! L-glutamate transmembrane export from vacuole
-is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
+is_a: GO:0032974 {is_inferred="true"} ! amino acid transmembrane export from vacuole
 is_a: GO:0089711 {is_inferred="true"} ! L-glutamate transmembrane transport
 
 [Term]
@@ -57881,28 +58700,27 @@
 
 [Term]
 id: GO:0089707 ! L-lysine transmembrane export from vacuole
-is_a: GO:0032974 {is_inferred="true"} ! amino acid transmembrane export from vacuole
+is_a: GO:0034488 {is_inferred="true"} ! basic amino acid transmembrane export from vacuole
 is_a: GO:1903401 {is_inferred="true"} ! L-lysine transmembrane transport
 
 [Term]
 id: GO:0089708 ! L-histidine transmembrane export from vacuole
-is_a: GO:0032974 {is_inferred="true"} ! amino acid transmembrane export from vacuole
+is_a: GO:0034488 {is_inferred="true"} ! basic amino acid transmembrane export from vacuole
 is_a: GO:0089709 {is_inferred="true"} ! L-histidine transmembrane transport
 
 [Term]
 id: GO:0089709 ! L-histidine transmembrane transport
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 is_a: GO:1902024 {is_inferred="true"} ! L-histidine transport
 is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
 
 [Term]
 id: GO:0089711 ! L-glutamate transmembrane transport
-is_a: GO:0003333 {is_inferred="true"} ! amino acid transmembrane transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
 
 [Term]
 id: GO:0089712 ! L-aspartate transmembrane transport
-is_a: GO:0003333 {is_inferred="true"} ! amino acid transmembrane transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
 
 [Term]
 id: GO:0089718 ! amino acid import across plasma membrane
@@ -57912,12 +58730,13 @@
 
 [Term]
 id: GO:0089721 ! phosphoenolpyruvate transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0008028 {is_inferred="true"} ! monocarboxylic acid transmembrane transporter activity
+is_a: GO:0015605 {is_inferred="true"} ! organophosphate ester transmembrane transporter activity
 
 [Term]
 id: GO:0089722 ! phosphoenolpyruvate transmembrane transport
 is_a: GO:0015714 {is_inferred="true"} ! phosphoenolpyruvate transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
 id: GO:0090003 ! regulation of establishment of protein localization to plasma membrane
@@ -59239,11 +60058,11 @@
 
 [Term]
 id: GO:0090357 ! regulation of tryptophan metabolic process
-is_a: GO:0033238 {is_inferred="true"} ! regulation of cellular amine metabolic process
+is_a: GO:0006521 {is_inferred="true"} ! regulation of cellular amino acid metabolic process
 
 [Term]
 id: GO:0090358 ! positive regulation of tryptophan metabolic process
-is_a: GO:0033240 {is_inferred="true"} ! positive regulation of cellular amine metabolic process
+is_a: GO:0045764 {is_inferred="true"} ! positive regulation of cellular amino acid metabolic process
 is_a: GO:0090357 {is_inferred="true"} ! regulation of tryptophan metabolic process
 
 [Term]
@@ -59250,6 +60069,9 @@
 id: GO:0090359 ! negative regulation of abscisic acid biosynthetic process
 is_a: GO:0010115 {is_inferred="true"} ! regulation of abscisic acid biosynthetic process
 is_a: GO:0031327 {is_inferred="true"} ! negative regulation of cellular biosynthetic process
+is_a: GO:0045827 {is_inferred="true"} ! negative regulation of isoprenoid metabolic process
+is_a: GO:0051055 {is_inferred="true"} ! negative regulation of lipid biosynthetic process
+is_a: GO:1902931 {is_inferred="true"} ! negative regulation of alcohol biosynthetic process
 
 [Term]
 id: GO:0090361 ! regulation of platelet-derived growth factor production
@@ -59383,6 +60205,10 @@
 is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
 
 [Term]
+id: GO:0090422 ! thiamine pyrophosphate transporter activity
+is_a: GO:0045118 {is_inferred="true"} ! azole transporter activity
+
+[Term]
 id: GO:0090425 ! acinar cell differentiation
 is_a: GO:0002067 {is_inferred="true"} ! glandular epithelial cell differentiation
 
@@ -59409,6 +60235,8 @@
 
 [Term]
 id: GO:0090448 ! glucosinolate:proton symporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:1901505 {is_inferred="true"} ! carbohydrate derivative transporter activity
 is_a: GO:1901682 {is_inferred="true"} ! sulfur compound transmembrane transporter activity
 
 [Term]
@@ -59419,46 +60247,66 @@
 id: GO:0090453 ! aspartate transmembrane import into vacuole
 is_a: GO:0015810 {is_inferred="true"} ! aspartate transport
 is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:0044745 {is_inferred="true"} ! amino acid transmembrane import
 
 [Term]
 id: GO:0090454 ! glutamate transmembrane import into vacuole
 is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
 id: GO:0090455 ! ornithine transmembrane import into vacuole
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 
 [Term]
+id: GO:0090456 ! lysine transmembrane import into vacuole
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
+
+[Term]
+id: GO:0090457 ! histidine transmembrane import into vacuole
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
+
+[Term]
 id: GO:0090458 ! arginine transmembrane import into vacuole
 is_a: GO:1903826 {is_inferred="true"} ! arginine transmembrane transport
 
 [Term]
-id: GO:0090459 ! aspartate homeostasis
-is_a: GO:0055081 {is_inferred="true"} ! anion homeostasis
+id: GO:0090460 ! threonine homeostasis
+is_a: GO:0055080 {is_inferred="true"} ! cation homeostasis
 
 [Term]
-id: GO:0090461 ! glutamate homeostasis
-is_a: GO:0055081 {is_inferred="true"} ! anion homeostasis
+id: GO:0090462 ! ornithine homeostasis
+is_a: GO:0055080 {is_inferred="true"} ! cation homeostasis
 
 [Term]
+id: GO:0090463 ! lysine homeostasis
+is_a: GO:0055080 {is_inferred="true"} ! cation homeostasis
+
+[Term]
+id: GO:0090464 ! histidine homeostasis
+is_a: GO:0055080 {is_inferred="true"} ! cation homeostasis
+
+[Term]
+id: GO:0090465 ! arginine homeostasis
+is_a: GO:0055080 {is_inferred="true"} ! cation homeostasis
+
+[Term]
 id: GO:0090466 ! histidine import
+is_a: GO:0015817 {is_inferred="true"} ! histidine transport
 is_a: GO:0043090 {is_inferred="true"} ! amino acid import
-is_a: GO:0045117 {is_inferred="true"} ! azole transport
 
 [Term]
 id: GO:0090467 ! arginine import
+is_a: GO:0015809 {is_inferred="true"} ! arginine transport
 is_a: GO:0043090 {is_inferred="true"} ! amino acid import
 
 [Term]
 id: GO:0090468 ! valine import
-is_a: GO:0015803 {is_inferred="true"} ! branched-chain amino acid transport
+is_a: GO:0015829 {is_inferred="true"} ! valine transport
 is_a: GO:0043090 {is_inferred="true"} ! amino acid import
 
 [Term]
 id: GO:0090469 ! asparagine import
-is_a: GO:0042886 {is_inferred="true"} ! amide transport
+is_a: GO:0006867 {is_inferred="true"} ! asparagine transport
 is_a: GO:0043090 {is_inferred="true"} ! amino acid import
 
 [Term]
@@ -59478,6 +60326,7 @@
 
 [Term]
 id: GO:0090479 ! L-serine import
+is_a: GO:0015825 {is_inferred="true"} ! L-serine transport
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 is_a: GO:0090478 {is_inferred="true"} ! serine import
 
@@ -59521,6 +60370,7 @@
 
 [Term]
 id: GO:0090514 ! L-tyrosine transmembrane import into vacuole
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
 is_a: GO:1903808 {is_inferred="true"} ! L-tyrosine import into cell
 
@@ -59527,9 +60377,11 @@
 [Term]
 id: GO:0090515 ! L-glutamate transmembrane import into vacuole
 is_a: GO:0089711 {is_inferred="true"} ! L-glutamate transmembrane transport
+is_a: GO:1903802 {is_inferred="true"} ! L-glutamate(1-) import into cell
 
 [Term]
 id: GO:0090516 ! L-serine transmembrane import into vacuole
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
 is_a: GO:1903812 {is_inferred="true"} ! L-serine import into cell
 
@@ -59685,10 +60537,6 @@
 is_a: GO:1901606 {is_inferred="true"} ! alpha-amino acid catabolic process
 
 [Term]
-id: GO:0097054 ! L-glutamate biosynthetic process
-is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
-
-[Term]
 id: GO:0097055 ! agmatine biosynthetic process
 is_a: GO:1901162 {is_inferred="true"} ! primary amino compound biosynthetic process
 
@@ -59736,8 +60584,7 @@
 
 [Term]
 id: GO:0097089 ! methyl-branched fatty acid metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
-is_a: GO:0006629 {is_inferred="true"} ! lipid metabolic process
+is_a: GO:0006631 {is_inferred="true"} ! fatty acid metabolic process
 
 [Term]
 id: GO:0097092 ! polyacyltrehalose metabolic process
@@ -59799,6 +60646,7 @@
 
 [Term]
 id: GO:0097170 ! ADP-L-glycero-beta-D-manno-heptose metabolic process
+is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
 is_a: GO:0009225 {is_inferred="true"} ! nucleotide-sugar metabolic process
 
 [Term]
@@ -59808,10 +60656,12 @@
 
 [Term]
 id: GO:0097172 ! N-acetylmuramic acid metabolic process
+is_a: GO:0006040 {is_inferred="true"} ! amino sugar metabolic process
 is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 
 [Term]
 id: GO:0097173 ! N-acetylmuramic acid catabolic process
+is_a: GO:0046348 {is_inferred="true"} ! amino sugar catabolic process
 is_a: GO:0046395 {is_inferred="true"} ! carboxylic acid catabolic process
 is_a: GO:0097172 {is_inferred="true"} ! N-acetylmuramic acid metabolic process
 
@@ -59818,11 +60668,13 @@
 [Term]
 id: GO:0097174 ! 1,6-anhydro-N-acetyl-beta-muramic acid metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:1901135 {is_inferred="true"} ! carbohydrate derivative metabolic process
 
 [Term]
 id: GO:0097175 ! 1,6-anhydro-N-acetyl-beta-muramic acid catabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 is_a: GO:0097174 {is_inferred="true"} ! 1,6-anhydro-N-acetyl-beta-muramic acid metabolic process
+is_a: GO:1901136 {is_inferred="true"} ! carbohydrate derivative catabolic process
 
 [Term]
 id: GO:0097176 ! epoxide metabolic process
@@ -59833,11 +60685,13 @@
 
 [Term]
 id: GO:0097184 ! response to azide
-is_a: GO:0042221 {is_inferred="true"} ! response to chemical
+is_a: GO:0010035 {is_inferred="true"} ! response to inorganic substance
+is_a: GO:1901698 {is_inferred="true"} ! response to nitrogen compound
 
 [Term]
 id: GO:0097185 ! cellular response to azide
 is_a: GO:0097184 {is_inferred="true"} ! response to azide
+is_a: GO:1901699 {is_inferred="true"} ! cellular response to nitrogen compound
 
 [Term]
 id: GO:0097186 ! amelogenesis
@@ -59868,6 +60722,7 @@
 id: GO:0097216 ! guanosine tetraphosphate binding
 is_a: GO:0032550 {is_inferred="true"} ! purine ribonucleoside binding
 is_a: GO:0032561 {is_inferred="true"} ! guanyl ribonucleotide binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
 [Term]
 id: GO:0097222 ! mitochondrial mRNA polyadenylation
@@ -59894,6 +60749,7 @@
 
 [Term]
 id: GO:0097244 ! flavonol binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:0097243 {is_inferred="true"} ! flavonoid binding
 
 [Term]
@@ -59910,16 +60766,15 @@
 
 [Term]
 id: GO:0097251 ! leukotriene B4 biosynthetic process
-is_a: GO:0008610 {is_inferred="true"} ! lipid biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
+is_a: GO:0019370 {is_inferred="true"} ! leukotriene biosynthetic process
 is_a: GO:0036102 {is_inferred="true"} ! leukotriene B4 metabolic process
-is_a: GO:1901570 {is_inferred="true"} ! fatty acid derivative biosynthetic process
+is_a: GO:0042759 {is_inferred="true"} ! long-chain fatty acid biosynthetic process
 is_a: GO:1901617 {is_inferred="true"} ! organic hydroxy compound biosynthetic process
 
 [Term]
 id: GO:0097253 ! beta-hydroxybutyrate transmembrane transporter activity
-is_a: GO:0005319 {is_inferred="true"} ! lipid transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0015245 {is_inferred="true"} ! fatty acid transporter activity
+is_a: GO:0015665 {is_inferred="true"} ! alcohol transmembrane transporter activity
 
 [Term]
 id: GO:0097254 ! renal tubular secretion
@@ -60084,8 +60939,8 @@
 
 [Term]
 id: GO:0097339 ! glycolate transmembrane transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 is_a: GO:1900866 {is_inferred="true"} ! glycolate transport
+is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
 id: GO:0097342 ! ripoptosome
@@ -60766,12 +61621,13 @@
 [Term]
 id: GO:0098712 ! L-glutamate import across plasma membrane
 is_a: GO:0089711 {is_inferred="true"} ! L-glutamate transmembrane transport
-is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
+is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
 is_a: GO:1990123 {is_inferred="true"} ! L-glutamate import into cell
 
 [Term]
 id: GO:0098713 ! leucine import across plasma membrane
 is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 is_a: GO:1990122 {is_inferred="true"} ! leucine import into cell
 
 [Term]
@@ -60802,6 +61658,7 @@
 id: GO:0098718 ! serine import across plasma membrane
 is_a: GO:0061491 {is_inferred="true"} ! serine import into cell
 is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 
 [Term]
 id: GO:0098719 ! sodium ion import across plasma membrane
@@ -64277,6 +65134,7 @@
 [Term]
 id: GO:1900333 ! regulation of methane biosynthetic process from 3-(methylthio)propionic acid
 is_a: GO:0019217 {is_inferred="true"} ! regulation of fatty acid metabolic process
+is_a: GO:0042762 {is_inferred="true"} ! regulation of sulfur metabolic process
 is_a: GO:0043457 {is_inferred="true"} ! regulation of cellular respiration
 is_a: GO:1901577 {is_inferred="true"} ! regulation of alkane biosynthetic process
 
@@ -64283,6 +65141,7 @@
 [Term]
 id: GO:1900334 ! negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid
 is_a: GO:0045922 {is_inferred="true"} ! negative regulation of fatty acid metabolic process
+is_a: GO:0051175 {is_inferred="true"} ! negative regulation of sulfur metabolic process
 is_a: GO:1900333 {is_inferred="true"} ! regulation of methane biosynthetic process from 3-(methylthio)propionic acid
 is_a: GO:1901578 {is_inferred="true"} ! negative regulation of alkane biosynthetic process
 is_a: GO:1901856 {is_inferred="true"} ! negative regulation of cellular respiration
@@ -64290,6 +65149,7 @@
 [Term]
 id: GO:1900335 ! positive regulation of methane biosynthetic process from 3-(methylthio)propionic acid
 is_a: GO:0045923 {is_inferred="true"} ! positive regulation of fatty acid metabolic process
+is_a: GO:0051176 {is_inferred="true"} ! positive regulation of sulfur metabolic process
 is_a: GO:1900333 {is_inferred="true"} ! regulation of methane biosynthetic process from 3-(methylthio)propionic acid
 is_a: GO:1901579 {is_inferred="true"} ! positive regulation of alkane biosynthetic process
 is_a: GO:1901857 {is_inferred="true"} ! positive regulation of cellular respiration
@@ -65107,6 +65967,7 @@
 
 [Term]
 id: GO:1900495 ! negative regulation of butyryl-CoA biosynthetic process from acetyl-CoA
+is_a: GO:0010563 {is_inferred="true"} ! negative regulation of phosphorus metabolic process
 is_a: GO:0045717 {is_inferred="true"} ! negative regulation of fatty acid biosynthetic process
 is_a: GO:0051175 {is_inferred="true"} ! negative regulation of sulfur metabolic process
 is_a: GO:0051198 {is_inferred="true"} ! negative regulation of coenzyme metabolic process
@@ -65114,6 +65975,7 @@
 
 [Term]
 id: GO:1900496 ! positive regulation of butyryl-CoA biosynthetic process from acetyl-CoA
+is_a: GO:0010562 {is_inferred="true"} ! positive regulation of phosphorus metabolic process
 is_a: GO:0045723 {is_inferred="true"} ! positive regulation of fatty acid biosynthetic process
 is_a: GO:0051176 {is_inferred="true"} ! positive regulation of sulfur metabolic process
 is_a: GO:0051197 {is_inferred="true"} ! positive regulation of coenzyme metabolic process
@@ -65125,11 +65987,13 @@
 is_a: GO:0031329 {is_inferred="true"} ! regulation of cellular catabolic process
 is_a: GO:0042762 {is_inferred="true"} ! regulation of sulfur metabolic process
 is_a: GO:0050994 {is_inferred="true"} ! regulation of lipid catabolic process
+is_a: GO:0051174 {is_inferred="true"} ! regulation of phosphorus metabolic process
 is_a: GO:0051196 {is_inferred="true"} ! regulation of coenzyme metabolic process
 is_a: GO:1902930 {is_inferred="true"} ! regulation of alcohol biosynthetic process
 
 [Term]
 id: GO:1900498 ! negative regulation of butyryl-CoA catabolic process to butanol
+is_a: GO:0010563 {is_inferred="true"} ! negative regulation of phosphorus metabolic process
 is_a: GO:0031330 {is_inferred="true"} ! negative regulation of cellular catabolic process
 is_a: GO:0045922 {is_inferred="true"} ! negative regulation of fatty acid metabolic process
 is_a: GO:0050995 {is_inferred="true"} ! negative regulation of lipid catabolic process
@@ -65140,6 +66004,7 @@
 
 [Term]
 id: GO:1900499 ! positive regulation of butyryl-CoA catabolic process to butanol
+is_a: GO:0010562 {is_inferred="true"} ! positive regulation of phosphorus metabolic process
 is_a: GO:0031331 {is_inferred="true"} ! positive regulation of cellular catabolic process
 is_a: GO:0045923 {is_inferred="true"} ! positive regulation of fatty acid metabolic process
 is_a: GO:0050996 {is_inferred="true"} ! positive regulation of lipid catabolic process
@@ -65154,10 +66019,12 @@
 is_a: GO:0042304 {is_inferred="true"} ! regulation of fatty acid biosynthetic process
 is_a: GO:0042762 {is_inferred="true"} ! regulation of sulfur metabolic process
 is_a: GO:0050994 {is_inferred="true"} ! regulation of lipid catabolic process
+is_a: GO:0051174 {is_inferred="true"} ! regulation of phosphorus metabolic process
 is_a: GO:0051196 {is_inferred="true"} ! regulation of coenzyme metabolic process
 
 [Term]
 id: GO:1900501 ! negative regulation of butyryl-CoA catabolic process to butyrate
+is_a: GO:0010563 {is_inferred="true"} ! negative regulation of phosphorus metabolic process
 is_a: GO:0031330 {is_inferred="true"} ! negative regulation of cellular catabolic process
 is_a: GO:0045717 {is_inferred="true"} ! negative regulation of fatty acid biosynthetic process
 is_a: GO:0050995 {is_inferred="true"} ! negative regulation of lipid catabolic process
@@ -65167,6 +66034,7 @@
 
 [Term]
 id: GO:1900502 ! positive regulation of butyryl-CoA catabolic process to butyrate
+is_a: GO:0010562 {is_inferred="true"} ! positive regulation of phosphorus metabolic process
 is_a: GO:0031331 {is_inferred="true"} ! positive regulation of cellular catabolic process
 is_a: GO:0045723 {is_inferred="true"} ! positive regulation of fatty acid biosynthetic process
 is_a: GO:0050996 {is_inferred="true"} ! positive regulation of lipid catabolic process
@@ -65295,33 +66163,30 @@
 
 [Term]
 id: GO:1900533 ! palmitic acid metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
-is_a: GO:0006629 {is_inferred="true"} ! lipid metabolic process
+is_a: GO:0001676 {is_inferred="true"} ! long-chain fatty acid metabolic process
 
 [Term]
 id: GO:1900534 ! palmitic acid catabolic process
-is_a: GO:0016042 {is_inferred="true"} ! lipid catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
+is_a: GO:0042758 {is_inferred="true"} ! long-chain fatty acid catabolic process
 is_a: GO:1900533 {is_inferred="true"} ! palmitic acid metabolic process
 
 [Term]
 id: GO:1900535 ! palmitic acid biosynthetic process
-is_a: GO:0008610 {is_inferred="true"} ! lipid biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
+is_a: GO:0042759 {is_inferred="true"} ! long-chain fatty acid biosynthetic process
 is_a: GO:1900533 {is_inferred="true"} ! palmitic acid metabolic process
 
 [Term]
 id: GO:1900539 ! fumonisin metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 
 [Term]
 id: GO:1900540 ! fumonisin catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
+is_a: GO:0046395 {is_inferred="true"} ! carboxylic acid catabolic process
 is_a: GO:1900539 {is_inferred="true"} ! fumonisin metabolic process
 
 [Term]
 id: GO:1900541 ! fumonisin biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
+is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 is_a: GO:1900539 {is_inferred="true"} ! fumonisin metabolic process
 
 [Term]
@@ -65458,6 +66323,7 @@
 is_a: GO:0035836 {is_inferred="true"} ! ergot alkaloid metabolic process
 is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
 is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
 
 [Term]
@@ -65480,6 +66346,7 @@
 id: GO:1900567 ! chanoclavine-I aldehyde metabolic process
 is_a: GO:0006081 {is_inferred="true"} ! cellular aldehyde metabolic process
 is_a: GO:0035836 {is_inferred="true"} ! ergot alkaloid metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
 
 [Term]
@@ -65533,15 +66400,15 @@
 
 [Term]
 id: GO:1900576 ! gerfelin metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
 is_a: GO:0009712 {is_inferred="true"} ! catechol-containing compound metabolic process
 is_a: GO:0018904 {is_inferred="true"} ! ether metabolic process
+is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 
 [Term]
 id: GO:1900577 ! gerfelin catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
 is_a: GO:0019614 {is_inferred="true"} ! catechol-containing compound catabolic process
+is_a: GO:0046395 {is_inferred="true"} ! carboxylic acid catabolic process
 is_a: GO:1900576 {is_inferred="true"} ! gerfelin metabolic process
 is_a: GO:1901502 {is_inferred="true"} ! ether catabolic process
 
@@ -65548,7 +66415,7 @@
 [Term]
 id: GO:1900578 ! gerfelin biosynthetic process
 is_a: GO:0009713 {is_inferred="true"} ! catechol-containing compound biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
+is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 is_a: GO:1900576 {is_inferred="true"} ! gerfelin metabolic process
 is_a: GO:1901503 {is_inferred="true"} ! ether biosynthetic process
 
@@ -65574,20 +66441,20 @@
 
 [Term]
 id: GO:1900582 ! o-orsellinic acid metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
 is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 
 [Term]
 id: GO:1900583 ! o-orsellinic acid catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
 is_a: GO:0019336 {is_inferred="true"} ! phenol-containing compound catabolic process
+is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 is_a: GO:1900582 {is_inferred="true"} ! o-orsellinic acid metabolic process
 
 [Term]
 id: GO:1900584 ! o-orsellinic acid biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
+is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 is_a: GO:1900582 {is_inferred="true"} ! o-orsellinic acid metabolic process
 
 [Term]
@@ -65684,21 +66551,21 @@
 
 [Term]
 id: GO:1900600 ! endocrocin metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
 is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 is_a: GO:1901661 {is_inferred="true"} ! quinone metabolic process
 
 [Term]
 id: GO:1900601 ! endocrocin catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
 is_a: GO:0019336 {is_inferred="true"} ! phenol-containing compound catabolic process
+is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 is_a: GO:1900600 {is_inferred="true"} ! endocrocin metabolic process
 is_a: GO:1901662 {is_inferred="true"} ! quinone catabolic process
 
 [Term]
 id: GO:1900602 ! endocrocin biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
+is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 is_a: GO:1900600 {is_inferred="true"} ! endocrocin metabolic process
 is_a: GO:1901663 {is_inferred="true"} ! quinone biosynthetic process
 
@@ -65725,7 +66592,7 @@
 
 [Term]
 id: GO:1900606 ! tensidol B metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
 is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
 is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
@@ -65732,7 +66599,7 @@
 
 [Term]
 id: GO:1900607 ! tensidol B catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
+is_a: GO:0046395 {is_inferred="true"} ! carboxylic acid catabolic process
 is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
 is_a: GO:1900606 {is_inferred="true"} ! tensidol B metabolic process
 is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
@@ -65740,8 +66607,8 @@
 
 [Term]
 id: GO:1900608 ! tensidol B biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
+is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 is_a: GO:1900606 {is_inferred="true"} ! tensidol B metabolic process
 is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
 is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
@@ -66522,19 +67389,23 @@
 
 [Term]
 id: GO:1900751 ! 4-(trimethylammonio)butanoate transport
+is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 is_a: GO:0015838 {is_inferred="true"} ! amino-acid betaine transport
 
 [Term]
 id: GO:1900752 ! malonic acid transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
+is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
 
 [Term]
 id: GO:1900753 ! doxorubicin transport
+is_a: GO:0015695 {is_inferred="true"} ! organic cation transport
+is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 is_a: GO:1901656 {is_inferred="true"} ! glycoside transport
 
 [Term]
 id: GO:1900754 ! 4-hydroxyphenylacetate transport
 is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
+is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
 
 [Term]
 id: GO:1900756 ! protein processing in phagocytic vesicle
@@ -66806,21 +67677,21 @@
 
 [Term]
 id: GO:1900800 ! cspyrone B1 metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 is_a: GO:0042180 {is_inferred="true"} ! cellular ketone metabolic process
 is_a: GO:1901334 {is_inferred="true"} ! lactone metabolic process
 
 [Term]
 id: GO:1900801 ! cspyrone B1 catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
 is_a: GO:0042182 {is_inferred="true"} ! ketone catabolic process
+is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 is_a: GO:1900800 {is_inferred="true"} ! cspyrone B1 metabolic process
 is_a: GO:1901335 {is_inferred="true"} ! lactone catabolic process
 
 [Term]
 id: GO:1900802 ! cspyrone B1 biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0042181 {is_inferred="true"} ! ketone biosynthetic process
+is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 is_a: GO:1900800 {is_inferred="true"} ! cspyrone B1 metabolic process
 is_a: GO:1901336 {is_inferred="true"} ! lactone biosynthetic process
 
@@ -66851,6 +67722,7 @@
 [Term]
 id: GO:1900807 ! fumigaclavine C metabolic process
 is_a: GO:0035836 {is_inferred="true"} ! ergot alkaloid metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 is_a: GO:1900619 {is_inferred="true"} ! acetate ester metabolic process
 
 [Term]
@@ -66866,49 +67738,49 @@
 
 [Term]
 id: GO:1900810 ! helvolic acid metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
 is_a: GO:0008202 {is_inferred="true"} ! steroid metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 is_a: GO:0042180 {is_inferred="true"} ! cellular ketone metabolic process
 
 [Term]
 id: GO:1900811 ! helvolic acid catabolic process
 is_a: GO:0006706 {is_inferred="true"} ! steroid catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
 is_a: GO:0042182 {is_inferred="true"} ! ketone catabolic process
+is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 is_a: GO:1900810 {is_inferred="true"} ! helvolic acid metabolic process
 
 [Term]
 id: GO:1900812 ! helvolic acid biosynthetic process
 is_a: GO:0006694 {is_inferred="true"} ! steroid biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0042181 {is_inferred="true"} ! ketone biosynthetic process
+is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 is_a: GO:1900810 {is_inferred="true"} ! helvolic acid metabolic process
 
 [Term]
 id: GO:1900813 ! monodictyphenone metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
 is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 is_a: GO:0042180 {is_inferred="true"} ! cellular ketone metabolic process
 is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 
 [Term]
 id: GO:1900814 ! monodictyphenone catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
 is_a: GO:0019336 {is_inferred="true"} ! phenol-containing compound catabolic process
 is_a: GO:0042182 {is_inferred="true"} ! ketone catabolic process
+is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 is_a: GO:1900813 {is_inferred="true"} ! monodictyphenone metabolic process
 
 [Term]
 id: GO:1900815 ! monodictyphenone biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0042181 {is_inferred="true"} ! ketone biosynthetic process
 is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
+is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 is_a: GO:1900813 {is_inferred="true"} ! monodictyphenone metabolic process
 
 [Term]
 id: GO:1900816 ! ochratoxin A metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
 is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
+is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 is_a: GO:0043603 {is_inferred="true"} ! cellular amide metabolic process
 is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
 is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
@@ -66915,8 +67787,8 @@
 
 [Term]
 id: GO:1900817 ! ochratoxin A catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
 is_a: GO:0042219 {is_inferred="true"} ! cellular modified amino acid catabolic process
+is_a: GO:0046395 {is_inferred="true"} ! carboxylic acid catabolic process
 is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
 is_a: GO:1900816 {is_inferred="true"} ! ochratoxin A metabolic process
 is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
@@ -66923,10 +67795,10 @@
 
 [Term]
 id: GO:1900818 ! ochratoxin A biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
 is_a: GO:0042398 {is_inferred="true"} ! cellular modified amino acid biosynthetic process
 is_a: GO:0043604 {is_inferred="true"} ! amide biosynthetic process
+is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 is_a: GO:1900816 {is_inferred="true"} ! ochratoxin A metabolic process
 is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
 
@@ -66991,33 +67863,36 @@
 [Term]
 id: GO:1900828 ! D-tyrosine metabolic process
 is_a: GO:0006570 {is_inferred="true"} ! tyrosine metabolic process
+is_a: GO:0046416 {is_inferred="true"} ! D-amino acid metabolic process
 
 [Term]
 id: GO:1900829 ! D-tyrosine catabolic process
 is_a: GO:0006572 {is_inferred="true"} ! tyrosine catabolic process
+is_a: GO:0019478 {is_inferred="true"} ! D-amino acid catabolic process
 is_a: GO:1900828 {is_inferred="true"} ! D-tyrosine metabolic process
 
 [Term]
 id: GO:1900830 ! D-tyrosine biosynthetic process
 is_a: GO:0006571 {is_inferred="true"} ! tyrosine biosynthetic process
+is_a: GO:0046437 {is_inferred="true"} ! D-amino acid biosynthetic process
 is_a: GO:1900828 {is_inferred="true"} ! D-tyrosine metabolic process
 
 [Term]
 id: GO:1900831 ! D-leucine metabolic process
-is_a: GO:0009081 {is_inferred="true"} ! branched-chain amino acid metabolic process
-is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
+is_a: GO:0006551 {is_inferred="true"} ! leucine metabolic process
+is_a: GO:0046416 {is_inferred="true"} ! D-amino acid metabolic process
 
 [Term]
 id: GO:1900832 ! D-leucine catabolic process
-is_a: GO:0009083 {is_inferred="true"} ! branched-chain amino acid catabolic process
+is_a: GO:0006552 {is_inferred="true"} ! leucine catabolic process
+is_a: GO:0019478 {is_inferred="true"} ! D-amino acid catabolic process
 is_a: GO:1900831 {is_inferred="true"} ! D-leucine metabolic process
-is_a: GO:1901606 {is_inferred="true"} ! alpha-amino acid catabolic process
 
 [Term]
 id: GO:1900833 ! D-leucine biosynthetic process
-is_a: GO:0009082 {is_inferred="true"} ! branched-chain amino acid biosynthetic process
+is_a: GO:0009098 {is_inferred="true"} ! leucine biosynthetic process
+is_a: GO:0046437 {is_inferred="true"} ! D-amino acid biosynthetic process
 is_a: GO:1900831 {is_inferred="true"} ! D-leucine metabolic process
-is_a: GO:1901607 {is_inferred="true"} ! alpha-amino acid biosynthetic process
 
 [Term]
 id: GO:1900834 ! regulation of emericellin biosynthetic process
@@ -67210,23 +68085,29 @@
 [Term]
 id: GO:1900866 ! glycolate transport
 is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
+is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
 
 [Term]
 id: GO:1900867 ! sarcinapterin metabolic process
+is_a: GO:0072350 {is_inferred="true"} ! tricarboxylic acid metabolic process
 is_a: GO:2001115 {is_inferred="true"} ! methanopterin-containing compound metabolic process
 
 [Term]
 id: GO:1900868 ! sarcinapterin biosynthetic process
+is_a: GO:0072351 {is_inferred="true"} ! tricarboxylic acid biosynthetic process
 is_a: GO:1900867 {is_inferred="true"} ! sarcinapterin metabolic process
 is_a: GO:2001116 {is_inferred="true"} ! methanopterin-containing compound biosynthetic process
 
 [Term]
 id: GO:1900869 ! tatiopterin metabolic process
+is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
+is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 is_a: GO:0042558 {is_inferred="true"} ! pteridine-containing compound metabolic process
 
 [Term]
 id: GO:1900870 ! tatiopterin biosynthetic process
 is_a: GO:0042559 {is_inferred="true"} ! pteridine-containing compound biosynthetic process
+is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 is_a: GO:1900869 {is_inferred="true"} ! tatiopterin metabolic process
 
 [Term]
@@ -67482,20 +68363,18 @@
 
 [Term]
 id: GO:1900920 ! regulation of L-glutamate import
+is_a: GO:0002036 {is_inferred="true"} ! regulation of L-glutamate transport
 is_a: GO:0010958 {is_inferred="true"} ! regulation of amino acid import
-is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
 
 [Term]
 id: GO:1900921 ! negative regulation of L-glutamate import
-is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
+is_a: GO:0002037 {is_inferred="true"} ! negative regulation of L-glutamate transport
 is_a: GO:1900920 {is_inferred="true"} ! regulation of L-glutamate import
-is_a: GO:1903792 {is_inferred="true"} ! negative regulation of anion transport
 
 [Term]
 id: GO:1900922 ! positive regulation of L-glutamate import
-is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
+is_a: GO:0002038 {is_inferred="true"} ! positive regulation of L-glutamate transport
 is_a: GO:1900920 {is_inferred="true"} ! regulation of L-glutamate import
-is_a: GO:1903793 {is_inferred="true"} ! positive regulation of anion transport
 
 [Term]
 id: GO:1900923 ! regulation of glycine import
@@ -67805,18 +68684,18 @@
 
 [Term]
 id: GO:1900977 ! regulation of tatiopterin metabolic process
-is_a: GO:0031323 {is_inferred="true"} ! regulation of cellular metabolic process
 is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
+is_a: GO:0051174 {is_inferred="true"} ! regulation of phosphorus metabolic process
 
 [Term]
 id: GO:1900978 ! negative regulation of tatiopterin metabolic process
-is_a: GO:0031324 {is_inferred="true"} ! negative regulation of cellular metabolic process
+is_a: GO:0010563 {is_inferred="true"} ! negative regulation of phosphorus metabolic process
 is_a: GO:0051172 {is_inferred="true"} ! negative regulation of nitrogen compound metabolic process
 is_a: GO:1900977 {is_inferred="true"} ! regulation of tatiopterin metabolic process
 
 [Term]
 id: GO:1900979 ! positive regulation of tatiopterin metabolic process
-is_a: GO:0031325 {is_inferred="true"} ! positive regulation of cellular metabolic process
+is_a: GO:0010562 {is_inferred="true"} ! positive regulation of phosphorus metabolic process
 is_a: GO:0051173 {is_inferred="true"} ! positive regulation of nitrogen compound metabolic process
 is_a: GO:1900977 {is_inferred="true"} ! regulation of tatiopterin metabolic process
 
@@ -67841,6 +68720,7 @@
 id: GO:1900983 ! vindoline metabolic process
 is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
 is_a: GO:0046447 {is_inferred="true"} ! terpenoid indole alkaloid metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 is_a: GO:1900619 {is_inferred="true"} ! acetate ester metabolic process
 is_a: GO:1901376 {is_inferred="true"} ! organic heteropentacyclic compound metabolic process
 is_a: GO:1902644 {is_inferred="true"} ! tertiary alcohol metabolic process
@@ -67863,6 +68743,7 @@
 [Term]
 id: GO:1900986 ! ajmaline metabolic process
 is_a: GO:0046447 {is_inferred="true"} ! terpenoid indole alkaloid metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 
 [Term]
 id: GO:1900987 ! ajmaline catabolic process
@@ -67877,6 +68758,7 @@
 [Term]
 id: GO:1900989 ! scopolamine metabolic process
 is_a: GO:0046448 {is_inferred="true"} ! tropane alkaloid metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 is_a: GO:0097176 {is_inferred="true"} ! epoxide metabolic process
 
 [Term]
@@ -67997,6 +68879,7 @@
 [Term]
 id: GO:1901010 ! (S)-reticuline metabolic process
 is_a: GO:0046445 {is_inferred="true"} ! benzyl isoquinoline alkaloid metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 
 [Term]
 id: GO:1901011 ! (S)-reticuline catabolic process
@@ -68011,6 +68894,7 @@
 [Term]
 id: GO:1901013 ! 3alpha(S)-strictosidine metabolic process
 is_a: GO:0035834 {is_inferred="true"} ! indole alkaloid metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 is_a: GO:1901804 {is_inferred="true"} ! beta-glucoside metabolic process
 
 [Term]
@@ -68063,15 +68947,18 @@
 
 [Term]
 id: GO:1901022 ! 4-hydroxyphenylacetate metabolic process
+is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 
 [Term]
 id: GO:1901023 ! 4-hydroxyphenylacetate catabolic process
+is_a: GO:0019336 {is_inferred="true"} ! phenol-containing compound catabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 is_a: GO:1901022 {is_inferred="true"} ! 4-hydroxyphenylacetate metabolic process
 
 [Term]
 id: GO:1901024 ! 4-hydroxyphenylacetate biosynthetic process
+is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 is_a: GO:1901022 {is_inferred="true"} ! 4-hydroxyphenylacetate metabolic process
 
@@ -68125,16 +69012,17 @@
 [Term]
 id: GO:1901034 ! regulation of L-glutamine import
 is_a: GO:0010958 {is_inferred="true"} ! regulation of amino acid import
+is_a: GO:2000485 {is_inferred="true"} ! regulation of glutamine transport
 
 [Term]
 id: GO:1901035 ! negative regulation of L-glutamine import
-is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
 is_a: GO:1901034 {is_inferred="true"} ! regulation of L-glutamine import
+is_a: GO:2000486 {is_inferred="true"} ! negative regulation of glutamine transport
 
 [Term]
 id: GO:1901036 ! positive regulation of L-glutamine import
-is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
 is_a: GO:1901034 {is_inferred="true"} ! regulation of L-glutamine import
+is_a: GO:2000487 {is_inferred="true"} ! positive regulation of glutamine transport
 
 [Term]
 id: GO:1901038 ! cyanidin 3-O-glucoside metabolic process
@@ -68222,6 +69110,7 @@
 
 [Term]
 id: GO:1901055 ! trimethylenediamine metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
 
 [Term]
@@ -68278,8 +69167,10 @@
 
 [Term]
 id: GO:1901067 ! ferulate catabolic process
+is_a: GO:0019336 {is_inferred="true"} ! phenol-containing compound catabolic process
 is_a: GO:0033494 {is_inferred="true"} ! ferulate metabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
+is_a: GO:1901502 {is_inferred="true"} ! ether catabolic process
 
 [Term]
 id: GO:1901068 ! guanosine-containing compound metabolic process
@@ -68488,17 +69379,17 @@
 
 [Term]
 id: GO:1901110 ! actinorhodin metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
 is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
 is_a: GO:0030638 {is_inferred="true"} ! polyketide metabolic process
+is_a: GO:0043648 {is_inferred="true"} ! dicarboxylic acid metabolic process
 is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
 is_a: GO:1901661 {is_inferred="true"} ! quinone metabolic process
 
 [Term]
 id: GO:1901111 ! actinorhodin catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
 is_a: GO:0019336 {is_inferred="true"} ! phenol-containing compound catabolic process
 is_a: GO:0030640 {is_inferred="true"} ! polyketide catabolic process
+is_a: GO:0043649 {is_inferred="true"} ! dicarboxylic acid catabolic process
 is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
 is_a: GO:1901110 {is_inferred="true"} ! actinorhodin metabolic process
 is_a: GO:1901662 {is_inferred="true"} ! quinone catabolic process
@@ -68505,9 +69396,9 @@
 
 [Term]
 id: GO:1901112 ! actinorhodin biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
 is_a: GO:0030639 {is_inferred="true"} ! polyketide biosynthetic process
+is_a: GO:0043650 {is_inferred="true"} ! dicarboxylic acid biosynthetic process
 is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
 is_a: GO:1901110 {is_inferred="true"} ! actinorhodin metabolic process
 is_a: GO:1901663 {is_inferred="true"} ! quinone biosynthetic process
@@ -68515,6 +69406,7 @@
 [Term]
 id: GO:1901113 ! erythromycin metabolic process
 is_a: GO:0033067 {is_inferred="true"} ! macrolide metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 
 [Term]
 id: GO:1901114 ! erythromycin catabolic process
@@ -68548,6 +69440,7 @@
 id: GO:1901119 ! tobramycin metabolic process
 is_a: GO:0016137 {is_inferred="true"} ! glycoside metabolic process
 is_a: GO:0019751 {is_inferred="true"} ! polyol metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 
 [Term]
 id: GO:1901120 ! tobramycin catabolic process
@@ -68671,7 +69564,7 @@
 
 [Term]
 id: GO:1901149 ! salicylic acid binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
+is_a: GO:0033293 {is_inferred="true"} ! monocarboxylic acid binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 
 [Term]
@@ -69124,6 +70017,7 @@
 
 [Term]
 id: GO:1901236 ! 4-(trimethylammonio)butanoate transmembrane transporter activity
+is_a: GO:0008519 {is_inferred="true"} ! ammonium transmembrane transporter activity
 is_a: GO:0015651 {is_inferred="true"} ! quaternary ammonium group transmembrane transporter activity
 
 [Term]
@@ -69137,20 +70031,23 @@
 
 [Term]
 id: GO:1901239 ! malonate(1-) transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0005310 {is_inferred="true"} ! dicarboxylic acid transmembrane transporter activity
 
 [Term]
 id: GO:1901241 ! 4-hydroxyphenylacetate transmembrane transporter activity
-is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
+is_a: GO:0008028 {is_inferred="true"} ! monocarboxylic acid transmembrane transporter activity
+is_a: GO:1901618 {is_inferred="true"} ! organic hydroxy compound transmembrane transporter activity
 
 [Term]
 id: GO:1901242 ! ATPase-coupled doxorubicin transmembrane transporter activity
-is_a: GO:0042626 {is_inferred="true"} ! ATPase activity, coupled to transmembrane movement of substances
+is_a: GO:0008519 {is_inferred="true"} ! ammonium transmembrane transporter activity
+is_a: GO:0015101 {is_inferred="true"} ! organic cation transmembrane transporter activity
+is_a: GO:0019829 {is_inferred="true"} ! cation-transporting ATPase activity
 is_a: GO:1901505 {is_inferred="true"} ! carbohydrate derivative transporter activity
 
 [Term]
 id: GO:1901243 ! ATPase-coupled methionine transmembrane transporter activity
-is_a: GO:0042626 {is_inferred="true"} ! ATPase activity, coupled to transmembrane movement of substances
+is_a: GO:0019829 {is_inferred="true"} ! cation-transporting ATPase activity
 is_a: GO:0043865 {is_inferred="true"} ! methionine transmembrane transporter activity
 
 [Term]
@@ -69273,6 +70170,7 @@
 
 [Term]
 id: GO:1901266 ! cephalosporin C metabolic process
+is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 is_a: GO:0043645 {is_inferred="true"} ! cephalosporin metabolic process
 
 [Term]
@@ -69279,11 +70177,13 @@
 id: GO:1901267 ! cephalosporin C catabolic process
 is_a: GO:0030655 {is_inferred="true"} ! beta-lactam antibiotic catabolic process
 is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
+is_a: GO:0046395 {is_inferred="true"} ! carboxylic acid catabolic process
 is_a: GO:1901266 {is_inferred="true"} ! cephalosporin C metabolic process
 
 [Term]
 id: GO:1901268 ! cephalosporin C biosynthetic process
 is_a: GO:0043646 {is_inferred="true"} ! cephalosporin biosynthetic process
+is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 is_a: GO:1901266 {is_inferred="true"} ! cephalosporin C metabolic process
 
 [Term]
@@ -69303,17 +70203,17 @@
 [Term]
 id: GO:1901272 ! 2-dehydro-3-deoxy-D-gluconic acid metabolic process
 is_a: GO:0005996 {is_inferred="true"} ! monosaccharide metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0019520 {is_inferred="true"} ! aldonic acid metabolic process
 
 [Term]
 id: GO:1901273 ! 2-dehydro-3-deoxy-D-gluconic acid catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
+is_a: GO:0046176 {is_inferred="true"} ! aldonic acid catabolic process
 is_a: GO:0046365 {is_inferred="true"} ! monosaccharide catabolic process
 is_a: GO:1901272 {is_inferred="true"} ! 2-dehydro-3-deoxy-D-gluconic acid metabolic process
 
 [Term]
 id: GO:1901274 ! 2-dehydro-3-deoxy-D-gluconic acid biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
+is_a: GO:0046175 {is_inferred="true"} ! aldonic acid biosynthetic process
 is_a: GO:0046364 {is_inferred="true"} ! monosaccharide biosynthetic process
 is_a: GO:1901272 {is_inferred="true"} ! 2-dehydro-3-deoxy-D-gluconic acid metabolic process
 
@@ -69342,30 +70242,31 @@
 
 [Term]
 id: GO:1901281 ! fructoselysine catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
+is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
 is_a: GO:0030392 {is_inferred="true"} ! fructosamine catabolic process
 is_a: GO:0030393 {is_inferred="true"} ! fructoselysine metabolic process
-is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
 
 [Term]
 id: GO:1901282 ! fructoselysine biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
+is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 is_a: GO:0030391 {is_inferred="true"} ! fructosamine biosynthetic process
 is_a: GO:0030393 {is_inferred="true"} ! fructoselysine metabolic process
-is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
 
 [Term]
 id: GO:1901283 ! 5,6,7,8-tetrahydromethanopterin metabolic process
+is_a: GO:0043648 {is_inferred="true"} ! dicarboxylic acid metabolic process
 is_a: GO:2001117 {is_inferred="true"} ! tetrahydromethanopterin metabolic process
 
 [Term]
 id: GO:1901284 ! 5,6,7,8-tetrahydromethanopterin catabolic process
 is_a: GO:0042560 {is_inferred="true"} ! pteridine-containing compound catabolic process
+is_a: GO:0043649 {is_inferred="true"} ! dicarboxylic acid catabolic process
 is_a: GO:0046434 {is_inferred="true"} ! organophosphate catabolic process
 is_a: GO:1901283 {is_inferred="true"} ! 5,6,7,8-tetrahydromethanopterin metabolic process
 
 [Term]
 id: GO:1901285 ! 5,6,7,8-tetrahydromethanopterin biosynthetic process
+is_a: GO:0043650 {is_inferred="true"} ! dicarboxylic acid biosynthetic process
 is_a: GO:1901283 {is_inferred="true"} ! 5,6,7,8-tetrahydromethanopterin metabolic process
 is_a: GO:2001118 {is_inferred="true"} ! tetrahydromethanopterin biosynthetic process
 
@@ -69545,6 +70446,7 @@
 [Term]
 id: GO:1901323 ! response to erythromycin
 is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
+is_a: GO:0060359 {is_inferred="true"} ! response to ammonium ion
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
 [Term]
@@ -69676,8 +70578,10 @@
 
 [Term]
 id: GO:1901349 ! glucosinolate transport
-is_a: GO:0006820 {is_inferred="true"} ! anion transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
+is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 is_a: GO:0072348 {is_inferred="true"} ! sulfur compound transport
+is_a: GO:1901264 {is_inferred="true"} ! carbohydrate derivative transport
 
 [Term]
 id: GO:1901350 ! cell-cell signaling involved in cell-cell junction organization
@@ -69774,6 +70678,7 @@
 [Term]
 id: GO:1901369 ! cyclic 2,3-bisphospho-D-glycerate biosynthetic process
 is_a: GO:0006796 {is_inferred="true"} ! phosphate-containing compound metabolic process
+is_a: GO:0046175 {is_inferred="true"} ! aldonic acid biosynthetic process
 is_a: GO:0090407 {is_inferred="true"} ! organophosphate biosynthetic process
 is_a: GO:1901137 {is_inferred="true"} ! carbohydrate derivative biosynthetic process
 
@@ -70008,11 +70913,13 @@
 id: GO:1901413 ! regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA
 is_a: GO:0006521 {is_inferred="true"} ! regulation of cellular amino acid metabolic process
 is_a: GO:0042762 {is_inferred="true"} ! regulation of sulfur metabolic process
+is_a: GO:0051174 {is_inferred="true"} ! regulation of phosphorus metabolic process
 is_a: GO:0051196 {is_inferred="true"} ! regulation of coenzyme metabolic process
 is_a: GO:1901463 {is_inferred="true"} ! regulation of tetrapyrrole biosynthetic process
 
 [Term]
 id: GO:1901414 ! negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA
+is_a: GO:0010563 {is_inferred="true"} ! negative regulation of phosphorus metabolic process
 is_a: GO:0045763 {is_inferred="true"} ! negative regulation of cellular amino acid metabolic process
 is_a: GO:0051175 {is_inferred="true"} ! negative regulation of sulfur metabolic process
 is_a: GO:0051198 {is_inferred="true"} ! negative regulation of coenzyme metabolic process
@@ -70021,6 +70928,7 @@
 
 [Term]
 id: GO:1901415 ! positive regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA
+is_a: GO:0010562 {is_inferred="true"} ! positive regulation of phosphorus metabolic process
 is_a: GO:0045764 {is_inferred="true"} ! positive regulation of cellular amino acid metabolic process
 is_a: GO:0051176 {is_inferred="true"} ! positive regulation of sulfur metabolic process
 is_a: GO:0051197 {is_inferred="true"} ! positive regulation of coenzyme metabolic process
@@ -70307,7 +71215,7 @@
 [Term]
 id: GO:1901475 ! pyruvate transmembrane transport
 is_a: GO:0006848 {is_inferred="true"} ! pyruvate transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
 id: GO:1901476 ! carbohydrate transporter activity
@@ -70329,7 +71237,7 @@
 
 [Term]
 id: GO:1901480 ! oleate transporter activity
-is_a: GO:0005319 {is_inferred="true"} ! lipid transporter activity
+is_a: GO:0005324 {is_inferred="true"} ! long-chain fatty acid transporter activity
 
 [Term]
 id: GO:1901481 ! L-glutamate import involved in cellular response to nitrogen starvation
@@ -70388,19 +71296,16 @@
 
 [Term]
 id: GO:1901494 ! regulation of cysteine metabolic process
-is_a: GO:0031323 {is_inferred="true"} ! regulation of cellular metabolic process
-is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
+is_a: GO:0031335 {is_inferred="true"} ! regulation of sulfur amino acid metabolic process
 
 [Term]
 id: GO:1901495 ! negative regulation of cysteine metabolic process
-is_a: GO:0031324 {is_inferred="true"} ! negative regulation of cellular metabolic process
-is_a: GO:0051172 {is_inferred="true"} ! negative regulation of nitrogen compound metabolic process
+is_a: GO:0031336 {is_inferred="true"} ! negative regulation of sulfur amino acid metabolic process
 is_a: GO:1901494 {is_inferred="true"} ! regulation of cysteine metabolic process
 
 [Term]
 id: GO:1901496 ! positive regulation of cysteine metabolic process
-is_a: GO:0031325 {is_inferred="true"} ! positive regulation of cellular metabolic process
-is_a: GO:0051173 {is_inferred="true"} ! positive regulation of nitrogen compound metabolic process
+is_a: GO:0031337 {is_inferred="true"} ! positive regulation of sulfur amino acid metabolic process
 is_a: GO:1901494 {is_inferred="true"} ! regulation of cysteine metabolic process
 
 [Term]
@@ -70533,6 +71438,8 @@
 
 [Term]
 id: GO:1901523 ! icosanoid catabolic process
+is_a: GO:0006690 {is_inferred="true"} ! icosanoid metabolic process
+is_a: GO:0046395 {is_inferred="true"} ! carboxylic acid catabolic process
 is_a: GO:1901569 {is_inferred="true"} ! fatty acid derivative catabolic process
 
 [Term]
@@ -70568,8 +71475,9 @@
 
 [Term]
 id: GO:1901530 ! response to hypochlorite
+is_a: GO:0000302 {is_inferred="true"} ! response to reactive oxygen species
+is_a: GO:0001101 {is_inferred="true"} ! response to acid chemical
 is_a: GO:0010035 {is_inferred="true"} ! response to inorganic substance
-is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
 [Term]
 id: GO:1901531 ! hypochlorite binding
@@ -70674,8 +71582,8 @@
 
 [Term]
 id: GO:1901549 ! malonic acid uptake transmembrane transporter activity
-is_a: GO:0005310 {is_inferred="true"} ! dicarboxylic acid transmembrane transporter activity
 is_a: GO:0015563 {is_inferred="true"} ! uptake transmembrane transporter activity
+is_a: GO:1901239 {is_inferred="true"} ! malonate(1-) transmembrane transporter activity
 
 [Term]
 id: GO:1901550 ! regulation of endothelial cell development
@@ -70934,7 +71842,7 @@
 [Term]
 id: GO:1901602 ! dethiobiotin binding
 is_a: GO:0033218 {is_inferred="true"} ! amide binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
+is_a: GO:0033293 {is_inferred="true"} ! monocarboxylic acid binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
 
@@ -70953,19 +71861,16 @@
 
 [Term]
 id: GO:1901605 ! alpha-amino acid metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
-is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
+is_a: GO:0006520 {is_inferred="true"} ! cellular amino acid metabolic process
 
 [Term]
 id: GO:1901606 ! alpha-amino acid catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
-is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
+is_a: GO:0009063 {is_inferred="true"} ! cellular amino acid catabolic process
 is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
 
 [Term]
 id: GO:1901607 ! alpha-amino acid biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
-is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
+is_a: GO:0008652 {is_inferred="true"} ! cellular amino acid biosynthetic process
 is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
 
 [Term]
@@ -71346,16 +72251,16 @@
 [Term]
 id: GO:1901688 ! pantothenate import
 is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
+is_a: GO:0042886 {is_inferred="true"} ! amide transport
+is_a: GO:0072337 {is_inferred="true"} ! modified amino acid transport
 
 [Term]
 id: GO:1901689 ! biotin import
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
-is_a: GO:0042886 {is_inferred="true"} ! amide transport
-is_a: GO:0072348 {is_inferred="true"} ! sulfur compound transport
+is_a: GO:0015878 {is_inferred="true"} ! biotin transport
 
 [Term]
 id: GO:1901690 ! dethiobiotin import
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
+is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
 is_a: GO:0042886 {is_inferred="true"} ! amide transport
 
 [Term]
@@ -71379,6 +72284,7 @@
 [Term]
 id: GO:1901695 ! tyramine biosynthetic process
 is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 is_a: GO:1901162 {is_inferred="true"} ! primary amino compound biosynthetic process
 
 [Term]
@@ -71387,10 +72293,10 @@
 
 [Term]
 id: GO:1901697 ! olivetolic acid biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0030639 {is_inferred="true"} ! polyketide biosynthetic process
 is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
+is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 
 [Term]
 id: GO:1901698 ! response to nitrogen compound
@@ -71420,7 +72326,7 @@
 
 [Term]
 id: GO:1901704 ! L-glutamine biosynthetic process
-is_a: GO:0009084 {is_inferred="true"} ! glutamine family amino acid biosynthetic process
+is_a: GO:0006542 {is_inferred="true"} ! glutamine biosynthetic process
 
 [Term]
 id: GO:1901705 ! L-isoleucine biosynthetic process
@@ -71433,8 +72339,7 @@
 
 [Term]
 id: GO:1901707 ! leptomycin B binding
-is_a: GO:0008289 {is_inferred="true"} ! lipid binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
+is_a: GO:0005504 {is_inferred="true"} ! fatty acid binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
 
@@ -71544,23 +72449,23 @@
 [Term]
 id: GO:1901728 ! monensin A metabolic process
 is_a: GO:0006066 {is_inferred="true"} ! alcohol metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
 is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
 
 [Term]
 id: GO:1901729 ! monensin A catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
 is_a: GO:0046164 {is_inferred="true"} ! alcohol catabolic process
 is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
+is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
 is_a: GO:1901728 {is_inferred="true"} ! monensin A metabolic process
 
 [Term]
 id: GO:1901730 ! monensin A biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
 is_a: GO:0046165 {is_inferred="true"} ! alcohol biosynthetic process
+is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
 is_a: GO:1901728 {is_inferred="true"} ! monensin A metabolic process
 
@@ -71590,18 +72495,18 @@
 
 [Term]
 id: GO:1901735 ! (R)-mevalonic acid metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
 
 [Term]
 id: GO:1901736 ! (R)-mevalonic acid catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
+is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 is_a: GO:1901616 {is_inferred="true"} ! organic hydroxy compound catabolic process
 is_a: GO:1901735 {is_inferred="true"} ! (R)-mevalonic acid metabolic process
 
 [Term]
 id: GO:1901737 ! (R)-mevalonic acid biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
+is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 is_a: GO:1901617 {is_inferred="true"} ! organic hydroxy compound biosynthetic process
 is_a: GO:1901735 {is_inferred="true"} ! (R)-mevalonic acid metabolic process
 
@@ -71630,6 +72535,7 @@
 [Term]
 id: GO:1901742 ! 2-deoxystreptamine metabolic process
 is_a: GO:0019751 {is_inferred="true"} ! polyol metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 
 [Term]
 id: GO:1901743 ! 2-deoxystreptamine catabolic process
@@ -71657,47 +72563,45 @@
 
 [Term]
 id: GO:1901748 ! leukotriene D4 metabolic process
+is_a: GO:0006691 {is_inferred="true"} ! leukotriene metabolic process
 is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
-is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
-is_a: GO:1901568 {is_inferred="true"} ! fatty acid derivative metabolic process
 
 [Term]
 id: GO:1901749 ! leukotriene D4 catabolic process
+is_a: GO:0036100 {is_inferred="true"} ! leukotriene catabolic process
 is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
-is_a: GO:1901523 {is_inferred="true"} ! icosanoid catabolic process
 is_a: GO:1901748 {is_inferred="true"} ! leukotriene D4 metabolic process
 
 [Term]
 id: GO:1901750 ! leukotriene D4 biosynthetic process
+is_a: GO:0019370 {is_inferred="true"} ! leukotriene biosynthetic process
 is_a: GO:0044272 {is_inferred="true"} ! sulfur compound biosynthetic process
-is_a: GO:1901570 {is_inferred="true"} ! fatty acid derivative biosynthetic process
 is_a: GO:1901748 {is_inferred="true"} ! leukotriene D4 metabolic process
 
 [Term]
 id: GO:1901751 ! leukotriene A4 metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
-is_a: GO:0006629 {is_inferred="true"} ! lipid metabolic process
+is_a: GO:0001676 {is_inferred="true"} ! long-chain fatty acid metabolic process
+is_a: GO:0006691 {is_inferred="true"} ! leukotriene metabolic process
+is_a: GO:0031407 {is_inferred="true"} ! oxylipin metabolic process
 is_a: GO:0097176 {is_inferred="true"} ! epoxide metabolic process
-is_a: GO:1901568 {is_inferred="true"} ! fatty acid derivative metabolic process
 
 [Term]
 id: GO:1901752 ! leukotriene A4 catabolic process
-is_a: GO:0016042 {is_inferred="true"} ! lipid catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
+is_a: GO:0036100 {is_inferred="true"} ! leukotriene catabolic process
+is_a: GO:0042758 {is_inferred="true"} ! long-chain fatty acid catabolic process
 is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
 is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
 is_a: GO:1901502 {is_inferred="true"} ! ether catabolic process
-is_a: GO:1901523 {is_inferred="true"} ! icosanoid catabolic process
 is_a: GO:1901751 {is_inferred="true"} ! leukotriene A4 metabolic process
 
 [Term]
 id: GO:1901753 ! leukotriene A4 biosynthetic process
-is_a: GO:0008610 {is_inferred="true"} ! lipid biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
+is_a: GO:0019370 {is_inferred="true"} ! leukotriene biosynthetic process
+is_a: GO:0031408 {is_inferred="true"} ! oxylipin biosynthetic process
+is_a: GO:0042759 {is_inferred="true"} ! long-chain fatty acid biosynthetic process
 is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
 is_a: GO:1901503 {is_inferred="true"} ! ether biosynthetic process
-is_a: GO:1901570 {is_inferred="true"} ! fatty acid derivative biosynthetic process
 is_a: GO:1901751 {is_inferred="true"} ! leukotriene A4 metabolic process
 
 [Term]
@@ -71759,15 +72663,16 @@
 [Term]
 id: GO:1901764 ! phosphinothricin metabolic process
 is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
+is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
 
 [Term]
 id: GO:1901765 ! phosphinothricin catabolic process
-is_a: GO:0009056 {is_inferred="true"} ! catabolic process
+is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
 is_a: GO:1901764 {is_inferred="true"} ! phosphinothricin metabolic process
 
 [Term]
 id: GO:1901766 ! phosphinothricin biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
 is_a: GO:1901764 {is_inferred="true"} ! phosphinothricin metabolic process
 
 [Term]
@@ -71850,15 +72755,15 @@
 
 [Term]
 id: GO:1901778 ! pentalenolactone metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
 is_a: GO:0006714 {is_inferred="true"} ! sesquiterpenoid metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 is_a: GO:0097176 {is_inferred="true"} ! epoxide metabolic process
 is_a: GO:1901334 {is_inferred="true"} ! lactone metabolic process
 
 [Term]
 id: GO:1901779 ! pentalenolactone catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
 is_a: GO:0016107 {is_inferred="true"} ! sesquiterpenoid catabolic process
+is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 is_a: GO:1901335 {is_inferred="true"} ! lactone catabolic process
 is_a: GO:1901502 {is_inferred="true"} ! ether catabolic process
 is_a: GO:1901778 {is_inferred="true"} ! pentalenolactone metabolic process
@@ -71865,8 +72770,8 @@
 
 [Term]
 id: GO:1901780 ! pentalenolactone biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0016106 {is_inferred="true"} ! sesquiterpenoid biosynthetic process
+is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 is_a: GO:1901336 {is_inferred="true"} ! lactone biosynthetic process
 is_a: GO:1901503 {is_inferred="true"} ! ether biosynthetic process
 is_a: GO:1901778 {is_inferred="true"} ! pentalenolactone metabolic process
@@ -71874,15 +72779,20 @@
 [Term]
 id: GO:1901781 ! p-cumate metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0042537 {is_inferred="true"} ! benzene-containing compound metabolic process
 
 [Term]
 id: GO:1901782 ! p-cumate catabolic process
+is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
+is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
 is_a: GO:1901781 {is_inferred="true"} ! p-cumate metabolic process
 
 [Term]
 id: GO:1901783 ! p-cumate biosynthetic process
+is_a: GO:0019438 {is_inferred="true"} ! aromatic compound biosynthetic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
+is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
 is_a: GO:1901781 {is_inferred="true"} ! p-cumate metabolic process
 
 [Term]
@@ -72195,16 +73105,25 @@
 
 [Term]
 id: GO:1901847 ! nicotinate metabolic process
+is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
+is_a: GO:0009820 {is_inferred="true"} ! alkaloid metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0072524 {is_inferred="true"} ! pyridine-containing compound metabolic process
 
 [Term]
 id: GO:1901848 ! nicotinate catabolic process
+is_a: GO:0009822 {is_inferred="true"} ! alkaloid catabolic process
+is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
+is_a: GO:0072526 {is_inferred="true"} ! pyridine-containing compound catabolic process
 is_a: GO:1901847 {is_inferred="true"} ! nicotinate metabolic process
 
 [Term]
 id: GO:1901849 ! nicotinate biosynthetic process
+is_a: GO:0009821 {is_inferred="true"} ! alkaloid biosynthetic process
+is_a: GO:0019438 {is_inferred="true"} ! aromatic compound biosynthetic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
+is_a: GO:0072525 {is_inferred="true"} ! pyridine-containing compound biosynthetic process
 is_a: GO:1901847 {is_inferred="true"} ! nicotinate metabolic process
 
 [Term]
@@ -72229,6 +73148,7 @@
 
 [Term]
 id: GO:1901853 ! 5,6,7,8-tetrahydrosarcinapterin metabolic process
+is_a: GO:0072350 {is_inferred="true"} ! tricarboxylic acid metabolic process
 is_a: GO:2001117 {is_inferred="true"} ! tetrahydromethanopterin metabolic process
 
 [Term]
@@ -72235,10 +73155,12 @@
 id: GO:1901854 ! 5,6,7,8-tetrahydrosarcinapterin catabolic process
 is_a: GO:0042560 {is_inferred="true"} ! pteridine-containing compound catabolic process
 is_a: GO:0046434 {is_inferred="true"} ! organophosphate catabolic process
+is_a: GO:0072352 {is_inferred="true"} ! tricarboxylic acid catabolic process
 is_a: GO:1901853 {is_inferred="true"} ! 5,6,7,8-tetrahydrosarcinapterin metabolic process
 
 [Term]
 id: GO:1901855 ! 5,6,7,8-tetrahydrosarcinapterin biosynthetic process
+is_a: GO:0072351 {is_inferred="true"} ! tricarboxylic acid biosynthetic process
 is_a: GO:1901853 {is_inferred="true"} ! 5,6,7,8-tetrahydrosarcinapterin metabolic process
 is_a: GO:2001118 {is_inferred="true"} ! tetrahydromethanopterin biosynthetic process
 
@@ -72300,6 +73222,7 @@
 [Term]
 id: GO:1901867 ! ecgonine methyl ester metabolic process
 is_a: GO:0046448 {is_inferred="true"} ! tropane alkaloid metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 
 [Term]
 id: GO:1901868 ! ecgonine methyl ester catabolic process
@@ -72317,6 +73240,7 @@
 id: GO:1901870 ! ecgonone methyl ester metabolic process
 is_a: GO:0042180 {is_inferred="true"} ! cellular ketone metabolic process
 is_a: GO:0046448 {is_inferred="true"} ! tropane alkaloid metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 
 [Term]
 id: GO:1901871 ! ecgonone methyl ester catabolic process
@@ -72836,7 +73760,8 @@
 
 [Term]
 id: GO:1901973 ! proline binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
+is_a: GO:0016597 {is_inferred="true"} ! amino acid binding
+is_a: GO:0043169 {is_inferred="true"} ! cation binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
 
@@ -72846,8 +73771,9 @@
 
 [Term]
 id: GO:1901975 ! glycerate transmembrane transport
+is_a: GO:0034219 {is_inferred="true"} ! carbohydrate transmembrane transport
 is_a: GO:0042873 {is_inferred="true"} ! aldonate transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
 id: GO:1901976 ! regulation of cell cycle checkpoint
@@ -72960,7 +73886,7 @@
 [Term]
 id: GO:1901997 ! negative regulation of indoleacetic acid biosynthetic process via tryptophan
 is_a: GO:0032353 {is_inferred="true"} ! negative regulation of hormone biosynthetic process
-is_a: GO:0033239 {is_inferred="true"} ! negative regulation of cellular amine metabolic process
+is_a: GO:0045763 {is_inferred="true"} ! negative regulation of cellular amino acid metabolic process
 is_a: GO:0090356 {is_inferred="true"} ! negative regulation of auxin metabolic process
 is_a: GO:1901996 {is_inferred="true"} ! regulation of indoleacetic acid biosynthetic process via tryptophan
 
@@ -72970,16 +73896,18 @@
 
 [Term]
 id: GO:1901999 ! homogentisate metabolic process
+is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 
 [Term]
 id: GO:1902000 ! homogentisate catabolic process
+is_a: GO:0019336 {is_inferred="true"} ! phenol-containing compound catabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
 is_a: GO:1901999 {is_inferred="true"} ! homogentisate metabolic process
 
 [Term]
 id: GO:1902001 ! fatty acid transmembrane transport
-is_a: GO:0006869 {is_inferred="true"} ! lipid transport
+is_a: GO:0015908 {is_inferred="true"} ! fatty acid transport
 is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
@@ -73075,16 +74003,18 @@
 
 [Term]
 id: GO:1902022 ! L-lysine transport
-is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
+is_a: GO:0015807 {is_inferred="true"} ! L-amino acid transport
+is_a: GO:0015819 {is_inferred="true"} ! lysine transport
 
 [Term]
 id: GO:1902023 ! L-arginine transport
-is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
+is_a: GO:0015807 {is_inferred="true"} ! L-amino acid transport
+is_a: GO:0015809 {is_inferred="true"} ! arginine transport
 
 [Term]
 id: GO:1902024 ! L-histidine transport
-is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
-is_a: GO:0045117 {is_inferred="true"} ! azole transport
+is_a: GO:0015807 {is_inferred="true"} ! L-amino acid transport
+is_a: GO:0015817 {is_inferred="true"} ! histidine transport
 
 [Term]
 id: GO:1902025 ! nitrate import
@@ -73223,11 +74153,13 @@
 
 [Term]
 id: GO:1902051 ! (25S)-Delta(4)-dafachronate binding
-is_a: GO:0031406 {is_inferred="true"} ! carboxylic acid binding
+is_a: GO:0033293 {is_inferred="true"} ! monocarboxylic acid binding
+is_a: GO:1990239 {is_inferred="true"} ! steroid hormone binding
 
 [Term]
 id: GO:1902052 ! (25S)-Delta(7)-dafachronate binding
-is_a: GO:0031406 {is_inferred="true"} ! carboxylic acid binding
+is_a: GO:0033293 {is_inferred="true"} ! monocarboxylic acid binding
+is_a: GO:1990239 {is_inferred="true"} ! steroid hormone binding
 
 [Term]
 id: GO:1902053 ! regulation of neosartoricin biosynthetic process
@@ -73248,11 +74180,15 @@
 
 [Term]
 id: GO:1902056 ! (25S)-Delta(7)-dafachronate metabolic process
-is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
+is_a: GO:0008202 {is_inferred="true"} ! steroid metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0042180 {is_inferred="true"} ! cellular ketone metabolic process
 
 [Term]
 id: GO:1902057 ! (25S)-Delta(4)-dafachronate metabolic process
-is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
+is_a: GO:0008202 {is_inferred="true"} ! steroid metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0042180 {is_inferred="true"} ! cellular ketone metabolic process
 
 [Term]
 id: GO:1902058 ! regulation of sporocarp development involved in sexual reproduction
@@ -73292,8 +74228,7 @@
 
 [Term]
 id: GO:1902065 ! response to L-glutamate
-is_a: GO:0010243 {is_inferred="true"} ! response to organonitrogen compound
-is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
+is_a: GO:0043200 {is_inferred="true"} ! response to amino acid
 
 [Term]
 id: GO:1902066 ! regulation of cell wall pectin metabolic process
@@ -73303,7 +74238,7 @@
 
 [Term]
 id: GO:1902067 ! silicic acid import
-is_a: GO:0006810 {is_inferred="true"} ! transport
+is_a: GO:0015708 {is_inferred="true"} ! silicate transport
 
 [Term]
 id: GO:1902068 ! regulation of sphingolipid mediated signaling pathway
@@ -73361,8 +74296,8 @@
 
 [Term]
 id: GO:1902079 ! D-valine catabolic process
-is_a: GO:0009083 {is_inferred="true"} ! branched-chain amino acid catabolic process
-is_a: GO:1901606 {is_inferred="true"} ! alpha-amino acid catabolic process
+is_a: GO:0006574 {is_inferred="true"} ! valine catabolic process
+is_a: GO:0019478 {is_inferred="true"} ! D-amino acid catabolic process
 is_a: GO:1902114 {is_inferred="true"} ! D-valine metabolic process
 
 [Term]
@@ -73389,12 +74324,12 @@
 
 [Term]
 id: GO:1902084 ! fumagillin metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0019752 {is_inferred="true"} ! carboxylic acid metabolic process
 is_a: GO:0097176 {is_inferred="true"} ! epoxide metabolic process
 
 [Term]
 id: GO:1902085 ! fumagillin catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
+is_a: GO:0046395 {is_inferred="true"} ! carboxylic acid catabolic process
 is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
 is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
 is_a: GO:1901502 {is_inferred="true"} ! ether catabolic process
@@ -73402,8 +74337,8 @@
 
 [Term]
 id: GO:1902086 ! fumagillin biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
+is_a: GO:0046394 {is_inferred="true"} ! carboxylic acid biosynthetic process
 is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
 is_a: GO:1901503 {is_inferred="true"} ! ether biosynthetic process
 is_a: GO:1902084 {is_inferred="true"} ! fumagillin metabolic process
@@ -73546,8 +74481,8 @@
 
 [Term]
 id: GO:1902114 ! D-valine metabolic process
-is_a: GO:0009081 {is_inferred="true"} ! branched-chain amino acid metabolic process
-is_a: GO:1901605 {is_inferred="true"} ! alpha-amino acid metabolic process
+is_a: GO:0006573 {is_inferred="true"} ! valine metabolic process
+is_a: GO:0046416 {is_inferred="true"} ! D-amino acid metabolic process
 
 [Term]
 id: GO:1902115 ! regulation of organelle assembly
@@ -73583,13 +74518,11 @@
 
 [Term]
 id: GO:1902121 ! lithocholic acid binding
-is_a: GO:0005496 {is_inferred="true"} ! steroid binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
+is_a: GO:0032052 {is_inferred="true"} ! bile acid binding
 
 [Term]
 id: GO:1902122 ! chenodeoxycholic acid binding
-is_a: GO:0005496 {is_inferred="true"} ! steroid binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
+is_a: GO:0032052 {is_inferred="true"} ! bile acid binding
 
 [Term]
 id: GO:1902123 ! (-)-pinoresinol catabolic process
@@ -73934,62 +74867,58 @@
 
 [Term]
 id: GO:1902189 ! 2-methylbutanoyl-CoA(4-) metabolic process
-is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
+is_a: GO:0035337 {is_inferred="true"} ! fatty-acyl-CoA metabolic process
 
 [Term]
 id: GO:1902190 ! 2-methylbutanoyl-CoA(4-) catabolic process
-is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
+is_a: GO:0036115 {is_inferred="true"} ! fatty-acyl-CoA catabolic process
 is_a: GO:1902189 {is_inferred="true"} ! 2-methylbutanoyl-CoA(4-) metabolic process
 
 [Term]
 id: GO:1902191 ! 2-methylbutanoyl-CoA(4-) biosynthetic process
-is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
+is_a: GO:0046949 {is_inferred="true"} ! fatty-acyl-CoA biosynthetic process
 is_a: GO:1902189 {is_inferred="true"} ! 2-methylbutanoyl-CoA(4-) metabolic process
 
 [Term]
 id: GO:1902192 ! 2-methylbut-2-enoyl-CoA(4-) metabolic process
-is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
+is_a: GO:0035337 {is_inferred="true"} ! fatty-acyl-CoA metabolic process
 
 [Term]
 id: GO:1902193 ! 2-methylbut-2-enoyl-CoA(4-) catabolic process
-is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
+is_a: GO:0036115 {is_inferred="true"} ! fatty-acyl-CoA catabolic process
 is_a: GO:1902192 {is_inferred="true"} ! 2-methylbut-2-enoyl-CoA(4-) metabolic process
 
 [Term]
 id: GO:1902194 ! 2-methylbut-2-enoyl-CoA(4-) biosynthetic process
-is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
+is_a: GO:0046949 {is_inferred="true"} ! fatty-acyl-CoA biosynthetic process
 is_a: GO:1902192 {is_inferred="true"} ! 2-methylbut-2-enoyl-CoA(4-) metabolic process
 
 [Term]
 id: GO:1902195 ! isovaleryl-CoA(4-) metabolic process
-is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
+is_a: GO:0035337 {is_inferred="true"} ! fatty-acyl-CoA metabolic process
 
 [Term]
 id: GO:1902196 ! isovaleryl-CoA(4-) catabolic process
-is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
+is_a: GO:0036115 {is_inferred="true"} ! fatty-acyl-CoA catabolic process
 is_a: GO:1902195 {is_inferred="true"} ! isovaleryl-CoA(4-) metabolic process
 
 [Term]
 id: GO:1902197 ! isovaleryl-CoA(4-) biosynthetic process
-is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
+is_a: GO:0046949 {is_inferred="true"} ! fatty-acyl-CoA biosynthetic process
 is_a: GO:1902195 {is_inferred="true"} ! isovaleryl-CoA(4-) metabolic process
 
 [Term]
 id: GO:1902198 ! 3-methylbut-2-enoyl-CoA(4-) metabolic process
-is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
+is_a: GO:0035337 {is_inferred="true"} ! fatty-acyl-CoA metabolic process
 
 [Term]
 id: GO:1902199 ! 3-methylbut-2-enoyl-CoA(4-) catabolic process
-is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
+is_a: GO:0036115 {is_inferred="true"} ! fatty-acyl-CoA catabolic process
 is_a: GO:1902198 {is_inferred="true"} ! 3-methylbut-2-enoyl-CoA(4-) metabolic process
 
 [Term]
 id: GO:1902200 ! 3-methylbut-2-enoyl-CoA(4-) biosynthetic process
-is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
+is_a: GO:0046949 {is_inferred="true"} ! fatty-acyl-CoA biosynthetic process
 is_a: GO:1902198 {is_inferred="true"} ! 3-methylbut-2-enoyl-CoA(4-) metabolic process
 
 [Term]
@@ -74196,17 +75125,19 @@
 
 [Term]
 id: GO:1902241 ! copal-8-ol diphosphate(3-) metabolic process
-is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
+is_a: GO:0006644 {is_inferred="true"} ! phospholipid metabolic process
+is_a: GO:0016101 {is_inferred="true"} ! diterpenoid metabolic process
 
 [Term]
 id: GO:1902242 ! copal-8-ol diphosphate(3-) catabolic process
-is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
+is_a: GO:0009395 {is_inferred="true"} ! phospholipid catabolic process
+is_a: GO:0016103 {is_inferred="true"} ! diterpenoid catabolic process
 is_a: GO:1902241 {is_inferred="true"} ! copal-8-ol diphosphate(3-) metabolic process
 
 [Term]
 id: GO:1902243 ! copal-8-ol diphosphate(3-) biosynthetic process
-is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
+is_a: GO:0008654 {is_inferred="true"} ! phospholipid biosynthetic process
+is_a: GO:0016102 {is_inferred="true"} ! diterpenoid biosynthetic process
 is_a: GO:1902241 {is_inferred="true"} ! copal-8-ol diphosphate(3-) metabolic process
 
 [Term]
@@ -74234,11 +75165,13 @@
 
 [Term]
 id: GO:1902248 ! 5-O-phosphono-alpha-D-ribofuranosyl diphosphate binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:0097367 {is_inferred="true"} ! carbohydrate derivative binding
 
 [Term]
 id: GO:1902249 ! IMP binding
 is_a: GO:0032555 {is_inferred="true"} ! purine ribonucleotide binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 
 [Term]
 id: GO:1902250 ! regulation of erythrocyte apoptotic process
@@ -74314,6 +75247,7 @@
 [Term]
 id: GO:1902265 ! abscisic acid homeostasis
 is_a: GO:0055081 {is_inferred="true"} ! anion homeostasis
+is_a: GO:0055088 {is_inferred="true"} ! lipid homeostasis
 
 [Term]
 id: GO:1902266 ! cellular abscisic acid homeostasis
@@ -74345,17 +75279,17 @@
 
 [Term]
 id: GO:1902272 ! regulation of (R)-carnitine transmembrane transport
-is_a: GO:0034762 {is_inferred="true"} ! regulation of transmembrane transport
+is_a: GO:1904062 {is_inferred="true"} ! regulation of cation transmembrane transport
 
 [Term]
 id: GO:1902273 ! negative regulation of (R)-carnitine transmembrane transport
-is_a: GO:0034763 {is_inferred="true"} ! negative regulation of transmembrane transport
 is_a: GO:1902272 {is_inferred="true"} ! regulation of (R)-carnitine transmembrane transport
+is_a: GO:1904063 {is_inferred="true"} ! negative regulation of cation transmembrane transport
 
 [Term]
 id: GO:1902274 ! positive regulation of (R)-carnitine transmembrane transport
-is_a: GO:0034764 {is_inferred="true"} ! positive regulation of transmembrane transport
 is_a: GO:1902272 {is_inferred="true"} ! regulation of (R)-carnitine transmembrane transport
+is_a: GO:1904064 {is_inferred="true"} ! positive regulation of cation transmembrane transport
 
 [Term]
 id: GO:1902275 ! regulation of chromatin organization
@@ -74575,25 +75509,21 @@
 
 [Term]
 id: GO:1902321 ! methyl-branched fatty acid biosynthetic process
-is_a: GO:0008610 {is_inferred="true"} ! lipid biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
+is_a: GO:0006633 {is_inferred="true"} ! fatty acid biosynthetic process
 is_a: GO:0097089 {is_inferred="true"} ! methyl-branched fatty acid metabolic process
 
 [Term]
 id: GO:1902322 ! regulation of methyl-branched fatty acid biosynthetic process
-is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
-is_a: GO:0046890 {is_inferred="true"} ! regulation of lipid biosynthetic process
+is_a: GO:0042304 {is_inferred="true"} ! regulation of fatty acid biosynthetic process
 
 [Term]
 id: GO:1902323 ! negative regulation of methyl-branched fatty acid biosynthetic process
-is_a: GO:0031327 {is_inferred="true"} ! negative regulation of cellular biosynthetic process
-is_a: GO:0051055 {is_inferred="true"} ! negative regulation of lipid biosynthetic process
+is_a: GO:0045717 {is_inferred="true"} ! negative regulation of fatty acid biosynthetic process
 is_a: GO:1902322 {is_inferred="true"} ! regulation of methyl-branched fatty acid biosynthetic process
 
 [Term]
 id: GO:1902324 ! positive regulation of methyl-branched fatty acid biosynthetic process
-is_a: GO:0031328 {is_inferred="true"} ! positive regulation of cellular biosynthetic process
-is_a: GO:0046889 {is_inferred="true"} ! positive regulation of lipid biosynthetic process
+is_a: GO:0045723 {is_inferred="true"} ! positive regulation of fatty acid biosynthetic process
 is_a: GO:1902322 {is_inferred="true"} ! regulation of methyl-branched fatty acid biosynthetic process
 
 [Term]
@@ -74745,12 +75675,12 @@
 [Term]
 id: GO:1902356 ! oxaloacetate(2-) transmembrane transport
 is_a: GO:0015729 {is_inferred="true"} ! oxaloacetate transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
 id: GO:1902357 ! 2-isopropylmalate(2-) transmembrane transport
 is_a: GO:0034659 {is_inferred="true"} ! isopropylmalate transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
 id: GO:1902358 ! sulfate transmembrane transport
@@ -74877,16 +75807,25 @@
 
 [Term]
 id: GO:1902384 ! glycyrrhetinate metabolic process
+is_a: GO:0019742 {is_inferred="true"} ! pentacyclic triterpenoid metabolic process
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
+is_a: GO:0042180 {is_inferred="true"} ! cellular ketone metabolic process
+is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
 
 [Term]
 id: GO:1902385 ! glycyrrhetinate catabolic process
+is_a: GO:0019741 {is_inferred="true"} ! pentacyclic triterpenoid catabolic process
+is_a: GO:0042182 {is_inferred="true"} ! ketone catabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
+is_a: GO:1901616 {is_inferred="true"} ! organic hydroxy compound catabolic process
 is_a: GO:1902384 {is_inferred="true"} ! glycyrrhetinate metabolic process
 
 [Term]
 id: GO:1902386 ! glycyrrhetinate biosynthetic process
+is_a: GO:0019745 {is_inferred="true"} ! pentacyclic triterpenoid biosynthetic process
+is_a: GO:0042181 {is_inferred="true"} ! ketone biosynthetic process
 is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
+is_a: GO:1901617 {is_inferred="true"} ! organic hydroxy compound biosynthetic process
 is_a: GO:1902384 {is_inferred="true"} ! glycyrrhetinate metabolic process
 
 [Term]
@@ -75156,6 +76095,7 @@
 
 [Term]
 id: GO:1902444 ! riboflavin binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
 
@@ -75273,6 +76213,7 @@
 [Term]
 id: GO:1902475 ! L-alpha-amino acid transmembrane transport
 is_a: GO:0003333 {is_inferred="true"} ! amino acid transmembrane transport
+is_a: GO:0015807 {is_inferred="true"} ! L-amino acid transport
 
 [Term]
 id: GO:1902476 ! chloride transmembrane transport
@@ -75318,7 +76259,8 @@
 
 [Term]
 id: GO:1902485 ! L-cysteine binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
+is_a: GO:0016597 {is_inferred="true"} ! amino acid binding
+is_a: GO:0043169 {is_inferred="true"} ! cation binding
 is_a: GO:1901681 {is_inferred="true"} ! sulfur compound binding
 
 [Term]
@@ -75465,6 +76407,7 @@
 
 [Term]
 id: GO:1902516 ! sn-glycerol 3-phosphate binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:0097367 {is_inferred="true"} ! carbohydrate derivative binding
 
 [Term]
@@ -75482,6 +76425,7 @@
 [Term]
 id: GO:1902520 ! response to doxorubicin
 is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
+is_a: GO:0060359 {is_inferred="true"} ! response to ammonium ion
 is_a: GO:1901654 {is_inferred="true"} ! response to ketone
 is_a: GO:1903416 {is_inferred="true"} ! response to glycoside
 
@@ -75492,6 +76436,7 @@
 
 [Term]
 id: GO:1902522 ! response to 4'-epidoxorubicin
+is_a: GO:0060359 {is_inferred="true"} ! response to ammonium ion
 is_a: GO:1901654 {is_inferred="true"} ! response to ketone
 is_a: GO:1903416 {is_inferred="true"} ! response to glycoside
 
@@ -75652,15 +76597,18 @@
 id: GO:1902557 ! 5'-adenylyl sulfate transmembrane transporter activity
 is_a: GO:0000295 {is_inferred="true"} ! adenine nucleotide transmembrane transporter activity
 is_a: GO:0005346 {is_inferred="true"} ! purine ribonucleotide transmembrane transporter activity
+is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 is_a: GO:0015211 {is_inferred="true"} ! purine nucleoside transmembrane transporter activity
 is_a: GO:1901682 {is_inferred="true"} ! sulfur compound transmembrane transporter activity
 
 [Term]
 id: GO:1902558 ! 5'-adenylyl sulfate transmembrane transport
+is_a: GO:0015711 {is_inferred="true"} ! organic anion transport
 is_a: GO:0015860 {is_inferred="true"} ! purine nucleoside transmembrane transport
 is_a: GO:0015868 {is_inferred="true"} ! purine ribonucleotide transport
 is_a: GO:0051503 {is_inferred="true"} ! adenine nucleotide transport
 is_a: GO:0072348 {is_inferred="true"} ! sulfur compound transport
+is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 is_a: GO:1901679 {is_inferred="true"} ! nucleotide transmembrane transport
 
 [Term]
@@ -75667,6 +76615,7 @@
 id: GO:1902559 ! 3'-phospho-5'-adenylyl sulfate transmembrane transport
 is_a: GO:0015860 {is_inferred="true"} ! purine nucleoside transmembrane transport
 is_a: GO:0046963 {is_inferred="true"} ! 3'-phosphoadenosine 5'-phosphosulfate transport
+is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 is_a: GO:1901679 {is_inferred="true"} ! nucleotide transmembrane transport
 
 [Term]
@@ -75858,8 +76807,8 @@
 
 [Term]
 id: GO:1902598 ! creatine transmembrane transport
+is_a: GO:0003333 {is_inferred="true"} ! amino acid transmembrane transport
 is_a: GO:0015881 {is_inferred="true"} ! creatine transport
-is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
 
 [Term]
 id: GO:1902599 ! sulfathiazole transmembrane transport
@@ -75882,12 +76831,13 @@
 [Term]
 id: GO:1902603 ! carnitine transmembrane transport
 is_a: GO:0015879 {is_inferred="true"} ! carnitine transport
-is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
+is_a: GO:0072488 {is_inferred="true"} ! ammonium transmembrane transport
 
 [Term]
 id: GO:1902604 ! p-aminobenzoyl-glutamate transmembrane transport
 is_a: GO:0015814 {is_inferred="true"} ! p-aminobenzoyl-glutamate transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:0035442 {is_inferred="true"} ! dipeptide transmembrane transport
+is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
 id: GO:1902605 ! heterotrimeric G-protein complex assembly
@@ -75912,8 +76862,8 @@
 
 [Term]
 id: GO:1902609 ! (R)-2-hydroxy-alpha-linolenic acid biosynthetic process
-is_a: GO:0008610 {is_inferred="true"} ! lipid biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
+is_a: GO:0006636 {is_inferred="true"} ! unsaturated fatty acid biosynthetic process
+is_a: GO:0042759 {is_inferred="true"} ! long-chain fatty acid biosynthetic process
 is_a: GO:1901617 {is_inferred="true"} ! organic hydroxy compound biosynthetic process
 
 [Term]
@@ -75950,11 +76900,12 @@
 
 [Term]
 id: GO:1902617 ! response to fluoride
+is_a: GO:0001101 {is_inferred="true"} ! response to acid chemical
 is_a: GO:0010035 {is_inferred="true"} ! response to inorganic substance
 
 [Term]
 id: GO:1902618 ! cellular response to fluoride
-is_a: GO:0070887 {is_inferred="true"} ! cellular response to chemical stimulus
+is_a: GO:0071229 {is_inferred="true"} ! cellular response to acid chemical
 is_a: GO:1902617 {is_inferred="true"} ! response to fluoride
 
 [Term]
@@ -76330,13 +77281,12 @@
 
 [Term]
 id: GO:1902696 ! glycine catabolic process to isobutanol
-is_a: GO:0009071 {is_inferred="true"} ! serine family amino acid catabolic process
+is_a: GO:0006546 {is_inferred="true"} ! glycine catabolic process
 is_a: GO:1901960 {is_inferred="true"} ! isobutanol metabolic process
 
 [Term]
 id: GO:1902697 ! valine catabolic process to isobutanol
-is_a: GO:0009083 {is_inferred="true"} ! branched-chain amino acid catabolic process
-is_a: GO:1901606 {is_inferred="true"} ! alpha-amino acid catabolic process
+is_a: GO:0006574 {is_inferred="true"} ! valine catabolic process
 is_a: GO:1901960 {is_inferred="true"} ! isobutanol metabolic process
 
 [Term]
@@ -76688,11 +77638,13 @@
 
 [Term]
 id: GO:1902776 ! 6-sulfoquinovose(1-) metabolic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
+is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
+is_a: GO:1901135 {is_inferred="true"} ! carbohydrate derivative metabolic process
 
 [Term]
 id: GO:1902777 ! 6-sulfoquinovose(1-) catabolic process
-is_a: GO:1901575 {is_inferred="true"} ! organic substance catabolic process
+is_a: GO:0044273 {is_inferred="true"} ! sulfur compound catabolic process
+is_a: GO:1901136 {is_inferred="true"} ! carbohydrate derivative catabolic process
 is_a: GO:1902776 {is_inferred="true"} ! 6-sulfoquinovose(1-) metabolic process
 
 [Term]
@@ -76921,6 +77873,7 @@
 
 [Term]
 id: GO:1902825 ! proline import into cell
+is_a: GO:0015824 {is_inferred="true"} ! proline transport
 is_a: GO:1902837 {is_inferred="true"} ! amino acid import into cell
 
 [Term]
@@ -76964,6 +77917,7 @@
 [Term]
 id: GO:1902834 ! regulation of proline import into cell
 is_a: GO:0010958 {is_inferred="true"} ! regulation of amino acid import
+is_a: GO:0070881 {is_inferred="true"} ! regulation of proline transport
 
 [Term]
 id: GO:1902835 ! negative regulation of proline import into cell
@@ -77420,8 +78374,7 @@
 
 [Term]
 id: GO:1902925 ! poly(hydroxyalkanoate) biosynthetic process from fatty acid
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
-is_a: GO:0006629 {is_inferred="true"} ! lipid metabolic process
+is_a: GO:0006631 {is_inferred="true"} ! fatty acid metabolic process
 is_a: GO:0044711 {is_inferred="true"} ! single-organism biosynthetic process
 is_a: GO:1901441 {is_inferred="true"} ! poly(hydroxyalkanoate) biosynthetic process
 
@@ -78235,6 +79188,7 @@
 id: GO:1903091 ! pyridoxamine transmembrane transport
 is_a: GO:0031922 {is_inferred="true"} ! pyridoxamine transport
 is_a: GO:0035461 {is_inferred="true"} ! vitamin transmembrane transport
+is_a: GO:0072488 {is_inferred="true"} ! ammonium transmembrane transport
 
 [Term]
 id: GO:1903092 ! pyridoxine transmembrane transport
@@ -78670,20 +79624,17 @@
 
 [Term]
 id: GO:1903195 ! regulation of L-dopa biosynthetic process
-is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
-is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
+is_a: GO:2000282 {is_inferred="true"} ! regulation of cellular amino acid biosynthetic process
 
 [Term]
 id: GO:1903196 ! negative regulation of L-dopa biosynthetic process
-is_a: GO:0031327 {is_inferred="true"} ! negative regulation of cellular biosynthetic process
-is_a: GO:0051172 {is_inferred="true"} ! negative regulation of nitrogen compound metabolic process
 is_a: GO:1903195 {is_inferred="true"} ! regulation of L-dopa biosynthetic process
+is_a: GO:2000283 {is_inferred="true"} ! negative regulation of cellular amino acid biosynthetic process
 
 [Term]
 id: GO:1903197 ! positive regulation of L-dopa biosynthetic process
-is_a: GO:0031328 {is_inferred="true"} ! positive regulation of cellular biosynthetic process
-is_a: GO:0051173 {is_inferred="true"} ! positive regulation of nitrogen compound metabolic process
 is_a: GO:1903195 {is_inferred="true"} ! regulation of L-dopa biosynthetic process
+is_a: GO:2000284 {is_inferred="true"} ! positive regulation of cellular amino acid biosynthetic process
 
 [Term]
 id: GO:1903198 ! regulation of L-dopa decarboxylase activity
@@ -78811,6 +79762,7 @@
 
 [Term]
 id: GO:1903222 ! quinolinic acid transmembrane transport
+is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
 is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
@@ -78933,20 +79885,17 @@
 
 [Term]
 id: GO:1903248 ! regulation of citrulline biosynthetic process
-is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
-is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
+is_a: GO:2000282 {is_inferred="true"} ! regulation of cellular amino acid biosynthetic process
 
 [Term]
 id: GO:1903249 ! negative regulation of citrulline biosynthetic process
-is_a: GO:0031327 {is_inferred="true"} ! negative regulation of cellular biosynthetic process
-is_a: GO:0051172 {is_inferred="true"} ! negative regulation of nitrogen compound metabolic process
 is_a: GO:1903248 {is_inferred="true"} ! regulation of citrulline biosynthetic process
+is_a: GO:2000283 {is_inferred="true"} ! negative regulation of cellular amino acid biosynthetic process
 
 [Term]
 id: GO:1903250 ! positive regulation of citrulline biosynthetic process
-is_a: GO:0031328 {is_inferred="true"} ! positive regulation of cellular biosynthetic process
-is_a: GO:0051173 {is_inferred="true"} ! positive regulation of nitrogen compound metabolic process
 is_a: GO:1903248 {is_inferred="true"} ! regulation of citrulline biosynthetic process
+is_a: GO:2000284 {is_inferred="true"} ! positive regulation of cellular amino acid biosynthetic process
 
 [Term]
 id: GO:1903251 ! multi-ciliated epithelial cell differentiation
@@ -79422,15 +80371,19 @@
 
 [Term]
 id: GO:1903350 ! response to dopamine
+is_a: GO:0060359 {is_inferred="true"} ! response to ammonium ion
 is_a: GO:0071869 {is_inferred="true"} ! response to catecholamine
 
 [Term]
 id: GO:1903351 ! cellular response to dopamine
+is_a: GO:0071242 {is_inferred="true"} ! cellular response to ammonium ion
 is_a: GO:0071870 {is_inferred="true"} ! cellular response to catecholamine stimulus
 is_a: GO:1903350 {is_inferred="true"} ! response to dopamine
 
 [Term]
 id: GO:1903352 ! L-ornithine transmembrane transport
+is_a: GO:0015822 {is_inferred="true"} ! ornithine transport
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
 
 [Term]
@@ -79682,6 +80635,7 @@
 
 [Term]
 id: GO:1903401 ! L-lysine transmembrane transport
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 is_a: GO:1902022 {is_inferred="true"} ! L-lysine transport
 is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
 
@@ -79735,6 +80689,7 @@
 
 [Term]
 id: GO:1903411 ! L-ornithine import into cell
+is_a: GO:0015822 {is_inferred="true"} ! ornithine transport
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 
 [Term]
@@ -79960,6 +80915,7 @@
 id: GO:1903457 ! lactate catabolic process
 is_a: GO:0006089 {is_inferred="true"} ! lactate metabolic process
 is_a: GO:0072329 {is_inferred="true"} ! monocarboxylic acid catabolic process
+is_a: GO:1901616 {is_inferred="true"} ! organic hydroxy compound catabolic process
 
 [Term]
 id: GO:1903459 ! mitotic DNA replication lagging strand elongation
@@ -80131,7 +81087,8 @@
 
 [Term]
 id: GO:1903492 ! response to acetylsalicylate
-is_a: GO:0010033 {is_inferred="true"} ! response to organic substance
+is_a: GO:0001101 {is_inferred="true"} ! response to acid chemical
+is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
 [Term]
@@ -80230,11 +81187,12 @@
 
 [Term]
 id: GO:1903511 ! orotic acid metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 is_a: GO:0072527 {is_inferred="true"} ! pyrimidine-containing compound metabolic process
 
 [Term]
 id: GO:1903512 ! phytanic acid metabolic process
+is_a: GO:0001676 {is_inferred="true"} ! long-chain fatty acid metabolic process
 is_a: GO:0097089 {is_inferred="true"} ! methyl-branched fatty acid metabolic process
 
 [Term]
@@ -80390,13 +81348,11 @@
 
 [Term]
 id: GO:1903544 ! response to butyrate
-is_a: GO:0033993 {is_inferred="true"} ! response to lipid
-is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
+is_a: GO:0070542 {is_inferred="true"} ! response to fatty acid
 
 [Term]
 id: GO:1903545 ! cellular response to butyrate
-is_a: GO:0071396 {is_inferred="true"} ! cellular response to lipid
-is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
+is_a: GO:0071398 {is_inferred="true"} ! cellular response to fatty acid
 is_a: GO:1903544 {is_inferred="true"} ! response to butyrate
 
 [Term]
@@ -80645,6 +81601,7 @@
 
 [Term]
 id: GO:1903593 ! regulation of histamine secretion by mast cell
+is_a: GO:0043269 {is_inferred="true"} ! regulation of ion transport
 is_a: GO:0043304 {is_inferred="true"} ! regulation of mast cell degranulation
 is_a: GO:0046883 {is_inferred="true"} ! regulation of hormone secretion
 is_a: GO:0050727 {is_inferred="true"} ! regulation of inflammatory response
@@ -80652,6 +81609,7 @@
 
 [Term]
 id: GO:1903594 ! negative regulation of histamine secretion by mast cell
+is_a: GO:0043271 {is_inferred="true"} ! negative regulation of ion transport
 is_a: GO:0043305 {is_inferred="true"} ! negative regulation of mast cell degranulation
 is_a: GO:0046888 {is_inferred="true"} ! negative regulation of hormone secretion
 is_a: GO:0050728 {is_inferred="true"} ! negative regulation of inflammatory response
@@ -80660,6 +81618,7 @@
 
 [Term]
 id: GO:1903595 ! positive regulation of histamine secretion by mast cell
+is_a: GO:0043270 {is_inferred="true"} ! positive regulation of ion transport
 is_a: GO:0043306 {is_inferred="true"} ! positive regulation of mast cell degranulation
 is_a: GO:0046887 {is_inferred="true"} ! positive regulation of hormone secretion
 is_a: GO:0050729 {is_inferred="true"} ! positive regulation of inflammatory response
@@ -80692,6 +81651,7 @@
 
 [Term]
 id: GO:1903601 ! thermospermine metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
 
 [Term]
@@ -81246,11 +82206,13 @@
 [Term]
 id: GO:1903710 ! spermine transmembrane transport
 is_a: GO:0000296 {is_inferred="true"} ! spermine transport
+is_a: GO:0072488 {is_inferred="true"} ! ammonium transmembrane transport
 is_a: GO:1902047 {is_inferred="true"} ! polyamine transmembrane transport
 
 [Term]
 id: GO:1903711 ! spermidine transmembrane transport
 is_a: GO:0015848 {is_inferred="true"} ! spermidine transport
+is_a: GO:0072488 {is_inferred="true"} ! ammonium transmembrane transport
 is_a: GO:1902047 {is_inferred="true"} ! polyamine transmembrane transport
 
 [Term]
@@ -81257,16 +82219,19 @@
 id: GO:1903712 ! cysteine transmembrane transport
 is_a: GO:0003333 {is_inferred="true"} ! amino acid transmembrane transport
 is_a: GO:0042883 {is_inferred="true"} ! cysteine transport
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 
 [Term]
 id: GO:1903713 ! asparagine transmembrane transport
 is_a: GO:0003333 {is_inferred="true"} ! amino acid transmembrane transport
-is_a: GO:0042886 {is_inferred="true"} ! amide transport
+is_a: GO:0006867 {is_inferred="true"} ! asparagine transport
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 
 [Term]
 id: GO:1903714 ! isoleucine transmembrane transport
 is_a: GO:0003333 {is_inferred="true"} ! amino acid transmembrane transport
 is_a: GO:0015818 {is_inferred="true"} ! isoleucine transport
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 
 [Term]
 id: GO:1903715 ! regulation of aerobic respiration
@@ -81582,7 +82547,8 @@
 
 [Term]
 id: GO:1903785 ! L-valine transmembrane transport
-is_a: GO:0015803 {is_inferred="true"} ! branched-chain amino acid transport
+is_a: GO:0015829 {is_inferred="true"} ! valine transport
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
 
 [Term]
@@ -81607,8 +82573,8 @@
 
 [Term]
 id: GO:1903789 ! regulation of amino acid transmembrane transport
-is_a: GO:0034762 {is_inferred="true"} ! regulation of transmembrane transport
 is_a: GO:0051955 {is_inferred="true"} ! regulation of amino acid transport
+is_a: GO:1903959 {is_inferred="true"} ! regulation of anion transmembrane transport
 
 [Term]
 id: GO:1903790 ! guanine nucleotide transmembrane transport
@@ -81706,6 +82672,7 @@
 
 [Term]
 id: GO:1903809 ! L-proline import into cell
+is_a: GO:0015824 {is_inferred="true"} ! proline transport
 is_a: GO:0043092 {is_inferred="true"} ! L-amino acid import
 
 [Term]
@@ -81775,6 +82742,8 @@
 [Term]
 id: GO:1903826 ! arginine transmembrane transport
 is_a: GO:0003333 {is_inferred="true"} ! amino acid transmembrane transport
+is_a: GO:0015809 {is_inferred="true"} ! arginine transport
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 
 [Term]
 id: GO:1903827 ! regulation of cellular protein localization
@@ -81827,10 +82796,12 @@
 
 [Term]
 id: GO:1903840 ! response to arsenite(3-)
+is_a: GO:0001101 {is_inferred="true"} ! response to acid chemical
 is_a: GO:1903842 {is_inferred="true"} ! response to arsenite ion
 
 [Term]
 id: GO:1903841 ! cellular response to arsenite(3-)
+is_a: GO:0071229 {is_inferred="true"} ! cellular response to acid chemical
 is_a: GO:1903840 {is_inferred="true"} ! response to arsenite(3-)
 is_a: GO:1903843 {is_inferred="true"} ! cellular response to arsenite ion
 
@@ -82246,11 +83217,12 @@
 
 [Term]
 id: GO:1903927 ! response to cyanide
-is_a: GO:0042221 {is_inferred="true"} ! response to chemical
+is_a: GO:0001101 {is_inferred="true"} ! response to acid chemical
+is_a: GO:0010033 {is_inferred="true"} ! response to organic substance
 
 [Term]
 id: GO:1903928 ! cellular response to cyanide
-is_a: GO:0070887 {is_inferred="true"} ! cellular response to chemical stimulus
+is_a: GO:0071229 {is_inferred="true"} ! cellular response to acid chemical
 is_a: GO:1903927 {is_inferred="true"} ! response to cyanide
 
 [Term]
@@ -82454,7 +83426,7 @@
 
 [Term]
 id: GO:1903962 ! arachidonate transporter activity
-is_a: GO:0005319 {is_inferred="true"} ! lipid transporter activity
+is_a: GO:0005324 {is_inferred="true"} ! long-chain fatty acid transporter activity
 
 [Term]
 id: GO:1903963 ! arachidonate transport
@@ -82463,19 +83435,16 @@
 
 [Term]
 id: GO:1903964 ! monounsaturated fatty acid metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
-is_a: GO:0006629 {is_inferred="true"} ! lipid metabolic process
+is_a: GO:0033559 {is_inferred="true"} ! unsaturated fatty acid metabolic process
 
 [Term]
 id: GO:1903965 ! monounsaturated fatty acid catabolic process
-is_a: GO:0016042 {is_inferred="true"} ! lipid catabolic process
-is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
+is_a: GO:0009062 {is_inferred="true"} ! fatty acid catabolic process
 is_a: GO:1903964 {is_inferred="true"} ! monounsaturated fatty acid metabolic process
 
 [Term]
 id: GO:1903966 ! monounsaturated fatty acid biosynthetic process
-is_a: GO:0008610 {is_inferred="true"} ! lipid biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
+is_a: GO:0006636 {is_inferred="true"} ! unsaturated fatty acid biosynthetic process
 is_a: GO:1903964 {is_inferred="true"} ! monounsaturated fatty acid metabolic process
 
 [Term]
@@ -82553,6 +83522,7 @@
 
 [Term]
 id: GO:1903981 ! enterobactin binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
 
@@ -82675,11 +83645,13 @@
 [Term]
 id: GO:1904014 ! response to serotonin
 is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
+is_a: GO:0060359 {is_inferred="true"} ! response to ammonium ion
 is_a: GO:0071867 {is_inferred="true"} ! response to monoamine
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
 [Term]
 id: GO:1904015 ! cellular response to serotonin
+is_a: GO:0071242 {is_inferred="true"} ! cellular response to ammonium ion
 is_a: GO:0071407 {is_inferred="true"} ! cellular response to organic cyclic compound
 is_a: GO:0071868 {is_inferred="true"} ! cellular response to monoamine stimulus
 is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
@@ -84575,6 +85547,7 @@
 [Term]
 id: GO:1904399 ! heparan sulfate binding
 is_a: GO:0005539 {is_inferred="true"} ! glycosaminoglycan binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:1901681 {is_inferred="true"} ! sulfur compound binding
 
 [Term]
@@ -84838,7 +85811,6 @@
 
 [Term]
 id: GO:1904448 ! regulation of aspartate secretion
-is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
 is_a: GO:0051955 {is_inferred="true"} ! regulation of amino acid transport
 is_a: GO:1903530 {is_inferred="true"} ! regulation of secretion by cell
 
@@ -84846,7 +85818,6 @@
 id: GO:1904449 ! negative regulation of aspartate secretion
 is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
 is_a: GO:1903531 {is_inferred="true"} ! negative regulation of secretion by cell
-is_a: GO:1903792 {is_inferred="true"} ! negative regulation of anion transport
 is_a: GO:1904448 {is_inferred="true"} ! regulation of aspartate secretion
 
 [Term]
@@ -84853,7 +85824,6 @@
 id: GO:1904450 ! positive regulation of aspartate secretion
 is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
 is_a: GO:1903532 {is_inferred="true"} ! positive regulation of secretion by cell
-is_a: GO:1903793 {is_inferred="true"} ! positive regulation of anion transport
 is_a: GO:1904448 {is_inferred="true"} ! regulation of aspartate secretion
 
 [Term]
@@ -85009,11 +85979,16 @@
 
 [Term]
 id: GO:1904481 ! response to tetrahydrofolate
-is_a: GO:0010033 {is_inferred="true"} ! response to organic substance
+is_a: GO:0001101 {is_inferred="true"} ! response to acid chemical
+is_a: GO:0010243 {is_inferred="true"} ! response to organonitrogen compound
+is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
 [Term]
 id: GO:1904482 ! cellular response to tetrahydrofolate
+is_a: GO:0071229 {is_inferred="true"} ! cellular response to acid chemical
+is_a: GO:0071407 {is_inferred="true"} ! cellular response to organic cyclic compound
+is_a: GO:0071417 {is_inferred="true"} ! cellular response to organonitrogen compound
 is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
 is_a: GO:1904481 {is_inferred="true"} ! response to tetrahydrofolate
 
@@ -85060,6 +86035,7 @@
 
 [Term]
 id: GO:1904492 ! Ac-Asp-Glu binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:1900750 {is_inferred="true"} ! oligopeptide binding
 
 [Term]
@@ -85353,10 +86329,13 @@
 [Term]
 id: GO:1904556 ! L-tryptophan transmembrane transport
 is_a: GO:0015827 {is_inferred="true"} ! tryptophan transport
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
 
 [Term]
 id: GO:1904557 ! L-alanine transmembrane transport
+is_a: GO:0015808 {is_inferred="true"} ! L-alanine transport
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
 
 [Term]
@@ -85503,9 +86482,11 @@
 [Term]
 id: GO:1904585 ! response to putrescine
 is_a: GO:0010243 {is_inferred="true"} ! response to organonitrogen compound
+is_a: GO:0060359 {is_inferred="true"} ! response to ammonium ion
 
 [Term]
 id: GO:1904586 ! cellular response to putrescine
+is_a: GO:0071242 {is_inferred="true"} ! cellular response to ammonium ion
 is_a: GO:0071417 {is_inferred="true"} ! cellular response to organonitrogen compound
 is_a: GO:1904585 {is_inferred="true"} ! response to putrescine
 
@@ -85540,7 +86521,8 @@
 
 [Term]
 id: GO:1904593 ! prostaglandin binding
-is_a: GO:1901567 {is_inferred="true"} ! fatty acid derivative binding
+is_a: GO:0005504 {is_inferred="true"} ! fatty acid binding
+is_a: GO:0050542 {is_inferred="true"} ! icosanoid binding
 
 [Term]
 id: GO:1904594 ! regulation of termination of RNA polymerase II transcription
@@ -86388,8 +87370,7 @@
 
 [Term]
 id: GO:1904767 ! octanoic acid binding
-is_a: GO:0008289 {is_inferred="true"} ! lipid binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
+is_a: GO:0005504 {is_inferred="true"} ! fatty acid binding
 
 [Term]
 id: GO:1904768 ! all-trans-retinol binding
@@ -86397,8 +87378,7 @@
 
 [Term]
 id: GO:1904769 ! isopentadecanoic acid binding
-is_a: GO:0008289 {is_inferred="true"} ! lipid binding
-is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
+is_a: GO:0036041 {is_inferred="true"} ! long-chain fatty acid binding
 
 [Term]
 id: GO:1904770 ! intramembranous bone morphogenesis
@@ -87275,7 +88255,7 @@
 
 [Term]
 id: GO:1904952 ! hydroxycinnamic acid transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
+is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
 
 [Term]
 id: GO:1904953 ! Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation
@@ -87436,6 +88416,8 @@
 
 [Term]
 id: GO:1904983 ! transmembrane glycine transport from cytosol to mitochondrion
+is_a: GO:0015816 {is_inferred="true"} ! glycine transport
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
@@ -87442,15 +88424,18 @@
 [Term]
 id: GO:1904984 ! regulation of quinolinate biosynthetic process
 is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
+is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
 
 [Term]
 id: GO:1904985 ! negative regulation of quinolinate biosynthetic process
 is_a: GO:0031327 {is_inferred="true"} ! negative regulation of cellular biosynthetic process
+is_a: GO:0051172 {is_inferred="true"} ! negative regulation of nitrogen compound metabolic process
 is_a: GO:1904984 {is_inferred="true"} ! regulation of quinolinate biosynthetic process
 
 [Term]
 id: GO:1904986 ! positive regulation of quinolinate biosynthetic process
 is_a: GO:0031328 {is_inferred="true"} ! positive regulation of cellular biosynthetic process
+is_a: GO:0051173 {is_inferred="true"} ! positive regulation of nitrogen compound metabolic process
 is_a: GO:1904984 {is_inferred="true"} ! regulation of quinolinate biosynthetic process
 
 [Term]
@@ -87529,14 +88514,14 @@
 
 [Term]
 id: GO:1905003 ! picolinic acid metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
 is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
+is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 is_a: GO:0072524 {is_inferred="true"} ! pyridine-containing compound metabolic process
 
 [Term]
 id: GO:1905004 ! picolinic acid biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
 is_a: GO:0019438 {is_inferred="true"} ! aromatic compound biosynthetic process
+is_a: GO:0072330 {is_inferred="true"} ! monocarboxylic acid biosynthetic process
 is_a: GO:0072525 {is_inferred="true"} ! pyridine-containing compound biosynthetic process
 is_a: GO:1905003 {is_inferred="true"} ! picolinic acid metabolic process
 
@@ -87583,7 +88568,7 @@
 [Term]
 id: GO:1905013 ! negative regulation of 'de novo' NAD biosynthetic process from tryptophan
 is_a: GO:0030809 {is_inferred="true"} ! negative regulation of nucleotide biosynthetic process
-is_a: GO:0033239 {is_inferred="true"} ! negative regulation of cellular amine metabolic process
+is_a: GO:0045763 {is_inferred="true"} ! negative regulation of cellular amino acid metabolic process
 is_a: GO:1902689 {is_inferred="true"} ! negative regulation of NAD metabolic process
 is_a: GO:1905012 {is_inferred="true"} ! regulation of 'de novo' NAD biosynthetic process from tryptophan
 
@@ -87725,6 +88710,8 @@
 
 [Term]
 id: GO:1905039 ! carboxylic acid transmembrane transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 is_a: GO:1903825 {is_inferred="true"} ! organic acid transmembrane transport
 
 [Term]
@@ -88192,6 +89179,7 @@
 
 [Term]
 id: GO:1905135 ! biotin import across plasma membrane
+is_a: GO:0035461 {is_inferred="true"} ! vitamin transmembrane transport
 is_a: GO:0044756 {is_inferred="true"} ! biotin import into cell
 is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
 is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
@@ -88504,6 +89492,7 @@
 
 [Term]
 id: GO:1905200 ! gibberellic acid transmembrane transport
+is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
 is_a: GO:0046865 {is_inferred="true"} ! terpenoid transport
 is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
@@ -88663,13 +89652,16 @@
 [Term]
 id: GO:1905232 ! cellular response to L-glutamate
 is_a: GO:0071230 {is_inferred="true"} ! cellular response to amino acid stimulus
+is_a: GO:1902065 {is_inferred="true"} ! response to L-glutamate
 
 [Term]
 id: GO:1905233 ! response to codeine
 is_a: GO:0014072 {is_inferred="true"} ! response to isoquinoline alkaloid
+is_a: GO:0060359 {is_inferred="true"} ! response to ammonium ion
 
 [Term]
 id: GO:1905234 ! cellular response to codeine
+is_a: GO:0071242 {is_inferred="true"} ! cellular response to ammonium ion
 is_a: GO:0071317 {is_inferred="true"} ! cellular response to isoquinoline alkaloid
 is_a: GO:1905233 {is_inferred="true"} ! response to codeine
 
@@ -89140,6 +90132,7 @@
 
 [Term]
 id: GO:1905329 ! sphingoid long-chain base transport
+is_a: GO:0006869 {is_inferred="true"} ! lipid transport
 is_a: GO:0015695 {is_inferred="true"} ! organic cation transport
 is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 
@@ -89212,6 +90205,8 @@
 
 [Term]
 id: GO:1905344 ! prostaglandin catabolic process
+is_a: GO:0006693 {is_inferred="true"} ! prostaglandin metabolic process
+is_a: GO:0009062 {is_inferred="true"} ! fatty acid catabolic process
 is_a: GO:1901523 {is_inferred="true"} ! icosanoid catabolic process
 
 [Term]
@@ -89501,18 +90496,21 @@
 
 [Term]
 id: GO:1905407 ! regulation of creatine transmembrane transporter activity
-is_a: GO:0022898 {is_inferred="true"} ! regulation of transmembrane transporter activity
+is_a: GO:0032412 {is_inferred="true"} ! regulation of ion transmembrane transporter activity
+is_a: GO:1903789 {is_inferred="true"} ! regulation of amino acid transmembrane transport
 
 [Term]
 id: GO:1905408 ! negative regulation of creatine transmembrane transporter activity
-is_a: GO:0032410 {is_inferred="true"} ! negative regulation of transporter activity
-is_a: GO:0034763 {is_inferred="true"} ! negative regulation of transmembrane transport
+is_a: GO:0032413 {is_inferred="true"} ! negative regulation of ion transmembrane transporter activity
+is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
+is_a: GO:1903960 {is_inferred="true"} ! negative regulation of anion transmembrane transport
 is_a: GO:1905407 {is_inferred="true"} ! regulation of creatine transmembrane transporter activity
 
 [Term]
 id: GO:1905409 ! positive regulation of creatine transmembrane transporter activity
-is_a: GO:0032411 {is_inferred="true"} ! positive regulation of transporter activity
-is_a: GO:0034764 {is_inferred="true"} ! positive regulation of transmembrane transport
+is_a: GO:0032414 {is_inferred="true"} ! positive regulation of ion transmembrane transporter activity
+is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
+is_a: GO:1903961 {is_inferred="true"} ! positive regulation of anion transmembrane transport
 is_a: GO:1905407 {is_inferred="true"} ! regulation of creatine transmembrane transporter activity
 
 [Term]
@@ -89662,11 +90660,13 @@
 
 [Term]
 id: GO:1905439 ! response to chondroitin 6'-sulfate
+is_a: GO:0001101 {is_inferred="true"} ! response to acid chemical
 is_a: GO:0010243 {is_inferred="true"} ! response to organonitrogen compound
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
 [Term]
 id: GO:1905440 ! cellular response to chondroitin 6'-sulfate
+is_a: GO:0071229 {is_inferred="true"} ! cellular response to acid chemical
 is_a: GO:0071417 {is_inferred="true"} ! cellular response to organonitrogen compound
 is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
 is_a: GO:1905439 {is_inferred="true"} ! response to chondroitin 6'-sulfate
@@ -89673,11 +90673,13 @@
 
 [Term]
 id: GO:1905441 ! response to chondroitin 4'-sulfate
+is_a: GO:0001101 {is_inferred="true"} ! response to acid chemical
 is_a: GO:0010243 {is_inferred="true"} ! response to organonitrogen compound
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
 [Term]
 id: GO:1905442 ! cellular response to chondroitin 4'-sulfate
+is_a: GO:0071229 {is_inferred="true"} ! cellular response to acid chemical
 is_a: GO:0071417 {is_inferred="true"} ! cellular response to organonitrogen compound
 is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
 is_a: GO:1905441 {is_inferred="true"} ! response to chondroitin 4'-sulfate
@@ -89959,6 +90961,7 @@
 
 [Term]
 id: GO:1905502 ! acetyl-CoA binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:1901681 {is_inferred="true"} ! sulfur compound binding
 
 [Term]
@@ -90097,17 +91100,20 @@
 id: GO:1905532 ! regulation of leucine import across plasma membrane
 is_a: GO:1903128 {is_inferred="true"} ! regulation of leucine import into cell
 is_a: GO:1903789 {is_inferred="true"} ! regulation of amino acid transmembrane transport
+is_a: GO:1904062 {is_inferred="true"} ! regulation of cation transmembrane transport
 
 [Term]
 id: GO:1905533 ! negative regulation of leucine import across plasma membrane
-is_a: GO:0034763 {is_inferred="true"} ! negative regulation of transmembrane transport
 is_a: GO:1903129 {is_inferred="true"} ! negative regulation of leucine import into cell
+is_a: GO:1903960 {is_inferred="true"} ! negative regulation of anion transmembrane transport
+is_a: GO:1904063 {is_inferred="true"} ! negative regulation of cation transmembrane transport
 is_a: GO:1905532 {is_inferred="true"} ! regulation of leucine import across plasma membrane
 
 [Term]
 id: GO:1905534 ! positive regulation of leucine import across plasma membrane
-is_a: GO:0034764 {is_inferred="true"} ! positive regulation of transmembrane transport
 is_a: GO:1903130 {is_inferred="true"} ! positive regulation of leucine import into cell
+is_a: GO:1903961 {is_inferred="true"} ! positive regulation of anion transmembrane transport
+is_a: GO:1904064 {is_inferred="true"} ! positive regulation of cation transmembrane transport
 is_a: GO:1905532 {is_inferred="true"} ! regulation of leucine import across plasma membrane
 
 [Term]
@@ -90141,11 +91147,13 @@
 id: GO:1905541 ! regulation of L-arginine import across plasma membrane
 is_a: GO:1902826 {is_inferred="true"} ! regulation of L-arginine import into cell
 is_a: GO:1903789 {is_inferred="true"} ! regulation of amino acid transmembrane transport
+is_a: GO:1904062 {is_inferred="true"} ! regulation of cation transmembrane transport
 
 [Term]
 id: GO:1905542 ! negative regulation of L-arginine import across plasma membrane
-is_a: GO:0034763 {is_inferred="true"} ! negative regulation of transmembrane transport
 is_a: GO:1902827 {is_inferred="true"} ! negative regulation of L-arginine import into cell
+is_a: GO:1903960 {is_inferred="true"} ! negative regulation of anion transmembrane transport
+is_a: GO:1904063 {is_inferred="true"} ! negative regulation of cation transmembrane transport
 is_a: GO:1905541 {is_inferred="true"} ! regulation of L-arginine import across plasma membrane
 
 [Term]
@@ -90156,6 +91164,7 @@
 [Term]
 id: GO:1905544 ! L-methionine import across plasma membrane
 is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
 is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
 is_a: GO:1903813 {is_inferred="true"} ! L-methionine import into cell
 
@@ -90287,21 +91296,26 @@
 id: GO:1905572 ! ganglioside GM1 transport to membrane
 is_a: GO:0035627 {is_inferred="true"} ! ceramide transport
 is_a: GO:0046836 {is_inferred="true"} ! glycolipid transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
 
 [Term]
 id: GO:1905573 ! ganglioside GM1 binding
+is_a: GO:0031406 {is_inferred="true"} ! carboxylic acid binding
 is_a: GO:0035594 {is_inferred="true"} ! ganglioside binding
 
 [Term]
 id: GO:1905574 ! ganglioside GM2 binding
+is_a: GO:0031406 {is_inferred="true"} ! carboxylic acid binding
 is_a: GO:0035594 {is_inferred="true"} ! ganglioside binding
 
 [Term]
 id: GO:1905575 ! ganglioside GM3 binding
+is_a: GO:0033293 {is_inferred="true"} ! monocarboxylic acid binding
 is_a: GO:0035594 {is_inferred="true"} ! ganglioside binding
 
 [Term]
 id: GO:1905576 ! ganglioside GT1b binding
+is_a: GO:0031406 {is_inferred="true"} ! carboxylic acid binding
 is_a: GO:0035594 {is_inferred="true"} ! ganglioside binding
 
 [Term]
@@ -90364,8 +91378,9 @@
 
 [Term]
 id: GO:1905589 ! positive regulation of L-arginine import across plasma membrane
-is_a: GO:0034764 {is_inferred="true"} ! positive regulation of transmembrane transport
 is_a: GO:1902828 {is_inferred="true"} ! positive regulation of L-arginine import into cell
+is_a: GO:1903961 {is_inferred="true"} ! positive regulation of anion transmembrane transport
+is_a: GO:1904064 {is_inferred="true"} ! positive regulation of cation transmembrane transport
 is_a: GO:1905541 {is_inferred="true"} ! regulation of L-arginine import across plasma membrane
 
 [Term]
@@ -90540,17 +91555,20 @@
 id: GO:1905624 ! regulation of L-methionine import across plasma membrane
 is_a: GO:0010958 {is_inferred="true"} ! regulation of amino acid import
 is_a: GO:1903789 {is_inferred="true"} ! regulation of amino acid transmembrane transport
+is_a: GO:1904062 {is_inferred="true"} ! regulation of cation transmembrane transport
 
 [Term]
 id: GO:1905625 ! negative regulation of L-methionine import across plasma membrane
-is_a: GO:0034763 {is_inferred="true"} ! negative regulation of transmembrane transport
 is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
+is_a: GO:1903960 {is_inferred="true"} ! negative regulation of anion transmembrane transport
+is_a: GO:1904063 {is_inferred="true"} ! negative regulation of cation transmembrane transport
 is_a: GO:1905624 {is_inferred="true"} ! regulation of L-methionine import across plasma membrane
 
 [Term]
 id: GO:1905626 ! positive regulation of L-methionine import across plasma membrane
-is_a: GO:0034764 {is_inferred="true"} ! positive regulation of transmembrane transport
 is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
+is_a: GO:1903961 {is_inferred="true"} ! positive regulation of anion transmembrane transport
+is_a: GO:1904064 {is_inferred="true"} ! positive regulation of cation transmembrane transport
 is_a: GO:1905624 {is_inferred="true"} ! regulation of L-methionine import across plasma membrane
 
 [Term]
@@ -90881,19 +91899,16 @@
 
 [Term]
 id: GO:1905693 ! regulation of phosphatidic acid biosynthetic process
-is_a: GO:0009889 {is_inferred="true"} ! regulation of biosynthetic process
-is_a: GO:0051174 {is_inferred="true"} ! regulation of phosphorus metabolic process
+is_a: GO:0071071 {is_inferred="true"} ! regulation of phospholipid biosynthetic process
 
 [Term]
 id: GO:1905694 ! negative regulation of phosphatidic acid biosynthetic process
-is_a: GO:0009890 {is_inferred="true"} ! negative regulation of biosynthetic process
-is_a: GO:0010563 {is_inferred="true"} ! negative regulation of phosphorus metabolic process
+is_a: GO:0071072 {is_inferred="true"} ! negative regulation of phospholipid biosynthetic process
 is_a: GO:1905693 {is_inferred="true"} ! regulation of phosphatidic acid biosynthetic process
 
 [Term]
 id: GO:1905695 ! positive regulation of phosphatidic acid biosynthetic process
-is_a: GO:0009891 {is_inferred="true"} ! positive regulation of biosynthetic process
-is_a: GO:0010562 {is_inferred="true"} ! positive regulation of phosphorus metabolic process
+is_a: GO:0071073 {is_inferred="true"} ! positive regulation of phospholipid biosynthetic process
 is_a: GO:1905693 {is_inferred="true"} ! regulation of phosphatidic acid biosynthetic process
 
 [Term]
@@ -91101,8 +92116,8 @@
 
 [Term]
 id: GO:1990123 ! L-glutamate import into cell
-is_a: GO:0015813 {is_inferred="true"} ! L-glutamate transport
-is_a: GO:0098657 {is_inferred="true"} ! import into cell
+is_a: GO:1902837 {is_inferred="true"} ! amino acid import into cell
+is_a: GO:1903802 {is_inferred="true"} ! L-glutamate(1-) import into cell
 
 [Term]
 id: GO:1990126 ! retrograde transport, endosome to plasma membrane
@@ -91528,8 +92543,7 @@
 [Term]
 id: GO:1990541 ! mitochondrial citrate transmembrane transport
 is_a: GO:0006843 {is_inferred="true"} ! mitochondrial citrate transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
+is_a: GO:1990546 {is_inferred="true"} ! mitochondrial tricarboxylic acid transmembrane transport
 
 [Term]
 id: GO:1990543 ! mitochondrial S-adenosyl-L-methionine transmembrane transport
@@ -91538,6 +92552,7 @@
 [Term]
 id: GO:1990544 ! mitochondrial ATP transmembrane transport
 is_a: GO:0015860 {is_inferred="true"} ! purine nucleoside transmembrane transport
+is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 is_a: GO:1901679 {is_inferred="true"} ! nucleotide transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
@@ -91544,6 +92559,8 @@
 [Term]
 id: GO:1990545 ! mitochondrial thiamine pyrophosphate transmembrane transport
 is_a: GO:0072531 {is_inferred="true"} ! pyrimidine-containing compound transmembrane transport
+is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
+is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
@@ -91566,12 +92583,12 @@
 [Term]
 id: GO:1990550 ! mitochondrial alpha-ketoglutarate transmembrane transport
 is_a: GO:0015742 {is_inferred="true"} ! alpha-ketoglutarate transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:1990551 ! mitochondrial 2-oxoadipate transmembrane transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
@@ -91598,8 +92615,7 @@
 
 [Term]
 id: GO:1990558 ! mitochondrial malonate(1-) transmembrane transport
-is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:1901553 {is_inferred="true"} ! malonic acid transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
@@ -91619,6 +92635,7 @@
 [Term]
 id: GO:1990569 ! UDP-N-acetylglucosamine transmembrane transport
 is_a: GO:0090481 {is_inferred="true"} ! pyrimidine nucleotide-sugar transmembrane transport
+is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
 id: GO:1990573 ! potassium ion import across plasma membrane
@@ -91627,7 +92644,6 @@
 
 [Term]
 id: GO:1990575 ! mitochondrial L-ornithine transmembrane transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
@@ -92404,10 +93420,12 @@
 id: GO:2000082 ! regulation of L-ascorbic acid biosynthetic process
 is_a: GO:0030656 {is_inferred="true"} ! regulation of vitamin metabolic process
 is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
+is_a: GO:0043255 {is_inferred="true"} ! regulation of carbohydrate biosynthetic process
 
 [Term]
 id: GO:2000083 ! negative regulation of L-ascorbic acid biosynthetic process
 is_a: GO:0031327 {is_inferred="true"} ! negative regulation of cellular biosynthetic process
+is_a: GO:0045912 {is_inferred="true"} ! negative regulation of carbohydrate metabolic process
 is_a: GO:0046137 {is_inferred="true"} ! negative regulation of vitamin metabolic process
 is_a: GO:2000082 {is_inferred="true"} ! regulation of L-ascorbic acid biosynthetic process
 
@@ -92951,11 +93969,13 @@
 [Term]
 id: GO:2000191 ! regulation of fatty acid transport
 is_a: GO:0032368 {is_inferred="true"} ! regulation of lipid transport
+is_a: GO:0032890 {is_inferred="true"} ! regulation of organic acid transport
 is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
 
 [Term]
 id: GO:2000192 ! negative regulation of fatty acid transport
 is_a: GO:0032369 {is_inferred="true"} ! negative regulation of lipid transport
+is_a: GO:0032891 {is_inferred="true"} ! negative regulation of organic acid transport
 is_a: GO:1903792 {is_inferred="true"} ! negative regulation of anion transport
 is_a: GO:2000191 {is_inferred="true"} ! regulation of fatty acid transport
 
@@ -92962,6 +93982,7 @@
 [Term]
 id: GO:2000193 ! positive regulation of fatty acid transport
 is_a: GO:0032370 {is_inferred="true"} ! positive regulation of lipid transport
+is_a: GO:0032892 {is_inferred="true"} ! positive regulation of organic acid transport
 is_a: GO:1903793 {is_inferred="true"} ! positive regulation of anion transport
 is_a: GO:2000191 {is_inferred="true"} ! regulation of fatty acid transport
 
@@ -93061,20 +94082,17 @@
 
 [Term]
 id: GO:2000212 ! negative regulation of glutamate metabolic process
-is_a: GO:0031324 {is_inferred="true"} ! negative regulation of cellular metabolic process
-is_a: GO:0051172 {is_inferred="true"} ! negative regulation of nitrogen compound metabolic process
+is_a: GO:0045763 {is_inferred="true"} ! negative regulation of cellular amino acid metabolic process
 is_a: GO:2000211 {is_inferred="true"} ! regulation of glutamate metabolic process
 
 [Term]
 id: GO:2000213 ! positive regulation of glutamate metabolic process
-is_a: GO:0031325 {is_inferred="true"} ! positive regulation of cellular metabolic process
-is_a: GO:0051173 {is_inferred="true"} ! positive regulation of nitrogen compound metabolic process
+is_a: GO:0045764 {is_inferred="true"} ! positive regulation of cellular amino acid metabolic process
 is_a: GO:2000211 {is_inferred="true"} ! regulation of glutamate metabolic process
 
 [Term]
 id: GO:2000214 ! regulation of proline metabolic process
 is_a: GO:0000820 {is_inferred="true"} ! regulation of glutamine family amino acid metabolic process
-is_a: GO:0006521 {is_inferred="true"} ! regulation of cellular amino acid metabolic process
 
 [Term]
 id: GO:2000215 ! negative regulation of proline metabolic process
@@ -94475,19 +95493,16 @@
 
 [Term]
 id: GO:2000485 ! regulation of glutamine transport
-is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
 is_a: GO:0051955 {is_inferred="true"} ! regulation of amino acid transport
 
 [Term]
 id: GO:2000486 ! negative regulation of glutamine transport
 is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
-is_a: GO:1903792 {is_inferred="true"} ! negative regulation of anion transport
 is_a: GO:2000485 {is_inferred="true"} ! regulation of glutamine transport
 
 [Term]
 id: GO:2000487 ! positive regulation of glutamine transport
 is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
-is_a: GO:1903793 {is_inferred="true"} ! positive regulation of anion transport
 is_a: GO:2000485 {is_inferred="true"} ! regulation of glutamine transport
 
 [Term]
@@ -97465,6 +98480,10 @@
 is_a: GO:0030247 {is_inferred="true"} ! polysaccharide binding
 
 [Term]
+id: GO:2001080 ! chitosan binding
+is_a: GO:0070405 {is_inferred="true"} ! ammonium ion binding
+
+[Term]
 id: GO:2001081 ! (1->4)-beta-D-galactan binding
 is_a: GO:0030247 {is_inferred="true"} ! polysaccharide binding
 
@@ -97648,6 +98667,7 @@
 id: GO:2001121 ! coenzyme gamma-F420-2 biosynthetic process
 is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
 is_a: GO:0052649 {is_inferred="true"} ! coenzyme gamma-F420-2 metabolic process
+is_a: GO:0072351 {is_inferred="true"} ! tricarboxylic acid biosynthetic process
 is_a: GO:0090407 {is_inferred="true"} ! organophosphate biosynthetic process
 is_a: GO:1901137 {is_inferred="true"} ! carbohydrate derivative biosynthetic process
 is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
@@ -97690,11 +98710,13 @@
 id: GO:2001129 ! methane biosynthetic process from dimethylamine
 is_a: GO:0009308 {is_inferred="true"} ! amine metabolic process
 is_a: GO:0015948 {is_inferred="true"} ! methanogenesis
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 
 [Term]
 id: GO:2001130 ! methane biosynthetic process from trimethylamine
 is_a: GO:0009308 {is_inferred="true"} ! amine metabolic process
 is_a: GO:0015948 {is_inferred="true"} ! methanogenesis
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 
 [Term]
 id: GO:2001131 ! methane biosynthetic process from dimethyl sulfide
@@ -97704,6 +98726,7 @@
 [Term]
 id: GO:2001132 ! methane biosynthetic process from 3-(methylthio)propionic acid
 is_a: GO:0006631 {is_inferred="true"} ! fatty acid metabolic process
+is_a: GO:0006790 {is_inferred="true"} ! sulfur compound metabolic process
 is_a: GO:0015948 {is_inferred="true"} ! methanogenesis
 
 [Term]
@@ -97732,15 +98755,18 @@
 [Term]
 id: GO:2001138 ! regulation of phospholipid transport
 is_a: GO:0032368 {is_inferred="true"} ! regulation of lipid transport
+is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
 
 [Term]
 id: GO:2001139 ! negative regulation of phospholipid transport
 is_a: GO:0032369 {is_inferred="true"} ! negative regulation of lipid transport
+is_a: GO:1903792 {is_inferred="true"} ! negative regulation of anion transport
 is_a: GO:2001138 {is_inferred="true"} ! regulation of phospholipid transport
 
 [Term]
 id: GO:2001140 ! positive regulation of phospholipid transport
 is_a: GO:0032370 {is_inferred="true"} ! positive regulation of lipid transport
+is_a: GO:1903793 {is_inferred="true"} ! positive regulation of anion transport
 is_a: GO:2001138 {is_inferred="true"} ! regulation of phospholipid transport
 
 [Term]
@@ -97752,9 +98778,11 @@
 [Term]
 id: GO:2001142 ! nicotinate transport
 is_a: GO:0015718 {is_inferred="true"} ! monocarboxylic acid transport
+is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
 id: GO:2001143 ! N-methylnicotinate transport
+is_a: GO:0015695 {is_inferred="true"} ! organic cation transport
 is_a: GO:0015697 {is_inferred="true"} ! quaternary ammonium group transport
 
 [Term]
@@ -98187,6 +99215,7 @@
 
 [Term]
 id: GO:2001227 ! quercitrin binding
+is_a: GO:0043168 {is_inferred="true"} ! anion binding
 is_a: GO:0097243 {is_inferred="true"} ! flavonoid binding
 
 [Term]
@@ -98294,13 +99323,11 @@
 
 [Term]
 id: GO:2001248 ! regulation of ammonia assimilation cycle
-is_a: GO:0006521 {is_inferred="true"} ! regulation of cellular amino acid metabolic process
 is_a: GO:0006808 {is_inferred="true"} ! regulation of nitrogen utilization
 is_a: GO:2000211 {is_inferred="true"} ! regulation of glutamate metabolic process
 
 [Term]
 id: GO:2001249 ! negative regulation of ammonia assimilation cycle
-is_a: GO:0045763 {is_inferred="true"} ! negative regulation of cellular amino acid metabolic process
 is_a: GO:0045847 {is_inferred="true"} ! negative regulation of nitrogen utilization
 is_a: GO:2000212 {is_inferred="true"} ! negative regulation of glutamate metabolic process
 is_a: GO:2001248 {is_inferred="true"} ! regulation of ammonia assimilation cycle
@@ -98307,7 +99334,6 @@
 
 [Term]
 id: GO:2001250 ! positive regulation of ammonia assimilation cycle
-is_a: GO:0045764 {is_inferred="true"} ! positive regulation of cellular amino acid metabolic process
 is_a: GO:0045848 {is_inferred="true"} ! positive regulation of nitrogen utilization
 is_a: GO:2000213 {is_inferred="true"} ! positive regulation of glutamate metabolic process
 is_a: GO:2001248 {is_inferred="true"} ! regulation of ammonia assimilation cycle
@@ -98514,6 +99540,7 @@
 [Term]
 id: GO:2001291 ! codeine metabolic process
 is_a: GO:0033076 {is_inferred="true"} ! isoquinoline alkaloid metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 is_a: GO:1901376 {is_inferred="true"} ! organic heteropentacyclic compound metabolic process
 
 [Term]
@@ -98561,24 +99588,24 @@
 
 [Term]
 id: GO:2001300 ! lipoxin metabolic process
-is_a: GO:1901568 {is_inferred="true"} ! fatty acid derivative metabolic process
+is_a: GO:0006690 {is_inferred="true"} ! icosanoid metabolic process
+is_a: GO:0033559 {is_inferred="true"} ! unsaturated fatty acid metabolic process
 
 [Term]
 id: GO:2001301 ! lipoxin biosynthetic process
-is_a: GO:1901570 {is_inferred="true"} ! fatty acid derivative biosynthetic process
+is_a: GO:0006636 {is_inferred="true"} ! unsaturated fatty acid biosynthetic process
+is_a: GO:0046456 {is_inferred="true"} ! icosanoid biosynthetic process
 is_a: GO:2001300 {is_inferred="true"} ! lipoxin metabolic process
 
 [Term]
 id: GO:2001302 ! lipoxin A4 metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
-is_a: GO:0006629 {is_inferred="true"} ! lipid metabolic process
+is_a: GO:0001676 {is_inferred="true"} ! long-chain fatty acid metabolic process
 is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
 is_a: GO:2001300 {is_inferred="true"} ! lipoxin metabolic process
 
 [Term]
 id: GO:2001303 ! lipoxin A4 biosynthetic process
-is_a: GO:0008610 {is_inferred="true"} ! lipid biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
+is_a: GO:0042759 {is_inferred="true"} ! long-chain fatty acid biosynthetic process
 is_a: GO:1901617 {is_inferred="true"} ! organic hydroxy compound biosynthetic process
 is_a: GO:2001301 {is_inferred="true"} ! lipoxin biosynthetic process
 is_a: GO:2001302 {is_inferred="true"} ! lipoxin A4 metabolic process
@@ -98585,8 +99612,7 @@
 
 [Term]
 id: GO:2001304 ! lipoxin B4 metabolic process
-is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
-is_a: GO:0006629 {is_inferred="true"} ! lipid metabolic process
+is_a: GO:0001676 {is_inferred="true"} ! long-chain fatty acid metabolic process
 is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
 is_a: GO:2001300 {is_inferred="true"} ! lipoxin metabolic process
 
@@ -98598,8 +99624,7 @@
 
 [Term]
 id: GO:2001306 ! lipoxin B4 biosynthetic process
-is_a: GO:0008610 {is_inferred="true"} ! lipid biosynthetic process
-is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
+is_a: GO:0042759 {is_inferred="true"} ! long-chain fatty acid biosynthetic process
 is_a: GO:1901617 {is_inferred="true"} ! organic hydroxy compound biosynthetic process
 is_a: GO:2001301 {is_inferred="true"} ! lipoxin biosynthetic process
 is_a: GO:2001304 {is_inferred="true"} ! lipoxin B4 metabolic process
@@ -98648,6 +99673,7 @@
 [Term]
 id: GO:2001313 ! UDP-4-deoxy-4-formamido-beta-L-arabinopyranose metabolic process
 is_a: GO:0006040 {is_inferred="true"} ! amino sugar metabolic process
+is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
 is_a: GO:0009225 {is_inferred="true"} ! nucleotide-sugar metabolic process
 
 [Term]
------------------------------------------------------------------------
r37058 | termgenie | 2016-11-17 13:09:42 -0800 (Thu, 17 Nov 2016) | 3 lines

TermGenie commit for user: vw reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37058)
+++ go_inferences.obo	(working copy)
@@ -90942,6 +90942,25 @@
 is_a: GO:1905702 {is_inferred="true"} ! regulation of inhibitory synapse assembly
 
 [Term]
+id: GO:1905705 ! cellular response to paclitaxel
+is_a: GO:0071396 {is_inferred="true"} ! cellular response to lipid
+is_a: GO:1901555 {is_inferred="true"} ! response to paclitaxel
+
+[Term]
+id: GO:1905706 ! regulation of mitochondrial ATP synthesis coupled proton transport
+is_a: GO:0010155 {is_inferred="true"} ! regulation of proton transport
+is_a: GO:0032386 {is_inferred="true"} ! regulation of intracellular transport
+is_a: GO:1904062 {is_inferred="true"} ! regulation of cation transmembrane transport
+is_a: GO:2001169 {is_inferred="true"} ! regulation of ATP biosynthetic process
+
+[Term]
+id: GO:1905707 ! negative regulation of mitochondrial ATP synthesis coupled proton transport
+is_a: GO:0032387 {is_inferred="true"} ! negative regulation of intracellular transport
+is_a: GO:1904063 {is_inferred="true"} ! negative regulation of cation transmembrane transport
+is_a: GO:1905706 {is_inferred="true"} ! regulation of mitochondrial ATP synthesis coupled proton transport
+is_a: GO:2001170 {is_inferred="true"} ! negative regulation of ATP biosynthetic process
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37055 | dph | 2016-11-17 11:25:19 -0800 (Thu, 17 Nov 2016) | 2 lines

Fixed up definitions of blood vessel branching regulation terms.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37055)
+++ go_inferences.obo	(working copy)
@@ -74304,7 +74304,7 @@
 is_a: GO:1903818 {is_inferred="true"} ! positive regulation of voltage-gated potassium channel activity
 
 [Term]
-id: GO:1902262 ! apoptotic process involved in patterning of blood vessels
+id: GO:1902262 ! apoptotic process involved in blood vessel morphogenesis
 is_a: GO:0060561 {is_inferred="true"} ! apoptotic process involved in morphogenesis
 
 [Term]
@@ -90193,22 +90193,22 @@
 is_a: GO:1905550 {is_inferred="true"} ! regulation of protein localization to endoplasmic reticulum
 
 [Term]
-id: GO:1905553 ! regulation of patterning of blood vessels
+id: GO:1905553 ! regulation of blood vessel branching
 is_a: GO:0045765 {is_inferred="true"} ! regulation of angiogenesis
 is_a: GO:0060688 {is_inferred="true"} ! regulation of morphogenesis of a branching structure
 is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 
 [Term]
-id: GO:1905554 ! negative regulation of patterning of blood vessels
+id: GO:1905554 ! negative regulation of vessel branching
 is_a: GO:0016525 {is_inferred="true"} ! negative regulation of angiogenesis
 is_a: GO:1905331 {is_inferred="true"} ! negative regulation of morphogenesis of an epithelium
-is_a: GO:1905553 {is_inferred="true"} ! regulation of patterning of blood vessels
+is_a: GO:1905553 {is_inferred="true"} ! regulation of blood vessel branching
 
 [Term]
-id: GO:1905555 ! positive regulation of patterning of blood vessels
+id: GO:1905555 ! positive regulation blood vessel branching
 is_a: GO:0045766 {is_inferred="true"} ! positive regulation of angiogenesis
 is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
-is_a: GO:1905553 {is_inferred="true"} ! regulation of patterning of blood vessels
+is_a: GO:1905553 {is_inferred="true"} ! regulation of blood vessel branching
 
 [Term]
 id: GO:1905556 ! ciliary vesicle assembly
------------------------------------------------------------------------
r37052 | dph | 2016-11-17 11:01:14 -0800 (Thu, 17 Nov 2016) | 2 lines

GH10355-closed

changes in entailments

------------------------------------------------------------------------
r37050 | dph | 2016-11-17 10:52:19 -0800 (Thu, 17 Nov 2016) | 2 lines

GH12438-closed.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37050)
+++ go_inferences.obo	(working copy)
@@ -798,7 +798,7 @@
 is_a: GO:0022414 {is_inferred="true"} ! reproductive process
 
 [Term]
-id: GO:0000751 ! mitotic cell cycle arrest in response to pheromone
+id: GO:0000751 ! mitotic cell cycle G1 arrest in response to pheromone
 is_a: GO:0022414 {is_inferred="true"} ! reproductive process
 
 [Term]
------------------------------------------------------------------------
r37035 | paola | 2016-11-17 01:55:14 -0800 (Thu, 17 Nov 2016) | 2 lines

GH MP: GO:0007288 - sperm axoneme assembly #12790 - closed - added sperm axoneme assembly part_of flagellated sperm motility

changes in entailments

------------------------------------------------------------------------
r37035 | paola | 2016-11-17 01:55:14 -0800 (Thu, 17 Nov 2016) | 2 lines

GH MP: GO:0007288 - sperm axoneme assembly #12790 - closed - added sperm axoneme assembly part_of flagellated sperm motility

changes in entailments

------------------------------------------------------------------------
r37035 | paola | 2016-11-17 01:55:14 -0800 (Thu, 17 Nov 2016) | 2 lines

GH MP: GO:0007288 - sperm axoneme assembly #12790 - closed - added sperm axoneme assembly part_of flagellated sperm motility

changes in entailments

------------------------------------------------------------------------
r37033 | paola | 2016-11-17 00:18:13 -0800 (Thu, 17 Nov 2016) | 2 lines

Stemming from GH NTR/OTR: multiciliation-related classes #12672 - work in progress - added 'parthenogenesis' as related synonym of 'asexual reproduction'

changes in entailments

------------------------------------------------------------------------
r37030 | termgenie | 2016-11-16 10:58:27 -0800 (Wed, 16 Nov 2016) | 4 lines

TermGenie commit for user: tb reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37030)
+++ go_inferences.obo	(working copy)
@@ -90928,6 +90928,20 @@
 is_a: GO:2001025 {is_inferred="true"} ! positive regulation of response to drug
 
 [Term]
+id: GO:1905702 ! regulation of inhibitory synapse assembly
+is_a: GO:0051963 {is_inferred="true"} ! regulation of synapse assembly
+
+[Term]
+id: GO:1905703 ! negative regulation of inhibitory synapse assembly
+is_a: GO:0051964 {is_inferred="true"} ! negative regulation of synapse assembly
+is_a: GO:1905702 {is_inferred="true"} ! regulation of inhibitory synapse assembly
+
+[Term]
+id: GO:1905704 ! positive regulation of inhibitory synapse assembly
+is_a: GO:0051965 {is_inferred="true"} ! positive regulation of synapse assembly
+is_a: GO:1905702 {is_inferred="true"} ! regulation of inhibitory synapse assembly
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37023 | termgenie | 2016-11-15 08:59:45 -0800 (Tue, 15 Nov 2016) | 4 lines

TermGenie commit for user: sl reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37023)
+++ go_inferences.obo	(working copy)
@@ -90897,6 +90897,37 @@
 is_a: GO:1905693 {is_inferred="true"} ! regulation of phosphatidic acid biosynthetic process
 
 [Term]
+id: GO:1905696 ! regulation of polysome binding
+is_a: GO:0051098 {is_inferred="true"} ! regulation of binding
+
+[Term]
+id: GO:1905697 ! negative regulation of polysome binding
+is_a: GO:0051100 {is_inferred="true"} ! negative regulation of binding
+is_a: GO:1905696 {is_inferred="true"} ! regulation of polysome binding
+
+[Term]
+id: GO:1905698 ! positive regulation of polysome binding
+is_a: GO:0051099 {is_inferred="true"} ! positive regulation of binding
+is_a: GO:1905696 {is_inferred="true"} ! regulation of polysome binding
+
+[Term]
+id: GO:1905699 ! regulation of drug transmembrane export
+is_a: GO:0034762 {is_inferred="true"} ! regulation of transmembrane transport
+is_a: GO:2001023 {is_inferred="true"} ! regulation of response to drug
+
+[Term]
+id: GO:1905700 ! negative regulation of drug transmembrane export
+is_a: GO:0034763 {is_inferred="true"} ! negative regulation of transmembrane transport
+is_a: GO:1905699 {is_inferred="true"} ! regulation of drug transmembrane export
+is_a: GO:2001024 {is_inferred="true"} ! negative regulation of response to drug
+
+[Term]
+id: GO:1905701 ! positive regulation of drug transmembrane export
+is_a: GO:0034764 {is_inferred="true"} ! positive regulation of transmembrane transport
+is_a: GO:1905699 {is_inferred="true"} ! regulation of drug transmembrane export
+is_a: GO:2001025 {is_inferred="true"} ! positive regulation of response to drug
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37016 | paola | 2016-11-15 01:27:56 -0800 (Tue, 15 Nov 2016) | 3 lines

GH OTR: add has_part links between autophagy and organelle disassembly #12754 - closed - see ticket for details

changes in entailments

------------------------------------------------------------------------
r37012 | termgenie | 2016-11-14 08:38:41 -0800 (Mon, 14 Nov 2016) | 4 lines

TermGenie commit for user: bc reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37012)
+++ go_inferences.obo	(working copy)
@@ -90880,6 +90880,23 @@
 is_a: GO:1903008 {is_inferred="true"} ! organelle disassembly
 
 [Term]
+id: GO:1905693 ! regulation of phosphatidic acid biosynthetic process
+is_a: GO:0009889 {is_inferred="true"} ! regulation of biosynthetic process
+is_a: GO:0051174 {is_inferred="true"} ! regulation of phosphorus metabolic process
+
+[Term]
+id: GO:1905694 ! negative regulation of phosphatidic acid biosynthetic process
+is_a: GO:0009890 {is_inferred="true"} ! negative regulation of biosynthetic process
+is_a: GO:0010563 {is_inferred="true"} ! negative regulation of phosphorus metabolic process
+is_a: GO:1905693 {is_inferred="true"} ! regulation of phosphatidic acid biosynthetic process
+
+[Term]
+id: GO:1905695 ! positive regulation of phosphatidic acid biosynthetic process
+is_a: GO:0009891 {is_inferred="true"} ! positive regulation of biosynthetic process
+is_a: GO:0010562 {is_inferred="true"} ! positive regulation of phosphorus metabolic process
+is_a: GO:1905693 {is_inferred="true"} ! regulation of phosphatidic acid biosynthetic process
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37010 | mcourtot | 2016-11-14 07:48:16 -0800 (Mon, 14 Nov 2016) | 1 line

added DNA geometric change' as parent to 'DNA strand renaturation'  as per https://github.com/geneontology/go-ontology/issues/12539

changes in entailments

------------------------------------------------------------------------
r37008 | termgenie | 2016-11-14 05:42:14 -0800 (Mon, 14 Nov 2016) | 4 lines

TermGenie commit for user: pr reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 37008)
+++ go_inferences.obo	(working copy)
@@ -90865,6 +90865,21 @@
 is_a: GO:1905687 {is_inferred="true"} ! regulation of diacylglycerol kinase activity
 
 [Term]
+id: GO:1905690 ! nucleus disassembly
+is_a: GO:0006997 {is_inferred="true"} ! nucleus organization
+is_a: GO:1903008 {is_inferred="true"} ! organelle disassembly
+
+[Term]
+id: GO:1905691 ! lipid particle disassembly
+is_a: GO:0034389 {is_inferred="true"} ! lipid particle organization
+is_a: GO:1903008 {is_inferred="true"} ! organelle disassembly
+
+[Term]
+id: GO:1905692 ! endoplasmic reticulum disassembly
+is_a: GO:0007029 {is_inferred="true"} ! endoplasmic reticulum organization
+is_a: GO:1903008 {is_inferred="true"} ! organelle disassembly
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r37001 | paola | 2016-11-14 05:33:01 -0800 (Mon, 14 Nov 2016) | 2 lines

GH OTR: add has_part links between autophagy and organelle disassembly #12754 - work in progress - pexophagy terms

changes in entailments

------------------------------------------------------------------------
r36999 | termgenie | 2016-11-14 04:59:59 -0800 (Mon, 14 Nov 2016) | 4 lines

TermGenie commit for user: bc reviewed by dph

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36999)
+++ go_inferences.obo	(working copy)
@@ -90834,6 +90834,37 @@
 is_a: GO:1903008 {is_inferred="true"} ! organelle disassembly
 
 [Term]
+id: GO:1905684 ! regulation of plasma membrane repair
+is_a: GO:0061041 {is_inferred="true"} ! regulation of wound healing
+is_a: GO:1903729 {is_inferred="true"} ! regulation of plasma membrane organization
+
+[Term]
+id: GO:1905685 ! negative regulation of plasma membrane repair
+is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
+is_a: GO:0061045 {is_inferred="true"} ! negative regulation of wound healing
+is_a: GO:1905684 {is_inferred="true"} ! regulation of plasma membrane repair
+
+[Term]
+id: GO:1905686 ! positive regulation of plasma membrane repair
+is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
+is_a: GO:0090303 {is_inferred="true"} ! positive regulation of wound healing
+is_a: GO:1905684 {is_inferred="true"} ! regulation of plasma membrane repair
+
+[Term]
+id: GO:1905687 ! regulation of diacylglycerol kinase activity
+is_a: GO:0043549 {is_inferred="true"} ! regulation of kinase activity
+
+[Term]
+id: GO:1905688 ! negative regulation of diacylglycerol kinase activity
+is_a: GO:0033673 {is_inferred="true"} ! negative regulation of kinase activity
+is_a: GO:1905687 {is_inferred="true"} ! regulation of diacylglycerol kinase activity
+
+[Term]
+id: GO:1905689 ! positive regulation of diacylglycerol kinase activity
+is_a: GO:0033674 {is_inferred="true"} ! positive regulation of kinase activity
+is_a: GO:1905687 {is_inferred="true"} ! regulation of diacylglycerol kinase activity
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36996 | termgenie | 2016-11-14 02:13:17 -0800 (Mon, 14 Nov 2016) | 2 lines

TermGenie commit for user: pr reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36996)
+++ go_inferences.obo	(working copy)
@@ -90829,6 +90829,11 @@
 is_a: GO:1905680 {is_inferred="true"} ! regulation of innate immunity memory response
 
 [Term]
+id: GO:1905683 ! peroxisome disassembly
+is_a: GO:0007031 {is_inferred="true"} ! peroxisome organization
+is_a: GO:1903008 {is_inferred="true"} ! organelle disassembly
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36991 | dph | 2016-11-13 10:56:53 -0800 (Sun, 13 Nov 2016) | 2 lines

Made macroautophagy an autophagy that starts with autphagosome assembly and made autophagosome assembly start with ATG1/ULK1 kinase complex assembly.

changes in entailments

------------------------------------------------------------------------
r36978 | dph | 2016-11-12 05:33:10 -0800 (Sat, 12 Nov 2016) | 2 lines

Removed the has input relationships from the autophagosome assembly terms.

changes in entailments

------------------------------------------------------------------------
r36957 | tberardi | 2016-11-11 18:03:21 -0800 (Fri, 11 Nov 2016) | 3 lines

GH12610 NTR component term: heteroreceptor complex - closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36957)
+++ go_inferences.obo	(working copy)
@@ -8271,7 +8271,7 @@
 
 [Term]
 id: GO:0007072 ! positive regulation of transcription involved in exit from mitosis
-is_a: GO:0045897 {is_inferred="true"} ! positive regulation of transcription during mitosis
+is_a: GO:0045893 {is_inferred="true"} ! positive regulation of transcription, DNA-templated
 is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
@@ -38704,15 +38704,6 @@
 is_a: GO:1903508 {is_inferred="true"} ! positive regulation of nucleic acid-templated transcription
 
 [Term]
-id: GO:0045896 ! regulation of transcription during mitosis
-is_a: GO:0006355 {is_inferred="true"} ! regulation of transcription, DNA-templated
-
-[Term]
-id: GO:0045897 ! positive regulation of transcription during mitosis
-is_a: GO:0045893 {is_inferred="true"} ! positive regulation of transcription, DNA-templated
-is_a: GO:0045896 {is_inferred="true"} ! regulation of transcription during mitosis
-
-[Term]
 id: GO:0045898 ! regulation of RNA polymerase II transcriptional preinitiation complex assembly
 is_a: GO:0060260 {is_inferred="true"} ! regulation of transcription initiation from RNA polymerase II promoter
 
@@ -39230,39 +39221,6 @@
 is_a: GO:0046013 {is_inferred="true"} ! regulation of T cell homeostatic proliferation
 
 [Term]
-id: GO:0046017 ! regulation of transcription from RNA polymerase I promoter, mitotic
-is_a: GO:0006356 {is_inferred="true"} ! regulation of transcription from RNA polymerase I promoter
-is_a: GO:0045896 {is_inferred="true"} ! regulation of transcription during mitosis
-
-[Term]
-id: GO:0046018 ! positive regulation of transcription from RNA polymerase I promoter during mitosis
-is_a: GO:0045897 {is_inferred="true"} ! positive regulation of transcription during mitosis
-is_a: GO:0045943 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase I promoter
-is_a: GO:0046017 {is_inferred="true"} ! regulation of transcription from RNA polymerase I promoter, mitotic
-
-[Term]
-id: GO:0046021 ! regulation of transcription from RNA polymerase II promoter, mitotic
-is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
-is_a: GO:0045896 {is_inferred="true"} ! regulation of transcription during mitosis
-
-[Term]
-id: GO:0046022 ! positive regulation of transcription from RNA polymerase II promoter during mitosis
-is_a: GO:0045897 {is_inferred="true"} ! positive regulation of transcription during mitosis
-is_a: GO:0045944 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter
-is_a: GO:0046021 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter, mitotic
-
-[Term]
-id: GO:0046023 ! regulation of transcription from RNA polymerase III promoter, mitotic
-is_a: GO:0006359 {is_inferred="true"} ! regulation of transcription from RNA polymerase III promoter
-is_a: GO:0045896 {is_inferred="true"} ! regulation of transcription during mitosis
-
-[Term]
-id: GO:0046024 ! positive regulation of transcription from RNA polymerase III promoter during mitosis
-is_a: GO:0045897 {is_inferred="true"} ! positive regulation of transcription during mitosis
-is_a: GO:0045945 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase III promoter
-is_a: GO:0046023 {is_inferred="true"} ! regulation of transcription from RNA polymerase III promoter, mitotic
-
-[Term]
 id: GO:0046031 ! ADP metabolic process
 is_a: GO:0009150 {is_inferred="true"} ! purine ribonucleotide metabolic process
 is_a: GO:0009167 {is_inferred="true"} ! purine ribonucleoside monophosphate metabolic process
------------------------------------------------------------------------
r36954 | termgenie | 2016-11-11 14:30:00 -0800 (Fri, 11 Nov 2016) | 10 lines

TermGenie commit for user: tb reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36954)
+++ go_inferences.obo	(working copy)
@@ -90807,6 +90807,70 @@
 is_a: GO:1905666 {is_inferred="true"} ! regulation of protein localization to endosome
 
 [Term]
+id: GO:1905669 ! TORC1 complex assembly
+is_a: GO:0006461 {is_inferred="true"} ! protein complex assembly
+
+[Term]
+id: GO:1905670 ! TORC2 complex disassembly
+is_a: GO:0043241 {is_inferred="true"} ! protein complex disassembly
+
+[Term]
+id: GO:1905671 ! regulation of lysosome organization
+is_a: GO:0044088 {is_inferred="true"} ! regulation of vacuole organization
+
+[Term]
+id: GO:1905672 ! negative regulation of lysosome organization
+is_a: GO:0010639 {is_inferred="true"} ! negative regulation of organelle organization
+is_a: GO:1905671 {is_inferred="true"} ! regulation of lysosome organization
+
+[Term]
+id: GO:1905673 ! positive regulation of lysosome organization
+is_a: GO:0044090 {is_inferred="true"} ! positive regulation of vacuole organization
+is_a: GO:1905671 {is_inferred="true"} ! regulation of lysosome organization
+
+[Term]
+id: GO:1905674 ! regulation of adaptive immune memory response
+is_a: GO:0002819 {is_inferred="true"} ! regulation of adaptive immune response
+
+[Term]
+id: GO:1905675 ! negative regulation of adaptive immune memory response
+is_a: GO:0002820 {is_inferred="true"} ! negative regulation of adaptive immune response
+is_a: GO:1905674 {is_inferred="true"} ! regulation of adaptive immune memory response
+
+[Term]
+id: GO:1905676 ! positive regulation of adaptive immune memory response
+is_a: GO:0002821 {is_inferred="true"} ! positive regulation of adaptive immune response
+is_a: GO:1905674 {is_inferred="true"} ! regulation of adaptive immune memory response
+
+[Term]
+id: GO:1905677 ! regulation of adaptive immune effector response
+is_a: GO:0002819 {is_inferred="true"} ! regulation of adaptive immune response
+
+[Term]
+id: GO:1905678 ! negative regulation of adaptive immune effector response
+is_a: GO:0002820 {is_inferred="true"} ! negative regulation of adaptive immune response
+is_a: GO:1905677 {is_inferred="true"} ! regulation of adaptive immune effector response
+
+[Term]
+id: GO:1905679 ! positive regulation of adaptive immune effector response
+is_a: GO:0002821 {is_inferred="true"} ! positive regulation of adaptive immune response
+is_a: GO:1905677 {is_inferred="true"} ! regulation of adaptive immune effector response
+
+[Term]
+id: GO:1905680 ! regulation of innate immunity memory response
+is_a: GO:0045088 {is_inferred="true"} ! regulation of innate immune response
+
+[Term]
+id: GO:1905681 ! negative regulation of innate immunity memory response
+is_a: GO:0045824 {is_inferred="true"} ! negative regulation of innate immune response
+is_a: GO:1905680 {is_inferred="true"} ! regulation of innate immunity memory response
+
+[Term]
+id: GO:1905682 ! positive regulation of innate immunity memory response
+is_a: GO:0045089 {is_inferred="true"} ! positive regulation of innate immune response
+is_a: GO:1905680 {is_inferred="true"} ! regulation of innate immunity memory response
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36950 | tberardi | 2016-11-11 12:49:23 -0800 (Fri, 11 Nov 2016) | 1 line

GH12671 adaptive immune response - added third set of new terms

changes in entailments

------------------------------------------------------------------------
r36948 | tberardi | 2016-11-11 12:42:57 -0800 (Fri, 11 Nov 2016) | 1 line

GH12671 adaptive immune response - added second set of new terms

changes in entailments

------------------------------------------------------------------------
r36946 | tberardi | 2016-11-11 12:31:39 -0800 (Fri, 11 Nov 2016) | 1 line

GH12671 adaptive immune response - added new terms related to memory

changes in entailments

------------------------------------------------------------------------
r36944 | tberardi | 2016-11-11 12:19:21 -0800 (Fri, 11 Nov 2016) | 1 line

GH12671 adaptive immune response - modified definitions

changes in entailments

------------------------------------------------------------------------
r36940 | dph | 2016-11-11 11:01:00 -0800 (Fri, 11 Nov 2016) | 2 lines

GH12792-closed

changes in entailments

------------------------------------------------------------------------
r36938 | dph | 2016-11-11 10:47:18 -0800 (Fri, 11 Nov 2016) | 2 lines

GH12784-closed

changes in entailments

------------------------------------------------------------------------
r36932 | mcourtot | 2016-11-11 05:22:36 -0800 (Fri, 11 Nov 2016) | 1 line

added tRNA-guanine transglycosylation and taxon restriction on GO:0008616 queuosine biosynthetic process as per https://github.com/geneontology/go-ontology/issues/12536

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36932)
+++ go_inferences.obo	(working copy)
@@ -77662,12 +77662,12 @@
 
 [Term]
 id: GO:1902965 ! regulation of protein localization to early endosome
-is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
+is_a: GO:1905666 {is_inferred="true"} ! regulation of protein localization to endosome
 
 [Term]
 id: GO:1902966 ! positive regulation of protein localization to early endosome
 is_a: GO:1902965 {is_inferred="true"} ! regulation of protein localization to early endosome
-is_a: GO:1903829 {is_inferred="true"} ! positive regulation of cellular protein localization
+is_a: GO:1905668 {is_inferred="true"} ! positive regulation of protein localization to endosome
 
 [Term]
 id: GO:1902967 ! protein localization to mitotic spindle midzone
@@ -90780,6 +90780,33 @@
 is_a: GO:1905661 {is_inferred="true"} ! regulation of telomerase RNA reverse transcriptase activity
 
 [Term]
+id: GO:1905664 ! regulation of calcium ion import across plasma membrane
+is_a: GO:0010522 {is_inferred="true"} ! regulation of calcium ion transport into cytosol
+is_a: GO:0090279 {is_inferred="true"} ! regulation of calcium ion import
+is_a: GO:1903169 {is_inferred="true"} ! regulation of calcium ion transmembrane transport
+
+[Term]
+id: GO:1905665 ! positive regulation of calcium ion import across plasma membrane
+is_a: GO:0010524 {is_inferred="true"} ! positive regulation of calcium ion transport into cytosol
+is_a: GO:0090280 {is_inferred="true"} ! positive regulation of calcium ion import
+is_a: GO:1904427 {is_inferred="true"} ! positive regulation of calcium ion transmembrane transport
+is_a: GO:1905664 {is_inferred="true"} ! regulation of calcium ion import across plasma membrane
+
+[Term]
+id: GO:1905666 ! regulation of protein localization to endosome
+is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
+
+[Term]
+id: GO:1905667 ! negative regulation of protein localization to endosome
+is_a: GO:1903828 {is_inferred="true"} ! negative regulation of cellular protein localization
+is_a: GO:1905666 {is_inferred="true"} ! regulation of protein localization to endosome
+
+[Term]
+id: GO:1905668 ! positive regulation of protein localization to endosome
+is_a: GO:1903829 {is_inferred="true"} ! positive regulation of cellular protein localization
+is_a: GO:1905666 {is_inferred="true"} ! regulation of protein localization to endosome
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36927 | dph | 2016-11-11 04:57:37 -0800 (Fri, 11 Nov 2016) | 2 lines

Trying to remove logical error of multiply labeled edge on GO:0061804.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36927)
+++ go_inferences.obo	(working copy)
@@ -51189,7 +51189,8 @@
 
 [Term]
 id: GO:0061804 ! mitotic spindle elongation during mitotic prophase
-is_a: GO:0000022 {is_inferred="true"} ! mitotic spindle elongation
+is_a: GO:0007052 {is_inferred="true"} ! mitotic spindle organization
+is_a: GO:1902850 {is_inferred="true"} ! microtubule cytoskeleton organization involved in mitosis
 
 [Term]
 id: GO:0061805 ! mitotic spindle elongation during mitotic anaphase
------------------------------------------------------------------------
r36924 | dph | 2016-11-10 12:30:49 -0800 (Thu, 10 Nov 2016) | 2 lines

GH12791-closed.

changes in entailments

------------------------------------------------------------------------
r36916 | termgenie | 2016-11-10 06:09:52 -0800 (Thu, 10 Nov 2016) | 4 lines

TermGenie commit for user: rph reviewed by dph

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36916)
+++ go_inferences.obo	(working copy)
@@ -81904,18 +81904,17 @@
 
 [Term]
 id: GO:1903847 ! regulation of aorta morphogenesis
-is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
-is_a: GO:1901342 {is_inferred="true"} ! regulation of vasculature development
+is_a: GO:1905651 {is_inferred="true"} ! regulation of artery morphogenesis
 
 [Term]
 id: GO:1903848 ! negative regulation of aorta morphogenesis
 is_a: GO:1903847 {is_inferred="true"} ! regulation of aorta morphogenesis
-is_a: GO:2000181 {is_inferred="true"} ! negative regulation of blood vessel morphogenesis
+is_a: GO:1905652 {is_inferred="true"} ! negative regulation of artery morphogenesis
 
 [Term]
 id: GO:1903849 ! positive regulation of aorta morphogenesis
 is_a: GO:1903847 {is_inferred="true"} ! regulation of aorta morphogenesis
-is_a: GO:1904018 {is_inferred="true"} ! positive regulation of vasculature development
+is_a: GO:1905653 {is_inferred="true"} ! positive regulation of artery morphogenesis
 
 [Term]
 id: GO:1903850 ! regulation of cristae formation
@@ -84314,18 +84313,17 @@
 
 [Term]
 id: GO:1904335 ! regulation of ductus arteriosus closure
-is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
-is_a: GO:1901342 {is_inferred="true"} ! regulation of vasculature development
+is_a: GO:1905651 {is_inferred="true"} ! regulation of artery morphogenesis
 
 [Term]
 id: GO:1904336 ! negative regulation of ductus arteriosus closure
 is_a: GO:1904335 {is_inferred="true"} ! regulation of ductus arteriosus closure
-is_a: GO:2000181 {is_inferred="true"} ! negative regulation of blood vessel morphogenesis
+is_a: GO:1905652 {is_inferred="true"} ! negative regulation of artery morphogenesis
 
 [Term]
 id: GO:1904337 ! positive regulation of ductus arteriosus closure
-is_a: GO:1904018 {is_inferred="true"} ! positive regulation of vasculature development
 is_a: GO:1904335 {is_inferred="true"} ! regulation of ductus arteriosus closure
+is_a: GO:1905653 {is_inferred="true"} ! positive regulation of artery morphogenesis
 
 [Term]
 id: GO:1904338 ! regulation of dopaminergic neuron differentiation
@@ -90715,6 +90713,21 @@
 is_a: GO:1905648 {is_inferred="true"} ! regulation of shell calcification
 
 [Term]
+id: GO:1905651 ! regulation of artery morphogenesis
+is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
+is_a: GO:1901342 {is_inferred="true"} ! regulation of vasculature development
+
+[Term]
+id: GO:1905652 ! negative regulation of artery morphogenesis
+is_a: GO:1905651 {is_inferred="true"} ! regulation of artery morphogenesis
+is_a: GO:2000181 {is_inferred="true"} ! negative regulation of blood vessel morphogenesis
+
+[Term]
+id: GO:1905653 ! positive regulation of artery morphogenesis
+is_a: GO:1904018 {is_inferred="true"} ! positive regulation of vasculature development
+is_a: GO:1905651 {is_inferred="true"} ! regulation of artery morphogenesis
+
+[Term]
 id: GO:1905654 ! regulation of artery smooth muscle contraction
 is_a: GO:0003056 {is_inferred="true"} ! regulation of vascular smooth muscle contraction
 
------------------------------------------------------------------------
r36914 | termgenie | 2016-11-10 05:39:28 -0800 (Thu, 10 Nov 2016) | 4 lines

TermGenie commit for user: nc reviewed by dph

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36914)
+++ go_inferences.obo	(working copy)
@@ -83969,10 +83969,9 @@
 
 [Term]
 id: GO:1904271 ! L-proline import across plasma membrane
-is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
-is_a: GO:1902825 {is_inferred="true"} ! proline import into cell
 is_a: GO:1903809 {is_inferred="true"} ! L-proline import into cell
 is_a: GO:1904555 {is_inferred="true"} ! L-proline transmembrane transport
+is_a: GO:1905647 {is_inferred="true"} ! proline import across plasma membrane
 
 [Term]
 id: GO:1904272 ! L-tryptophan import across plasma membrane
@@ -90682,6 +90681,91 @@
 is_a: GO:0051054 {is_inferred="true"} ! positive regulation of DNA metabolic process
 
 [Term]
+id: GO:1905644 ! regulation of FACT complex assembly
+is_a: GO:0043254 {is_inferred="true"} ! regulation of protein complex assembly
+
+[Term]
+id: GO:1905645 ! negative regulation of FACT complex assembly
+is_a: GO:0031333 {is_inferred="true"} ! negative regulation of protein complex assembly
+is_a: GO:1905644 {is_inferred="true"} ! regulation of FACT complex assembly
+
+[Term]
+id: GO:1905646 ! positive regulation of FACT complex assembly
+is_a: GO:0031334 {is_inferred="true"} ! positive regulation of protein complex assembly
+is_a: GO:1905644 {is_inferred="true"} ! regulation of FACT complex assembly
+
+[Term]
+id: GO:1905647 ! proline import across plasma membrane
+is_a: GO:0035524 {is_inferred="true"} ! proline transmembrane transport
+is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
+is_a: GO:1902825 {is_inferred="true"} ! proline import into cell
+
+[Term]
+id: GO:1905648 ! regulation of shell calcification
+is_a: GO:0070167 {is_inferred="true"} ! regulation of biomineral tissue development
+
+[Term]
+id: GO:1905649 ! negative regulation of shell calcification
+is_a: GO:0070168 {is_inferred="true"} ! negative regulation of biomineral tissue development
+is_a: GO:1905648 {is_inferred="true"} ! regulation of shell calcification
+
+[Term]
+id: GO:1905650 ! positive regulation of shell calcification
+is_a: GO:0070169 {is_inferred="true"} ! positive regulation of biomineral tissue development
+is_a: GO:1905648 {is_inferred="true"} ! regulation of shell calcification
+
+[Term]
+id: GO:1905654 ! regulation of artery smooth muscle contraction
+is_a: GO:0003056 {is_inferred="true"} ! regulation of vascular smooth muscle contraction
+
+[Term]
+id: GO:1905655 ! negative regulation of artery smooth muscle contraction
+is_a: GO:1904694 {is_inferred="true"} ! negative regulation of vascular smooth muscle contraction
+is_a: GO:1905654 {is_inferred="true"} ! regulation of artery smooth muscle contraction
+
+[Term]
+id: GO:1905656 ! positive regulation of artery smooth muscle contraction
+is_a: GO:1904695 {is_inferred="true"} ! positive regulation of vascular smooth muscle contraction
+is_a: GO:1905654 {is_inferred="true"} ! regulation of artery smooth muscle contraction
+
+[Term]
+id: GO:1905657 ! regulation of relaxation of vascular smooth muscle
+is_a: GO:0006940 {is_inferred="true"} ! regulation of smooth muscle contraction
+is_a: GO:0042312 {is_inferred="true"} ! regulation of vasodilation
+is_a: GO:1901080 {is_inferred="true"} ! regulation of relaxation of smooth muscle
+
+[Term]
+id: GO:1905658 ! negative regulation of relaxation of vascular smooth muscle
+is_a: GO:0045908 {is_inferred="true"} ! negative regulation of vasodilation
+is_a: GO:0045987 {is_inferred="true"} ! positive regulation of smooth muscle contraction
+is_a: GO:1901081 {is_inferred="true"} ! negative regulation of relaxation of smooth muscle
+is_a: GO:1905657 {is_inferred="true"} ! regulation of relaxation of vascular smooth muscle
+
+[Term]
+id: GO:1905659 ! positive regulation of relaxation of vascular smooth muscle
+is_a: GO:0045909 {is_inferred="true"} ! positive regulation of vasodilation
+is_a: GO:1901082 {is_inferred="true"} ! positive regulation of relaxation of smooth muscle
+is_a: GO:1905657 {is_inferred="true"} ! regulation of relaxation of vascular smooth muscle
+
+[Term]
+id: GO:1905660 ! mitotic checkpoint complex assembly
+is_a: GO:0006461 {is_inferred="true"} ! protein complex assembly
+
+[Term]
+id: GO:1905661 ! regulation of telomerase RNA reverse transcriptase activity
+is_a: GO:0051972 {is_inferred="true"} ! regulation of telomerase activity
+
+[Term]
+id: GO:1905662 ! negative regulation of telomerase RNA reverse transcriptase activity
+is_a: GO:0051974 {is_inferred="true"} ! negative regulation of telomerase activity
+is_a: GO:1905661 {is_inferred="true"} ! regulation of telomerase RNA reverse transcriptase activity
+
+[Term]
+id: GO:1905663 ! positive regulation of telomerase RNA reverse transcriptase activity
+is_a: GO:0051973 {is_inferred="true"} ! positive regulation of telomerase activity
+is_a: GO:1905661 {is_inferred="true"} ! regulation of telomerase RNA reverse transcriptase activity
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36904 | mcourtot | 2016-11-09 08:20:11 -0800 (Wed, 09 Nov 2016) | 1 line

removed offending consider tag

changes in entailments

------------------------------------------------------------------------
r36901 | mcourtot | 2016-11-09 07:57:05 -0800 (Wed, 09 Nov 2016) | 1 line

deprecated GO:0050983 deoxyhypusine biosynthetic process from spermidine as per https://github.com/geneontology/go-ontology/issues/12723

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36901)
+++ go_inferences.obo	(working copy)
@@ -44586,13 +44586,6 @@
 is_a: GO:0050962 {is_inferred="true"} ! detection of light stimulus involved in sensory perception
 
 [Term]
-id: GO:0050983 ! deoxyhypusine biosynthetic process from spermidine
-is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
-is_a: GO:0042398 {is_inferred="true"} ! cellular modified amino acid biosynthetic process
-is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
-is_a: GO:1901607 {is_inferred="true"} ! alpha-amino acid biosynthetic process
-
-[Term]
 id: GO:0050992 ! dimethylallyl diphosphate biosynthetic process
 is_a: GO:0008654 {is_inferred="true"} ! phospholipid biosynthetic process
 is_a: GO:0050993 {is_inferred="true"} ! dimethylallyl diphosphate metabolic process
------------------------------------------------------------------------
r36898 | paola | 2016-11-09 03:54:16 -0800 (Wed, 09 Nov 2016) | 2 lines

GH Cellular component assembly/disassembly - add missing logical definitions #12232 - work in progress - renamed and redefined ‘NMS complex assembly involved in kinetochore assembly’ regulation terms, and added link to 'NMS complex'

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36899)
+++ go_inferences.obo	(working copy)
@@ -71546,13 +71546,13 @@
 is_a: GO:2001148 {is_inferred="true"} ! regulation of dipeptide transmembrane transport
 
 [Term]
-id: GO:1901720 ! negative regulation of NMS complex assembly involved in kinetochore assembly
-is_a: GO:1901719 {is_inferred="true"} ! regulation of NMS complex assembly involved in kinetochore assembly
+id: GO:1901720 ! negative regulation of NMS complex assembly
+is_a: GO:1901719 {is_inferred="true"} ! regulation of NMS complex assembly
 is_a: GO:1905560 {is_inferred="true"} ! negative regulation of kinetochore assembly
 
 [Term]
-id: GO:1901721 ! positive regulation of NMS complex assembly involved in kinetochore assembly
-is_a: GO:1901719 {is_inferred="true"} ! regulation of NMS complex assembly involved in kinetochore assembly
+id: GO:1901721 ! positive regulation of NMS complex assembly
+is_a: GO:1901719 {is_inferred="true"} ! regulation of NMS complex assembly
 is_a: GO:1905561 {is_inferred="true"} ! positive regulation of kinetochore assembly
 
 [Term]
------------------------------------------------------------------------
r36897 | paola | 2016-11-09 03:46:18 -0800 (Wed, 09 Nov 2016) | 2 lines

GH Cellular component assembly/disassembly - add missing logical definitions #12232 - work in progress - renamed and redefined ‘NMS complex assembly involved in kinetochore assembly’

changes in entailments

------------------------------------------------------------------------
r36892 | paola | 2016-11-09 02:27:37 -0800 (Wed, 09 Nov 2016) | 3 lines

GH GO:0043936 asexual sporulation resulting in the formation of a cellular spore #12744 - closed - added synonym to 'asexual sporulation'

changes in entailments

------------------------------------------------------------------------
r36885 | paola | 2016-11-08 01:57:28 -0800 (Tue, 08 Nov 2016) | 3 lines

GH NTR: tRNA 5'-end processing / children of RNA repair? / 3′-5′ RNA polymerase activity #12756 - work in progress - added GO:0097745 mitochondrial tRNA 5'-end processing

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36885)
+++ go_inferences.obo	(working copy)
@@ -60351,6 +60351,10 @@
 is_a: GO:0044441 {is_inferred="true"} ! ciliary part
 
 [Term]
+id: GO:0097745 ! mitochondrial tRNA 5'-end processing
+is_a: GO:0034471 {is_inferred="true"} ! ncRNA 5'-end processing
+
+[Term]
 id: GO:0098003 ! viral tail assembly
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
 
------------------------------------------------------------------------
r36883 | paola | 2016-11-08 00:52:15 -0800 (Tue, 08 Nov 2016) | 3 lines

GH OTR: GO:0045005 (DNA-dependent DNA replication maintenance of fidelity) #12749 - closed - added def. gloss to ‘replication fork arrest’

changes in entailments

------------------------------------------------------------------------
r36878 | dph | 2016-11-07 08:24:07 -0800 (Mon, 07 Nov 2016) | 2 lines

Added relation to deactivation of mitotic spindle assembly checkpoint.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36878)
+++ go_inferences.obo	(working copy)
@@ -75103,6 +75103,14 @@
 is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
 
 [Term]
+id: GO:1902426 ! deactivation of mitotic spindle assembly checkpoint
+is_a: GO:0010948 {is_inferred="true"} ! negative regulation of cell cycle process
+is_a: GO:0045842 {is_inferred="true"} ! positive regulation of mitotic metaphase/anaphase transition
+is_a: GO:0045930 {is_inferred="true"} ! negative regulation of mitotic cell cycle
+is_a: GO:0090233 {is_inferred="true"} ! negative regulation of spindle checkpoint
+is_a: GO:0090266 {is_inferred="true"} ! regulation of mitotic cell cycle spindle assembly checkpoint
+
+[Term]
 id: GO:1902427 ! regulation of water channel activity
 is_a: GO:0022898 {is_inferred="true"} ! regulation of transmembrane transporter activity
 
------------------------------------------------------------------------
r36871 | dph | 2016-11-06 20:30:53 -0800 (Sun, 06 Nov 2016) | 2 lines

GH12642-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36871)
+++ go_inferences.obo	(working copy)
@@ -16877,10 +16877,6 @@
 is_a: GO:0016241 {is_inferred="true"} ! regulation of macroautophagy
 
 [Term]
-id: GO:0016240 ! autophagosome docking
-is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
-
-[Term]
 id: GO:0016241 ! regulation of macroautophagy
 is_a: GO:0010506 {is_inferred="true"} ! regulation of autophagy
 
------------------------------------------------------------------------
r36869 | dph | 2016-11-06 20:19:21 -0800 (Sun, 06 Nov 2016) | 2 lines

GH12431-closed. Made changes that weren't saved in earlier edits.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36869)
+++ go_inferences.obo	(working copy)
@@ -425,6 +425,8 @@
 
 [Term]
 id: GO:0000212 ! meiotic spindle organization
+is_a: GO:0007051 {is_inferred="true"} ! spindle organization
+is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
@@ -8227,6 +8229,7 @@
 
 [Term]
 id: GO:0007052 ! mitotic spindle organization
+is_a: GO:0007051 {is_inferred="true"} ! spindle organization
 is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
@@ -45263,14 +45266,13 @@
 
 [Term]
 id: GO:0051228 ! mitotic spindle disassembly
+is_a: GO:0007052 {is_inferred="true"} ! mitotic spindle organization
 is_a: GO:0051230 {is_inferred="true"} ! spindle disassembly
-is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
 id: GO:0051229 ! meiotic spindle disassembly
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0000212 {is_inferred="true"} ! meiotic spindle organization
 is_a: GO:0051230 {is_inferred="true"} ! spindle disassembly
-is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
 id: GO:0051230 ! spindle disassembly
@@ -48008,7 +48010,7 @@
 [Term]
 id: GO:0060236 ! regulation of mitotic spindle organization
 is_a: GO:0007346 {is_inferred="true"} ! regulation of mitotic cell cycle
-is_a: GO:0010564 {is_inferred="true"} ! regulation of cell cycle process
+is_a: GO:0090224 {is_inferred="true"} ! regulation of spindle organization
 
 [Term]
 id: GO:0060237 ! regulation of fungal-type cell wall organization
@@ -51197,6 +51199,15 @@
 is_a: GO:0005254 {is_inferred="true"} ! chloride channel activity
 
 [Term]
+id: GO:0061804 ! mitotic spindle elongation during mitotic prophase
+is_a: GO:0000022 {is_inferred="true"} ! mitotic spindle elongation
+
+[Term]
+id: GO:0061805 ! mitotic spindle elongation during mitotic anaphase
+is_a: GO:0007052 {is_inferred="true"} ! mitotic spindle organization
+is_a: GO:1902850 {is_inferred="true"} ! microtubule cytoskeleton organization involved in mitosis
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
@@ -59044,12 +59055,12 @@
 
 [Term]
 id: GO:0090306 ! spindle assembly involved in meiosis
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0000212 {is_inferred="true"} ! meiotic spindle organization
 is_a: GO:0051225 {is_inferred="true"} ! spindle assembly
-is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
 id: GO:0090307 ! mitotic spindle assembly
+is_a: GO:0007052 {is_inferred="true"} ! mitotic spindle organization
 is_a: GO:0051225 {is_inferred="true"} ! spindle assembly
 is_a: GO:1902850 {is_inferred="true"} ! microtubule cytoskeleton organization involved in mitosis
 
@@ -71313,6 +71324,7 @@
 [Term]
 id: GO:1901673 ! regulation of mitotic spindle assembly
 is_a: GO:0007088 {is_inferred="true"} ! regulation of mitotic nuclear division
+is_a: GO:0060236 {is_inferred="true"} ! regulation of mitotic spindle organization
 is_a: GO:0090169 {is_inferred="true"} ! regulation of spindle assembly
 
 [Term]
@@ -86021,8 +86033,7 @@
 
 [Term]
 id: GO:1904686 ! regulation of mitotic spindle disassembly
-is_a: GO:0007346 {is_inferred="true"} ! regulation of mitotic cell cycle
-is_a: GO:0090224 {is_inferred="true"} ! regulation of spindle organization
+is_a: GO:0060236 {is_inferred="true"} ! regulation of mitotic spindle organization
 
 [Term]
 id: GO:1904687 ! positive regulation of mitotic spindle disassembly
------------------------------------------------------------------------
r36867 | dph | 2016-11-06 19:58:37 -0800 (Sun, 06 Nov 2016) | 2 lines

GH12781-closed

changes in entailments

------------------------------------------------------------------------
r36861 | dph | 2016-11-06 16:07:27 -0800 (Sun, 06 Nov 2016) | 2 lines

GH12366-closed. Fixed up the cell cycle checkpoints.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36861)
+++ go_inferences.obo	(working copy)
@@ -56115,12 +56115,10 @@
 
 [Term]
 id: GO:0072421 ! detection of DNA damage stimulus involved in DNA damage checkpoint
-is_a: GO:0022402 {is_inferred="true"} ! cell cycle process
 is_a: GO:0042769 {is_inferred="true"} ! DNA damage response, detection of DNA damage
 
 [Term]
 id: GO:0072422 ! signal transduction involved in DNA damage checkpoint
-is_a: GO:0022402 {is_inferred="true"} ! cell cycle process
 is_a: GO:0072401 {is_inferred="true"} ! signal transduction involved in DNA integrity checkpoint
 
 [Term]
@@ -56164,10 +56162,6 @@
 is_a: GO:1902402 {is_inferred="true"} ! signal transduction involved in mitotic DNA damage checkpoint
 
 [Term]
-id: GO:0072436 ! detection of stimulus involved in DNA replication checkpoint
-is_a: GO:0022402 {is_inferred="true"} ! cell cycle process
-
-[Term]
 id: GO:0072437 ! signal transduction involved in DNA replication checkpoint
 is_a: GO:0072401 {is_inferred="true"} ! signal transduction involved in DNA integrity checkpoint
 
@@ -58889,6 +58883,7 @@
 [Term]
 id: GO:0090267 ! positive regulation of mitotic cell cycle spindle assembly checkpoint
 is_a: GO:0045931 {is_inferred="true"} ! positive regulation of mitotic cell cycle
+is_a: GO:0090068 {is_inferred="true"} ! positive regulation of cell cycle process
 is_a: GO:0090232 {is_inferred="true"} ! positive regulation of spindle checkpoint
 is_a: GO:0090266 {is_inferred="true"} ! regulation of mitotic cell cycle spindle assembly checkpoint
 
@@ -72892,16 +72887,17 @@
 
 [Term]
 id: GO:1901976 ! regulation of cell cycle checkpoint
-is_a: GO:0010564 {is_inferred="true"} ! regulation of cell cycle process
+is_a: GO:0051726 {is_inferred="true"} ! regulation of cell cycle
 
 [Term]
 id: GO:1901977 ! negative regulation of cell cycle checkpoint
-is_a: GO:0010948 {is_inferred="true"} ! negative regulation of cell cycle process
+is_a: GO:0045787 {is_inferred="true"} ! positive regulation of cell cycle
+is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
 is_a: GO:1901976 {is_inferred="true"} ! regulation of cell cycle checkpoint
 
 [Term]
 id: GO:1901978 ! positive regulation of cell cycle checkpoint
-is_a: GO:0090068 {is_inferred="true"} ! positive regulation of cell cycle process
+is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
 is_a: GO:1901976 {is_inferred="true"} ! regulation of cell cycle checkpoint
 
 [Term]
@@ -75099,13 +75095,6 @@
 is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
 
 [Term]
-id: GO:1902426 ! deactivation of mitotic spindle assembly checkpoint
-is_a: GO:0045842 {is_inferred="true"} ! positive regulation of mitotic metaphase/anaphase transition
-is_a: GO:0045930 {is_inferred="true"} ! negative regulation of mitotic cell cycle
-is_a: GO:0090233 {is_inferred="true"} ! negative regulation of spindle checkpoint
-is_a: GO:0090266 {is_inferred="true"} ! regulation of mitotic cell cycle spindle assembly checkpoint
-
-[Term]
 id: GO:1902427 ! regulation of water channel activity
 is_a: GO:0022898 {is_inferred="true"} ! regulation of transmembrane transporter activity
 
@@ -84055,10 +84044,12 @@
 [Term]
 id: GO:1904289 ! regulation of mitotic DNA damage checkpoint
 is_a: GO:0007346 {is_inferred="true"} ! regulation of mitotic cell cycle
+is_a: GO:0010564 {is_inferred="true"} ! regulation of cell cycle process
 is_a: GO:2000001 {is_inferred="true"} ! regulation of DNA damage checkpoint
 
 [Term]
 id: GO:1904290 ! negative regulation of mitotic DNA damage checkpoint
+is_a: GO:0010948 {is_inferred="true"} ! negative regulation of cell cycle process
 is_a: GO:0045930 {is_inferred="true"} ! negative regulation of mitotic cell cycle
 is_a: GO:0045931 {is_inferred="true"} ! positive regulation of mitotic cell cycle
 is_a: GO:1904289 {is_inferred="true"} ! regulation of mitotic DNA damage checkpoint
@@ -84067,6 +84058,7 @@
 [Term]
 id: GO:1904291 ! positive regulation of mitotic DNA damage checkpoint
 is_a: GO:0045931 {is_inferred="true"} ! positive regulation of mitotic cell cycle
+is_a: GO:0090068 {is_inferred="true"} ! positive regulation of cell cycle process
 is_a: GO:1904289 {is_inferred="true"} ! regulation of mitotic DNA damage checkpoint
 is_a: GO:2000003 {is_inferred="true"} ! positive regulation of DNA damage checkpoint
 
@@ -89915,7 +89907,6 @@
 
 [Term]
 id: GO:1905482 ! cytoplasmic sequestering of protein involved in G2 DNA damage checkpoint
-is_a: GO:0022402 {is_inferred="true"} ! cell cycle process
 is_a: GO:0051220 {is_inferred="true"} ! cytoplasmic sequestering of protein
 
 [Term]
------------------------------------------------------------------------
r36853 | termgenie | 2016-11-06 06:07:02 -0800 (Sun, 06 Nov 2016) | 3 lines

TermGenie commit for user: bc reviewed by dos

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36857)
+++ go_inferences.obo	(working copy)
@@ -90633,6 +90633,10 @@
 is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
 
 [Term]
+id: GO:1905635 ! FACT complex assembly
+is_a: GO:0006461 {is_inferred="true"} ! protein complex assembly
+
+[Term]
 id: GO:1905636 ! positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding
 is_a: GO:1903025 {is_inferred="true"} ! regulation of RNA polymerase II regulatory region sequence-specific DNA binding
 is_a: GO:2000679 {is_inferred="true"} ! positive regulation of transcription regulatory region DNA binding
@@ -90655,6 +90659,26 @@
 is_a: GO:1905637 {is_inferred="true"} ! regulation of mitochondrial mRNA catabolic process
 
 [Term]
+id: GO:1905640 ! response to acetaldehyde
+is_a: GO:0010033 {is_inferred="true"} ! response to organic substance
+is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
+
+[Term]
+id: GO:1905641 ! cellular response to acetaldehyde
+is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
+is_a: GO:1905640 {is_inferred="true"} ! response to acetaldehyde
+
+[Term]
+id: GO:1905642 ! negative regulation of DNA methylation
+is_a: GO:0044030 {is_inferred="true"} ! regulation of DNA methylation
+is_a: GO:0051053 {is_inferred="true"} ! negative regulation of DNA metabolic process
+
+[Term]
+id: GO:1905643 ! positive regulation of DNA methylation
+is_a: GO:0044030 {is_inferred="true"} ! regulation of DNA methylation
+is_a: GO:0051054 {is_inferred="true"} ! positive regulation of DNA metabolic process
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36796 | termgenie | 2016-11-03 13:27:39 -0700 (Thu, 03 Nov 2016) | 4 lines

TermGenie commit for user: tb reviewed by tb

changes in entailments

------------------------------------------------------------------------
r36796 | termgenie | 2016-11-03 13:27:39 -0700 (Thu, 03 Nov 2016) | 4 lines

TermGenie commit for user: tb reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36796)
+++ go_inferences.obo	(working copy)
@@ -90633,6 +90633,28 @@
 is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
 
 [Term]
+id: GO:1905636 ! positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding
+is_a: GO:1903025 {is_inferred="true"} ! regulation of RNA polymerase II regulatory region sequence-specific DNA binding
+is_a: GO:2000679 {is_inferred="true"} ! positive regulation of transcription regulatory region DNA binding
+
+[Term]
+id: GO:1905637 ! regulation of mitochondrial mRNA catabolic process
+is_a: GO:0000960 {is_inferred="true"} ! regulation of mitochondrial RNA catabolic process
+is_a: GO:0061013 {is_inferred="true"} ! regulation of mRNA catabolic process
+
+[Term]
+id: GO:1905638 ! negative regulation of mitochondrial mRNA catabolic process
+is_a: GO:0000961 {is_inferred="true"} ! negative regulation of mitochondrial RNA catabolic process
+is_a: GO:1902373 {is_inferred="true"} ! negative regulation of mRNA catabolic process
+is_a: GO:1905637 {is_inferred="true"} ! regulation of mitochondrial mRNA catabolic process
+
+[Term]
+id: GO:1905639 ! positive regulation of mitochondrial mRNA catabolic process
+is_a: GO:0000962 {is_inferred="true"} ! positive regulation of mitochondrial RNA catabolic process
+is_a: GO:0061014 {is_inferred="true"} ! positive regulation of mRNA catabolic process
+is_a: GO:1905637 {is_inferred="true"} ! regulation of mitochondrial mRNA catabolic process
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36793 | mcourtot | 2016-11-03 09:08:31 -0700 (Thu, 03 Nov 2016) | 1 line

fixed extra spaces as per release message LINE: 505717 accepting bad xref with spaces:<EC:4.2.1.-xref: MetaCyc:RXN-15755> and LINE: 82735 accepting bad xref with spaces:GOC: BHF_telomere 

changes in entailments

------------------------------------------------------------------------
r36764 | termgenie | 2016-11-02 15:25:45 -0700 (Wed, 02 Nov 2016) | 4 lines

TermGenie commit for user: als reviewed by tb

changes in entailments

------------------------------------------------------------------------
r36764 | termgenie | 2016-11-02 15:25:45 -0700 (Wed, 02 Nov 2016) | 4 lines

TermGenie commit for user: als reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36764)
+++ go_inferences.obo	(working copy)
@@ -90473,6 +90473,21 @@
 is_a: GO:1905600 {is_inferred="true"} ! regulation of receptor-mediated endocytosis involved in cholesterol transport
 
 [Term]
+id: GO:1905603 ! regulation of maintenance of permeability of blood-brain barrier
+is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0065008 {is_inferred="true"} ! regulation of biological quality
+
+[Term]
+id: GO:1905604 ! negative regulation of maintenance of permeability of blood-brain barrier
+is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
+is_a: GO:1905603 {is_inferred="true"} ! regulation of maintenance of permeability of blood-brain barrier
+
+[Term]
+id: GO:1905605 ! positive regulation of maintenance of permeability of blood-brain barrier
+is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
+is_a: GO:1905603 {is_inferred="true"} ! regulation of maintenance of permeability of blood-brain barrier
+
+[Term]
 id: GO:1905606 ! regulation of presynapse assembly
 is_a: GO:0051963 {is_inferred="true"} ! regulation of synapse assembly
 
------------------------------------------------------------------------
r36762 | tberardi | 2016-11-02 15:17:42 -0700 (Wed, 02 Nov 2016) | 1 line

GH12767 maintenance of blood-brain barrier and regulation terms - in progress

changes in entailments

------------------------------------------------------------------------
r36759 | dph | 2016-11-02 05:16:08 -0700 (Wed, 02 Nov 2016) | 2 lines

GH7774-closed

changes in entailments

------------------------------------------------------------------------
r36677 | tberardi | 2016-11-01 13:34:25 -0700 (Tue, 01 Nov 2016) | 1 line

GH12610 NTR component term: heteroreceptor complex - in progress

changes in entailments

------------------------------------------------------------------------
r36675 | tberardi | 2016-11-01 13:27:50 -0700 (Tue, 01 Nov 2016) | 1 line

GH12761 erroneous links involving spindle pole body terms - in progress

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36675)
+++ go_inferences.obo	(working copy)
@@ -75175,13 +75175,11 @@
 
 [Term]
 id: GO:1902440 ! protein localization to mitotic spindle pole body
-is_a: GO:1902480 {is_inferred="true"} ! protein localization to mitotic spindle
 is_a: GO:1905508 {is_inferred="true"} ! protein localization to microtubule organizing center
 
 [Term]
 id: GO:1902441 ! protein localization to meiotic spindle pole body
 is_a: GO:0022414 {is_inferred="true"} ! reproductive process
-is_a: GO:1905359 {is_inferred="true"} ! protein localization to meiotic spindle
 is_a: GO:1905508 {is_inferred="true"} ! protein localization to microtubule organizing center
 
 [Term]
------------------------------------------------------------------------
r36673 | tberardi | 2016-11-01 13:11:32 -0700 (Tue, 01 Nov 2016) | 1 line

GH12613 Term clarification: mycelium development

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36673)
+++ go_inferences.obo	(working copy)
@@ -72612,18 +72612,16 @@
 
 [Term]
 id: GO:1901922 ! regulation of sclerotium development
-is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
+is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
 
 [Term]
 id: GO:1901923 ! negative regulation of sclerotium development
 is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1901922 {is_inferred="true"} ! regulation of sclerotium development
 
 [Term]
 id: GO:1901924 ! positive regulation of sclerotium development
 is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1901922 {is_inferred="true"} ! regulation of sclerotium development
 
 [Term]
------------------------------------------------------------------------
r36671 | tberardi | 2016-11-01 12:59:53 -0700 (Tue, 01 Nov 2016) | 1 line

GH12764 basal pole of outer hair cell - closed

changes in entailments

------------------------------------------------------------------------
r36669 | termgenie | 2016-11-01 12:30:24 -0700 (Tue, 01 Nov 2016) | 2 lines

TermGenie commit for user: pga reviewed by dos

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36669)
+++ go_inferences.obo	(working copy)
@@ -55270,7 +55270,7 @@
 id: GO:0071922 ! regulation of cohesin loading
 is_a: GO:0007063 {is_inferred="true"} ! regulation of sister chromatid cohesion
 is_a: GO:0051101 {is_inferred="true"} ! regulation of DNA binding
-is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
+is_a: GO:1905634 {is_inferred="true"} ! regulation of protein localization to chromatin
 
 [Term]
 id: GO:0071923 ! negative regulation of cohesin loading
@@ -90601,6 +90601,27 @@
 is_a: GO:1905627 {is_inferred="true"} ! regulation of serotonin biosynthetic process
 
 [Term]
+id: GO:1905630 ! response to glyceraldehyde
+is_a: GO:0034284 {is_inferred="true"} ! response to monosaccharide
+
+[Term]
+id: GO:1905631 ! cellular response to glyceraldehyde
+is_a: GO:0071326 {is_inferred="true"} ! cellular response to monosaccharide stimulus
+is_a: GO:1905630 {is_inferred="true"} ! response to glyceraldehyde
+
+[Term]
+id: GO:1905632 ! protein localization to euchromatin
+is_a: GO:0071168 {is_inferred="true"} ! protein localization to chromatin
+
+[Term]
+id: GO:1905633 ! establishment of protein localization to euchromatin
+is_a: GO:0071169 {is_inferred="true"} ! establishment of protein localization to chromatin
+
+[Term]
+id: GO:1905634 ! regulation of protein localization to chromatin
+is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36660 | hjd | 2016-10-31 13:50:37 -0700 (Mon, 31 Oct 2016) | 2 lines

removed GO:0102638 duplicate name

changes in entailments

------------------------------------------------------------------------
r36655 | termgenie | 2016-10-31 09:12:48 -0700 (Mon, 31 Oct 2016) | 4 lines

TermGenie commit for user: pad reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36655)
+++ go_inferences.obo	(working copy)
@@ -90567,6 +90567,40 @@
 is_a: GO:2000024 {is_inferred="true"} ! regulation of leaf development
 
 [Term]
+id: GO:1905624 ! regulation of L-methionine import across plasma membrane
+is_a: GO:0010958 {is_inferred="true"} ! regulation of amino acid import
+is_a: GO:1903789 {is_inferred="true"} ! regulation of amino acid transmembrane transport
+
+[Term]
+id: GO:1905625 ! negative regulation of L-methionine import across plasma membrane
+is_a: GO:0034763 {is_inferred="true"} ! negative regulation of transmembrane transport
+is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
+is_a: GO:1905624 {is_inferred="true"} ! regulation of L-methionine import across plasma membrane
+
+[Term]
+id: GO:1905626 ! positive regulation of L-methionine import across plasma membrane
+is_a: GO:0034764 {is_inferred="true"} ! positive regulation of transmembrane transport
+is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
+is_a: GO:1905624 {is_inferred="true"} ! regulation of L-methionine import across plasma membrane
+
+[Term]
+id: GO:1905627 ! regulation of serotonin biosynthetic process
+is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
+is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
+
+[Term]
+id: GO:1905628 ! negative regulation of serotonin biosynthetic process
+is_a: GO:0031327 {is_inferred="true"} ! negative regulation of cellular biosynthetic process
+is_a: GO:0051172 {is_inferred="true"} ! negative regulation of nitrogen compound metabolic process
+is_a: GO:1905627 {is_inferred="true"} ! regulation of serotonin biosynthetic process
+
+[Term]
+id: GO:1905629 ! positive regulation of serotonin biosynthetic process
+is_a: GO:0031328 {is_inferred="true"} ! positive regulation of cellular biosynthetic process
+is_a: GO:0051173 {is_inferred="true"} ! positive regulation of nitrogen compound metabolic process
+is_a: GO:1905627 {is_inferred="true"} ! regulation of serotonin biosynthetic process
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36619 | termgenie | 2016-10-28 17:22:58 -0700 (Fri, 28 Oct 2016) | 2 lines

TermGenie commit for user: sp reviewed by tb

changes in entailments

------------------------------------------------------------------------
r36616 | termgenie | 2016-10-28 16:51:22 -0700 (Fri, 28 Oct 2016) | 3 lines

TermGenie commit for user: pga reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36616)
+++ go_inferences.obo	(working copy)
@@ -11399,6 +11399,7 @@
 id: GO:0010083 ! regulation of vegetative meristem growth
 is_a: GO:0010075 {is_inferred="true"} ! regulation of meristem growth
 is_a: GO:0048831 {is_inferred="true"} ! regulation of shoot system development
+is_a: GO:1905613 {is_inferred="true"} ! regulation of developmental vegetative growth
 
 [Term]
 id: GO:0010092 ! specification of animal organ identity
@@ -58010,6 +58011,7 @@
 [Term]
 id: GO:0090015 ! positive regulation of leaflet formation by auxin mediated signaling pathway
 is_a: GO:1905423 {is_inferred="true"} ! positive regulation of plant organ morphogenesis
+is_a: GO:1905623 {is_inferred="true"} ! positive regulation of leaf development
 
 [Term]
 id: GO:0090016 ! regulation of leaflet formation
@@ -62958,15 +62960,13 @@
 
 [Term]
 id: GO:1900056 ! negative regulation of leaf senescence
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1900055 {is_inferred="true"} ! regulation of leaf senescence
+is_a: GO:1905622 {is_inferred="true"} ! negative regulation of leaf development
 
 [Term]
 id: GO:1900057 ! positive regulation of leaf senescence
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1900055 {is_inferred="true"} ! regulation of leaf senescence
+is_a: GO:1905623 {is_inferred="true"} ! positive regulation of leaf development
 
 [Term]
 id: GO:1900058 ! regulation of sulfate assimilation
@@ -90079,17 +90079,17 @@
 
 [Term]
 id: GO:1905518 ! regulation of presynaptic active zone assembly
-is_a: GO:0051963 {is_inferred="true"} ! regulation of synapse assembly
+is_a: GO:1905606 {is_inferred="true"} ! regulation of presynapse assembly
 
 [Term]
 id: GO:1905519 ! negative regulation of presynaptic active zone assembly
-is_a: GO:0051964 {is_inferred="true"} ! negative regulation of synapse assembly
 is_a: GO:1905518 {is_inferred="true"} ! regulation of presynaptic active zone assembly
+is_a: GO:1905607 {is_inferred="true"} ! negative regulation of presynapse assembly
 
 [Term]
 id: GO:1905520 ! positive regulation of presynaptic active zone assembly
-is_a: GO:0051965 {is_inferred="true"} ! positive regulation of synapse assembly
 is_a: GO:1905518 {is_inferred="true"} ! regulation of presynaptic active zone assembly
+is_a: GO:1905608 {is_inferred="true"} ! positive regulation of presynapse assembly
 
 [Term]
 id: GO:1905521 ! regulation of macrophage migration
@@ -90477,6 +90477,96 @@
 is_a: GO:1905600 {is_inferred="true"} ! regulation of receptor-mediated endocytosis involved in cholesterol transport
 
 [Term]
+id: GO:1905606 ! regulation of presynapse assembly
+is_a: GO:0051963 {is_inferred="true"} ! regulation of synapse assembly
+
+[Term]
+id: GO:1905607 ! negative regulation of presynapse assembly
+is_a: GO:0051964 {is_inferred="true"} ! negative regulation of synapse assembly
+is_a: GO:1905606 {is_inferred="true"} ! regulation of presynapse assembly
+
+[Term]
+id: GO:1905608 ! positive regulation of presynapse assembly
+is_a: GO:0051965 {is_inferred="true"} ! positive regulation of synapse assembly
+is_a: GO:1905606 {is_inferred="true"} ! regulation of presynapse assembly
+
+[Term]
+id: GO:1905609 ! positive regulation of smooth muscle cell-matrix adhesion
+is_a: GO:0001954 {is_inferred="true"} ! positive regulation of cell-matrix adhesion
+is_a: GO:2000097 {is_inferred="true"} ! regulation of smooth muscle cell-matrix adhesion
+
+[Term]
+id: GO:1905610 ! regulation of mRNA cap binding
+is_a: GO:1905214 {is_inferred="true"} ! regulation of RNA binding
+
+[Term]
+id: GO:1905611 ! negative regulation of mRNA cap binding
+is_a: GO:1905215 {is_inferred="true"} ! negative regulation of RNA binding
+is_a: GO:1905610 {is_inferred="true"} ! regulation of mRNA cap binding
+
+[Term]
+id: GO:1905612 ! positive regulation of mRNA cap binding
+is_a: GO:1905216 {is_inferred="true"} ! positive regulation of RNA binding
+is_a: GO:1905610 {is_inferred="true"} ! regulation of mRNA cap binding
+
+[Term]
+id: GO:1905613 ! regulation of developmental vegetative growth
+is_a: GO:0048638 {is_inferred="true"} ! regulation of developmental growth
+
+[Term]
+id: GO:1905614 ! negative regulation of developmental vegetative growth
+is_a: GO:0048640 {is_inferred="true"} ! negative regulation of developmental growth
+is_a: GO:1905613 {is_inferred="true"} ! regulation of developmental vegetative growth
+
+[Term]
+id: GO:1905615 ! positive regulation of developmental vegetative growth
+is_a: GO:0048639 {is_inferred="true"} ! positive regulation of developmental growth
+is_a: GO:1905613 {is_inferred="true"} ! regulation of developmental vegetative growth
+
+[Term]
+id: GO:1905616 ! regulation of miRNA mediated inhibition of translation
+is_a: GO:0060964 {is_inferred="true"} ! regulation of gene silencing by miRNA
+
+[Term]
+id: GO:1905617 ! negative regulation of miRNA mediated inhibition of translation
+is_a: GO:0060965 {is_inferred="true"} ! negative regulation of gene silencing by miRNA
+is_a: GO:1905616 {is_inferred="true"} ! regulation of miRNA mediated inhibition of translation
+
+[Term]
+id: GO:1905618 ! positive regulation of miRNA mediated inhibition of translation
+is_a: GO:1905616 {is_inferred="true"} ! regulation of miRNA mediated inhibition of translation
+is_a: GO:2000637 {is_inferred="true"} ! positive regulation of gene silencing by miRNA
+
+[Term]
+id: GO:1905619 ! regulation of alpha-(1->3)-fucosyltransferase activity
+is_a: GO:0019222 {is_inferred="true"} ! regulation of metabolic process
+is_a: GO:0051338 {is_inferred="true"} ! regulation of transferase activity
+
+[Term]
+id: GO:1905620 ! negative regulation of alpha-(1->3)-fucosyltransferase activity
+is_a: GO:0009892 {is_inferred="true"} ! negative regulation of metabolic process
+is_a: GO:0051348 {is_inferred="true"} ! negative regulation of transferase activity
+is_a: GO:1905619 {is_inferred="true"} ! regulation of alpha-(1->3)-fucosyltransferase activity
+
+[Term]
+id: GO:1905621 ! positive regulation of alpha-(1->3)-fucosyltransferase activity
+is_a: GO:0009893 {is_inferred="true"} ! positive regulation of metabolic process
+is_a: GO:0051347 {is_inferred="true"} ! positive regulation of transferase activity
+is_a: GO:1905619 {is_inferred="true"} ! regulation of alpha-(1->3)-fucosyltransferase activity
+
+[Term]
+id: GO:1905622 ! negative regulation of leaf development
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
+is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
+is_a: GO:2000024 {is_inferred="true"} ! regulation of leaf development
+
+[Term]
+id: GO:1905623 ! positive regulation of leaf development
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
+is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
+is_a: GO:2000024 {is_inferred="true"} ! regulation of leaf development
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36591 | paola | 2016-10-27 08:02:56 -0700 (Thu, 27 Oct 2016) | 2 lines

GO:0043936 asexual sporulation resulting in the formation of a cellular spore #12744 - work in progress - added synonyms

changes in entailments

------------------------------------------------------------------------
r36589 | paola | 2016-10-27 07:48:19 -0700 (Thu, 27 Oct 2016) | 2 lines

GH Revise def: GO:0048315 conidium formation #12743 - closed

changes in entailments

------------------------------------------------------------------------
r36586 | paola | 2016-10-27 07:15:43 -0700 (Thu, 27 Oct 2016) | 2 lines

Fixing synonyms scope for GO:1902426

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36586)
+++ go_inferences.obo	(working copy)
@@ -75101,7 +75101,7 @@
 is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
 
 [Term]
-id: GO:1902426 ! negative regulation of mitotic spindle assembly checkpoint
+id: GO:1902426 ! deactivation of mitotic spindle assembly checkpoint
 is_a: GO:0045842 {is_inferred="true"} ! positive regulation of mitotic metaphase/anaphase transition
 is_a: GO:0045930 {is_inferred="true"} ! negative regulation of mitotic cell cycle
 is_a: GO:0090233 {is_inferred="true"} ! negative regulation of spindle checkpoint
------------------------------------------------------------------------
r36578 | paola | 2016-10-27 03:41:22 -0700 (Thu, 27 Oct 2016) | 3 lines

GH urate excretion #12759 - closed - added GO:0097744 urate salt excretion

changes in entailments

------------------------------------------------------------------------
r36573 | dph | 2016-10-26 12:34:20 -0700 (Wed, 26 Oct 2016) | 2 lines

Added synonyms to laminin complex terms.

changes in entailments

------------------------------------------------------------------------
r36570 | termgenie | 2016-10-26 12:19:47 -0700 (Wed, 26 Oct 2016) | 3 lines

TermGenie commit for user: nc reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36570)
+++ go_inferences.obo	(working copy)
@@ -90436,6 +90436,30 @@
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 
 [Term]
+id: GO:1905595 ! regulation of low-density lipoprotein particle receptor binding
+is_a: GO:1900120 {is_inferred="true"} ! regulation of receptor binding
+
+[Term]
+id: GO:1905596 ! negative regulation of low-density lipoprotein particle receptor binding
+is_a: GO:1900121 {is_inferred="true"} ! negative regulation of receptor binding
+is_a: GO:1905595 {is_inferred="true"} ! regulation of low-density lipoprotein particle receptor binding
+
+[Term]
+id: GO:1905597 ! positive regulation of low-density lipoprotein particle receptor binding
+is_a: GO:1900122 {is_inferred="true"} ! positive regulation of receptor binding
+is_a: GO:1905595 {is_inferred="true"} ! regulation of low-density lipoprotein particle receptor binding
+
+[Term]
+id: GO:1905598 ! negative regulation of low-density lipoprotein receptor activity
+is_a: GO:0048261 {is_inferred="true"} ! negative regulation of receptor-mediated endocytosis
+is_a: GO:2000272 {is_inferred="true"} ! negative regulation of receptor activity
+
+[Term]
+id: GO:1905599 ! positive regulation of low-density lipoprotein receptor activity
+is_a: GO:0048260 {is_inferred="true"} ! positive regulation of receptor-mediated endocytosis
+is_a: GO:2000273 {is_inferred="true"} ! positive regulation of receptor activity
+
+[Term]
 id: GO:1905600 ! regulation of receptor-mediated endocytosis involved in cholesterol transport
 is_a: GO:0032383 {is_inferred="true"} ! regulation of intracellular cholesterol transport
 is_a: GO:0048259 {is_inferred="true"} ! regulation of receptor-mediated endocytosis
------------------------------------------------------------------------
r36567 | dph | 2016-10-26 12:09:48 -0700 (Wed, 26 Oct 2016) | 2 lines

Added laminin5B complex.

changes in entailments

------------------------------------------------------------------------
r36563 | paola | 2016-10-26 08:28:44 -0700 (Wed, 26 Oct 2016) | 3 lines

GH OTR: Align GO and Reactome on ciliary processes #12487 - work in progress

changes in entailments

------------------------------------------------------------------------
r36561 | paola | 2016-10-26 07:57:19 -0700 (Wed, 26 Oct 2016) | 2 lines

GH OTR: Align GO and Reactome on ciliary processes #12487 - work in progress

changes in entailments

------------------------------------------------------------------------
r36559 | paola | 2016-10-26 07:41:52 -0700 (Wed, 26 Oct 2016) | 2 lines

GH OTR: Align GO and Reactome on ciliary processes #12487 - work in progress

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36559)
+++ go_inferences.obo	(working copy)
@@ -310,7 +310,7 @@
 
 [Term]
 id: GO:0000145 ! exocyst
-is_a: GO:0099023 {is_inferred="true"} ! tethring complex
+is_a: GO:0099023 {is_inferred="true"} ! tethering complex
 
 [Term]
 id: GO:0000147 ! actin cortical patch assembly
@@ -1009,7 +1009,7 @@
 [Term]
 id: GO:0000938 ! GARP complex
 is_a: GO:0044433 {is_inferred="true"} ! cytoplasmic vesicle part
-is_a: GO:0099023 {is_inferred="true"} ! tethring complex
+is_a: GO:0099023 {is_inferred="true"} ! tethering complex
 
 [Term]
 id: GO:0000941 ! condensed nuclear chromosome inner kinetochore
@@ -17116,7 +17116,7 @@
 
 [Term]
 id: GO:0017119 ! Golgi transport complex
-is_a: GO:0099023 {is_inferred="true"} ! tethring complex
+is_a: GO:0099023 {is_inferred="true"} ! tethering complex
 
 [Term]
 id: GO:0017122 ! protein N-acetylglucosaminyltransferase complex
@@ -20103,7 +20103,7 @@
 
 [Term]
 id: GO:0030008 ! TRAPP complex
-is_a: GO:0099023 {is_inferred="true"} ! tethring complex
+is_a: GO:0099023 {is_inferred="true"} ! tethering complex
 
 [Term]
 id: GO:0030015 ! CCR4-NOT core complex
@@ -21433,7 +21433,7 @@
 [Term]
 id: GO:0030897 ! HOPS complex
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
-is_a: GO:0099023 {is_inferred="true"} ! tethring complex
+is_a: GO:0099023 {is_inferred="true"} ! tethering complex
 
 [Term]
 id: GO:0030904 ! retromer complex
@@ -26686,7 +26686,7 @@
 
 [Term]
 id: GO:0033263 ! CORVET complex
-is_a: GO:0099023 {is_inferred="true"} ! tethring complex
+is_a: GO:0099023 {is_inferred="true"} ! tethering complex
 
 [Term]
 id: GO:0033265 ! choline binding
@@ -53090,7 +53090,7 @@
 
 [Term]
 id: GO:0070939 ! Dsl1/NZR complex
-is_a: GO:0099023 {is_inferred="true"} ! tethring complex
+is_a: GO:0099023 {is_inferred="true"} ! tethering complex
 
 [Term]
 id: GO:0070948 ! regulation of neutrophil mediated cytotoxicity
@@ -61730,7 +61730,7 @@
 is_a: GO:0044448 {is_inferred="true"} ! cell cortex part
 
 [Term]
-id: GO:0099023 ! tethring complex
+id: GO:0099023 ! tethering complex
 is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
 
 [Term]
------------------------------------------------------------------------
r36554 | termgenie | 2016-10-26 06:06:47 -0700 (Wed, 26 Oct 2016) | 4 lines

TermGenie commit for user: pr reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36555)
+++ go_inferences.obo	(working copy)
@@ -90436,6 +90436,23 @@
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 
 [Term]
+id: GO:1905600 ! regulation of receptor-mediated endocytosis involved in cholesterol transport
+is_a: GO:0032383 {is_inferred="true"} ! regulation of intracellular cholesterol transport
+is_a: GO:0048259 {is_inferred="true"} ! regulation of receptor-mediated endocytosis
+
+[Term]
+id: GO:1905601 ! negative regulation of receptor-mediated endocytosis involved in cholesterol transport
+is_a: GO:0032384 {is_inferred="true"} ! negative regulation of intracellular cholesterol transport
+is_a: GO:0048261 {is_inferred="true"} ! negative regulation of receptor-mediated endocytosis
+is_a: GO:1905600 {is_inferred="true"} ! regulation of receptor-mediated endocytosis involved in cholesterol transport
+
+[Term]
+id: GO:1905602 ! positive regulation of receptor-mediated endocytosis involved in cholesterol transport
+is_a: GO:0032385 {is_inferred="true"} ! positive regulation of intracellular cholesterol transport
+is_a: GO:0048260 {is_inferred="true"} ! positive regulation of receptor-mediated endocytosis
+is_a: GO:1905600 {is_inferred="true"} ! regulation of receptor-mediated endocytosis involved in cholesterol transport
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36553 | paola | 2016-10-26 06:00:14 -0700 (Wed, 26 Oct 2016) | 2 lines

GH OTR: capturing targets of endocytosis #12746 - work in progress (fixed synonym scope)

changes in entailments

------------------------------------------------------------------------
r36547 | paola | 2016-10-26 05:42:43 -0700 (Wed, 26 Oct 2016) | 3 lines

GH OTR: Align GO and Reactome on ciliary processes #12487 - work in progress

changes in entailments

------------------------------------------------------------------------
r36545 | paola | 2016-10-26 04:49:04 -0700 (Wed, 26 Oct 2016) | 3 lines

GH OTR: capturing targets of endocytosis #12746 - work in progress

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36545)
+++ go_inferences.obo	(working copy)
@@ -58324,8 +58324,8 @@
 is_a: GO:0006900 {is_inferred="true"} ! membrane budding
 
 [Term]
-id: GO:0090118 ! receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport
-is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
+id: GO:0090118 ! receptor-mediated endocytosis involved in cholesterol transport
+is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
 
 [Term]
 id: GO:0090119 ! vesicle-mediated cholesterol transport
------------------------------------------------------------------------
r36543 | paola | 2016-10-26 02:49:01 -0700 (Wed, 26 Oct 2016) | 3 lines

GH NTR negative regulation of ferrichrome biosynthetic process, in response to iron #12740 - closed - obsoleted GO:1905525

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36543)
+++ go_inferences.obo	(working copy)
@@ -90111,11 +90111,6 @@
 is_a: GO:1902498 {is_inferred="true"} ! regulation of protein autoubiquitination
 
 [Term]
-id: GO:1905525 ! regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron
-is_a: GO:0034396 {is_inferred="true"} ! negative regulation of transcription from RNA polymerase II promoter in response to iron
-is_a: GO:1905568 {is_inferred="true"} ! regulation of ferrichrome biosynthetic process
-
-[Term]
 id: GO:1905526 ! regulation of Golgi lumen acidification
 is_a: GO:0032847 {is_inferred="true"} ! regulation of cellular pH reduction
 
------------------------------------------------------------------------
r36540 | termgenie | 2016-10-25 17:46:08 -0700 (Tue, 25 Oct 2016) | 2 lines

TermGenie commit for user: pga reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36540)
+++ go_inferences.obo	(working copy)
@@ -90413,6 +90413,34 @@
 is_a: GO:0009827 {is_inferred="true"} ! plant-type cell wall modification
 
 [Term]
+id: GO:1905589 ! positive regulation of L-arginine import across plasma membrane
+is_a: GO:0034764 {is_inferred="true"} ! positive regulation of transmembrane transport
+is_a: GO:1902828 {is_inferred="true"} ! positive regulation of L-arginine import into cell
+is_a: GO:1905541 {is_inferred="true"} ! regulation of L-arginine import across plasma membrane
+
+[Term]
+id: GO:1905590 ! fibronectin fibril organization
+is_a: GO:0030198 {is_inferred="true"} ! extracellular matrix organization
+
+[Term]
+id: GO:1905591 ! regulation of optical nerve axon regeneration
+is_a: GO:0048679 {is_inferred="true"} ! regulation of axon regeneration
+
+[Term]
+id: GO:1905592 ! negative regulation of optical nerve axon regeneration
+is_a: GO:0048681 {is_inferred="true"} ! negative regulation of axon regeneration
+is_a: GO:1905591 {is_inferred="true"} ! regulation of optical nerve axon regeneration
+
+[Term]
+id: GO:1905593 ! positive regulation of optical nerve axon regeneration
+is_a: GO:0048680 {is_inferred="true"} ! positive regulation of axon regeneration
+is_a: GO:1905591 {is_inferred="true"} ! regulation of optical nerve axon regeneration
+
+[Term]
+id: GO:1905594 ! resveratrol binding
+is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36533 | paola | 2016-10-25 07:37:49 -0700 (Tue, 25 Oct 2016) | 2 lines

GH GO:0008280 cohesin core heterodimer #12598 - work in progress (merge)

changes in entailments

------------------------------------------------------------------------
r36528 | mcourtot | 2016-10-25 06:41:02 -0700 (Tue, 25 Oct 2016) | 1 line

cleaned up logical axioms phosphatase - again ;)

changes in entailments

------------------------------------------------------------------------
r36528 | mcourtot | 2016-10-25 06:41:02 -0700 (Tue, 25 Oct 2016) | 1 line

cleaned up logical axioms phosphatase - again ;)

changes in entailments

------------------------------------------------------------------------
r36523 | mcourtot | 2016-10-25 06:00:24 -0700 (Tue, 25 Oct 2016) | 1 line

added parentage to 'disulfide oxidoreductase activity' as per https://github.com/geneontology/go-ontology/issues/12752

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36523)
+++ go_inferences.obo	(working copy)
@@ -90393,20 +90393,24 @@
 
 [Term]
 id: GO:1905584 ! outer hair cell apoptotic process
-is_a: GO:0006915 {is_inferred="true"} ! apoptotic process
+is_a: GO:0051402 {is_inferred="true"} ! neuron apoptotic process
+is_a: GO:1904019 {is_inferred="true"} ! epithelial cell apoptotic process
 
 [Term]
 id: GO:1905585 ! regulation of outer hair cell apoptotic process
-is_a: GO:0042981 {is_inferred="true"} ! regulation of apoptotic process
+is_a: GO:0043523 {is_inferred="true"} ! regulation of neuron apoptotic process
+is_a: GO:1904035 {is_inferred="true"} ! regulation of epithelial cell apoptotic process
 
 [Term]
 id: GO:1905586 ! negative regulation of outer hair cell apoptotic process
-is_a: GO:0043066 {is_inferred="true"} ! negative regulation of apoptotic process
+is_a: GO:0043524 {is_inferred="true"} ! negative regulation of neuron apoptotic process
+is_a: GO:1904036 {is_inferred="true"} ! negative regulation of epithelial cell apoptotic process
 is_a: GO:1905585 {is_inferred="true"} ! regulation of outer hair cell apoptotic process
 
 [Term]
 id: GO:1905587 ! positive regulation of outer hair cell apoptotic process
-is_a: GO:0043065 {is_inferred="true"} ! positive regulation of apoptotic process
+is_a: GO:0043525 {is_inferred="true"} ! positive regulation of neuron apoptotic process
+is_a: GO:1904037 {is_inferred="true"} ! positive regulation of epithelial cell apoptotic process
 is_a: GO:1905585 {is_inferred="true"} ! regulation of outer hair cell apoptotic process
 
 [Term]
------------------------------------------------------------------------
r36511 | termgenie | 2016-10-24 17:32:29 -0700 (Mon, 24 Oct 2016) | 2 lines

TermGenie commit for user: lr reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36511)
+++ go_inferences.obo	(working copy)
@@ -90410,6 +90410,10 @@
 is_a: GO:1905585 {is_inferred="true"} ! regulation of outer hair cell apoptotic process
 
 [Term]
+id: GO:1905588 ! plant-type cell wall modification involved in stomatal movement
+is_a: GO:0009827 {is_inferred="true"} ! plant-type cell wall modification
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36509 | termgenie | 2016-10-24 17:20:07 -0700 (Mon, 24 Oct 2016) | 4 lines

TermGenie commit for user: sl reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36509)
+++ go_inferences.obo	(working copy)
@@ -90396,6 +90396,20 @@
 is_a: GO:0006915 {is_inferred="true"} ! apoptotic process
 
 [Term]
+id: GO:1905585 ! regulation of outer hair cell apoptotic process
+is_a: GO:0042981 {is_inferred="true"} ! regulation of apoptotic process
+
+[Term]
+id: GO:1905586 ! negative regulation of outer hair cell apoptotic process
+is_a: GO:0043066 {is_inferred="true"} ! negative regulation of apoptotic process
+is_a: GO:1905585 {is_inferred="true"} ! regulation of outer hair cell apoptotic process
+
+[Term]
+id: GO:1905587 ! positive regulation of outer hair cell apoptotic process
+is_a: GO:0043065 {is_inferred="true"} ! positive regulation of apoptotic process
+is_a: GO:1905585 {is_inferred="true"} ! regulation of outer hair cell apoptotic process
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36504 | dph | 2016-10-24 11:16:30 -0700 (Mon, 24 Oct 2016) | 2 lines

Added fibronectin fiber as part of completing GH12640.

changes in entailments

------------------------------------------------------------------------
r36504 | dph | 2016-10-24 11:16:30 -0700 (Mon, 24 Oct 2016) | 2 lines

Added fibronectin fiber as part of completing GH12640.

changes in entailments

------------------------------------------------------------------------
r36502 | dph | 2016-10-24 09:52:32 -0700 (Mon, 24 Oct 2016) | 2 lines

GH9135-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36502)
+++ go_inferences.obo	(working copy)
@@ -35375,10 +35375,6 @@
 is_a: GO:0016477 {is_inferred="true"} ! cell migration
 
 [Term]
-id: GO:0044324 ! regulation of transcription involved in anterior/posterior axis specification
-is_a: GO:0006355 {is_inferred="true"} ! regulation of transcription, DNA-templated
-
-[Term]
 id: GO:0044326 ! dendritic spine neck
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
------------------------------------------------------------------------
r36500 | mcourtot | 2016-10-24 08:05:23 -0700 (Mon, 24 Oct 2016) | 1 line

added positive and negative regulation of liquid surface tension as per https://github.com/geneontology/go-ontology/issues/12758

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36500)
+++ go_inferences.obo	(working copy)
@@ -62686,6 +62686,14 @@
 is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
+id: GO:0101028 ! positive regulation of liquid surface tension
+is_a: GO:0050828 {is_inferred="true"} ! regulation of liquid surface tension
+
+[Term]
+id: GO:0101029 ! negative regulation of liquid surface tension
+is_a: GO:0050828 {is_inferred="true"} ! regulation of liquid surface tension
+
+[Term]
 id: GO:1900000 ! regulation of anthocyanin catabolic process
 is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
 is_a: GO:0031537 {is_inferred="true"} ! regulation of anthocyanin metabolic process
------------------------------------------------------------------------
r36498 | mcourtot | 2016-10-24 07:30:07 -0700 (Mon, 24 Oct 2016) | 1 line

parentage syndecan binding as per https://github.com/geneontology/go-ontology/issues/12588

changes in entailments

------------------------------------------------------------------------
r36493 | dph | 2016-10-24 07:21:02 -0700 (Mon, 24 Oct 2016) | 2 lines

GH12699-closed

changes in entailments

------------------------------------------------------------------------
r36489 | mcourtot | 2016-10-24 03:21:29 -0700 (Mon, 24 Oct 2016) | 1 line

added GO_0101027, optical nerve axon regeneration as per https://github.com/geneontology/go-ontology/issues/12760

changes in entailments

------------------------------------------------------------------------
r36487 | termgenie | 2016-10-24 02:37:03 -0700 (Mon, 24 Oct 2016) | 2 lines

TermGenie commit for user: sl reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36487)
+++ go_inferences.obo	(working copy)
@@ -90379,6 +90379,19 @@
 is_a: GO:0010988 {is_inferred="true"} ! regulation of low-density lipoprotein particle clearance
 
 [Term]
+id: GO:1905582 ! response to mannose
+is_a: GO:0009746 {is_inferred="true"} ! response to hexose
+
+[Term]
+id: GO:1905583 ! cellular response to mannose
+is_a: GO:0071331 {is_inferred="true"} ! cellular response to hexose stimulus
+is_a: GO:1905582 {is_inferred="true"} ! response to mannose
+
+[Term]
+id: GO:1905584 ! outer hair cell apoptotic process
+is_a: GO:0006915 {is_inferred="true"} ! apoptotic process
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36462 | tberardi | 2016-10-21 16:30:33 -0700 (Fri, 21 Oct 2016) | 1 line

added term for FMN hydrolase activity

changes in entailments

------------------------------------------------------------------------
r36460 | tberardi | 2016-10-21 16:04:40 -0700 (Fri, 21 Oct 2016) | 1 line

added term for phosphomevalonate decarboxylase activity

changes in entailments

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r36444 | paola | 2016-10-21 04:15:41 -0700 (Fri, 21 Oct 2016) | 2 lines

Fixing error

changes in entailments

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r36440 | paola | 2016-10-21 02:26:06 -0700 (Fri, 21 Oct 2016) | 2 lines

Changing a has_part in starts_with

changes in entailments

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r36439 | paola | 2016-10-21 02:23:11 -0700 (Fri, 21 Oct 2016) | 3 lines

GH OTR: Align GO and Reactome on ciliary processes #12487 - work in progress - more edits

changes in entailments

------------------------------------------------------------------------
r36437 | paola | 2016-10-21 02:13:02 -0700 (Fri, 21 Oct 2016) | 3 lines

GH OTR: Align GO and Reactome on ciliary processes #12487 - work in progress - several edits

changes in entailments

------------------------------------------------------------------------
r36435 | termgenie | 2016-10-21 01:48:10 -0700 (Fri, 21 Oct 2016) | 4 lines

TermGenie commit for user: nc reviewed by pr

changes in entailments

------------------------------------------------------------------------
r36433 | termgenie | 2016-10-21 01:29:50 -0700 (Fri, 21 Oct 2016) | 2 lines

TermGenie commit for user: nc reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36433)
+++ go_inferences.obo	(working copy)
@@ -90374,6 +90374,11 @@
 is_a: GO:1905578 {is_inferred="true"} ! regulation of ERBB3 signaling pathway
 
 [Term]
+id: GO:1905581 ! positive regulation of low-density lipoprotein particle clearance
+is_a: GO:0010986 {is_inferred="true"} ! positive regulation of lipoprotein particle clearance
+is_a: GO:0010988 {is_inferred="true"} ! regulation of low-density lipoprotein particle clearance
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36429 | dph | 2016-10-20 17:19:40 -0700 (Thu, 20 Oct 2016) | 2 lines

GH12264-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36430)
+++ go_inferences.obo	(working copy)
@@ -8060,7 +8060,6 @@
 
 [Term]
 id: GO:0006895 ! Golgi to endosome transport
-is_a: GO:0006896 {is_inferred="true"} ! Golgi to vacuole transport
 is_a: GO:0016197 {is_inferred="true"} ! endosomal transport
 is_a: GO:0016482 {is_inferred="true"} ! cytosolic transport
 
@@ -8196,7 +8195,7 @@
 
 [Term]
 id: GO:0007032 ! endosome organization
-is_a: GO:0007033 {is_inferred="true"} ! vacuole organization
+is_a: GO:0016050 {is_inferred="true"} ! vesicle organization
 
 [Term]
 id: GO:0007033 ! vacuole organization
@@ -11207,7 +11206,8 @@
 
 [Term]
 id: GO:0010008 ! endosome membrane
-is_a: GO:0005774 {is_inferred="true"} ! vacuolar membrane
+is_a: GO:0098588 {is_inferred="true"} ! bounding membrane of organelle
+is_a: GO:0098805 {is_inferred="true"} ! whole membrane
 
 [Term]
 id: GO:0010009 ! cytoplasmic side of endosome membrane
@@ -16853,11 +16853,11 @@
 
 [Term]
 id: GO:0016189 ! synaptic vesicle to endosome fusion
-is_a: GO:0051469 {is_inferred="true"} ! vesicle fusion with vacuole
+is_a: GO:0048284 {is_inferred="true"} ! organelle fusion
 
 [Term]
 id: GO:0016197 ! endosomal transport
-is_a: GO:0007034 {is_inferred="true"} ! vacuolar transport
+is_a: GO:0006810 {is_inferred="true"} ! transport
 
 [Term]
 id: GO:0016202 ! regulation of striated muscle tissue development
@@ -22051,12 +22051,12 @@
 
 [Term]
 id: GO:0031302 ! intrinsic component of endosome membrane
-is_a: GO:0031310 {is_inferred="true"} ! intrinsic component of vacuolar membrane
+is_a: GO:0031300 {is_inferred="true"} ! intrinsic component of organelle membrane
 is_a: GO:0044440 {is_inferred="true"} ! endosomal part
 
 [Term]
 id: GO:0031303 ! integral component of endosome membrane
-is_a: GO:0031166 {is_inferred="true"} ! integral component of vacuolar membrane
+is_a: GO:0031301 {is_inferred="true"} ! integral component of organelle membrane
 is_a: GO:0031302 {is_inferred="true"} ! intrinsic component of endosome membrane
 
 [Term]
@@ -22093,10 +22093,6 @@
 is_a: GO:0044437 {is_inferred="true"} ! vacuolar part
 
 [Term]
-id: GO:0031313 ! extrinsic component of endosome membrane
-is_a: GO:0000306 {is_inferred="true"} ! extrinsic component of vacuolar membrane
-
-[Term]
 id: GO:0031321 ! ascospore-type prospore assembly
 is_a: GO:0003006 {is_inferred="true"} ! developmental process involved in reproduction
 is_a: GO:0010927 {is_inferred="true"} ! cellular component assembly involved in morphogenesis
@@ -22959,10 +22955,6 @@
 is_a: GO:0098805 {is_inferred="true"} ! whole membrane
 
 [Term]
-id: GO:0031904 ! endosome lumen
-is_a: GO:0005775 {is_inferred="true"} ! vacuolar lumen
-
-[Term]
 id: GO:0031913 ! contractile vacuole pore
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
@@ -24329,7 +24321,7 @@
 
 [Term]
 id: GO:0032439 ! endosome localization
-is_a: GO:0051640 {is_inferred="true"} ! organelle localization
+is_a: GO:0051648 {is_inferred="true"} ! vesicle localization
 
 [Term]
 id: GO:0032443 ! regulation of ergosterol biosynthetic process
@@ -30443,7 +30435,7 @@
 
 [Term]
 id: GO:0036010 ! protein localization to endosome
-is_a: GO:0072665 {is_inferred="true"} ! protein localization to vacuole
+is_a: GO:0033365 {is_inferred="true"} ! protein localization to organelle
 
 [Term]
 id: GO:0036035 ! osteoclast development
@@ -35544,7 +35536,7 @@
 
 [Term]
 id: GO:0044440 ! endosomal part
-is_a: GO:0044437 {is_inferred="true"} ! vacuolar part
+is_a: GO:0044433 {is_inferred="true"} ! cytoplasmic vesicle part
 
 [Term]
 id: GO:0044441 ! ciliary part
@@ -51179,8 +51171,7 @@
 
 [Term]
 id: GO:0061763 ! multivesicular body-lysosome fusion
-is_a: GO:0090174 {is_inferred="true"} ! organelle membrane fusion
-is_a: GO:0097576 {is_inferred="true"} ! vacuole fusion
+is_a: GO:0051469 {is_inferred="true"} ! vesicle fusion with vacuole
 
 [Term]
 id: GO:0061768 ! magnesium:sodium antiporter activity
@@ -60241,15 +60232,13 @@
 
 [Term]
 id: GO:0097488 ! multivesicular body, internal vesicle membrane
-is_a: GO:0044433 {is_inferred="true"} ! cytoplasmic vesicle part
 is_a: GO:0044440 {is_inferred="true"} ! endosomal part
 is_a: GO:0098588 {is_inferred="true"} ! bounding membrane of organelle
 
 [Term]
 id: GO:0097489 ! multivesicular body, internal vesicle lumen
-is_a: GO:0005775 {is_inferred="true"} ! vacuolar lumen
-is_a: GO:0044433 {is_inferred="true"} ! cytoplasmic vesicle part
 is_a: GO:0044440 {is_inferred="true"} ! endosomal part
+is_a: GO:0070013 {is_inferred="true"} ! intracellular organelle lumen
 
 [Term]
 id: GO:0097495 ! H-NS-Hha complex
@@ -61196,7 +61185,6 @@
 id: GO:0098866 ! multivesicular body fusion to apical plasma membrane
 is_a: GO:0045026 {is_inferred="true"} ! plasma membrane fusion
 is_a: GO:0090174 {is_inferred="true"} ! organelle membrane fusion
-is_a: GO:0097576 {is_inferred="true"} ! vacuole fusion
 
 [Term]
 id: GO:0098867 ! intramembranous bone growth
@@ -61605,7 +61593,7 @@
 is_a: GO:0016192 {is_inferred="true"} ! vesicle-mediated transport
 is_a: GO:0016197 {is_inferred="true"} ! endosomal transport
 is_a: GO:0035418 {is_inferred="true"} ! protein localization to synapse
-is_a: GO:0072666 {is_inferred="true"} ! establishment of protein localization to vacuole
+is_a: GO:0072594 {is_inferred="true"} ! establishment of protein localization to organelle
 is_a: GO:0099637 {is_inferred="true"} ! neurotransmitter receptor transport
 is_a: GO:1902946 {is_inferred="true"} ! protein localization to early endosome
 
@@ -62339,7 +62327,7 @@
 [Term]
 id: GO:0099646 ! neurotransmitter receptor transport, plasma membrane to endosome
 is_a: GO:0036010 {is_inferred="true"} ! protein localization to endosome
-is_a: GO:0072666 {is_inferred="true"} ! establishment of protein localization to vacuole
+is_a: GO:0072594 {is_inferred="true"} ! establishment of protein localization to organelle
 
 [Term]
 id: GO:0099703 ! induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration
@@ -75448,8 +75436,8 @@
 
 [Term]
 id: GO:1902502 ! multivesicular body HOPS complex
+is_a: GO:0030897 {is_inferred="true"} ! HOPS complex
 is_a: GO:0044440 {is_inferred="true"} ! endosomal part
-is_a: GO:1902500 {is_inferred="true"} ! vacuolar HOPS complex
 
 [Term]
 id: GO:1902503 ! adenylyltransferase complex
@@ -77622,13 +77610,11 @@
 [Term]
 id: GO:1902954 ! regulation of early endosome to recycling endosome transport
 is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
-is_a: GO:1903335 {is_inferred="true"} ! regulation of vacuolar transport
 is_a: GO:1903649 {is_inferred="true"} ! regulation of cytoplasmic transport
 
 [Term]
 id: GO:1902955 ! positive regulation of early endosome to recycling endosome transport
 is_a: GO:1902954 {is_inferred="true"} ! regulation of early endosome to recycling endosome transport
-is_a: GO:1903337 {is_inferred="true"} ! positive regulation of vacuolar transport
 is_a: GO:1903651 {is_inferred="true"} ! positive regulation of cytoplasmic transport
 
 [Term]
@@ -87471,7 +87457,7 @@
 
 [Term]
 id: GO:1904978 ! regulation of endosome organization
-is_a: GO:0044088 {is_inferred="true"} ! regulation of vacuole organization
+is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
 
 [Term]
 id: GO:1904979 ! negative regulation of endosome organization
@@ -87480,7 +87466,7 @@
 
 [Term]
 id: GO:1904980 ! positive regulation of endosome organization
-is_a: GO:0044090 {is_inferred="true"} ! positive regulation of vacuole organization
+is_a: GO:0010638 {is_inferred="true"} ! positive regulation of organelle organization
 is_a: GO:1904978 {is_inferred="true"} ! regulation of endosome organization
 
 [Term]
@@ -88932,18 +88918,15 @@
 [Term]
 id: GO:1905279 ! regulation of retrograde transport, endosome to Golgi
 is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
-is_a: GO:1903335 {is_inferred="true"} ! regulation of vacuolar transport
 is_a: GO:1903649 {is_inferred="true"} ! regulation of cytoplasmic transport
 
 [Term]
 id: GO:1905280 ! negative regulation of retrograde transport, endosome to Golgi
-is_a: GO:1903336 {is_inferred="true"} ! negative regulation of vacuolar transport
 is_a: GO:1903650 {is_inferred="true"} ! negative regulation of cytoplasmic transport
 is_a: GO:1905279 {is_inferred="true"} ! regulation of retrograde transport, endosome to Golgi
 
 [Term]
 id: GO:1905281 ! positive regulation of retrograde transport, endosome to Golgi
-is_a: GO:1903337 {is_inferred="true"} ! positive regulation of vacuolar transport
 is_a: GO:1903651 {is_inferred="true"} ! positive regulation of cytoplasmic transport
 is_a: GO:1905279 {is_inferred="true"} ! regulation of retrograde transport, endosome to Golgi
 
@@ -94657,18 +94640,15 @@
 [Term]
 id: GO:2000641 ! regulation of early endosome to late endosome transport
 is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
-is_a: GO:1903335 {is_inferred="true"} ! regulation of vacuolar transport
 is_a: GO:1903649 {is_inferred="true"} ! regulation of cytoplasmic transport
 
 [Term]
 id: GO:2000642 ! negative regulation of early endosome to late endosome transport
-is_a: GO:1903336 {is_inferred="true"} ! negative regulation of vacuolar transport
 is_a: GO:1903650 {is_inferred="true"} ! negative regulation of cytoplasmic transport
 is_a: GO:2000641 {is_inferred="true"} ! regulation of early endosome to late endosome transport
 
 [Term]
 id: GO:2000643 ! positive regulation of early endosome to late endosome transport
-is_a: GO:1903337 {is_inferred="true"} ! positive regulation of vacuolar transport
 is_a: GO:1903651 {is_inferred="true"} ! positive regulation of cytoplasmic transport
 is_a: GO:2000641 {is_inferred="true"} ! regulation of early endosome to late endosome transport
 
@@ -97151,16 +97131,15 @@
 [Term]
 id: GO:2001135 ! regulation of endocytic recycling
 is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
-is_a: GO:1903335 {is_inferred="true"} ! regulation of vacuolar transport
 
 [Term]
 id: GO:2001136 ! negative regulation of endocytic recycling
-is_a: GO:1903336 {is_inferred="true"} ! negative regulation of vacuolar transport
+is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
 is_a: GO:2001135 {is_inferred="true"} ! regulation of endocytic recycling
 
 [Term]
 id: GO:2001137 ! positive regulation of endocytic recycling
-is_a: GO:1903337 {is_inferred="true"} ! positive regulation of vacuolar transport
+is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
 is_a: GO:2001135 {is_inferred="true"} ! regulation of endocytic recycling
 
 [Term]
------------------------------------------------------------------------
r36428 | dph | 2016-10-20 17:10:41 -0700 (Thu, 20 Oct 2016) | 2 lines

GH12720-closed

changes in entailments

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r36419 | dph | 2016-10-20 08:28:37 -0700 (Thu, 20 Oct 2016) | 2 lines

GH12755-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36419)
+++ go_inferences.obo	(working copy)
@@ -90353,27 +90353,28 @@
 
 [Term]
 id: GO:1905572 ! ganglioside GM1 transport to membrane
-is_a: GO:0006810 {is_inferred="true"} ! transport
+is_a: GO:0035627 {is_inferred="true"} ! ceramide transport
+is_a: GO:0046836 {is_inferred="true"} ! glycolipid transport
 
 [Term]
 id: GO:1905573 ! ganglioside GM1 binding
-is_a: GO:0005488 {is_inferred="true"} ! binding
+is_a: GO:0035594 {is_inferred="true"} ! ganglioside binding
 
 [Term]
 id: GO:1905574 ! ganglioside GM2 binding
-is_a: GO:0005488 {is_inferred="true"} ! binding
+is_a: GO:0035594 {is_inferred="true"} ! ganglioside binding
 
 [Term]
 id: GO:1905575 ! ganglioside GM3 binding
-is_a: GO:0005488 {is_inferred="true"} ! binding
+is_a: GO:0035594 {is_inferred="true"} ! ganglioside binding
 
 [Term]
 id: GO:1905576 ! ganglioside GT1b binding
-is_a: GO:0005488 {is_inferred="true"} ! binding
+is_a: GO:0035594 {is_inferred="true"} ! ganglioside binding
 
 [Term]
 id: GO:1905577 ! ganglioside GP1c binding
-is_a: GO:0005488 {is_inferred="true"} ! binding
+is_a: GO:0035594 {is_inferred="true"} ! ganglioside binding
 
 [Term]
 id: GO:1905578 ! regulation of ERBB3 signaling pathway
------------------------------------------------------------------------
r36403 | termgenie | 2016-10-19 07:11:50 -0700 (Wed, 19 Oct 2016) | 4 lines

TermGenie commit for user: als reviewed by pr

changes in entailments

------------------------------------------------------------------------
r36403 | termgenie | 2016-10-19 07:11:50 -0700 (Wed, 19 Oct 2016) | 4 lines

TermGenie commit for user: als reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36403)
+++ go_inferences.obo	(working copy)
@@ -90376,6 +90376,20 @@
 is_a: GO:0005488 {is_inferred="true"} ! binding
 
 [Term]
+id: GO:1905578 ! regulation of ERBB3 signaling pathway
+is_a: GO:1901184 {is_inferred="true"} ! regulation of ERBB signaling pathway
+
+[Term]
+id: GO:1905579 ! negative regulation of ERBB3 signaling pathway
+is_a: GO:1901185 {is_inferred="true"} ! negative regulation of ERBB signaling pathway
+is_a: GO:1905578 {is_inferred="true"} ! regulation of ERBB3 signaling pathway
+
+[Term]
+id: GO:1905580 ! positive regulation of ERBB3 signaling pathway
+is_a: GO:1901186 {is_inferred="true"} ! positive regulation of ERBB signaling pathway
+is_a: GO:1905578 {is_inferred="true"} ! regulation of ERBB3 signaling pathway
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36401 | termgenie | 2016-10-19 07:04:46 -0700 (Wed, 19 Oct 2016) | 5 lines

TermGenie commit for user: pga reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36401)
+++ go_inferences.obo	(working copy)
@@ -90347,6 +90347,35 @@
 is_a: GO:1905568 {is_inferred="true"} ! regulation of ferrichrome biosynthetic process
 
 [Term]
+id: GO:1905571 ! interleukin-10 receptor complex
+is_a: GO:0043234 {is_inferred="true"} ! protein complex
+is_a: GO:0043235 {is_inferred="true"} ! receptor complex
+
+[Term]
+id: GO:1905572 ! ganglioside GM1 transport to membrane
+is_a: GO:0006810 {is_inferred="true"} ! transport
+
+[Term]
+id: GO:1905573 ! ganglioside GM1 binding
+is_a: GO:0005488 {is_inferred="true"} ! binding
+
+[Term]
+id: GO:1905574 ! ganglioside GM2 binding
+is_a: GO:0005488 {is_inferred="true"} ! binding
+
+[Term]
+id: GO:1905575 ! ganglioside GM3 binding
+is_a: GO:0005488 {is_inferred="true"} ! binding
+
+[Term]
+id: GO:1905576 ! ganglioside GT1b binding
+is_a: GO:0005488 {is_inferred="true"} ! binding
+
+[Term]
+id: GO:1905577 ! ganglioside GP1c binding
+is_a: GO:0005488 {is_inferred="true"} ! binding
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36394 | paola | 2016-10-19 06:23:23 -0700 (Wed, 19 Oct 2016) | 2 lines

GH NTR/OTR: multiciliation-related classes #12672 - work in progress - de novo centriole assembly terms

changes in entailments

------------------------------------------------------------------------
r36386 | paola | 2016-10-19 02:38:25 -0700 (Wed, 19 Oct 2016) | 3 lines

GH NTRs for ciliary CC terms: paraflagellar rod and mastigoneme #12733 - work in progress - added ‘paraflagellar rod’ and ‘mastigoneme’

changes in entailments

------------------------------------------------------------------------
r36386 | paola | 2016-10-19 02:38:25 -0700 (Wed, 19 Oct 2016) | 3 lines

GH NTRs for ciliary CC terms: paraflagellar rod and mastigoneme #12733 - work in progress - added ‘paraflagellar rod’ and ‘mastigoneme’

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36386)
+++ go_inferences.obo	(working copy)
@@ -60359,6 +60359,14 @@
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
 
 [Term]
+id: GO:0097740 ! paraflagellar rod
+is_a: GO:0044441 {is_inferred="true"} ! ciliary part
+
+[Term]
+id: GO:0097741 ! mastigoneme
+is_a: GO:0044441 {is_inferred="true"} ! ciliary part
+
+[Term]
 id: GO:0098003 ! viral tail assembly
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
 
------------------------------------------------------------------------
r36384 | paola | 2016-10-19 01:48:32 -0700 (Wed, 19 Oct 2016) | 2 lines

Removing stray links to morphogenesis terms

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36384)
+++ go_inferences.obo	(working copy)
@@ -8477,6 +8477,7 @@
 [Term]
 id: GO:0007288 ! sperm axoneme assembly
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0007289 ! spermatid nucleus differentiation
@@ -51774,10 +51775,6 @@
 is_a: GO:0070279 {is_inferred="true"} ! vitamin B6 binding
 
 [Term]
-id: GO:0070286 ! axonemal dynein complex assembly
-is_a: GO:0010927 {is_inferred="true"} ! cellular component assembly involved in morphogenesis
-
-[Term]
 id: GO:0070291 ! N-acylethanolamine metabolic process
 is_a: GO:0034308 {is_inferred="true"} ! primary alcohol metabolic process
 is_a: GO:0042439 {is_inferred="true"} ! ethanolamine-containing compound metabolic process
@@ -83442,7 +83439,7 @@
 
 [Term]
 id: GO:1904158 ! axonemal central apparatus assembly
-is_a: GO:0010927 {is_inferred="true"} ! cellular component assembly involved in morphogenesis
+is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
 
 [Term]
 id: GO:1904159 ! megasporocyte differentiation
------------------------------------------------------------------------
r36382 | paola | 2016-10-19 01:34:27 -0700 (Wed, 19 Oct 2016) | 2 lines

Fixing intersections post-merge

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36382)
+++ go_inferences.obo	(working copy)
@@ -35611,6 +35611,10 @@
 is_a: GO:0044464 {is_inferred="true"} ! cell part
 
 [Term]
+id: GO:0044458 ! motile cilium assembly
+is_a: GO:0060271 {is_inferred="true"} ! cilium assembly
+
+[Term]
 id: GO:0044459 ! plasma membrane part
 is_a: GO:0044425 {is_inferred="true"} ! membrane part
 is_a: GO:0044464 {is_inferred="true"} ! cell part
@@ -38062,7 +38066,6 @@
 [Term]
 id: GO:0045724 ! positive regulation of cilium assembly
 is_a: GO:0031346 {is_inferred="true"} ! positive regulation of cell projection organization
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:1902017 {is_inferred="true"} ! regulation of cilium assembly
 is_a: GO:1902117 {is_inferred="true"} ! positive regulation of organelle assembly
 
@@ -48149,6 +48152,12 @@
 is_a: GO:0060263 {is_inferred="true"} ! regulation of respiratory burst
 
 [Term]
+id: GO:0060271 ! cilium assembly
+is_a: GO:0030031 {is_inferred="true"} ! cell projection assembly
+is_a: GO:0044782 {is_inferred="true"} ! cilium organization
+is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
+
+[Term]
 id: GO:0060278 ! regulation of ovulation
 is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
@@ -73092,7 +73101,6 @@
 
 [Term]
 id: GO:1902017 ! regulation of cilium assembly
-is_a: GO:0022604 {is_inferred="true"} ! regulation of cell morphogenesis
 is_a: GO:0060491 {is_inferred="true"} ! regulation of cell projection assembly
 is_a: GO:1902115 {is_inferred="true"} ! regulation of organelle assembly
 
@@ -73099,7 +73107,6 @@
 [Term]
 id: GO:1902018 ! negative regulation of cilium assembly
 is_a: GO:0031345 {is_inferred="true"} ! negative regulation of cell projection organization
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:1902017 {is_inferred="true"} ! regulation of cilium assembly
 is_a: GO:1902116 {is_inferred="true"} ! negative regulation of organelle assembly
 
@@ -90070,6 +90077,10 @@
 is_a: GO:1905512 {is_inferred="true"} ! regulation of short-term synaptic potentiation
 
 [Term]
+id: GO:1905515 ! non-motile cilium assembly
+is_a: GO:0060271 {is_inferred="true"} ! cilium assembly
+
+[Term]
 id: GO:1905516 ! positive regulation of fertilization
 is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:0080154 {is_inferred="true"} ! regulation of fertilization
------------------------------------------------------------------------
r36364 | paola | 2016-10-18 08:55:30 -0700 (Tue, 18 Oct 2016) | 2 lines

GH NTR: substrate mycelium formation #12742 - work in progress - added PMID

changes in entailments

------------------------------------------------------------------------
r36364 | paola | 2016-10-18 08:55:30 -0700 (Tue, 18 Oct 2016) | 2 lines

GH NTR: substrate mycelium formation #12742 - work in progress - added PMID

changes in entailments

------------------------------------------------------------------------
r36362 | paola | 2016-10-18 08:03:55 -0700 (Tue, 18 Oct 2016) | 3 lines

GH NTR negative regulation of ferrichrome biosynthetic process, in response to iron #12740 - work in progress - added GO:0097739 negative regulation of ferrichrome biosynthetic process in response to iron

changes in entailments

------------------------------------------------------------------------
r36360 | termgenie | 2016-10-18 07:52:49 -0700 (Tue, 18 Oct 2016) | 4 lines

TermGenie commit for user: pr reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36360)
+++ go_inferences.obo	(working copy)
@@ -66176,17 +66176,17 @@
 
 [Term]
 id: GO:1900678 ! regulation of ferricrocin biosynthetic process
-is_a: GO:1900704 {is_inferred="true"} ! regulation of siderophore biosynthetic process
+is_a: GO:1905568 {is_inferred="true"} ! regulation of ferrichrome biosynthetic process
 
 [Term]
 id: GO:1900679 ! negative regulation of ferricrocin biosynthetic process
 is_a: GO:1900678 {is_inferred="true"} ! regulation of ferricrocin biosynthetic process
-is_a: GO:1900705 {is_inferred="true"} ! negative regulation of siderophore biosynthetic process
+is_a: GO:1905569 {is_inferred="true"} ! negative regulation of ferrichrome biosynthetic process
 
 [Term]
 id: GO:1900680 ! positive regulation of ferricrocin biosynthetic process
 is_a: GO:1900678 {is_inferred="true"} ! regulation of ferricrocin biosynthetic process
-is_a: GO:1900706 {is_inferred="true"} ! positive regulation of siderophore biosynthetic process
+is_a: GO:1905570 {is_inferred="true"} ! positive regulation of ferrichrome biosynthetic process
 
 [Term]
 id: GO:1900681 ! octadecene metabolic process
@@ -90133,7 +90133,7 @@
 [Term]
 id: GO:1905525 ! regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron
 is_a: GO:0034396 {is_inferred="true"} ! negative regulation of transcription from RNA polymerase II promoter in response to iron
-is_a: GO:1900704 {is_inferred="true"} ! regulation of siderophore biosynthetic process
+is_a: GO:1905568 {is_inferred="true"} ! regulation of ferrichrome biosynthetic process
 
 [Term]
 id: GO:1905526 ! regulation of Golgi lumen acidification
@@ -90335,6 +90335,20 @@
 is_a: GO:1905562 {is_inferred="true"} ! regulation of vascular endothelial cell proliferation
 
 [Term]
+id: GO:1905568 ! regulation of ferrichrome biosynthetic process
+is_a: GO:1900704 {is_inferred="true"} ! regulation of siderophore biosynthetic process
+
+[Term]
+id: GO:1905569 ! negative regulation of ferrichrome biosynthetic process
+is_a: GO:1900705 {is_inferred="true"} ! negative regulation of siderophore biosynthetic process
+is_a: GO:1905568 {is_inferred="true"} ! regulation of ferrichrome biosynthetic process
+
+[Term]
+id: GO:1905570 ! positive regulation of ferrichrome biosynthetic process
+is_a: GO:1900706 {is_inferred="true"} ! positive regulation of siderophore biosynthetic process
+is_a: GO:1905568 {is_inferred="true"} ! regulation of ferrichrome biosynthetic process
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36357 | paola | 2016-10-18 07:28:31 -0700 (Tue, 18 Oct 2016) | 2 lines

Removed extra synonyms from last commit

changes in entailments

------------------------------------------------------------------------
r36356 | paola | 2016-10-18 07:24:48 -0700 (Tue, 18 Oct 2016) | 3 lines

NTR: substrate mycelium formation #12742 - work in progress - added GO:0097738 substrate mycelium formation

changes in entailments

------------------------------------------------------------------------
r36354 | paola | 2016-10-18 06:25:52 -0700 (Tue, 18 Oct 2016) | 3 lines

GH term name consistency, kinetochore attachment #12738 - closed - edited terms as detailed in ticket

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36354)
+++ go_inferences.obo	(working copy)
@@ -75097,22 +75097,22 @@
 is_a: GO:1902421 {is_inferred="true"} ! hydrogen metabolic process
 
 [Term]
-id: GO:1902423 ! regulation of mitotic attachment of spindle microtubules to kinetochore
+id: GO:1902423 ! regulation of attachment of mitotic spindle microtubules to kinetochore
 is_a: GO:0033047 {is_inferred="true"} ! regulation of mitotic sister chromatid segregation
 is_a: GO:0051988 {is_inferred="true"} ! regulation of attachment of spindle microtubules to kinetochore
 is_a: GO:0090235 {is_inferred="true"} ! regulation of metaphase plate congression
 
 [Term]
-id: GO:1902424 ! negative regulation of mitotic attachment of spindle microtubules to kinetochore
+id: GO:1902424 ! negative regulation of attachment of mitotic spindle microtubules to kinetochore
 is_a: GO:0033048 {is_inferred="true"} ! negative regulation of mitotic sister chromatid segregation
 is_a: GO:0051986 {is_inferred="true"} ! negative regulation of attachment of spindle microtubules to kinetochore
-is_a: GO:1902423 {is_inferred="true"} ! regulation of mitotic attachment of spindle microtubules to kinetochore
+is_a: GO:1902423 {is_inferred="true"} ! regulation of attachment of mitotic spindle microtubules to kinetochore
 
 [Term]
 id: GO:1902425 ! positive regulation of attachment of mitotic spindle microtubules to kinetochore
 is_a: GO:0045840 {is_inferred="true"} ! positive regulation of mitotic nuclear division
 is_a: GO:0051987 {is_inferred="true"} ! positive regulation of attachment of spindle microtubules to kinetochore
-is_a: GO:1902423 {is_inferred="true"} ! regulation of mitotic attachment of spindle microtubules to kinetochore
+is_a: GO:1902423 {is_inferred="true"} ! regulation of attachment of mitotic spindle microtubules to kinetochore
 is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
 
 [Term]
@@ -88146,7 +88146,7 @@
 
 [Term]
 id: GO:1905115 ! regulation of lateral attachment of mitotic spindle microtubules to kinetochore
-is_a: GO:1902423 {is_inferred="true"} ! regulation of mitotic attachment of spindle microtubules to kinetochore
+is_a: GO:1902423 {is_inferred="true"} ! regulation of attachment of mitotic spindle microtubules to kinetochore
 
 [Term]
 id: GO:1905116 ! positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore
------------------------------------------------------------------------
r36346 | tberardi | 2016-10-17 17:30:07 -0700 (Mon, 17 Oct 2016) | 1 line

GH11313 cleaning up plant-type sporogenesis

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36346)
+++ go_inferences.obo	(working copy)
@@ -42481,9 +42481,8 @@
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 
 [Term]
-id: GO:0048236 ! plant-type spore development
-is_a: GO:0003006 {is_inferred="true"} ! developmental process involved in reproduction
-is_a: GO:0048856 {is_inferred="true"} ! anatomical structure development
+id: GO:0048236 ! plant-type sporogenesis
+is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
 id: GO:0048237 ! rough endoplasmic reticulum lumen
------------------------------------------------------------------------
r36344 | termgenie | 2016-10-17 13:18:47 -0700 (Mon, 17 Oct 2016) | 4 lines

TermGenie commit for user: nc reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36344)
+++ go_inferences.obo	(working copy)
@@ -90322,6 +90322,20 @@
 is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
 
 [Term]
+id: GO:1905562 ! regulation of vascular endothelial cell proliferation
+is_a: GO:0001936 {is_inferred="true"} ! regulation of endothelial cell proliferation
+
+[Term]
+id: GO:1905563 ! negative regulation of vascular endothelial cell proliferation
+is_a: GO:0001937 {is_inferred="true"} ! negative regulation of endothelial cell proliferation
+is_a: GO:1905562 {is_inferred="true"} ! regulation of vascular endothelial cell proliferation
+
+[Term]
+id: GO:1905564 ! positive regulation of vascular endothelial cell proliferation
+is_a: GO:0001938 {is_inferred="true"} ! positive regulation of endothelial cell proliferation
+is_a: GO:1905562 {is_inferred="true"} ! regulation of vascular endothelial cell proliferation
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36336 | paola | 2016-10-17 02:39:31 -0700 (Mon, 17 Oct 2016) | 2 lines

Fixing ASCII error

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36336)
+++ go_inferences.obo	(working copy)
@@ -30032,7 +30032,7 @@
 is_a: GO:0005488 {is_inferred="true"} ! binding
 
 [Term]
-id: GO:0035735 ! intraciliary transport involved in cilium morphogenesis
+id: GO:0035735 ! intraciliary transport involved in cilium assembly
 is_a: GO:0042073 {is_inferred="true"} ! intraciliary transport
 
 [Term]
------------------------------------------------------------------------
r36333 | termgenie | 2016-10-17 00:27:33 -0700 (Mon, 17 Oct 2016) | 4 lines

TermGenie commit for user: pad reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36333)
+++ go_inferences.obo	(working copy)
@@ -15089,10 +15089,6 @@
 is_a: GO:0005371 {is_inferred="true"} ! tricarboxylate secondary active transmembrane transporter activity
 
 [Term]
-id: GO:0015520 ! tetracycline:proton antiporter activity
-is_a: GO:1901618 {is_inferred="true"} ! organic hydroxy compound transmembrane transporter activity
-
-[Term]
 id: GO:0015523 ! arabinose efflux transmembrane transporter activity
 is_a: GO:0015562 {is_inferred="true"} ! efflux transmembrane transporter activity
 is_a: GO:0042900 {is_inferred="true"} ! arabinose transmembrane transporter activity
@@ -16170,7 +16166,7 @@
 
 [Term]
 id: GO:0015904 ! tetracycline transport
-is_a: GO:0015850 {is_inferred="true"} ! organic hydroxy compound transport
+is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 
 [Term]
 id: GO:0015905 ! bicyclomycin transport
@@ -17200,11 +17196,7 @@
 
 [Term]
 id: GO:0018189 ! pyrroloquinoline quinone biosynthetic process
-is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
 is_a: GO:0072351 {is_inferred="true"} ! tricarboxylic acid biosynthetic process
-is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
-is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
-is_a: GO:1901663 {is_inferred="true"} ! quinone biosynthetic process
 
 [Term]
 id: GO:0018396 ! peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine
@@ -17693,6 +17685,10 @@
 is_a: GO:0032787 {is_inferred="true"} ! monocarboxylic acid metabolic process
 
 [Term]
+id: GO:0018981 ! triethanolamine metabolic process
+is_a: GO:0019751 {is_inferred="true"} ! polyol metabolic process
+
+[Term]
 id: GO:0018982 ! vanillin metabolic process
 is_a: GO:0006081 {is_inferred="true"} ! cellular aldehyde metabolic process
 is_a: GO:0018904 {is_inferred="true"} ! ether metabolic process
@@ -26211,15 +26207,21 @@
 
 [Term]
 id: GO:0033069 ! ansamycin metabolic process
-is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
 is_a: GO:0030638 {is_inferred="true"} ! polyketide metabolic process
+is_a: GO:0043603 {is_inferred="true"} ! cellular amide metabolic process
 is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
+is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
+is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
+is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
 
 [Term]
 id: GO:0033070 ! ansamycin biosynthetic process
+is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
 is_a: GO:0030639 {is_inferred="true"} ! polyketide biosynthetic process
 is_a: GO:0033069 {is_inferred="true"} ! ansamycin metabolic process
-is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
+is_a: GO:0043604 {is_inferred="true"} ! amide biosynthetic process
+is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
+is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
 
 [Term]
 id: GO:0033071 ! vancomycin metabolic process
@@ -26877,11 +26879,13 @@
 id: GO:0033329 ! kaempferol O-glucoside metabolic process
 is_a: GO:0051552 {is_inferred="true"} ! flavone metabolic process
 is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
+is_a: GO:1901804 {is_inferred="true"} ! beta-glucoside metabolic process
 
 [Term]
 id: GO:0033330 ! kaempferol O-glucoside biosynthetic process
 is_a: GO:0051553 {is_inferred="true"} ! flavone biosynthetic process
 is_a: GO:1901617 {is_inferred="true"} ! organic hydroxy compound biosynthetic process
+is_a: GO:1901806 {is_inferred="true"} ! beta-glucoside biosynthetic process
 
 [Term]
 id: GO:0033331 ! ent-kaurene metabolic process
@@ -30642,22 +30646,19 @@
 
 [Term]
 id: GO:0036182 ! asperthecin metabolic process
-is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
-is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
+is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
 is_a: GO:1901661 {is_inferred="true"} ! quinone metabolic process
 
 [Term]
 id: GO:0036183 ! asperthecin catabolic process
-is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
+is_a: GO:0019336 {is_inferred="true"} ! phenol-containing compound catabolic process
 is_a: GO:0036182 {is_inferred="true"} ! asperthecin metabolic process
-is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
 is_a: GO:1901662 {is_inferred="true"} ! quinone catabolic process
 
 [Term]
 id: GO:0036184 ! asperthecin biosynthetic process
-is_a: GO:0019438 {is_inferred="true"} ! aromatic compound biosynthetic process
 is_a: GO:0036182 {is_inferred="true"} ! asperthecin metabolic process
-is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
+is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
 is_a: GO:1901663 {is_inferred="true"} ! quinone biosynthetic process
 
 [Term]
@@ -34907,7 +34908,6 @@
 
 [Term]
 id: GO:0043643 ! tetracycline metabolic process
-is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
 is_a: GO:0030638 {is_inferred="true"} ! polyketide metabolic process
 is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
 
@@ -34915,7 +34915,6 @@
 id: GO:0043644 ! tetracycline biosynthetic process
 is_a: GO:0030639 {is_inferred="true"} ! polyketide biosynthetic process
 is_a: GO:0043643 {is_inferred="true"} ! tetracycline metabolic process
-is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
 
 [Term]
 id: GO:0043645 ! cephalosporin metabolic process
@@ -35699,12 +35698,16 @@
 
 [Term]
 id: GO:0044597 ! daunorubicin metabolic process
+is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
 is_a: GO:0030638 {is_inferred="true"} ! polyketide metabolic process
+is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
 is_a: GO:1901661 {is_inferred="true"} ! quinone metabolic process
 
 [Term]
 id: GO:0044598 ! doxorubicin metabolic process
+is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
 is_a: GO:0030638 {is_inferred="true"} ! polyketide metabolic process
+is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
 is_a: GO:1901661 {is_inferred="true"} ! quinone metabolic process
 
 [Term]
@@ -40292,7 +40295,7 @@
 [Term]
 id: GO:0046267 ! triethanolamine catabolic process
 is_a: GO:0018981 {is_inferred="true"} ! triethanolamine metabolic process
-is_a: GO:0046164 {is_inferred="true"} ! alcohol catabolic process
+is_a: GO:0046174 {is_inferred="true"} ! polyol catabolic process
 is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
 
 [Term]
@@ -47301,21 +47304,23 @@
 
 [Term]
 id: GO:0052698 ! ergothioneine metabolic process
+is_a: GO:0000096 {is_inferred="true"} ! sulfur amino acid metabolic process
 is_a: GO:0006577 {is_inferred="true"} ! amino-acid betaine metabolic process
 
 [Term]
 id: GO:0052699 ! ergothioneine biosynthetic process
+is_a: GO:0000097 {is_inferred="true"} ! sulfur amino acid biosynthetic process
 is_a: GO:0006578 {is_inferred="true"} ! amino-acid betaine biosynthetic process
 is_a: GO:0052698 {is_inferred="true"} ! ergothioneine metabolic process
 
 [Term]
 id: GO:0052700 ! ergothioneine catabolic process
+is_a: GO:0000098 {is_inferred="true"} ! sulfur amino acid catabolic process
 is_a: GO:0006579 {is_inferred="true"} ! amino-acid betaine catabolic process
 is_a: GO:0052698 {is_inferred="true"} ! ergothioneine metabolic process
 
 [Term]
 id: GO:0052704 ! ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine
-is_a: GO:0044711 {is_inferred="true"} ! single-organism biosynthetic process
 is_a: GO:0052805 {is_inferred="true"} ! imidazole-containing compound catabolic process
 is_a: GO:1901606 {is_inferred="true"} ! alpha-amino acid catabolic process
 
@@ -47340,10 +47345,6 @@
 is_a: GO:1901606 {is_inferred="true"} ! alpha-amino acid catabolic process
 
 [Term]
-id: GO:0052711 ! ergothioneine biosynthesis from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine
-is_a: GO:0044711 {is_inferred="true"} ! single-organism biosynthetic process
-
-[Term]
 id: GO:0052718 ! tRNA-specific adenosine-34 deaminase complex
 is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
 
@@ -52275,7 +52276,7 @@
 
 [Term]
 id: GO:0070538 ! oleic acid binding
-is_a: GO:0036041 {is_inferred="true"} ! long-chain fatty acid binding
+is_a: GO:0005504 {is_inferred="true"} ! fatty acid binding
 
 [Term]
 id: GO:0070539 ! linoleic acid binding
@@ -53231,9 +53232,6 @@
 [Term]
 id: GO:0070968 ! pyrroloquinoline quinone binding
 is_a: GO:0031406 {is_inferred="true"} ! carboxylic acid binding
-is_a: GO:0048038 {is_inferred="true"} ! quinone binding
-is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
-is_a: GO:1901363 {is_inferred="true"} ! heterocyclic compound binding
 
 [Term]
 id: GO:0070972 ! protein localization to endoplasmic reticulum
@@ -56725,7 +56723,6 @@
 
 [Term]
 id: GO:0072746 ! cellular response to tetracycline
-is_a: GO:0071407 {is_inferred="true"} ! cellular response to organic cyclic compound
 is_a: GO:1901326 {is_inferred="true"} ! response to tetracycline
 is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
 
@@ -56809,6 +56806,10 @@
 is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
 
 [Term]
+id: GO:0072763 ! cellular response to hesperadin
+is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
+
+[Term]
 id: GO:0072764 ! cellular response to reversine
 is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
 
@@ -65697,6 +65698,7 @@
 
 [Term]
 id: GO:1900594 ! (+)-kotanin metabolic process
+is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
 is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
 is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
 is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
@@ -65703,6 +65705,7 @@
 
 [Term]
 id: GO:1900595 ! (+)-kotanin catabolic process
+is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
 is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
 is_a: GO:1900594 {is_inferred="true"} ! (+)-kotanin metabolic process
 is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
@@ -65710,11 +65713,13 @@
 [Term]
 id: GO:1900596 ! (+)-kotanin biosynthetic process
 is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
+is_a: GO:0019438 {is_inferred="true"} ! aromatic compound biosynthetic process
 is_a: GO:1900594 {is_inferred="true"} ! (+)-kotanin metabolic process
 is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
 
 [Term]
 id: GO:1900597 ! demethylkotanin metabolic process
+is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
 is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
 is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
 is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
@@ -65721,6 +65726,7 @@
 
 [Term]
 id: GO:1900598 ! demethylkotanin catabolic process
+is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
 is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
 is_a: GO:1900597 {is_inferred="true"} ! demethylkotanin metabolic process
 is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
@@ -65728,6 +65734,7 @@
 [Term]
 id: GO:1900599 ! demethylkotanin biosynthetic process
 is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
+is_a: GO:0019438 {is_inferred="true"} ! aromatic compound biosynthetic process
 is_a: GO:1900597 {is_inferred="true"} ! demethylkotanin metabolic process
 is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
 
@@ -66814,6 +66821,7 @@
 is_a: GO:0009820 {is_inferred="true"} ! alkaloid metabolic process
 is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
 is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
+is_a: GO:1901615 {is_inferred="true"} ! organic hydroxy compound metabolic process
 is_a: GO:1901661 {is_inferred="true"} ! quinone metabolic process
 
 [Term]
@@ -66822,6 +66830,7 @@
 is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
 is_a: GO:1900794 {is_inferred="true"} ! terrequinone A metabolic process
 is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
+is_a: GO:1901616 {is_inferred="true"} ! organic hydroxy compound catabolic process
 is_a: GO:1901662 {is_inferred="true"} ! quinone catabolic process
 
 [Term]
@@ -66830,6 +66839,7 @@
 is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
 is_a: GO:1900794 {is_inferred="true"} ! terrequinone A metabolic process
 is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
+is_a: GO:1901617 {is_inferred="true"} ! organic hydroxy compound biosynthetic process
 is_a: GO:1901663 {is_inferred="true"} ! quinone biosynthetic process
 
 [Term]
@@ -66854,24 +66864,21 @@
 id: GO:1900800 ! cspyrone B1 metabolic process
 is_a: GO:0006082 {is_inferred="true"} ! organic acid metabolic process
 is_a: GO:0042180 {is_inferred="true"} ! cellular ketone metabolic process
-is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
-is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
+is_a: GO:1901334 {is_inferred="true"} ! lactone metabolic process
 
 [Term]
 id: GO:1900801 ! cspyrone B1 catabolic process
 is_a: GO:0016054 {is_inferred="true"} ! organic acid catabolic process
 is_a: GO:0042182 {is_inferred="true"} ! ketone catabolic process
-is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
 is_a: GO:1900800 {is_inferred="true"} ! cspyrone B1 metabolic process
-is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
+is_a: GO:1901335 {is_inferred="true"} ! lactone catabolic process
 
 [Term]
 id: GO:1900802 ! cspyrone B1 biosynthetic process
 is_a: GO:0016053 {is_inferred="true"} ! organic acid biosynthetic process
-is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
 is_a: GO:0042181 {is_inferred="true"} ! ketone biosynthetic process
 is_a: GO:1900800 {is_inferred="true"} ! cspyrone B1 metabolic process
-is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
+is_a: GO:1901336 {is_inferred="true"} ! lactone biosynthetic process
 
 [Term]
 id: GO:1900803 ! brevianamide F metabolic process
@@ -66981,6 +66988,7 @@
 
 [Term]
 id: GO:1900819 ! orlandin metabolic process
+is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
 is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
 is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
 is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
@@ -66987,6 +66995,7 @@
 
 [Term]
 id: GO:1900820 ! orlandin catabolic process
+is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
 is_a: GO:0046700 {is_inferred="true"} ! heterocycle catabolic process
 is_a: GO:1900819 {is_inferred="true"} ! orlandin metabolic process
 is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
@@ -66994,6 +67003,7 @@
 [Term]
 id: GO:1900821 ! orlandin biosynthetic process
 is_a: GO:0018130 {is_inferred="true"} ! heterocycle biosynthetic process
+is_a: GO:0019438 {is_inferred="true"} ! aromatic compound biosynthetic process
 is_a: GO:1900819 {is_inferred="true"} ! orlandin metabolic process
 is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
 
@@ -69606,7 +69616,7 @@
 
 [Term]
 id: GO:1901326 ! response to tetracycline
-is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
+is_a: GO:0010033 {is_inferred="true"} ! response to organic substance
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
 [Term]
@@ -70940,6 +70950,7 @@
 id: GO:1901595 ! response to hesperadin
 is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
 is_a: GO:0014075 {is_inferred="true"} ! response to amine
+is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
 [Term]
 id: GO:1901596 ! response to reversine
@@ -71788,13 +71799,10 @@
 
 [Term]
 id: GO:1901761 ! oxytetracycline metabolic process
-is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
 is_a: GO:0030638 {is_inferred="true"} ! polyketide metabolic process
-is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
 
 [Term]
 id: GO:1901762 ! oxytetracycline catabolic process
-is_a: GO:0019336 {is_inferred="true"} ! phenol-containing compound catabolic process
 is_a: GO:0030640 {is_inferred="true"} ! polyketide catabolic process
 is_a: GO:1901761 {is_inferred="true"} ! oxytetracycline metabolic process
 
@@ -71801,7 +71809,6 @@
 [Term]
 id: GO:1901763 ! oxytetracycline biosynthetic process
 is_a: GO:0030639 {is_inferred="true"} ! polyketide biosynthetic process
-is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
 is_a: GO:1901761 {is_inferred="true"} ! oxytetracycline metabolic process
 
 [Term]
@@ -71834,14 +71841,18 @@
 
 [Term]
 id: GO:1901770 ! daunorubicin catabolic process
+is_a: GO:0019439 {is_inferred="true"} ! aromatic compound catabolic process
 is_a: GO:0030640 {is_inferred="true"} ! polyketide catabolic process
 is_a: GO:0030649 {is_inferred="true"} ! aminoglycoside antibiotic catabolic process
+is_a: GO:1901361 {is_inferred="true"} ! organic cyclic compound catabolic process
 is_a: GO:1901662 {is_inferred="true"} ! quinone catabolic process
 
 [Term]
 id: GO:1901771 ! daunorubicin biosynthetic process
+is_a: GO:0019438 {is_inferred="true"} ! aromatic compound biosynthetic process
 is_a: GO:0030639 {is_inferred="true"} ! polyketide biosynthetic process
 is_a: GO:0030648 {is_inferred="true"} ! aminoglycoside antibiotic biosynthetic process
+is_a: GO:1901362 {is_inferred="true"} ! organic cyclic compound biosynthetic process
 is_a: GO:1901663 {is_inferred="true"} ! quinone biosynthetic process
 
 [Term]
@@ -73714,10 +73725,12 @@
 [Term]
 id: GO:1902133 ! (+)-secoisolariciresinol metabolic process
 is_a: GO:0009806 {is_inferred="true"} ! lignan metabolic process
+is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
 is_a: GO:0034311 {is_inferred="true"} ! diol metabolic process
 
 [Term]
 id: GO:1902134 ! (+)-secoisolariciresinol catabolic process
+is_a: GO:0019336 {is_inferred="true"} ! phenol-containing compound catabolic process
 is_a: GO:0034313 {is_inferred="true"} ! diol catabolic process
 is_a: GO:0046273 {is_inferred="true"} ! lignan catabolic process
 is_a: GO:1902133 {is_inferred="true"} ! (+)-secoisolariciresinol metabolic process
@@ -73726,15 +73739,18 @@
 id: GO:1902135 ! (+)-secoisolariciresinol biosynthetic process
 is_a: GO:0009807 {is_inferred="true"} ! lignan biosynthetic process
 is_a: GO:0034312 {is_inferred="true"} ! diol biosynthetic process
+is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
 is_a: GO:1902133 {is_inferred="true"} ! (+)-secoisolariciresinol metabolic process
 
 [Term]
 id: GO:1902136 ! (-)-secoisolariciresinol metabolic process
 is_a: GO:0009806 {is_inferred="true"} ! lignan metabolic process
+is_a: GO:0018958 {is_inferred="true"} ! phenol-containing compound metabolic process
 is_a: GO:0034311 {is_inferred="true"} ! diol metabolic process
 
 [Term]
 id: GO:1902137 ! (-)-secoisolariciresinol catabolic process
+is_a: GO:0019336 {is_inferred="true"} ! phenol-containing compound catabolic process
 is_a: GO:0034313 {is_inferred="true"} ! diol catabolic process
 is_a: GO:0046273 {is_inferred="true"} ! lignan catabolic process
 is_a: GO:1902136 {is_inferred="true"} ! (-)-secoisolariciresinol metabolic process
@@ -73743,6 +73759,7 @@
 id: GO:1902138 ! (-)-secoisolariciresinol biosynthetic process
 is_a: GO:0009807 {is_inferred="true"} ! lignan biosynthetic process
 is_a: GO:0034312 {is_inferred="true"} ! diol biosynthetic process
+is_a: GO:0046189 {is_inferred="true"} ! phenol-containing compound biosynthetic process
 is_a: GO:1902136 {is_inferred="true"} ! (-)-secoisolariciresinol metabolic process
 
 [Term]
@@ -75523,6 +75540,7 @@
 
 [Term]
 id: GO:1902520 ! response to doxorubicin
+is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
 is_a: GO:1901654 {is_inferred="true"} ! response to ketone
 is_a: GO:1903416 {is_inferred="true"} ! response to glycoside
 
------------------------------------------------------------------------
r36294 | termgenie | 2016-10-14 07:47:00 -0700 (Fri, 14 Oct 2016) | 3 lines

TermGenie commit for user: hbye reviewed by mec

changes in entailments

------------------------------------------------------------------------
r36294 | termgenie | 2016-10-14 07:47:00 -0700 (Fri, 14 Oct 2016) | 3 lines

TermGenie commit for user: hbye reviewed by mec

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36294)
+++ go_inferences.obo	(working copy)
@@ -71543,17 +71543,13 @@
 
 [Term]
 id: GO:1901720 ! negative regulation of NMS complex assembly involved in kinetochore assembly
-is_a: GO:0031333 {is_inferred="true"} ! negative regulation of protein complex assembly
 is_a: GO:1901719 {is_inferred="true"} ! regulation of NMS complex assembly involved in kinetochore assembly
-is_a: GO:1902116 {is_inferred="true"} ! negative regulation of organelle assembly
-is_a: GO:2001251 {is_inferred="true"} ! negative regulation of chromosome organization
+is_a: GO:1905560 {is_inferred="true"} ! negative regulation of kinetochore assembly
 
 [Term]
 id: GO:1901721 ! positive regulation of NMS complex assembly involved in kinetochore assembly
-is_a: GO:0031334 {is_inferred="true"} ! positive regulation of protein complex assembly
 is_a: GO:1901719 {is_inferred="true"} ! regulation of NMS complex assembly involved in kinetochore assembly
-is_a: GO:1902117 {is_inferred="true"} ! positive regulation of organelle assembly
-is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
+is_a: GO:1905561 {is_inferred="true"} ! positive regulation of kinetochore assembly
 
 [Term]
 id: GO:1901722 ! regulation of cell proliferation involved in kidney development
@@ -90273,6 +90269,41 @@
 is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
 
 [Term]
+id: GO:1905557 ! regulation of mitotic nuclear envelope disassembly
+is_a: GO:0007346 {is_inferred="true"} ! regulation of mitotic cell cycle
+is_a: GO:0010549 {is_inferred="true"} ! regulation of membrane disassembly
+is_a: GO:0010564 {is_inferred="true"} ! regulation of cell cycle process
+is_a: GO:1903353 {is_inferred="true"} ! regulation of nucleus organization
+
+[Term]
+id: GO:1905558 ! negative regulation of mitotic nuclear envelope disassembly
+is_a: GO:0010639 {is_inferred="true"} ! negative regulation of organelle organization
+is_a: GO:0010948 {is_inferred="true"} ! negative regulation of cell cycle process
+is_a: GO:0045930 {is_inferred="true"} ! negative regulation of mitotic cell cycle
+is_a: GO:1905557 {is_inferred="true"} ! regulation of mitotic nuclear envelope disassembly
+
+[Term]
+id: GO:1905559 ! positive regulation of mitotic nuclear envelope disassembly
+is_a: GO:0010638 {is_inferred="true"} ! positive regulation of organelle organization
+is_a: GO:0045931 {is_inferred="true"} ! positive regulation of mitotic cell cycle
+is_a: GO:0090068 {is_inferred="true"} ! positive regulation of cell cycle process
+is_a: GO:1905557 {is_inferred="true"} ! regulation of mitotic nuclear envelope disassembly
+
+[Term]
+id: GO:1905560 ! negative regulation of kinetochore assembly
+is_a: GO:0031333 {is_inferred="true"} ! negative regulation of protein complex assembly
+is_a: GO:0090234 {is_inferred="true"} ! regulation of kinetochore assembly
+is_a: GO:1902116 {is_inferred="true"} ! negative regulation of organelle assembly
+is_a: GO:2001251 {is_inferred="true"} ! negative regulation of chromosome organization
+
+[Term]
+id: GO:1905561 ! positive regulation of kinetochore assembly
+is_a: GO:0031334 {is_inferred="true"} ! positive regulation of protein complex assembly
+is_a: GO:0090234 {is_inferred="true"} ! regulation of kinetochore assembly
+is_a: GO:1902117 {is_inferred="true"} ! positive regulation of organelle assembly
+is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36291 | paola | 2016-10-14 07:40:00 -0700 (Fri, 14 Oct 2016) | 2 lines

NTR: mycelium reproductive competence #12660 - closed - added 'acquisition of mycelium reproductive competence'

changes in entailments

------------------------------------------------------------------------
r36289 | paola | 2016-10-14 07:04:54 -0700 (Fri, 14 Oct 2016) | 3 lines

NTR: mycelium reproductive competence #12660 - work in progress - edited GO:0010049 ‘acquisition of reproductive competence’ to refer to plants

changes in entailments

------------------------------------------------------------------------
r36287 | paola | 2016-10-14 06:04:28 -0700 (Fri, 14 Oct 2016) | 3 lines

GH NTR: aerial mycelium formation #12659 - work in progress - edited GO:0097736 ‘aerial mycelium formation’

changes in entailments

------------------------------------------------------------------------
r36285 | mcourtot | 2016-10-14 05:42:12 -0700 (Fri, 14 Oct 2016) | 1 line

added taxon restriction aand closed https://github.com/geneontology/go-ontology/issues/12728

changes in entailments

------------------------------------------------------------------------
r36283 | paola | 2016-10-14 05:30:27 -0700 (Fri, 14 Oct 2016) | 3 lines

GH NTR: aerial mycelium formation #12659 - work in progress - added GO:0097736 ‘aerial mycelium formation’

changes in entailments

------------------------------------------------------------------------
r36281 | mcourtot | 2016-10-14 05:16:35 -0700 (Fri, 14 Oct 2016) | 1 line

closed https://github.com/geneontology/go-ontology/issues/12494

changes in entailments

------------------------------------------------------------------------
r36279 | mcourtot | 2016-10-14 05:07:14 -0700 (Fri, 14 Oct 2016) | 1 line

added missing comment as per https://github.com/geneontology/go-ontology/issues/12728

changes in entailments

------------------------------------------------------------------------
r36277 | mcourtot | 2016-10-14 04:04:38 -0700 (Fri, 14 Oct 2016) | 1 line

fixed build, added GO_0101026, nuclear membrane biogenesis involved in mitotic nuclear division

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36277)
+++ go_inferences.obo	(working copy)
@@ -62694,6 +62694,10 @@
 is_a: GO:0001935 {is_inferred="true"} ! endothelial cell proliferation
 
 [Term]
+id: GO:0101024 ! nuclear membrane organization involved in mitotic nuclear division
+is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
+
+[Term]
 id: GO:1900000 ! regulation of anthocyanin catabolic process
 is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
 is_a: GO:0031537 {is_inferred="true"} ! regulation of anthocyanin metabolic process
------------------------------------------------------------------------
r36273 | mcourtot | 2016-10-14 03:02:57 -0700 (Fri, 14 Oct 2016) | 1 line

removed offending synonym on CL term

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36273)
+++ go_inferences.obo	(working copy)
@@ -62690,6 +62690,10 @@
 is_a: GO:0044452 {is_inferred="true"} ! nucleolar part
 
 [Term]
+id: GO:0101023 ! vascular endothelial cell proliferation
+is_a: GO:0001935 {is_inferred="true"} ! endothelial cell proliferation
+
+[Term]
 id: GO:1900000 ! regulation of anthocyanin catabolic process
 is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
 is_a: GO:0031537 {is_inferred="true"} ! regulation of anthocyanin metabolic process
------------------------------------------------------------------------
r36254 | termgenie | 2016-10-13 02:38:59 -0700 (Thu, 13 Oct 2016) | 2 lines

TermGenie commit for user: pr reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36254)
+++ go_inferences.obo	(working copy)
@@ -90260,6 +90260,11 @@
 is_a: GO:1905553 {is_inferred="true"} ! regulation of patterning of blood vessels
 
 [Term]
+id: GO:1905556 ! ciliary vesicle assembly
+is_a: GO:0016050 {is_inferred="true"} ! vesicle organization
+is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36252 | paola | 2016-10-13 02:06:04 -0700 (Thu, 13 Oct 2016) | 3 lines

GH NTRs/OTRs: New cilium assembly terms and references to Reactome IDs #12572 - work in progress - added has_part links between cilium types and outer/inner dynein arms as appropriate. Added ‘immotile’ synonyms to non-motile cilia types.

changes in entailments

------------------------------------------------------------------------
r36250 | termgenie | 2016-10-13 01:11:53 -0700 (Thu, 13 Oct 2016) | 4 lines

TermGenie commit for user: nc reviewed by mec

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36250)
+++ go_inferences.obo	(working copy)
@@ -54370,8 +54370,8 @@
 [Term]
 id: GO:0071413 ! cellular response to hydroxyisoflavone
 is_a: GO:0033594 {is_inferred="true"} ! response to hydroxyisoflavone
-is_a: GO:0071407 {is_inferred="true"} ! cellular response to organic cyclic compound
 is_a: GO:1901655 {is_inferred="true"} ! cellular response to ketone
+is_a: GO:1905546 {is_inferred="true"} ! cellular response to phenylpropanoid
 
 [Term]
 id: GO:0071414 ! cellular response to methotrexate
@@ -73861,9 +73861,9 @@
 
 [Term]
 id: GO:1902169 ! cellular response to catechin
-is_a: GO:0071407 {is_inferred="true"} ! cellular response to organic cyclic compound
 is_a: GO:1902168 {is_inferred="true"} ! response to catechin
 is_a: GO:1905396 {is_inferred="true"} ! cellular response to flavonoid
+is_a: GO:1905546 {is_inferred="true"} ! cellular response to phenylpropanoid
 
 [Term]
 id: GO:1902170 ! cellular response to reactive nitrogen species
@@ -90209,6 +90209,11 @@
 is_a: GO:1903813 {is_inferred="true"} ! L-methionine import into cell
 
 [Term]
+id: GO:1905546 ! cellular response to phenylpropanoid
+is_a: GO:0071407 {is_inferred="true"} ! cellular response to organic cyclic compound
+is_a: GO:0080184 {is_inferred="true"} ! response to phenylpropanoid
+
+[Term]
 id: GO:1905547 ! regulation of telomeric heterochromatin assembly
 is_a: GO:0031445 {is_inferred="true"} ! regulation of heterochromatin assembly
 
@@ -90237,6 +90242,24 @@
 is_a: GO:1905550 {is_inferred="true"} ! regulation of protein localization to endoplasmic reticulum
 
 [Term]
+id: GO:1905553 ! regulation of patterning of blood vessels
+is_a: GO:0045765 {is_inferred="true"} ! regulation of angiogenesis
+is_a: GO:0060688 {is_inferred="true"} ! regulation of morphogenesis of a branching structure
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
+
+[Term]
+id: GO:1905554 ! negative regulation of patterning of blood vessels
+is_a: GO:0016525 {is_inferred="true"} ! negative regulation of angiogenesis
+is_a: GO:1905331 {is_inferred="true"} ! negative regulation of morphogenesis of an epithelium
+is_a: GO:1905553 {is_inferred="true"} ! regulation of patterning of blood vessels
+
+[Term]
+id: GO:1905555 ! positive regulation of patterning of blood vessels
+is_a: GO:0045766 {is_inferred="true"} ! positive regulation of angiogenesis
+is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
+is_a: GO:1905553 {is_inferred="true"} ! regulation of patterning of blood vessels
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36247 | paola | 2016-10-13 00:25:24 -0700 (Thu, 13 Oct 2016) | 2 lines

Trying to fix broken build

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36247)
+++ go_inferences.obo	(working copy)
@@ -51305,10 +51305,6 @@
 is_a: GO:0048029 {is_inferred="true"} ! monosaccharide binding
 
 [Term]
-id: GO:0070062 ! extracellular exosome
-is_a: GO:1903561 {is_inferred="true"} ! extracellular vesicle
-
-[Term]
 id: GO:0070070 ! proton-transporting V-type ATPase complex assembly
 is_a: GO:0070071 {is_inferred="true"} ! proton-transporting two-sector ATPase complex assembly
 
------------------------------------------------------------------------
r36239 | davidos | 2016-10-12 08:30:42 -0700 (Wed, 12 Oct 2016) | 6 lines

* New term request for DIF dechlorinase activity #12692

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36239)
+++ go_inferences.obo	(working copy)
@@ -61126,6 +61126,7 @@
 
 [Term]
 id: GO:0098837 ! postsynaptic recycling endosome
+is_a: GO:0055037 {is_inferred="true"} ! recycling endosome
 is_a: GO:0098845 {is_inferred="true"} ! postsynaptic endosome
 
 [Term]
@@ -61705,6 +61706,10 @@
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
 
 [Term]
+id: GO:0099003 ! vesicle-mediated transport in synapse
+is_a: GO:0016192 {is_inferred="true"} ! vesicle-mediated transport
+
+[Term]
 id: GO:0099005 ! extrinsic component of postsynaptic recycling endosome membrane
 is_a: GO:0098999 {is_inferred="true"} ! extrinsic component of postsynaptic endosome membrane
 
@@ -61968,6 +61973,23 @@
 is_a: GO:0006996 {is_inferred="true"} ! organelle organization
 
 [Term]
+id: GO:0099087 ! anterograde axonal transport of messenger ribonucleoprotein complex
+is_a: GO:0008089 {is_inferred="true"} ! anterograde axonal transport
+is_a: GO:0099088 {is_inferred="true"} ! axonal transport of messenger ribonucleoprotein complex
+
+[Term]
+id: GO:0099088 ! axonal transport of messenger ribonucleoprotein complex
+is_a: GO:0098930 {is_inferred="true"} ! axonal transport
+
+[Term]
+id: GO:0099089 ! establishment of endoplasmic reticulum localization to postsynapse
+is_a: GO:0051686 {is_inferred="true"} ! establishment of ER localization
+
+[Term]
+id: GO:0099090 ! recycling endosome localization within postsynapse
+is_a: GO:0032439 {is_inferred="true"} ! endosome localization
+
+[Term]
 id: GO:0099400 ! caveola neck
 is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
 
@@ -85418,6 +85440,7 @@
 [Term]
 id: GO:1904564 ! Nbp35-Cfd1 ATPase complex
 is_a: GO:1904949 {is_inferred="true"} ! ATPase complex
+is_a: GO:1990229 {is_inferred="true"} ! iron-sulfur cluster assembly complex
 
 [Term]
 id: GO:1904565 ! response to 1-oleoyl-sn-glycerol 3-phosphate
@@ -90059,18 +90082,16 @@
 
 [Term]
 id: GO:1905518 ! regulation of presynaptic active zone assembly
-is_a: GO:0044087 {is_inferred="true"} ! regulation of cellular component biogenesis
-is_a: GO:0050807 {is_inferred="true"} ! regulation of synapse organization
+is_a: GO:0051963 {is_inferred="true"} ! regulation of synapse assembly
 
 [Term]
 id: GO:1905519 ! negative regulation of presynaptic active zone assembly
-is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
+is_a: GO:0051964 {is_inferred="true"} ! negative regulation of synapse assembly
 is_a: GO:1905518 {is_inferred="true"} ! regulation of presynaptic active zone assembly
 
 [Term]
 id: GO:1905520 ! positive regulation of presynaptic active zone assembly
-is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
-is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
+is_a: GO:0051965 {is_inferred="true"} ! positive regulation of synapse assembly
 is_a: GO:1905518 {is_inferred="true"} ! regulation of presynaptic active zone assembly
 
 [Term]
------------------------------------------------------------------------
r36237 | mcourtot | 2016-10-12 08:21:59 -0700 (Wed, 12 Oct 2016) | 1 line

removed equivalence axiom on GO:0070062 extracellular exosome

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36237)
+++ go_inferences.obo	(working copy)
@@ -28967,7 +28967,7 @@
 
 [Term]
 id: GO:0034774 ! secretory granule lumen
-is_a: GO:0060205 {is_inferred="true"} ! cytoplasmic membrane-bounded vesicle lumen
+is_a: GO:0060205 {is_inferred="true"} ! cytoplasmic vesicle lumen
 
 [Term]
 id: GO:0034775 ! glutathione transmembrane transport
@@ -33540,6 +33540,7 @@
 [Term]
 id: GO:0042996 ! regulation of Golgi to plasma membrane protein transport
 is_a: GO:0051223 {is_inferred="true"} ! regulation of protein transport
+is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
 is_a: GO:0090003 {is_inferred="true"} ! regulation of establishment of protein localization to plasma membrane
 
 [Term]
@@ -33560,6 +33561,7 @@
 
 [Term]
 id: GO:0043001 ! Golgi to plasma membrane protein transport
+is_a: GO:0006893 {is_inferred="true"} ! Golgi to plasma membrane transport
 is_a: GO:0015031 {is_inferred="true"} ! protein transport
 is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
 is_a: GO:0072659 {is_inferred="true"} ! protein localization to plasma membrane
@@ -35956,11 +35958,13 @@
 id: GO:0044861 ! protein transport into plasma membrane raft
 is_a: GO:0044860 {is_inferred="true"} ! protein localization to plasma membrane raft
 is_a: GO:0090002 {is_inferred="true"} ! establishment of protein localization to plasma membrane
+is_a: GO:0098876 {is_inferred="true"} ! vesicle-mediated transport to the plasma membrane
 
 [Term]
 id: GO:0044862 ! protein transport out of plasma membrane raft
 is_a: GO:0072657 {is_inferred="true"} ! protein localization to membrane
 is_a: GO:0090002 {is_inferred="true"} ! establishment of protein localization to plasma membrane
+is_a: GO:0098876 {is_inferred="true"} ! vesicle-mediated transport to the plasma membrane
 is_a: GO:0099632 {is_inferred="true"} ! protein transport within plasma membrane
 is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
 
@@ -47968,7 +47972,7 @@
 is_a: GO:0060194 {is_inferred="true"} ! regulation of antisense RNA transcription
 
 [Term]
-id: GO:0060205 ! cytoplasmic membrane-bounded vesicle lumen
+id: GO:0060205 ! cytoplasmic vesicle lumen
 is_a: GO:0070013 {is_inferred="true"} ! intracellular organelle lumen
 
 [Term]
@@ -51301,6 +51305,10 @@
 is_a: GO:0048029 {is_inferred="true"} ! monosaccharide binding
 
 [Term]
+id: GO:0070062 ! extracellular exosome
+is_a: GO:1903561 {is_inferred="true"} ! extracellular vesicle
+
+[Term]
 id: GO:0070070 ! proton-transporting V-type ATPase complex assembly
 is_a: GO:0070071 {is_inferred="true"} ! proton-transporting two-sector ATPase complex assembly
 
@@ -56478,6 +56486,7 @@
 
 [Term]
 id: GO:0072661 ! protein targeting to plasma membrane
+is_a: GO:0098876 {is_inferred="true"} ! vesicle-mediated transport to the plasma membrane
 is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
 
 [Term]
@@ -58350,6 +58359,7 @@
 
 [Term]
 id: GO:0090119 ! vesicle-mediated cholesterol transport
+is_a: GO:0016192 {is_inferred="true"} ! vesicle-mediated transport
 is_a: GO:0016482 {is_inferred="true"} ! cytosolic transport
 is_a: GO:0032367 {is_inferred="true"} ! intracellular cholesterol transport
 
@@ -61477,6 +61487,7 @@
 [Term]
 id: GO:0098943 ! neurotransmitter receptor transport, postsynaptic endosome to lysosome
 is_a: GO:0007041 {is_inferred="true"} ! lysosomal transport
+is_a: GO:0016192 {is_inferred="true"} ! vesicle-mediated transport
 is_a: GO:0016197 {is_inferred="true"} ! endosomal transport
 is_a: GO:0061462 {is_inferred="true"} ! protein localization to lysosome
 is_a: GO:0072666 {is_inferred="true"} ! establishment of protein localization to vacuole
@@ -61594,6 +61605,7 @@
 
 [Term]
 id: GO:0098968 ! neurotransmitter receptor transport postsynaptic membrane to endosome
+is_a: GO:0016192 {is_inferred="true"} ! vesicle-mediated transport
 is_a: GO:0016197 {is_inferred="true"} ! endosomal transport
 is_a: GO:0035418 {is_inferred="true"} ! protein localization to synapse
 is_a: GO:0072666 {is_inferred="true"} ! establishment of protein localization to vacuole
@@ -79902,6 +79914,7 @@
 id: GO:1903445 ! protein transport from ciliary membrane to plasma membrane
 is_a: GO:0032594 {is_inferred="true"} ! protein transport within lipid bilayer
 is_a: GO:0072657 {is_inferred="true"} ! protein localization to membrane
+is_a: GO:0098876 {is_inferred="true"} ! vesicle-mediated transport to the plasma membrane
 is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
 
 [Term]
@@ -86831,7 +86844,7 @@
 [Term]
 id: GO:1904856 ! cytolytic granule lumen
 is_a: GO:0005775 {is_inferred="true"} ! vacuolar lumen
-is_a: GO:0060205 {is_inferred="true"} ! cytoplasmic membrane-bounded vesicle lumen
+is_a: GO:0060205 {is_inferred="true"} ! cytoplasmic vesicle lumen
 
 [Term]
 id: GO:1904857 ! regulation of endothelial cell chemotaxis to vascular endothelial growth factor
------------------------------------------------------------------------
r36228 | termgenie | 2016-10-12 06:01:15 -0700 (Wed, 12 Oct 2016) | 2 lines

TermGenie commit for user: vw reviewed by mec

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36229)
+++ go_inferences.obo	(working copy)
@@ -90183,6 +90183,12 @@
 is_a: GO:0043235 {is_inferred="true"} ! receptor complex
 
 [Term]
+id: GO:1905544 ! L-methionine import across plasma membrane
+is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
+is_a: GO:1902475 {is_inferred="true"} ! L-alpha-amino acid transmembrane transport
+is_a: GO:1903813 {is_inferred="true"} ! L-methionine import into cell
+
+[Term]
 id: GO:1905547 ! regulation of telomeric heterochromatin assembly
 is_a: GO:0031445 {is_inferred="true"} ! regulation of heterochromatin assembly
 
------------------------------------------------------------------------
r36227 | termgenie | 2016-10-12 05:55:44 -0700 (Wed, 12 Oct 2016) | 4 lines

TermGenie commit for user: rz reviewed by mec

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36227)
+++ go_inferences.obo	(working copy)
@@ -90197,6 +90197,20 @@
 is_a: GO:1905547 {is_inferred="true"} ! regulation of telomeric heterochromatin assembly
 
 [Term]
+id: GO:1905550 ! regulation of protein localization to endoplasmic reticulum
+is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
+
+[Term]
+id: GO:1905551 ! negative regulation of protein localization to endoplasmic reticulum
+is_a: GO:1903828 {is_inferred="true"} ! negative regulation of cellular protein localization
+is_a: GO:1905550 {is_inferred="true"} ! regulation of protein localization to endoplasmic reticulum
+
+[Term]
+id: GO:1905552 ! positive regulation of protein localization to endoplasmic reticulum
+is_a: GO:1903829 {is_inferred="true"} ! positive regulation of cellular protein localization
+is_a: GO:1905550 {is_inferred="true"} ! regulation of protein localization to endoplasmic reticulum
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36223 | termgenie | 2016-10-12 05:41:52 -0700 (Wed, 12 Oct 2016) | 3 lines

TermGenie commit for user: nc reviewed by mec

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36224)
+++ go_inferences.obo	(working copy)
@@ -90183,6 +90183,20 @@
 is_a: GO:0043235 {is_inferred="true"} ! receptor complex
 
 [Term]
+id: GO:1905547 ! regulation of telomeric heterochromatin assembly
+is_a: GO:0031445 {is_inferred="true"} ! regulation of heterochromatin assembly
+
+[Term]
+id: GO:1905548 ! negative regulation of telomeric heterochromatin assembly
+is_a: GO:0031452 {is_inferred="true"} ! negative regulation of heterochromatin assembly
+is_a: GO:1905547 {is_inferred="true"} ! regulation of telomeric heterochromatin assembly
+
+[Term]
+id: GO:1905549 ! positive regulation of telomeric heterochromatin assembly
+is_a: GO:0031453 {is_inferred="true"} ! positive regulation of heterochromatin assembly
+is_a: GO:1905547 {is_inferred="true"} ! regulation of telomeric heterochromatin assembly
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36211 | mcourtot | 2016-10-11 06:52:02 -0700 (Tue, 11 Oct 2016) | 3 lines

removing extra [Term]

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36221)
+++ go_inferences.obo	(working copy)
@@ -35621,6 +35621,10 @@
 is_a: GO:0044464 {is_inferred="true"} ! cell part
 
 [Term]
+id: GO:0044458 ! motile cilium assembly
+is_a: GO:0042384 {is_inferred="true"} ! cilium assembly
+
+[Term]
 id: GO:0044459 ! plasma membrane part
 is_a: GO:0044425 {is_inferred="true"} ! membrane part
 is_a: GO:0044464 {is_inferred="true"} ! cell part
@@ -82068,10 +82072,6 @@
 is_a: GO:1903884 {is_inferred="true"} ! regulation of chemokine (C-C motif) ligand 20 production
 
 [Term]
-id: GO:0044458 ! motile cilium assembly
-is_a: GO:0042384 {is_inferred="true"} ! cilium assembly
-
-[Term]
 id: GO:1903888 ! regulation of plant epidermal cell differentiation
 is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
 
@@ -90154,10 +90154,35 @@
 is_a: GO:1905535 {is_inferred="true"} ! regulation of eukaryotic translation initiation factor 4F complex assembly
 
 [Term]
+id: GO:1905538 ! polysome binding
+is_a: GO:0043021 {is_inferred="true"} ! ribonucleoprotein complex binding
+
+[Term]
 id: GO:1905539 ! regulation of postsynapse to nucleus signaling pathway
 is_a: GO:0009966 {is_inferred="true"} ! regulation of signal transduction
 
 [Term]
+id: GO:1905540 ! interleukin-7 receptor complex
+is_a: GO:0043234 {is_inferred="true"} ! protein complex
+is_a: GO:0043235 {is_inferred="true"} ! receptor complex
+
+[Term]
+id: GO:1905541 ! regulation of L-arginine import across plasma membrane
+is_a: GO:1902826 {is_inferred="true"} ! regulation of L-arginine import into cell
+is_a: GO:1903789 {is_inferred="true"} ! regulation of amino acid transmembrane transport
+
+[Term]
+id: GO:1905542 ! negative regulation of L-arginine import across plasma membrane
+is_a: GO:0034763 {is_inferred="true"} ! negative regulation of transmembrane transport
+is_a: GO:1902827 {is_inferred="true"} ! negative regulation of L-arginine import into cell
+is_a: GO:1905541 {is_inferred="true"} ! regulation of L-arginine import across plasma membrane
+
+[Term]
+id: GO:1905543 ! interleukin-15 receptor complex
+is_a: GO:0043234 {is_inferred="true"} ! protein complex
+is_a: GO:0043235 {is_inferred="true"} ! receptor complex
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36163 | termgenie | 2016-10-07 10:10:06 -0700 (Fri, 07 Oct 2016) | 2 lines

TermGenie commit for user: dos reviewed by dos

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36163)
+++ go_inferences.obo	(working copy)
@@ -90154,6 +90154,10 @@
 is_a: GO:1905535 {is_inferred="true"} ! regulation of eukaryotic translation initiation factor 4F complex assembly
 
 [Term]
+id: GO:1905539 ! regulation of postsynapse to nucleus signaling pathway
+is_a: GO:0009966 {is_inferred="true"} ! regulation of signal transduction
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36159 | termgenie | 2016-10-07 06:47:22 -0700 (Fri, 07 Oct 2016) | 4 lines

TermGenie commit for user: bc reviewed by dph

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36159)
+++ go_inferences.obo	(working copy)
@@ -90140,6 +90140,20 @@
 is_a: GO:1905532 {is_inferred="true"} ! regulation of leucine import across plasma membrane
 
 [Term]
+id: GO:1905535 ! regulation of eukaryotic translation initiation factor 4F complex assembly
+is_a: GO:0043254 {is_inferred="true"} ! regulation of protein complex assembly
+
+[Term]
+id: GO:1905536 ! negative regulation of eukaryotic translation initiation factor 4F complex assembly
+is_a: GO:0031333 {is_inferred="true"} ! negative regulation of protein complex assembly
+is_a: GO:1905535 {is_inferred="true"} ! regulation of eukaryotic translation initiation factor 4F complex assembly
+
+[Term]
+id: GO:1905537 ! positive regulation of eukaryotic translation initiation factor 4F complex assembly
+is_a: GO:0031334 {is_inferred="true"} ! positive regulation of protein complex assembly
+is_a: GO:1905535 {is_inferred="true"} ! regulation of eukaryotic translation initiation factor 4F complex assembly
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36153 | dph | 2016-10-07 05:41:36 -0700 (Fri, 07 Oct 2016) | 2 lines

Tweaked the names of the laminin terms in accordance with GH12717. GH12717-closed.

changes in entailments

------------------------------------------------------------------------
r36149 | dph | 2016-10-06 13:03:11 -0700 (Thu, 06 Oct 2016) | 2 lines

Partially completed GH12717. Laminin synonyms.

changes in entailments

------------------------------------------------------------------------
r36146 | dph | 2016-10-06 12:21:53 -0700 (Thu, 06 Oct 2016) | 2 lines

Fixed bad xrefs.

changes in entailments

------------------------------------------------------------------------
r36142 | dph | 2016-10-06 11:23:33 -0700 (Thu, 06 Oct 2016) | 2 lines

Obsoleted GO:0061597. This was supposed to be done on June 15, 2016. The notice was sent on May 31. This is part of GH12443.

changes in entailments

------------------------------------------------------------------------
r36140 | dph | 2016-10-06 08:32:12 -0700 (Thu, 06 Oct 2016) | 2 lines

GH12702-closed

changes in entailments

------------------------------------------------------------------------
r36128 | dph | 2016-10-06 07:02:59 -0700 (Thu, 06 Oct 2016) | 2 lines

GH12715-closed

changes in entailments

------------------------------------------------------------------------
r36126 | termgenie | 2016-10-06 06:21:23 -0700 (Thu, 06 Oct 2016) | 4 lines

TermGenie commit for user: vw reviewed by dph

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36126)
+++ go_inferences.obo	(working copy)
@@ -90109,6 +90109,37 @@
 is_a: GO:1905526 {is_inferred="true"} ! regulation of Golgi lumen acidification
 
 [Term]
+id: GO:1905529 ! regulation of uracil import across plasma membrane
+is_a: GO:0034762 {is_inferred="true"} ! regulation of transmembrane transport
+
+[Term]
+id: GO:1905530 ! negative regulation of uracil import across plasma membrane
+is_a: GO:0034763 {is_inferred="true"} ! negative regulation of transmembrane transport
+is_a: GO:1905529 {is_inferred="true"} ! regulation of uracil import across plasma membrane
+
+[Term]
+id: GO:1905531 ! positive regulation of uracil import across plasma membrane
+is_a: GO:0034764 {is_inferred="true"} ! positive regulation of transmembrane transport
+is_a: GO:1905529 {is_inferred="true"} ! regulation of uracil import across plasma membrane
+
+[Term]
+id: GO:1905532 ! regulation of leucine import across plasma membrane
+is_a: GO:1903128 {is_inferred="true"} ! regulation of leucine import into cell
+is_a: GO:1903789 {is_inferred="true"} ! regulation of amino acid transmembrane transport
+
+[Term]
+id: GO:1905533 ! negative regulation of leucine import across plasma membrane
+is_a: GO:0034763 {is_inferred="true"} ! negative regulation of transmembrane transport
+is_a: GO:1903129 {is_inferred="true"} ! negative regulation of leucine import into cell
+is_a: GO:1905532 {is_inferred="true"} ! regulation of leucine import across plasma membrane
+
+[Term]
+id: GO:1905534 ! positive regulation of leucine import across plasma membrane
+is_a: GO:0034764 {is_inferred="true"} ! positive regulation of transmembrane transport
+is_a: GO:1903130 {is_inferred="true"} ! positive regulation of leucine import into cell
+is_a: GO:1905532 {is_inferred="true"} ! regulation of leucine import across plasma membrane
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36122 | dph | 2016-10-06 04:26:53 -0700 (Thu, 06 Oct 2016) | 2 lines

GH12713-closed

changes in entailments

------------------------------------------------------------------------
r36121 | dph | 2016-10-06 04:23:08 -0700 (Thu, 06 Oct 2016) | 2 lines

GH12706-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36121)
+++ go_inferences.obo	(working copy)
@@ -4850,6 +4850,18 @@
 is_a: GO:0019966 {is_inferred="true"} ! interleukin-1 binding
 
 [Term]
+id: GO:0005224 ! ATP-binding and phosphorylation-dependent chloride channel activity
+is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
+
+[Term]
+id: GO:0005229 ! intracellular calcium activated chloride channel activity
+is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
+
+[Term]
+id: GO:0005247 ! voltage-gated chloride channel activity
+is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
+
+[Term]
 id: GO:0005274 ! allantoin uptake transmembrane transporter activity
 is_a: GO:0015563 {is_inferred="true"} ! uptake transmembrane transporter activity
 is_a: GO:0042887 {is_inferred="true"} ! amide transmembrane transporter activity
@@ -8720,6 +8732,10 @@
 is_a: GO:0007423 {is_inferred="true"} ! sensory organ development
 
 [Term]
+id: GO:0008068 ! extracellular-glutamate-gated chloride channel activity
+is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
+
+[Term]
 id: GO:0008069 ! dorsal/ventral axis specification, ovarian follicular epithelium
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
@@ -17053,6 +17069,10 @@
 is_a: GO:0005501 {is_inferred="true"} ! retinoid binding
 
 [Term]
+id: GO:0016934 ! extracellular-glycine-gated chloride channel activity
+is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
+
+[Term]
 id: GO:0017015 ! regulation of transforming growth factor beta receptor signaling pathway
 is_a: GO:0090092 {is_inferred="true"} ! regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
 is_a: GO:1903844 {is_inferred="true"} ! regulation of cellular response to transforming growth factor beta stimulus
@@ -17744,6 +17764,10 @@
 is_a: GO:0000166 {is_inferred="true"} ! nucleotide binding
 
 [Term]
+id: GO:0019182 ! histamine-gated chloride channel activity
+is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
+
+[Term]
 id: GO:0019183 ! histamine-gated chloride channel complex
 is_a: GO:0098802 {is_inferred="true"} ! plasma membrane receptor complex
 
@@ -20021,12 +20045,12 @@
 
 [Term]
 id: GO:0022851 ! GABA-gated chloride ion channel activity
-is_a: GO:0005254 {is_inferred="true"} ! chloride channel activity
 is_a: GO:0016917 {is_inferred="true"} ! GABA receptor activity
+is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
 
 [Term]
 id: GO:0022852 ! glycine-gated chloride ion channel activity
-is_a: GO:0005254 {is_inferred="true"} ! chloride channel activity
+is_a: GO:0061797 {is_inferred="true"} ! pH-gated chloride channel activity
 
 [Term]
 id: GO:0022885 ! bacteriocin transmembrane transporter activity
@@ -51187,6 +51211,10 @@
 is_a: GO:1902410 {is_inferred="true"} ! mitotic cytokinetic process
 
 [Term]
+id: GO:0061797 ! pH-gated chloride channel activity
+is_a: GO:0005254 {is_inferred="true"} ! chloride channel activity
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
------------------------------------------------------------------------
r36103 | tberardi | 2016-10-05 12:54:13 -0700 (Wed, 05 Oct 2016) | 1 line

GH12578 spore-bearing organs should not be classified as animal organs - finally closed, added terms, cleaned up existing term names and relationships

changes in entailments

------------------------------------------------------------------------
r36101 | dph | 2016-10-05 09:28:06 -0700 (Wed, 05 Oct 2016) | 2 lines

GH12704-closed

changes in entailments

------------------------------------------------------------------------
r36099 | dph | 2016-10-05 09:10:05 -0700 (Wed, 05 Oct 2016) | 2 lines

GH12705-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36099)
+++ go_inferences.obo	(working copy)
@@ -51183,6 +51183,10 @@
 is_a: GO:0048837 {is_inferred="true"} ! sorus development
 
 [Term]
+id: GO:0061796 ! membrane addition at site of mitotic cytokinesis
+is_a: GO:1902410 {is_inferred="true"} ! mitotic cytokinetic process
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
------------------------------------------------------------------------
r36097 | dph | 2016-10-05 08:57:17 -0700 (Wed, 05 Oct 2016) | 2 lines

GH12712-closed

changes in entailments

------------------------------------------------------------------------
r36093 | termgenie | 2016-10-05 06:22:19 -0700 (Wed, 05 Oct 2016) | 4 lines

TermGenie commit for user: dph reviewed by dph

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 36093)
+++ go_inferences.obo	(working copy)
@@ -13009,16 +13009,19 @@
 [Term]
 id: GO:0010758 ! regulation of macrophage chemotaxis
 is_a: GO:0002688 {is_inferred="true"} ! regulation of leukocyte chemotaxis
+is_a: GO:1905521 {is_inferred="true"} ! regulation of macrophage migration
 
 [Term]
 id: GO:0010759 ! positive regulation of macrophage chemotaxis
 is_a: GO:0002690 {is_inferred="true"} ! positive regulation of leukocyte chemotaxis
 is_a: GO:0010758 {is_inferred="true"} ! regulation of macrophage chemotaxis
+is_a: GO:1905523 {is_inferred="true"} ! positive regulation of macrophage migration
 
 [Term]
 id: GO:0010760 ! negative regulation of macrophage chemotaxis
 is_a: GO:0002689 {is_inferred="true"} ! negative regulation of leukocyte chemotaxis
 is_a: GO:0010758 {is_inferred="true"} ! regulation of macrophage chemotaxis
+is_a: GO:1905522 {is_inferred="true"} ! negative regulation of macrophage migration
 
 [Term]
 id: GO:0010762 ! regulation of fibroblast migration
@@ -83273,20 +83276,20 @@
 
 [Term]
 id: GO:1904139 ! regulation of microglial cell migration
-is_a: GO:0002685 {is_inferred="true"} ! regulation of leukocyte migration
 is_a: GO:1903975 {is_inferred="true"} ! regulation of glial cell migration
+is_a: GO:1905521 {is_inferred="true"} ! regulation of macrophage migration
 
 [Term]
 id: GO:1904140 ! negative regulation of microglial cell migration
-is_a: GO:0002686 {is_inferred="true"} ! negative regulation of leukocyte migration
 is_a: GO:1903976 {is_inferred="true"} ! negative regulation of glial cell migration
 is_a: GO:1904139 {is_inferred="true"} ! regulation of microglial cell migration
+is_a: GO:1905522 {is_inferred="true"} ! negative regulation of macrophage migration
 
 [Term]
 id: GO:1904141 ! positive regulation of microglial cell migration
-is_a: GO:0002687 {is_inferred="true"} ! positive regulation of leukocyte migration
 is_a: GO:1903977 {is_inferred="true"} ! positive regulation of glial cell migration
 is_a: GO:1904139 {is_inferred="true"} ! regulation of microglial cell migration
+is_a: GO:1905523 {is_inferred="true"} ! positive regulation of macrophage migration
 
 [Term]
 id: GO:1904142 ! negative regulation of carotenoid biosynthetic process
@@ -90036,6 +90039,44 @@
 is_a: GO:1905518 {is_inferred="true"} ! regulation of presynaptic active zone assembly
 
 [Term]
+id: GO:1905521 ! regulation of macrophage migration
+is_a: GO:0002685 {is_inferred="true"} ! regulation of leukocyte migration
+
+[Term]
+id: GO:1905522 ! negative regulation of macrophage migration
+is_a: GO:0002686 {is_inferred="true"} ! negative regulation of leukocyte migration
+is_a: GO:1905521 {is_inferred="true"} ! regulation of macrophage migration
+
+[Term]
+id: GO:1905523 ! positive regulation of macrophage migration
+is_a: GO:0002687 {is_inferred="true"} ! positive regulation of leukocyte migration
+is_a: GO:1905521 {is_inferred="true"} ! regulation of macrophage migration
+
+[Term]
+id: GO:1905524 ! negative regulation of protein autoubiquitination
+is_a: GO:0031397 {is_inferred="true"} ! negative regulation of protein ubiquitination
+is_a: GO:1902498 {is_inferred="true"} ! regulation of protein autoubiquitination
+
+[Term]
+id: GO:1905525 ! regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron
+is_a: GO:0034396 {is_inferred="true"} ! negative regulation of transcription from RNA polymerase II promoter in response to iron
+is_a: GO:1900704 {is_inferred="true"} ! regulation of siderophore biosynthetic process
+
+[Term]
+id: GO:1905526 ! regulation of Golgi lumen acidification
+is_a: GO:0032847 {is_inferred="true"} ! regulation of cellular pH reduction
+
+[Term]
+id: GO:1905527 ! negative regulation of Golgi lumen acidification
+is_a: GO:0032848 {is_inferred="true"} ! negative regulation of cellular pH reduction
+is_a: GO:1905526 {is_inferred="true"} ! regulation of Golgi lumen acidification
+
+[Term]
+id: GO:1905528 ! positive regulation of Golgi lumen acidification
+is_a: GO:0032849 {is_inferred="true"} ! positive regulation of cellular pH reduction
+is_a: GO:1905526 {is_inferred="true"} ! regulation of Golgi lumen acidification
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r36087 | paola | 2016-10-05 05:59:03 -0700 (Wed, 05 Oct 2016) | 3 lines

GH Cellular component assembly/disassembly - add missing logical definitions #12232 - work in progress - added GO:0097735 ’DIM/DIP cell wall layer’; added logical def to ‘DIM/DIP cell wall layer assembly’

changes in entailments

------------------------------------------------------------------------
r36082 | dph | 2016-10-05 05:51:39 -0700 (Wed, 05 Oct 2016) | 2 lines

dded root term for GH12710, Golgi lumen acidification.

changes in entailments

------------------------------------------------------------------------
r36080 | dph | 2016-10-05 05:35:30 -0700 (Wed, 05 Oct 2016) | 2 lines

Added PMID to support last change.

changes in entailments

------------------------------------------------------------------------
r36022 | paola | 2016-10-05 01:23:45 -0700 (Wed, 05 Oct 2016) | 2 lines

GH NTR/OTR: multiciliation-related classes #12672 - work in progress - added taxon rules to 'blepharoplast'

changes in entailments

------------------------------------------------------------------------
r35992 | dph | 2016-10-04 09:43:22 -0700 (Tue, 04 Oct 2016) | 2 lines

Moved fibril to be an is_a child of supramolecular fiber. Made microfibril an extracellular matrix component and retained its fibril parent. Part of the plan outlined in GH125640.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35992)
+++ go_inferences.obo	(working copy)
@@ -33856,6 +33856,10 @@
 is_a: GO:0043200 {is_inferred="true"} ! response to amino acid
 
 [Term]
+id: GO:0043205 ! fibril
+is_a: GO:0044420 {is_inferred="true"} ! extracellular matrix component
+
+[Term]
 id: GO:0043208 ! glycosphingolipid binding
 is_a: GO:0046625 {is_inferred="true"} ! sphingolipid binding
 is_a: GO:0051861 {is_inferred="true"} ! glycolipid binding
------------------------------------------------------------------------
r35990 | paola | 2016-10-04 08:03:50 -0700 (Tue, 04 Oct 2016) | 3 lines

GH Cellular component assembly/disassembly - add missing logical definitions #12232 - work in progress - added logical def for ‘mitochondrion disassembly’

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35990)
+++ go_inferences.obo	(working copy)
@@ -665,10 +665,6 @@
 is_a: GO:0031062 {is_inferred="true"} ! positive regulation of histone methylation
 
 [Term]
-id: GO:0000422 ! mitophagy
-is_a: GO:0007005 {is_inferred="true"} ! mitochondrion organization
-
-[Term]
 id: GO:0000427 ! plastid-encoded plastid RNA polymerase complex
 is_a: GO:0000428 {is_inferred="true"} ! DNA-directed RNA polymerase complex
 is_a: GO:0044435 {is_inferred="true"} ! plastid part
@@ -51110,6 +51106,10 @@
 is_a: GO:0044712 {is_inferred="true"} ! single-organism catabolic process
 
 [Term]
+id: GO:0061726 ! mitochondrion disassembly
+is_a: GO:0007005 {is_inferred="true"} ! mitochondrion organization
+
+[Term]
 id: GO:0061727 ! methylglyoxal catabolic process to lactate
 is_a: GO:0006089 {is_inferred="true"} ! lactate metabolic process
 
------------------------------------------------------------------------
r35983 | paola | 2016-10-04 01:04:16 -0700 (Tue, 04 Oct 2016) | 3 lines

GH OTR: Align GO and Reactome on ciliary processes #12487 - work in progress - added link ‘ciliary receptor clustering involved in smoothened signaling pathway’ occurs_in ‘cilium’

changes in entailments

------------------------------------------------------------------------
r35975 | davidos | 2016-10-03 07:15:58 -0700 (Mon, 03 Oct 2016) | 1 line

Fixed: MP GO:0034638 phosphatidylcholine catabolic process #12696

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35975)
+++ go_inferences.obo	(working copy)
@@ -7288,7 +7288,7 @@
 
 [Term]
 id: GO:0006653 ! 1,2-diacyl-sn-glycero-3-phosphocholine metabolic process
-is_a: GO:0046470 {is_inferred="true"} ! phosphatidylcholine metabolic process
+is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
 
 [Term]
 id: GO:0006654 ! phosphatidic acid biosynthetic process
@@ -7302,10 +7302,15 @@
 
 [Term]
 id: GO:0006656 ! phosphatidylcholine biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
 is_a: GO:0046470 {is_inferred="true"} ! phosphatidylcholine metabolic process
+is_a: GO:0046474 {is_inferred="true"} ! glycerophospholipid biosynthetic process
+is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
 
 [Term]
+id: GO:0006657 ! CDP-choline pathway
+is_a: GO:0006656 {is_inferred="true"} ! phosphatidylcholine biosynthetic process
+
+[Term]
 id: GO:0006658 ! phosphatidylserine metabolic process
 is_a: GO:0006575 {is_inferred="true"} ! cellular modified amino acid metabolic process
 is_a: GO:0006650 {is_inferred="true"} ! glycerophospholipid metabolic process
@@ -9015,7 +9020,7 @@
 
 [Term]
 id: GO:0008525 ! phosphatidylcholine transporter activity
-is_a: GO:0005215 {is_inferred="true"} ! transporter activity
+is_a: GO:0005548 {is_inferred="true"} ! phospholipid transporter activity
 
 [Term]
 id: GO:0008526 ! phosphatidylinositol transporter activity
@@ -13504,14 +13509,16 @@
 
 [Term]
 id: GO:0010899 ! regulation of phosphatidylcholine catabolic process
-is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
 is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
+is_a: GO:0060696 {is_inferred="true"} ! regulation of phospholipid catabolic process
 
 [Term]
 id: GO:0010900 ! negative regulation of phosphatidylcholine catabolic process
-is_a: GO:0009895 {is_inferred="true"} ! negative regulation of catabolic process
 is_a: GO:0010899 {is_inferred="true"} ! regulation of phosphatidylcholine catabolic process
+is_a: GO:0031330 {is_inferred="true"} ! negative regulation of cellular catabolic process
+is_a: GO:0050995 {is_inferred="true"} ! negative regulation of lipid catabolic process
 is_a: GO:0051172 {is_inferred="true"} ! negative regulation of nitrogen compound metabolic process
+is_a: GO:1903726 {is_inferred="true"} ! negative regulation of phospholipid metabolic process
 
 [Term]
 id: GO:0010901 ! regulation of very-low-density lipoprotein particle remodeling
@@ -21860,6 +21867,8 @@
 
 [Term]
 id: GO:0031210 ! phosphatidylcholine binding
+is_a: GO:0005543 {is_inferred="true"} ! phospholipid binding
+is_a: GO:0050997 {is_inferred="true"} ! quaternary ammonium group binding
 is_a: GO:0070405 {is_inferred="true"} ! ammonium ion binding
 
 [Term]
@@ -28765,8 +28774,9 @@
 
 [Term]
 id: GO:0034638 ! phosphatidylcholine catabolic process
-is_a: GO:0009056 {is_inferred="true"} ! catabolic process
 is_a: GO:0046470 {is_inferred="true"} ! phosphatidylcholine metabolic process
+is_a: GO:0046475 {is_inferred="true"} ! glycerophospholipid catabolic process
+is_a: GO:1901565 {is_inferred="true"} ! organonitrogen compound catabolic process
 
 [Term]
 id: GO:0034639 ! L-amino acid efflux transmembrane transporter activity
@@ -41026,7 +41036,9 @@
 
 [Term]
 id: GO:0046470 ! phosphatidylcholine metabolic process
+is_a: GO:0006650 {is_inferred="true"} ! glycerophospholipid metabolic process
 is_a: GO:0097164 {is_inferred="true"} ! ammonium ion metabolic process
+is_a: GO:1901564 {is_inferred="true"} ! organonitrogen compound metabolic process
 
 [Term]
 id: GO:0046471 ! phosphatidylglycerol metabolic process
@@ -52822,20 +52834,14 @@
 [Term]
 id: GO:0070832 ! phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline
 is_a: GO:0006656 {is_inferred="true"} ! phosphatidylcholine biosynthetic process
-is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
 
 [Term]
 id: GO:0070833 ! phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine
 is_a: GO:0006656 {is_inferred="true"} ! phosphatidylcholine biosynthetic process
-is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
 
 [Term]
 id: GO:0070834 ! phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine
 is_a: GO:0006656 {is_inferred="true"} ! phosphatidylcholine biosynthetic process
-is_a: GO:0006793 {is_inferred="true"} ! phosphorus metabolic process
-is_a: GO:0071704 {is_inferred="true"} ! organic substance metabolic process
 
 [Term]
 id: GO:0070836 ! caveola assembly
@@ -62503,7 +62509,7 @@
 
 [Term]
 id: GO:0100048 ! positive regulation of phosphatidylcholine biosynthetic process by transcription from RNA polymerase II promoter
-is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
+is_a: GO:0100032 {is_inferred="true"} ! positive regulation of phospholipid biosynthetic process by transcription from RNA polymerase II promoter
 is_a: GO:2001247 {is_inferred="true"} ! positive regulation of phosphatidylcholine biosynthetic process
 
 [Term]
@@ -64965,7 +64971,7 @@
 
 [Term]
 id: GO:1900472 ! positive regulation of phosphatidylcholine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter
-is_a: GO:0045944 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter
+is_a: GO:1900413 {is_inferred="true"} ! positive regulation of phospholipid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter
 is_a: GO:2001247 {is_inferred="true"} ! positive regulation of phosphatidylcholine biosynthetic process
 
 [Term]
@@ -97346,19 +97352,19 @@
 
 [Term]
 id: GO:2001245 ! regulation of phosphatidylcholine biosynthetic process
-is_a: GO:0009889 {is_inferred="true"} ! regulation of biosynthetic process
 is_a: GO:0051171 {is_inferred="true"} ! regulation of nitrogen compound metabolic process
+is_a: GO:0071071 {is_inferred="true"} ! regulation of phospholipid biosynthetic process
 
 [Term]
 id: GO:2001246 ! negative regulation of phosphatidylcholine biosynthetic process
-is_a: GO:0009890 {is_inferred="true"} ! negative regulation of biosynthetic process
 is_a: GO:0051172 {is_inferred="true"} ! negative regulation of nitrogen compound metabolic process
+is_a: GO:0071072 {is_inferred="true"} ! negative regulation of phospholipid biosynthetic process
 is_a: GO:2001245 {is_inferred="true"} ! regulation of phosphatidylcholine biosynthetic process
 
 [Term]
 id: GO:2001247 ! positive regulation of phosphatidylcholine biosynthetic process
-is_a: GO:0009891 {is_inferred="true"} ! positive regulation of biosynthetic process
 is_a: GO:0051173 {is_inferred="true"} ! positive regulation of nitrogen compound metabolic process
+is_a: GO:0071073 {is_inferred="true"} ! positive regulation of phospholipid biosynthetic process
 is_a: GO:2001245 {is_inferred="true"} ! regulation of phosphatidylcholine biosynthetic process
 
 [Term]
------------------------------------------------------------------------
r35973 | davidos | 2016-10-03 06:25:31 -0700 (Mon, 03 Oct 2016) | 1 line

Fixed named equivalent class issue

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35973)
+++ go_inferences.obo	(working copy)
@@ -297,8 +297,8 @@
 
 [Term]
 id: GO:0000136 ! alpha-1,6-mannosyltransferase complex
+is_a: GO:0044425 {is_inferred="true"} ! membrane part
 is_a: GO:0044431 {is_inferred="true"} ! Golgi apparatus part
-is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 
 [Term]
 id: GO:0000142 ! cellular bud neck contractile ring
@@ -319,7 +319,6 @@
 
 [Term]
 id: GO:0000148 ! 1,3-beta-D-glucan synthase complex
-is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 is_a: GO:1990234 {is_inferred="true"} ! transferase complex
 
 [Term]
@@ -367,6 +366,10 @@
 is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
 
 [Term]
+id: GO:0000172 ! ribonuclease MRP complex
+is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
+
+[Term]
 id: GO:0000173 ! inactivation of MAPK activity involved in osmosensory signaling pathway
 is_a: GO:0047484 {is_inferred="true"} ! regulation of response to osmotic stress
 is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
@@ -427,7 +430,6 @@
 [Term]
 id: GO:0000214 ! tRNA-intron endonuclease complex
 is_a: GO:1902555 {is_inferred="true"} ! endoribonuclease complex
-is_a: GO:1905348 {is_inferred="true"} ! endonuclease complex
 
 [Term]
 id: GO:0000220 ! vacuolar proton-transporting V-type ATPase, V0 domain
@@ -620,6 +622,10 @@
 is_a: GO:0098852 {is_inferred="true"} ! lytic vacuole membrane
 
 [Term]
+id: GO:0000333 ! telomerase catalytic core complex
+is_a: GO:0042575 {is_inferred="true"} ! DNA polymerase complex
+
+[Term]
 id: GO:0000335 ! negative regulation of transposition, DNA-mediated
 is_a: GO:0000337 {is_inferred="true"} ! regulation of transposition, DNA-mediated
 is_a: GO:0010529 {is_inferred="true"} ! negative regulation of transposition
@@ -949,8 +955,8 @@
 [Term]
 id: GO:0000835 ! ER ubiquitin ligase complex
 is_a: GO:0000153 {is_inferred="true"} ! cytoplasmic ubiquitin ligase complex
+is_a: GO:0044425 {is_inferred="true"} ! membrane part
 is_a: GO:0044432 {is_inferred="true"} ! endoplasmic reticulum part
-is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 
 [Term]
 id: GO:0000902 ! cell morphogenesis
@@ -1229,10 +1235,6 @@
 is_a: GO:0046457 {is_inferred="true"} ! prostanoid biosynthetic process
 
 [Term]
-id: GO:0001518 ! voltage-gated sodium channel complex
-is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
-
-[Term]
 id: GO:0001520 ! outer dense fiber
 is_a: GO:0097223 {is_inferred="true"} ! sperm part
 
@@ -2045,7 +2047,7 @@
 
 [Term]
 id: GO:0002169 ! 3-methylcrotonyl-CoA carboxylase complex, mitochondrial
-is_a: GO:0098798 {is_inferred="true"} ! mitochondrial protein complex
+is_a: GO:0044429 {is_inferred="true"} ! mitochondrial part
 is_a: GO:1905202 {is_inferred="true"} ! methylcrotonoyl-CoA carboxylase complex
 
 [Term]
@@ -2062,7 +2064,6 @@
 
 [Term]
 id: GO:0002180 ! 5-lipoxygenase complex
-is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 is_a: GO:1990204 {is_inferred="true"} ! oxidoreductase complex
 
 [Term]
@@ -2077,7 +2078,7 @@
 [Term]
 id: GO:0002187 ! mitochondrial creatine kinase complex
 is_a: GO:0002185 {is_inferred="true"} ! creatine kinase complex
-is_a: GO:0098798 {is_inferred="true"} ! mitochondrial protein complex
+is_a: GO:0044429 {is_inferred="true"} ! mitochondrial part
 
 [Term]
 id: GO:0002189 ! ribose phosphate diphosphokinase complex
@@ -5286,10 +5287,6 @@
 is_a: GO:0098798 {is_inferred="true"} ! mitochondrial protein complex
 
 [Term]
-id: GO:0005760 ! gamma DNA polymerase complex
-is_a: GO:0098798 {is_inferred="true"} ! mitochondrial protein complex
-
-[Term]
 id: GO:0005761 ! mitochondrial ribosome
 is_a: GO:0000313 {is_inferred="true"} ! organellar ribosome
 is_a: GO:0044429 {is_inferred="true"} ! mitochondrial part
@@ -5416,18 +5413,12 @@
 [Term]
 id: GO:0005889 ! hydrogen:potassium-exchanging ATPase complex
 is_a: GO:0090533 {is_inferred="true"} ! cation-transporting ATPase complex
-is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
 [Term]
 id: GO:0005890 ! sodium:potassium-exchanging ATPase complex
 is_a: GO:0090533 {is_inferred="true"} ! cation-transporting ATPase complex
-is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
 [Term]
-id: GO:0005891 ! voltage-gated calcium channel complex
-is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
-
-[Term]
 id: GO:0005892 ! acetylcholine-gated channel complex
 is_a: GO:0098802 {is_inferred="true"} ! plasma membrane receptor complex
 
@@ -5486,8 +5477,8 @@
 
 [Term]
 id: GO:0005942 ! phosphatidylinositol 3-kinase complex
+is_a: GO:0044425 {is_inferred="true"} ! membrane part
 is_a: GO:0061695 {is_inferred="true"} ! transferase complex, transferring phosphorus-containing groups
-is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 
 [Term]
 id: GO:0005945 ! 6-phosphofructokinase complex
@@ -5545,8 +5536,8 @@
 
 [Term]
 id: GO:0005967 ! mitochondrial pyruvate dehydrogenase complex
+is_a: GO:0044429 {is_inferred="true"} ! mitochondrial part
 is_a: GO:0045254 {is_inferred="true"} ! pyruvate dehydrogenase complex
-is_a: GO:0098798 {is_inferred="true"} ! mitochondrial protein complex
 
 [Term]
 id: GO:0005968 ! Rab-protein geranylgeranyltransferase complex
@@ -6655,13 +6646,11 @@
 
 [Term]
 id: GO:0006334 ! nucleosome assembly
-is_a: GO:0006461 {is_inferred="true"} ! protein complex assembly
 is_a: GO:0065004 {is_inferred="true"} ! protein-DNA complex assembly
 
 [Term]
 id: GO:0006337 ! nucleosome disassembly
 is_a: GO:0032986 {is_inferred="true"} ! protein-DNA complex disassembly
-is_a: GO:0043241 {is_inferred="true"} ! protein complex disassembly
 
 [Term]
 id: GO:0006342 ! chromatin silencing
@@ -8735,10 +8724,6 @@
 is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
-id: GO:0008076 ! voltage-gated potassium channel complex
-is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
-
-[Term]
 id: GO:0008086 ! light-activated voltage-gated calcium channel activity
 is_a: GO:0004871 {is_inferred="true"} ! signal transducer activity
 
@@ -8839,7 +8824,6 @@
 
 [Term]
 id: GO:0008250 ! oligosaccharyltransferase complex
-is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 is_a: GO:1990234 {is_inferred="true"} ! transferase complex
 
 [Term]
@@ -8921,6 +8905,7 @@
 [Term]
 id: GO:0008305 ! integrin complex
 is_a: GO:0098636 {is_inferred="true"} ! protein complex involved in cell adhesion
+is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 is_a: GO:0098802 {is_inferred="true"} ! plasma membrane receptor complex
 
 [Term]
@@ -10234,7 +10219,6 @@
 
 [Term]
 id: GO:0009324 ! D-amino-acid dehydrogenase complex
-is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 is_a: GO:1990204 {is_inferred="true"} ! oxidoreductase complex
 
 [Term]
@@ -10539,7 +10523,6 @@
 [Term]
 id: GO:0009654 ! photosystem II oxygen evolving complex
 is_a: GO:0044436 {is_inferred="true"} ! thylakoid part
-is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 is_a: GO:1990204 {is_inferred="true"} ! oxidoreductase complex
 
 [Term]
@@ -11083,7 +11066,6 @@
 
 [Term]
 id: GO:0009923 ! fatty acid elongase complex
-is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 is_a: GO:1990234 {is_inferred="true"} ! transferase complex
 
 [Term]
@@ -17011,7 +16993,7 @@
 [Term]
 id: GO:0016507 ! mitochondrial fatty acid beta-oxidation multienzyme complex
 is_a: GO:0036125 {is_inferred="true"} ! fatty acid beta-oxidation multienzyme complex
-is_a: GO:0098798 {is_inferred="true"} ! mitochondrial protein complex
+is_a: GO:0044429 {is_inferred="true"} ! mitochondrial part
 
 [Term]
 id: GO:0016516 ! interleukin-4 receptor complex
@@ -17023,6 +17005,10 @@
 is_a: GO:2000181 {is_inferred="true"} ! negative regulation of blood vessel morphogenesis
 
 [Term]
+id: GO:0016533 ! cyclin-dependent protein kinase 5 holoenzyme complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
+
+[Term]
 id: GO:0016558 ! protein import into peroxisome matrix
 is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
@@ -17061,10 +17047,6 @@
 is_a: GO:0005501 {is_inferred="true"} ! retinoid binding
 
 [Term]
-id: GO:0016935 ! glycine-gated chloride channel complex
-is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
-
-[Term]
 id: GO:0017015 ! regulation of transforming growth factor beta receptor signaling pathway
 is_a: GO:0090092 {is_inferred="true"} ! regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
 is_a: GO:1903844 {is_inferred="true"} ! regulation of cellular response to transforming growth factor beta stimulus
@@ -17078,6 +17060,10 @@
 is_a: GO:0042277 {is_inferred="true"} ! peptide binding
 
 [Term]
+id: GO:0017053 ! transcriptional repressor complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
+
+[Term]
 id: GO:0017055 ! negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
 is_a: GO:0045898 {is_inferred="true"} ! regulation of RNA polymerase II transcriptional preinitiation complex assembly
 is_a: GO:0060633 {is_inferred="true"} ! negative regulation of transcription initiation from RNA polymerase II promoter
@@ -19506,6 +19492,7 @@
 
 [Term]
 id: GO:0019815 ! B cell receptor complex
+is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 is_a: GO:0098802 {is_inferred="true"} ! plasma membrane receptor complex
 
 [Term]
@@ -19604,8 +19591,8 @@
 
 [Term]
 id: GO:0019910 ! mitochondrial pyruvate dehydrogenase (lipoamide) phosphatase complex
+is_a: GO:0044429 {is_inferred="true"} ! mitochondrial part
 is_a: GO:0045253 {is_inferred="true"} ! pyruvate dehydrogenase (lipoamide) phosphatase complex
-is_a: GO:0098798 {is_inferred="true"} ! mitochondrial protein complex
 
 [Term]
 id: GO:0019932 ! second-messenger-mediated signaling
@@ -21506,7 +21493,6 @@
 
 [Term]
 id: GO:0030964 ! NADH dehydrogenase complex
-is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 is_a: GO:1990204 {is_inferred="true"} ! oxidoreductase complex
 
 [Term]
@@ -21879,8 +21865,8 @@
 [Term]
 id: GO:0031211 ! endoplasmic reticulum palmitoyltransferase complex
 is_a: GO:0002178 {is_inferred="true"} ! palmitoyltransferase complex
+is_a: GO:0044425 {is_inferred="true"} ! membrane part
 is_a: GO:0044432 {is_inferred="true"} ! endoplasmic reticulum part
-is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 
 [Term]
 id: GO:0031221 ! arabinan metabolic process
@@ -22390,6 +22376,10 @@
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
 [Term]
+id: GO:0031429 ! box H/ACA snoRNP complex
+is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
+
+[Term]
 id: GO:0031437 ! regulation of mRNA cleavage
 is_a: GO:1903311 {is_inferred="true"} ! regulation of mRNA metabolic process
 
@@ -22489,10 +22479,6 @@
 is_a: GO:0072337 {is_inferred="true"} ! modified amino acid transport
 
 [Term]
-id: GO:0031491 ! nucleosome binding
-is_a: GO:0032403 {is_inferred="true"} ! protein complex binding
-
-[Term]
 id: GO:0031494 ! regulation of mating type switching
 is_a: GO:0010453 {is_inferred="true"} ! regulation of cell fate commitment
 is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
@@ -22522,10 +22508,6 @@
 is_a: GO:1990234 {is_inferred="true"} ! transferase complex
 
 [Term]
-id: GO:0031502 ! dolichyl-phosphate-mannose-protein mannosyltransferase complex
-is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
-
-[Term]
 id: GO:0031504 ! peptidoglycan-based cell wall organization
 is_a: GO:0071555 {is_inferred="true"} ! cell wall organization
 
@@ -23441,7 +23423,6 @@
 [Term]
 id: GO:0032118 ! horsetail-astral microtubule organization
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0071822 {is_inferred="true"} ! protein complex subunit organization
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
@@ -24386,10 +24367,6 @@
 is_a: GO:1990234 {is_inferred="true"} ! transferase complex
 
 [Term]
-id: GO:0032478 ! heterotetrameric decaprenyl diphosphate synthase complex
-is_a: GO:0098800 {is_inferred="true"} ! inner mitochondrial membrane protein complex
-
-[Term]
 id: GO:0032479 ! regulation of type I interferon production
 is_a: GO:0001817 {is_inferred="true"} ! regulation of cytokine production
 
@@ -28286,7 +28263,7 @@
 [Term]
 id: GO:0034245 ! mitochondrial DNA-directed RNA polymerase complex
 is_a: GO:0000428 {is_inferred="true"} ! DNA-directed RNA polymerase complex
-is_a: GO:0098798 {is_inferred="true"} ! mitochondrial protein complex
+is_a: GO:0044429 {is_inferred="true"} ! mitochondrial part
 
 [Term]
 id: GO:0034248 ! regulation of cellular amide metabolic process
@@ -28692,6 +28669,10 @@
 is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
 
 [Term]
+id: GO:0034518 ! RNA cap binding complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
+
+[Term]
 id: GO:0034519 ! cytoplasmic RNA cap binding complex
 is_a: GO:0005845 {is_inferred="true"} ! mRNA cap binding complex
 is_a: GO:0044445 {is_inferred="true"} ! cytosolic part
@@ -28874,11 +28855,10 @@
 
 [Term]
 id: GO:0034708 ! methyltransferase complex
-is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
+is_a: GO:1990234 {is_inferred="true"} ! transferase complex
 
 [Term]
 id: GO:0034728 ! nucleosome organization
-is_a: GO:0071822 {is_inferred="true"} ! protein complex subunit organization
 is_a: GO:0071824 {is_inferred="true"} ! protein-DNA complex subunit organization
 
 [Term]
@@ -29150,10 +29130,6 @@
 is_a: GO:0043279 {is_inferred="true"} ! response to alkaloid
 
 [Term]
-id: GO:0035097 ! histone methyltransferase complex
-is_a: GO:1990234 {is_inferred="true"} ! transferase complex
-
-[Term]
 id: GO:0035100 ! ecdysone binding
 is_a: GO:0032934 {is_inferred="true"} ! sterol binding
 is_a: GO:0043178 {is_inferred="true"} ! alcohol binding
@@ -30610,6 +30586,10 @@
 is_a: GO:0036115 {is_inferred="true"} ! fatty-acyl-CoA catabolic process
 
 [Term]
+id: GO:0036125 ! fatty acid beta-oxidation multienzyme complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
+
+[Term]
 id: GO:0036127 ! 3-sulfino-L-alanine binding
 is_a: GO:0043177 {is_inferred="true"} ! organic acid binding
 is_a: GO:0072341 {is_inferred="true"} ! modified amino acid binding
@@ -30856,7 +30836,6 @@
 [Term]
 id: GO:0036396 ! MIS complex
 is_a: GO:0045293 {is_inferred="true"} ! mRNA editing complex
-is_a: GO:1990234 {is_inferred="true"} ! transferase complex
 
 [Term]
 id: GO:0036405 ! anchored component of cell outer membrane
@@ -32818,10 +32797,6 @@
 is_a: GO:0042714 {is_inferred="true"} ! dosage compensation complex assembly
 
 [Term]
-id: GO:0042719 ! mitochondrial intermembrane space protein transporter complex
-is_a: GO:0098798 {is_inferred="true"} ! mitochondrial protein complex
-
-[Term]
 id: GO:0042720 ! mitochondrial inner membrane peptidase complex
 is_a: GO:0098800 {is_inferred="true"} ! inner mitochondrial membrane protein complex
 
@@ -32945,7 +32920,6 @@
 
 [Term]
 id: GO:0042765 ! GPI-anchor transamidase complex
-is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
 
 [Term]
@@ -33609,7 +33583,6 @@
 
 [Term]
 id: GO:0043020 ! NADPH oxidase complex
-is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 is_a: GO:1990204 {is_inferred="true"} ! oxidoreductase complex
 
 [Term]
@@ -33914,6 +33887,10 @@
 is_a: GO:0044422 {is_inferred="true"} ! organelle part
 
 [Term]
+id: GO:0043235 ! receptor complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
+
+[Term]
 id: GO:0043241 ! protein complex disassembly
 is_a: GO:0032984 {is_inferred="true"} ! macromolecular complex disassembly
 
@@ -34018,7 +33995,7 @@
 [Term]
 id: GO:0043294 ! mitochondrial glutamate synthase complex (NADH)
 is_a: GO:0031027 {is_inferred="true"} ! glutamate synthase complex (NADH)
-is_a: GO:0098798 {is_inferred="true"} ! mitochondrial protein complex
+is_a: GO:0044429 {is_inferred="true"} ! mitochondrial part
 
 [Term]
 id: GO:0043295 ! glutathione binding
@@ -34622,10 +34599,6 @@
 is_a: GO:1901216 {is_inferred="true"} ! positive regulation of neuron death
 
 [Term]
-id: GO:0043527 ! tRNA methyltransferase complex
-is_a: GO:1990234 {is_inferred="true"} ! transferase complex
-
-[Term]
 id: GO:0043531 ! ADP binding
 is_a: GO:0032550 {is_inferred="true"} ! purine ribonucleoside binding
 is_a: GO:0032559 {is_inferred="true"} ! adenyl ribonucleotide binding
@@ -34997,10 +34970,6 @@
 is_a: GO:0043708 {is_inferred="true"} ! cell adhesion involved in biofilm formation
 
 [Term]
-id: GO:0043853 ! methanol-CoM methyltransferase complex
-is_a: GO:1990234 {is_inferred="true"} ! transferase complex
-
-[Term]
 id: GO:0043858 ! arginine:ornithine antiporter activity
 is_a: GO:0015181 {is_inferred="true"} ! arginine transmembrane transporter activity
 is_a: GO:0015297 {is_inferred="true"} ! antiporter activity
@@ -35734,7 +35703,6 @@
 [Term]
 id: GO:0044680 ! methylthiol:coenzyme M methyltransferase complex
 is_a: GO:0034708 {is_inferred="true"} ! methyltransferase complex
-is_a: GO:1990234 {is_inferred="true"} ! transferase complex
 
 [Term]
 id: GO:0044681 ! sulfopyruvate decarboxylase complex
@@ -35748,7 +35716,7 @@
 [Term]
 id: GO:0044695 ! Dsc E3 ubiquitin ligase complex
 is_a: GO:0044422 {is_inferred="true"} ! organelle part
-is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
+is_a: GO:0044425 {is_inferred="true"} ! membrane part
 
 [Term]
 id: GO:0044698 ! morphogenesis of symbiont in host cell
@@ -35891,7 +35859,7 @@
 
 [Term]
 id: GO:0044815 ! DNA packaging complex
-is_a: GO:0043234 {is_inferred="true"} ! protein complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
 
 [Term]
 id: GO:0044827 ! modulation by host of viral genome replication
@@ -36452,13 +36420,12 @@
 
 [Term]
 id: GO:0045281 ! succinate dehydrogenase complex
-is_a: GO:0098803 {is_inferred="true"} ! respiratory chain complex
 is_a: GO:1990204 {is_inferred="true"} ! oxidoreductase complex
 
 [Term]
 id: GO:0045282 ! plasma membrane succinate dehydrogenase complex
+is_a: GO:0044459 {is_inferred="true"} ! plasma membrane part
 is_a: GO:0045281 {is_inferred="true"} ! succinate dehydrogenase complex
-is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
 [Term]
 id: GO:0045283 ! fumarate reductase complex
@@ -41671,10 +41638,6 @@
 is_a: GO:0044703 {is_inferred="true"} ! multi-organism reproductive process
 
 [Term]
-id: GO:0046696 ! lipopolysaccharide receptor complex
-is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
-
-[Term]
 id: GO:0046700 ! heterocycle catabolic process
 is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
 
@@ -42928,7 +42891,6 @@
 id: GO:0048493 ! plasma membrane-derived thylakoid ribulose bisphosphate carboxylase complex
 is_a: GO:0044422 {is_inferred="true"} ! organelle part
 is_a: GO:0044436 {is_inferred="true"} ! thylakoid part
-is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
 [Term]
 id: GO:0048494 ! chromatophore ribulose bisphosphate carboxylase complex
@@ -51165,8 +51127,9 @@
 
 [Term]
 id: GO:0061742 ! chaperone-mediated autophagy translocation complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
+is_a: GO:0044425 {is_inferred="true"} ! membrane part
 is_a: GO:0044437 {is_inferred="true"} ! vacuolar part
-is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 
 [Term]
 id: GO:0061762 ! CAMKK-AMPK signaling cascade
@@ -51228,7 +51191,6 @@
 
 [Term]
 id: GO:0070014 ! sucrase-isomaltase complex
-is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 is_a: GO:1902687 {is_inferred="true"} ! glucosidase complex
 
 [Term]
@@ -52027,7 +51989,7 @@
 
 [Term]
 id: GO:0070418 ! DNA-dependent protein kinase complex
-is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
+is_a: GO:1902554 {is_inferred="true"} ! serine/threonine protein kinase complex
 
 [Term]
 id: GO:0070419 ! nonhomologous end joining complex
@@ -53262,6 +53224,14 @@
 is_a: GO:0050974 {is_inferred="true"} ! detection of mechanical stimulus involved in sensory perception
 
 [Term]
+id: GO:0071012 ! catalytic step 1 spliceosome
+is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
+
+[Term]
+id: GO:0071013 ! catalytic step 2 spliceosome
+is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
+
+[Term]
 id: GO:0071026 ! cytoplasmic RNA surveillance
 is_a: GO:0071025 {is_inferred="true"} ! RNA surveillance
 
@@ -54696,10 +54666,6 @@
 is_a: GO:0070486 {is_inferred="true"} ! leukocyte aggregation
 
 [Term]
-id: GO:0071595 ! Nem1-Spo7 phosphatase complex
-is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
-
-[Term]
 id: GO:0071598 ! neuronal ribonucleoprotein granule
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
 
@@ -56447,6 +56413,10 @@
 is_a: GO:0044428 {is_inferred="true"} ! nuclear part
 
 [Term]
+id: GO:0072589 ! box H/ACA scaRNP complex
+is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
+
+[Term]
 id: GO:0072597 ! maintenance of protein location in chloroplast
 is_a: GO:0051220 {is_inferred="true"} ! cytoplasmic sequestering of protein
 
@@ -59815,7 +59785,7 @@
 
 [Term]
 id: GO:0097106 ! postsynaptic density organization
-is_a: GO:0006996 {is_inferred="true"} ! organelle organization
+is_a: GO:0099084 {is_inferred="true"} ! postsynaptic specialization organization
 
 [Term]
 id: GO:0097107 ! postsynaptic density assembly
@@ -59824,8 +59794,7 @@
 
 [Term]
 id: GO:0097120 ! receptor localization to synapse
-is_a: GO:0031503 {is_inferred="true"} ! protein complex localization
-is_a: GO:0035418 {is_inferred="true"} ! protein localization to synapse
+is_a: GO:0051179 {is_inferred="true"} ! localization
 
 [Term]
 id: GO:0097149 ! centralspindlin complex
@@ -60343,7 +60312,6 @@
 [Term]
 id: GO:0097658 ! Asi complex
 is_a: GO:0044453 {is_inferred="true"} ! nuclear membrane part
-is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 
 [Term]
 id: GO:0097708 ! intracellular vesicle
@@ -60665,6 +60633,10 @@
 is_a: GO:0098636 {is_inferred="true"} ! protein complex involved in cell adhesion
 
 [Term]
+id: GO:0098636 ! protein complex involved in cell adhesion
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
+
+[Term]
 id: GO:0098637 ! protein complex involved in cell-matrix adhesion
 is_a: GO:0098636 {is_inferred="true"} ! protein complex involved in cell adhesion
 
@@ -61013,7 +60985,7 @@
 [Term]
 id: GO:0098802 ! plasma membrane receptor complex
 is_a: GO:0043235 {is_inferred="true"} ! receptor complex
-is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
+is_a: GO:0044459 {is_inferred="true"} ! plasma membrane part
 
 [Term]
 id: GO:0098803 ! respiratory chain complex
@@ -61153,6 +61125,10 @@
 is_a: GO:0005774 {is_inferred="true"} ! vacuolar membrane
 
 [Term]
+id: GO:0098855 ! HCN channel complex
+is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
+
+[Term]
 id: GO:0098856 ! intestinal lipid absorption
 is_a: GO:0006869 {is_inferred="true"} ! lipid transport
 is_a: GO:0044707 {is_inferred="true"} ! single-multicellular organism process
@@ -61509,10 +61485,7 @@
 
 [Term]
 id: GO:0098953 ! receptor diffusion trapping
-is_a: GO:0031503 {is_inferred="true"} ! protein complex localization
 is_a: GO:0051668 {is_inferred="true"} ! localization within membrane
-is_a: GO:0072657 {is_inferred="true"} ! protein localization to membrane
-is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
 
 [Term]
 id: GO:0098954 ! presynaptic endosome membrane
@@ -61598,14 +61571,10 @@
 id: GO:0098970 ! postsynaptic neurotransmitter receptor diffusion trapping
 is_a: GO:0097120 {is_inferred="true"} ! receptor localization to synapse
 is_a: GO:0099628 {is_inferred="true"} ! neurotransmitter receptor diffusion trapping
-is_a: GO:0099645 {is_inferred="true"} ! neurotransmitter receptor localization to postsynaptic specialization membrane
 
 [Term]
 id: GO:0098971 ! anterograde dendritic transport of neurotransmitter receptor complex
-is_a: GO:0035418 {is_inferred="true"} ! protein localization to synapse
 is_a: GO:0098937 {is_inferred="true"} ! anterograde dendritic transport
-is_a: GO:0099637 {is_inferred="true"} ! neurotransmitter receptor transport
-is_a: GO:0099640 {is_inferred="true"} ! axo-dendritic protein transport
 
 [Term]
 id: GO:0098972 ! anterograde dendritic transport of mitochondrion
@@ -61731,7 +61700,7 @@
 
 [Term]
 id: GO:0099023 ! tethring complex
-is_a: GO:0043234 {is_inferred="true"} ! protein complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
 
 [Term]
 id: GO:0099025 ! anchored component of postsynaptic membrane
@@ -61939,6 +61908,15 @@
 is_a: GO:0099540 {is_inferred="true"} ! trans-synaptic signaling by neuropeptide
 
 [Term]
+id: GO:0099083 ! retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission
+is_a: GO:0099082 {is_inferred="true"} ! retrograde trans-synaptic signaling by neuropeptide
+is_a: GO:0099551 {is_inferred="true"} ! trans-synaptic signaling by neuropeptide, modulating synaptic transmission
+
+[Term]
+id: GO:0099084 ! postsynaptic specialization organization
+is_a: GO:0006996 {is_inferred="true"} ! organelle organization
+
+[Term]
 id: GO:0099400 ! caveola neck
 is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
 
@@ -62069,6 +62047,7 @@
 
 [Term]
 id: GO:0099551 ! trans-synaptic signaling by neuropeptide, modulating synaptic transmission
+is_a: GO:0099540 {is_inferred="true"} ! trans-synaptic signaling by neuropeptide
 is_a: GO:0099550 {is_inferred="true"} ! trans-synaptic signalling, modulating synaptic transmission
 
 [Term]
@@ -62171,11 +62150,6 @@
 is_a: GO:0098657 {is_inferred="true"} ! import into cell
 
 [Term]
-id: GO:0099590 ! neurotransmitter receptor internalization
-is_a: GO:0019538 {is_inferred="true"} ! protein metabolic process
-is_a: GO:0099637 {is_inferred="true"} ! neurotransmitter receptor transport
-
-[Term]
 id: GO:0099601 ! regulation of neurotransmitter receptor activity
 is_a: GO:0010469 {is_inferred="true"} ! regulation of receptor activity
 
@@ -62256,10 +62230,6 @@
 is_a: GO:0099626 {is_inferred="true"} ! voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium ion concentration
 
 [Term]
-id: GO:0099637 ! neurotransmitter receptor transport
-is_a: GO:0031503 {is_inferred="true"} ! protein complex localization
-
-[Term]
 id: GO:0099638 ! endosome to plasma membrane protein transport
 is_a: GO:0015031 {is_inferred="true"} ! protein transport
 is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
@@ -62295,7 +62265,6 @@
 
 [Term]
 id: GO:0099645 ! neurotransmitter receptor localization to postsynaptic specialization membrane
-is_a: GO:0031503 {is_inferred="true"} ! protein complex localization
 is_a: GO:0099633 {is_inferred="true"} ! protein localization to postsynaptic specialization membrane
 
 [Term]
@@ -75358,11 +75327,11 @@
 
 [Term]
 id: GO:1902494 ! catalytic complex
-is_a: GO:0043234 {is_inferred="true"} ! protein complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
 
 [Term]
 id: GO:1902495 ! transmembrane transporter complex
-is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
+is_a: GO:0044425 {is_inferred="true"} ! membrane part
 
 [Term]
 id: GO:1902496 ! protein binding involved in negative regulation of telomere maintenance via telomerase
@@ -75645,7 +75614,7 @@
 
 [Term]
 id: GO:1902555 ! endoribonuclease complex
-is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
+is_a: GO:1905348 {is_inferred="true"} ! endonuclease complex
 
 [Term]
 id: GO:1902557 ! 5'-adenylyl sulfate transmembrane transporter activity
@@ -76271,7 +76240,7 @@
 
 [Term]
 id: GO:1902683 ! regulation of receptor localization to synapse
-is_a: GO:1902473 {is_inferred="true"} ! regulation of protein localization to synapse
+is_a: GO:0032879 {is_inferred="true"} ! regulation of localization
 
 [Term]
 id: GO:1902684 ! negative regulation of receptor localization to synapse
@@ -76280,7 +76249,7 @@
 
 [Term]
 id: GO:1902685 ! positive regulation of receptor localization to synapse
-is_a: GO:1902474 {is_inferred="true"} ! positive regulation of protein localization to synapse
+is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
 is_a: GO:1902683 {is_inferred="true"} ! regulation of receptor localization to synapse
 
 [Term]
@@ -76325,7 +76294,7 @@
 
 [Term]
 id: GO:1902695 ! metallochaperone complex
-is_a: GO:0043234 {is_inferred="true"} ! protein complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
 
 [Term]
 id: GO:1902696 ! glycine catabolic process to isobutanol
@@ -76674,7 +76643,7 @@
 
 [Term]
 id: GO:1902773 ! GTPase activator complex
-is_a: GO:0043234 {is_inferred="true"} ! protein complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
 
 [Term]
 id: GO:1902774 ! late endosome to lysosome transport
@@ -78254,7 +78223,6 @@
 [Term]
 id: GO:1903095 ! ribonuclease III complex
 is_a: GO:1902555 {is_inferred="true"} ! endoribonuclease complex
-is_a: GO:1905348 {is_inferred="true"} ! endonuclease complex
 
 [Term]
 id: GO:1903096 ! protein localization to meiotic spindle midzone
@@ -78263,13 +78231,11 @@
 [Term]
 id: GO:1903097 ! regulation of CENP-A containing nucleosome assembly
 is_a: GO:0010847 {is_inferred="true"} ! regulation of chromatin assembly
-is_a: GO:0043254 {is_inferred="true"} ! regulation of protein complex assembly
 is_a: GO:0090230 {is_inferred="true"} ! regulation of centromere complex assembly
 is_a: GO:1900049 {is_inferred="true"} ! regulation of histone exchange
 
 [Term]
 id: GO:1903098 ! negative regulation of CENP-A containing nucleosome assembly
-is_a: GO:0031333 {is_inferred="true"} ! negative regulation of protein complex assembly
 is_a: GO:0045798 {is_inferred="true"} ! negative regulation of chromatin assembly or disassembly
 is_a: GO:1900050 {is_inferred="true"} ! negative regulation of histone exchange
 is_a: GO:1903097 {is_inferred="true"} ! regulation of CENP-A containing nucleosome assembly
@@ -78277,7 +78243,7 @@
 
 [Term]
 id: GO:1903099 ! positive regulation of CENP-A containing nucleosome assembly
-is_a: GO:0031334 {is_inferred="true"} ! positive regulation of protein complex assembly
+is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
 is_a: GO:0045799 {is_inferred="true"} ! positive regulation of chromatin assembly or disassembly
 is_a: GO:1900051 {is_inferred="true"} ! positive regulation of histone exchange
 is_a: GO:1903097 {is_inferred="true"} ! regulation of CENP-A containing nucleosome assembly
@@ -78812,7 +78778,6 @@
 id: GO:1903221 ! regulation of mitotic recombination involved in replication fork processing
 is_a: GO:0000019 {is_inferred="true"} ! regulation of mitotic recombination
 is_a: GO:0090329 {is_inferred="true"} ! regulation of DNA-dependent DNA replication
-is_a: GO:2001020 {is_inferred="true"} ! regulation of response to DNA damage stimulus
 
 [Term]
 id: GO:1903222 ! quinolinic acid transmembrane transport
@@ -79043,7 +79008,7 @@
 
 [Term]
 id: GO:1903269 ! ornithine carbamoyltransferase inhibitor complex
-is_a: GO:0043234 {is_inferred="true"} ! protein complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
 
 [Term]
 id: GO:1903270 ! regulation of cytoplasmic translational elongation through polyproline stretches
@@ -80193,11 +80158,11 @@
 
 [Term]
 id: GO:1903502 ! translation repressor complex
-is_a: GO:0043234 {is_inferred="true"} ! protein complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
 
 [Term]
 id: GO:1903503 ! ATPase inhibitor complex
-is_a: GO:0043234 {is_inferred="true"} ! protein complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
 
 [Term]
 id: GO:1903504 ! regulation of mitotic spindle checkpoint
@@ -81963,7 +81928,7 @@
 
 [Term]
 id: GO:1903865 ! sigma factor antagonist complex
-is_a: GO:0043234 {is_inferred="true"} ! protein complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
 
 [Term]
 id: GO:1903866 ! palisade mesophyll development
@@ -83049,7 +83014,7 @@
 
 [Term]
 id: GO:1904090 ! peptidase inhibitor complex
-is_a: GO:0043234 {is_inferred="true"} ! protein complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
 
 [Term]
 id: GO:1904091 ! peptidyl carrier protein activity involved in nonribosomal peptide biosynthesis
@@ -86379,11 +86344,11 @@
 
 [Term]
 id: GO:1904763 ! chaperone-mediated autophagy translocation complex assembly
-is_a: GO:0006461 {is_inferred="true"} ! protein complex assembly
+is_a: GO:0065003 {is_inferred="true"} ! macromolecular complex assembly
 
 [Term]
 id: GO:1904764 ! chaperone-mediated autophagy translocation complex disassembly
-is_a: GO:0043241 {is_inferred="true"} ! protein complex disassembly
+is_a: GO:0032984 {is_inferred="true"} ! macromolecular complex disassembly
 
 [Term]
 id: GO:1904765 ! positive regulation of transcription from RNA polymerase II promoter in response to maltose
@@ -86661,7 +86626,7 @@
 
 [Term]
 id: GO:1904824 ! anaphase-promoting complex assembly
-is_a: GO:0006461 {is_inferred="true"} ! protein complex assembly
+is_a: GO:0065003 {is_inferred="true"} ! macromolecular complex assembly
 
 [Term]
 id: GO:1904825 ! protein localization to microtubule plus-end
@@ -89264,7 +89229,7 @@
 
 [Term]
 id: GO:1905354 ! exoribonuclease complex
-is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
+is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
 
 [Term]
 id: GO:1905355 ! spine apparatus assembly
@@ -90168,7 +90133,6 @@
 
 [Term]
 id: GO:1990077 ! primosome complex
-is_a: GO:0043234 {is_inferred="true"} ! protein complex
 is_a: GO:0044427 {is_inferred="true"} ! chromosomal part
 
 [Term]
@@ -90185,7 +90149,7 @@
 
 [Term]
 id: GO:1990104 ! DNA bending complex
-is_a: GO:0043234 {is_inferred="true"} ! protein complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
 
 [Term]
 id: GO:1990109 ! rejection of pollen from other species
@@ -90283,7 +90247,7 @@
 
 [Term]
 id: GO:1990203 ! MdtBC Complex
-is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
+is_a: GO:0044459 {is_inferred="true"} ! plasma membrane part
 
 [Term]
 id: GO:1990204 ! oxidoreductase complex
@@ -90297,7 +90261,7 @@
 
 [Term]
 id: GO:1990207 ! EmrE multidrug transporter complex
-is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
+is_a: GO:0044459 {is_inferred="true"} ! plasma membrane part
 
 [Term]
 id: GO:1990215 ! negative regulation by symbiont of host intracellular transport
@@ -90314,6 +90278,7 @@
 
 [Term]
 id: GO:1990229 ! iron-sulfur cluster assembly complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
 is_a: GO:0044445 {is_inferred="true"} ! cytosolic part
 
 [Term]
@@ -90351,9 +90316,13 @@
 
 [Term]
 id: GO:1990246 ! uniplex complex
-is_a: GO:0098800 {is_inferred="true"} ! inner mitochondrial membrane protein complex
+is_a: GO:0044455 {is_inferred="true"} ! mitochondrial membrane part
 
 [Term]
+id: GO:1990249 ! nucleotide-excision repair, DNA damage recognition complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
+
+[Term]
 id: GO:1990252 ! Syp1 complex
 is_a: GO:0044433 {is_inferred="true"} ! cytoplasmic vesicle part
 
@@ -90424,10 +90393,9 @@
 
 [Term]
 id: GO:1990332 ! Ire1 complex
+is_a: GO:0044425 {is_inferred="true"} ! membrane part
 is_a: GO:0044432 {is_inferred="true"} ! endoplasmic reticulum part
-is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 is_a: GO:1902555 {is_inferred="true"} ! endoribonuclease complex
-is_a: GO:1905348 {is_inferred="true"} ! endonuclease complex
 
 [Term]
 id: GO:1990333 ! mitotic checkpoint complex, CDC20-MAD2 subcomplex
@@ -90447,6 +90415,10 @@
 is_a: GO:1902410 {is_inferred="true"} ! mitotic cytokinetic process
 
 [Term]
+id: GO:1990351 ! transporter complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
+
+[Term]
 id: GO:1990361 ! PKM2 pyruvate kinase complex
 is_a: GO:1902912 {is_inferred="true"} ! pyruvate kinase complex
 
@@ -90458,8 +90430,13 @@
 [Term]
 id: GO:1990389 ! CUE1-UBC7 ubiquitin-conjugating enzyme complex
 is_a: GO:0031371 {is_inferred="true"} ! ubiquitin conjugating enzyme complex
+is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 
 [Term]
+id: GO:1990391 ! DNA repair complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
+
+[Term]
 id: GO:1990392 ! EFF-1 complex
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
@@ -90469,7 +90446,7 @@
 
 [Term]
 id: GO:1990398 ! Cus cation efflux complex
-is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
+is_a: GO:0044459 {is_inferred="true"} ! plasma membrane part
 
 [Term]
 id: GO:1990406 ! CGRP receptor complex
@@ -90476,6 +90453,10 @@
 is_a: GO:1903439 {is_inferred="true"} ! calcitonin family receptor complex
 
 [Term]
+id: GO:1990415 ! Pex17p-Pex14p docking complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
+
+[Term]
 id: GO:1990417 ! snoRNA release from pre-rRNA
 is_a: GO:0016074 {is_inferred="true"} ! snoRNA metabolic process
 
@@ -90884,6 +90865,10 @@
 is_a: GO:0051650 {is_inferred="true"} ! establishment of vesicle localization
 
 [Term]
+id: GO:1990779 ! glycoprotein Ib-IX-V complex
+is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
+
+[Term]
 id: GO:1990780 ! cytoplasmic side of dendritic spine plasma membrane
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
 is_a: GO:0044463 {is_inferred="true"} ! cell projection part
@@ -90970,8 +90955,8 @@
 
 [Term]
 id: GO:1990862 ! nuclear membrane complex Bqt3-Bqt4
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
 is_a: GO:0044453 {is_inferred="true"} ! nuclear membrane part
-is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 
 [Term]
 id: GO:1990872 ! negative regulation of sterol import by negative regulation of transcription from RNA polymerase II promoter
@@ -91022,6 +91007,10 @@
 is_a: GO:1990139 {is_inferred="true"} ! protein localization to nuclear periphery
 
 [Term]
+id: GO:1990923 ! PET complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
+
+[Term]
 id: GO:1990925 ! mitochondrial iron ion transmembrane transport
 is_a: GO:0034755 {is_inferred="true"} ! iron ion transmembrane transport
 is_a: GO:0048250 {is_inferred="true"} ! mitochondrial iron ion transport
------------------------------------------------------------------------
r35965 | paola | 2016-10-03 05:42:25 -0700 (Mon, 03 Oct 2016) | 3 lines

GH Exosome assembly and secretion #12386 - closed - added GO:0097734 ’extracellular exosome biogenesis’

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35970)
+++ go_inferences.obo	(working copy)
@@ -80379,6 +80379,7 @@
 [Term]
 id: GO:1903541 ! regulation of exosomal secretion
 is_a: GO:0017157 {is_inferred="true"} ! regulation of exocytosis
+is_a: GO:0044087 {is_inferred="true"} ! regulation of cellular component biogenesis
 
 [Term]
 id: GO:1903542 ! negative regulation of exosomal secretion
@@ -80387,6 +80388,7 @@
 
 [Term]
 id: GO:1903543 ! positive regulation of exosomal secretion
+is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
 is_a: GO:0045921 {is_inferred="true"} ! positive regulation of exocytosis
 is_a: GO:1903541 {is_inferred="true"} ! regulation of exosomal secretion
 
------------------------------------------------------------------------
r35961 | termgenie | 2016-10-03 01:51:09 -0700 (Mon, 03 Oct 2016) | 4 lines

TermGenie commit for user: rl reviewed by dos

changes in entailments

------------------------------------------------------------------------
r35961 | termgenie | 2016-10-03 01:51:09 -0700 (Mon, 03 Oct 2016) | 4 lines

TermGenie commit for user: rl reviewed by dos

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35961)
+++ go_inferences.obo	(working copy)
@@ -42511,7 +42511,7 @@
 
 [Term]
 id: GO:0048246 ! macrophage chemotaxis
-is_a: GO:0097529 {is_inferred="true"} ! myeloid leukocyte migration
+is_a: GO:1905517 {is_inferred="true"} ! macrophage migration
 
 [Term]
 id: GO:0048250 ! mitochondrial iron ion transport
@@ -54585,7 +54585,7 @@
 
 [Term]
 id: GO:0071539 ! protein localization to centrosome
-is_a: GO:0072698 {is_inferred="true"} ! protein localization to microtubule cytoskeleton
+is_a: GO:1905508 {is_inferred="true"} ! protein localization to microtubule organizing center
 
 [Term]
 id: GO:0071543 ! diphosphoinositol polyphosphate metabolic process
@@ -55350,7 +55350,7 @@
 
 [Term]
 id: GO:0071988 ! protein localization to spindle pole body
-is_a: GO:0072698 {is_inferred="true"} ! protein localization to microtubule cytoskeleton
+is_a: GO:1905508 {is_inferred="true"} ! protein localization to microtubule organizing center
 
 [Term]
 id: GO:0071989 ! establishment of protein localization to spindle pole body
@@ -75135,11 +75135,13 @@
 [Term]
 id: GO:1902440 ! protein localization to mitotic spindle pole body
 is_a: GO:1902480 {is_inferred="true"} ! protein localization to mitotic spindle
+is_a: GO:1905508 {is_inferred="true"} ! protein localization to microtubule organizing center
 
 [Term]
 id: GO:1902441 ! protein localization to meiotic spindle pole body
 is_a: GO:0022414 {is_inferred="true"} ! reproductive process
 is_a: GO:1905359 {is_inferred="true"} ! protein localization to meiotic spindle
+is_a: GO:1905508 {is_inferred="true"} ! protein localization to microtubule organizing center
 
 [Term]
 id: GO:1902442 ! regulation of ripoptosome assembly involved in necroptotic process
@@ -83218,7 +83220,7 @@
 [Term]
 id: GO:1904124 ! microglial cell migration
 is_a: GO:0008347 {is_inferred="true"} ! glial cell migration
-is_a: GO:0097529 {is_inferred="true"} ! myeloid leukocyte migration
+is_a: GO:1905517 {is_inferred="true"} ! macrophage migration
 
 [Term]
 id: GO:1904125 ! convergent extension involved in rhombomere morphogenesis
@@ -86356,8 +86358,8 @@
 
 [Term]
 id: GO:1904759 ! protein localization to equatorial microtubule organizing center
-is_a: GO:0072698 {is_inferred="true"} ! protein localization to microtubule cytoskeleton
 is_a: GO:0072741 {is_inferred="true"} ! protein localization to cell division site
+is_a: GO:1905508 {is_inferred="true"} ! protein localization to microtubule organizing center
 
 [Term]
 id: GO:1904760 ! regulation of myofibroblast differentiation
@@ -89993,6 +89995,14 @@
 is_a: GO:1905482 {is_inferred="true"} ! cytoplasmic sequestering of protein involved in G2 DNA damage checkpoint
 
 [Term]
+id: GO:1905508 ! protein localization to microtubule organizing center
+is_a: GO:0072698 {is_inferred="true"} ! protein localization to microtubule cytoskeleton
+
+[Term]
+id: GO:1905509 ! protein localization to interphase microtubule organizing center
+is_a: GO:1905508 {is_inferred="true"} ! protein localization to microtubule organizing center
+
+[Term]
 id: GO:1905510 ! negative regulation of myosin II filament assembly
 is_a: GO:0031333 {is_inferred="true"} ! negative regulation of protein complex assembly
 is_a: GO:0043520 {is_inferred="true"} ! regulation of myosin II filament assembly
@@ -90005,6 +90015,20 @@
 is_a: GO:1904901 {is_inferred="true"} ! positive regulation of myosin II filament organization
 
 [Term]
+id: GO:1905512 ! regulation of short-term synaptic potentiation
+is_a: GO:0048167 {is_inferred="true"} ! regulation of synaptic plasticity
+
+[Term]
+id: GO:1905513 ! negative regulation of short-term synaptic potentiation
+is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
+is_a: GO:1905512 {is_inferred="true"} ! regulation of short-term synaptic potentiation
+
+[Term]
+id: GO:1905514 ! positive regulation of short-term synaptic potentiation
+is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
+is_a: GO:1905512 {is_inferred="true"} ! regulation of short-term synaptic potentiation
+
+[Term]
 id: GO:1905515 ! non-motile cilium assembly
 is_a: GO:0042384 {is_inferred="true"} ! cilium assembly
 
@@ -90015,6 +90039,26 @@
 is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
 
 [Term]
+id: GO:1905517 ! macrophage migration
+is_a: GO:0097529 {is_inferred="true"} ! myeloid leukocyte migration
+
+[Term]
+id: GO:1905518 ! regulation of presynaptic active zone assembly
+is_a: GO:0044087 {is_inferred="true"} ! regulation of cellular component biogenesis
+is_a: GO:0050807 {is_inferred="true"} ! regulation of synapse organization
+
+[Term]
+id: GO:1905519 ! negative regulation of presynaptic active zone assembly
+is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
+is_a: GO:1905518 {is_inferred="true"} ! regulation of presynaptic active zone assembly
+
+[Term]
+id: GO:1905520 ! positive regulation of presynaptic active zone assembly
+is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
+is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
+is_a: GO:1905518 {is_inferred="true"} ! regulation of presynaptic active zone assembly
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35950 | dph | 2016-10-02 11:22:01 -0700 (Sun, 02 Oct 2016) | 2 lines

Removed bad axioms from nanoparticle terms, GO:1990268 and GO:1990267.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35950)
+++ go_inferences.obo	(working copy)
@@ -11281,7 +11281,6 @@
 [Term]
 id: GO:0010039 ! response to iron ion
 is_a: GO:0010038 {is_inferred="true"} ! response to metal ion
-is_a: GO:1990267 {is_inferred="true"} ! response to transition metal nanoparticle
 
 [Term]
 id: GO:0010040 ! response to iron(II) ion
@@ -11294,12 +11293,10 @@
 [Term]
 id: GO:0010042 ! response to manganese ion
 is_a: GO:0010038 {is_inferred="true"} ! response to metal ion
-is_a: GO:1990267 {is_inferred="true"} ! response to transition metal nanoparticle
 
 [Term]
 id: GO:0010043 ! response to zinc ion
 is_a: GO:0010038 {is_inferred="true"} ! response to metal ion
-is_a: GO:1990267 {is_inferred="true"} ! response to transition metal nanoparticle
 
 [Term]
 id: GO:0010044 ! response to aluminum ion
@@ -11749,7 +11746,6 @@
 [Term]
 id: GO:0010272 ! response to silver ion
 is_a: GO:0010038 {is_inferred="true"} ! response to metal ion
-is_a: GO:1990267 {is_inferred="true"} ! response to transition metal nanoparticle
 
 [Term]
 id: GO:0010273 ! detoxification of copper ion
@@ -27401,7 +27397,6 @@
 id: GO:0033590 ! response to cobalamin
 is_a: GO:0010243 {is_inferred="true"} ! response to organonitrogen compound
 is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
-is_a: GO:1990267 {is_inferred="true"} ! response to transition metal nanoparticle
 
 [Term]
 id: GO:0033591 ! response to L-ascorbic acid
@@ -41658,17 +41653,14 @@
 id: GO:0046687 ! response to chromate
 is_a: GO:0010035 {is_inferred="true"} ! response to inorganic substance
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
-is_a: GO:1990267 {is_inferred="true"} ! response to transition metal nanoparticle
 
 [Term]
 id: GO:0046688 ! response to copper ion
 is_a: GO:0010038 {is_inferred="true"} ! response to metal ion
-is_a: GO:1990267 {is_inferred="true"} ! response to transition metal nanoparticle
 
 [Term]
 id: GO:0046689 ! response to mercury ion
 is_a: GO:0010038 {is_inferred="true"} ! response to metal ion
-is_a: GO:1990267 {is_inferred="true"} ! response to transition metal nanoparticle
 
 [Term]
 id: GO:0046690 ! response to tellurium ion
@@ -46280,7 +46272,6 @@
 [Term]
 id: GO:0051597 ! response to methylmercury
 is_a: GO:0010033 {is_inferred="true"} ! response to organic substance
-is_a: GO:1990267 {is_inferred="true"} ! response to transition metal nanoparticle
 
 [Term]
 id: GO:0051600 ! regulation of endocytosis by exocyst localization
@@ -56605,7 +56596,7 @@
 
 [Term]
 id: GO:0072718 ! response to cisplatin
-is_a: GO:1990267 {is_inferred="true"} ! response to transition metal nanoparticle
+is_a: GO:0042221 {is_inferred="true"} ! response to chemical
 
 [Term]
 id: GO:0072719 ! cellular response to cisplatin
@@ -60097,7 +60088,7 @@
 
 [Term]
 id: GO:0097328 ! response to carboplatin
-is_a: GO:1990267 {is_inferred="true"} ! response to transition metal nanoparticle
+is_a: GO:0042221 {is_inferred="true"} ! response to chemical
 
 [Term]
 id: GO:0097330 ! response to 5-fluoro-2'-deoxyuridine
@@ -75135,7 +75126,6 @@
 id: GO:1902438 ! response to vanadate(3-)
 is_a: GO:0010035 {is_inferred="true"} ! response to inorganic substance
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
-is_a: GO:1990267 {is_inferred="true"} ! response to transition metal nanoparticle
 
 [Term]
 id: GO:1902439 ! cellular response to vanadate(3-)
@@ -84156,7 +84146,6 @@
 [Term]
 id: GO:1904311 ! response to gold(3+)
 is_a: GO:0010035 {is_inferred="true"} ! response to inorganic substance
-is_a: GO:1990268 {is_inferred="true"} ! response to gold nanoparticle
 
 [Term]
 id: GO:1904312 ! cellular response to gold(3+)
------------------------------------------------------------------------
r35948 | dph | 2016-10-02 10:48:44 -0700 (Sun, 02 Oct 2016) | 2 lines

Made the definition of mitotic nuclear divsion more specific to the mitotic cell cycle. GH12698-closed

changes in entailments

------------------------------------------------------------------------
r35927 | hjd | 2016-09-30 13:18:46 -0700 (Fri, 30 Sep 2016) | 2 lines

added about 70 plant enzyme activities

changes in entailments

------------------------------------------------------------------------
r35925 | cjm | 2016-09-30 10:10:33 -0700 (Fri, 30 Sep 2016) | 1 line

link between blepharoplast and plant cell

changes in entailments

------------------------------------------------------------------------
r35923 | cjm | 2016-09-30 09:59:19 -0700 (Fri, 30 Sep 2016) | 1 line

removing trailing dash for EC xrefs

changes in entailments

------------------------------------------------------------------------
r35921 | paola | 2016-09-30 08:59:38 -0700 (Fri, 30 Sep 2016) | 2 lines

GH NTRs/OTRs: types of cilia #12462 - work in progress - cleaning up

changes in entailments

------------------------------------------------------------------------
r35919 | paola | 2016-09-30 08:32:10 -0700 (Fri, 30 Sep 2016) | 2 lines

GH NTRs/OTRs: types of cilia #12462 - work in progress - merged 'primary cilium' into 'cilium'

changes in entailments

------------------------------------------------------------------------
r35917 | paola | 2016-09-30 08:04:32 -0700 (Fri, 30 Sep 2016) | 3 lines

GH NTRs/OTRs: types of cilia #12462 - work in progress - fixed synonym scopes for ‘regulation of motile primary cilium assembly’ terms

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35917)
+++ go_inferences.obo	(working copy)
@@ -89981,18 +89981,18 @@
 is_a: GO:1901681 {is_inferred="true"} ! sulfur compound binding
 
 [Term]
-id: GO:1905503 ! regulation of motile primary cilium assembly
+id: GO:1905503 ! regulation of motile cilium assembly
 is_a: GO:1902017 {is_inferred="true"} ! regulation of cilium assembly
 
 [Term]
-id: GO:1905504 ! negative regulation of motile primary cilium assembly
+id: GO:1905504 ! negative regulation of motile cilium assembly
 is_a: GO:1902018 {is_inferred="true"} ! negative regulation of cilium assembly
-is_a: GO:1905503 {is_inferred="true"} ! regulation of motile primary cilium assembly
+is_a: GO:1905503 {is_inferred="true"} ! regulation of motile cilium assembly
 
 [Term]
-id: GO:1905505 ! positive regulation of motile primary cilium assembly
+id: GO:1905505 ! positive regulation of motile cilium assembly
 is_a: GO:0045724 {is_inferred="true"} ! positive regulation of cilium assembly
-is_a: GO:1905503 {is_inferred="true"} ! regulation of motile primary cilium assembly
+is_a: GO:1905503 {is_inferred="true"} ! regulation of motile cilium assembly
 
 [Term]
 id: GO:1905506 ! gerontoplast stroma
------------------------------------------------------------------------
r35914 | paola | 2016-09-30 07:47:08 -0700 (Fri, 30 Sep 2016) | 2 lines

GH OTR: add logical definition for 'regulation of fertilization' #12695 - closed - added logical def to 'regulation of fertilization'

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35914)
+++ go_inferences.obo	(working copy)
@@ -33584,10 +33584,9 @@
 
 [Term]
 id: GO:0043012 ! regulation of fusion of sperm to egg plasma membrane
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
-is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
+is_a: GO:0080154 {is_inferred="true"} ! regulation of fertilization
 
 [Term]
 id: GO:0043013 ! negative regulation of fusion of sperm to egg plasma membrane
@@ -47725,8 +47724,7 @@
 
 [Term]
 id: GO:0060046 ! regulation of acrosome reaction
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
-is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
+is_a: GO:0080154 {is_inferred="true"} ! regulation of fertilization
 
 [Term]
 id: GO:0060049 ! regulation of protein glycosylation
@@ -48673,6 +48671,7 @@
 [Term]
 id: GO:0060467 ! negative regulation of fertilization
 is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
+is_a: GO:0080154 {is_inferred="true"} ! regulation of fertilization
 is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
 
 [Term]
@@ -90023,6 +90022,7 @@
 [Term]
 id: GO:1905516 ! positive regulation of fertilization
 is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
+is_a: GO:0080154 {is_inferred="true"} ! regulation of fertilization
 is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
 
 [Term]
@@ -92888,9 +92888,8 @@
 
 [Term]
 id: GO:2000359 ! regulation of binding of sperm to zona pellucida
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
-is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
+is_a: GO:0080154 {is_inferred="true"} ! regulation of fertilization
 
 [Term]
 id: GO:2000360 ! negative regulation of binding of sperm to zona pellucida
------------------------------------------------------------------------
r35912 | termgenie | 2016-09-30 07:35:40 -0700 (Fri, 30 Sep 2016) | 2 lines

TermGenie commit for user: pr reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35912)
+++ go_inferences.obo	(working copy)
@@ -48696,8 +48696,8 @@
 
 [Term]
 id: GO:0060472 ! positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:0050867 {is_inferred="true"} ! positive regulation of cell activation
+is_a: GO:1905516 {is_inferred="true"} ! positive regulation of fertilization
 
 [Term]
 id: GO:0060474 ! positive regulation of flagellated sperm motility involved in capacitation
@@ -90021,6 +90021,11 @@
 is_a: GO:0042384 {is_inferred="true"} ! cilium assembly
 
 [Term]
+id: GO:1905516 ! positive regulation of fertilization
+is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
+is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
@@ -92802,8 +92807,8 @@
 
 [Term]
 id: GO:2000344 ! positive regulation of acrosome reaction
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:0060046 {is_inferred="true"} ! regulation of acrosome reaction
+is_a: GO:1905516 {is_inferred="true"} ! positive regulation of fertilization
 
 [Term]
 id: GO:2000345 ! regulation of hepatocyte proliferation
------------------------------------------------------------------------
r35910 | paola | 2016-09-30 07:09:05 -0700 (Fri, 30 Sep 2016) | 2 lines

Fixing build

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35910)
+++ go_inferences.obo	(working copy)
@@ -60260,7 +60260,7 @@
 is_a: GO:0044445 {is_inferred="true"} ! cytosolic part
 
 [Term]
-id: GO:0097500 ! receptor localization to nonmotile primary cilium
+id: GO:0097500 ! receptor localization to non-motile cilium
 is_a: GO:1903441 {is_inferred="true"} ! protein localization to ciliary membrane
 
 [Term]
@@ -61030,7 +61030,7 @@
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 
 [Term]
-id: GO:0098804 ! nonmotile primary cilium membrane
+id: GO:0098804 ! non-motile cilium membrane
 is_a: GO:0060170 {is_inferred="true"} ! ciliary membrane
 
 [Term]
@@ -80412,7 +80412,7 @@
 
 [Term]
 id: GO:1903546 ! protein localization to photoreceptor outer segment
-is_a: GO:0061512 {is_inferred="true"} ! protein localization to cilium
+is_a: GO:0097499 {is_inferred="true"} ! protein localization to non-motile cilium
 
 [Term]
 id: GO:1903547 ! regulation of growth hormone activity
@@ -80797,6 +80797,7 @@
 
 [Term]
 id: GO:1903621 ! protein localization to photoreceptor connecting cilium
+is_a: GO:0097499 {is_inferred="true"} ! protein localization to non-motile cilium
 is_a: GO:1904491 {is_inferred="true"} ! protein localization to ciliary transition zone
 
 [Term]
------------------------------------------------------------------------
r35906 | paola | 2016-09-30 06:04:07 -0700 (Fri, 30 Sep 2016) | 2 lines

GH NTRs/OTRs: types of cilia #12462 - work in progress - merged ‘nonmotile primary cilium’ terms into ‘non-motile cilium’ ones

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35906)
+++ go_inferences.obo	(working copy)
@@ -77072,18 +77072,18 @@
 is_a: GO:1902852 {is_inferred="true"} ! regulation of nuclear migration during mitotic telophase
 
 [Term]
-id: GO:1902855 ! regulation of nonmotile primary cilium assembly
+id: GO:1902855 ! regulation of non-motile cilium assembly
 is_a: GO:1902017 {is_inferred="true"} ! regulation of cilium assembly
 
 [Term]
-id: GO:1902856 ! negative regulation of nonmotile primary cilium assembly
+id: GO:1902856 ! negative regulation of non-motile cilium assembly
 is_a: GO:1902018 {is_inferred="true"} ! negative regulation of cilium assembly
-is_a: GO:1902855 {is_inferred="true"} ! regulation of nonmotile primary cilium assembly
+is_a: GO:1902855 {is_inferred="true"} ! regulation of non-motile cilium assembly
 
 [Term]
-id: GO:1902857 ! positive regulation of nonmotile primary cilium assembly
+id: GO:1902857 ! positive regulation of non-motile cilium assembly
 is_a: GO:0045724 {is_inferred="true"} ! positive regulation of cilium assembly
-is_a: GO:1902855 {is_inferred="true"} ! regulation of nonmotile primary cilium assembly
+is_a: GO:1902855 {is_inferred="true"} ! regulation of non-motile cilium assembly
 
 [Term]
 id: GO:1902858 ! propionyl-CoA metabolic process
------------------------------------------------------------------------
r35900 | termgenie | 2016-09-30 04:58:26 -0700 (Fri, 30 Sep 2016) | 2 lines

TermGenie commit for user: pr reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35900)
+++ go_inferences.obo	(working copy)
@@ -90016,6 +90016,10 @@
 is_a: GO:1904901 {is_inferred="true"} ! positive regulation of myosin II filament organization
 
 [Term]
+id: GO:1905515 ! non-motile cilium assembly
+is_a: GO:0042384 {is_inferred="true"} ! cilium assembly
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35898 | paola | 2016-09-30 03:57:21 -0700 (Fri, 30 Sep 2016) | 2 lines

Fixing build

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35898)
+++ go_inferences.obo	(working copy)
@@ -82064,7 +82064,7 @@
 is_a: GO:1903884 {is_inferred="true"} ! regulation of chemokine (C-C motif) ligand 20 production
 
 [Term]
-id: GO:1903887 ! motile primary cilium assembly
+id: GO:1903887 ! motile cilium assembly
 is_a: GO:0042384 {is_inferred="true"} ! cilium assembly
 
 [Term]
------------------------------------------------------------------------
r35895 | paola | 2016-09-30 03:14:28 -0700 (Fri, 30 Sep 2016) | 2 lines

Fixing build

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35895)
+++ go_inferences.obo	(working copy)
@@ -24200,6 +24200,10 @@
 is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
 
 [Term]
+id: GO:0032391 ! photoreceptor connecting cilium
+is_a: GO:0097458 {is_inferred="true"} ! neuron part
+
+[Term]
 id: GO:0032400 ! melanosome localization
 is_a: GO:0051875 {is_inferred="true"} ! pigment granule localization
 
@@ -30168,10 +30172,6 @@
 is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
 
 [Term]
-id: GO:0035845 ! photoreceptor cell outer segment organization
-is_a: GO:0044782 {is_inferred="true"} ! cilium organization
-
-[Term]
 id: GO:0035846 ! oviduct epithelium development
 is_a: GO:0048608 {is_inferred="true"} ! reproductive structure development
 
@@ -60360,6 +60360,10 @@
 is_a: GO:0044424 {is_inferred="true"} ! intracellular part
 
 [Term]
+id: GO:0097733 ! photoreceptor cell cilium
+is_a: GO:0097458 {is_inferred="true"} ! neuron part
+
+[Term]
 id: GO:0098003 ! viral tail assembly
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
 
@@ -80408,7 +80412,7 @@
 
 [Term]
 id: GO:1903546 ! protein localization to photoreceptor outer segment
-is_a: GO:0097499 {is_inferred="true"} ! protein localization to nonmotile primary cilium
+is_a: GO:0061512 {is_inferred="true"} ! protein localization to cilium
 
 [Term]
 id: GO:1903547 ! regulation of growth hormone activity
@@ -80793,7 +80797,7 @@
 
 [Term]
 id: GO:1903621 ! protein localization to photoreceptor connecting cilium
-is_a: GO:0097499 {is_inferred="true"} ! protein localization to nonmotile primary cilium
+is_a: GO:1904491 {is_inferred="true"} ! protein localization to ciliary transition zone
 
 [Term]
 id: GO:1903622 ! regulation of RNA polymerase III activity
------------------------------------------------------------------------
r35881 | termgenie | 2016-09-29 06:40:31 -0700 (Thu, 29 Sep 2016) | 3 lines

TermGenie commit for user: pf reviewed by dos

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35881)
+++ go_inferences.obo	(working copy)
@@ -89973,10 +89973,45 @@
 is_a: GO:0030031 {is_inferred="true"} ! cell projection assembly
 
 [Term]
+id: GO:1905502 ! acetyl-CoA binding
+is_a: GO:1901681 {is_inferred="true"} ! sulfur compound binding
+
+[Term]
+id: GO:1905503 ! regulation of motile primary cilium assembly
+is_a: GO:1902017 {is_inferred="true"} ! regulation of cilium assembly
+
+[Term]
+id: GO:1905504 ! negative regulation of motile primary cilium assembly
+is_a: GO:1902018 {is_inferred="true"} ! negative regulation of cilium assembly
+is_a: GO:1905503 {is_inferred="true"} ! regulation of motile primary cilium assembly
+
+[Term]
+id: GO:1905505 ! positive regulation of motile primary cilium assembly
+is_a: GO:0045724 {is_inferred="true"} ! positive regulation of cilium assembly
+is_a: GO:1905503 {is_inferred="true"} ! regulation of motile primary cilium assembly
+
+[Term]
 id: GO:1905506 ! gerontoplast stroma
 is_a: GO:0009532 {is_inferred="true"} ! plastid stroma
 
 [Term]
+id: GO:1905507 ! cytoplasmic sequestering of protein involved in mitotic G2 DNA damage checkpoint
+is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
+is_a: GO:1905482 {is_inferred="true"} ! cytoplasmic sequestering of protein involved in G2 DNA damage checkpoint
+
+[Term]
+id: GO:1905510 ! negative regulation of myosin II filament assembly
+is_a: GO:0031333 {is_inferred="true"} ! negative regulation of protein complex assembly
+is_a: GO:0043520 {is_inferred="true"} ! regulation of myosin II filament assembly
+is_a: GO:1904900 {is_inferred="true"} ! negative regulation of myosin II filament organization
+
+[Term]
+id: GO:1905511 ! positive regulation of myosin II filament assembly
+is_a: GO:0031334 {is_inferred="true"} ! positive regulation of protein complex assembly
+is_a: GO:0043520 {is_inferred="true"} ! regulation of myosin II filament assembly
+is_a: GO:1904901 {is_inferred="true"} ! positive regulation of myosin II filament organization
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35876 | paola | 2016-09-29 06:29:52 -0700 (Thu, 29 Sep 2016) | 3 lines

GH NTRs/OTRs: types of cilia #12462 - work in progress - moved ‘kinocilium’ from is_a ‘nonmotile primary cilium’ to is_a ‘9+2 non-motile cilium’.

changes in entailments

------------------------------------------------------------------------
r35873 | paola | 2016-09-29 06:19:23 -0700 (Thu, 29 Sep 2016) | 3 lines

GH NTRs/OTRs: types of cilia #12462 - work in progress - moved ‘ciliary transition zone’ from part_of ‘primary cilium’ to part_of ‘cilium’, which is more correct 

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35874)
+++ go_inferences.obo	(working copy)
@@ -85067,7 +85067,7 @@
 
 [Term]
 id: GO:1904491 ! protein localization to ciliary transition zone
-is_a: GO:0097499 {is_inferred="true"} ! protein localization to nonmotile primary cilium
+is_a: GO:0061512 {is_inferred="true"} ! protein localization to cilium
 
 [Term]
 id: GO:1904492 ! Ac-Asp-Glu binding
------------------------------------------------------------------------
r35872 | paola | 2016-09-29 06:11:32 -0700 (Thu, 29 Sep 2016) | 2 lines

GH NTRs/OTRs: types of cilia #12462 - work in progress - added GO:0097730 non-motile cilium, GO:0097731 9+0 non-motile cilium, GO:0097732 9+2 non-motile cilium

changes in entailments

------------------------------------------------------------------------
r35870 | paola | 2016-09-29 04:47:38 -0700 (Thu, 29 Sep 2016) | 2 lines

GH 'cilium morphogenesis' and 'cilium assembly' #12236 - work in progress - added def. comment to ‘cilium morphogenesis’ terms.

changes in entailments

------------------------------------------------------------------------
r35859 | tberardi | 2016-09-27 13:45:35 -0700 (Tue, 27 Sep 2016) | 1 line

added missing part-of relationship for trichome papilla formation and some new synonyms for GO:0052033

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35859)
+++ go_inferences.obo	(working copy)
@@ -89969,6 +89969,7 @@
 
 [Term]
 id: GO:1905499 ! trichome papilla formation
+is_a: GO:0010927 {is_inferred="true"} ! cellular component assembly involved in morphogenesis
 is_a: GO:0030031 {is_inferred="true"} ! cell projection assembly
 
 [Term]
------------------------------------------------------------------------
r35857 | termgenie | 2016-09-27 13:05:17 -0700 (Tue, 27 Sep 2016) | 2 lines

TermGenie commit for user: tb reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35857)
+++ go_inferences.obo	(working copy)
@@ -89972,6 +89972,10 @@
 is_a: GO:0030031 {is_inferred="true"} ! cell projection assembly
 
 [Term]
+id: GO:1905506 ! gerontoplast stroma
+is_a: GO:0009532 {is_inferred="true"} ! plastid stroma
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35855 | paola | 2016-09-27 07:51:11 -0700 (Tue, 27 Sep 2016) | 3 lines

GH NTRs/OTRs: types of cilia #12462 - work in progress - added has_part links to ‘9+0 motile cilium’ and ‘9+2 motile cilium’.

changes in entailments

------------------------------------------------------------------------
r35853 | paola | 2016-09-27 07:33:52 -0700 (Tue, 27 Sep 2016) | 3 lines

GH NTRs/OTRs: types of cilia #12462 - work in progress - added ‘9+0 motile cilium’ and ‘9+2 motile cilium’; placed ‘sperm flagellum’, Giardia and dinoflagellate flagella terms under the latter.

changes in entailments

------------------------------------------------------------------------
r35851 | paola | 2016-09-27 05:47:06 -0700 (Tue, 27 Sep 2016) | 3 lines

GH NTR/OTR: multiciliation-related classes #12672 - work in progress - added taxon constraint to ‘deuterosome’.

changes in entailments

------------------------------------------------------------------------
r35842 | termgenie | 2016-09-26 17:34:42 -0700 (Mon, 26 Sep 2016) | 2 lines

TermGenie commit for user: tb reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35842)
+++ go_inferences.obo	(working copy)
@@ -89968,6 +89968,10 @@
 is_a: GO:1905496 {is_inferred="true"} ! regulation of triplex DNA binding
 
 [Term]
+id: GO:1905499 ! trichome papilla formation
+is_a: GO:0030031 {is_inferred="true"} ! cell projection assembly
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35840 | tberardi | 2016-09-26 12:53:38 -0700 (Mon, 26 Sep 2016) | 1 line

created new term for cc trichome papilla

changes in entailments

------------------------------------------------------------------------
r35835 | termgenie | 2016-09-26 09:05:04 -0700 (Mon, 26 Sep 2016) | 4 lines

TermGenie commit for user: ans reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35835)
+++ go_inferences.obo	(working copy)
@@ -89940,6 +89940,34 @@
 is_a: GO:2000172 {is_inferred="true"} ! regulation of branching morphogenesis of a nerve
 
 [Term]
+id: GO:1905493 ! regulation of G-quadruplex DNA binding
+is_a: GO:0051101 {is_inferred="true"} ! regulation of DNA binding
+
+[Term]
+id: GO:1905494 ! negative regulation of G-quadruplex DNA binding
+is_a: GO:0043392 {is_inferred="true"} ! negative regulation of DNA binding
+is_a: GO:1905493 {is_inferred="true"} ! regulation of G-quadruplex DNA binding
+
+[Term]
+id: GO:1905495 ! positive regulation of G-quadruplex DNA binding
+is_a: GO:0043388 {is_inferred="true"} ! positive regulation of DNA binding
+is_a: GO:1905493 {is_inferred="true"} ! regulation of G-quadruplex DNA binding
+
+[Term]
+id: GO:1905496 ! regulation of triplex DNA binding
+is_a: GO:0051101 {is_inferred="true"} ! regulation of DNA binding
+
+[Term]
+id: GO:1905497 ! negative regulation of triplex DNA binding
+is_a: GO:0043392 {is_inferred="true"} ! negative regulation of DNA binding
+is_a: GO:1905496 {is_inferred="true"} ! regulation of triplex DNA binding
+
+[Term]
+id: GO:1905498 ! positive regulation of triplex DNA binding
+is_a: GO:0043388 {is_inferred="true"} ! positive regulation of DNA binding
+is_a: GO:1905496 {is_inferred="true"} ! regulation of triplex DNA binding
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35804 | dph | 2016-09-23 13:28:03 -0700 (Fri, 23 Sep 2016) | 2 lines

Trying to fix build by removing redundant lines in the header.

changes in entailments

------------------------------------------------------------------------
r35801 | hjd | 2016-09-23 12:44:17 -0700 (Fri, 23 Sep 2016) | 2 lines

added more plant enzymes 

changes in entailments

------------------------------------------------------------------------
r35799 | termgenie | 2016-09-23 10:33:13 -0700 (Fri, 23 Sep 2016) | 2 lines

TermGenie commit for user: hbye reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35799)
+++ go_inferences.obo	(working copy)
@@ -73358,17 +73358,17 @@
 
 [Term]
 id: GO:1902076 ! regulation of lateral motor column neuron migration
-is_a: GO:2001222 {is_inferred="true"} ! regulation of neuron migration
+is_a: GO:1905483 {is_inferred="true"} ! regulation of motor neuron migration
 
 [Term]
 id: GO:1902077 ! negative regulation of lateral motor column neuron migration
 is_a: GO:1902076 {is_inferred="true"} ! regulation of lateral motor column neuron migration
-is_a: GO:2001223 {is_inferred="true"} ! negative regulation of neuron migration
+is_a: GO:1905484 {is_inferred="true"} ! negative regulation of motor neuron migration
 
 [Term]
 id: GO:1902078 ! positive regulation of lateral motor column neuron migration
 is_a: GO:1902076 {is_inferred="true"} ! regulation of lateral motor column neuron migration
-is_a: GO:2001224 {is_inferred="true"} ! positive regulation of neuron migration
+is_a: GO:1905485 {is_inferred="true"} ! positive regulation of motor neuron migration
 
 [Term]
 id: GO:1902079 ! D-valine catabolic process
@@ -89893,6 +89893,53 @@
 is_a: GO:0051220 {is_inferred="true"} ! cytoplasmic sequestering of protein
 
 [Term]
+id: GO:1905483 ! regulation of motor neuron migration
+is_a: GO:2001222 {is_inferred="true"} ! regulation of neuron migration
+
+[Term]
+id: GO:1905484 ! negative regulation of motor neuron migration
+is_a: GO:1905483 {is_inferred="true"} ! regulation of motor neuron migration
+is_a: GO:2001223 {is_inferred="true"} ! negative regulation of neuron migration
+
+[Term]
+id: GO:1905485 ! positive regulation of motor neuron migration
+is_a: GO:1905483 {is_inferred="true"} ! regulation of motor neuron migration
+is_a: GO:2001224 {is_inferred="true"} ! positive regulation of neuron migration
+
+[Term]
+id: GO:1905486 ! regulation of anterior/posterior axon guidance
+is_a: GO:1902667 {is_inferred="true"} ! regulation of axon guidance
+
+[Term]
+id: GO:1905487 ! negative regulation of anterior/posterior axon guidance
+is_a: GO:1902668 {is_inferred="true"} ! negative regulation of axon guidance
+is_a: GO:1905486 {is_inferred="true"} ! regulation of anterior/posterior axon guidance
+
+[Term]
+id: GO:1905488 ! positive regulation of anterior/posterior axon guidance
+is_a: GO:1902669 {is_inferred="true"} ! positive regulation of axon guidance
+is_a: GO:1905486 {is_inferred="true"} ! regulation of anterior/posterior axon guidance
+
+[Term]
+id: GO:1905489 ! regulation of sensory neuron axon guidance
+is_a: GO:1902667 {is_inferred="true"} ! regulation of axon guidance
+
+[Term]
+id: GO:1905490 ! negative regulation of sensory neuron axon guidance
+is_a: GO:1902668 {is_inferred="true"} ! negative regulation of axon guidance
+is_a: GO:1905489 {is_inferred="true"} ! regulation of sensory neuron axon guidance
+
+[Term]
+id: GO:1905491 ! positive regulation of sensory neuron axon guidance
+is_a: GO:1902669 {is_inferred="true"} ! positive regulation of axon guidance
+is_a: GO:1905489 {is_inferred="true"} ! regulation of sensory neuron axon guidance
+
+[Term]
+id: GO:1905492 ! positive regulation of branching morphogenesis of a nerve
+is_a: GO:0051962 {is_inferred="true"} ! positive regulation of nervous system development
+is_a: GO:2000172 {is_inferred="true"} ! regulation of branching morphogenesis of a nerve
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35790 | paola | 2016-09-23 02:00:16 -0700 (Fri, 23 Sep 2016) | 3 lines

GH NTR/OTR: multiciliation-related classes #12672 - work in progress - added GO:0097727 blepharoplast

changes in entailments

------------------------------------------------------------------------
r35786 | tberardi | 2016-09-22 16:54:48 -0700 (Thu, 22 Sep 2016) | 1 line

GH12668 NTR (then obsolete): triplex DNA unwinding - closed

changes in entailments

------------------------------------------------------------------------
r35783 | termgenie | 2016-09-22 14:18:22 -0700 (Thu, 22 Sep 2016) | 2 lines

TermGenie commit for user: vw reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35783)
+++ go_inferences.obo	(working copy)
@@ -59105,20 +59105,20 @@
 
 [Term]
 id: GO:0090313 ! regulation of protein targeting to membrane
-is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 is_a: GO:1903533 {is_inferred="true"} ! regulation of protein targeting
+is_a: GO:1905475 {is_inferred="true"} ! regulation of protein localization to membrane
 
 [Term]
 id: GO:0090314 ! positive regulation of protein targeting to membrane
-is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 is_a: GO:0090313 {is_inferred="true"} ! regulation of protein targeting to membrane
 is_a: GO:0090316 {is_inferred="true"} ! positive regulation of intracellular protein transport
+is_a: GO:1905477 {is_inferred="true"} ! positive regulation of protein localization to membrane
 
 [Term]
 id: GO:0090315 ! negative regulation of protein targeting to membrane
-is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:0090313 {is_inferred="true"} ! regulation of protein targeting to membrane
 is_a: GO:0090317 {is_inferred="true"} ! negative regulation of intracellular protein transport
+is_a: GO:1905476 {is_inferred="true"} ! negative regulation of protein localization to membrane
 
 [Term]
 id: GO:0090316 ! positive regulation of intracellular protein transport
@@ -66470,6 +66470,7 @@
 id: GO:1900739 ! regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
 is_a: GO:1901028 {is_inferred="true"} ! regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
 is_a: GO:1903747 {is_inferred="true"} ! regulation of establishment of protein localization to mitochondrion
+is_a: GO:1905475 {is_inferred="true"} ! regulation of protein localization to membrane
 
 [Term]
 id: GO:1900740 ! positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
@@ -66476,6 +66477,7 @@
 is_a: GO:1900739 {is_inferred="true"} ! regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
 is_a: GO:1901030 {is_inferred="true"} ! positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
 is_a: GO:1903749 {is_inferred="true"} ! positive regulation of establishment of protein localization to mitochondrion
+is_a: GO:1905477 {is_inferred="true"} ! positive regulation of protein localization to membrane
 
 [Term]
 id: GO:1900741 ! regulation of filamentous growth of a population of unicellular organisms in response to pH
@@ -77286,7 +77288,7 @@
 [Term]
 id: GO:1902897 ! regulation of postsynaptic density protein 95 clustering
 is_a: GO:1901626 {is_inferred="true"} ! regulation of postsynaptic membrane organization
-is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
+is_a: GO:1905475 {is_inferred="true"} ! regulation of protein localization to membrane
 
 [Term]
 id: GO:1902898 ! fatty acid methyl ester metabolic process
@@ -78164,18 +78166,19 @@
 id: GO:1903076 ! regulation of protein localization to plasma membrane
 is_a: GO:1903729 {is_inferred="true"} ! regulation of plasma membrane organization
 is_a: GO:1904375 {is_inferred="true"} ! regulation of protein localization to cell periphery
+is_a: GO:1905475 {is_inferred="true"} ! regulation of protein localization to membrane
 
 [Term]
 id: GO:1903077 ! negative regulation of protein localization to plasma membrane
-is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:1903076 {is_inferred="true"} ! regulation of protein localization to plasma membrane
 is_a: GO:1904376 {is_inferred="true"} ! negative regulation of protein localization to cell periphery
+is_a: GO:1905476 {is_inferred="true"} ! negative regulation of protein localization to membrane
 
 [Term]
 id: GO:1903078 ! positive regulation of protein localization to plasma membrane
-is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 is_a: GO:1903076 {is_inferred="true"} ! regulation of protein localization to plasma membrane
 is_a: GO:1904377 {is_inferred="true"} ! positive regulation of protein localization to cell periphery
+is_a: GO:1905477 {is_inferred="true"} ! positive regulation of protein localization to membrane
 
 [Term]
 id: GO:1903080 ! regulation of C-C chemokine receptor CCR7 signaling pathway
@@ -80502,23 +80505,23 @@
 
 [Term]
 id: GO:1903567 ! regulation of protein localization to ciliary membrane
-is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 is_a: GO:1903564 {is_inferred="true"} ! regulation of protein localization to cilium
 is_a: GO:1904375 {is_inferred="true"} ! regulation of protein localization to cell periphery
+is_a: GO:1905475 {is_inferred="true"} ! regulation of protein localization to membrane
 
 [Term]
 id: GO:1903568 ! negative regulation of protein localization to ciliary membrane
-is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:1903565 {is_inferred="true"} ! negative regulation of protein localization to cilium
 is_a: GO:1903567 {is_inferred="true"} ! regulation of protein localization to ciliary membrane
 is_a: GO:1904376 {is_inferred="true"} ! negative regulation of protein localization to cell periphery
+is_a: GO:1905476 {is_inferred="true"} ! negative regulation of protein localization to membrane
 
 [Term]
 id: GO:1903569 ! positive regulation of protein localization to ciliary membrane
-is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 is_a: GO:1903566 {is_inferred="true"} ! positive regulation of protein localization to cilium
 is_a: GO:1903567 {is_inferred="true"} ! regulation of protein localization to ciliary membrane
 is_a: GO:1904377 {is_inferred="true"} ! positive regulation of protein localization to cell periphery
+is_a: GO:1905477 {is_inferred="true"} ! positive regulation of protein localization to membrane
 
 [Term]
 id: GO:1903570 ! regulation of protein kinase D signaling
@@ -80867,6 +80870,7 @@
 is_a: GO:0034762 {is_inferred="true"} ! regulation of transmembrane transport
 is_a: GO:1903214 {is_inferred="true"} ! regulation of protein targeting to mitochondrion
 is_a: GO:1904589 {is_inferred="true"} ! regulation of protein import
+is_a: GO:1905475 {is_inferred="true"} ! regulation of protein localization to membrane
 
 [Term]
 id: GO:1903637 ! negative regulation of protein import into mitochondrial outer membrane
@@ -80874,6 +80878,7 @@
 is_a: GO:1903215 {is_inferred="true"} ! negative regulation of protein targeting to mitochondrion
 is_a: GO:1903636 {is_inferred="true"} ! regulation of protein import into mitochondrial outer membrane
 is_a: GO:1904590 {is_inferred="true"} ! negative regulation of protein import
+is_a: GO:1905476 {is_inferred="true"} ! negative regulation of protein localization to membrane
 
 [Term]
 id: GO:1903638 ! positive regulation of protein import into mitochondrial outer membrane
@@ -80881,6 +80886,7 @@
 is_a: GO:1903636 {is_inferred="true"} ! regulation of protein import into mitochondrial outer membrane
 is_a: GO:1903955 {is_inferred="true"} ! positive regulation of protein targeting to mitochondrion
 is_a: GO:1904591 {is_inferred="true"} ! positive regulation of protein import
+is_a: GO:1905477 {is_inferred="true"} ! positive regulation of protein localization to membrane
 
 [Term]
 id: GO:1903639 ! regulation of gastrin-induced gastric acid secretion
@@ -82159,20 +82165,17 @@
 
 [Term]
 id: GO:1903909 ! regulation of receptor clustering
-is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
-is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
+is_a: GO:1905475 {is_inferred="true"} ! regulation of protein localization to membrane
 
 [Term]
 id: GO:1903910 ! negative regulation of receptor clustering
-is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
-is_a: GO:1903828 {is_inferred="true"} ! negative regulation of cellular protein localization
 is_a: GO:1903909 {is_inferred="true"} ! regulation of receptor clustering
+is_a: GO:1905476 {is_inferred="true"} ! negative regulation of protein localization to membrane
 
 [Term]
 id: GO:1903911 ! positive regulation of receptor clustering
-is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
-is_a: GO:1903829 {is_inferred="true"} ! positive regulation of cellular protein localization
 is_a: GO:1903909 {is_inferred="true"} ! regulation of receptor clustering
+is_a: GO:1905477 {is_inferred="true"} ! positive regulation of protein localization to membrane
 
 [Term]
 id: GO:1903912 ! negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
@@ -82780,20 +82783,17 @@
 
 [Term]
 id: GO:1904032 ! regulation of t-SNARE clustering
-is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
-is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
+is_a: GO:1905475 {is_inferred="true"} ! regulation of protein localization to membrane
 
 [Term]
 id: GO:1904033 ! negative regulation of t-SNARE clustering
-is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
-is_a: GO:1903828 {is_inferred="true"} ! negative regulation of cellular protein localization
 is_a: GO:1904032 {is_inferred="true"} ! regulation of t-SNARE clustering
+is_a: GO:1905476 {is_inferred="true"} ! negative regulation of protein localization to membrane
 
 [Term]
 id: GO:1904034 ! positive regulation of t-SNARE clustering
-is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
-is_a: GO:1903829 {is_inferred="true"} ! positive regulation of cellular protein localization
 is_a: GO:1904032 {is_inferred="true"} ! regulation of t-SNARE clustering
+is_a: GO:1905477 {is_inferred="true"} ! positive regulation of protein localization to membrane
 
 [Term]
 id: GO:1904035 ! regulation of epithelial cell apoptotic process
@@ -85156,20 +85156,20 @@
 
 [Term]
 id: GO:1904508 ! regulation of protein localization to basolateral plasma membrane
-is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 is_a: GO:1904375 {is_inferred="true"} ! regulation of protein localization to cell periphery
+is_a: GO:1905475 {is_inferred="true"} ! regulation of protein localization to membrane
 
 [Term]
 id: GO:1904509 ! negative regulation of protein localization to basolateral plasma membrane
-is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:1904376 {is_inferred="true"} ! negative regulation of protein localization to cell periphery
 is_a: GO:1904508 {is_inferred="true"} ! regulation of protein localization to basolateral plasma membrane
+is_a: GO:1905476 {is_inferred="true"} ! negative regulation of protein localization to membrane
 
 [Term]
 id: GO:1904510 ! positive regulation of protein localization to basolateral plasma membrane
-is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 is_a: GO:1904377 {is_inferred="true"} ! positive regulation of protein localization to cell periphery
 is_a: GO:1904508 {is_inferred="true"} ! regulation of protein localization to basolateral plasma membrane
+is_a: GO:1905477 {is_inferred="true"} ! positive regulation of protein localization to membrane
 
 [Term]
 id: GO:1904511 ! cytoplasmic microtubule plus-end
@@ -89852,6 +89852,47 @@
 is_a: GO:0044340 {is_inferred="true"} ! canonical Wnt signaling pathway involved in regulation of cell proliferation
 
 [Term]
+id: GO:1905475 ! regulation of protein localization to membrane
+is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
+is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
+
+[Term]
+id: GO:1905476 ! negative regulation of protein localization to membrane
+is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
+is_a: GO:1903828 {is_inferred="true"} ! negative regulation of cellular protein localization
+is_a: GO:1905475 {is_inferred="true"} ! regulation of protein localization to membrane
+
+[Term]
+id: GO:1905477 ! positive regulation of protein localization to membrane
+is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
+is_a: GO:1903829 {is_inferred="true"} ! positive regulation of cellular protein localization
+is_a: GO:1905475 {is_inferred="true"} ! regulation of protein localization to membrane
+
+[Term]
+id: GO:1905478 ! regulation of glutamate-ammonia ligase activity
+is_a: GO:0051340 {is_inferred="true"} ! regulation of ligase activity
+
+[Term]
+id: GO:1905479 ! negative regulation of glutamate-ammonia ligase activity
+is_a: GO:0051352 {is_inferred="true"} ! negative regulation of ligase activity
+is_a: GO:1905478 {is_inferred="true"} ! regulation of glutamate-ammonia ligase activity
+
+[Term]
+id: GO:1905480 ! positive regulation of glutamate-ammonia ligase activity
+is_a: GO:0051351 {is_inferred="true"} ! positive regulation of ligase activity
+is_a: GO:1905478 {is_inferred="true"} ! regulation of glutamate-ammonia ligase activity
+
+[Term]
+id: GO:1905481 ! cytoplasmic sequestering of protein involved in mitotic DNA replication checkpoint
+is_a: GO:0051220 {is_inferred="true"} ! cytoplasmic sequestering of protein
+is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
+
+[Term]
+id: GO:1905482 ! cytoplasmic sequestering of protein involved in G2 DNA damage checkpoint
+is_a: GO:0022402 {is_inferred="true"} ! cell cycle process
+is_a: GO:0051220 {is_inferred="true"} ! cytoplasmic sequestering of protein
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35773 | foulger | 2016-09-22 07:37:39 -0700 (Thu, 22 Sep 2016) | 11 lines

A few tidy-up edits:

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35773)
+++ go_inferences.obo	(working copy)
@@ -73920,15 +73920,18 @@
 
 [Term]
 id: GO:1902186 ! regulation of viral release from host cell
+is_a: GO:0040012 {is_inferred="true"} ! regulation of locomotion
 is_a: GO:1903900 {is_inferred="true"} ! regulation of viral life cycle
 
 [Term]
 id: GO:1902187 ! negative regulation of viral release from host cell
+is_a: GO:0040013 {is_inferred="true"} ! negative regulation of locomotion
 is_a: GO:1902186 {is_inferred="true"} ! regulation of viral release from host cell
 is_a: GO:1903901 {is_inferred="true"} ! negative regulation of viral life cycle
 
 [Term]
 id: GO:1902188 ! positive regulation of viral release from host cell
+is_a: GO:0040017 {is_inferred="true"} ! positive regulation of locomotion
 is_a: GO:1902186 {is_inferred="true"} ! regulation of viral release from host cell
 is_a: GO:1903902 {is_inferred="true"} ! positive regulation of viral life cycle
 
------------------------------------------------------------------------
r35766 | tberardi | 2016-09-21 12:50:44 -0700 (Wed, 21 Sep 2016) | 1 line

GH12670 rename GO:0050139, nicotinate glucosyltransferase activity and create new term - closed

changes in entailments

------------------------------------------------------------------------
r35764 | termgenie | 2016-09-21 09:40:38 -0700 (Wed, 21 Sep 2016) | 2 lines

TermGenie commit for user: bc reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35764)
+++ go_inferences.obo	(working copy)
@@ -89845,6 +89845,10 @@
 is_a: GO:2001162 {is_inferred="true"} ! positive regulation of histone H3-K79 methylation
 
 [Term]
+id: GO:1905474 ! canonical Wnt signaling pathway involved in stem cell proliferation
+is_a: GO:0044340 {is_inferred="true"} ! canonical Wnt signaling pathway involved in regulation of cell proliferation
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35761 | termgenie | 2016-09-21 08:54:04 -0700 (Wed, 21 Sep 2016) | 4 lines

TermGenie commit for user: hbye reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35761)
+++ go_inferences.obo	(working copy)
@@ -89831,6 +89831,20 @@
 is_a: GO:1905468 {is_inferred="true"} ! regulation of clathrin-coated pit assembly
 
 [Term]
+id: GO:1905471 ! regulation of histone H3-K79 dimethylation
+is_a: GO:2001160 {is_inferred="true"} ! regulation of histone H3-K79 methylation
+
+[Term]
+id: GO:1905472 ! negative regulation of histone H3-K79 dimethylation
+is_a: GO:1905471 {is_inferred="true"} ! regulation of histone H3-K79 dimethylation
+is_a: GO:2001161 {is_inferred="true"} ! negative regulation of histone H3-K79 methylation
+
+[Term]
+id: GO:1905473 ! positive regulation of histone H3-K79 dimethylation
+is_a: GO:1905471 {is_inferred="true"} ! regulation of histone H3-K79 dimethylation
+is_a: GO:2001162 {is_inferred="true"} ! positive regulation of histone H3-K79 methylation
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35751 | tberardi | 2016-09-20 16:55:09 -0700 (Tue, 20 Sep 2016) | 1 line

GH12496 obsolete: multicellular structure septum development - closed

changes in entailments

------------------------------------------------------------------------
r35749 | tberardi | 2016-09-20 16:41:37 -0700 (Tue, 20 Sep 2016) | 1 line

GH12668 NTR: triplex DNA unwinding - closed

changes in entailments

------------------------------------------------------------------------
r35747 | tberardi | 2016-09-20 16:28:03 -0700 (Tue, 20 Sep 2016) | 1 line

GH12666 MP GO:0071851 mitotic G1 cell cycle arrest in response to nitrogen starvation - closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35747)
+++ go_inferences.obo	(working copy)
@@ -81150,6 +81150,10 @@
 is_a: GO:0044690 {is_inferred="true"} ! methionine import
 
 [Term]
+id: GO:1903693 ! regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation
+is_a: GO:0007346 {is_inferred="true"} ! regulation of mitotic cell cycle
+
+[Term]
 id: GO:1903694 ! positive regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation
 is_a: GO:0071158 {is_inferred="true"} ! positive regulation of cell cycle arrest
 is_a: GO:1903693 {is_inferred="true"} ! regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation
------------------------------------------------------------------------
r35745 | tberardi | 2016-09-20 16:18:07 -0700 (Tue, 20 Sep 2016) | 1 line

GH12669 Rename "thrombin receptor activity" to "thrombin-activated receptor activity" and change def - closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35745)
+++ go_inferences.obo	(working copy)
@@ -52203,18 +52203,18 @@
 is_a: GO:0030246 {is_inferred="true"} ! carbohydrate binding
 
 [Term]
-id: GO:0070494 ! regulation of thrombin receptor signaling pathway
+id: GO:0070494 ! regulation of thrombin-activated receptor signaling pathway
 is_a: GO:0008277 {is_inferred="true"} ! regulation of G-protein coupled receptor protein signaling pathway
 
 [Term]
-id: GO:0070495 ! negative regulation of thrombin receptor signaling pathway
+id: GO:0070495 ! negative regulation of thrombin-activated receptor signaling pathway
 is_a: GO:0045744 {is_inferred="true"} ! negative regulation of G-protein coupled receptor protein signaling pathway
-is_a: GO:0070494 {is_inferred="true"} ! regulation of thrombin receptor signaling pathway
+is_a: GO:0070494 {is_inferred="true"} ! regulation of thrombin-activated receptor signaling pathway
 
 [Term]
-id: GO:0070496 ! positive regulation of thrombin receptor signaling pathway
+id: GO:0070496 ! positive regulation of thrombin-activated receptor signaling pathway
 is_a: GO:0045745 {is_inferred="true"} ! positive regulation of G-protein coupled receptor protein signaling pathway
-is_a: GO:0070494 {is_inferred="true"} ! regulation of thrombin receptor signaling pathway
+is_a: GO:0070494 {is_inferred="true"} ! regulation of thrombin-activated receptor signaling pathway
 
 [Term]
 id: GO:0070499 ! exosporium assembly
------------------------------------------------------------------------
r35743 | termgenie | 2016-09-20 10:58:29 -0700 (Tue, 20 Sep 2016) | 4 lines

TermGenie commit for user: bf reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35743)
+++ go_inferences.obo	(working copy)
@@ -89811,6 +89811,22 @@
 is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
 
 [Term]
+id: GO:1905468 ! regulation of clathrin-coated pit assembly
+is_a: GO:0044087 {is_inferred="true"} ! regulation of cellular component biogenesis
+is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
+
+[Term]
+id: GO:1905469 ! negative regulation of clathrin-coated pit assembly
+is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
+is_a: GO:1905468 {is_inferred="true"} ! regulation of clathrin-coated pit assembly
+
+[Term]
+id: GO:1905470 ! positive regulation of clathrin-coated pit assembly
+is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
+is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
+is_a: GO:1905468 {is_inferred="true"} ! regulation of clathrin-coated pit assembly
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35715 | termgenie | 2016-09-19 09:23:26 -0700 (Mon, 19 Sep 2016) | 4 lines

TermGenie commit for user: ans reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35715)
+++ go_inferences.obo	(working copy)
@@ -75179,9 +75179,9 @@
 
 [Term]
 id: GO:1902449 ! regulation of ATP-dependent DNA helicase activity
-is_a: GO:0033044 {is_inferred="true"} ! regulation of chromosome organization
 is_a: GO:0043462 {is_inferred="true"} ! regulation of ATPase activity
 is_a: GO:0051095 {is_inferred="true"} ! regulation of helicase activity
+is_a: GO:1905462 {is_inferred="true"} ! regulation of DNA duplex unwinding
 
 [Term]
 id: GO:1902450 ! negative regulation of ATP-dependent DNA helicase activity
@@ -75188,7 +75188,7 @@
 is_a: GO:0032780 {is_inferred="true"} ! negative regulation of ATPase activity
 is_a: GO:0051097 {is_inferred="true"} ! negative regulation of helicase activity
 is_a: GO:1902449 {is_inferred="true"} ! regulation of ATP-dependent DNA helicase activity
-is_a: GO:2001251 {is_inferred="true"} ! negative regulation of chromosome organization
+is_a: GO:1905463 {is_inferred="true"} ! negative regulation of DNA duplex unwinding
 
 [Term]
 id: GO:1902451 ! positive regulation of ATP-dependent DNA helicase activity
@@ -75195,7 +75195,7 @@
 is_a: GO:0032781 {is_inferred="true"} ! positive regulation of ATPase activity
 is_a: GO:0051096 {is_inferred="true"} ! positive regulation of helicase activity
 is_a: GO:1902449 {is_inferred="true"} ! regulation of ATP-dependent DNA helicase activity
-is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
+is_a: GO:1905464 {is_inferred="true"} ! positive regulation of DNA duplex unwinding
 
 [Term]
 id: GO:1902455 ! negative regulation of stem cell population maintenance
@@ -89769,6 +89769,48 @@
 is_a: GO:1905456 {is_inferred="true"} ! regulation of lymphoid progenitor cell differentiation
 
 [Term]
+id: GO:1905459 ! regulation of vascular associated smooth muscle cell apoptotic process
+is_a: GO:0034391 {is_inferred="true"} ! regulation of smooth muscle cell apoptotic process
+
+[Term]
+id: GO:1905460 ! negative regulation of vascular associated smooth muscle cell apoptotic process
+is_a: GO:0034392 {is_inferred="true"} ! negative regulation of smooth muscle cell apoptotic process
+is_a: GO:1905459 {is_inferred="true"} ! regulation of vascular associated smooth muscle cell apoptotic process
+
+[Term]
+id: GO:1905461 ! positive regulation of vascular associated smooth muscle cell apoptotic process
+is_a: GO:0034393 {is_inferred="true"} ! positive regulation of smooth muscle cell apoptotic process
+is_a: GO:1905459 {is_inferred="true"} ! regulation of vascular associated smooth muscle cell apoptotic process
+
+[Term]
+id: GO:1905462 ! regulation of DNA duplex unwinding
+is_a: GO:0033044 {is_inferred="true"} ! regulation of chromosome organization
+
+[Term]
+id: GO:1905463 ! negative regulation of DNA duplex unwinding
+is_a: GO:1905462 {is_inferred="true"} ! regulation of DNA duplex unwinding
+is_a: GO:2001251 {is_inferred="true"} ! negative regulation of chromosome organization
+
+[Term]
+id: GO:1905464 ! positive regulation of DNA duplex unwinding
+is_a: GO:1905462 {is_inferred="true"} ! regulation of DNA duplex unwinding
+is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
+
+[Term]
+id: GO:1905465 ! regulation of G-quadruplex DNA unwinding
+is_a: GO:0033044 {is_inferred="true"} ! regulation of chromosome organization
+
+[Term]
+id: GO:1905466 ! negative regulation of G-quadruplex DNA unwinding
+is_a: GO:1905465 {is_inferred="true"} ! regulation of G-quadruplex DNA unwinding
+is_a: GO:2001251 {is_inferred="true"} ! negative regulation of chromosome organization
+
+[Term]
+id: GO:1905467 ! positive regulation of G-quadruplex DNA unwinding
+is_a: GO:1905465 {is_inferred="true"} ! regulation of G-quadruplex DNA unwinding
+is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35711 | paola | 2016-09-19 09:13:54 -0700 (Mon, 19 Sep 2016) | 3 lines

GH comment in: lysosomal protein catabolic process term #12663 - closed - edited comment.

changes in entailments

------------------------------------------------------------------------
r35625 | paola | 2016-09-19 01:23:40 -0700 (Mon, 19 Sep 2016) | 3 lines

GH New term for LEM domain #12664 - closed - added GO:0097726 LEM domain binding

changes in entailments

------------------------------------------------------------------------
r35609 | dph | 2016-09-17 07:09:44 -0700 (Sat, 17 Sep 2016) | 2 lines

GH12653-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35609)
+++ go_inferences.obo	(working copy)
@@ -42630,6 +42630,11 @@
 is_a: GO:0048308 {is_inferred="true"} ! organelle inheritance
 
 [Term]
+id: GO:0048315 ! conidium formation
+is_a: GO:0003006 {is_inferred="true"} ! developmental process involved in reproduction
+is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+
+[Term]
 id: GO:0048316 ! seed development
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
@@ -51201,6 +51206,11 @@
 is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
 [Term]
+id: GO:0061794 ! conidium development
+is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0048837 {is_inferred="true"} ! sorus development
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
@@ -57290,19 +57300,32 @@
 [Term]
 id: GO:0075306 ! regulation of conidium formation
 is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
+is_a: GO:0031156 {is_inferred="true"} ! regulation of sorocarp development
 is_a: GO:0034305 {is_inferred="true"} ! regulation of asexual sporulation
+is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
+is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
 
 [Term]
 id: GO:0075307 ! positive regulation of conidium formation
+is_a: GO:0010647 {is_inferred="true"} ! positive regulation of cell communication
+is_a: GO:0010720 {is_inferred="true"} ! positive regulation of cell development
+is_a: GO:0032109 {is_inferred="true"} ! positive regulation of response to nutrient levels
 is_a: GO:0043938 {is_inferred="true"} ! positive regulation of sporulation
+is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:0075306 {is_inferred="true"} ! regulation of conidium formation
 is_a: GO:1903666 {is_inferred="true"} ! positive regulation of asexual reproduction
+is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
 
 [Term]
 id: GO:0075308 ! negative regulation of conidium formation
+is_a: GO:0010648 {is_inferred="true"} ! negative regulation of cell communication
+is_a: GO:0010721 {is_inferred="true"} ! negative regulation of cell development
+is_a: GO:0032108 {is_inferred="true"} ! negative regulation of response to nutrient levels
 is_a: GO:0043939 {is_inferred="true"} ! negative regulation of sporulation
+is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:0075306 {is_inferred="true"} ! regulation of conidium formation
 is_a: GO:1903665 {is_inferred="true"} ! negative regulation of asexual reproduction
+is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
 
 [Term]
 id: GO:0075310 ! regulation of sporangium development
------------------------------------------------------------------------
r35581 | termgenie | 2016-09-16 05:53:39 -0700 (Fri, 16 Sep 2016) | 7 lines

TermGenie commit for user: rz reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35581)
+++ go_inferences.obo	(working copy)
@@ -89667,6 +89667,20 @@
 is_a: GO:1905441 {is_inferred="true"} ! response to chondroitin 4'-sulfate
 
 [Term]
+id: GO:1905443 ! regulation of clathrin coat assembly
+is_a: GO:0043254 {is_inferred="true"} ! regulation of protein complex assembly
+
+[Term]
+id: GO:1905444 ! negative regulation of clathrin coat assembly
+is_a: GO:0031333 {is_inferred="true"} ! negative regulation of protein complex assembly
+is_a: GO:1905443 {is_inferred="true"} ! regulation of clathrin coat assembly
+
+[Term]
+id: GO:1905445 ! positive regulation of clathrin coat assembly
+is_a: GO:0031334 {is_inferred="true"} ! positive regulation of protein complex assembly
+is_a: GO:1905443 {is_inferred="true"} ! regulation of clathrin coat assembly
+
+[Term]
 id: GO:1905446 ! regulation of mitochondrial ATP synthesis coupled electron transport
 is_a: GO:0002082 {is_inferred="true"} ! regulation of oxidative phosphorylation
 is_a: GO:0043457 {is_inferred="true"} ! regulation of cellular respiration
@@ -89684,6 +89698,54 @@
 is_a: GO:1905446 {is_inferred="true"} ! regulation of mitochondrial ATP synthesis coupled electron transport
 
 [Term]
+id: GO:1905449 ! regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
+is_a: GO:0002697 {is_inferred="true"} ! regulation of immune effector process
+is_a: GO:0050764 {is_inferred="true"} ! regulation of phagocytosis
+is_a: GO:0060368 {is_inferred="true"} ! regulation of Fc receptor mediated stimulatory signaling pathway
+
+[Term]
+id: GO:1905450 ! negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
+is_a: GO:0002698 {is_inferred="true"} ! negative regulation of immune effector process
+is_a: GO:0009968 {is_inferred="true"} ! negative regulation of signal transduction
+is_a: GO:0050765 {is_inferred="true"} ! negative regulation of phagocytosis
+is_a: GO:1905449 {is_inferred="true"} ! regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
+
+[Term]
+id: GO:1905451 ! positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
+is_a: GO:0002699 {is_inferred="true"} ! positive regulation of immune effector process
+is_a: GO:0050766 {is_inferred="true"} ! positive regulation of phagocytosis
+is_a: GO:0060369 {is_inferred="true"} ! positive regulation of Fc receptor mediated stimulatory signaling pathway
+is_a: GO:1905449 {is_inferred="true"} ! regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
+
+[Term]
+id: GO:1905453 ! regulation of myeloid progenitor cell differentiation
+is_a: GO:1901532 {is_inferred="true"} ! regulation of hematopoietic progenitor cell differentiation
+
+[Term]
+id: GO:1905454 ! negative regulation of myeloid progenitor cell differentiation
+is_a: GO:1901533 {is_inferred="true"} ! negative regulation of hematopoietic progenitor cell differentiation
+is_a: GO:1905453 {is_inferred="true"} ! regulation of myeloid progenitor cell differentiation
+
+[Term]
+id: GO:1905455 ! positive regulation of myeloid progenitor cell differentiation
+is_a: GO:1901534 {is_inferred="true"} ! positive regulation of hematopoietic progenitor cell differentiation
+is_a: GO:1905453 {is_inferred="true"} ! regulation of myeloid progenitor cell differentiation
+
+[Term]
+id: GO:1905456 ! regulation of lymphoid progenitor cell differentiation
+is_a: GO:1901532 {is_inferred="true"} ! regulation of hematopoietic progenitor cell differentiation
+
+[Term]
+id: GO:1905457 ! negative regulation of lymphoid progenitor cell differentiation
+is_a: GO:1901533 {is_inferred="true"} ! negative regulation of hematopoietic progenitor cell differentiation
+is_a: GO:1905456 {is_inferred="true"} ! regulation of lymphoid progenitor cell differentiation
+
+[Term]
+id: GO:1905458 ! positive regulation of lymphoid progenitor cell differentiation
+is_a: GO:1901534 {is_inferred="true"} ! positive regulation of hematopoietic progenitor cell differentiation
+is_a: GO:1905456 {is_inferred="true"} ! regulation of lymphoid progenitor cell differentiation
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
@@ -91568,18 +91630,18 @@
 [Term]
 id: GO:2000174 ! regulation of pro-T cell differentiation
 is_a: GO:0045580 {is_inferred="true"} ! regulation of T cell differentiation
-is_a: GO:1901532 {is_inferred="true"} ! regulation of hematopoietic progenitor cell differentiation
+is_a: GO:1905456 {is_inferred="true"} ! regulation of lymphoid progenitor cell differentiation
 
 [Term]
 id: GO:2000175 ! negative regulation of pro-T cell differentiation
 is_a: GO:0045581 {is_inferred="true"} ! negative regulation of T cell differentiation
-is_a: GO:1901533 {is_inferred="true"} ! negative regulation of hematopoietic progenitor cell differentiation
+is_a: GO:1905457 {is_inferred="true"} ! negative regulation of lymphoid progenitor cell differentiation
 is_a: GO:2000174 {is_inferred="true"} ! regulation of pro-T cell differentiation
 
 [Term]
 id: GO:2000176 ! positive regulation of pro-T cell differentiation
 is_a: GO:0045582 {is_inferred="true"} ! positive regulation of T cell differentiation
-is_a: GO:1901534 {is_inferred="true"} ! positive regulation of hematopoietic progenitor cell differentiation
+is_a: GO:1905458 {is_inferred="true"} ! positive regulation of lymphoid progenitor cell differentiation
 is_a: GO:2000174 {is_inferred="true"} ! regulation of pro-T cell differentiation
 
 [Term]
@@ -95648,16 +95710,16 @@
 
 [Term]
 id: GO:2000973 ! regulation of pro-B cell differentiation
-is_a: GO:1901532 {is_inferred="true"} ! regulation of hematopoietic progenitor cell differentiation
+is_a: GO:1905456 {is_inferred="true"} ! regulation of lymphoid progenitor cell differentiation
 
 [Term]
 id: GO:2000974 ! negative regulation of pro-B cell differentiation
-is_a: GO:1901533 {is_inferred="true"} ! negative regulation of hematopoietic progenitor cell differentiation
+is_a: GO:1905457 {is_inferred="true"} ! negative regulation of lymphoid progenitor cell differentiation
 is_a: GO:2000973 {is_inferred="true"} ! regulation of pro-B cell differentiation
 
 [Term]
 id: GO:2000975 ! positive regulation of pro-B cell differentiation
-is_a: GO:1901534 {is_inferred="true"} ! positive regulation of hematopoietic progenitor cell differentiation
+is_a: GO:1905458 {is_inferred="true"} ! positive regulation of lymphoid progenitor cell differentiation
 is_a: GO:2000973 {is_inferred="true"} ! regulation of pro-B cell differentiation
 
 [Term]
------------------------------------------------------------------------
r35570 | termgenie | 2016-09-15 12:01:32 -0700 (Thu, 15 Sep 2016) | 4 lines

TermGenie commit for user: dph reviewed by dph

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35570)
+++ go_inferences.obo	(working copy)
@@ -77553,20 +77553,17 @@
 
 [Term]
 id: GO:1902956 ! regulation of mitochondrial electron transport, NADH to ubiquinone
-is_a: GO:0002082 {is_inferred="true"} ! regulation of oxidative phosphorylation
-is_a: GO:0043457 {is_inferred="true"} ! regulation of cellular respiration
+is_a: GO:1905446 {is_inferred="true"} ! regulation of mitochondrial ATP synthesis coupled electron transport
 
 [Term]
 id: GO:1902957 ! negative regulation of mitochondrial electron transport, NADH to ubiquinone
-is_a: GO:0090324 {is_inferred="true"} ! negative regulation of oxidative phosphorylation
-is_a: GO:1901856 {is_inferred="true"} ! negative regulation of cellular respiration
 is_a: GO:1902956 {is_inferred="true"} ! regulation of mitochondrial electron transport, NADH to ubiquinone
+is_a: GO:1905447 {is_inferred="true"} ! negative regulation of mitochondrial ATP synthesis coupled electron transport
 
 [Term]
 id: GO:1902958 ! positive regulation of mitochondrial electron transport, NADH to ubiquinone
-is_a: GO:1901857 {is_inferred="true"} ! positive regulation of cellular respiration
 is_a: GO:1902956 {is_inferred="true"} ! regulation of mitochondrial electron transport, NADH to ubiquinone
-is_a: GO:1903862 {is_inferred="true"} ! positive regulation of oxidative phosphorylation
+is_a: GO:1905448 {is_inferred="true"} ! positive regulation of mitochondrial ATP synthesis coupled electron transport
 
 [Term]
 id: GO:1902959 ! regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
@@ -89649,23 +89646,44 @@
 
 [Term]
 id: GO:1905439 ! response to chondroitin 6'-sulfate
-is_a: GO:0050896 {is_inferred="true"} ! response to stimulus
+is_a: GO:0010243 {is_inferred="true"} ! response to organonitrogen compound
+is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
 [Term]
 id: GO:1905440 ! cellular response to chondroitin 6'-sulfate
-is_a: GO:0070887 {is_inferred="true"} ! cellular response to chemical stimulus
+is_a: GO:0071417 {is_inferred="true"} ! cellular response to organonitrogen compound
+is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
 is_a: GO:1905439 {is_inferred="true"} ! response to chondroitin 6'-sulfate
 
 [Term]
 id: GO:1905441 ! response to chondroitin 4'-sulfate
-is_a: GO:0050896 {is_inferred="true"} ! response to stimulus
+is_a: GO:0010243 {is_inferred="true"} ! response to organonitrogen compound
+is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
 [Term]
 id: GO:1905442 ! cellular response to chondroitin 4'-sulfate
-is_a: GO:0070887 {is_inferred="true"} ! cellular response to chemical stimulus
+is_a: GO:0071417 {is_inferred="true"} ! cellular response to organonitrogen compound
+is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
 is_a: GO:1905441 {is_inferred="true"} ! response to chondroitin 4'-sulfate
 
 [Term]
+id: GO:1905446 ! regulation of mitochondrial ATP synthesis coupled electron transport
+is_a: GO:0002082 {is_inferred="true"} ! regulation of oxidative phosphorylation
+is_a: GO:0043457 {is_inferred="true"} ! regulation of cellular respiration
+
+[Term]
+id: GO:1905447 ! negative regulation of mitochondrial ATP synthesis coupled electron transport
+is_a: GO:0090324 {is_inferred="true"} ! negative regulation of oxidative phosphorylation
+is_a: GO:1901856 {is_inferred="true"} ! negative regulation of cellular respiration
+is_a: GO:1905446 {is_inferred="true"} ! regulation of mitochondrial ATP synthesis coupled electron transport
+
+[Term]
+id: GO:1905448 ! positive regulation of mitochondrial ATP synthesis coupled electron transport
+is_a: GO:1901857 {is_inferred="true"} ! positive regulation of cellular respiration
+is_a: GO:1903862 {is_inferred="true"} ! positive regulation of oxidative phosphorylation
+is_a: GO:1905446 {is_inferred="true"} ! regulation of mitochondrial ATP synthesis coupled electron transport
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35557 | paola | 2016-09-15 03:45:10 -0700 (Thu, 15 Sep 2016) | 3 lines

GH NTR: histone H3-K79 dimethylation #12661 - closed - added GO:0097725 histone H3-K79 dimethylation

changes in entailments

------------------------------------------------------------------------
r35550 | termgenie | 2016-09-14 12:59:37 -0700 (Wed, 14 Sep 2016) | 5 lines

TermGenie commit for user: cvs reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35550)
+++ go_inferences.obo	(working copy)
@@ -87273,7 +87273,7 @@
 [Term]
 id: GO:1904955 ! planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation
 is_a: GO:0060071 {is_inferred="true"} ! Wnt signaling pathway, planar cell polarity pathway
-is_a: GO:1904953 {is_inferred="true"} ! Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation
+is_a: GO:1905438 {is_inferred="true"} ! non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation
 
 [Term]
 id: GO:1904956 ! regulation of midbrain dopaminergic neuron differentiation
@@ -89629,6 +89629,43 @@
 is_a: GO:1905432 {is_inferred="true"} ! regulation of retrograde trans-synaptic signaling by neuropeptide
 
 [Term]
+id: GO:1905435 ! regulation of histone H3-K4 trimethylation
+is_a: GO:0051569 {is_inferred="true"} ! regulation of histone H3-K4 methylation
+
+[Term]
+id: GO:1905436 ! negative regulation of histone H3-K4 trimethylation
+is_a: GO:0051572 {is_inferred="true"} ! negative regulation of histone H3-K4 methylation
+is_a: GO:1905435 {is_inferred="true"} ! regulation of histone H3-K4 trimethylation
+
+[Term]
+id: GO:1905437 ! positive regulation of histone H3-K4 trimethylation
+is_a: GO:0051571 {is_inferred="true"} ! positive regulation of histone H3-K4 methylation
+is_a: GO:1905435 {is_inferred="true"} ! regulation of histone H3-K4 trimethylation
+
+[Term]
+id: GO:1905438 ! non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation
+is_a: GO:0035567 {is_inferred="true"} ! non-canonical Wnt signaling pathway
+is_a: GO:1904953 {is_inferred="true"} ! Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation
+
+[Term]
+id: GO:1905439 ! response to chondroitin 6'-sulfate
+is_a: GO:0050896 {is_inferred="true"} ! response to stimulus
+
+[Term]
+id: GO:1905440 ! cellular response to chondroitin 6'-sulfate
+is_a: GO:0070887 {is_inferred="true"} ! cellular response to chemical stimulus
+is_a: GO:1905439 {is_inferred="true"} ! response to chondroitin 6'-sulfate
+
+[Term]
+id: GO:1905441 ! response to chondroitin 4'-sulfate
+is_a: GO:0050896 {is_inferred="true"} ! response to stimulus
+
+[Term]
+id: GO:1905442 ! cellular response to chondroitin 4'-sulfate
+is_a: GO:0070887 {is_inferred="true"} ! cellular response to chemical stimulus
+is_a: GO:1905441 {is_inferred="true"} ! response to chondroitin 4'-sulfate
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35541 | dph | 2016-09-14 06:29:22 -0700 (Wed, 14 Sep 2016) | 2 lines

Removed part of relation between epithelial to mesenchymal transition and mesenchymal cell development.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35541)
+++ go_inferences.obo	(working copy)
@@ -12863,19 +12863,19 @@
 
 [Term]
 id: GO:0010717 ! regulation of epithelial to mesenchymal transition
-is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
+is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
 is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
 
 [Term]
 id: GO:0010718 ! positive regulation of epithelial to mesenchymal transition
 is_a: GO:0010717 {is_inferred="true"} ! regulation of epithelial to mesenchymal transition
-is_a: GO:0010720 {is_inferred="true"} ! positive regulation of cell development
+is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 
 [Term]
 id: GO:0010719 ! negative regulation of epithelial to mesenchymal transition
 is_a: GO:0010717 {is_inferred="true"} ! regulation of epithelial to mesenchymal transition
-is_a: GO:0010721 {is_inferred="true"} ! negative regulation of cell development
+is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 
 [Term]
------------------------------------------------------------------------
r35539 | termgenie | 2016-09-14 06:13:22 -0700 (Wed, 14 Sep 2016) | 4 lines

TermGenie commit for user: bf reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35539)
+++ go_inferences.obo	(working copy)
@@ -89612,6 +89612,23 @@
 is_a: GO:0015833 {is_inferred="true"} ! peptide transport
 
 [Term]
+id: GO:1905432 ! regulation of retrograde trans-synaptic signaling by neuropeptide
+is_a: GO:0010646 {is_inferred="true"} ! regulation of cell communication
+is_a: GO:0023051 {is_inferred="true"} ! regulation of signaling
+
+[Term]
+id: GO:1905433 ! negative regulation of retrograde trans-synaptic signaling by neuropeptide
+is_a: GO:0010648 {is_inferred="true"} ! negative regulation of cell communication
+is_a: GO:0023057 {is_inferred="true"} ! negative regulation of signaling
+is_a: GO:1905432 {is_inferred="true"} ! regulation of retrograde trans-synaptic signaling by neuropeptide
+
+[Term]
+id: GO:1905434 ! positive regulation of retrograde trans-synaptic signaling by neuropeptide
+is_a: GO:0010647 {is_inferred="true"} ! positive regulation of cell communication
+is_a: GO:0023056 {is_inferred="true"} ! positive regulation of signaling
+is_a: GO:1905432 {is_inferred="true"} ! regulation of retrograde trans-synaptic signaling by neuropeptide
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35537 | paola | 2016-09-14 05:04:49 -0700 (Wed, 14 Sep 2016) | 3 lines

GH inconsistencies in TM transport function term names #12587 - closed - see ticket for details.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35537)
+++ go_inferences.obo	(working copy)
@@ -15021,7 +15021,7 @@
 is_a: GO:0072509 {is_inferred="true"} ! divalent inorganic cation transmembrane transporter activity
 
 [Term]
-id: GO:0015415 ! phosphate ion transmembrane-transporting ATPase activity
+id: GO:0015415 ! ATPase-coupled phosphate ion transmembrane transporter activity
 is_a: GO:0015114 {is_inferred="true"} ! phosphate ion transmembrane transporter activity
 
 [Term]
@@ -69112,7 +69112,7 @@
 is_a: GO:0015103 {is_inferred="true"} ! inorganic anion transmembrane transporter activity
 
 [Term]
-id: GO:1901238 ! tungstate transmembrane-transporting ATPase activity
+id: GO:1901238 ! ATPase-coupled tungstate transmembrane transporter activity
 is_a: GO:0042626 {is_inferred="true"} ! ATPase activity, coupled to transmembrane movement of substances
 is_a: GO:1901237 {is_inferred="true"} ! tungstate transmembrane transporter activity
 
@@ -69130,7 +69130,7 @@
 is_a: GO:1901505 {is_inferred="true"} ! carbohydrate derivative transporter activity
 
 [Term]
-id: GO:1901243 ! methionine transmembrane-transporting ATPase activity
+id: GO:1901243 ! ATPase-coupled methionine transmembrane transporter activity
 is_a: GO:0042626 {is_inferred="true"} ! ATPase activity, coupled to transmembrane movement of substances
 is_a: GO:0043865 {is_inferred="true"} ! methionine transmembrane transporter activity
 
@@ -89609,7 +89609,7 @@
 
 [Term]
 id: GO:1905431 ! microcystin transport
-is_a: GO:0006810 {is_inferred="true"} ! transport
+is_a: GO:0015833 {is_inferred="true"} ! peptide transport
 
 [Term]
 id: GO:1990000 ! amyloid fibril formation
------------------------------------------------------------------------
r35528 | termgenie | 2016-09-14 00:39:41 -0700 (Wed, 14 Sep 2016) | 2 lines

TermGenie commit for user: cvs reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35528)
+++ go_inferences.obo	(working copy)
@@ -89608,6 +89608,10 @@
 is_a: GO:1905429 {is_inferred="true"} ! response to glycine
 
 [Term]
+id: GO:1905431 ! microcystin transport
+is_a: GO:0006810 {is_inferred="true"} ! transport
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35524 | davidos | 2016-09-13 13:45:33 -0700 (Tue, 13 Sep 2016) | 1 line

Fixing cause of inconsistency in presence of complete Uberon import. Also added <retrograde trans-synaptic signaling by neuropeptide>

changes in entailments

------------------------------------------------------------------------
r35524 | davidos | 2016-09-13 13:45:33 -0700 (Tue, 13 Sep 2016) | 1 line

Fixing cause of inconsistency in presence of complete Uberon import. Also added <retrograde trans-synaptic signaling by neuropeptide>

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35524)
+++ go_inferences.obo	(working copy)
@@ -61917,6 +61917,11 @@
 is_a: GO:0044445 {is_inferred="true"} ! cytosolic part
 
 [Term]
+id: GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide
+is_a: GO:0098917 {is_inferred="true"} ! retrograde trans-synaptic signaling
+is_a: GO:0099540 {is_inferred="true"} ! trans-synaptic signaling by neuropeptide
+
+[Term]
 id: GO:0099400 ! caveola neck
 is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
 
@@ -62051,6 +62056,7 @@
 
 [Term]
 id: GO:0099552 ! trans-synaptic signaling by lipid, modulating synaptic transmission
+is_a: GO:0099541 {is_inferred="true"} ! trans-synaptic signaling by lipid
 is_a: GO:0099550 {is_inferred="true"} ! trans-synaptic signalling, modulating synaptic transmission
 
 [Term]
------------------------------------------------------------------------
r35522 | dph | 2016-09-13 13:04:43 -0700 (Tue, 13 Sep 2016) | 2 lines

GH12448-closed

changes in entailments

------------------------------------------------------------------------
r35520 | dph | 2016-09-13 12:52:32 -0700 (Tue, 13 Sep 2016) | 2 lines

GH12466-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35520)
+++ go_inferences.obo	(working copy)
@@ -47725,7 +47725,6 @@
 
 [Term]
 id: GO:0060049 ! regulation of protein glycosylation
-is_a: GO:0006109 {is_inferred="true"} ! regulation of carbohydrate metabolic process
 is_a: GO:0010559 {is_inferred="true"} ! regulation of glycoprotein biosynthetic process
 is_a: GO:0031399 {is_inferred="true"} ! regulation of protein modification process
 
@@ -47732,13 +47731,11 @@
 [Term]
 id: GO:0060050 ! positive regulation of protein glycosylation
 is_a: GO:0031401 {is_inferred="true"} ! positive regulation of protein modification process
-is_a: GO:0045913 {is_inferred="true"} ! positive regulation of carbohydrate metabolic process
 is_a: GO:0060049 {is_inferred="true"} ! regulation of protein glycosylation
 
 [Term]
 id: GO:0060051 ! negative regulation of protein glycosylation
 is_a: GO:0031400 {is_inferred="true"} ! negative regulation of protein modification process
-is_a: GO:0045912 {is_inferred="true"} ! negative regulation of carbohydrate metabolic process
 is_a: GO:0060049 {is_inferred="true"} ! regulation of protein glycosylation
 
 [Term]
------------------------------------------------------------------------
r35518 | dph | 2016-09-13 12:27:00 -0700 (Tue, 13 Sep 2016) | 2 lines

Modified the def of mitotic cytokinesis checkpoint and added it as a child of negative reegulation of G2/M transition of mitotic cell cycle.

changes in entailments

------------------------------------------------------------------------
r35515 | dph | 2016-09-13 11:47:26 -0700 (Tue, 13 Sep 2016) | 2 lines

GH12477-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35515)
+++ go_inferences.obo	(working copy)
@@ -4553,23 +4553,23 @@
 
 [Term]
 id: GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis
+is_a: GO:0035850 {is_inferred="true"} ! epithelial cell differentiation involved in kidney development
 is_a: GO:0060231 {is_inferred="true"} ! mesenchymal to epithelial transition
+is_a: GO:0072202 {is_inferred="true"} ! cell differentiation involved in metanephros development
 
 [Term]
 id: GO:0003339 ! regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
-is_a: GO:0010769 {is_inferred="true"} ! regulation of cell morphogenesis involved in differentiation
-is_a: GO:0030856 {is_inferred="true"} ! regulation of epithelial cell differentiation
 is_a: GO:0072215 {is_inferred="true"} ! regulation of metanephros development
 is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 is_a: GO:2000027 {is_inferred="true"} ! regulation of organ morphogenesis
+is_a: GO:2000696 {is_inferred="true"} ! regulation of epithelial cell differentiation involved in kidney development
 
 [Term]
 id: GO:0003340 ! negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
 is_a: GO:0003339 {is_inferred="true"} ! regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
-is_a: GO:0010771 {is_inferred="true"} ! negative regulation of cell morphogenesis involved in differentiation
-is_a: GO:0030857 {is_inferred="true"} ! negative regulation of epithelial cell differentiation
 is_a: GO:0072217 {is_inferred="true"} ! negative regulation of metanephros development
 is_a: GO:1905331 {is_inferred="true"} ! negative regulation of morphogenesis of an epithelium
+is_a: GO:2000697 {is_inferred="true"} ! negative regulation of epithelial cell differentiation involved in kidney development
 
 [Term]
 id: GO:0003348 ! cardiac endothelial cell differentiation
@@ -12863,19 +12863,19 @@
 
 [Term]
 id: GO:0010717 ! regulation of epithelial to mesenchymal transition
-is_a: GO:0010769 {is_inferred="true"} ! regulation of cell morphogenesis involved in differentiation
+is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
 is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
 
 [Term]
 id: GO:0010718 ! positive regulation of epithelial to mesenchymal transition
 is_a: GO:0010717 {is_inferred="true"} ! regulation of epithelial to mesenchymal transition
-is_a: GO:0010770 {is_inferred="true"} ! positive regulation of cell morphogenesis involved in differentiation
+is_a: GO:0010720 {is_inferred="true"} ! positive regulation of cell development
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 
 [Term]
 id: GO:0010719 ! negative regulation of epithelial to mesenchymal transition
 is_a: GO:0010717 {is_inferred="true"} ! regulation of epithelial to mesenchymal transition
-is_a: GO:0010771 {is_inferred="true"} ! negative regulation of cell morphogenesis involved in differentiation
+is_a: GO:0010721 {is_inferred="true"} ! negative regulation of cell development
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 
 [Term]
@@ -50533,7 +50533,9 @@
 
 [Term]
 id: GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis
+is_a: GO:0035850 {is_inferred="true"} ! epithelial cell differentiation involved in kidney development
 is_a: GO:0060231 {is_inferred="true"} ! mesenchymal to epithelial transition
+is_a: GO:0061208 {is_inferred="true"} ! cell differentiation involved in mesonephros development
 
 [Term]
 id: GO:0061271 ! mesenchymal to epithelial transition involved in mesonephric renal vesicle formation
@@ -55453,6 +55455,7 @@
 
 [Term]
 id: GO:0072036 ! mesenchymal to epithelial transition involved in renal vesicle formation
+is_a: GO:0035850 {is_inferred="true"} ! epithelial cell differentiation involved in kidney development
 is_a: GO:0060231 {is_inferred="true"} ! mesenchymal to epithelial transition
 
 [Term]
@@ -55602,10 +55605,9 @@
 [Term]
 id: GO:0072108 ! positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
 is_a: GO:0003339 {is_inferred="true"} ! regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
-is_a: GO:0010770 {is_inferred="true"} ! positive regulation of cell morphogenesis involved in differentiation
-is_a: GO:0030858 {is_inferred="true"} ! positive regulation of epithelial cell differentiation
 is_a: GO:0072216 {is_inferred="true"} ! positive regulation of metanephros development
 is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
+is_a: GO:2000698 {is_inferred="true"} ! positive regulation of epithelial cell differentiation involved in kidney development
 
 [Term]
 id: GO:0072111 ! cell proliferation involved in kidney development
@@ -59019,6 +59021,7 @@
 [Term]
 id: GO:0090299 ! regulation of neural crest formation
 is_a: GO:0010717 {is_inferred="true"} ! regulation of epithelial to mesenchymal transition
+is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
 is_a: GO:0045995 {is_inferred="true"} ! regulation of embryonic development
 
 [Term]
@@ -91030,24 +91033,21 @@
 
 [Term]
 id: GO:2000084 ! regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis
-is_a: GO:0010769 {is_inferred="true"} ! regulation of cell morphogenesis involved in differentiation
-is_a: GO:0030856 {is_inferred="true"} ! regulation of epithelial cell differentiation
 is_a: GO:0061217 {is_inferred="true"} ! regulation of mesonephros development
 is_a: GO:2000027 {is_inferred="true"} ! regulation of organ morphogenesis
+is_a: GO:2000696 {is_inferred="true"} ! regulation of epithelial cell differentiation involved in kidney development
 
 [Term]
 id: GO:2000085 ! negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis
-is_a: GO:0010771 {is_inferred="true"} ! negative regulation of cell morphogenesis involved in differentiation
-is_a: GO:0030857 {is_inferred="true"} ! negative regulation of epithelial cell differentiation
 is_a: GO:0061218 {is_inferred="true"} ! negative regulation of mesonephros development
 is_a: GO:2000084 {is_inferred="true"} ! regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis
+is_a: GO:2000697 {is_inferred="true"} ! negative regulation of epithelial cell differentiation involved in kidney development
 
 [Term]
 id: GO:2000086 ! positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis
-is_a: GO:0010770 {is_inferred="true"} ! positive regulation of cell morphogenesis involved in differentiation
-is_a: GO:0030858 {is_inferred="true"} ! positive regulation of epithelial cell differentiation
 is_a: GO:0061213 {is_inferred="true"} ! positive regulation of mesonephros development
 is_a: GO:2000084 {is_inferred="true"} ! regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis
+is_a: GO:2000698 {is_inferred="true"} ! positive regulation of epithelial cell differentiation involved in kidney development
 
 [Term]
 id: GO:2000087 ! regulation of mesonephric glomerulus development
------------------------------------------------------------------------
r35501 | tberardi | 2016-09-12 17:21:26 -0700 (Mon, 12 Sep 2016) | 1 line

GH12417 GO term specificity proposal 2 (gene product specific regulation via catabolism) - closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35501)
+++ go_inferences.obo	(working copy)
@@ -93650,22 +93650,6 @@
 is_a: GO:2000595 {is_inferred="true"} ! regulation of optic nerve formation
 
 [Term]
-id: GO:2000598 ! regulation of cyclin catabolic process
-is_a: GO:0000079 {is_inferred="true"} ! regulation of cyclin-dependent protein serine/threonine kinase activity
-is_a: GO:0032434 {is_inferred="true"} ! regulation of proteasomal ubiquitin-dependent protein catabolic process
-
-[Term]
-id: GO:2000599 ! negative regulation of cyclin catabolic process
-is_a: GO:0032435 {is_inferred="true"} ! negative regulation of proteasomal ubiquitin-dependent protein catabolic process
-is_a: GO:0045737 {is_inferred="true"} ! positive regulation of cyclin-dependent protein serine/threonine kinase activity
-is_a: GO:2000598 {is_inferred="true"} ! regulation of cyclin catabolic process
-
-[Term]
-id: GO:2000600 ! positive regulation of cyclin catabolic process
-is_a: GO:0032436 {is_inferred="true"} ! positive regulation of proteasomal ubiquitin-dependent protein catabolic process
-is_a: GO:2000598 {is_inferred="true"} ! regulation of cyclin catabolic process
-
-[Term]
 id: GO:2000601 ! positive regulation of Arp2/3 complex-mediated actin nucleation
 is_a: GO:0034315 {is_inferred="true"} ! regulation of Arp2/3 complex-mediated actin nucleation
 is_a: GO:0051127 {is_inferred="true"} ! positive regulation of actin nucleation
------------------------------------------------------------------------
r35496 | cjm | 2016-09-12 14:17:39 -0700 (Mon, 12 Sep 2016) | 1 line

Fixing #12654

changes in entailments

------------------------------------------------------------------------
r35496 | cjm | 2016-09-12 14:17:39 -0700 (Mon, 12 Sep 2016) | 1 line

Fixing #12654

changes in entailments

------------------------------------------------------------------------
r35451 | tberardi | 2016-09-09 16:28:15 -0700 (Fri, 09 Sep 2016) | 1 line

GH12619 GO structural problems with reproduction and sorocarp development etc. - closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35451)
+++ go_inferences.obo	(working copy)
@@ -20838,11 +20838,6 @@
 is_a: GO:1902583 {is_inferred="true"} ! multi-organism intracellular transport
 
 [Term]
-id: GO:0030587 ! sorocarp development
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
-
-[Term]
 id: GO:0030593 ! neutrophil chemotaxis
 is_a: GO:0071621 {is_inferred="true"} ! granulocyte chemotaxis
 is_a: GO:1990266 {is_inferred="true"} ! neutrophil migration
@@ -21822,28 +21817,15 @@
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 
 [Term]
-id: GO:0031152 ! aggregation involved in sorocarp development
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-
-[Term]
-id: GO:0031153 ! slug development involved in sorocarp development
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-
-[Term]
-id: GO:0031154 ! culmination involved in sorocarp development
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-
-[Term]
-id: GO:0031155 ! regulation of fruiting body development
+id: GO:0031155 ! regulation of reproductive fruiting body development
 is_a: GO:0075260 {is_inferred="true"} ! regulation of spore-bearing organ development
 
 [Term]
 id: GO:0031156 ! regulation of sorocarp development
 is_a: GO:0010646 {is_inferred="true"} ! regulation of cell communication
-is_a: GO:0031155 {is_inferred="true"} ! regulation of fruiting body development
 is_a: GO:0032107 {is_inferred="true"} ! regulation of response to nutrient levels
 is_a: GO:0080135 {is_inferred="true"} ! regulation of cellular response to stress
-is_a: GO:1903664 {is_inferred="true"} ! regulation of asexual reproduction
+is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
 
 [Term]
 id: GO:0031161 ! phosphatidylinositol catabolic process
@@ -22033,6 +22015,7 @@
 id: GO:0031285 ! regulation of sorocarp stalk cell differentiation
 is_a: GO:0031156 {is_inferred="true"} ! regulation of sorocarp development
 is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
+is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
 
 [Term]
 id: GO:0031286 ! negative regulation of sorocarp stalk cell differentiation
@@ -22039,7 +22022,6 @@
 is_a: GO:0010648 {is_inferred="true"} ! negative regulation of cell communication
 is_a: GO:0031285 {is_inferred="true"} ! regulation of sorocarp stalk cell differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
-is_a: GO:1903665 {is_inferred="true"} ! negative regulation of asexual reproduction
 
 [Term]
 id: GO:0031287 ! positive regulation of sorocarp stalk cell differentiation
@@ -22046,13 +22028,8 @@
 is_a: GO:0010647 {is_inferred="true"} ! positive regulation of cell communication
 is_a: GO:0031285 {is_inferred="true"} ! regulation of sorocarp stalk cell differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
-is_a: GO:1903666 {is_inferred="true"} ! positive regulation of asexual reproduction
 
 [Term]
-id: GO:0031288 ! sorocarp morphogenesis
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-
-[Term]
 id: GO:0031292 ! gene conversion at mating-type locus, DNA double-strand break processing
 is_a: GO:0000729 {is_inferred="true"} ! DNA double-strand break processing
 is_a: GO:0022414 {is_inferred="true"} ! reproductive process
@@ -57185,7 +57162,7 @@
 
 [Term]
 id: GO:0075268 ! regulation of aecium development
-is_a: GO:0031155 {is_inferred="true"} ! regulation of fruiting body development
+is_a: GO:0031155 {is_inferred="true"} ! regulation of reproductive fruiting body development
 
 [Term]
 id: GO:0075269 ! positive regulation of aecium development
@@ -69240,6 +69217,7 @@
 id: GO:1901261 ! regulation of sorocarp spore cell differentiation
 is_a: GO:0031156 {is_inferred="true"} ! regulation of sorocarp development
 is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
+is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
 
 [Term]
 id: GO:1901262 ! negative regulation of sorocarp spore cell differentiation
@@ -69246,9 +69224,9 @@
 is_a: GO:0010648 {is_inferred="true"} ! negative regulation of cell communication
 is_a: GO:0032108 {is_inferred="true"} ! negative regulation of response to nutrient levels
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
-is_a: GO:0075262 {is_inferred="true"} ! negative regulation of spore-bearing organ development
+is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1901261 {is_inferred="true"} ! regulation of sorocarp spore cell differentiation
-is_a: GO:1903665 {is_inferred="true"} ! negative regulation of asexual reproduction
+is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
 
 [Term]
 id: GO:1901263 ! positive regulation of sorocarp spore cell differentiation
@@ -69255,9 +69233,9 @@
 is_a: GO:0010647 {is_inferred="true"} ! positive regulation of cell communication
 is_a: GO:0032109 {is_inferred="true"} ! positive regulation of response to nutrient levels
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
-is_a: GO:0075261 {is_inferred="true"} ! positive regulation of spore-bearing organ development
+is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1901261 {is_inferred="true"} ! regulation of sorocarp spore cell differentiation
-is_a: GO:1903666 {is_inferred="true"} ! positive regulation of asexual reproduction
+is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
 
 [Term]
 id: GO:1901264 ! carbohydrate derivative transport
@@ -73258,7 +73236,7 @@
 
 [Term]
 id: GO:1902058 ! regulation of sporocarp development involved in sexual reproduction
-is_a: GO:0031155 {is_inferred="true"} ! regulation of fruiting body development
+is_a: GO:0031155 {is_inferred="true"} ! regulation of reproductive fruiting body development
 is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
 
 [Term]
------------------------------------------------------------------------
r35448 | dph | 2016-09-09 11:41:24 -0700 (Fri, 09 Sep 2016) | 2 lines

GH12639-closed.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35448)
+++ go_inferences.obo	(working copy)
@@ -4641,7 +4641,7 @@
 is_a: GO:0003380 {is_inferred="true"} ! establishment or maintenance of cytoskeleton polarity involved in gastrulation
 
 [Term]
-id: GO:0003375 ! regulation of dynamin polymerization involved in membrane fission
+id: GO:0003375 ! regulation of dynamin family protein polymerization involved in membrane fission
 is_a: GO:0032271 {is_inferred="true"} ! regulation of protein polymerization
 
 [Term]
------------------------------------------------------------------------
r35446 | dph | 2016-09-09 11:02:36 -0700 (Fri, 09 Sep 2016) | 2 lines

GH12526-closed

changes in entailments

------------------------------------------------------------------------
r35444 | dph | 2016-09-09 10:31:31 -0700 (Fri, 09 Sep 2016) | 2 lines

GH12635-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35444)
+++ go_inferences.obo	(working copy)
@@ -51220,6 +51220,11 @@
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 
 [Term]
+id: GO:0061792 ! secretory granule maturation
+is_a: GO:0021700 {is_inferred="true"} ! developmental maturation
+is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
@@ -90109,6 +90114,10 @@
 is_a: GO:0044444 {is_inferred="true"} ! cytoplasmic part
 
 [Term]
+id: GO:1990502 ! dense core granule maturation
+is_a: GO:0061792 {is_inferred="true"} ! secretory granule maturation
+
+[Term]
 id: GO:1990503 ! dendritic lamellar body
 is_a: GO:0044463 {is_inferred="true"} ! cell projection part
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
------------------------------------------------------------------------
r35442 | dph | 2016-09-09 10:20:38 -0700 (Fri, 09 Sep 2016) | 2 lines

GH12641-closed

changes in entailments

------------------------------------------------------------------------
r35440 | dph | 2016-09-09 08:50:21 -0700 (Fri, 09 Sep 2016) | 2 lines

Removed whitespace in synonyms of commited termgenie term, response to glycine.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35440)
+++ go_inferences.obo	(working copy)
@@ -89564,6 +89564,10 @@
 is_a: GO:0097724 {is_inferred="true"} ! sperm flagellum movement
 
 [Term]
+id: GO:1905420 ! vascular smooth muscle cell differentiation involved in phenotypic switching
+is_a: GO:0035886 {is_inferred="true"} ! vascular smooth muscle cell differentiation
+
+[Term]
 id: GO:1905421 ! regulation of plant organ morphogenesis
 is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
 is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
@@ -89606,6 +89610,15 @@
 is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
 
 [Term]
+id: GO:1905429 ! response to glycine
+is_a: GO:0043200 {is_inferred="true"} ! response to amino acid
+
+[Term]
+id: GO:1905430 ! cellular response to glycine
+is_a: GO:0071230 {is_inferred="true"} ! cellular response to amino acid stimulus
+is_a: GO:1905429 {is_inferred="true"} ! response to glycine
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35436 | davidos | 2016-09-09 08:22:05 -0700 (Fri, 09 Sep 2016) | 4 lines

Fixes final issue in:

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35436)
+++ go_inferences.obo	(working copy)
@@ -69137,7 +69137,7 @@
 is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 
 [Term]
-id: GO:1901242 ! doxorubicin transmembrane-transporting ATPase activity
+id: GO:1901242 ! ATPase-coupled doxorubicin transmembrane transporter activity
 is_a: GO:0042626 {is_inferred="true"} ! ATPase activity, coupled to transmembrane movement of substances
 is_a: GO:1901505 {is_inferred="true"} ! carbohydrate derivative transporter activity
 
@@ -70475,7 +70475,7 @@
 is_a: GO:0022857 {is_inferred="true"} ! transmembrane transporter activity
 
 [Term]
-id: GO:1901514 ! lipo-chitin oligosaccharide transmembrane-transporting ATPase activity
+id: GO:1901514 ! ATPase-coupled lipo-chitin oligosaccharide transmembrane transporter activity
 is_a: GO:0042626 {is_inferred="true"} ! ATPase activity, coupled to transmembrane movement of substances
 is_a: GO:1901513 {is_inferred="true"} ! lipo-chitin oligosaccharide transmembrane transporter activity
 
------------------------------------------------------------------------
r35420 | dph | 2016-09-08 13:04:41 -0700 (Thu, 08 Sep 2016) | 2 lines

GH12647-closed

changes in entailments

------------------------------------------------------------------------
r35418 | dph | 2016-09-08 12:40:19 -0700 (Thu, 08 Sep 2016) | 2 lines

GH12645-closed again

changes in entailments

------------------------------------------------------------------------
r35415 | dph | 2016-09-08 12:26:43 -0700 (Thu, 08 Sep 2016) | 2 lines

GH12648-closed

changes in entailments

------------------------------------------------------------------------
r35414 | dph | 2016-09-08 12:21:20 -0700 (Thu, 08 Sep 2016) | 2 lines

GH12649-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35414)
+++ go_inferences.obo	(working copy)
@@ -88064,15 +88064,15 @@
 is_a: GO:2000504 {is_inferred="true"} ! positive regulation of blood vessel remodeling
 
 [Term]
-id: GO:1905112 ! regulation of centromere clustering at the nuclear envelope
+id: GO:1905112 ! regulation of centromere clustering at the mitotic nuclear envelope
 is_a: GO:0007346 {is_inferred="true"} ! regulation of mitotic cell cycle
 is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
 
 [Term]
-id: GO:1905113 ! positive regulation of centromere clustering at the nuclear envelope
+id: GO:1905113 ! positive regulation of centromere clustering at the mitotic nuclear envelope
 is_a: GO:0045931 {is_inferred="true"} ! positive regulation of mitotic cell cycle
 is_a: GO:1903829 {is_inferred="true"} ! positive regulation of cellular protein localization
-is_a: GO:1905112 {is_inferred="true"} ! regulation of centromere clustering at the nuclear envelope
+is_a: GO:1905112 {is_inferred="true"} ! regulation of centromere clustering at the mitotic nuclear envelope
 
 [Term]
 id: GO:1905114 ! cell surface receptor signaling pathway involved in cell-cell signaling
------------------------------------------------------------------------
r35412 | termgenie | 2016-09-08 10:40:20 -0700 (Thu, 08 Sep 2016) | 7 lines

TermGenie commit for user: sp reviewed by dos

changes in entailments

------------------------------------------------------------------------
r35404 | dph | 2016-09-07 14:03:43 -0700 (Wed, 07 Sep 2016) | 2 lines

GH12436-closed.

changes in entailments

------------------------------------------------------------------------
r35402 | termgenie | 2016-09-07 11:59:51 -0700 (Wed, 07 Sep 2016) | 2 lines

TermGenie commit for user: tb reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35402)
+++ go_inferences.obo	(working copy)
@@ -89602,6 +89602,10 @@
 is_a: GO:0035556 {is_inferred="true"} ! intracellular signal transduction
 
 [Term]
+id: GO:1905428 ! regulation of plant organ formation
+is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
@@ -90728,6 +90732,7 @@
 [Term]
 id: GO:2000025 ! regulation of leaf formation
 is_a: GO:1901371 {is_inferred="true"} ! regulation of leaf morphogenesis
+is_a: GO:1905428 {is_inferred="true"} ! regulation of plant organ formation
 
 [Term]
 id: GO:2000026 ! regulation of multicellular organismal development
@@ -90762,6 +90767,7 @@
 id: GO:2000032 ! regulation of secondary shoot formation
 is_a: GO:0060688 {is_inferred="true"} ! regulation of morphogenesis of a branching structure
 is_a: GO:1900618 {is_inferred="true"} ! regulation of shoot system morphogenesis
+is_a: GO:1905428 {is_inferred="true"} ! regulation of plant organ formation
 
 [Term]
 id: GO:2000033 ! regulation of seed dormancy process
------------------------------------------------------------------------
r35399 | termgenie | 2016-09-07 11:18:06 -0700 (Wed, 07 Sep 2016) | 2 lines

TermGenie commit for user: dph reviewed by dph

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35399)
+++ go_inferences.obo	(working copy)
@@ -89598,6 +89598,10 @@
 is_a: GO:1905424 {is_inferred="true"} ! regulation of Wnt-mediated midbrain dopaminergic neuron differentiation
 
 [Term]
+id: GO:1905427 ! intracellular signal transduction involved in positive regulation of cell growth
+is_a: GO:0035556 {is_inferred="true"} ! intracellular signal transduction
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35395 | dph | 2016-09-07 08:23:38 -0700 (Wed, 07 Sep 2016) | 2 lines

Made cohesin loading an subtype of positive regulation of DNA binding.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35395)
+++ go_inferences.obo	(working copy)
@@ -55307,6 +55307,7 @@
 [Term]
 id: GO:0071922 ! regulation of cohesin loading
 is_a: GO:0007063 {is_inferred="true"} ! regulation of sister chromatid cohesion
+is_a: GO:0051101 {is_inferred="true"} ! regulation of DNA binding
 is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
 
 [Term]
------------------------------------------------------------------------
r35393 | dph | 2016-09-07 07:10:13 -0700 (Wed, 07 Sep 2016) | 2 lines

Removed MF is_a parent from cohesin loading.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35393)
+++ go_inferences.obo	(working copy)
@@ -89178,6 +89178,7 @@
 
 [Term]
 id: GO:1905338 ! negative regulation of cohesin unloading
+is_a: GO:0043388 {is_inferred="true"} ! positive regulation of DNA binding
 is_a: GO:0045876 {is_inferred="true"} ! positive regulation of sister chromatid cohesion
 is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
 is_a: GO:1905343 {is_inferred="true"} ! regulation of cohesin unloading
@@ -89204,6 +89205,7 @@
 [Term]
 id: GO:1905343 ! regulation of cohesin unloading
 is_a: GO:0007063 {is_inferred="true"} ! regulation of sister chromatid cohesion
+is_a: GO:0051101 {is_inferred="true"} ! regulation of DNA binding
 
 [Term]
 id: GO:1905344 ! prostaglandin catabolic process
------------------------------------------------------------------------
r35390 | termgenie | 2016-09-07 06:18:18 -0700 (Wed, 07 Sep 2016) | 4 lines

TermGenie commit for user: bf reviewed by dph

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35390)
+++ go_inferences.obo	(working copy)
@@ -89578,6 +89578,23 @@
 is_a: GO:1905421 {is_inferred="true"} ! regulation of plant organ morphogenesis
 
 [Term]
+id: GO:1905424 ! regulation of Wnt-mediated midbrain dopaminergic neuron differentiation
+is_a: GO:0030111 {is_inferred="true"} ! regulation of Wnt signaling pathway
+is_a: GO:1904956 {is_inferred="true"} ! regulation of midbrain dopaminergic neuron differentiation
+
+[Term]
+id: GO:1905425 ! negative regulation of Wnt-mediated midbrain dopaminergic neuron differentiation
+is_a: GO:0030178 {is_inferred="true"} ! negative regulation of Wnt signaling pathway
+is_a: GO:1904957 {is_inferred="true"} ! negative regulation of midbrain dopaminergic neuron differentiation
+is_a: GO:1905424 {is_inferred="true"} ! regulation of Wnt-mediated midbrain dopaminergic neuron differentiation
+
+[Term]
+id: GO:1905426 ! positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation
+is_a: GO:0030177 {is_inferred="true"} ! positive regulation of Wnt signaling pathway
+is_a: GO:1904958 {is_inferred="true"} ! positive regulation of midbrain dopaminergic neuron differentiation
+is_a: GO:1905424 {is_inferred="true"} ! regulation of Wnt-mediated midbrain dopaminergic neuron differentiation
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35382 | tberardi | 2016-09-06 17:48:06 -0700 (Tue, 06 Sep 2016) | 6 lines

Closes

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35382)
+++ go_inferences.obo	(working copy)
@@ -57292,10 +57292,6 @@
 is_a: GO:0075298 {is_inferred="true"} ! regulation of zygospore formation
 
 [Term]
-id: GO:0075301 ! cell differentiation involved in spore germination
-is_a: GO:0030154 {is_inferred="true"} ! cell differentiation
-
-[Term]
 id: GO:0075302 ! regulation of basidiospore formation
 is_a: GO:0043940 {is_inferred="true"} ! regulation of sexual sporulation resulting in formation of a cellular spore
 
------------------------------------------------------------------------
r35380 | termgenie | 2016-09-06 16:24:25 -0700 (Tue, 06 Sep 2016) | 4 lines

TermGenie commit for user: tb reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35380)
+++ go_inferences.obo	(working copy)
@@ -11339,15 +11339,15 @@
 id: GO:0010059 ! positive regulation of atrichoblast fate specification
 is_a: GO:0010058 {is_inferred="true"} ! regulation of atrichoblast fate specification
 is_a: GO:0042660 {is_inferred="true"} ! positive regulation of cell fate specification
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1903890 {is_inferred="true"} ! positive regulation of plant epidermal cell differentiation
+is_a: GO:1905423 {is_inferred="true"} ! positive regulation of plant organ morphogenesis
 
 [Term]
 id: GO:0010060 ! negative regulation of atrichoblast fate specification
 is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
 is_a: GO:0010058 {is_inferred="true"} ! regulation of atrichoblast fate specification
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1903889 {is_inferred="true"} ! negative regulation of plant epidermal cell differentiation
+is_a: GO:1905422 {is_inferred="true"} ! negative regulation of plant organ morphogenesis
 
 [Term]
 id: GO:0010061 ! regulation of trichoblast fate specification
@@ -11359,15 +11359,15 @@
 id: GO:0010062 ! negative regulation of trichoblast fate specification
 is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
 is_a: GO:0010061 {is_inferred="true"} ! regulation of trichoblast fate specification
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1903889 {is_inferred="true"} ! negative regulation of plant epidermal cell differentiation
+is_a: GO:1905422 {is_inferred="true"} ! negative regulation of plant organ morphogenesis
 
 [Term]
 id: GO:0010063 ! positive regulation of trichoblast fate specification
 is_a: GO:0010061 {is_inferred="true"} ! regulation of trichoblast fate specification
 is_a: GO:0042660 {is_inferred="true"} ! positive regulation of cell fate specification
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1903890 {is_inferred="true"} ! positive regulation of plant epidermal cell differentiation
+is_a: GO:1905423 {is_inferred="true"} ! positive regulation of plant organ morphogenesis
 
 [Term]
 id: GO:0010069 ! zygote asymmetric cytokinesis in embryo sac
@@ -58030,7 +58030,7 @@
 
 [Term]
 id: GO:0090015 ! positive regulation of leaflet formation by auxin mediated signaling pathway
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
+is_a: GO:1905423 {is_inferred="true"} ! positive regulation of plant organ morphogenesis
 
 [Term]
 id: GO:0090016 ! regulation of leaflet formation
@@ -69779,6 +69779,7 @@
 [Term]
 id: GO:1901371 ! regulation of leaf morphogenesis
 is_a: GO:1900618 {is_inferred="true"} ! regulation of shoot system morphogenesis
+is_a: GO:1905421 {is_inferred="true"} ! regulation of plant organ morphogenesis
 is_a: GO:2000024 {is_inferred="true"} ! regulation of leaf development
 
 [Term]
@@ -77237,19 +77238,19 @@
 id: GO:1902891 ! negative regulation of root hair elongation
 is_a: GO:0030308 {is_inferred="true"} ! negative regulation of cell growth
 is_a: GO:0048640 {is_inferred="true"} ! negative regulation of developmental growth
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1902890 {is_inferred="true"} ! regulation of root hair elongation
 is_a: GO:1903430 {is_inferred="true"} ! negative regulation of cell maturation
 is_a: GO:1903889 {is_inferred="true"} ! negative regulation of plant epidermal cell differentiation
+is_a: GO:1905422 {is_inferred="true"} ! negative regulation of plant organ morphogenesis
 
 [Term]
 id: GO:1902892 ! positive regulation of root hair elongation
 is_a: GO:0030307 {is_inferred="true"} ! positive regulation of cell growth
 is_a: GO:0048639 {is_inferred="true"} ! positive regulation of developmental growth
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1902890 {is_inferred="true"} ! regulation of root hair elongation
 is_a: GO:1903431 {is_inferred="true"} ! positive regulation of cell maturation
 is_a: GO:1903890 {is_inferred="true"} ! positive regulation of plant epidermal cell differentiation
+is_a: GO:1905423 {is_inferred="true"} ! positive regulation of plant organ morphogenesis
 
 [Term]
 id: GO:1902893 ! regulation of pri-miRNA transcription from RNA polymerase II promoter
@@ -89564,6 +89565,23 @@
 is_a: GO:0097724 {is_inferred="true"} ! sperm flagellum movement
 
 [Term]
+id: GO:1905421 ! regulation of plant organ morphogenesis
+is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
+is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
+
+[Term]
+id: GO:1905422 ! negative regulation of plant organ morphogenesis
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
+is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
+is_a: GO:1905421 {is_inferred="true"} ! regulation of plant organ morphogenesis
+
+[Term]
+id: GO:1905423 ! positive regulation of plant organ morphogenesis
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
+is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
+is_a: GO:1905421 {is_inferred="true"} ! regulation of plant organ morphogenesis
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
@@ -90896,7 +90914,7 @@
 
 [Term]
 id: GO:2000067 ! regulation of root morphogenesis
-is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
+is_a: GO:1905421 {is_inferred="true"} ! regulation of plant organ morphogenesis
 is_a: GO:2000280 {is_inferred="true"} ! regulation of root development
 
 [Term]
------------------------------------------------------------------------
r35376 | dph | 2016-09-06 11:35:22 -0700 (Tue, 06 Sep 2016) | 2 lines

GH12624-closed

changes in entailments

------------------------------------------------------------------------
r35374 | dph | 2016-09-06 11:24:33 -0700 (Tue, 06 Sep 2016) | 2 lines

GH12628-closed

changes in entailments

------------------------------------------------------------------------
r35372 | dph | 2016-09-06 10:43:20 -0700 (Tue, 06 Sep 2016) | 2 lines

Added vesicle fusion with vesicle.

changes in entailments

------------------------------------------------------------------------
r35370 | paola | 2016-09-06 05:55:23 -0700 (Tue, 06 Sep 2016) | 2 lines

GH smn protein complex #12595 - closed - added link ‘SMN-Sm protein complex’ has_part ‘SMN complex’

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35370)
+++ go_inferences.obo	(working copy)
@@ -2503,6 +2503,7 @@
 
 [Term]
 id: GO:0002548 ! monocyte chemotaxis
+is_a: GO:0071674 {is_inferred="true"} ! mononuclear cell migration
 is_a: GO:0097529 {is_inferred="true"} ! myeloid leukocyte migration
 
 [Term]
@@ -14004,6 +14005,26 @@
 is_a: GO:0048468 {is_inferred="true"} ! cell development
 
 [Term]
+id: GO:0014032 ! neural crest cell development
+is_a: GO:0048864 {is_inferred="true"} ! stem cell development
+
+[Term]
+id: GO:0014033 ! neural crest cell differentiation
+is_a: GO:0048863 {is_inferred="true"} ! stem cell differentiation
+
+[Term]
+id: GO:0014034 ! neural crest cell fate commitment
+is_a: GO:0048865 {is_inferred="true"} ! stem cell fate commitment
+
+[Term]
+id: GO:0014035 ! neural crest cell fate determination
+is_a: GO:0048867 {is_inferred="true"} ! stem cell fate determination
+
+[Term]
+id: GO:0014036 ! neural crest cell fate specification
+is_a: GO:0048866 {is_inferred="true"} ! stem cell fate specification
+
+[Term]
 id: GO:0014038 ! regulation of Schwann cell differentiation
 is_a: GO:0045685 {is_inferred="true"} ! regulation of glial cell differentiation
 
@@ -20424,6 +20445,10 @@
 is_a: GO:0048646 {is_inferred="true"} ! anatomical structure formation involved in morphogenesis
 
 [Term]
+id: GO:0030224 ! monocyte differentiation
+is_a: GO:1903131 {is_inferred="true"} ! mononuclear cell differentiation
+
+[Term]
 id: GO:0030234 ! enzyme regulator activity
 is_a: GO:0098772 {is_inferred="true"} ! molecular function regulator
 
@@ -29961,6 +29986,7 @@
 
 [Term]
 id: GO:0035696 ! monocyte extravasation
+is_a: GO:0071674 {is_inferred="true"} ! mononuclear cell migration
 is_a: GO:0097529 {is_inferred="true"} ! myeloid leukocyte migration
 
 [Term]
@@ -29973,6 +29999,7 @@
 
 [Term]
 id: GO:0035703 ! monocyte migration into blood stream
+is_a: GO:0071674 {is_inferred="true"} ! mononuclear cell migration
 is_a: GO:0097529 {is_inferred="true"} ! myeloid leukocyte migration
 
 [Term]
@@ -58042,15 +58069,18 @@
 [Term]
 id: GO:0090025 ! regulation of monocyte chemotaxis
 is_a: GO:0002688 {is_inferred="true"} ! regulation of leukocyte chemotaxis
+is_a: GO:0071675 {is_inferred="true"} ! regulation of mononuclear cell migration
 
 [Term]
 id: GO:0090026 ! positive regulation of monocyte chemotaxis
 is_a: GO:0002690 {is_inferred="true"} ! positive regulation of leukocyte chemotaxis
+is_a: GO:0071677 {is_inferred="true"} ! positive regulation of mononuclear cell migration
 is_a: GO:0090025 {is_inferred="true"} ! regulation of monocyte chemotaxis
 
 [Term]
 id: GO:0090027 ! negative regulation of monocyte chemotaxis
 is_a: GO:0002689 {is_inferred="true"} ! negative regulation of leukocyte chemotaxis
+is_a: GO:0071676 {is_inferred="true"} ! negative regulation of mononuclear cell migration
 is_a: GO:0090025 {is_inferred="true"} ! regulation of monocyte chemotaxis
 
 [Term]
@@ -88904,20 +88934,20 @@
 
 [Term]
 id: GO:1905292 ! regulation of neural crest cell differentiation
-is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
 is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
+is_a: GO:2000736 {is_inferred="true"} ! regulation of stem cell differentiation
 
 [Term]
 id: GO:1905293 ! negative regulation of neural crest cell differentiation
-is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1905292 {is_inferred="true"} ! regulation of neural crest cell differentiation
+is_a: GO:2000737 {is_inferred="true"} ! negative regulation of stem cell differentiation
 
 [Term]
 id: GO:1905294 ! positive regulation of neural crest cell differentiation
-is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1905292 {is_inferred="true"} ! regulation of neural crest cell differentiation
+is_a: GO:2000738 {is_inferred="true"} ! positive regulation of stem cell differentiation
 
 [Term]
 id: GO:1905295 ! regulation of neural crest cell fate specification
@@ -92793,15 +92823,18 @@
 [Term]
 id: GO:2000437 ! regulation of monocyte extravasation
 is_a: GO:0002691 {is_inferred="true"} ! regulation of cellular extravasation
+is_a: GO:0071675 {is_inferred="true"} ! regulation of mononuclear cell migration
 
 [Term]
 id: GO:2000438 ! negative regulation of monocyte extravasation
 is_a: GO:0002692 {is_inferred="true"} ! negative regulation of cellular extravasation
+is_a: GO:0071676 {is_inferred="true"} ! negative regulation of mononuclear cell migration
 is_a: GO:2000437 {is_inferred="true"} ! regulation of monocyte extravasation
 
 [Term]
 id: GO:2000439 ! positive regulation of monocyte extravasation
 is_a: GO:0002693 {is_inferred="true"} ! positive regulation of cellular extravasation
+is_a: GO:0071677 {is_inferred="true"} ! positive regulation of mononuclear cell migration
 is_a: GO:2000437 {is_inferred="true"} ! regulation of monocyte extravasation
 
 [Term]
------------------------------------------------------------------------
r35323 | tberardi | 2016-09-02 17:08:44 -0700 (Fri, 02 Sep 2016) | 17 lines

Fixed Jenkins detected errors.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35323)
+++ go_inferences.obo	(working copy)
@@ -10269,6 +10269,10 @@
 is_a: GO:1990204 {is_inferred="true"} ! oxidoreductase complex
 
 [Term]
+id: GO:0009336 ! sulfate adenylyltransferase complex (ATP)
+is_a: GO:1902503 {is_inferred="true"} ! adenylyltransferase complex
+
+[Term]
 id: GO:0009338 ! exodeoxyribonuclease V complex
 is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
 
@@ -35996,10 +36000,6 @@
 is_a: GO:0098927 {is_inferred="true"} ! vesicle-mediated transport between endosomal compartments
 
 [Term]
-id: GO:0045025 ! mitochondrial degradosome
-is_a: GO:0098798 {is_inferred="true"} ! mitochondrial protein complex
-
-[Term]
 id: GO:0045033 ! peroxisome inheritance
 is_a: GO:0048308 {is_inferred="true"} ! organelle inheritance
 
@@ -61940,6 +61940,7 @@
 [Term]
 id: GO:0099513 ! polymeric cytoskeletal fiber
 is_a: GO:0044430 {is_inferred="true"} ! cytoskeletal part
+is_a: GO:0099512 {is_inferred="true"} ! supramolecular fiber
 
 [Term]
 id: GO:0099514 ! synaptic vesicle cytoskeletal transport
@@ -89220,7 +89221,7 @@
 
 [Term]
 id: GO:1905354 ! exoribonuclease complex
-is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
+is_a: GO:0032991 {is_inferred="true"} ! macromolecular complex
 
 [Term]
 id: GO:1905355 ! spine apparatus assembly
@@ -89500,6 +89501,20 @@
 is_a: GO:1905405 {is_inferred="true"} ! regulation of mitotic cohesin loading
 
 [Term]
+id: GO:1905413 ! regulation of dense core granule exocytosis
+is_a: GO:0017158 {is_inferred="true"} ! regulation of calcium ion-dependent exocytosis
+
+[Term]
+id: GO:1905414 ! negative regulation of dense core granule exocytosis
+is_a: GO:0045955 {is_inferred="true"} ! negative regulation of calcium ion-dependent exocytosis
+is_a: GO:1905413 {is_inferred="true"} ! regulation of dense core granule exocytosis
+
+[Term]
+id: GO:1905415 ! positive regulation of dense core granule exocytosis
+is_a: GO:0045956 {is_inferred="true"} ! positive regulation of calcium ion-dependent exocytosis
+is_a: GO:1905413 {is_inferred="true"} ! regulation of dense core granule exocytosis
+
+[Term]
 id: GO:1905416 ! regulation of amoeboid sperm motility
 is_a: GO:2000145 {is_inferred="true"} ! regulation of cell motility
 
@@ -89514,6 +89529,11 @@
 is_a: GO:2000147 {is_inferred="true"} ! positive regulation of cell motility
 
 [Term]
+id: GO:1905419 ! sperm flagellum movement involved in flagellated sperm motility
+is_a: GO:0060294 {is_inferred="true"} ! cilium movement involved in cell motility
+is_a: GO:0097724 {is_inferred="true"} ! sperm flagellum movement
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
@@ -89665,6 +89685,7 @@
 [Term]
 id: GO:1990133 ! molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex
 is_a: GO:0044445 {is_inferred="true"} ! cytosolic part
+is_a: GO:1902503 {is_inferred="true"} ! adenylyltransferase complex
 
 [Term]
 id: GO:1990139 ! protein localization to nuclear periphery
@@ -89790,6 +89811,7 @@
 [Term]
 id: GO:1990235 ! diamine N-acetyltransferase complex
 is_a: GO:0044445 {is_inferred="true"} ! cytosolic part
+is_a: GO:1902493 {is_inferred="true"} ! acetyltransferase complex
 
 [Term]
 id: GO:1990236 ! proteasome core complex import into nucleus
------------------------------------------------------------------------
r35313 | mcourtot | 2016-09-02 07:37:31 -0700 (Fri, 02 Sep 2016) | 1 line

added related synonym chromatin modification to fix broken build

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35313)
+++ go_inferences.obo	(working copy)
@@ -13333,6 +13333,7 @@
 [Term]
 id: GO:0010847 ! regulation of chromatin assembly
 is_a: GO:0001672 {is_inferred="true"} ! regulation of chromatin assembly or disassembly
+is_a: GO:0033044 {is_inferred="true"} ! regulation of chromosome organization
 is_a: GO:0044087 {is_inferred="true"} ! regulation of cellular component biogenesis
 
 [Term]
@@ -22450,6 +22451,7 @@
 id: GO:0031452 ! negative regulation of heterochromatin assembly
 is_a: GO:0031445 {is_inferred="true"} ! regulation of heterochromatin assembly
 is_a: GO:0045798 {is_inferred="true"} ! negative regulation of chromatin assembly or disassembly
+is_a: GO:2001251 {is_inferred="true"} ! negative regulation of chromosome organization
 
 [Term]
 id: GO:0031453 ! positive regulation of heterochromatin assembly
@@ -22456,6 +22458,7 @@
 is_a: GO:0031445 {is_inferred="true"} ! regulation of heterochromatin assembly
 is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
 is_a: GO:0045799 {is_inferred="true"} ! positive regulation of chromatin assembly or disassembly
+is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
 
 [Term]
 id: GO:0031455 ! glycine betaine metabolic process
@@ -74315,7 +74318,7 @@
 
 [Term]
 id: GO:1902275 ! regulation of chromatin organization
-is_a: GO:0033044 {is_inferred="true"} ! regulation of chromosome organization
+is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 
 [Term]
 id: GO:1902276 ! regulation of pancreatic amylase secretion
@@ -78231,6 +78234,7 @@
 is_a: GO:0045798 {is_inferred="true"} ! negative regulation of chromatin assembly or disassembly
 is_a: GO:1900050 {is_inferred="true"} ! negative regulation of histone exchange
 is_a: GO:1903097 {is_inferred="true"} ! regulation of CENP-A containing nucleosome assembly
+is_a: GO:2001251 {is_inferred="true"} ! negative regulation of chromosome organization
 
 [Term]
 id: GO:1903099 ! positive regulation of CENP-A containing nucleosome assembly
@@ -78238,6 +78242,7 @@
 is_a: GO:0045799 {is_inferred="true"} ! positive regulation of chromatin assembly or disassembly
 is_a: GO:1900051 {is_inferred="true"} ! positive regulation of histone exchange
 is_a: GO:1903097 {is_inferred="true"} ! regulation of CENP-A containing nucleosome assembly
+is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
 
 [Term]
 id: GO:1903100 ! 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process
@@ -88771,13 +88776,13 @@
 
 [Term]
 id: GO:1905268 ! negative regulation of chromatin organization
+is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:1902275 {is_inferred="true"} ! regulation of chromatin organization
-is_a: GO:2001251 {is_inferred="true"} ! negative regulation of chromosome organization
 
 [Term]
 id: GO:1905269 ! positive regulation of chromatin organization
+is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 is_a: GO:1902275 {is_inferred="true"} ! regulation of chromatin organization
-is_a: GO:2001252 {is_inferred="true"} ! positive regulation of chromosome organization
 
 [Term]
 id: GO:1905270 ! Meynert cell differentiation
------------------------------------------------------------------------
r35294 | paola | 2016-09-01 06:02:42 -0700 (Thu, 01 Sep 2016) | 3 lines

GH placement of "sperm motility" #10905 - work in progress - see ticket for details

changes in entailments

------------------------------------------------------------------------
r35292 | termgenie | 2016-09-01 04:33:55 -0700 (Thu, 01 Sep 2016) | 4 lines

TermGenie commit for user: pr reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35292)
+++ go_inferences.obo	(working copy)
@@ -89495,6 +89495,20 @@
 is_a: GO:1905405 {is_inferred="true"} ! regulation of mitotic cohesin loading
 
 [Term]
+id: GO:1905416 ! regulation of amoeboid sperm motility
+is_a: GO:2000145 {is_inferred="true"} ! regulation of cell motility
+
+[Term]
+id: GO:1905417 ! negative regulation of amoeboid sperm motility
+is_a: GO:1905416 {is_inferred="true"} ! regulation of amoeboid sperm motility
+is_a: GO:2000146 {is_inferred="true"} ! negative regulation of cell motility
+
+[Term]
+id: GO:1905418 ! positive regulation of amoeboid sperm motility
+is_a: GO:1905416 {is_inferred="true"} ! regulation of amoeboid sperm motility
+is_a: GO:2000147 {is_inferred="true"} ! positive regulation of cell motility
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35290 | paola | 2016-09-01 04:06:12 -0700 (Thu, 01 Sep 2016) | 3 lines

GH placement of "sperm motility" #10905 - work in progress - see ticket for details

changes in entailments

------------------------------------------------------------------------
r35288 | paola | 2016-09-01 03:53:46 -0700 (Thu, 01 Sep 2016) | 3 lines

GH placement of "sperm motility" #10905 - work in progress - see ticket for details

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35288)
+++ go_inferences.obo	(working copy)
@@ -48691,9 +48691,9 @@
 is_a: GO:0050867 {is_inferred="true"} ! positive regulation of cell activation
 
 [Term]
-id: GO:0060474 ! positive regulation of sperm motility involved in capacitation
+id: GO:0060474 ! positive regulation of flagellated sperm motility involved in capacitation
 is_a: GO:0022414 {is_inferred="true"} ! reproductive process
-is_a: GO:1902093 {is_inferred="true"} ! positive regulation of sperm motility
+is_a: GO:1902093 {is_inferred="true"} ! positive regulation of flagellated sperm motility
 
 [Term]
 id: GO:0060475 ! positive regulation of actin filament polymerization involved in acrosome reaction
@@ -69473,12 +69473,12 @@
 is_a: GO:1902523 {is_inferred="true"} ! positive regulation of protein K63-linked ubiquitination
 
 [Term]
-id: GO:1901317 ! regulation of sperm motility
+id: GO:1901317 ! regulation of flagellated sperm motility
 is_a: GO:2000145 {is_inferred="true"} ! regulation of cell motility
 
 [Term]
-id: GO:1901318 ! negative regulation of sperm motility
-is_a: GO:1901317 {is_inferred="true"} ! regulation of sperm motility
+id: GO:1901318 ! negative regulation of flagellated sperm motility
+is_a: GO:1901317 {is_inferred="true"} ! regulation of flagellated sperm motility
 is_a: GO:2000146 {is_inferred="true"} ! negative regulation of cell motility
 
 [Term]
@@ -73403,8 +73403,8 @@
 is_a: GO:1902090 {is_inferred="true"} ! regulation of fumagillin biosynthetic process
 
 [Term]
-id: GO:1902093 ! positive regulation of sperm motility
-is_a: GO:1901317 {is_inferred="true"} ! regulation of sperm motility
+id: GO:1902093 ! positive regulation of flagellated sperm motility
+is_a: GO:1901317 {is_inferred="true"} ! regulation of flagellated sperm motility
 is_a: GO:2000147 {is_inferred="true"} ! positive regulation of cell motility
 
 [Term]
------------------------------------------------------------------------
r35275 | paola | 2016-08-30 05:59:39 -0700 (Tue, 30 Aug 2016) | 2 lines

GH NTR: ciliary vesicle #12563 - work in progress - added ‘ciliary vesicle’

changes in entailments

------------------------------------------------------------------------
r35269 | foulger | 2016-08-30 02:34:25 -0700 (Tue, 30 Aug 2016) | 16 lines

Added in relationship, based on PMID:27385586:

changes in entailments

------------------------------------------------------------------------
r35264 | tberardi | 2016-08-29 15:17:34 -0700 (Mon, 29 Aug 2016) | 1 line

GH12578 spore-bearing organs should not be classified as animal organs - incremental progress in separating animal and plant development

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35264)
+++ go_inferences.obo	(working copy)
@@ -11404,8 +11404,11 @@
 is_a: GO:0048831 {is_inferred="true"} ! regulation of shoot system development
 
 [Term]
+id: GO:0010092 ! specification of animal organ identity
+is_a: GO:0003002 {is_inferred="true"} ! regionalization
+
+[Term]
 id: GO:0010093 ! specification of floral organ identity
-is_a: GO:0003002 {is_inferred="true"} ! regionalization
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
@@ -59650,6 +59653,10 @@
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
+id: GO:0090701 ! specification of plant organ identity
+is_a: GO:0003002 {is_inferred="true"} ! regionalization
+
+[Term]
 id: GO:0093001 ! glycolysis from storage polysaccharide through glucose-1-phosphate
 is_a: GO:0000272 {is_inferred="true"} ! polysaccharide catabolic process
 is_a: GO:0061622 {is_inferred="true"} ! glycolytic process through glucose-1-phosphate
------------------------------------------------------------------------
r35262 | tberardi | 2016-08-29 14:27:37 -0700 (Mon, 29 Aug 2016) | 1 line

GH12616 correction of merotelic kinetochore attachment, meiosis I - closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35262)
+++ go_inferences.obo	(working copy)
@@ -59646,6 +59646,10 @@
 is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
+id: GO:0090699 ! correction of merotelic kinetochore attachment, meiosis I
+is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
+
+[Term]
 id: GO:0093001 ! glycolysis from storage polysaccharide through glucose-1-phosphate
 is_a: GO:0000272 {is_inferred="true"} ! polysaccharide catabolic process
 is_a: GO:0061622 {is_inferred="true"} ! glycolytic process through glucose-1-phosphate
@@ -60913,7 +60917,7 @@
 
 [Term]
 id: GO:0098783 ! correction of merotelic kinetochore attachment, mitotic
-is_a: GO:0022402 {is_inferred="true"} ! cell cycle process
+is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
 id: GO:0098784 ! biofilm matrix organization
------------------------------------------------------------------------
r35258 | termgenie | 2016-08-29 09:06:29 -0700 (Mon, 29 Aug 2016) | 2 lines

TermGenie commit for user: vw reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35258)
+++ go_inferences.obo	(working copy)
@@ -89478,6 +89478,12 @@
 is_a: GO:1905410 {is_inferred="true"} ! regulation of mitotic cohesin unloading
 
 [Term]
+id: GO:1905412 ! negative regulation of mitotic cohesin loading
+is_a: GO:0033048 {is_inferred="true"} ! negative regulation of mitotic sister chromatid segregation
+is_a: GO:0071923 {is_inferred="true"} ! negative regulation of cohesin loading
+is_a: GO:1905405 {is_inferred="true"} ! regulation of mitotic cohesin loading
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35220 | tberardi | 2016-08-26 15:32:01 -0700 (Fri, 26 Aug 2016) | 1 line

GH12617 sysonym for GO:1990501 exon-exon junction subcomplex mago-y14 - closed

changes in entailments

------------------------------------------------------------------------
r35184 | davidos | 2016-08-26 07:56:23 -0700 (Fri, 26 Aug 2016) | 1 line

added missing genus to GO:0006900

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35185)
+++ go_inferences.obo	(working copy)
@@ -255,8 +255,7 @@
 
 [Term]
 id: GO:0000101 ! sulfur amino acid transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
+is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
 is_a: GO:0072348 {is_inferred="true"} ! sulfur compound transport
 
 [Term]
@@ -288,6 +287,10 @@
 is_a: GO:0045892 {is_inferred="true"} ! negative regulation of transcription, DNA-templated
 
 [Term]
+id: GO:0000124 ! SAGA complex
+is_a: GO:1905368 {is_inferred="true"} ! peptidase complex
+
+[Term]
 id: GO:0000132 ! establishment of mitotic spindle orientation
 is_a: GO:0040001 {is_inferred="true"} ! establishment of mitotic spindle localization
 is_a: GO:0051294 {is_inferred="true"} ! establishment of spindle orientation
@@ -699,6 +702,10 @@
 is_a: GO:0022618 {is_inferred="true"} ! ribonucleoprotein complex assembly
 
 [Term]
+id: GO:0000502 ! proteasome complex
+is_a: GO:1905369 {is_inferred="true"} ! endopeptidase complex
+
+[Term]
 id: GO:0000706 ! meiotic DNA double-strand break processing
 is_a: GO:0000729 {is_inferred="true"} ! DNA double-strand break processing
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
@@ -1395,10 +1402,6 @@
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 
 [Term]
-id: GO:0001762 ! beta-alanine transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
-
-[Term]
 id: GO:0001765 ! membrane raft assembly
 is_a: GO:0071709 {is_inferred="true"} ! membrane assembly
 
@@ -1836,7 +1839,7 @@
 
 [Term]
 id: GO:0002018 ! renin-angiotensin regulation of aldosterone production
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:2000858 {is_inferred="true"} ! regulation of aldosterone secretion
 
 [Term]
 id: GO:0002028 ! regulation of sodium ion transport
@@ -1844,6 +1847,7 @@
 
 [Term]
 id: GO:0002036 ! regulation of L-glutamate transport
+is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
 is_a: GO:0051955 {is_inferred="true"} ! regulation of amino acid transport
 
 [Term]
@@ -1850,11 +1854,13 @@
 id: GO:0002037 ! negative regulation of L-glutamate transport
 is_a: GO:0002036 {is_inferred="true"} ! regulation of L-glutamate transport
 is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
+is_a: GO:1903792 {is_inferred="true"} ! negative regulation of anion transport
 
 [Term]
 id: GO:0002038 ! positive regulation of L-glutamate transport
 is_a: GO:0002036 {is_inferred="true"} ! regulation of L-glutamate transport
 is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
+is_a: GO:1903793 {is_inferred="true"} ! positive regulation of anion transport
 
 [Term]
 id: GO:0002044 ! blood vessel endothelial cell migration involved in intussusceptive angiogenesis
@@ -3046,7 +3052,6 @@
 [Term]
 id: GO:0002682 ! regulation of immune system process
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0002683 ! negative regulation of immune system process
@@ -4538,7 +4543,7 @@
 
 [Term]
 id: GO:0003333 ! amino acid transmembrane transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
+is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
 is_a: GO:1905039 {is_inferred="true"} ! carboxylic acid transmembrane transport
 
 [Term]
@@ -5175,6 +5180,10 @@
 is_a: GO:0044451 {is_inferred="true"} ! nucleoplasm part
 
 [Term]
+id: GO:0005671 ! Ada2/Gcn5/Ada3 transcription activator complex
+is_a: GO:1902562 {is_inferred="true"} ! H4 histone acetyltransferase complex
+
+[Term]
 id: GO:0005672 ! transcription factor TFIIA complex
 is_a: GO:0044451 {is_inferred="true"} ! nucleoplasm part
 
@@ -5229,6 +5238,7 @@
 [Term]
 id: GO:0005745 ! m-AAA complex
 is_a: GO:0098800 {is_inferred="true"} ! inner mitochondrial membrane protein complex
+is_a: GO:1905368 {is_inferred="true"} ! peptidase complex
 
 [Term]
 id: GO:0005746 ! mitochondrial respiratory chain
@@ -5317,8 +5327,9 @@
 
 [Term]
 id: GO:0005787 ! signal peptidase complex
+is_a: GO:0044432 {is_inferred="true"} ! endoplasmic reticulum part
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
-is_a: GO:1990234 {is_inferred="true"} ! transferase complex
+is_a: GO:1905368 {is_inferred="true"} ! peptidase complex
 
 [Term]
 id: GO:0005788 ! endoplasmic reticulum lumen
@@ -7818,12 +7829,10 @@
 [Term]
 id: GO:0006792 ! regulation of sulfur utilization
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0006795 ! regulation of phosphorus utilization
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0006796 ! phosphate-containing compound metabolic process
@@ -7855,7 +7864,6 @@
 [Term]
 id: GO:0006808 ! regulation of nitrogen utilization
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0006809 ! nitric oxide biosynthetic process
@@ -7989,10 +7997,18 @@
 
 [Term]
 id: GO:0006865 ! amino acid transport
-is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
 is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
+id: GO:0006867 ! asparagine transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+
+[Term]
+id: GO:0006868 ! glutamine transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+
+[Term]
 id: GO:0006869 ! lipid transport
 is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 
@@ -10319,6 +10335,10 @@
 is_a: GO:1990204 {is_inferred="true"} ! oxidoreductase complex
 
 [Term]
+id: GO:0009376 ! HslUV protease complex
+is_a: GO:1904949 {is_inferred="true"} ! ATPase complex
+
+[Term]
 id: GO:0009379 ! Holliday junction helicase complex
 is_a: GO:0033202 {is_inferred="true"} ! DNA helicase complex
 
@@ -12369,6 +12389,7 @@
 [Term]
 id: GO:0010585 ! glutamine secretion
 is_a: GO:0006868 {is_inferred="true"} ! glutamine transport
+is_a: GO:0046717 {is_inferred="true"} ! acid secretion
 
 [Term]
 id: GO:0010588 ! cotyledon vascular tissue pattern formation
@@ -13159,7 +13180,7 @@
 [Term]
 id: GO:0010806 ! negative regulation of lysine import
 is_a: GO:0010805 {is_inferred="true"} ! regulation of lysine import
-is_a: GO:0032891 {is_inferred="true"} ! negative regulation of organic acid transport
+is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
 
 [Term]
 id: GO:0010807 ! regulation of synaptic vesicle priming
@@ -13737,7 +13758,7 @@
 
 [Term]
 id: GO:0010958 ! regulation of amino acid import
-is_a: GO:0032890 {is_inferred="true"} ! regulation of organic acid transport
+is_a: GO:0051955 {is_inferred="true"} ! regulation of amino acid transport
 
 [Term]
 id: GO:0010959 ! regulation of metal ion transport
@@ -14037,20 +14058,20 @@
 
 [Term]
 id: GO:0014052 ! regulation of gamma-aminobutyric acid secretion
+is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
 is_a: GO:0051046 {is_inferred="true"} ! regulation of secretion
-is_a: GO:0051955 {is_inferred="true"} ! regulation of amino acid transport
 
 [Term]
 id: GO:0014053 ! negative regulation of gamma-aminobutyric acid secretion
 is_a: GO:0014052 {is_inferred="true"} ! regulation of gamma-aminobutyric acid secretion
 is_a: GO:0051048 {is_inferred="true"} ! negative regulation of secretion
-is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
+is_a: GO:1903792 {is_inferred="true"} ! negative regulation of anion transport
 
 [Term]
 id: GO:0014054 ! positive regulation of gamma-aminobutyric acid secretion
 is_a: GO:0014052 {is_inferred="true"} ! regulation of gamma-aminobutyric acid secretion
 is_a: GO:0051047 {is_inferred="true"} ! positive regulation of secretion
-is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
+is_a: GO:1903793 {is_inferred="true"} ! positive regulation of anion transport
 
 [Term]
 id: GO:0014056 ! regulation of acetylcholine secretion, neurotransmission
@@ -14368,6 +14389,7 @@
 
 [Term]
 id: GO:0014861 ! regulation of skeletal muscle contraction via regulation of action potential
+is_a: GO:0014819 {is_inferred="true"} ! regulation of skeletal muscle contraction
 is_a: GO:0098900 {is_inferred="true"} ! regulation of action potential
 
 [Term]
@@ -15730,13 +15752,11 @@
 
 [Term]
 id: GO:0015801 ! aromatic amino acid transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
+is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
 
 [Term]
 id: GO:0015803 ! branched-chain amino acid transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
+is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
 
 [Term]
 id: GO:0015805 ! S-adenosyl-L-methionine transport
@@ -15748,7 +15768,8 @@
 
 [Term]
 id: GO:0015807 ! L-amino acid transport
-is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
 id: GO:0015808 ! L-alanine transport
@@ -15756,6 +15777,10 @@
 is_a: GO:0032328 {is_inferred="true"} ! alanine transport
 
 [Term]
+id: GO:0015809 ! arginine transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+
+[Term]
 id: GO:0015810 ! aspartate transport
 is_a: GO:0015740 {is_inferred="true"} ! C4-dicarboxylate transport
 
@@ -15766,7 +15791,8 @@
 
 [Term]
 id: GO:0015812 ! gamma-aminobutyric acid transport
-is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
 id: GO:0015813 ! L-glutamate transport
@@ -15778,26 +15804,53 @@
 is_a: GO:0006835 {is_inferred="true"} ! dicarboxylic acid transport
 
 [Term]
+id: GO:0015816 ! glycine transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+
+[Term]
+id: GO:0015817 ! histidine transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+
+[Term]
 id: GO:0015818 ! isoleucine transport
 is_a: GO:0015803 {is_inferred="true"} ! branched-chain amino acid transport
 
 [Term]
+id: GO:0015819 ! lysine transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+
+[Term]
+id: GO:0015820 ! leucine transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+
+[Term]
 id: GO:0015821 ! methionine transport
-is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
 id: GO:0015822 ! ornithine transport
-is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
 id: GO:0015823 ! phenylalanine transport
-is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
+id: GO:0015824 ! proline transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+
+[Term]
 id: GO:0015825 ! L-serine transport
 is_a: GO:0015807 {is_inferred="true"} ! L-amino acid transport
 
 [Term]
+id: GO:0015826 ! threonine transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+
+[Term]
 id: GO:0015827 ! tryptophan transport
 is_a: GO:0015801 {is_inferred="true"} ! aromatic amino acid transport
 
@@ -15806,9 +15859,12 @@
 is_a: GO:0015801 {is_inferred="true"} ! aromatic amino acid transport
 
 [Term]
+id: GO:0015829 ! valine transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+
+[Term]
 id: GO:0015830 ! diaminopimelate transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
+is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
 
 [Term]
 id: GO:0015833 ! peptide transport
@@ -17712,7 +17768,6 @@
 [Term]
 id: GO:0019222 ! regulation of metabolic process
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0019229 ! regulation of vasoconstriction
@@ -19987,7 +20042,6 @@
 [Term]
 id: GO:0023051 ! regulation of signaling
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0023056 ! positive regulation of signaling
@@ -20191,7 +20245,6 @@
 [Term]
 id: GO:0030155 ! regulation of cell adhesion
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0030162 ! regulation of proteolysis
@@ -21626,6 +21679,10 @@
 is_a: GO:0031066 {is_inferred="true"} ! regulation of histone deacetylation at centromere
 
 [Term]
+id: GO:0031082 ! BLOC complex
+is_a: GO:0044445 {is_inferred="true"} ! cytosolic part
+
+[Term]
 id: GO:0031095 ! platelet dense tubular network membrane
 is_a: GO:0098588 {is_inferred="true"} ! bounding membrane of organelle
 
@@ -22131,7 +22188,6 @@
 [Term]
 id: GO:0031341 ! regulation of cell killing
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0031342 ! negative regulation of cell killing
@@ -23858,8 +23914,8 @@
 is_a: GO:0042046 {is_inferred="true"} ! W-molybdopterin cofactor metabolic process
 
 [Term]
-id: GO:0032329 ! serine transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
+id: GO:0032328 ! alanine transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
 
 [Term]
 id: GO:0032330 ! regulation of chondrocyte differentiation
@@ -25528,7 +25584,6 @@
 [Term]
 id: GO:0032879 ! regulation of localization
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0032880 ! regulation of protein localization
@@ -25862,8 +25917,7 @@
 
 [Term]
 id: GO:0032973 ! amino acid export
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
+is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
 
 [Term]
 id: GO:0032974 ! amino acid transmembrane export from vacuole
@@ -28599,23 +28653,13 @@
 id: GO:0034488 ! basic amino acid transmembrane export from vacuole
 is_a: GO:0015802 {is_inferred="true"} ! basic amino acid transport
 is_a: GO:0032974 {is_inferred="true"} ! amino acid transmembrane export from vacuole
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
 id: GO:0034489 ! neutral amino acid transmembrane export from vacuole
 is_a: GO:0015804 {is_inferred="true"} ! neutral amino acid transport
 is_a: GO:0032974 {is_inferred="true"} ! amino acid transmembrane export from vacuole
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
-id: GO:0034490 ! basic amino acid transmembrane import into vacuole
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
-
-[Term]
-id: GO:0034491 ! neutral amino acid transmembrane import into vacuole
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
-
-[Term]
 id: GO:0034496 ! multivesicular body membrane disassembly
 is_a: GO:0030397 {is_inferred="true"} ! membrane disassembly
 
@@ -28651,7 +28695,7 @@
 
 [Term]
 id: GO:0034589 ! hydroxyproline transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
+is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
 is_a: GO:0072337 {is_inferred="true"} ! modified amino acid transport
 
 [Term]
@@ -29221,6 +29265,10 @@
 is_a: GO:0048589 {is_inferred="true"} ! developmental growth
 
 [Term]
+id: GO:0035267 ! NuA4 histone acetyltransferase complex
+is_a: GO:0043189 {is_inferred="true"} ! H4/H2A histone acetyltransferase complex
+
+[Term]
 id: GO:0035273 ! phthalate binding
 is_a: GO:0031406 {is_inferred="true"} ! carboxylic acid binding
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
@@ -31179,12 +31227,10 @@
 [Term]
 id: GO:0040008 ! regulation of growth
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0040012 ! regulation of locomotion
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0040013 ! negative regulation of locomotion
@@ -32853,7 +32899,6 @@
 [Term]
 id: GO:0042752 ! regulation of circadian rhythm
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0042753 ! positive regulation of circadian rhythm
@@ -33361,7 +33406,8 @@
 
 [Term]
 id: GO:0042940 ! D-amino acid transport
-is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
 id: GO:0042941 ! D-alanine transport
@@ -33433,6 +33479,10 @@
 is_a: GO:0015159 {is_inferred="true"} ! polysaccharide transmembrane transporter activity
 
 [Term]
+id: GO:0042968 ! homoserine transport
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
+
+[Term]
 id: GO:0042969 ! lactone transport
 is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 
@@ -33656,8 +33706,7 @@
 
 [Term]
 id: GO:0043090 ! amino acid import
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
+is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
 
 [Term]
 id: GO:0043091 ! L-arginine import
@@ -34761,12 +34810,10 @@
 [Term]
 id: GO:0043609 ! regulation of carbon utilization
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0043610 ! regulation of carbohydrate utilization
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0043611 ! isoprene metabolic process
@@ -34984,7 +35031,6 @@
 [Term]
 id: GO:0043900 ! regulation of multi-organism process
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0043901 ! negative regulation of multi-organism process
@@ -35160,10 +35206,6 @@
 is_a: GO:0043269 {is_inferred="true"} ! regulation of ion transport
 
 [Term]
-id: GO:0044087 ! regulation of cellular component biogenesis
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
-
-[Term]
 id: GO:0044088 ! regulation of vacuole organization
 is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
 
@@ -35595,6 +35637,10 @@
 is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
 
 [Term]
+id: GO:0044545 ! NSL complex
+is_a: GO:1902562 {is_inferred="true"} ! H4 histone acetyltransferase complex
+
+[Term]
 id: GO:0044552 ! modulation of vasodilation in other organism
 is_a: GO:0044706 {is_inferred="true"} ! multi-multicellular organism process
 
@@ -38156,12 +38202,10 @@
 
 [Term]
 id: GO:0045759 ! negative regulation of action potential
-is_a: GO:0042391 {is_inferred="true"} ! regulation of membrane potential
 is_a: GO:0098900 {is_inferred="true"} ! regulation of action potential
 
 [Term]
 id: GO:0045760 ! positive regulation of action potential
-is_a: GO:0042391 {is_inferred="true"} ! regulation of membrane potential
 is_a: GO:0098900 {is_inferred="true"} ! regulation of action potential
 
 [Term]
@@ -42195,7 +42239,6 @@
 [Term]
 id: GO:0048070 ! regulation of developmental pigmentation
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0048071 ! sex-specific pigmentation
@@ -42901,12 +42944,10 @@
 [Term]
 id: GO:0048518 ! positive regulation of biological process
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0048519 ! negative regulation of biological process
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0048520 ! positive regulation of behavior
@@ -43035,7 +43076,6 @@
 [Term]
 id: GO:0048583 ! regulation of response to stimulus
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0048584 ! positive regulation of response to stimulus
@@ -44092,10 +44132,6 @@
 is_a: GO:0061687 {is_inferred="true"} ! detoxification of inorganic compound
 
 [Term]
-id: GO:0050789 ! regulation of biological process
-is_a: GO:0008150 {is_inferred="true"} ! biological_process
-
-[Term]
 id: GO:0050790 ! regulation of catalytic activity
 is_a: GO:0065009 {is_inferred="true"} ! regulation of molecular function
 
@@ -44107,17 +44143,14 @@
 [Term]
 id: GO:0050793 ! regulation of developmental process
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0050794 ! regulation of cellular process
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0050795 ! regulation of behavior
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0050796 ! regulation of insulin secretion
@@ -45262,7 +45295,6 @@
 [Term]
 id: GO:0051239 ! regulation of multicellular organismal process
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:0051240 ! positive regulation of multicellular organismal process
@@ -46874,8 +46906,8 @@
 
 [Term]
 id: GO:0051938 ! L-glutamate import
-is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
 is_a: GO:0043090 {is_inferred="true"} ! amino acid import
+is_a: GO:0046942 {is_inferred="true"} ! carboxylic acid transport
 
 [Term]
 id: GO:0051939 ! gamma-aminobutyric acid import
@@ -46894,15 +46926,15 @@
 
 [Term]
 id: GO:0051942 ! negative regulation of amino acid uptake involved in synaptic transmission
-is_a: GO:0032891 {is_inferred="true"} ! negative regulation of organic acid transport
 is_a: GO:0051581 {is_inferred="true"} ! negative regulation of neurotransmitter uptake
 is_a: GO:0051941 {is_inferred="true"} ! regulation of amino acid uptake involved in synaptic transmission
+is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
 
 [Term]
 id: GO:0051943 ! positive regulation of amino acid uptake involved in synaptic transmission
-is_a: GO:0032892 {is_inferred="true"} ! positive regulation of organic acid transport
 is_a: GO:0051582 {is_inferred="true"} ! positive regulation of neurotransmitter uptake
 is_a: GO:0051941 {is_inferred="true"} ! regulation of amino acid uptake involved in synaptic transmission
+is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
 
 [Term]
 id: GO:0051944 ! positive regulation of catecholamine uptake involved in synaptic transmission
@@ -46961,17 +46993,17 @@
 
 [Term]
 id: GO:0051955 ! regulation of amino acid transport
-is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
+is_a: GO:0032890 {is_inferred="true"} ! regulation of organic acid transport
 
 [Term]
 id: GO:0051956 ! negative regulation of amino acid transport
+is_a: GO:0032891 {is_inferred="true"} ! negative regulation of organic acid transport
 is_a: GO:0051955 {is_inferred="true"} ! regulation of amino acid transport
-is_a: GO:1903792 {is_inferred="true"} ! negative regulation of anion transport
 
 [Term]
 id: GO:0051957 ! positive regulation of amino acid transport
+is_a: GO:0032892 {is_inferred="true"} ! positive regulation of organic acid transport
 is_a: GO:0051955 {is_inferred="true"} ! regulation of amino acid transport
-is_a: GO:1903793 {is_inferred="true"} ! positive regulation of anion transport
 
 [Term]
 id: GO:0051958 ! methotrexate transport
@@ -48377,7 +48409,7 @@
 
 [Term]
 id: GO:0060358 ! negative regulation of leucine import
-is_a: GO:0032891 {is_inferred="true"} ! negative regulation of organic acid transport
+is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
 is_a: GO:0060357 {is_inferred="true"} ! regulation of leucine import
 
 [Term]
@@ -49121,7 +49153,8 @@
 
 [Term]
 id: GO:0060657 ! regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0048638 {is_inferred="true"} ! regulation of developmental growth
+is_a: GO:0060762 {is_inferred="true"} ! regulation of branching involved in mammary gland duct morphogenesis
 
 [Term]
 id: GO:0060660 ! epidermis morphogenesis involved in nipple formation
@@ -50933,6 +50966,7 @@
 [Term]
 id: GO:0061528 ! aspartate secretion
 is_a: GO:0015810 {is_inferred="true"} ! aspartate transport
+is_a: GO:0046717 {is_inferred="true"} ! acid secretion
 
 [Term]
 id: GO:0061531 ! primary amine secretion
@@ -50940,9 +50974,8 @@
 
 [Term]
 id: GO:0061536 ! glycine secretion
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
+is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
 is_a: GO:0046717 {is_inferred="true"} ! acid secretion
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
 id: GO:0061539 ! octopamine secretion
@@ -52091,6 +52124,10 @@
 is_a: GO:0009306 {is_inferred="true"} ! protein secretion
 
 [Term]
+id: GO:0070461 ! SAGA-type complex
+is_a: GO:0000123 {is_inferred="true"} ! histone acetyltransferase complex
+
+[Term]
 id: GO:0070464 ! alphav-beta3 integrin-collagen alpha3(VI) complex
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
@@ -52513,7 +52550,7 @@
 
 [Term]
 id: GO:0070676 ! intralumenal vesicle formation
-is_a: GO:0006900 {is_inferred="true"} ! membrane budding
+is_a: GO:0007032 {is_inferred="true"} ! endosome organization
 
 [Term]
 id: GO:0070689 ! L-threonine catabolic process to propionate
@@ -52642,6 +52679,10 @@
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
 [Term]
+id: GO:0070775 ! H3 histone acetyltransferase complex
+is_a: GO:0000123 {is_inferred="true"} ! histone acetyltransferase complex
+
+[Term]
 id: GO:0070777 ! D-aspartate transport
 is_a: GO:0015810 {is_inferred="true"} ! aspartate transport
 
@@ -52908,6 +52949,7 @@
 
 [Term]
 id: GO:0070881 ! regulation of proline transport
+is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
 is_a: GO:0051955 {is_inferred="true"} ! regulation of amino acid transport
 
 [Term]
@@ -55022,11 +55064,13 @@
 
 [Term]
 id: GO:0071809 ! regulation of fever generation by regulation of prostaglandin biosynthesis
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0031392 {is_inferred="true"} ! regulation of prostaglandin biosynthetic process
+is_a: GO:0031620 {is_inferred="true"} ! regulation of fever generation
 
 [Term]
 id: GO:0071810 ! regulation of fever generation by regulation of prostaglandin secretion
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0031620 {is_inferred="true"} ! regulation of fever generation
+is_a: GO:0032306 {is_inferred="true"} ! regulation of prostaglandin secretion
 
 [Term]
 id: GO:0071811 ! positive regulation of fever generation by positive regulation of prostaglandin biosynthesis
@@ -55202,6 +55246,7 @@
 [Term]
 id: GO:0071898 ! regulation of estrogen receptor binding
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:1900120 {is_inferred="true"} ! regulation of receptor binding
 
 [Term]
 id: GO:0071899 ! negative regulation of estrogen receptor binding
@@ -56227,6 +56272,10 @@
 is_a: GO:0072416 {is_inferred="true"} ! signal transduction involved in spindle checkpoint
 
 [Term]
+id: GO:0072487 ! MSL complex
+is_a: GO:1902562 {is_inferred="true"} ! H4 histone acetyltransferase complex
+
+[Term]
 id: GO:0072488 ! ammonium transmembrane transport
 is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 is_a: GO:0098655 {is_inferred="true"} ! cation transmembrane transport
@@ -57518,10 +57567,6 @@
 is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
 
 [Term]
-id: GO:0080143 ! regulation of amino acid export
-is_a: GO:0032890 {is_inferred="true"} ! regulation of organic acid transport
-
-[Term]
 id: GO:0080144 ! amino acid homeostasis
 is_a: GO:0048878 {is_inferred="true"} ! chemical homeostasis
 
@@ -57850,12 +57895,12 @@
 
 [Term]
 id: GO:0089703 ! L-aspartate transmembrane export from vacuole
-is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
+is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
 is_a: GO:0089712 {is_inferred="true"} ! L-aspartate transmembrane transport
 
 [Term]
 id: GO:0089704 ! L-glutamate transmembrane export from vacuole
-is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
+is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
 is_a: GO:0089711 {is_inferred="true"} ! L-glutamate transmembrane transport
 
 [Term]
@@ -57885,10 +57930,12 @@
 
 [Term]
 id: GO:0089711 ! L-glutamate transmembrane transport
+is_a: GO:0003333 {is_inferred="true"} ! amino acid transmembrane transport
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
 id: GO:0089712 ! L-aspartate transmembrane transport
+is_a: GO:0003333 {is_inferred="true"} ! amino acid transmembrane transport
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
@@ -59090,7 +59137,9 @@
 
 [Term]
 id: GO:0090326 ! positive regulation of locomotion involved in locomotory behavior
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0040017 {is_inferred="true"} ! positive regulation of locomotion
+is_a: GO:0048520 {is_inferred="true"} ! positive regulation of behavior
+is_a: GO:0090325 {is_inferred="true"} ! regulation of locomotion involved in locomotory behavior
 
 [Term]
 id: GO:0090327 ! negative regulation of locomotion involved in locomotory behavior
@@ -59396,7 +59445,7 @@
 [Term]
 id: GO:0090453 ! aspartate transmembrane import into vacuole
 is_a: GO:0015810 {is_inferred="true"} ! aspartate transport
-is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
+is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
@@ -60756,7 +60805,6 @@
 id: GO:0098718 ! serine import across plasma membrane
 is_a: GO:0061491 {is_inferred="true"} ! serine import into cell
 is_a: GO:0089718 {is_inferred="true"} ! amino acid import across plasma membrane
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
 id: GO:0098719 ! sodium ion import across plasma membrane
@@ -60865,8 +60913,7 @@
 
 [Term]
 id: GO:0098783 ! correction of merotelic kinetochore attachment, mitotic
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
+is_a: GO:0022402 {is_inferred="true"} ! cell cycle process
 
 [Term]
 id: GO:0098784 ! biofilm matrix organization
@@ -61139,14 +61186,11 @@
 
 [Term]
 id: GO:0098884 ! postsynaptic neurotransmitter receptor internalization
-is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
-is_a: GO:0099003 {is_inferred="true"} ! vesicle-mediated transport in synapse
+is_a: GO:0099590 {is_inferred="true"} ! neurotransmitter receptor internalization
 
 [Term]
 id: GO:0098887 ! neurotransmitter receptor transport, endosome to postsynaptic membrane
-is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
 is_a: GO:0098969 {is_inferred="true"} ! neurotransmitter receptor transport to postsynaptic membrane
-is_a: GO:0099003 {is_inferred="true"} ! vesicle-mediated transport in synapse
 is_a: GO:0099639 {is_inferred="true"} ! neurotransmitter receptor transport, endosome to plasma membrane
 
 [Term]
@@ -61210,46 +61254,59 @@
 is_a: GO:0044463 {is_inferred="true"} ! cell projection part
 
 [Term]
+id: GO:0098900 ! regulation of action potential
+is_a: GO:0042391 {is_inferred="true"} ! regulation of membrane potential
+
+[Term]
 id: GO:0098901 ! regulation of cardiac muscle cell action potential
 is_a: GO:0098900 {is_inferred="true"} ! regulation of action potential
 
 [Term]
 id: GO:0098902 ! regulation of membrane depolarization during action potential
+is_a: GO:0003254 {is_inferred="true"} ! regulation of membrane depolarization
 is_a: GO:0098900 {is_inferred="true"} ! regulation of action potential
 
 [Term]
 id: GO:0098903 ! regulation of membrane repolarization during action potential
+is_a: GO:0060306 {is_inferred="true"} ! regulation of membrane repolarization
 is_a: GO:0098900 {is_inferred="true"} ! regulation of action potential
 
 [Term]
 id: GO:0098904 ! regulation of AV node cell action potential
+is_a: GO:0010646 {is_inferred="true"} ! regulation of cell communication
 is_a: GO:0098901 {is_inferred="true"} ! regulation of cardiac muscle cell action potential
+is_a: GO:1903779 {is_inferred="true"} ! regulation of cardiac conduction
 
 [Term]
 id: GO:0098905 ! regulation of bundle of His cell action potential
+is_a: GO:0010646 {is_inferred="true"} ! regulation of cell communication
 is_a: GO:0098901 {is_inferred="true"} ! regulation of cardiac muscle cell action potential
+is_a: GO:1903779 {is_inferred="true"} ! regulation of cardiac conduction
 
 [Term]
 id: GO:0098906 ! regulation of Purkinje myocyte action potential
+is_a: GO:0010646 {is_inferred="true"} ! regulation of cell communication
 is_a: GO:0098901 {is_inferred="true"} ! regulation of cardiac muscle cell action potential
+is_a: GO:1903779 {is_inferred="true"} ! regulation of cardiac conduction
 
 [Term]
 id: GO:0098907 ! regulation of SA node cell action potential
+is_a: GO:0010646 {is_inferred="true"} ! regulation of cell communication
 is_a: GO:0098901 {is_inferred="true"} ! regulation of cardiac muscle cell action potential
+is_a: GO:1903779 {is_inferred="true"} ! regulation of cardiac conduction
 
 [Term]
 id: GO:0098908 ! regulation of neuronal action potential
+is_a: GO:0051969 {is_inferred="true"} ! regulation of transmission of nerve impulse
 is_a: GO:0098900 {is_inferred="true"} ! regulation of action potential
 
 [Term]
 id: GO:0098909 ! regulation of cardiac muscle cell action potential involved in regulation of contraction
-is_a: GO:0042391 {is_inferred="true"} ! regulation of membrane potential
 is_a: GO:0098901 {is_inferred="true"} ! regulation of cardiac muscle cell action potential
 
 [Term]
 id: GO:0098910 ! regulation of atrial cardiac muscle cell action potential
 is_a: GO:0010646 {is_inferred="true"} ! regulation of cell communication
-is_a: GO:0042391 {is_inferred="true"} ! regulation of membrane potential
 is_a: GO:0086004 {is_inferred="true"} ! regulation of cardiac muscle cell contraction
 is_a: GO:0098901 {is_inferred="true"} ! regulation of cardiac muscle cell action potential
 is_a: GO:1903779 {is_inferred="true"} ! regulation of cardiac conduction
@@ -61256,7 +61313,6 @@
 
 [Term]
 id: GO:0098911 ! regulation of ventricular cardiac muscle cell action potential
-is_a: GO:0042391 {is_inferred="true"} ! regulation of membrane potential
 is_a: GO:0086004 {is_inferred="true"} ! regulation of cardiac muscle cell contraction
 is_a: GO:0098901 {is_inferred="true"} ! regulation of cardiac muscle cell action potential
 
@@ -61367,7 +61423,6 @@
 id: GO:0098943 ! neurotransmitter receptor transport, postsynaptic endosome to lysosome
 is_a: GO:0007041 {is_inferred="true"} ! lysosomal transport
 is_a: GO:0016197 {is_inferred="true"} ! endosomal transport
-is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
 is_a: GO:0061462 {is_inferred="true"} ! protein localization to lysosome
 is_a: GO:0072666 {is_inferred="true"} ! establishment of protein localization to vacuole
 is_a: GO:0099637 {is_inferred="true"} ! neurotransmitter receptor transport
@@ -61489,7 +61544,6 @@
 id: GO:0098968 ! neurotransmitter receptor transport postsynaptic membrane to endosome
 is_a: GO:0016197 {is_inferred="true"} ! endosomal transport
 is_a: GO:0035418 {is_inferred="true"} ! protein localization to synapse
-is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
 is_a: GO:0072666 {is_inferred="true"} ! establishment of protein localization to vacuole
 is_a: GO:0099637 {is_inferred="true"} ! neurotransmitter receptor transport
 is_a: GO:1902946 {is_inferred="true"} ! protein localization to early endosome
@@ -61816,6 +61870,30 @@
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
 
 [Term]
+id: GO:0099069 ! synaptic vesicle tethering involved in synaptic vesicle exocytosis
+is_a: GO:0090522 {is_inferred="true"} ! vesicle tethering involved in exocytosis
+is_a: GO:0099531 {is_inferred="true"} ! presynaptic process involved in chemical synaptic transmission
+
+[Term]
+id: GO:0099074 ! mitochondrion to lysosome transport
+is_a: GO:0007041 {is_inferred="true"} ! lysosomal transport
+is_a: GO:0099075 {is_inferred="true"} ! mitochondrion-derived vesicle mediated transport
+
+[Term]
+id: GO:0099075 ! mitochondrion-derived vesicle mediated transport
+is_a: GO:0006839 {is_inferred="true"} ! mitochondrial transport
+is_a: GO:0016192 {is_inferred="true"} ! vesicle-mediated transport
+
+[Term]
+id: GO:0099076 ! mitochondrion to peroxisome transport
+is_a: GO:0043574 {is_inferred="true"} ! peroxisomal transport
+is_a: GO:0099075 {is_inferred="true"} ! mitochondrion-derived vesicle mediated transport
+
+[Term]
+id: GO:0099078 ! BORC complex
+is_a: GO:0044445 {is_inferred="true"} ! cytosolic part
+
+[Term]
 id: GO:0099400 ! caveola neck
 is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
 
@@ -61920,6 +61998,10 @@
 is_a: GO:0099509 {is_inferred="true"} ! regulation of presynaptic cytosolic calcium ion concentration
 
 [Term]
+id: GO:0099534 ! calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration
+is_a: GO:0099510 {is_inferred="true"} ! calcium ion binding involved in regulation of cytosolic calcium ion concentration
+
+[Term]
 id: GO:0099539 ! neuropeptide secretion from presynapse
 is_a: GO:0002790 {is_inferred="true"} ! peptide secretion
 
@@ -61978,6 +62060,10 @@
 is_a: GO:1905114 {is_inferred="true"} ! cell surface receptor signaling pathway involved in cell-cell signaling
 
 [Term]
+id: GO:0099567 ! calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration
+is_a: GO:0099510 {is_inferred="true"} ! calcium ion binding involved in regulation of cytosolic calcium ion concentration
+
+[Term]
 id: GO:0099568 ! cytoplasmic region
 is_a: GO:0044444 {is_inferred="true"} ! cytoplasmic part
 
@@ -62187,47 +62273,51 @@
 [Term]
 id: GO:0100002 ! negative regulation of protein kinase activity by protein phosphorylation
 is_a: GO:0006468 {is_inferred="true"} ! protein phosphorylation
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0006469 {is_inferred="true"} ! negative regulation of protein kinase activity
 
 [Term]
 id: GO:0100003 ! positive regulation of sodium ion transport by transcription from RNA polymerase II promoter
+is_a: GO:0010765 {is_inferred="true"} ! positive regulation of sodium ion transport
 is_a: GO:0100020 {is_inferred="true"} ! regulation of transport by transcription from RNA polymerase II promoter
 
 [Term]
 id: GO:0100004 ! positive regulation of peroxisome organization by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:1900064 {is_inferred="true"} ! positive regulation of peroxisome organization
 
 [Term]
 id: GO:0100005 ! positive regulation of ethanol catabolic process by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:1900066 {is_inferred="true"} ! positive regulation of ethanol catabolic process
 
 [Term]
 id: GO:0100006 ! positive regulation of sulfite transport by transcription from RNA polymerase II promoter
 is_a: GO:0100020 {is_inferred="true"} ! regulation of transport by transcription from RNA polymerase II promoter
+is_a: GO:1900072 {is_inferred="true"} ! positive regulation of sulfite transport
 
 [Term]
 id: GO:0100007 ! negative regulation of ceramide biosynthetic process by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:1900060 {is_inferred="true"} ! negative regulation of ceramide biosynthetic process
 
 [Term]
 id: GO:0100008 ! regulation of fever generation by prostaglandin biosynthetic process
 is_a: GO:0001516 {is_inferred="true"} ! prostaglandin biosynthetic process
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0031620 {is_inferred="true"} ! regulation of fever generation
 
 [Term]
 id: GO:0100009 ! regulation of fever generation by prostaglandin secretion
+is_a: GO:0031620 {is_inferred="true"} ! regulation of fever generation
 is_a: GO:0032310 {is_inferred="true"} ! prostaglandin secretion
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
 
 [Term]
 id: GO:0100010 ! positive regulation of fever generation by prostaglandin biosynthetic process
+is_a: GO:0031622 {is_inferred="true"} ! positive regulation of fever generation
 is_a: GO:0100008 {is_inferred="true"} ! regulation of fever generation by prostaglandin biosynthetic process
 
 [Term]
 id: GO:0100011 ! positive regulation of fever generation by prostaglandin secretion
+is_a: GO:0031622 {is_inferred="true"} ! positive regulation of fever generation
 is_a: GO:0100009 {is_inferred="true"} ! regulation of fever generation by prostaglandin secretion
 
 [Term]
@@ -62238,211 +62328,222 @@
 [Term]
 id: GO:0100013 ! positive regulation of fatty acid beta-oxidation by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0032000 {is_inferred="true"} ! positive regulation of fatty acid beta-oxidation
 
 [Term]
 id: GO:0100014 ! positive regulation of mating type switching by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0031496 {is_inferred="true"} ! positive regulation of mating type switching
 
 [Term]
 id: GO:0100015 ! positive regulation of inositol biosynthetic process by transcription from RNA polymerase II promoter
 is_a: GO:0100024 {is_inferred="true"} ! regulation of carbohydrate metabolic process by transcription from RNA polymerase II promoter
+is_a: GO:1900090 {is_inferred="true"} ! positive regulation of inositol biosynthetic process
 
 [Term]
 id: GO:0100016 ! regulation of thiamine biosynthetic process by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0070623 {is_inferred="true"} ! regulation of thiamine biosynthetic process
 
 [Term]
 id: GO:0100017 ! negative regulation of cell-cell adhesion by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0022408 {is_inferred="true"} ! negative regulation of cell-cell adhesion
 
 [Term]
 id: GO:0100018 ! regulation of glucose import by transcription from RNA polymerase II promoter
+is_a: GO:0046324 {is_inferred="true"} ! regulation of glucose import
 is_a: GO:0100020 {is_inferred="true"} ! regulation of transport by transcription from RNA polymerase II promoter
 
 [Term]
 id: GO:0100019 ! regulation of cAMP-mediated signaling by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0043949 {is_inferred="true"} ! regulation of cAMP-mediated signaling
 
 [Term]
 id: GO:0100020 ! regulation of transport by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
 
 [Term]
 id: GO:0100021 ! regulation of iron ion transport by transcription from RNA polymerase II promoter
+is_a: GO:0034756 {is_inferred="true"} ! regulation of iron ion transport
 is_a: GO:0100020 {is_inferred="true"} ! regulation of transport by transcription from RNA polymerase II promoter
 
 [Term]
 id: GO:0100022 ! regulation of iron ion import by transcription from RNA polymerase II promoter
 is_a: GO:0100021 {is_inferred="true"} ! regulation of iron ion transport by transcription from RNA polymerase II promoter
+is_a: GO:1900390 {is_inferred="true"} ! regulation of iron ion import
 
 [Term]
 id: GO:0100023 ! regulation of meiotic nuclear division by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0040020 {is_inferred="true"} ! regulation of meiotic nuclear division
 
 [Term]
 id: GO:0100024 ! regulation of carbohydrate metabolic process by transcription from RNA polymerase II promoter
+is_a: GO:0006109 {is_inferred="true"} ! regulation of carbohydrate metabolic process
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
 
 [Term]
 id: GO:0100025 ! negative regulation of cellular amino acid biosynthetic process by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:2000283 {is_inferred="true"} ! negative regulation of cellular amino acid biosynthetic process
 
 [Term]
 id: GO:0100026 ! positive regulation of DNA repair by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0045739 {is_inferred="true"} ! positive regulation of DNA repair
 
 [Term]
 id: GO:0100027 ! regulation of cell separation after cytokinesis by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0010590 {is_inferred="true"} ! regulation of cell separation after cytokinesis
 
 [Term]
 id: GO:0100028 ! regulation of conjugation with cellular fusion by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0031137 {is_inferred="true"} ! regulation of conjugation with cellular fusion
 
 [Term]
 id: GO:0100032 ! positive regulation of phospholipid biosynthetic process by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0071073 {is_inferred="true"} ! positive regulation of phospholipid biosynthetic process
 
 [Term]
 id: GO:0100033 ! regulation of fungal-type cell wall biogenesis by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0032995 {is_inferred="true"} ! regulation of fungal-type cell wall biogenesis
 
 [Term]
 id: GO:0100034 ! regulation of 4,6-pyruvylated galactose residue biosynthetic process by transcription from RNA polymerase II promoter
+is_a: GO:0060634 {is_inferred="true"} ! regulation of 4,6-pyruvylated galactose residue biosynthetic process
 is_a: GO:0100024 {is_inferred="true"} ! regulation of carbohydrate metabolic process by transcription from RNA polymerase II promoter
 
 [Term]
 id: GO:0100035 ! negative regulation of transmembrane transport by transcription from RNA polymerase II promoter
+is_a: GO:0034763 {is_inferred="true"} ! negative regulation of transmembrane transport
 is_a: GO:0100020 {is_inferred="true"} ! regulation of transport by transcription from RNA polymerase II promoter
 
 [Term]
 id: GO:0100036 ! positive regulation of purine nucleotide biosynthetic process by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:1900373 {is_inferred="true"} ! positive regulation of purine nucleotide biosynthetic process
 
 [Term]
 id: GO:0100037 ! positive regulation of cellular alcohol catabolic process by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:1900421 {is_inferred="true"} ! positive regulation of cellular alcohol catabolic process
 
 [Term]
 id: GO:0100038 ! regulation of cellular response to oxidative stress by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:1900407 {is_inferred="true"} ! regulation of cellular response to oxidative stress
 
 [Term]
 id: GO:0100039 ! regulation of pyrimidine nucleotide biosynthetic process by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:1900397 {is_inferred="true"} ! regulation of pyrimidine nucleotide biosynthetic process
 
 [Term]
 id: GO:0100040 ! negative regulation of invasive growth in response to glucose limitation by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:2000218 {is_inferred="true"} ! negative regulation of invasive growth in response to glucose limitation
 
 [Term]
 id: GO:0100041 ! positive regulation of pseudohyphal growth by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:2000222 {is_inferred="true"} ! positive regulation of pseudohyphal growth
 
 [Term]
 id: GO:0100042 ! negative regulation of pseudohyphal growth by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:2000221 {is_inferred="true"} ! negative regulation of pseudohyphal growth
 
 [Term]
 id: GO:0100043 ! negative regulation of cellular response to alkaline pH by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:1900068 {is_inferred="true"} ! negative regulation of cellular response to alkaline pH
 
 [Term]
 id: GO:0100044 ! negative regulation of cellular hyperosmotic salinity response by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:1900070 {is_inferred="true"} ! negative regulation of cellular hyperosmotic salinity response
 
 [Term]
 id: GO:0100045 ! negative regulation of arginine catabolic process by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:1900082 {is_inferred="true"} ! negative regulation of arginine catabolic process
 
 [Term]
 id: GO:0100046 ! positive regulation of arginine biosynthetic process by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:1900080 {is_inferred="true"} ! positive regulation of arginine biosynthetic process
 
 [Term]
 id: GO:0100047 ! negative regulation of inositol biosynthetic process by transcription from RNA polymerase II promoter
 is_a: GO:0100024 {is_inferred="true"} ! regulation of carbohydrate metabolic process by transcription from RNA polymerase II promoter
+is_a: GO:1900089 {is_inferred="true"} ! negative regulation of inositol biosynthetic process
 
 [Term]
 id: GO:0100048 ! positive regulation of phosphatidylcholine biosynthetic process by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:2001247 {is_inferred="true"} ! positive regulation of phosphatidylcholine biosynthetic process
 
 [Term]
 id: GO:0100049 ! negative regulation of phosphatidylcholine biosynthetic process by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:2001246 {is_inferred="true"} ! negative regulation of phosphatidylcholine biosynthetic process
 
 [Term]
 id: GO:0100050 ! negative regulation of mating type switching by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0031495 {is_inferred="true"} ! negative regulation of mating type switching
 
 [Term]
 id: GO:0100051 ! positive regulation of meiotic nuclear division by transcription from RNA polymerase II promoter
+is_a: GO:0045836 {is_inferred="true"} ! positive regulation of meiotic nuclear division
 is_a: GO:0100023 {is_inferred="true"} ! regulation of meiotic nuclear division by transcription from RNA polymerase II promoter
 
 [Term]
 id: GO:0100052 ! negative regulation of G1/S transition of mitotic cell cycle by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:2000134 {is_inferred="true"} ! negative regulation of G1/S transition of mitotic cell cycle
 
 [Term]
 id: GO:0100053 ! positive regulation of sulfate assimilation by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:1900059 {is_inferred="true"} ! positive regulation of sulfate assimilation
 
 [Term]
 id: GO:0100054 ! positive regulation of flocculation via cell wall protein-carbohydrate interaction by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:1900479 {is_inferred="true"} ! positive regulation of flocculation via cell wall protein-carbohydrate interaction
 
 [Term]
 id: GO:0100055 ! positive regulation of phosphatidylserine biosynthetic process by transcription from RNA polymerase II promoter
 is_a: GO:0100032 {is_inferred="true"} ! positive regulation of phospholipid biosynthetic process by transcription from RNA polymerase II promoter
+is_a: GO:1900470 {is_inferred="true"} ! positive regulation of phosphatidylserine biosynthetic process
 
 [Term]
 id: GO:0100056 ! negative regulation of phosphatidylserine biosynthetic process by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:1900469 {is_inferred="true"} ! negative regulation of phosphatidylserine biosynthetic process
 
 [Term]
 id: GO:0100057 ! regulation of phenotypic switching by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:1900239 {is_inferred="true"} ! regulation of phenotypic switching
 
 [Term]
 id: GO:0100058 ! positive regulation of phenotypic switching by transcription from RNA polymerase II promoter
 is_a: GO:0100057 {is_inferred="true"} ! regulation of phenotypic switching by transcription from RNA polymerase II promoter
+is_a: GO:1900241 {is_inferred="true"} ! positive regulation of phenotypic switching
 
 [Term]
 id: GO:0100059 ! negative regulation of phenotypic switching by transcription from RNA polymerase II promoter
 is_a: GO:0100057 {is_inferred="true"} ! regulation of phenotypic switching by transcription from RNA polymerase II promoter
+is_a: GO:1900240 {is_inferred="true"} ! negative regulation of phenotypic switching
 
 [Term]
 id: GO:0100060 ! negative regulation of SREBP signaling pathway by DNA binding
@@ -62451,28 +62552,31 @@
 [Term]
 id: GO:0100061 ! negative regulation of SREBP signaling pathway by transcription factor catabolic process
 is_a: GO:0036369 {is_inferred="true"} ! transcription factor catabolic process
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:2000639 {is_inferred="true"} ! negative regulation of SREBP signaling pathway
 
 [Term]
 id: GO:0100062 ! positive regulation of SREBP signaling pathway by transcription factor catabolic process
 is_a: GO:0036369 {is_inferred="true"} ! transcription factor catabolic process
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:2000640 {is_inferred="true"} ! positive regulation of SREBP signaling pathway
 
 [Term]
 id: GO:0100063 ! regulation of dipeptide transmembrane transport by transcription from RNA polymerase II promoter
 is_a: GO:0100020 {is_inferred="true"} ! regulation of transport by transcription from RNA polymerase II promoter
+is_a: GO:2001148 {is_inferred="true"} ! regulation of dipeptide transmembrane transport
 
 [Term]
 id: GO:0100064 ! negative regulation of filamentous growth of a population of unicellular organisms in response to starvation by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:1900435 {is_inferred="true"} ! negative regulation of filamentous growth of a population of unicellular organisms in response to starvation
 
 [Term]
 id: GO:0100065 ! negative regulation of leucine import by transcription from RNA polymerase II promoter
+is_a: GO:0060358 {is_inferred="true"} ! negative regulation of leucine import
 is_a: GO:0100020 {is_inferred="true"} ! regulation of transport by transcription from RNA polymerase II promoter
 
 [Term]
 id: GO:0100066 ! negative regulation of induction of conjugation with cellular fusion by transcription from RNA polymerase II promoter
+is_a: GO:0010515 {is_inferred="true"} ! negative regulation of induction of conjugation with cellular fusion
 is_a: GO:0100028 {is_inferred="true"} ! regulation of conjugation with cellular fusion by transcription from RNA polymerase II promoter
 
 [Term]
@@ -62483,17 +62587,17 @@
 [Term]
 id: GO:0100068 ! positive regulation of pyrimidine-containing compound salvage by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:1903931 {is_inferred="true"} ! positive regulation of pyrimidine-containing compound salvage
 
 [Term]
 id: GO:0100069 ! negative regulation of neuron apoptotic process by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0043524 {is_inferred="true"} ! negative regulation of neuron apoptotic process
 
 [Term]
 id: GO:0100070 ! regulation of fatty acid biosynthetic process by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0042304 {is_inferred="true"} ! regulation of fatty acid biosynthetic process
 
 [Term]
 id: GO:0101019 ! nucleolar exosome (RNase complex)
@@ -64415,7 +64519,8 @@
 
 [Term]
 id: GO:1900382 ! regulation of thiamine biosynthetic process by regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
+is_a: GO:0070623 {is_inferred="true"} ! regulation of thiamine biosynthetic process
 
 [Term]
 id: GO:1900383 ! regulation of synaptic plasticity by receptor localization to synapse
@@ -64442,7 +64547,8 @@
 
 [Term]
 id: GO:1900389 ! regulation of glucose import by regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
+is_a: GO:0046324 {is_inferred="true"} ! regulation of glucose import
 
 [Term]
 id: GO:1900390 ! regulation of iron ion import
@@ -64450,15 +64556,18 @@
 
 [Term]
 id: GO:1900391 ! regulation of cAMP-mediated signaling by regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
+is_a: GO:0043949 {is_inferred="true"} ! regulation of cAMP-mediated signaling
 
 [Term]
 id: GO:1900392 ! regulation of transport by negative regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0000122 {is_inferred="true"} ! negative regulation of transcription from RNA polymerase II promoter
+is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
 
 [Term]
 id: GO:1900393 ! regulation of iron ion transport by regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
+is_a: GO:0034756 {is_inferred="true"} ! regulation of iron ion transport
 
 [Term]
 id: GO:1900394 ! regulation of kojic acid biosynthetic process
@@ -64493,15 +64602,18 @@
 
 [Term]
 id: GO:1900400 ! regulation of iron ion import by regulation of transcription from RNA polymerase II promoter
+is_a: GO:1900390 {is_inferred="true"} ! regulation of iron ion import
 is_a: GO:1900393 {is_inferred="true"} ! regulation of iron ion transport by regulation of transcription from RNA polymerase II promoter
 
 [Term]
 id: GO:1900401 ! regulation of meiosis by regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
+is_a: GO:0040020 {is_inferred="true"} ! regulation of meiotic nuclear division
 
 [Term]
 id: GO:1900402 ! regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0006109 {is_inferred="true"} ! regulation of carbohydrate metabolic process
+is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
 
 [Term]
 id: GO:1900403 ! negative regulation of cellular amino acid biosynthetic process by negative regulation of transcription from RNA polymerase II promoter
@@ -64510,11 +64622,13 @@
 
 [Term]
 id: GO:1900404 ! positive regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0006282 {is_inferred="true"} ! regulation of DNA repair
+is_a: GO:0045944 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter
 
 [Term]
 id: GO:1900405 ! regulation of cell separation after cytokinesis by regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
+is_a: GO:0010590 {is_inferred="true"} ! regulation of cell separation after cytokinesis
 
 [Term]
 id: GO:1900406 ! regulation of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter
@@ -64545,14 +64659,17 @@
 
 [Term]
 id: GO:1900415 ! regulation of fungal-type cell wall biogenesis by regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
+is_a: GO:0032995 {is_inferred="true"} ! regulation of fungal-type cell wall biogenesis
 
 [Term]
 id: GO:1900416 ! regulation of 4,6-pyruvylated galactose residue biosynthetic process by regulation of transcription from RNA polymerase II promoter
+is_a: GO:0060634 {is_inferred="true"} ! regulation of 4,6-pyruvylated galactose residue biosynthetic process
 is_a: GO:1900402 {is_inferred="true"} ! regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter
 
 [Term]
 id: GO:1900417 ! negative regulation of transmembrane transport by negative regulation of transcription from RNA polymerase II promoter
+is_a: GO:0034764 {is_inferred="true"} ! positive regulation of transmembrane transport
 is_a: GO:1900392 {is_inferred="true"} ! regulation of transport by negative regulation of transcription from RNA polymerase II promoter
 
 [Term]
@@ -64576,11 +64693,13 @@
 
 [Term]
 id: GO:1900422 ! positive regulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0045944 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter
+is_a: GO:1900419 {is_inferred="true"} ! regulation of cellular alcohol catabolic process
 
 [Term]
 id: GO:1900423 ! positive regulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0031494 {is_inferred="true"} ! regulation of mating type switching
+is_a: GO:0045944 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter
 
 [Term]
 id: GO:1900424 ! regulation of defense response to bacterium
@@ -64607,7 +64726,8 @@
 
 [Term]
 id: GO:1900427 ! regulation of cellular response to oxidative stress by regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
+is_a: GO:1900407 {is_inferred="true"} ! regulation of cellular response to oxidative stress
 
 [Term]
 id: GO:1900428 ! regulation of filamentous growth of a population of unicellular organisms
@@ -64717,7 +64837,8 @@
 
 [Term]
 id: GO:1900448 ! regulation of pyrimidine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
+is_a: GO:1900397 {is_inferred="true"} ! regulation of pyrimidine nucleotide biosynthetic process
 
 [Term]
 id: GO:1900449 ! regulation of glutamate receptor signaling pathway
@@ -64793,7 +64914,10 @@
 
 [Term]
 id: GO:1900465 ! negative regulation of arginine catabolic process by negative regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0033243 {is_inferred="true"} ! positive regulation of cellular amine catabolic process
+is_a: GO:0045764 {is_inferred="true"} ! positive regulation of cellular amino acid metabolic process
+is_a: GO:0072365 {is_inferred="true"} ! regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter
+is_a: GO:1900081 {is_inferred="true"} ! regulation of arginine catabolic process
 
 [Term]
 id: GO:1900466 ! positive regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter
@@ -64840,10 +64964,12 @@
 
 [Term]
 id: GO:1900475 ! positive regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter
+is_a: GO:0000122 {is_inferred="true"} ! negative regulation of transcription from RNA polymerase II promoter
 is_a: GO:1900401 {is_inferred="true"} ! regulation of meiosis by regulation of transcription from RNA polymerase II promoter
 
 [Term]
 id: GO:1900476 ! positive regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter
+is_a: GO:0045944 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter
 is_a: GO:1900401 {is_inferred="true"} ! regulation of meiosis by regulation of transcription from RNA polymerase II promoter
 
 [Term]
@@ -65126,7 +65252,8 @@
 
 [Term]
 id: GO:1900526 ! negative regulation of phosphatidylserine biosynthetic process by negative regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0000122 {is_inferred="true"} ! negative regulation of transcription from RNA polymerase II promoter
+is_a: GO:1900470 {is_inferred="true"} ! positive regulation of phosphatidylserine biosynthetic process
 
 [Term]
 id: GO:1900533 ! palmitic acid metabolic process
@@ -65175,7 +65302,8 @@
 
 [Term]
 id: GO:1900545 ! regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
+is_a: GO:1900239 {is_inferred="true"} ! regulation of phenotypic switching
 
 [Term]
 id: GO:1900546 ! positive regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter
@@ -67306,19 +67434,19 @@
 [Term]
 id: GO:1900920 ! regulation of L-glutamate import
 is_a: GO:0010958 {is_inferred="true"} ! regulation of amino acid import
-is_a: GO:0051955 {is_inferred="true"} ! regulation of amino acid transport
+is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
 
 [Term]
 id: GO:1900921 ! negative regulation of L-glutamate import
-is_a: GO:0032891 {is_inferred="true"} ! negative regulation of organic acid transport
 is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
 is_a: GO:1900920 {is_inferred="true"} ! regulation of L-glutamate import
+is_a: GO:1903792 {is_inferred="true"} ! negative regulation of anion transport
 
 [Term]
 id: GO:1900922 ! positive regulation of L-glutamate import
-is_a: GO:0032892 {is_inferred="true"} ! positive regulation of organic acid transport
 is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
 is_a: GO:1900920 {is_inferred="true"} ! regulation of L-glutamate import
+is_a: GO:1903793 {is_inferred="true"} ! positive regulation of anion transport
 
 [Term]
 id: GO:1900923 ! regulation of glycine import
@@ -67326,12 +67454,12 @@
 
 [Term]
 id: GO:1900924 ! negative regulation of glycine import
-is_a: GO:0032891 {is_inferred="true"} ! negative regulation of organic acid transport
+is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
 is_a: GO:1900923 {is_inferred="true"} ! regulation of glycine import
 
 [Term]
 id: GO:1900925 ! positive regulation of glycine import
-is_a: GO:0032892 {is_inferred="true"} ! positive regulation of organic acid transport
+is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
 is_a: GO:1900923 {is_inferred="true"} ! regulation of glycine import
 
 [Term]
@@ -67340,12 +67468,12 @@
 
 [Term]
 id: GO:1900927 ! negative regulation of L-threonine import
-is_a: GO:0032891 {is_inferred="true"} ! negative regulation of organic acid transport
+is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
 is_a: GO:1900926 {is_inferred="true"} ! regulation of L-threonine import
 
 [Term]
 id: GO:1900928 ! positive regulation of L-threonine import
-is_a: GO:0032892 {is_inferred="true"} ! positive regulation of organic acid transport
+is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
 is_a: GO:1900926 {is_inferred="true"} ! regulation of L-threonine import
 
 [Term]
@@ -67354,12 +67482,12 @@
 
 [Term]
 id: GO:1900930 ! negative regulation of L-tyrosine import
-is_a: GO:0032891 {is_inferred="true"} ! negative regulation of organic acid transport
+is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
 is_a: GO:1900929 {is_inferred="true"} ! regulation of L-tyrosine import
 
 [Term]
 id: GO:1900931 ! positive regulation of L-tyrosine import
-is_a: GO:0032892 {is_inferred="true"} ! positive regulation of organic acid transport
+is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
 is_a: GO:1900929 {is_inferred="true"} ! regulation of L-tyrosine import
 
 [Term]
@@ -67951,12 +68079,12 @@
 
 [Term]
 id: GO:1901035 ! negative regulation of L-glutamine import
-is_a: GO:0032891 {is_inferred="true"} ! negative regulation of organic acid transport
+is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
 is_a: GO:1901034 {is_inferred="true"} ! regulation of L-glutamine import
 
 [Term]
 id: GO:1901036 ! positive regulation of L-glutamine import
-is_a: GO:0032892 {is_inferred="true"} ! positive regulation of organic acid transport
+is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
 is_a: GO:1901034 {is_inferred="true"} ! regulation of L-glutamine import
 
 [Term]
@@ -67983,7 +68111,7 @@
 [Term]
 id: GO:1901042 ! positive regulation of L-arginine import
 is_a: GO:0010963 {is_inferred="true"} ! regulation of L-arginine import
-is_a: GO:0032892 {is_inferred="true"} ! positive regulation of organic acid transport
+is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
 
 [Term]
 id: GO:1901044 ! protein polyubiquitination involved in nucleus-associated proteasomal ubiquitin-dependent protein catabolic process
@@ -70181,7 +70309,8 @@
 
 [Term]
 id: GO:1901488 ! positive regulation of SREBP signaling pathway by negative regulation of transcription factor catabolic process
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:1901484 {is_inferred="true"} ! negative regulation of transcription factor catabolic process
+is_a: GO:2000638 {is_inferred="true"} ! regulation of SREBP signaling pathway
 
 [Term]
 id: GO:1901489 ! positive regulation of SREBP signaling pathway by negative regulation of transcription factor catabolic process in response to decreased oxygen levels
@@ -71312,7 +71441,8 @@
 
 [Term]
 id: GO:1901718 ! regulation of dipeptide transmembrane transport by regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0035953 {is_inferred="true"} ! regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter
+is_a: GO:2001148 {is_inferred="true"} ! regulation of dipeptide transmembrane transport
 
 [Term]
 id: GO:1901720 ! negative regulation of NMS complex assembly involved in kinetochore assembly
@@ -72899,17 +73029,15 @@
 
 [Term]
 id: GO:1902022 ! L-lysine transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
+is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
 
 [Term]
 id: GO:1902023 ! L-arginine transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
-is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
+is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
 
 [Term]
 id: GO:1902024 ! L-histidine transport
-is_a: GO:0015849 {is_inferred="true"} ! organic acid transport
+is_a: GO:0006865 {is_inferred="true"} ! amino acid transport
 is_a: GO:0045117 {is_inferred="true"} ! azole transport
 
 [Term]
@@ -74860,6 +74988,7 @@
 id: GO:1902423 ! regulation of mitotic attachment of spindle microtubules to kinetochore
 is_a: GO:0033047 {is_inferred="true"} ! regulation of mitotic sister chromatid segregation
 is_a: GO:0051988 {is_inferred="true"} ! regulation of attachment of spindle microtubules to kinetochore
+is_a: GO:0090235 {is_inferred="true"} ! regulation of metaphase plate congression
 
 [Term]
 id: GO:1902424 ! negative regulation of mitotic attachment of spindle microtubules to kinetochore
@@ -75549,7 +75678,8 @@
 
 [Term]
 id: GO:1902574 ! negative regulation of leucine import by regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
+is_a: GO:0060357 {is_inferred="true"} ! regulation of leucine import
 
 [Term]
 id: GO:1902575 ! protein localization to cell division site involved in cytokinesis, actomyosin contractile ring assembly
@@ -76743,7 +76873,7 @@
 
 [Term]
 id: GO:1902827 ! negative regulation of L-arginine import into cell
-is_a: GO:0032891 {is_inferred="true"} ! negative regulation of organic acid transport
+is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
 is_a: GO:1902826 {is_inferred="true"} ! regulation of L-arginine import into cell
 
 [Term]
@@ -76781,12 +76911,12 @@
 
 [Term]
 id: GO:1902835 ! negative regulation of proline import into cell
-is_a: GO:0032891 {is_inferred="true"} ! negative regulation of organic acid transport
+is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
 is_a: GO:1902834 {is_inferred="true"} ! regulation of proline import into cell
 
 [Term]
 id: GO:1902836 ! positive regulation of proline import into cell
-is_a: GO:0032892 {is_inferred="true"} ! positive regulation of organic acid transport
+is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
 is_a: GO:1902834 {is_inferred="true"} ! regulation of proline import into cell
 
 [Term]
@@ -76826,7 +76956,9 @@
 
 [Term]
 id: GO:1902844 ! positive regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0050768 {is_inferred="true"} ! negative regulation of neurogenesis
+is_a: GO:0090090 {is_inferred="true"} ! negative regulation of canonical Wnt signaling pathway
+is_a: GO:1902829 {is_inferred="true"} ! regulation of spinal cord association neuron differentiation
 
 [Term]
 id: GO:1902845 ! negative regulation of mitotic spindle elongation
@@ -78220,7 +78352,7 @@
 [Term]
 id: GO:1903125 ! negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation
 is_a: GO:0018107 {is_inferred="true"} ! peptidyl-threonine phosphorylation
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:1903124 {is_inferred="true"} ! negative regulation of thioredoxin peroxidase activity
 
 [Term]
 id: GO:1903126 ! negative regulation of centriole-centriole cohesion
@@ -78243,7 +78375,7 @@
 
 [Term]
 id: GO:1903130 ! positive regulation of leucine import into cell
-is_a: GO:0032892 {is_inferred="true"} ! positive regulation of organic acid transport
+is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
 is_a: GO:1903128 {is_inferred="true"} ! regulation of leucine import into cell
 
 [Term]
@@ -80816,7 +80948,6 @@
 [Term]
 id: GO:1903664 ! regulation of asexual reproduction
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:1903665 ! negative regulation of asexual reproduction
@@ -81065,7 +81196,6 @@
 id: GO:1903712 ! cysteine transmembrane transport
 is_a: GO:0003333 {is_inferred="true"} ! amino acid transmembrane transport
 is_a: GO:0042883 {is_inferred="true"} ! cysteine transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
 id: GO:1903713 ! asparagine transmembrane transport
@@ -81076,7 +81206,6 @@
 id: GO:1903714 ! isoleucine transmembrane transport
 is_a: GO:0003333 {is_inferred="true"} ! amino acid transmembrane transport
 is_a: GO:0015818 {is_inferred="true"} ! isoleucine transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
 id: GO:1903715 ! regulation of aerobic respiration
@@ -81246,15 +81375,17 @@
 
 [Term]
 id: GO:1903756 ! regulation of transcription from RNA polymerase II promoter by histone modification
+is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
 is_a: GO:0016570 {is_inferred="true"} ! histone modification
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
 
 [Term]
 id: GO:1903757 ! positive regulation of transcription from RNA polymerase II promoter by histone modification
+is_a: GO:0045944 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter
 is_a: GO:1903756 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter by histone modification
 
 [Term]
 id: GO:1903758 ! negative regulation of transcription from RNA polymerase II promoter by histone modification
+is_a: GO:0000122 {is_inferred="true"} ! negative regulation of transcription from RNA polymerase II promoter
 is_a: GO:1903756 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter by histone modification
 
 [Term]
@@ -81415,8 +81546,8 @@
 
 [Term]
 id: GO:1903789 ! regulation of amino acid transmembrane transport
-is_a: GO:0032890 {is_inferred="true"} ! regulation of organic acid transport
 is_a: GO:0034762 {is_inferred="true"} ! regulation of transmembrane transport
+is_a: GO:0051955 {is_inferred="true"} ! regulation of amino acid transport
 
 [Term]
 id: GO:1903790 ! guanine nucleotide transmembrane transport
@@ -82431,7 +82562,8 @@
 
 [Term]
 id: GO:1904001 ! positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0045944 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter
+is_a: GO:1903930 {is_inferred="true"} ! regulation of pyrimidine-containing compound salvage
 
 [Term]
 id: GO:1904002 ! regulation of sebum secreting cell proliferation
@@ -84656,6 +84788,7 @@
 
 [Term]
 id: GO:1904448 ! regulation of aspartate secretion
+is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
 is_a: GO:0051955 {is_inferred="true"} ! regulation of amino acid transport
 is_a: GO:1903530 {is_inferred="true"} ! regulation of secretion by cell
 
@@ -84663,6 +84796,7 @@
 id: GO:1904449 ! negative regulation of aspartate secretion
 is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
 is_a: GO:1903531 {is_inferred="true"} ! negative regulation of secretion by cell
+is_a: GO:1903792 {is_inferred="true"} ! negative regulation of anion transport
 is_a: GO:1904448 {is_inferred="true"} ! regulation of aspartate secretion
 
 [Term]
@@ -84669,6 +84803,7 @@
 id: GO:1904450 ! positive regulation of aspartate secretion
 is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
 is_a: GO:1903532 {is_inferred="true"} ! positive regulation of secretion by cell
+is_a: GO:1903793 {is_inferred="true"} ! positive regulation of anion transport
 is_a: GO:1904448 {is_inferred="true"} ! regulation of aspartate secretion
 
 [Term]
@@ -85496,14 +85631,14 @@
 
 [Term]
 id: GO:1904624 ! regulation of glycine secretion, neurotransmission
-is_a: GO:0032890 {is_inferred="true"} ! regulation of organic acid transport
 is_a: GO:0046928 {is_inferred="true"} ! regulation of neurotransmitter secretion
+is_a: GO:0051955 {is_inferred="true"} ! regulation of amino acid transport
 is_a: GO:0060092 {is_inferred="true"} ! regulation of synaptic transmission, glycinergic
 
 [Term]
 id: GO:1904625 ! negative regulation of glycine secretion, neurotransmission
-is_a: GO:0032891 {is_inferred="true"} ! negative regulation of organic acid transport
 is_a: GO:0046929 {is_inferred="true"} ! negative regulation of neurotransmitter secretion
+is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
 is_a: GO:0060093 {is_inferred="true"} ! negative regulation of synaptic transmission, glycinergic
 is_a: GO:1904624 {is_inferred="true"} ! regulation of glycine secretion, neurotransmission
 
@@ -85510,7 +85645,7 @@
 [Term]
 id: GO:1904626 ! positive regulation of glycine secretion, neurotransmission
 is_a: GO:0001956 {is_inferred="true"} ! positive regulation of neurotransmitter secretion
-is_a: GO:0032892 {is_inferred="true"} ! positive regulation of organic acid transport
+is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
 is_a: GO:0060094 {is_inferred="true"} ! positive regulation of synaptic transmission, glycinergic
 is_a: GO:1904624 {is_inferred="true"} ! regulation of glycine secretion, neurotransmission
 
@@ -86077,7 +86212,7 @@
 [Term]
 id: GO:1904740 ! positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:1900436 {is_inferred="true"} ! positive regulation of filamentous growth of a population of unicellular organisms in response to starvation
 
 [Term]
 id: GO:1904741 ! positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of transcription from RNA polymerase II promoter
@@ -87381,7 +87516,7 @@
 
 [Term]
 id: GO:1905010 ! positive regulation of L-lysine import into cell
-is_a: GO:0032892 {is_inferred="true"} ! positive regulation of organic acid transport
+is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
 is_a: GO:1905008 {is_inferred="true"} ! regulation of L-lysine import into cell
 
 [Term]
@@ -87471,11 +87606,8 @@
 
 [Term]
 id: GO:1905027 ! regulation of membrane depolarization during AV node cell action potential
-is_a: GO:0003254 {is_inferred="true"} ! regulation of membrane depolarization
-is_a: GO:0010646 {is_inferred="true"} ! regulation of cell communication
 is_a: GO:0098904 {is_inferred="true"} ! regulation of AV node cell action potential
 is_a: GO:1900825 {is_inferred="true"} ! regulation of membrane depolarization during cardiac muscle cell action potential
-is_a: GO:1903779 {is_inferred="true"} ! regulation of cardiac conduction
 
 [Term]
 id: GO:1905028 ! negative regulation of membrane depolarization during AV node cell action potential
@@ -87903,7 +88035,6 @@
 
 [Term]
 id: GO:1905115 ! regulation of lateral attachment of mitotic spindle microtubules to kinetochore
-is_a: GO:0090235 {is_inferred="true"} ! regulation of metaphase plate congression
 is_a: GO:1902423 {is_inferred="true"} ! regulation of mitotic attachment of spindle microtubules to kinetochore
 
 [Term]
@@ -89121,19 +89252,19 @@
 
 [Term]
 id: GO:1905365 ! regulation of intralumenal vesicle formation
-is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
 is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
+is_a: GO:1904978 {is_inferred="true"} ! regulation of endosome organization
 
 [Term]
 id: GO:1905366 ! negative regulation of intralumenal vesicle formation
-is_a: GO:0010639 {is_inferred="true"} ! negative regulation of organelle organization
 is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
+is_a: GO:1904979 {is_inferred="true"} ! negative regulation of endosome organization
 is_a: GO:1905365 {is_inferred="true"} ! regulation of intralumenal vesicle formation
 
 [Term]
 id: GO:1905367 ! positive regulation of intralumenal vesicle formation
-is_a: GO:0010638 {is_inferred="true"} ! positive regulation of organelle organization
 is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
+is_a: GO:1904980 {is_inferred="true"} ! positive regulation of endosome organization
 is_a: GO:1905365 {is_inferred="true"} ! regulation of intralumenal vesicle formation
 
 [Term]
@@ -89702,6 +89833,11 @@
 is_a: GO:0030936 {is_inferred="true"} ! transmembrane collagen trimer
 
 [Term]
+id: GO:1990331 ! Hpa2 acetyltransferase complex
+is_a: GO:0070775 {is_inferred="true"} ! H3 histone acetyltransferase complex
+is_a: GO:1902562 {is_inferred="true"} ! H4 histone acetyltransferase complex
+
+[Term]
 id: GO:1990332 ! Ire1 complex
 is_a: GO:0044432 {is_inferred="true"} ! endoplasmic reticulum part
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
@@ -89854,6 +89990,10 @@
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
+id: GO:1990520 ! separase-securin complex
+is_a: GO:1905369 {is_inferred="true"} ! endopeptidase complex
+
+[Term]
 id: GO:1990524 ! INA complex
 is_a: GO:0098800 {is_inferred="true"} ! inner mitochondrial membrane protein complex
 
@@ -90010,6 +90150,10 @@
 is_a: GO:1903713 {is_inferred="true"} ! asparagine transmembrane transport
 
 [Term]
+id: GO:1990598 ! repair of mitotic mono-orientation defects
+is_a: GO:0022402 {is_inferred="true"} ! cell cycle process
+
+[Term]
 id: GO:1990604 ! IRE1-TRAF2-ASK1 complex
 is_a: GO:0044432 {is_inferred="true"} ! endoplasmic reticulum part
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
@@ -90139,7 +90283,7 @@
 
 [Term]
 id: GO:1990758 ! mitotic sister chromatid biorientation
-is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
+is_a: GO:0031134 {is_inferred="true"} ! sister chromatid biorientation
 
 [Term]
 id: GO:1990761 ! growth cone lamellipodium
@@ -90210,7 +90354,7 @@
 
 [Term]
 id: GO:1990822 ! basic amino acid transmembrane transport
-is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
+is_a: GO:0003333 {is_inferred="true"} ! amino acid transmembrane transport
 
 [Term]
 id: GO:1990849 ! maintenance of vacuolar location
@@ -91566,7 +91710,6 @@
 [Term]
 id: GO:2000241 ! regulation of reproductive process
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
 id: GO:2000242 ! negative regulation of reproductive process
@@ -92818,16 +92961,19 @@
 
 [Term]
 id: GO:2000485 ! regulation of glutamine transport
+is_a: GO:0044070 {is_inferred="true"} ! regulation of anion transport
 is_a: GO:0051955 {is_inferred="true"} ! regulation of amino acid transport
 
 [Term]
 id: GO:2000486 ! negative regulation of glutamine transport
 is_a: GO:0051956 {is_inferred="true"} ! negative regulation of amino acid transport
+is_a: GO:1903792 {is_inferred="true"} ! negative regulation of anion transport
 is_a: GO:2000485 {is_inferred="true"} ! regulation of glutamine transport
 
 [Term]
 id: GO:2000487 ! positive regulation of glutamine transport
 is_a: GO:0051957 {is_inferred="true"} ! positive regulation of amino acid transport
+is_a: GO:1903793 {is_inferred="true"} ! positive regulation of anion transport
 is_a: GO:2000485 {is_inferred="true"} ! regulation of glutamine transport
 
 [Term]
@@ -93024,7 +93170,8 @@
 
 [Term]
 id: GO:2000531 ! regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
+is_a: GO:0042304 {is_inferred="true"} ! regulation of fatty acid biosynthetic process
+is_a: GO:0072364 {is_inferred="true"} ! regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter
 
 [Term]
 id: GO:2000532 ! regulation of renal albumin absorption
@@ -96654,11 +96801,13 @@
 [Term]
 id: GO:2001248 ! regulation of ammonia assimilation cycle
 is_a: GO:0006521 {is_inferred="true"} ! regulation of cellular amino acid metabolic process
+is_a: GO:0006808 {is_inferred="true"} ! regulation of nitrogen utilization
 is_a: GO:2000211 {is_inferred="true"} ! regulation of glutamate metabolic process
 
 [Term]
 id: GO:2001249 ! negative regulation of ammonia assimilation cycle
 is_a: GO:0045763 {is_inferred="true"} ! negative regulation of cellular amino acid metabolic process
+is_a: GO:0045847 {is_inferred="true"} ! negative regulation of nitrogen utilization
 is_a: GO:2000212 {is_inferred="true"} ! negative regulation of glutamate metabolic process
 is_a: GO:2001248 {is_inferred="true"} ! regulation of ammonia assimilation cycle
 
@@ -96665,6 +96814,7 @@
 [Term]
 id: GO:2001250 ! positive regulation of ammonia assimilation cycle
 is_a: GO:0045764 {is_inferred="true"} ! positive regulation of cellular amino acid metabolic process
+is_a: GO:0045848 {is_inferred="true"} ! positive regulation of nitrogen utilization
 is_a: GO:2000213 {is_inferred="true"} ! positive regulation of glutamate metabolic process
 is_a: GO:2001248 {is_inferred="true"} ! regulation of ammonia assimilation cycle
 
------------------------------------------------------------------------
r35175 | paola | 2016-08-26 07:06:47 -0700 (Fri, 26 Aug 2016) | 3 lines

GH complement receptor merges ? #12579 - work in progress - see ticket for details

changes in entailments

------------------------------------------------------------------------
r35166 | tberardi | 2016-08-25 17:51:09 -0700 (Thu, 25 Aug 2016) | 1 line

incremental progress is separating plant organ development and animal organ development children terms

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35166)
+++ go_inferences.obo	(working copy)
@@ -4254,7 +4254,7 @@
 is_a: GO:0003154 {is_inferred="true"} ! BMP signaling pathway involved in determination of left/right symmetry
 
 [Term]
-id: GO:0003156 ! regulation of organ formation
+id: GO:0003156 ! regulation of animal organ formation
 is_a: GO:2000027 {is_inferred="true"} ! regulation of organ morphogenesis
 
 [Term]
@@ -4392,7 +4392,7 @@
 
 [Term]
 id: GO:0003264 ! regulation of cardioblast proliferation
-is_a: GO:0003156 {is_inferred="true"} ! regulation of organ formation
+is_a: GO:0003156 {is_inferred="true"} ! regulation of animal organ formation
 is_a: GO:2000136 {is_inferred="true"} ! regulation of cell proliferation involved in heart morphogenesis
 
 [Term]
@@ -10968,6 +10968,7 @@
 
 [Term]
 id: GO:0009878 ! nodule morphogenesis
+is_a: GO:0009653 {is_inferred="true"} ! anatomical structure morphogenesis
 is_a: GO:0044111 {is_inferred="true"} ! development involved in symbiotic interaction
 
 [Term]
@@ -19894,7 +19895,7 @@
 
 [Term]
 id: GO:0022612 ! gland morphogenesis
-is_a: GO:0009887 {is_inferred="true"} ! organ morphogenesis
+is_a: GO:0009887 {is_inferred="true"} ! animal organ morphogenesis
 
 [Term]
 id: GO:0022617 ! extracellular matrix disassembly
@@ -37908,7 +37909,7 @@
 
 [Term]
 id: GO:0045704 ! regulation of salivary gland boundary specification
-is_a: GO:0003156 {is_inferred="true"} ! regulation of organ formation
+is_a: GO:0003156 {is_inferred="true"} ! regulation of animal organ formation
 
 [Term]
 id: GO:0045705 ! negative regulation of salivary gland boundary specification
@@ -42796,16 +42797,12 @@
 is_a: GO:0048827 {is_inferred="true"} ! phyllome development
 
 [Term]
-id: GO:0048444 ! floral organ morphogenesis
-is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:1905392 {is_inferred="true"} ! plant organ morphogenesis
-
-[Term]
 id: GO:0048449 ! floral organ formation
 is_a: GO:1905393 {is_inferred="true"} ! plant organ formation
 
 [Term]
 id: GO:0048450 ! floral organ structural organization
+is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:0048532 {is_inferred="true"} ! anatomical structure arrangement
 
 [Term]
@@ -48349,7 +48346,7 @@
 
 [Term]
 id: GO:0060349 ! bone morphogenesis
-is_a: GO:0009887 {is_inferred="true"} ! organ morphogenesis
+is_a: GO:0009887 {is_inferred="true"} ! animal organ morphogenesis
 
 [Term]
 id: GO:0060351 ! cartilage development involved in endochondral bone morphogenesis
@@ -48810,7 +48807,7 @@
 
 [Term]
 id: GO:0060536 ! cartilage morphogenesis
-is_a: GO:0009887 {is_inferred="true"} ! organ morphogenesis
+is_a: GO:0009887 {is_inferred="true"} ! animal organ morphogenesis
 
 [Term]
 id: GO:0060542 ! regulation of strand invasion
@@ -49199,7 +49196,7 @@
 
 [Term]
 id: GO:0060685 ! regulation of prostatic bud formation
-is_a: GO:0003156 {is_inferred="true"} ! regulation of organ formation
+is_a: GO:0003156 {is_inferred="true"} ! regulation of animal organ formation
 is_a: GO:0045995 {is_inferred="true"} ! regulation of embryonic development
 is_a: GO:0060688 {is_inferred="true"} ! regulation of morphogenesis of a branching structure
 is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
@@ -50963,11 +50960,11 @@
 
 [Term]
 id: GO:0061552 ! ganglion morphogenesis
-is_a: GO:0009887 {is_inferred="true"} ! organ morphogenesis
+is_a: GO:0009887 {is_inferred="true"} ! animal organ morphogenesis
 
 [Term]
 id: GO:0061553 ! ganglion maturation
-is_a: GO:0048799 {is_inferred="true"} ! organ maturation
+is_a: GO:0048799 {is_inferred="true"} ! animal organ maturation
 
 [Term]
 id: GO:0061610 ! glycerol to glycerone phosphate metabolic process
@@ -53183,7 +53180,7 @@
 
 [Term]
 id: GO:0070977 ! bone maturation
-is_a: GO:0048799 {is_inferred="true"} ! organ maturation
+is_a: GO:0048799 {is_inferred="true"} ! animal organ maturation
 
 [Term]
 id: GO:0070980 ! biphenyl catabolic process
@@ -55555,7 +55552,7 @@
 
 [Term]
 id: GO:0072116 ! pronephros formation
-is_a: GO:0048645 {is_inferred="true"} ! organ formation
+is_a: GO:0048645 {is_inferred="true"} ! animal organ formation
 
 [Term]
 id: GO:0072124 ! regulation of glomerular mesangial cell proliferation
@@ -59298,7 +59295,7 @@
 
 [Term]
 id: GO:0090381 ! regulation of heart induction
-is_a: GO:0003156 {is_inferred="true"} ! regulation of organ formation
+is_a: GO:0003156 {is_inferred="true"} ! regulation of animal organ formation
 is_a: GO:2000826 {is_inferred="true"} ! regulation of heart morphogenesis
 
 [Term]
@@ -59569,7 +59566,7 @@
 
 [Term]
 id: GO:0090596 ! sensory organ morphogenesis
-is_a: GO:0009887 {is_inferred="true"} ! organ morphogenesis
+is_a: GO:0009887 {is_inferred="true"} ! animal organ morphogenesis
 
 [Term]
 id: GO:0090598 ! male anatomical structure morphogenesis
@@ -59596,6 +59593,10 @@
 is_a: GO:0032155 {is_inferred="true"} ! cell division site part
 
 [Term]
+id: GO:0090696 ! post-embryonic plant organ development
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
+
+[Term]
 id: GO:0093001 ! glycolysis from storage polysaccharide through glucose-1-phosphate
 is_a: GO:0000272 {is_inferred="true"} ! polysaccharide catabolic process
 is_a: GO:0061622 {is_inferred="true"} ! glycolytic process through glucose-1-phosphate
@@ -69606,7 +69607,6 @@
 id: GO:1901371 ! regulation of leaf morphogenesis
 is_a: GO:1900618 {is_inferred="true"} ! regulation of shoot system morphogenesis
 is_a: GO:2000024 {is_inferred="true"} ! regulation of leaf development
-is_a: GO:2000027 {is_inferred="true"} ! regulation of organ morphogenesis
 
 [Term]
 id: GO:1901372 ! trehalose biosynthetic process involved in ascospore formation
------------------------------------------------------------------------
r35164 | tberardi | 2016-08-25 16:28:46 -0700 (Thu, 25 Aug 2016) | 1 line

removed link between spore-bearing organ development and animal organ development

changes in entailments

------------------------------------------------------------------------
r35157 | termgenie | 2016-08-25 09:58:55 -0700 (Thu, 25 Aug 2016) | 3 lines

TermGenie commit for user: vw reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35157)
+++ go_inferences.obo	(working copy)
@@ -89336,6 +89336,17 @@
 is_a: GO:1905407 {is_inferred="true"} ! regulation of creatine transmembrane transporter activity
 
 [Term]
+id: GO:1905410 ! regulation of mitotic cohesin unloading
+is_a: GO:0007346 {is_inferred="true"} ! regulation of mitotic cell cycle
+is_a: GO:1905343 {is_inferred="true"} ! regulation of cohesin unloading
+
+[Term]
+id: GO:1905411 ! positive regulation of mitotic cohesin unloading
+is_a: GO:0045931 {is_inferred="true"} ! positive regulation of mitotic cell cycle
+is_a: GO:1905339 {is_inferred="true"} ! positive regulation of cohesin unloading
+is_a: GO:1905410 {is_inferred="true"} ! regulation of mitotic cohesin unloading
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35155 | termgenie | 2016-08-25 09:39:19 -0700 (Thu, 25 Aug 2016) | 4 lines

TermGenie commit for user: bc reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35155)
+++ go_inferences.obo	(working copy)
@@ -89281,6 +89281,61 @@
 is_a: GO:0070231 {is_inferred="true"} ! T cell apoptotic process
 
 [Term]
+id: GO:1905399 ! regulation of activated CD4-positive, alpha-beta T cell apoptotic process
+is_a: GO:0070232 {is_inferred="true"} ! regulation of T cell apoptotic process
+
+[Term]
+id: GO:1905400 ! negative regulation of activated CD4-positive, alpha-beta T cell apoptotic process
+is_a: GO:0070233 {is_inferred="true"} ! negative regulation of T cell apoptotic process
+is_a: GO:1905399 {is_inferred="true"} ! regulation of activated CD4-positive, alpha-beta T cell apoptotic process
+
+[Term]
+id: GO:1905401 ! positive regulation of activated CD4-positive, alpha-beta T cell apoptotic process
+is_a: GO:0070234 {is_inferred="true"} ! positive regulation of T cell apoptotic process
+is_a: GO:1905399 {is_inferred="true"} ! regulation of activated CD4-positive, alpha-beta T cell apoptotic process
+
+[Term]
+id: GO:1905402 ! regulation of activated CD8-positive, alpha-beta T cell apoptotic process
+is_a: GO:0070232 {is_inferred="true"} ! regulation of T cell apoptotic process
+
+[Term]
+id: GO:1905403 ! negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process
+is_a: GO:0070233 {is_inferred="true"} ! negative regulation of T cell apoptotic process
+is_a: GO:1905402 {is_inferred="true"} ! regulation of activated CD8-positive, alpha-beta T cell apoptotic process
+
+[Term]
+id: GO:1905404 ! positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process
+is_a: GO:0070234 {is_inferred="true"} ! positive regulation of T cell apoptotic process
+is_a: GO:1905402 {is_inferred="true"} ! regulation of activated CD8-positive, alpha-beta T cell apoptotic process
+
+[Term]
+id: GO:1905405 ! regulation of mitotic cohesin loading
+is_a: GO:0033047 {is_inferred="true"} ! regulation of mitotic sister chromatid segregation
+is_a: GO:0071922 {is_inferred="true"} ! regulation of cohesin loading
+
+[Term]
+id: GO:1905406 ! positive regulation of mitotic cohesin loading
+is_a: GO:0045840 {is_inferred="true"} ! positive regulation of mitotic nuclear division
+is_a: GO:1905309 {is_inferred="true"} ! positive regulation of cohesin loading
+is_a: GO:1905405 {is_inferred="true"} ! regulation of mitotic cohesin loading
+
+[Term]
+id: GO:1905407 ! regulation of creatine transmembrane transporter activity
+is_a: GO:0022898 {is_inferred="true"} ! regulation of transmembrane transporter activity
+
+[Term]
+id: GO:1905408 ! negative regulation of creatine transmembrane transporter activity
+is_a: GO:0032410 {is_inferred="true"} ! negative regulation of transporter activity
+is_a: GO:0034763 {is_inferred="true"} ! negative regulation of transmembrane transport
+is_a: GO:1905407 {is_inferred="true"} ! regulation of creatine transmembrane transporter activity
+
+[Term]
+id: GO:1905409 ! positive regulation of creatine transmembrane transporter activity
+is_a: GO:0032411 {is_inferred="true"} ! positive regulation of transporter activity
+is_a: GO:0034764 {is_inferred="true"} ! positive regulation of transmembrane transport
+is_a: GO:1905407 {is_inferred="true"} ! regulation of creatine transmembrane transporter activity
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35145 | paola | 2016-08-25 07:58:12 -0700 (Thu, 25 Aug 2016) | 3 lines

Additional taxon checks? #12581 - work in progress - restricted ‘calcineurin-NFAT signaling cascade’ and ‘Wnt signaling pathway’ to ‘only in Metazoa’

changes in entailments

------------------------------------------------------------------------
r35143 | paola | 2016-08-25 07:29:37 -0700 (Thu, 25 Aug 2016) | 2 lines

Fixing build again

changes in entailments

------------------------------------------------------------------------
r35140 | mcourtot | 2016-08-25 07:21:58 -0700 (Thu, 25 Aug 2016) | 1 line

removed wrong subclass of protein complex for id: GO:1990332

changes in entailments

------------------------------------------------------------------------
r35138 | paola | 2016-08-25 06:41:17 -0700 (Thu, 25 Aug 2016) | 2 lines

Fixing xref errors again - will alert Chris as they keep coming in

changes in entailments

------------------------------------------------------------------------
r35131 | paola | 2016-08-25 05:41:49 -0700 (Thu, 25 Aug 2016) | 2 lines

Trying to fix another build error

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35131)
+++ go_inferences.obo	(working copy)
@@ -24413,6 +24413,10 @@
 is_a: GO:0032530 {is_inferred="true"} ! regulation of microvillus organization
 
 [Term]
+id: GO:0032533 ! regulation of follicle cell microvillus length
+is_a: GO:0008361 {is_inferred="true"} ! regulation of cell size
+
+[Term]
 id: GO:0032534 ! regulation of microvillus assembly
 is_a: GO:0032530 {is_inferred="true"} ! regulation of microvillus organization
 is_a: GO:0060491 {is_inferred="true"} ! regulation of cell projection assembly
@@ -42349,10 +42353,6 @@
 is_a: GO:0048145 {is_inferred="true"} ! regulation of fibroblast proliferation
 
 [Term]
-id: GO:0048167 ! regulation of synaptic plasticity
-is_a: GO:0050803 {is_inferred="true"} ! regulation of synapse structure or activity
-
-[Term]
 id: GO:0048175 ! hepatocyte growth factor biosynthetic process
 is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
 
------------------------------------------------------------------------
r35121 | termgenie | 2016-08-25 01:56:54 -0700 (Thu, 25 Aug 2016) | 2 lines

TermGenie commit for user: pga reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35121)
+++ go_inferences.obo	(working copy)
@@ -89273,6 +89273,14 @@
 is_a: GO:1905395 {is_inferred="true"} ! response to flavonoid
 
 [Term]
+id: GO:1905397 ! activated CD8-positive, alpha-beta T cell apoptotic process
+is_a: GO:0070231 {is_inferred="true"} ! T cell apoptotic process
+
+[Term]
+id: GO:1905398 ! activated CD4-positive, alpha-beta T cell apoptotic process
+is_a: GO:0070231 {is_inferred="true"} ! T cell apoptotic process
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35118 | mcourtot | 2016-08-25 01:37:45 -0700 (Thu, 25 Aug 2016) | 1 line

added GOC:gg to GO:0097718. Closes https://github.com/geneontology/go-ontology/issues/12585

changes in entailments

------------------------------------------------------------------------
r35114 | cjm | 2016-08-24 17:41:54 -0700 (Wed, 24 Aug 2016) | 1 line

axiomatizing fungal terms using FAO

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35115)
+++ go_inferences.obo	(working copy)
@@ -1205,6 +1205,10 @@
 is_a: GO:0015216 {is_inferred="true"} ! purine nucleotide transmembrane transporter activity
 
 [Term]
+id: GO:0001411 ! hyphal tip
+is_a: GO:0030427 {is_inferred="true"} ! site of polarized growth
+
+[Term]
 id: GO:0001504 ! neurotransmitter uptake
 is_a: GO:0098657 {is_inferred="true"} ! import into cell
 
@@ -20570,6 +20574,10 @@
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
 
 [Term]
+id: GO:0030446 ! hyphal cell wall
+is_a: GO:0009277 {is_inferred="true"} ! fungal-type cell wall
+
+[Term]
 id: GO:0030449 ! regulation of complement activation
 is_a: GO:0002697 {is_inferred="true"} ! regulation of immune effector process
 is_a: GO:0002920 {is_inferred="true"} ! regulation of humoral immune response
@@ -23426,6 +23434,10 @@
 is_a: GO:0044463 {is_inferred="true"} ! cell projection part
 
 [Term]
+id: GO:0032168 ! hyphal septin ring
+is_a: GO:0005940 {is_inferred="true"} ! septin ring
+
+[Term]
 id: GO:0032169 ! prospore septin ring
 is_a: GO:0005940 {is_inferred="true"} ! septin ring
 
@@ -56979,16 +56991,23 @@
 is_a: GO:0075288 {is_inferred="true"} ! negative regulation of sporangiospore formation
 
 [Term]
+id: GO:0075243 ! oospore formation
+is_a: GO:0044711 {is_inferred="true"} ! single-organism biosynthetic process
+
+[Term]
 id: GO:0075244 ! regulation of oospore formation
+is_a: GO:0009889 {is_inferred="true"} ! regulation of biosynthetic process
 is_a: GO:0043940 {is_inferred="true"} ! regulation of sexual sporulation resulting in formation of a cellular spore
 
 [Term]
 id: GO:0075245 ! positive regulation of oospore formation
+is_a: GO:0009891 {is_inferred="true"} ! positive regulation of biosynthetic process
 is_a: GO:0043941 {is_inferred="true"} ! positive regulation of sexual sporulation resulting in formation of a cellular spore
 is_a: GO:0075244 {is_inferred="true"} ! regulation of oospore formation
 
 [Term]
 id: GO:0075246 ! negative regulation of oospore formation
+is_a: GO:0009890 {is_inferred="true"} ! negative regulation of biosynthetic process
 is_a: GO:0043942 {is_inferred="true"} ! negative regulation of sexual sporulation resulting in formation of a cellular spore
 is_a: GO:0075244 {is_inferred="true"} ! regulation of oospore formation
 
@@ -57007,30 +57026,44 @@
 is_a: GO:0075248 {is_inferred="true"} ! regulation of aeciospore formation
 
 [Term]
+id: GO:0075251 ! uredospore formation
+is_a: GO:0044711 {is_inferred="true"} ! single-organism biosynthetic process
+
+[Term]
 id: GO:0075252 ! regulation of uredospore formation
+is_a: GO:0009889 {is_inferred="true"} ! regulation of biosynthetic process
 is_a: GO:0043943 {is_inferred="true"} ! regulation of asexual sporulation resulting in formation of a cellular spore
 
 [Term]
 id: GO:0075253 ! positive regulation of uredospore formation
+is_a: GO:0009891 {is_inferred="true"} ! positive regulation of biosynthetic process
 is_a: GO:0043945 {is_inferred="true"} ! positive regulation of asexual sporulation resulting in formation of a cellular spore
 is_a: GO:0075252 {is_inferred="true"} ! regulation of uredospore formation
 
 [Term]
 id: GO:0075254 ! negative regulation of uredospore formation
+is_a: GO:0009890 {is_inferred="true"} ! negative regulation of biosynthetic process
 is_a: GO:0043944 {is_inferred="true"} ! negative regulation of asexual sporulation resulting in formation of a cellular spore
 is_a: GO:0075252 {is_inferred="true"} ! regulation of uredospore formation
 
 [Term]
+id: GO:0075255 ! teliospore formation
+is_a: GO:0044711 {is_inferred="true"} ! single-organism biosynthetic process
+
+[Term]
 id: GO:0075256 ! regulation of teliospore formation
+is_a: GO:0009889 {is_inferred="true"} ! regulation of biosynthetic process
 is_a: GO:0043943 {is_inferred="true"} ! regulation of asexual sporulation resulting in formation of a cellular spore
 
 [Term]
 id: GO:0075257 ! positive regulation of teliospore formation
+is_a: GO:0009891 {is_inferred="true"} ! positive regulation of biosynthetic process
 is_a: GO:0043945 {is_inferred="true"} ! positive regulation of asexual sporulation resulting in formation of a cellular spore
 is_a: GO:0075256 {is_inferred="true"} ! regulation of teliospore formation
 
 [Term]
 id: GO:0075258 ! negative regulation of teliospore formation
+is_a: GO:0009890 {is_inferred="true"} ! negative regulation of biosynthetic process
 is_a: GO:0043944 {is_inferred="true"} ! negative regulation of asexual sporulation resulting in formation of a cellular spore
 is_a: GO:0075256 {is_inferred="true"} ! regulation of teliospore formation
 
------------------------------------------------------------------------
r35111 | tberardi | 2016-08-24 17:13:58 -0700 (Wed, 24 Aug 2016) | 1 line

GH12609 GO:0032116 SMC loading complex name change - closed

changes in entailments

------------------------------------------------------------------------
r35111 | tberardi | 2016-08-24 17:13:58 -0700 (Wed, 24 Aug 2016) | 1 line

GH12609 GO:0032116 SMC loading complex name change - closed

changes in entailments

------------------------------------------------------------------------
r35106 | tberardi | 2016-08-24 11:11:31 -0700 (Wed, 24 Aug 2016) | 1 line

GH12578 - incremental progress in cleaning up animal organ and plant organ development split

changes in entailments

------------------------------------------------------------------------
r35106 | tberardi | 2016-08-24 11:11:31 -0700 (Wed, 24 Aug 2016) | 1 line

GH12578 - incremental progress in cleaning up animal organ and plant organ development split

changes in entailments

------------------------------------------------------------------------
r35104 | tberardi | 2016-08-24 10:49:07 -0700 (Wed, 24 Aug 2016) | 1 line

GH12611 NTR: mitochondrial membrane scission site - closed

changes in entailments

------------------------------------------------------------------------
r35102 | tberardi | 2016-08-24 10:44:12 -0700 (Wed, 24 Aug 2016) | 1 line

GH12612 - Synonym request for GO:0090149 mitochondrial membrane fission - closed

changes in entailments

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r35100 | tberardi | 2016-08-24 10:33:23 -0700 (Wed, 24 Aug 2016) | 1 line

GH12578 - incremental progress in cleaning up animal organ and plant organ development split

changes in entailments

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r35098 | tberardi | 2016-08-24 09:50:47 -0700 (Wed, 24 Aug 2016) | 1 line

GH12610 NTR component term: heteroreceptor complex - closed

changes in entailments

------------------------------------------------------------------------
r35096 | termgenie | 2016-08-24 08:53:19 -0700 (Wed, 24 Aug 2016) | 3 lines

TermGenie commit for user: sl reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35096)
+++ go_inferences.obo	(working copy)
@@ -73607,13 +73607,13 @@
 [Term]
 id: GO:1902168 ! response to catechin
 is_a: GO:0080184 {is_inferred="true"} ! response to phenylpropanoid
-is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
+is_a: GO:1905395 {is_inferred="true"} ! response to flavonoid
 
 [Term]
 id: GO:1902169 ! cellular response to catechin
 is_a: GO:0071407 {is_inferred="true"} ! cellular response to organic cyclic compound
-is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
 is_a: GO:1902168 {is_inferred="true"} ! response to catechin
+is_a: GO:1905396 {is_inferred="true"} ! cellular response to flavonoid
 
 [Term]
 id: GO:1902170 ! cellular response to reactive nitrogen species
@@ -88461,13 +88461,12 @@
 
 [Term]
 id: GO:1905235 ! response to quercetin
-is_a: GO:0010033 {is_inferred="true"} ! response to organic substance
-is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
+is_a: GO:1905395 {is_inferred="true"} ! response to flavonoid
 
 [Term]
 id: GO:1905236 ! cellular response to quercetin
-is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
 is_a: GO:1905235 {is_inferred="true"} ! response to quercetin
+is_a: GO:1905396 {is_inferred="true"} ! cellular response to flavonoid
 
 [Term]
 id: GO:1905237 ! response to cyclosporin A
@@ -89227,6 +89226,20 @@
 is_a: GO:0048646 {is_inferred="true"} ! anatomical structure formation involved in morphogenesis
 
 [Term]
+id: GO:1905394 ! retromer complex binding
+is_a: GO:0032403 {is_inferred="true"} ! protein complex binding
+
+[Term]
+id: GO:1905395 ! response to flavonoid
+is_a: GO:0010033 {is_inferred="true"} ! response to organic substance
+is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
+
+[Term]
+id: GO:1905396 ! cellular response to flavonoid
+is_a: GO:1901701 {is_inferred="true"} ! cellular response to oxygen-containing compound
+is_a: GO:1905395 {is_inferred="true"} ! response to flavonoid
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35093 | mcourtot | 2016-08-24 07:49:21 -0700 (Wed, 24 Aug 2016) | 1 line

closes https://github.com/geneontology/go-ontology/issues/12592

changes in entailments

------------------------------------------------------------------------
r35091 | dph | 2016-08-24 06:46:36 -0700 (Wed, 24 Aug 2016) | 2 lines

Added mitotic cohesin unloading.

changes in entailments

------------------------------------------------------------------------
r35084 | termgenie | 2016-08-23 17:31:51 -0700 (Tue, 23 Aug 2016) | 3 lines

TermGenie commit for user: tb reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35084)
+++ go_inferences.obo	(working copy)
@@ -11103,6 +11103,10 @@
 is_a: GO:0009962 {is_inferred="true"} ! regulation of flavonoid biosynthetic process
 
 [Term]
+id: GO:0009965 ! leaf morphogenesis
+is_a: GO:1905392 {is_inferred="true"} ! plant organ morphogenesis
+
+[Term]
 id: GO:0009966 ! regulation of signal transduction
 is_a: GO:0010646 {is_inferred="true"} ! regulation of cell communication
 is_a: GO:0023051 {is_inferred="true"} ! regulation of signaling
@@ -11186,6 +11190,10 @@
 is_a: GO:0097159 {is_inferred="true"} ! organic cyclic compound binding
 
 [Term]
+id: GO:0010015 ! root morphogenesis
+is_a: GO:1905392 {is_inferred="true"} ! plant organ morphogenesis
+
+[Term]
 id: GO:0010021 ! amylopectin biosynthetic process
 is_a: GO:0009059 {is_inferred="true"} ! macromolecule biosynthetic process
 is_a: GO:1901137 {is_inferred="true"} ! carbohydrate derivative biosynthetic process
@@ -11752,7 +11760,7 @@
 [Term]
 id: GO:0010311 ! lateral root formation
 is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
-is_a: GO:0048646 {is_inferred="true"} ! anatomical structure formation involved in morphogenesis
+is_a: GO:1905393 {is_inferred="true"} ! plant organ formation
 
 [Term]
 id: GO:0010314 ! phosphatidylinositol-5-phosphate binding
@@ -11796,7 +11804,7 @@
 
 [Term]
 id: GO:0010338 ! leaf formation
-is_a: GO:0048646 {is_inferred="true"} ! anatomical structure formation involved in morphogenesis
+is_a: GO:1905393 {is_inferred="true"} ! plant organ formation
 
 [Term]
 id: GO:0010344 ! seed oilbody biogenesis
@@ -11807,6 +11815,10 @@
 is_a: GO:0009699 {is_inferred="true"} ! phenylpropanoid biosynthetic process
 
 [Term]
+id: GO:0010346 ! shoot axis formation
+is_a: GO:1905393 {is_inferred="true"} ! plant organ formation
+
+[Term]
 id: GO:0010351 ! lithium ion transport
 is_a: GO:0015672 {is_inferred="true"} ! monovalent inorganic cation transport
 is_a: GO:0030001 {is_inferred="true"} ! metal ion transport
@@ -11966,6 +11978,14 @@
 is_a: GO:0021700 {is_inferred="true"} ! developmental maturation
 
 [Term]
+id: GO:0010433 ! bract morphogenesis
+is_a: GO:1905392 {is_inferred="true"} ! plant organ morphogenesis
+
+[Term]
+id: GO:0010434 ! bract formation
+is_a: GO:1905393 {is_inferred="true"} ! plant organ formation
+
+[Term]
 id: GO:0010439 ! regulation of glucosinolate biosynthetic process
 is_a: GO:0031326 {is_inferred="true"} ! regulation of cellular biosynthetic process
 is_a: GO:0042762 {is_inferred="true"} ! regulation of sulfur metabolic process
@@ -42766,10 +42786,11 @@
 [Term]
 id: GO:0048444 ! floral organ morphogenesis
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:1905392 {is_inferred="true"} ! plant organ morphogenesis
 
 [Term]
 id: GO:0048449 ! floral organ formation
-is_a: GO:0048646 {is_inferred="true"} ! anatomical structure formation involved in morphogenesis
+is_a: GO:1905393 {is_inferred="true"} ! plant organ formation
 
 [Term]
 id: GO:0048450 ! floral organ structural organization
@@ -42819,6 +42840,7 @@
 [Term]
 id: GO:0048482 ! plant ovule morphogenesis
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:1905392 {is_inferred="true"} ! plant organ morphogenesis
 
 [Term]
 id: GO:0048488 ! synaptic vesicle endocytosis
@@ -89197,6 +89219,14 @@
 is_a: GO:1901900 {is_inferred="true"} ! regulation of protein localization to cell division site
 
 [Term]
+id: GO:1905392 ! plant organ morphogenesis
+is_a: GO:0009653 {is_inferred="true"} ! anatomical structure morphogenesis
+
+[Term]
+id: GO:1905393 ! plant organ formation
+is_a: GO:0048646 {is_inferred="true"} ! anatomical structure formation involved in morphogenesis
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35082 | tberardi | 2016-08-23 15:41:33 -0700 (Tue, 23 Aug 2016) | 1 line

GH12490 obsolete terms (non existent process) under histone acetylation - closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35082)
+++ go_inferences.obo	(working copy)
@@ -62256,19 +62256,6 @@
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
 
 [Term]
-id: GO:0100029 ! regulation of histone modification by transcription from RNA polymerase II promoter
-is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-
-[Term]
-id: GO:0100030 ! regulation of histone acetylation by transcription from RNA polymerase II promoter
-is_a: GO:0100029 {is_inferred="true"} ! regulation of histone modification by transcription from RNA polymerase II promoter
-
-[Term]
-id: GO:0100031 ! regulation of histone methylation by transcription from RNA polymerase II promoter
-is_a: GO:0100029 {is_inferred="true"} ! regulation of histone modification by transcription from RNA polymerase II promoter
-
-[Term]
 id: GO:0100032 ! positive regulation of phospholipid biosynthetic process by transcription from RNA polymerase II promoter
 is_a: GO:0006366 {is_inferred="true"} ! transcription from RNA polymerase II promoter
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
@@ -64496,20 +64483,6 @@
 is_a: GO:1902884 {is_inferred="true"} ! positive regulation of response to oxidative stress
 
 [Term]
-id: GO:1900410 ! regulation of histone modification by regulation of transcription from RNA polymerase II promoter
-is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
-
-[Term]
-id: GO:1900411 ! regulation of histone acetylation by regulation of transcription from RNA polymerase II promoter
-is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
-is_a: GO:0035065 {is_inferred="true"} ! regulation of histone acetylation
-
-[Term]
-id: GO:1900412 ! regulation of histone methylation by regulation of transcription from RNA polymerase II promoter
-is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
-is_a: GO:0031060 {is_inferred="true"} ! regulation of histone methylation
-
-[Term]
 id: GO:1900413 ! positive regulation of phospholipid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter
 is_a: GO:0045944 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter
 is_a: GO:0071073 {is_inferred="true"} ! positive regulation of phospholipid biosynthetic process
------------------------------------------------------------------------
r35080 | dph | 2016-08-23 10:23:31 -0700 (Tue, 23 Aug 2016) | 2 lines

GH12607-closed and added logical definition for establishment of mitotic sister chromatid cohesion.

changes in entailments

------------------------------------------------------------------------
r35078 | paola | 2016-08-23 08:45:25 -0700 (Tue, 23 Aug 2016) | 3 lines

GH NTR: disordered protein domain specific binding #12585 - work in progress - added GO:0097718 disordered domain specific binding

changes in entailments

------------------------------------------------------------------------
r35076 | mcourtot | 2016-08-23 07:50:57 -0700 (Tue, 23 Aug 2016) | 1 line

updated definition of GO:0008390, testosterone 16-alpha-hydroxylase activity and GO:0101020, estrogen 16-alpha-hydroxylase activity to indicate that product of reaction is 16-alpha-hydroxyestrogen and not 6-alpha-hydroxyestrogen

changes in entailments

------------------------------------------------------------------------
r35071 | paola | 2016-08-23 06:40:45 -0700 (Tue, 23 Aug 2016) | 7 lines

GH NTRs: response to viscosity + copper ion transport across BBB/BCB #12594 - closed - added:

changes in entailments

------------------------------------------------------------------------
r35065 | mcourtot | 2016-08-23 03:44:14 -0700 (Tue, 23 Aug 2016) | 1 line

added id: GO:0101021, name: estrogen 2-hydroxylase activity. Closes #12601

changes in entailments

------------------------------------------------------------------------
r35063 | paola | 2016-08-23 03:21:44 -0700 (Tue, 23 Aug 2016) | 3 lines

GH ntr: dolichol-phosphate-mannose synthase regulator activity #12599 - closed - added GO:0097713 dolichol-phosphate-mannose synthase regulator activity

changes in entailments

------------------------------------------------------------------------
r35058 | termgenie | 2016-08-22 16:12:50 -0700 (Mon, 22 Aug 2016) | 2 lines

TermGenie commit for user: vw reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35058)
+++ go_inferences.obo	(working copy)
@@ -89220,6 +89220,10 @@
 is_a: GO:1905389 {is_inferred="true"} ! response to leukotriene B4
 
 [Term]
+id: GO:1905391 ! regulation of protein localization to cell division site involved in cell separation after cytokinesis
+is_a: GO:1901900 {is_inferred="true"} ! regulation of protein localization to cell division site
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35054 | mcourtot | 2016-08-22 05:33:21 -0700 (Mon, 22 Aug 2016) | 1 line

added GOC:BHF for id: GO:0101020, name: estrogen 16-alpha-hydroxylase activity as per https://github.com/geneontology/go-ontology/issues/12576

changes in entailments

------------------------------------------------------------------------
r35048 | termgenie | 2016-08-22 01:33:03 -0700 (Mon, 22 Aug 2016) | 2 lines

TermGenie commit for user: vw reviewed by pr

changes in entailments

------------------------------------------------------------------------
r35045 | termgenie | 2016-08-21 23:47:27 -0700 (Sun, 21 Aug 2016) | 3 lines

TermGenie commit for user: sl reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35046)
+++ go_inferences.obo	(working copy)
@@ -89202,6 +89202,24 @@
 is_a: GO:1905384 {is_inferred="true"} ! regulation of protein localization to presynapse
 
 [Term]
+id: GO:1905387 ! response to beta-carotene
+is_a: GO:0033993 {is_inferred="true"} ! response to lipid
+
+[Term]
+id: GO:1905388 ! cellular response to beta-carotene
+is_a: GO:0071396 {is_inferred="true"} ! cellular response to lipid
+is_a: GO:1905387 {is_inferred="true"} ! response to beta-carotene
+
+[Term]
+id: GO:1905389 ! response to leukotriene B4
+is_a: GO:0070542 {is_inferred="true"} ! response to fatty acid
+
+[Term]
+id: GO:1905390 ! cellular response to leukotriene B4
+is_a: GO:0071398 {is_inferred="true"} ! cellular response to fatty acid
+is_a: GO:1905389 {is_inferred="true"} ! response to leukotriene B4
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r35043 | termgenie | 2016-08-21 23:40:20 -0700 (Sun, 21 Aug 2016) | 2 lines

TermGenie commit for user: sl reviewed by pr

changes in entailments

------------------------------------------------------------------------
r35009 | dph | 2016-08-19 12:19:19 -0700 (Fri, 19 Aug 2016) | 2 lines

Tweaked the definition of GO:0004467 to make the core definition consistent with the name of the activity and the gloss of the definition. GH12568-closed.

changes in entailments

------------------------------------------------------------------------
r35007 | dph | 2016-08-19 10:02:18 -0700 (Fri, 19 Aug 2016) | 2 lines

Fixed the definition of GO:0004654 as described in GH12516. GH12516-closed.

changes in entailments

------------------------------------------------------------------------
r34999 | termgenie | 2016-08-18 09:26:29 -0700 (Thu, 18 Aug 2016) | 2 lines

TermGenie commit for user: bhm reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 35000)
+++ go_inferences.obo	(working copy)
@@ -89166,6 +89166,10 @@
 is_a: GO:1905377 {is_inferred="true"} ! response to D-galactose
 
 [Term]
+id: GO:1905379 ! beta-N-acetylhexosaminidase complex
+is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
+
+[Term]
 id: GO:1905380 ! regulation of snRNA transcription from RNA polymerase II promoter
 is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
 
------------------------------------------------------------------------
r34998 | termgenie | 2016-08-18 09:20:14 -0700 (Thu, 18 Aug 2016) | 4 lines

TermGenie commit for user: bhm reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34998)
+++ go_inferences.obo	(working copy)
@@ -89166,6 +89166,20 @@
 is_a: GO:1905377 {is_inferred="true"} ! response to D-galactose
 
 [Term]
+id: GO:1905380 ! regulation of snRNA transcription from RNA polymerase II promoter
+is_a: GO:0006357 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter
+
+[Term]
+id: GO:1905381 ! negative regulation of snRNA transcription from RNA polymerase II promoter
+is_a: GO:0000122 {is_inferred="true"} ! negative regulation of transcription from RNA polymerase II promoter
+is_a: GO:1905380 {is_inferred="true"} ! regulation of snRNA transcription from RNA polymerase II promoter
+
+[Term]
+id: GO:1905382 ! positive regulation of snRNA transcription from RNA polymerase II promoter
+is_a: GO:0045944 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter
+is_a: GO:1905380 {is_inferred="true"} ! regulation of snRNA transcription from RNA polymerase II promoter
+
+[Term]
 id: GO:1905383 ! protein localization to presynapse
 is_a: GO:0035418 {is_inferred="true"} ! protein localization to synapse
 
------------------------------------------------------------------------
r34996 | termgenie | 2016-08-18 08:44:36 -0700 (Thu, 18 Aug 2016) | 3 lines

TermGenie commit for user: sl reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34996)
+++ go_inferences.obo	(working copy)
@@ -89157,6 +89157,15 @@
 is_a: GO:1904959 {is_inferred="true"} ! regulation of cytochrome-c oxidase activity
 
 [Term]
+id: GO:1905377 ! response to D-galactose
+is_a: GO:0009746 {is_inferred="true"} ! response to hexose
+
+[Term]
+id: GO:1905378 ! cellular response to D-galactose
+is_a: GO:0071331 {is_inferred="true"} ! cellular response to hexose stimulus
+is_a: GO:1905377 {is_inferred="true"} ! response to D-galactose
+
+[Term]
 id: GO:1905383 ! protein localization to presynapse
 is_a: GO:0035418 {is_inferred="true"} ! protein localization to synapse
 
------------------------------------------------------------------------
r34993 | termgenie | 2016-08-18 08:22:38 -0700 (Thu, 18 Aug 2016) | 2 lines

TermGenie commit for user: sl reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34994)
+++ go_inferences.obo	(working copy)
@@ -89149,6 +89149,14 @@
 is_a: GO:1905374 {is_inferred="true"} ! response to homocysteine
 
 [Term]
+id: GO:1905376 ! negative regulation of cytochrome-c oxidase activity
+is_a: GO:0032413 {is_inferred="true"} ! negative regulation of ion transmembrane transporter activity
+is_a: GO:0051354 {is_inferred="true"} ! negative regulation of oxidoreductase activity
+is_a: GO:1904063 {is_inferred="true"} ! negative regulation of cation transmembrane transport
+is_a: GO:1904733 {is_inferred="true"} ! negative regulation of electron carrier activity
+is_a: GO:1904959 {is_inferred="true"} ! regulation of cytochrome-c oxidase activity
+
+[Term]
 id: GO:1905383 ! protein localization to presynapse
 is_a: GO:0035418 {is_inferred="true"} ! protein localization to synapse
 
------------------------------------------------------------------------
r34991 | termgenie | 2016-08-18 08:16:11 -0700 (Thu, 18 Aug 2016) | 3 lines

TermGenie commit for user: sl reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34992)
+++ go_inferences.obo	(working copy)
@@ -89140,6 +89140,15 @@
 is_a: GO:1905371 {is_inferred="true"} ! ceramide phosphoethanolamine metabolic process
 
 [Term]
+id: GO:1905374 ! response to homocysteine
+is_a: GO:0043200 {is_inferred="true"} ! response to amino acid
+
+[Term]
+id: GO:1905375 ! cellular response to homocysteine
+is_a: GO:0071230 {is_inferred="true"} ! cellular response to amino acid stimulus
+is_a: GO:1905374 {is_inferred="true"} ! response to homocysteine
+
+[Term]
 id: GO:1905383 ! protein localization to presynapse
 is_a: GO:0035418 {is_inferred="true"} ! protein localization to synapse
 
------------------------------------------------------------------------
r34990 | termgenie | 2016-08-18 08:12:45 -0700 (Thu, 18 Aug 2016) | 4 lines

TermGenie commit for user: dos reviewed by dos

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34990)
+++ go_inferences.obo	(working copy)
@@ -89144,6 +89144,20 @@
 is_a: GO:0035418 {is_inferred="true"} ! protein localization to synapse
 
 [Term]
+id: GO:1905384 ! regulation of protein localization to presynapse
+is_a: GO:1902473 {is_inferred="true"} ! regulation of protein localization to synapse
+
+[Term]
+id: GO:1905385 ! negative regulation of protein localization to presynapse
+is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
+is_a: GO:1905384 {is_inferred="true"} ! regulation of protein localization to presynapse
+
+[Term]
+id: GO:1905386 ! positive regulation of protein localization to presynapse
+is_a: GO:1902474 {is_inferred="true"} ! positive regulation of protein localization to synapse
+is_a: GO:1905384 {is_inferred="true"} ! regulation of protein localization to presynapse
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34988 | davidos | 2016-08-18 08:05:13 -0700 (Thu, 18 Aug 2016) | 1 line

presynaptic assembly terms #12220 + NTR: ASC-1 complex #12460

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34988)
+++ go_inferences.obo	(working copy)
@@ -8597,6 +8597,7 @@
 [Term]
 id: GO:0007416 ! synapse assembly
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
+is_a: GO:0050808 {is_inferred="true"} ! synapse organization
 
 [Term]
 id: GO:0007444 ! imaginal disc development
@@ -59663,11 +59664,13 @@
 
 [Term]
 id: GO:0097104 ! postsynaptic membrane assembly
+is_a: GO:0001941 {is_inferred="true"} ! postsynaptic membrane organization
 is_a: GO:0071709 {is_inferred="true"} ! membrane assembly
 
 [Term]
 id: GO:0097105 ! presynaptic membrane assembly
 is_a: GO:0071709 {is_inferred="true"} ! membrane assembly
+is_a: GO:0097090 {is_inferred="true"} ! presynaptic membrane organization
 
 [Term]
 id: GO:0097106 ! postsynaptic density organization
@@ -59676,6 +59679,7 @@
 [Term]
 id: GO:0097107 ! postsynaptic density assembly
 is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
+is_a: GO:0097106 {is_inferred="true"} ! postsynaptic density organization
 
 [Term]
 id: GO:0097120 ! receptor localization to synapse
@@ -61680,6 +61684,10 @@
 is_a: GO:0099051 {is_inferred="true"} ! vesicle scission involved in endocytosis
 
 [Term]
+id: GO:0099054 ! presynapse assembly
+is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
+
+[Term]
 id: GO:0099055 ! integral component of postsynaptic membrane
 is_a: GO:0005887 {is_inferred="true"} ! integral component of plasma membrane
 is_a: GO:0098936 {is_inferred="true"} ! intrinsic component of postsynaptic membrane
@@ -61748,6 +61756,10 @@
 is_a: GO:0098955 {is_inferred="true"} ! intrinsic component of presynaptic endosome membrane
 
 [Term]
+id: GO:0099068 ! postsynapse assembly
+is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
+
+[Term]
 id: GO:0099400 ! caveola neck
 is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
 
------------------------------------------------------------------------
r34986 | termgenie | 2016-08-18 07:46:50 -0700 (Thu, 18 Aug 2016) | 2 lines

TermGenie commit for user: dos reviewed by dos

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34986)
+++ go_inferences.obo	(working copy)
@@ -62078,8 +62078,8 @@
 [Term]
 id: GO:0099641 ! anterograde axonal protein transport
 is_a: GO:0008089 {is_inferred="true"} ! anterograde axonal transport
-is_a: GO:0035418 {is_inferred="true"} ! protein localization to synapse
 is_a: GO:0099640 {is_inferred="true"} ! axo-dendritic protein transport
+is_a: GO:1905383 {is_inferred="true"} ! protein localization to presynapse
 
 [Term]
 id: GO:0099642 ! retrograde axonal protein transport
@@ -62088,8 +62088,8 @@
 
 [Term]
 id: GO:0099644 ! protein localization to presynaptic membrane
-is_a: GO:0035418 {is_inferred="true"} ! protein localization to synapse
 is_a: GO:0072657 {is_inferred="true"} ! protein localization to membrane
+is_a: GO:1905383 {is_inferred="true"} ! protein localization to presynapse
 is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
 
 [Term]
@@ -89128,6 +89128,10 @@
 is_a: GO:1905371 {is_inferred="true"} ! ceramide phosphoethanolamine metabolic process
 
 [Term]
+id: GO:1905383 ! protein localization to presynapse
+is_a: GO:0035418 {is_inferred="true"} ! protein localization to synapse
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34980 | termgenie | 2016-08-18 07:37:16 -0700 (Thu, 18 Aug 2016) | 2 lines

TermGenie commit for user: bhm reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34983)
+++ go_inferences.obo	(working copy)
@@ -8893,6 +8893,10 @@
 is_a: GO:0022414 {is_inferred="true"} ! reproductive process
 
 [Term]
+id: GO:0008303 ! caspase complex
+is_a: GO:1905369 {is_inferred="true"} ! endopeptidase complex
+
+[Term]
 id: GO:0008305 ! integrin complex
 is_a: GO:0098636 {is_inferred="true"} ! protein complex involved in cell adhesion
 is_a: GO:0098802 {is_inferred="true"} ! plasma membrane receptor complex
@@ -50988,7 +50992,7 @@
 
 [Term]
 id: GO:0061672 ! glutathione hydrolase complex
-is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
+is_a: GO:1905368 {is_inferred="true"} ! peptidase complex
 
 [Term]
 id: GO:0061678 ! Entner-Doudoroff pathway
@@ -88687,7 +88691,7 @@
 
 [Term]
 id: GO:1905286 ! serine-type peptidase complex
-is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
+is_a: GO:1905368 {is_inferred="true"} ! peptidase complex
 
 [Term]
 id: GO:1905287 ! positive regulation of G2/M transition of mitotic cell cycle involved in cellular response to nitrogen starvation
@@ -89094,6 +89098,19 @@
 is_a: GO:1905365 {is_inferred="true"} ! regulation of intralumenal vesicle formation
 
 [Term]
+id: GO:1905368 ! peptidase complex
+is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
+
+[Term]
+id: GO:1905369 ! endopeptidase complex
+is_a: GO:1905368 {is_inferred="true"} ! peptidase complex
+
+[Term]
+id: GO:1905370 ! serine-type endopeptidase complex
+is_a: GO:1905286 {is_inferred="true"} ! serine-type peptidase complex
+is_a: GO:1905369 {is_inferred="true"} ! endopeptidase complex
+
+[Term]
 id: GO:1905371 ! ceramide phosphoethanolamine metabolic process
 is_a: GO:0006644 {is_inferred="true"} ! phospholipid metabolic process
 is_a: GO:0006665 {is_inferred="true"} ! sphingolipid metabolic process
@@ -89984,7 +90001,7 @@
 [Term]
 id: GO:1990850 ! H-gal-GP complex
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
-is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
+is_a: GO:1905368 {is_inferred="true"} ! peptidase complex
 
 [Term]
 id: GO:1990851 ! Wnt-Frizzled-LRP5/6 complex
------------------------------------------------------------------------
r34975 | termgenie | 2016-08-18 07:03:48 -0700 (Thu, 18 Aug 2016) | 4 lines

TermGenie commit for user: bc reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34976)
+++ go_inferences.obo	(working copy)
@@ -89077,6 +89077,23 @@
 is_a: GO:0031338 {is_inferred="true"} ! regulation of vesicle fusion
 
 [Term]
+id: GO:1905365 ! regulation of intralumenal vesicle formation
+is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
+is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
+
+[Term]
+id: GO:1905366 ! negative regulation of intralumenal vesicle formation
+is_a: GO:0010639 {is_inferred="true"} ! negative regulation of organelle organization
+is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
+is_a: GO:1905365 {is_inferred="true"} ! regulation of intralumenal vesicle formation
+
+[Term]
+id: GO:1905367 ! positive regulation of intralumenal vesicle formation
+is_a: GO:0010638 {is_inferred="true"} ! positive regulation of organelle organization
+is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
+is_a: GO:1905365 {is_inferred="true"} ! regulation of intralumenal vesicle formation
+
+[Term]
 id: GO:1905371 ! ceramide phosphoethanolamine metabolic process
 is_a: GO:0006644 {is_inferred="true"} ! phospholipid metabolic process
 is_a: GO:0006665 {is_inferred="true"} ! sphingolipid metabolic process
------------------------------------------------------------------------
r34974 | termgenie | 2016-08-18 06:58:34 -0700 (Thu, 18 Aug 2016) | 2 lines

TermGenie commit for user: bc reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34974)
+++ go_inferences.obo	(working copy)
@@ -89063,6 +89063,20 @@
 is_a: GO:0005215 {is_inferred="true"} ! transporter activity
 
 [Term]
+id: GO:1905362 ! negative regulation of endosomal vesicle fusion
+is_a: GO:0031339 {is_inferred="true"} ! negative regulation of vesicle fusion
+is_a: GO:1905364 {is_inferred="true"} ! regulation of endosomal vesicle fusion
+
+[Term]
+id: GO:1905363 ! positive regulation of endosomal vesicle fusion
+is_a: GO:0031340 {is_inferred="true"} ! positive regulation of vesicle fusion
+is_a: GO:1905364 {is_inferred="true"} ! regulation of endosomal vesicle fusion
+
+[Term]
+id: GO:1905364 ! regulation of endosomal vesicle fusion
+is_a: GO:0031338 {is_inferred="true"} ! regulation of vesicle fusion
+
+[Term]
 id: GO:1905371 ! ceramide phosphoethanolamine metabolic process
 is_a: GO:0006644 {is_inferred="true"} ! phospholipid metabolic process
 is_a: GO:0006665 {is_inferred="true"} ! sphingolipid metabolic process
------------------------------------------------------------------------
r34971 | mcourtot | 2016-08-18 05:26:47 -0700 (Thu, 18 Aug 2016) | 1 line

removed goslim_pombe on GO:0098974 postsynaptic actin cytoskeleton organization as per https://github.com/geneontology/go-ontology/issues/12467

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34971)
+++ go_inferences.obo	(working copy)
@@ -89064,16 +89064,19 @@
 
 [Term]
 id: GO:1905371 ! ceramide phosphoethanolamine metabolic process
-is_a: GO:0008152 {is_inferred="true"} ! metabolic process
+is_a: GO:0006644 {is_inferred="true"} ! phospholipid metabolic process
+is_a: GO:0006665 {is_inferred="true"} ! sphingolipid metabolic process
 
 [Term]
 id: GO:1905372 ! ceramide phosphoethanolamine catabolic process
-is_a: GO:0009056 {is_inferred="true"} ! catabolic process
+is_a: GO:0009395 {is_inferred="true"} ! phospholipid catabolic process
+is_a: GO:0030149 {is_inferred="true"} ! sphingolipid catabolic process
 is_a: GO:1905371 {is_inferred="true"} ! ceramide phosphoethanolamine metabolic process
 
 [Term]
 id: GO:1905373 ! ceramide phosphoethanolamine biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0008654 {is_inferred="true"} ! phospholipid biosynthetic process
+is_a: GO:0030148 {is_inferred="true"} ! sphingolipid biosynthetic process
 is_a: GO:1905371 {is_inferred="true"} ! ceramide phosphoethanolamine metabolic process
 
 [Term]
------------------------------------------------------------------------
r34960 | termgenie | 2016-08-16 11:36:23 -0700 (Tue, 16 Aug 2016) | 4 lines

TermGenie commit for user: hjd reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34960)
+++ go_inferences.obo	(working copy)
@@ -89063,6 +89063,20 @@
 is_a: GO:0005215 {is_inferred="true"} ! transporter activity
 
 [Term]
+id: GO:1905371 ! ceramide phosphoethanolamine metabolic process
+is_a: GO:0008152 {is_inferred="true"} ! metabolic process
+
+[Term]
+id: GO:1905372 ! ceramide phosphoethanolamine catabolic process
+is_a: GO:0009056 {is_inferred="true"} ! catabolic process
+is_a: GO:1905371 {is_inferred="true"} ! ceramide phosphoethanolamine metabolic process
+
+[Term]
+id: GO:1905373 ! ceramide phosphoethanolamine biosynthetic process
+is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:1905371 {is_inferred="true"} ! ceramide phosphoethanolamine metabolic process
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34958 | hjd | 2016-08-16 10:46:55 -0700 (Tue, 16 Aug 2016) | 2 lines

added term for LI Ni: GO:0002950

changes in entailments

------------------------------------------------------------------------
r34954 | dph | 2016-08-16 04:59:09 -0700 (Tue, 16 Aug 2016) | 2 lines

Removed taxon constraint for regulation of cell migration.

changes in entailments

------------------------------------------------------------------------
r34932 | termgenie | 2016-08-15 01:19:41 -0700 (Mon, 15 Aug 2016) | 2 lines

TermGenie commit for user: pde reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34932)
+++ go_inferences.obo	(working copy)
@@ -14703,6 +14703,7 @@
 id: GO:0015194 ! L-serine transmembrane transporter activity
 is_a: GO:0015179 {is_inferred="true"} ! L-amino acid transmembrane transporter activity
 is_a: GO:0022889 {is_inferred="true"} ! serine transmembrane transporter activity
+is_a: GO:1905361 {is_inferred="true"} ! L-serine transporter activity
 
 [Term]
 id: GO:0015195 ! L-threonine transmembrane transporter activity
@@ -89058,6 +89059,10 @@
 is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
 
 [Term]
+id: GO:1905361 ! L-serine transporter activity
+is_a: GO:0005215 {is_inferred="true"} ! transporter activity
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34885 | termgenie | 2016-08-12 02:05:50 -0700 (Fri, 12 Aug 2016) | 2 lines

TermGenie commit for user: bhm reviewed by mec

changes in entailments

------------------------------------------------------------------------
r34885 | termgenie | 2016-08-12 02:05:50 -0700 (Fri, 12 Aug 2016) | 2 lines

TermGenie commit for user: bhm reviewed by mec

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34888)
+++ go_inferences.obo	(working copy)
@@ -5347,7 +5347,7 @@
 id: GO:0005834 ! heterotrimeric G-protein complex
 is_a: GO:0044424 {is_inferred="true"} ! intracellular part
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
-is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
+is_a: GO:1905360 {is_inferred="true"} ! GTPase complex
 
 [Term]
 id: GO:0005836 ! fatty-acyl-CoA synthase complex
@@ -89054,6 +89054,10 @@
 is_a: GO:0072698 {is_inferred="true"} ! protein localization to microtubule cytoskeleton
 
 [Term]
+id: GO:1905360 ! GTPase complex
+is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34866 | mcourtot | 2016-08-11 07:25:00 -0700 (Thu, 11 Aug 2016) | 1 line

modified ILR20 and ILR28 as per https://github.com/geneontology/go-ontology/issues/12375, and created NTR estrogen 16-alpha-hydroxylase activity as per https://github.com/geneontology/go-ontology/issues/12576

changes in entailments

------------------------------------------------------------------------
r34862 | termgenie | 2016-08-11 02:54:15 -0700 (Thu, 11 Aug 2016) | 2 lines

TermGenie commit for user: mah reviewed by mec

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34862)
+++ go_inferences.obo	(working copy)
@@ -74912,7 +74912,7 @@
 [Term]
 id: GO:1902441 ! protein localization to meiotic spindle pole body
 is_a: GO:0022414 {is_inferred="true"} ! reproductive process
-is_a: GO:0072698 {is_inferred="true"} ! protein localization to microtubule cytoskeleton
+is_a: GO:1905359 {is_inferred="true"} ! protein localization to meiotic spindle
 
 [Term]
 id: GO:1902442 ! regulation of ripoptosome assembly involved in necroptotic process
@@ -78028,7 +78028,7 @@
 
 [Term]
 id: GO:1903096 ! protein localization to meiotic spindle midzone
-is_a: GO:0072698 {is_inferred="true"} ! protein localization to microtubule cytoskeleton
+is_a: GO:1905359 {is_inferred="true"} ! protein localization to meiotic spindle
 
 [Term]
 id: GO:1903097 ! regulation of CENP-A containing nucleosome assembly
@@ -89050,6 +89050,10 @@
 is_a: GO:1905356 {is_inferred="true"} ! regulation of snRNA pseudouridine synthesis
 
 [Term]
+id: GO:1905359 ! protein localization to meiotic spindle
+is_a: GO:0072698 {is_inferred="true"} ! protein localization to microtubule cytoskeleton
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34859 | dph | 2016-08-10 09:01:09 -0700 (Wed, 10 Aug 2016) | 2 lines

Added part of relation between substrate localization to autophagosome and autophagosome assembly.

changes in entailments

------------------------------------------------------------------------
r34854 | paola | 2016-08-10 06:12:45 -0700 (Wed, 10 Aug 2016) | 3 lines

Stemming from GH 'cilium morphogenesis' and 'cilium assembly' #12236:

changes in entailments

------------------------------------------------------------------------
r34848 | paola | 2016-08-10 03:35:19 -0700 (Wed, 10 Aug 2016) | 3 lines

GH 'cilium morphogenesis' and 'cilium assembly' #12236 - work in progress - added GOC:cilia and PMID:27350441 as a dbxref to ‘cilium assembly’ and ‘cilium disassembly’.

changes in entailments

------------------------------------------------------------------------
r34846 | termgenie | 2016-08-10 01:45:13 -0700 (Wed, 10 Aug 2016) | 4 lines

TermGenie commit for user: se reviewed by mec

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34846)
+++ go_inferences.obo	(working copy)
@@ -89032,6 +89032,24 @@
 is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
 
 [Term]
+id: GO:1905355 ! spine apparatus assembly
+is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
+
+[Term]
+id: GO:1905356 ! regulation of snRNA pseudouridine synthesis
+is_a: GO:0051252 {is_inferred="true"} ! regulation of RNA metabolic process
+
+[Term]
+id: GO:1905357 ! negative regulation of snRNA pseudouridine synthesis
+is_a: GO:0051253 {is_inferred="true"} ! negative regulation of RNA metabolic process
+is_a: GO:1905356 {is_inferred="true"} ! regulation of snRNA pseudouridine synthesis
+
+[Term]
+id: GO:1905358 ! positive regulation of snRNA pseudouridine synthesis
+is_a: GO:0051254 {is_inferred="true"} ! positive regulation of RNA metabolic process
+is_a: GO:1905356 {is_inferred="true"} ! regulation of snRNA pseudouridine synthesis
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34836 | paola | 2016-08-09 05:22:13 -0700 (Tue, 09 Aug 2016) | 2 lines

Added to my last edit

changes in entailments

------------------------------------------------------------------------
r34835 | paola | 2016-08-09 05:18:31 -0700 (Tue, 09 Aug 2016) | 3 lines

GH NTR : lipid particle exit from endoplasmic reticulum as a child of intracellular lipid particle transport #12473 - closed - edited def and placement of GO:0035459 cargo loading into vesicle and descendants

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34835)
+++ go_inferences.obo	(working copy)
@@ -69227,13 +69227,12 @@
 [Term]
 id: GO:1901301 ! regulation of cargo loading into COPII-coated vesicle
 is_a: GO:0033043 {is_inferred="true"} ! regulation of organelle organization
-is_a: GO:0043254 {is_inferred="true"} ! regulation of protein complex assembly
+is_a: GO:0044087 {is_inferred="true"} ! regulation of cellular component biogenesis
 is_a: GO:0060628 {is_inferred="true"} ! regulation of ER to Golgi vesicle-mediated transport
 
 [Term]
 id: GO:1901303 ! negative regulation of cargo loading into COPII-coated vesicle
 is_a: GO:0010639 {is_inferred="true"} ! negative regulation of organelle organization
-is_a: GO:0031333 {is_inferred="true"} ! negative regulation of protein complex assembly
 is_a: GO:0032387 {is_inferred="true"} ! negative regulation of intracellular transport
 is_a: GO:1901301 {is_inferred="true"} ! regulation of cargo loading into COPII-coated vesicle
 
------------------------------------------------------------------------
r34829 | mcourtot | 2016-08-09 02:49:08 -0700 (Tue, 09 Aug 2016) | 1 line

updated definition IL12R and IL23R as per https://github.com/geneontology/go-ontology/issues/12375

changes in entailments

------------------------------------------------------------------------
r34822 | hjd | 2016-08-08 13:17:56 -0700 (Mon, 08 Aug 2016) | 2 lines

added more plant enzyme mapping function terms

changes in entailments

------------------------------------------------------------------------
r34819 | mcourtot | 2016-08-08 08:05:21 -0700 (Mon, 08 Aug 2016) | 1 line

added part of nucleolus GO:0101019

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34819)
+++ go_inferences.obo	(working copy)
@@ -62436,6 +62436,11 @@
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
 
 [Term]
+id: GO:0101019 ! nucleolar exosome (RNase complex)
+is_a: GO:0000176 {is_inferred="true"} ! nuclear exosome (RNase complex)
+is_a: GO:0044452 {is_inferred="true"} ! nucleolar part
+
+[Term]
 id: GO:1900000 ! regulation of anthocyanin catabolic process
 is_a: GO:0009894 {is_inferred="true"} ! regulation of catabolic process
 is_a: GO:0031537 {is_inferred="true"} ! regulation of anthocyanin metabolic process
------------------------------------------------------------------------
r34816 | mcourtot | 2016-08-08 07:35:38 -0700 (Mon, 08 Aug 2016) | 1 line

removed wrong synonyms GO:0101019

changes in entailments

------------------------------------------------------------------------
r34814 | mcourtot | 2016-08-08 07:13:34 -0700 (Mon, 08 Aug 2016) | 1 line

closes https://github.com/geneontology/go-ontology/issues/12574

changes in entailments

------------------------------------------------------------------------
r34812 | dph | 2016-08-08 05:39:42 -0700 (Mon, 08 Aug 2016) | 2 lines

Tweaked the definition of GO:0031297.

changes in entailments

------------------------------------------------------------------------
r34810 | termgenie | 2016-08-08 05:26:18 -0700 (Mon, 08 Aug 2016) | 2 lines

TermGenie commit for user: rph reviewed by dph

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34810)
+++ go_inferences.obo	(working copy)
@@ -89012,6 +89012,10 @@
 is_a: GO:0006461 {is_inferred="true"} ! protein complex assembly
 
 [Term]
+id: GO:1905351 ! pericyte cell migration
+is_a: GO:0016477 {is_inferred="true"} ! cell migration
+
+[Term]
 id: GO:1905352 ! ciliary necklace assembly
 is_a: GO:0006461 {is_inferred="true"} ! protein complex assembly
 
------------------------------------------------------------------------
r34808 | termgenie | 2016-08-08 05:12:31 -0700 (Mon, 08 Aug 2016) | 2 lines

TermGenie commit for user: bhm reviewed by mec

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34808)
+++ go_inferences.obo	(working copy)
@@ -89020,6 +89020,10 @@
 is_a: GO:0006461 {is_inferred="true"} ! protein complex assembly
 
 [Term]
+id: GO:1905354 ! exoribonuclease complex
+is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34769 | dph | 2016-08-05 12:07:28 -0700 (Fri, 05 Aug 2016) | 2 lines

GH12566-closed.

changes in entailments

------------------------------------------------------------------------
r34767 | dph | 2016-08-05 09:34:30 -0700 (Fri, 05 Aug 2016) | 2 lines

GH12570-closed.

changes in entailments

------------------------------------------------------------------------
r34765 | dph | 2016-08-05 09:27:31 -0700 (Fri, 05 Aug 2016) | 2 lines

GH12571-closed.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34765)
+++ go_inferences.obo	(working copy)
@@ -51112,6 +51112,11 @@
 is_a: GO:0044452 {is_inferred="true"} ! nucleolar part
 
 [Term]
+id: GO:0061779 ! Tapasin-ERp57 complex
+is_a: GO:0044432 {is_inferred="true"} ! endoplasmic reticulum part
+is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
------------------------------------------------------------------------
r34763 | dph | 2016-08-05 08:50:04 -0700 (Fri, 05 Aug 2016) | 2 lines

I added back the relation that 'cellular developmental process' is_a 'single-organism developmental process'.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34763)
+++ go_inferences.obo	(working copy)
@@ -1252,7 +1252,6 @@
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 is_a: GO:0022602 {is_inferred="true"} ! ovulation cycle process
 is_a: GO:0030855 {is_inferred="true"} ! epithelial cell differentiation
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0001550 ! ovarian cumulus expansion
@@ -8426,7 +8425,6 @@
 [Term]
 id: GO:0007278 ! pole cell fate determination
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0007279 ! pole cell formation
@@ -8476,7 +8474,6 @@
 [Term]
 id: GO:0007294 ! germarium-derived oocyte fate determination
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0007295 ! growth of a germarium-derived egg chamber
@@ -8622,7 +8619,6 @@
 [Term]
 id: GO:0007531 ! mating type determination
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0007534 ! gene conversion at mating-type locus
@@ -8631,7 +8627,6 @@
 [Term]
 id: GO:0007535 ! donor selection
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0007543 ! sex determination, somatic-gonadal interaction
@@ -10480,7 +10475,6 @@
 [Term]
 id: GO:0009560 ! embryo sac egg cell differentiation
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0009568 ! amyloplast starch grain
@@ -11137,7 +11131,6 @@
 [Term]
 id: GO:0009994 ! oocyte differentiation
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0009996 ! negative regulation of cell fate specification
@@ -11303,7 +11296,6 @@
 id: GO:0010059 ! positive regulation of atrichoblast fate specification
 is_a: GO:0010058 {is_inferred="true"} ! regulation of atrichoblast fate specification
 is_a: GO:0042660 {is_inferred="true"} ! positive regulation of cell fate specification
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1903890 {is_inferred="true"} ! positive regulation of plant epidermal cell differentiation
 
@@ -11311,7 +11303,6 @@
 id: GO:0010060 ! negative regulation of atrichoblast fate specification
 is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
 is_a: GO:0010058 {is_inferred="true"} ! regulation of atrichoblast fate specification
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1903889 {is_inferred="true"} ! negative regulation of plant epidermal cell differentiation
 
@@ -11325,7 +11316,6 @@
 id: GO:0010062 ! negative regulation of trichoblast fate specification
 is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
 is_a: GO:0010061 {is_inferred="true"} ! regulation of trichoblast fate specification
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1903889 {is_inferred="true"} ! negative regulation of plant epidermal cell differentiation
 
@@ -11333,7 +11323,6 @@
 id: GO:0010063 ! positive regulation of trichoblast fate specification
 is_a: GO:0010061 {is_inferred="true"} ! regulation of trichoblast fate specification
 is_a: GO:0042660 {is_inferred="true"} ! positive regulation of cell fate specification
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1903890 {is_inferred="true"} ! positive regulation of plant epidermal cell differentiation
 
@@ -11604,7 +11593,6 @@
 [Term]
 id: GO:0010198 ! synergid death
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0010200 ! response to chitin
@@ -11640,7 +11628,6 @@
 [Term]
 id: GO:0010234 ! anther wall tapetum cell fate specification
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0010236 ! plastoquinone biosynthetic process
@@ -12044,7 +12031,6 @@
 [Term]
 id: GO:0010480 ! microsporocyte differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 is_a: GO:0048533 {is_inferred="true"} ! sporocyte differentiation
 
 [Term]
@@ -12604,7 +12590,6 @@
 [Term]
 id: GO:0010654 ! apical cell fate commitment
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0010656 ! negative regulation of muscle cell apoptotic process
@@ -12836,12 +12821,10 @@
 
 [Term]
 id: GO:0010720 ! positive regulation of cell development
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
 
 [Term]
 id: GO:0010721 ! negative regulation of cell development
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
 
 [Term]
@@ -20346,7 +20329,6 @@
 
 [Term]
 id: GO:0030220 ! platelet formation
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 is_a: GO:0048646 {is_inferred="true"} ! anatomical structure formation involved in morphogenesis
 
 [Term]
@@ -21249,13 +21231,11 @@
 id: GO:0030857 ! negative regulation of epithelial cell differentiation
 is_a: GO:0030856 {is_inferred="true"} ! regulation of epithelial cell differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 
 [Term]
 id: GO:0030858 ! positive regulation of epithelial cell differentiation
 is_a: GO:0030856 {is_inferred="true"} ! regulation of epithelial cell differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 
 [Term]
 id: GO:0030860 ! regulation of polarized epithelial cell differentiation
@@ -21715,7 +21695,6 @@
 [Term]
 id: GO:0031149 ! sorocarp stalk cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0031152 ! aggregation involved in sorocarp development
@@ -22417,7 +22396,6 @@
 [Term]
 id: GO:0031494 ! regulation of mating type switching
 is_a: GO:0010453 {is_inferred="true"} ! regulation of cell fate commitment
-is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
 is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
 
 [Term]
@@ -22424,7 +22402,6 @@
 id: GO:0031495 ! negative regulation of mating type switching
 is_a: GO:0010454 {is_inferred="true"} ! negative regulation of cell fate commitment
 is_a: GO:0031494 {is_inferred="true"} ! regulation of mating type switching
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
 
 [Term]
@@ -22431,7 +22408,6 @@
 id: GO:0031496 ! positive regulation of mating type switching
 is_a: GO:0010455 {is_inferred="true"} ! positive regulation of cell fate commitment
 is_a: GO:0031494 {is_inferred="true"} ! regulation of mating type switching
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
 
 [Term]
@@ -25883,7 +25859,6 @@
 [Term]
 id: GO:0032989 ! cellular component morphogenesis
 is_a: GO:0009653 {is_inferred="true"} ! anatomical structure morphogenesis
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0032990 ! cell part morphogenesis
@@ -26784,7 +26759,6 @@
 [Term]
 id: GO:0033327 ! Leydig cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0033329 ! kaempferol O-glucoside metabolic process
@@ -29020,7 +28994,6 @@
 [Term]
 id: GO:0035047 ! centrosomal and pronuclear rotation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0035050 ! embryonic heart tube development
@@ -29094,7 +29067,6 @@
 [Term]
 id: GO:0035155 ! negative regulation of terminal cell fate specification, open tracheal system
 is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
 
@@ -29101,7 +29073,6 @@
 [Term]
 id: GO:0035157 ! negative regulation of fusion cell fate specification
 is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
 
@@ -29184,7 +29155,6 @@
 [Term]
 id: GO:0035234 ! ectopic germ cell programmed cell death
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0035238 ! vitamin A biosynthetic process
@@ -32712,7 +32682,6 @@
 id: GO:0042683 ! negative regulation of compound eye cone cell fate specification
 is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
 is_a: GO:0042682 {is_inferred="true"} ! regulation of compound eye cone cell fate specification
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 
 [Term]
@@ -35648,7 +35617,6 @@
 [Term]
 id: GO:0044671 ! sorocarp spore cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0044673 ! 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase complex
@@ -36970,7 +36938,6 @@
 id: GO:0045476 ! nurse cell apoptotic process
 is_a: GO:0010623 {is_inferred="true"} ! programmed cell death involved in cell development
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 is_a: GO:1902742 {is_inferred="true"} ! apoptotic process involved in development
 
 [Term]
@@ -37344,6 +37311,7 @@
 
 [Term]
 id: GO:0045595 ! regulation of cell differentiation
+is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
 is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
 
 [Term]
@@ -37350,11 +37318,13 @@
 id: GO:0045596 ! negative regulation of cell differentiation
 is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
 is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 
 [Term]
 id: GO:0045597 ! positive regulation of cell differentiation
 is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
 is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 
 [Term]
 id: GO:0045598 ! regulation of fat cell differentiation
@@ -37807,7 +37777,6 @@
 id: GO:0045689 ! negative regulation of antipodal cell differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
 is_a: GO:0045688 {is_inferred="true"} ! regulation of antipodal cell differentiation
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 
 [Term]
@@ -37814,7 +37783,6 @@
 id: GO:0045690 ! positive regulation of antipodal cell differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
 is_a: GO:0045688 {is_inferred="true"} ! regulation of antipodal cell differentiation
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 
 [Term]
@@ -37826,7 +37794,6 @@
 id: GO:0045692 ! negative regulation of embryo sac central cell differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
 is_a: GO:0045691 {is_inferred="true"} ! regulation of embryo sac central cell differentiation
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 
 [Term]
@@ -37833,7 +37800,6 @@
 id: GO:0045693 ! positive regulation of embryo sac central cell differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
 is_a: GO:0045691 {is_inferred="true"} ! regulation of embryo sac central cell differentiation
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 
 [Term]
@@ -37848,7 +37814,6 @@
 is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
 is_a: GO:0045694 {is_inferred="true"} ! regulation of embryo sac egg cell differentiation
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
 
 [Term]
@@ -37856,7 +37821,6 @@
 is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
 is_a: GO:0045694 {is_inferred="true"} ! regulation of embryo sac egg cell differentiation
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
 
 [Term]
@@ -37868,7 +37832,6 @@
 id: GO:0045698 ! negative regulation of synergid differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
 is_a: GO:0045697 {is_inferred="true"} ! regulation of synergid differentiation
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 
 [Term]
@@ -37875,7 +37838,6 @@
 id: GO:0045699 ! positive regulation of synergid differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
 is_a: GO:0045697 {is_inferred="true"} ! regulation of synergid differentiation
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 
 [Term]
@@ -42426,12 +42388,10 @@
 [Term]
 id: GO:0048235 ! pollen sperm cell differentiation
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0048236 ! plant-type spore development
 is_a: GO:0003006 {is_inferred="true"} ! developmental process involved in reproduction
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 is_a: GO:0048856 {is_inferred="true"} ! anatomical structure development
 
 [Term]
@@ -42830,10 +42790,6 @@
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 
 [Term]
-id: GO:0048468 ! cell development
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
-
-[Term]
 id: GO:0048469 ! cell maturation
 is_a: GO:0021700 {is_inferred="true"} ! developmental maturation
 
@@ -42904,7 +42860,6 @@
 id: GO:0048515 ! spermatid differentiation
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 is_a: GO:0030154 {is_inferred="true"} ! cell differentiation
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0048518 ! positive regulation of biological process
@@ -43070,7 +43025,6 @@
 [Term]
 id: GO:0048600 ! oocyte fate commitment
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0048601 ! oocyte morphogenesis
@@ -43160,7 +43114,6 @@
 [Term]
 id: GO:0048657 ! anther wall tapetum cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0048660 ! regulation of smooth muscle cell proliferation
@@ -45016,18 +44969,15 @@
 [Term]
 id: GO:0051147 ! regulation of muscle cell differentiation
 is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
-is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
 
 [Term]
 id: GO:0051148 ! negative regulation of muscle cell differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051147 {is_inferred="true"} ! regulation of muscle cell differentiation
 
 [Term]
 id: GO:0051149 ! positive regulation of muscle cell differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051147 {is_inferred="true"} ! regulation of muscle cell differentiation
 
 [Term]
@@ -47628,7 +47578,6 @@
 id: GO:0060008 ! Sertoli cell differentiation
 is_a: GO:0030855 {is_inferred="true"} ! epithelial cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0060009 ! Sertoli cell development
@@ -47638,7 +47587,6 @@
 [Term]
 id: GO:0060010 ! Sertoli cell fate commitment
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 is_a: GO:0072148 {is_inferred="true"} ! epithelial cell fate commitment
 
 [Term]
@@ -48184,7 +48132,6 @@
 [Term]
 id: GO:0060284 ! regulation of cell development
 is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
-is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
 
 [Term]
 id: GO:0060287 ! epithelial cilium movement involved in determination of left/right asymmetry
@@ -48815,7 +48762,6 @@
 [Term]
 id: GO:0060530 ! smooth muscle cell differentiation involved in prostate glandular acinus development
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 is_a: GO:0051145 {is_inferred="true"} ! smooth muscle cell differentiation
 
 [Term]
@@ -49318,7 +49264,6 @@
 id: GO:0060706 ! cell differentiation involved in embryonic placenta development
 is_a: GO:0030154 {is_inferred="true"} ! cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0060710 ! chorio-allantoic fusion
@@ -49454,7 +49399,6 @@
 id: GO:0060742 ! epithelial cell differentiation involved in prostate gland development
 is_a: GO:0030855 {is_inferred="true"} ! epithelial cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0060743 ! epithelial cell maturation involved in prostate gland development
@@ -55334,6 +55278,7 @@
 
 [Term]
 id: GO:0071998 ! ascospore release from ascus
+is_a: GO:0003006 {is_inferred="true"} ! developmental process involved in reproduction
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
@@ -59281,14 +59226,6 @@
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
-id: GO:0090376 ! seed trichome differentiation
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
-
-[Term]
-id: GO:0090377 ! seed trichome initiation
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
-
-[Term]
 id: GO:0090379 ! secondary cell wall biogenesis involved in seed trichome differentiation
 is_a: GO:0009834 {is_inferred="true"} ! plant-type secondary cell wall biogenesis
 is_a: GO:0022414 {is_inferred="true"} ! reproductive process
@@ -62652,7 +62589,6 @@
 is_a: GO:0010454 {is_inferred="true"} ! negative regulation of cell fate commitment
 is_a: GO:0010648 {is_inferred="true"} ! negative regulation of cell communication
 is_a: GO:0023057 {is_inferred="true"} ! negative regulation of signaling
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1900032 {is_inferred="true"} ! regulation of trichome patterning
 
@@ -88373,7 +88309,6 @@
 [Term]
 id: GO:1905208 ! negative regulation of cardiocyte differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1905207 {is_inferred="true"} ! regulation of cardiocyte differentiation
 
@@ -88380,7 +88315,6 @@
 [Term]
 id: GO:1905209 ! positive regulation of cardiocyte differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1905207 {is_inferred="true"} ! regulation of cardiocyte differentiation
 
@@ -88775,7 +88709,6 @@
 [Term]
 id: GO:1905293 ! negative regulation of neural crest cell differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1905292 {is_inferred="true"} ! regulation of neural crest cell differentiation
 
@@ -88782,7 +88715,6 @@
 [Term]
 id: GO:1905294 ! positive regulation of neural crest cell differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1905292 {is_inferred="true"} ! regulation of neural crest cell differentiation
 
@@ -95434,13 +95366,11 @@
 [Term]
 id: GO:2001050 ! negative regulation of tendon cell differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:2001049 {is_inferred="true"} ! regulation of tendon cell differentiation
 
 [Term]
 id: GO:2001051 ! positive regulation of tendon cell differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:2001049 {is_inferred="true"} ! regulation of tendon cell differentiation
 
 [Term]
------------------------------------------------------------------------
r34761 | dph | 2016-08-05 08:13:18 -0700 (Fri, 05 Aug 2016) | 2 lines

Removed the is_a relation between 'cellular develo0pmental process' and 'developmental process' that I added yesterday. It turns out that it was not necessary because 'cellular developmental process' was already a single-organism developmental process.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34761)
+++ go_inferences.obo	(working copy)
@@ -1252,6 +1252,7 @@
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 is_a: GO:0022602 {is_inferred="true"} ! ovulation cycle process
 is_a: GO:0030855 {is_inferred="true"} ! epithelial cell differentiation
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0001550 ! ovarian cumulus expansion
@@ -8425,6 +8426,7 @@
 [Term]
 id: GO:0007278 ! pole cell fate determination
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0007279 ! pole cell formation
@@ -8474,6 +8476,7 @@
 [Term]
 id: GO:0007294 ! germarium-derived oocyte fate determination
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0007295 ! growth of a germarium-derived egg chamber
@@ -8619,6 +8622,7 @@
 [Term]
 id: GO:0007531 ! mating type determination
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0007534 ! gene conversion at mating-type locus
@@ -8627,6 +8631,7 @@
 [Term]
 id: GO:0007535 ! donor selection
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0007543 ! sex determination, somatic-gonadal interaction
@@ -10475,6 +10480,7 @@
 [Term]
 id: GO:0009560 ! embryo sac egg cell differentiation
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0009568 ! amyloplast starch grain
@@ -11131,6 +11137,7 @@
 [Term]
 id: GO:0009994 ! oocyte differentiation
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0009996 ! negative regulation of cell fate specification
@@ -11296,6 +11303,7 @@
 id: GO:0010059 ! positive regulation of atrichoblast fate specification
 is_a: GO:0010058 {is_inferred="true"} ! regulation of atrichoblast fate specification
 is_a: GO:0042660 {is_inferred="true"} ! positive regulation of cell fate specification
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1903890 {is_inferred="true"} ! positive regulation of plant epidermal cell differentiation
 
@@ -11303,6 +11311,7 @@
 id: GO:0010060 ! negative regulation of atrichoblast fate specification
 is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
 is_a: GO:0010058 {is_inferred="true"} ! regulation of atrichoblast fate specification
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1903889 {is_inferred="true"} ! negative regulation of plant epidermal cell differentiation
 
@@ -11316,6 +11325,7 @@
 id: GO:0010062 ! negative regulation of trichoblast fate specification
 is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
 is_a: GO:0010061 {is_inferred="true"} ! regulation of trichoblast fate specification
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1903889 {is_inferred="true"} ! negative regulation of plant epidermal cell differentiation
 
@@ -11323,6 +11333,7 @@
 id: GO:0010063 ! positive regulation of trichoblast fate specification
 is_a: GO:0010061 {is_inferred="true"} ! regulation of trichoblast fate specification
 is_a: GO:0042660 {is_inferred="true"} ! positive regulation of cell fate specification
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1903890 {is_inferred="true"} ! positive regulation of plant epidermal cell differentiation
 
@@ -11593,6 +11604,7 @@
 [Term]
 id: GO:0010198 ! synergid death
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0010200 ! response to chitin
@@ -11628,6 +11640,7 @@
 [Term]
 id: GO:0010234 ! anther wall tapetum cell fate specification
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0010236 ! plastoquinone biosynthetic process
@@ -12031,6 +12044,7 @@
 [Term]
 id: GO:0010480 ! microsporocyte differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 is_a: GO:0048533 {is_inferred="true"} ! sporocyte differentiation
 
 [Term]
@@ -12590,6 +12604,7 @@
 [Term]
 id: GO:0010654 ! apical cell fate commitment
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0010656 ! negative regulation of muscle cell apoptotic process
@@ -12821,10 +12836,12 @@
 
 [Term]
 id: GO:0010720 ! positive regulation of cell development
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
 
 [Term]
 id: GO:0010721 ! negative regulation of cell development
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
 
 [Term]
@@ -20329,6 +20346,7 @@
 
 [Term]
 id: GO:0030220 ! platelet formation
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 is_a: GO:0048646 {is_inferred="true"} ! anatomical structure formation involved in morphogenesis
 
 [Term]
@@ -21231,11 +21249,13 @@
 id: GO:0030857 ! negative regulation of epithelial cell differentiation
 is_a: GO:0030856 {is_inferred="true"} ! regulation of epithelial cell differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 
 [Term]
 id: GO:0030858 ! positive regulation of epithelial cell differentiation
 is_a: GO:0030856 {is_inferred="true"} ! regulation of epithelial cell differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 
 [Term]
 id: GO:0030860 ! regulation of polarized epithelial cell differentiation
@@ -21695,6 +21715,7 @@
 [Term]
 id: GO:0031149 ! sorocarp stalk cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0031152 ! aggregation involved in sorocarp development
@@ -22396,6 +22417,7 @@
 [Term]
 id: GO:0031494 ! regulation of mating type switching
 is_a: GO:0010453 {is_inferred="true"} ! regulation of cell fate commitment
+is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
 is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
 
 [Term]
@@ -22402,6 +22424,7 @@
 id: GO:0031495 ! negative regulation of mating type switching
 is_a: GO:0010454 {is_inferred="true"} ! negative regulation of cell fate commitment
 is_a: GO:0031494 {is_inferred="true"} ! regulation of mating type switching
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
 
 [Term]
@@ -22408,6 +22431,7 @@
 id: GO:0031496 ! positive regulation of mating type switching
 is_a: GO:0010455 {is_inferred="true"} ! positive regulation of cell fate commitment
 is_a: GO:0031494 {is_inferred="true"} ! regulation of mating type switching
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
 
 [Term]
@@ -25859,6 +25883,7 @@
 [Term]
 id: GO:0032989 ! cellular component morphogenesis
 is_a: GO:0009653 {is_inferred="true"} ! anatomical structure morphogenesis
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0032990 ! cell part morphogenesis
@@ -26759,6 +26784,7 @@
 [Term]
 id: GO:0033327 ! Leydig cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0033329 ! kaempferol O-glucoside metabolic process
@@ -28994,6 +29020,7 @@
 [Term]
 id: GO:0035047 ! centrosomal and pronuclear rotation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0035050 ! embryonic heart tube development
@@ -29067,6 +29094,7 @@
 [Term]
 id: GO:0035155 ! negative regulation of terminal cell fate specification, open tracheal system
 is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
 
@@ -29073,6 +29101,7 @@
 [Term]
 id: GO:0035157 ! negative regulation of fusion cell fate specification
 is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
 
@@ -29155,6 +29184,7 @@
 [Term]
 id: GO:0035234 ! ectopic germ cell programmed cell death
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0035238 ! vitamin A biosynthetic process
@@ -32682,6 +32712,7 @@
 id: GO:0042683 ! negative regulation of compound eye cone cell fate specification
 is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
 is_a: GO:0042682 {is_inferred="true"} ! regulation of compound eye cone cell fate specification
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 
 [Term]
@@ -35617,6 +35648,7 @@
 [Term]
 id: GO:0044671 ! sorocarp spore cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0044673 ! 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase complex
@@ -36938,6 +36970,7 @@
 id: GO:0045476 ! nurse cell apoptotic process
 is_a: GO:0010623 {is_inferred="true"} ! programmed cell death involved in cell development
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 is_a: GO:1902742 {is_inferred="true"} ! apoptotic process involved in development
 
 [Term]
@@ -37311,7 +37344,6 @@
 
 [Term]
 id: GO:0045595 ! regulation of cell differentiation
-is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
 is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
 
 [Term]
@@ -37318,13 +37350,11 @@
 id: GO:0045596 ! negative regulation of cell differentiation
 is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
 is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 
 [Term]
 id: GO:0045597 ! positive regulation of cell differentiation
 is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
 is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 
 [Term]
 id: GO:0045598 ! regulation of fat cell differentiation
@@ -37777,6 +37807,7 @@
 id: GO:0045689 ! negative regulation of antipodal cell differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
 is_a: GO:0045688 {is_inferred="true"} ! regulation of antipodal cell differentiation
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 
 [Term]
@@ -37783,6 +37814,7 @@
 id: GO:0045690 ! positive regulation of antipodal cell differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
 is_a: GO:0045688 {is_inferred="true"} ! regulation of antipodal cell differentiation
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 
 [Term]
@@ -37794,6 +37826,7 @@
 id: GO:0045692 ! negative regulation of embryo sac central cell differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
 is_a: GO:0045691 {is_inferred="true"} ! regulation of embryo sac central cell differentiation
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 
 [Term]
@@ -37800,6 +37833,7 @@
 id: GO:0045693 ! positive regulation of embryo sac central cell differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
 is_a: GO:0045691 {is_inferred="true"} ! regulation of embryo sac central cell differentiation
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 
 [Term]
@@ -37814,6 +37848,7 @@
 is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
 is_a: GO:0045694 {is_inferred="true"} ! regulation of embryo sac egg cell differentiation
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
 
 [Term]
@@ -37821,6 +37856,7 @@
 is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
 is_a: GO:0045694 {is_inferred="true"} ! regulation of embryo sac egg cell differentiation
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
 
 [Term]
@@ -37832,6 +37868,7 @@
 id: GO:0045698 ! negative regulation of synergid differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
 is_a: GO:0045697 {is_inferred="true"} ! regulation of synergid differentiation
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 
 [Term]
@@ -37838,6 +37875,7 @@
 id: GO:0045699 ! positive regulation of synergid differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
 is_a: GO:0045697 {is_inferred="true"} ! regulation of synergid differentiation
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 
 [Term]
@@ -42388,10 +42426,12 @@
 [Term]
 id: GO:0048235 ! pollen sperm cell differentiation
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0048236 ! plant-type spore development
 is_a: GO:0003006 {is_inferred="true"} ! developmental process involved in reproduction
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 is_a: GO:0048856 {is_inferred="true"} ! anatomical structure development
 
 [Term]
@@ -42790,6 +42830,10 @@
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 
 [Term]
+id: GO:0048468 ! cell development
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
+
+[Term]
 id: GO:0048469 ! cell maturation
 is_a: GO:0021700 {is_inferred="true"} ! developmental maturation
 
@@ -42860,6 +42904,7 @@
 id: GO:0048515 ! spermatid differentiation
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 is_a: GO:0030154 {is_inferred="true"} ! cell differentiation
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0048518 ! positive regulation of biological process
@@ -43025,6 +43070,7 @@
 [Term]
 id: GO:0048600 ! oocyte fate commitment
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0048601 ! oocyte morphogenesis
@@ -43114,6 +43160,7 @@
 [Term]
 id: GO:0048657 ! anther wall tapetum cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0048660 ! regulation of smooth muscle cell proliferation
@@ -43497,10 +43544,6 @@
 is_a: GO:0048856 {is_inferred="true"} ! anatomical structure development
 
 [Term]
-id: GO:0048869 ! cellular developmental process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
-
-[Term]
 id: GO:0048878 ! chemical homeostasis
 is_a: GO:0042592 {is_inferred="true"} ! homeostatic process
 
@@ -44973,15 +45016,18 @@
 [Term]
 id: GO:0051147 ! regulation of muscle cell differentiation
 is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
+is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
 
 [Term]
 id: GO:0051148 ! negative regulation of muscle cell differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051147 {is_inferred="true"} ! regulation of muscle cell differentiation
 
 [Term]
 id: GO:0051149 ! positive regulation of muscle cell differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051147 {is_inferred="true"} ! regulation of muscle cell differentiation
 
 [Term]
@@ -47582,6 +47628,7 @@
 id: GO:0060008 ! Sertoli cell differentiation
 is_a: GO:0030855 {is_inferred="true"} ! epithelial cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0060009 ! Sertoli cell development
@@ -47591,6 +47638,7 @@
 [Term]
 id: GO:0060010 ! Sertoli cell fate commitment
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 is_a: GO:0072148 {is_inferred="true"} ! epithelial cell fate commitment
 
 [Term]
@@ -48136,6 +48184,7 @@
 [Term]
 id: GO:0060284 ! regulation of cell development
 is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
+is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
 
 [Term]
 id: GO:0060287 ! epithelial cilium movement involved in determination of left/right asymmetry
@@ -48766,6 +48815,7 @@
 [Term]
 id: GO:0060530 ! smooth muscle cell differentiation involved in prostate glandular acinus development
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 is_a: GO:0051145 {is_inferred="true"} ! smooth muscle cell differentiation
 
 [Term]
@@ -49268,6 +49318,7 @@
 id: GO:0060706 ! cell differentiation involved in embryonic placenta development
 is_a: GO:0030154 {is_inferred="true"} ! cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0060710 ! chorio-allantoic fusion
@@ -49403,6 +49454,7 @@
 id: GO:0060742 ! epithelial cell differentiation involved in prostate gland development
 is_a: GO:0030855 {is_inferred="true"} ! epithelial cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0060743 ! epithelial cell maturation involved in prostate gland development
@@ -55282,7 +55334,6 @@
 
 [Term]
 id: GO:0071998 ! ascospore release from ascus
-is_a: GO:0003006 {is_inferred="true"} ! developmental process involved in reproduction
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
@@ -59230,6 +59281,14 @@
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
+id: GO:0090376 ! seed trichome differentiation
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
+
+[Term]
+id: GO:0090377 ! seed trichome initiation
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
+
+[Term]
 id: GO:0090379 ! secondary cell wall biogenesis involved in seed trichome differentiation
 is_a: GO:0009834 {is_inferred="true"} ! plant-type secondary cell wall biogenesis
 is_a: GO:0022414 {is_inferred="true"} ! reproductive process
@@ -62593,6 +62652,7 @@
 is_a: GO:0010454 {is_inferred="true"} ! negative regulation of cell fate commitment
 is_a: GO:0010648 {is_inferred="true"} ! negative regulation of cell communication
 is_a: GO:0023057 {is_inferred="true"} ! negative regulation of signaling
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1900032 {is_inferred="true"} ! regulation of trichome patterning
 
@@ -88313,6 +88373,7 @@
 [Term]
 id: GO:1905208 ! negative regulation of cardiocyte differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1905207 {is_inferred="true"} ! regulation of cardiocyte differentiation
 
@@ -88319,6 +88380,7 @@
 [Term]
 id: GO:1905209 ! positive regulation of cardiocyte differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1905207 {is_inferred="true"} ! regulation of cardiocyte differentiation
 
@@ -88713,6 +88775,7 @@
 [Term]
 id: GO:1905293 ! negative regulation of neural crest cell differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1905292 {is_inferred="true"} ! regulation of neural crest cell differentiation
 
@@ -88719,6 +88782,7 @@
 [Term]
 id: GO:1905294 ! positive regulation of neural crest cell differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1905292 {is_inferred="true"} ! regulation of neural crest cell differentiation
 
@@ -95370,11 +95434,13 @@
 [Term]
 id: GO:2001050 ! negative regulation of tendon cell differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:2001049 {is_inferred="true"} ! regulation of tendon cell differentiation
 
 [Term]
 id: GO:2001051 ! positive regulation of tendon cell differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:2001049 {is_inferred="true"} ! regulation of tendon cell differentiation
 
 [Term]
------------------------------------------------------------------------
r34759 | paola | 2016-08-05 07:20:07 -0700 (Fri, 05 Aug 2016) | 3 lines

GH NTRs/OTRs: New cilium assembly terms and references to Reactome IDs #12572 - work in progress - added GO:0097711 ‘ciliary basal body docking’ and GO:0097712 ’vesicle targeting, trans-Golgi to periciliary membrane compartment’

changes in entailments

------------------------------------------------------------------------
r34757 | termgenie | 2016-08-05 07:05:07 -0700 (Fri, 05 Aug 2016) | 3 lines

TermGenie commit for user: pr reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34757)
+++ go_inferences.obo	(working copy)
@@ -89011,6 +89011,14 @@
 is_a: GO:0006461 {is_inferred="true"} ! protein complex assembly
 
 [Term]
+id: GO:1905352 ! ciliary necklace assembly
+is_a: GO:0006461 {is_inferred="true"} ! protein complex assembly
+
+[Term]
+id: GO:1905353 ! ciliary transition fiber assembly
+is_a: GO:0006461 {is_inferred="true"} ! protein complex assembly
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34740 | paola | 2016-08-04 09:25:57 -0700 (Thu, 04 Aug 2016) | 3 lines

GH NTRs/OTRs: New cilium assembly terms and references to Reactome IDs #12572 - work in progress - added links ‘MKS complex’ and ‘NPHP complex’ capable_of_part_of ‘Y-shaped link assembly’

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34740)
+++ go_inferences.obo	(working copy)
@@ -1252,7 +1252,6 @@
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 is_a: GO:0022602 {is_inferred="true"} ! ovulation cycle process
 is_a: GO:0030855 {is_inferred="true"} ! epithelial cell differentiation
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0001550 ! ovarian cumulus expansion
@@ -8426,7 +8425,6 @@
 [Term]
 id: GO:0007278 ! pole cell fate determination
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0007279 ! pole cell formation
@@ -8476,7 +8474,6 @@
 [Term]
 id: GO:0007294 ! germarium-derived oocyte fate determination
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0007295 ! growth of a germarium-derived egg chamber
@@ -8622,7 +8619,6 @@
 [Term]
 id: GO:0007531 ! mating type determination
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0007534 ! gene conversion at mating-type locus
@@ -8631,7 +8627,6 @@
 [Term]
 id: GO:0007535 ! donor selection
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0007543 ! sex determination, somatic-gonadal interaction
@@ -10480,7 +10475,6 @@
 [Term]
 id: GO:0009560 ! embryo sac egg cell differentiation
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0009568 ! amyloplast starch grain
@@ -11137,7 +11131,6 @@
 [Term]
 id: GO:0009994 ! oocyte differentiation
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0009996 ! negative regulation of cell fate specification
@@ -11303,7 +11296,6 @@
 id: GO:0010059 ! positive regulation of atrichoblast fate specification
 is_a: GO:0010058 {is_inferred="true"} ! regulation of atrichoblast fate specification
 is_a: GO:0042660 {is_inferred="true"} ! positive regulation of cell fate specification
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1903890 {is_inferred="true"} ! positive regulation of plant epidermal cell differentiation
 
@@ -11311,7 +11303,6 @@
 id: GO:0010060 ! negative regulation of atrichoblast fate specification
 is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
 is_a: GO:0010058 {is_inferred="true"} ! regulation of atrichoblast fate specification
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1903889 {is_inferred="true"} ! negative regulation of plant epidermal cell differentiation
 
@@ -11325,7 +11316,6 @@
 id: GO:0010062 ! negative regulation of trichoblast fate specification
 is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
 is_a: GO:0010061 {is_inferred="true"} ! regulation of trichoblast fate specification
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1903889 {is_inferred="true"} ! negative regulation of plant epidermal cell differentiation
 
@@ -11333,7 +11323,6 @@
 id: GO:0010063 ! positive regulation of trichoblast fate specification
 is_a: GO:0010061 {is_inferred="true"} ! regulation of trichoblast fate specification
 is_a: GO:0042660 {is_inferred="true"} ! positive regulation of cell fate specification
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1903890 {is_inferred="true"} ! positive regulation of plant epidermal cell differentiation
 
@@ -11604,7 +11593,6 @@
 [Term]
 id: GO:0010198 ! synergid death
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0010200 ! response to chitin
@@ -11640,7 +11628,6 @@
 [Term]
 id: GO:0010234 ! anther wall tapetum cell fate specification
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0010236 ! plastoquinone biosynthetic process
@@ -12044,7 +12031,6 @@
 [Term]
 id: GO:0010480 ! microsporocyte differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 is_a: GO:0048533 {is_inferred="true"} ! sporocyte differentiation
 
 [Term]
@@ -12604,7 +12590,6 @@
 [Term]
 id: GO:0010654 ! apical cell fate commitment
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0010656 ! negative regulation of muscle cell apoptotic process
@@ -12836,12 +12821,10 @@
 
 [Term]
 id: GO:0010720 ! positive regulation of cell development
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
 
 [Term]
 id: GO:0010721 ! negative regulation of cell development
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
 
 [Term]
@@ -20346,7 +20329,6 @@
 
 [Term]
 id: GO:0030220 ! platelet formation
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 is_a: GO:0048646 {is_inferred="true"} ! anatomical structure formation involved in morphogenesis
 
 [Term]
@@ -21249,13 +21231,11 @@
 id: GO:0030857 ! negative regulation of epithelial cell differentiation
 is_a: GO:0030856 {is_inferred="true"} ! regulation of epithelial cell differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 
 [Term]
 id: GO:0030858 ! positive regulation of epithelial cell differentiation
 is_a: GO:0030856 {is_inferred="true"} ! regulation of epithelial cell differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 
 [Term]
 id: GO:0030860 ! regulation of polarized epithelial cell differentiation
@@ -21715,7 +21695,6 @@
 [Term]
 id: GO:0031149 ! sorocarp stalk cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0031152 ! aggregation involved in sorocarp development
@@ -22417,7 +22396,6 @@
 [Term]
 id: GO:0031494 ! regulation of mating type switching
 is_a: GO:0010453 {is_inferred="true"} ! regulation of cell fate commitment
-is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
 is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
 
 [Term]
@@ -22424,7 +22402,6 @@
 id: GO:0031495 ! negative regulation of mating type switching
 is_a: GO:0010454 {is_inferred="true"} ! negative regulation of cell fate commitment
 is_a: GO:0031494 {is_inferred="true"} ! regulation of mating type switching
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
 
 [Term]
@@ -22431,7 +22408,6 @@
 id: GO:0031496 ! positive regulation of mating type switching
 is_a: GO:0010455 {is_inferred="true"} ! positive regulation of cell fate commitment
 is_a: GO:0031494 {is_inferred="true"} ! regulation of mating type switching
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
 
 [Term]
@@ -25883,7 +25859,6 @@
 [Term]
 id: GO:0032989 ! cellular component morphogenesis
 is_a: GO:0009653 {is_inferred="true"} ! anatomical structure morphogenesis
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0032990 ! cell part morphogenesis
@@ -26784,7 +26759,6 @@
 [Term]
 id: GO:0033327 ! Leydig cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0033329 ! kaempferol O-glucoside metabolic process
@@ -29020,7 +28994,6 @@
 [Term]
 id: GO:0035047 ! centrosomal and pronuclear rotation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0035050 ! embryonic heart tube development
@@ -29094,7 +29067,6 @@
 [Term]
 id: GO:0035155 ! negative regulation of terminal cell fate specification, open tracheal system
 is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
 
@@ -29101,7 +29073,6 @@
 [Term]
 id: GO:0035157 ! negative regulation of fusion cell fate specification
 is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
 
@@ -29184,7 +29155,6 @@
 [Term]
 id: GO:0035234 ! ectopic germ cell programmed cell death
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0035238 ! vitamin A biosynthetic process
@@ -32712,7 +32682,6 @@
 id: GO:0042683 ! negative regulation of compound eye cone cell fate specification
 is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
 is_a: GO:0042682 {is_inferred="true"} ! regulation of compound eye cone cell fate specification
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 
 [Term]
@@ -35648,7 +35617,6 @@
 [Term]
 id: GO:0044671 ! sorocarp spore cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0044673 ! 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase complex
@@ -36970,7 +36938,6 @@
 id: GO:0045476 ! nurse cell apoptotic process
 is_a: GO:0010623 {is_inferred="true"} ! programmed cell death involved in cell development
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 is_a: GO:1902742 {is_inferred="true"} ! apoptotic process involved in development
 
 [Term]
@@ -37344,6 +37311,7 @@
 
 [Term]
 id: GO:0045595 ! regulation of cell differentiation
+is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
 is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
 
 [Term]
@@ -37350,11 +37318,13 @@
 id: GO:0045596 ! negative regulation of cell differentiation
 is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
 is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 
 [Term]
 id: GO:0045597 ! positive regulation of cell differentiation
 is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
 is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 
 [Term]
 id: GO:0045598 ! regulation of fat cell differentiation
@@ -37807,7 +37777,6 @@
 id: GO:0045689 ! negative regulation of antipodal cell differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
 is_a: GO:0045688 {is_inferred="true"} ! regulation of antipodal cell differentiation
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 
 [Term]
@@ -37814,7 +37783,6 @@
 id: GO:0045690 ! positive regulation of antipodal cell differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
 is_a: GO:0045688 {is_inferred="true"} ! regulation of antipodal cell differentiation
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 
 [Term]
@@ -37826,7 +37794,6 @@
 id: GO:0045692 ! negative regulation of embryo sac central cell differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
 is_a: GO:0045691 {is_inferred="true"} ! regulation of embryo sac central cell differentiation
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 
 [Term]
@@ -37833,7 +37800,6 @@
 id: GO:0045693 ! positive regulation of embryo sac central cell differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
 is_a: GO:0045691 {is_inferred="true"} ! regulation of embryo sac central cell differentiation
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 
 [Term]
@@ -37848,7 +37814,6 @@
 is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
 is_a: GO:0045694 {is_inferred="true"} ! regulation of embryo sac egg cell differentiation
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
 
 [Term]
@@ -37856,7 +37821,6 @@
 is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
 is_a: GO:0045694 {is_inferred="true"} ! regulation of embryo sac egg cell differentiation
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:2000243 {is_inferred="true"} ! positive regulation of reproductive process
 
 [Term]
@@ -37868,7 +37832,6 @@
 id: GO:0045698 ! negative regulation of synergid differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
 is_a: GO:0045697 {is_inferred="true"} ! regulation of synergid differentiation
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 
 [Term]
@@ -37875,7 +37838,6 @@
 id: GO:0045699 ! positive regulation of synergid differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
 is_a: GO:0045697 {is_inferred="true"} ! regulation of synergid differentiation
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 
 [Term]
@@ -42426,12 +42388,10 @@
 [Term]
 id: GO:0048235 ! pollen sperm cell differentiation
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0048236 ! plant-type spore development
 is_a: GO:0003006 {is_inferred="true"} ! developmental process involved in reproduction
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 is_a: GO:0048856 {is_inferred="true"} ! anatomical structure development
 
 [Term]
@@ -42830,10 +42790,6 @@
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 
 [Term]
-id: GO:0048468 ! cell development
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
-
-[Term]
 id: GO:0048469 ! cell maturation
 is_a: GO:0021700 {is_inferred="true"} ! developmental maturation
 
@@ -42904,7 +42860,6 @@
 id: GO:0048515 ! spermatid differentiation
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 is_a: GO:0030154 {is_inferred="true"} ! cell differentiation
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0048518 ! positive regulation of biological process
@@ -43070,7 +43025,6 @@
 [Term]
 id: GO:0048600 ! oocyte fate commitment
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0048601 ! oocyte morphogenesis
@@ -43160,7 +43114,6 @@
 [Term]
 id: GO:0048657 ! anther wall tapetum cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0048660 ! regulation of smooth muscle cell proliferation
@@ -43544,6 +43497,10 @@
 is_a: GO:0048856 {is_inferred="true"} ! anatomical structure development
 
 [Term]
+id: GO:0048869 ! cellular developmental process
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
+
+[Term]
 id: GO:0048878 ! chemical homeostasis
 is_a: GO:0042592 {is_inferred="true"} ! homeostatic process
 
@@ -45016,18 +44973,15 @@
 [Term]
 id: GO:0051147 ! regulation of muscle cell differentiation
 is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
-is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
 
 [Term]
 id: GO:0051148 ! negative regulation of muscle cell differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051147 {is_inferred="true"} ! regulation of muscle cell differentiation
 
 [Term]
 id: GO:0051149 ! positive regulation of muscle cell differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051147 {is_inferred="true"} ! regulation of muscle cell differentiation
 
 [Term]
@@ -47628,7 +47582,6 @@
 id: GO:0060008 ! Sertoli cell differentiation
 is_a: GO:0030855 {is_inferred="true"} ! epithelial cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0060009 ! Sertoli cell development
@@ -47638,7 +47591,6 @@
 [Term]
 id: GO:0060010 ! Sertoli cell fate commitment
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 is_a: GO:0072148 {is_inferred="true"} ! epithelial cell fate commitment
 
 [Term]
@@ -48184,7 +48136,6 @@
 [Term]
 id: GO:0060284 ! regulation of cell development
 is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
-is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
 
 [Term]
 id: GO:0060287 ! epithelial cilium movement involved in determination of left/right asymmetry
@@ -48815,7 +48766,6 @@
 [Term]
 id: GO:0060530 ! smooth muscle cell differentiation involved in prostate glandular acinus development
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 is_a: GO:0051145 {is_inferred="true"} ! smooth muscle cell differentiation
 
 [Term]
@@ -49318,7 +49268,6 @@
 id: GO:0060706 ! cell differentiation involved in embryonic placenta development
 is_a: GO:0030154 {is_inferred="true"} ! cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0060710 ! chorio-allantoic fusion
@@ -49454,7 +49403,6 @@
 id: GO:0060742 ! epithelial cell differentiation involved in prostate gland development
 is_a: GO:0030855 {is_inferred="true"} ! epithelial cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 
 [Term]
 id: GO:0060743 ! epithelial cell maturation involved in prostate gland development
@@ -55334,6 +55282,7 @@
 
 [Term]
 id: GO:0071998 ! ascospore release from ascus
+is_a: GO:0003006 {is_inferred="true"} ! developmental process involved in reproduction
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
@@ -59281,14 +59230,6 @@
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
-id: GO:0090376 ! seed trichome differentiation
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
-
-[Term]
-id: GO:0090377 ! seed trichome initiation
-is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
-
-[Term]
 id: GO:0090379 ! secondary cell wall biogenesis involved in seed trichome differentiation
 is_a: GO:0009834 {is_inferred="true"} ! plant-type secondary cell wall biogenesis
 is_a: GO:0022414 {is_inferred="true"} ! reproductive process
@@ -62652,7 +62593,6 @@
 is_a: GO:0010454 {is_inferred="true"} ! negative regulation of cell fate commitment
 is_a: GO:0010648 {is_inferred="true"} ! negative regulation of cell communication
 is_a: GO:0023057 {is_inferred="true"} ! negative regulation of signaling
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1900032 {is_inferred="true"} ! regulation of trichome patterning
 
@@ -88373,7 +88313,6 @@
 [Term]
 id: GO:1905208 ! negative regulation of cardiocyte differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1905207 {is_inferred="true"} ! regulation of cardiocyte differentiation
 
@@ -88380,7 +88319,6 @@
 [Term]
 id: GO:1905209 ! positive regulation of cardiocyte differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1905207 {is_inferred="true"} ! regulation of cardiocyte differentiation
 
@@ -88775,7 +88713,6 @@
 [Term]
 id: GO:1905293 ! negative regulation of neural crest cell differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1905292 {is_inferred="true"} ! regulation of neural crest cell differentiation
 
@@ -88782,7 +88719,6 @@
 [Term]
 id: GO:1905294 ! positive regulation of neural crest cell differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1905292 {is_inferred="true"} ! regulation of neural crest cell differentiation
 
@@ -95426,13 +95362,11 @@
 [Term]
 id: GO:2001050 ! negative regulation of tendon cell differentiation
 is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:2001049 {is_inferred="true"} ! regulation of tendon cell differentiation
 
 [Term]
 id: GO:2001051 ! positive regulation of tendon cell differentiation
 is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:2001049 {is_inferred="true"} ! regulation of tendon cell differentiation
 
 [Term]
------------------------------------------------------------------------
r34737 | termgenie | 2016-08-04 09:12:38 -0700 (Thu, 04 Aug 2016) | 2 lines

TermGenie commit for user: pr reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34737)
+++ go_inferences.obo	(working copy)
@@ -89071,6 +89071,10 @@
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
 
 [Term]
+id: GO:1905350 ! Y-shaped link assembly
+is_a: GO:0006461 {is_inferred="true"} ! protein complex assembly
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34735 | paola | 2016-08-04 08:00:12 -0700 (Thu, 04 Aug 2016) | 3 lines

GH NTRs/OTRs: New cilium assembly terms and references to Reactome IDs #12572 - work in progress - edited ‘ciliary transition zone’, see ticket for details

changes in entailments

------------------------------------------------------------------------
r34733 | termgenie | 2016-08-04 07:53:14 -0700 (Thu, 04 Aug 2016) | 2 lines

TermGenie commit for user: pr reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34733)
+++ go_inferences.obo	(working copy)
@@ -89067,6 +89067,10 @@
 is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
 
 [Term]
+id: GO:1905349 ! ciliary transition zone assembly
+is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34731 | paola | 2016-08-04 07:44:37 -0700 (Thu, 04 Aug 2016) | 3 lines

GH NTRs/OTRs: New cilium assembly terms and references to Reactome IDs #12572 - work in progress:

changes in entailments

------------------------------------------------------------------------
r34729 | paola | 2016-08-04 05:56:28 -0700 (Thu, 04 Aug 2016) | 3 lines

GH Taxon rule for 'gap junction' terms #10926 - closed - see ticket for details

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34729)
+++ go_inferences.obo	(working copy)
@@ -5458,7 +5458,7 @@
 is_a: GO:0044464 {is_inferred="true"} ! cell part
 
 [Term]
-id: GO:0005922 ! connexon complex
+id: GO:0005922 ! connexin complex
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
 [Term]
------------------------------------------------------------------------
r34721 | foulger | 2016-08-04 03:31:24 -0700 (Thu, 04 Aug 2016) | 7 lines

Added ‘protein repair’ parent to new ‘protein deglycation ; GO:0036525’ term.

changes in entailments

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r34721 | foulger | 2016-08-04 03:31:24 -0700 (Thu, 04 Aug 2016) | 7 lines

Added ‘protein repair’ parent to new ‘protein deglycation ; GO:0036525’ term.

changes in entailments

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r34719 | foulger | 2016-08-04 02:53:36 -0700 (Thu, 04 Aug 2016) | 11 lines

Github: 12550

changes in entailments

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r34717 | foulger | 2016-08-04 02:09:01 -0700 (Thu, 04 Aug 2016) | 3 lines

Added initials and reference definition DBXref to GO:0090676

changes in entailments

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r34714 | termgenie | 2016-08-03 09:30:33 -0700 (Wed, 03 Aug 2016) | 2 lines

TermGenie commit for user: bhm reviewed by dph

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34714)
+++ go_inferences.obo	(working copy)
@@ -423,8 +423,8 @@
 
 [Term]
 id: GO:0000214 ! tRNA-intron endonuclease complex
-is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
 is_a: GO:1902555 {is_inferred="true"} ! endoribonuclease complex
+is_a: GO:1905348 {is_inferred="true"} ! endonuclease complex
 
 [Term]
 id: GO:0000220 ! vacuolar proton-transporting V-type ATPase, V0 domain
@@ -10300,7 +10300,7 @@
 
 [Term]
 id: GO:0009359 ! Type II site-specific deoxyribonuclease complex
-is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
+is_a: GO:1905347 {is_inferred="true"} ! endodeoxyribonuclease complex
 
 [Term]
 id: GO:0009365 ! protein histidine kinase complex
@@ -10320,7 +10320,7 @@
 
 [Term]
 id: GO:0009380 ! excinuclease repair complex
-is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
+is_a: GO:1905347 {is_inferred="true"} ! endodeoxyribonuclease complex
 is_a: GO:1990391 {is_inferred="true"} ! DNA repair complex
 
 [Term]
@@ -19404,11 +19404,11 @@
 
 [Term]
 id: GO:0019812 ! Type I site-specific deoxyribonuclease complex
-is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
+is_a: GO:1905347 {is_inferred="true"} ! endodeoxyribonuclease complex
 
 [Term]
 id: GO:0019813 ! Type III site-specific deoxyribonuclease complex
-is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
+is_a: GO:1905347 {is_inferred="true"} ! endodeoxyribonuclease complex
 
 [Term]
 id: GO:0019815 ! B cell receptor complex
@@ -23181,7 +23181,7 @@
 
 [Term]
 id: GO:0032068 ! Type IV site-specific deoxyribonuclease complex
-is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
+is_a: GO:1905347 {is_inferred="true"} ! endodeoxyribonuclease complex
 
 [Term]
 id: GO:0032069 ! regulation of nuclease activity
@@ -78078,8 +78078,8 @@
 
 [Term]
 id: GO:1903095 ! ribonuclease III complex
-is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
 is_a: GO:1902555 {is_inferred="true"} ! endoribonuclease complex
+is_a: GO:1905348 {is_inferred="true"} ! endonuclease complex
 
 [Term]
 id: GO:1903096 ! protein localization to meiotic spindle midzone
@@ -89059,6 +89059,14 @@
 is_a: GO:1905345 {is_inferred="true"} ! protein localization to cleavage furrow
 
 [Term]
+id: GO:1905347 ! endodeoxyribonuclease complex
+is_a: GO:1905348 {is_inferred="true"} ! endonuclease complex
+
+[Term]
+id: GO:1905348 ! endonuclease complex
+is_a: GO:1902494 {is_inferred="true"} ! catalytic complex
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
@@ -89418,6 +89426,7 @@
 is_a: GO:0044432 {is_inferred="true"} ! endoplasmic reticulum part
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 is_a: GO:1902555 {is_inferred="true"} ! endoribonuclease complex
+is_a: GO:1905348 {is_inferred="true"} ! endonuclease complex
 
 [Term]
 id: GO:1990333 ! mitotic checkpoint complex, CDC20-MAD2 subcomplex
------------------------------------------------------------------------
r34705 | paola | 2016-08-02 07:03:38 -0700 (Tue, 02 Aug 2016) | 2 lines

GH GO:1902560 'GMP reductase complex' needs editing #11544 - closed - see ticket for details

changes in entailments

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r34703 | dph | 2016-08-02 06:40:50 -0700 (Tue, 02 Aug 2016) | 2 lines

GH12564-closed

changes in entailments

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r34689 | termgenie | 2016-08-01 08:24:22 -0700 (Mon, 01 Aug 2016) | 3 lines

TermGenie commit for user: mah reviewed by dph

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34689)
+++ go_inferences.obo	(working copy)
@@ -89050,6 +89050,15 @@
 is_a: GO:1901523 {is_inferred="true"} ! icosanoid catabolic process
 
 [Term]
+id: GO:1905345 ! protein localization to cleavage furrow
+is_a: GO:0034394 {is_inferred="true"} ! protein localization to cell surface
+is_a: GO:0072741 {is_inferred="true"} ! protein localization to cell division site
+
+[Term]
+id: GO:1905346 ! protein localization to cleavage furrow rim
+is_a: GO:1905345 {is_inferred="true"} ! protein localization to cleavage furrow
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34679 | termgenie | 2016-07-31 17:44:20 -0700 (Sun, 31 Jul 2016) | 2 lines

TermGenie commit for user: al reviewed by dos

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34679)
+++ go_inferences.obo	(working copy)
@@ -88999,6 +88999,10 @@
 is_a: GO:0044058 {is_inferred="true"} ! regulation of digestive system process
 
 [Term]
+id: GO:1905334 ! Swi5-Sfr1 complex binding
+is_a: GO:0032403 {is_inferred="true"} ! protein complex binding
+
+[Term]
 id: GO:1905335 ! regulation of aggrephagy
 is_a: GO:0016241 {is_inferred="true"} ! regulation of macroautophagy
 
------------------------------------------------------------------------
r34677 | termgenie | 2016-07-31 17:29:00 -0700 (Sun, 31 Jul 2016) | 2 lines

TermGenie commit for user: rl reviewed by dos

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34677)
+++ go_inferences.obo	(working copy)
@@ -89016,11 +89016,12 @@
 id: GO:1905338 ! negative regulation of cohesin unloading
 is_a: GO:0045876 {is_inferred="true"} ! positive regulation of sister chromatid cohesion
 is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
+is_a: GO:1905343 {is_inferred="true"} ! regulation of cohesin unloading
 
 [Term]
 id: GO:1905339 ! positive regulation of cohesin unloading
-is_a: GO:0007063 {is_inferred="true"} ! regulation of sister chromatid cohesion
 is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
+is_a: GO:1905343 {is_inferred="true"} ! regulation of cohesin unloading
 
 [Term]
 id: GO:1905340 ! regulation of protein localization to kinetochore
@@ -89037,6 +89038,14 @@
 is_a: GO:1905340 {is_inferred="true"} ! regulation of protein localization to kinetochore
 
 [Term]
+id: GO:1905343 ! regulation of cohesin unloading
+is_a: GO:0007063 {is_inferred="true"} ! regulation of sister chromatid cohesion
+
+[Term]
+id: GO:1905344 ! prostaglandin catabolic process
+is_a: GO:1901523 {is_inferred="true"} ! icosanoid catabolic process
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34674 | davidos | 2016-07-31 17:21:02 -0700 (Sun, 31 Jul 2016) | 1 line

Fixed AP error (xref used in place of namespace)

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34674)
+++ go_inferences.obo	(working copy)
@@ -967,10 +967,6 @@
 is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
-id: GO:0000915 ! actomyosin contractile ring assembly
-is_a: GO:1902534 {is_inferred="true"} ! single-organism membrane invagination
-
-[Term]
 id: GO:0000917 ! barrier septum assembly
 is_a: GO:0090529 {is_inferred="true"} ! cell septum assembly
 
@@ -8064,7 +8060,7 @@
 
 [Term]
 id: GO:0006911 ! phagocytosis, engulfment
-is_a: GO:0010324 {is_inferred="true"} ! membrane invagination
+is_a: GO:0099024 {is_inferred="true"} ! plasma membrane invagination
 
 [Term]
 id: GO:0006921 ! cellular component disassembly involved in execution phase of apoptosis
@@ -8328,10 +8324,6 @@
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
-id: GO:0007107 ! membrane addition at site of cytokinesis
-is_a: GO:1902534 {is_inferred="true"} ! single-organism membrane invagination
-
-[Term]
 id: GO:0007116 ! regulation of cell budding
 is_a: GO:0051302 {is_inferred="true"} ! regulation of cell division
 is_a: GO:1903664 {is_inferred="true"} ! regulation of asexual reproduction
@@ -22589,10 +22581,6 @@
 is_a: GO:0044463 {is_inferred="true"} ! cell projection part
 
 [Term]
-id: GO:0031566 ! actomyosin contractile ring maintenance
-is_a: GO:1902534 {is_inferred="true"} ! single-organism membrane invagination
-
-[Term]
 id: GO:0031569 ! G2 cell size control checkpoint
 is_a: GO:0031567 {is_inferred="true"} ! mitotic cell size control checkpoint
 
@@ -25774,7 +25762,6 @@
 [Term]
 id: GO:0032954 ! regulation of cytokinetic process
 is_a: GO:0032465 {is_inferred="true"} ! regulation of cytokinesis
-is_a: GO:1905153 {is_inferred="true"} ! regulation of membrane invagination
 
 [Term]
 id: GO:0032955 ! regulation of barrier septum assembly
@@ -61730,10 +61717,22 @@
 is_a: GO:0099022 {is_inferred="true"} ! vesicle tethering
 
 [Term]
+id: GO:0099043 ! cargo loading involved in clathrin-dependent endocytosis
+is_a: GO:0035652 {is_inferred="true"} ! cargo loading into clathrin-coated vesicle
+
+[Term]
 id: GO:0099044 ! vesicle tethering to endoplasmic reticulum
 is_a: GO:0099022 {is_inferred="true"} ! vesicle tethering
 
 [Term]
+id: GO:0099049 ! clathrin coat assembly involved in endocytosis
+is_a: GO:0048268 {is_inferred="true"} ! clathrin coat assembly
+
+[Term]
+id: GO:0099052 ! vesicle scission involved in clathrin-mediated endocytosis
+is_a: GO:0099051 {is_inferred="true"} ! vesicle scission involved in endocytosis
+
+[Term]
 id: GO:0099055 ! integral component of postsynaptic membrane
 is_a: GO:0005887 {is_inferred="true"} ! integral component of plasma membrane
 is_a: GO:0098936 {is_inferred="true"} ! intrinsic component of postsynaptic membrane
@@ -63416,9 +63415,9 @@
 is_a: GO:1900183 {is_inferred="true"} ! regulation of xanthone-containing compound biosynthetic process
 
 [Term]
-id: GO:1900186 ! negative regulation of clathrin-mediated endocytosis
+id: GO:1900186 ! negative regulation of clathrin-dependent endocytosis
 is_a: GO:0048261 {is_inferred="true"} ! negative regulation of receptor-mediated endocytosis
-is_a: GO:2000369 {is_inferred="true"} ! regulation of clathrin-mediated endocytosis
+is_a: GO:2000369 {is_inferred="true"} ! regulation of clathrin-dependent endocytosis
 
 [Term]
 id: GO:1900187 ! regulation of cell adhesion involved in single-species biofilm formation
@@ -63686,11 +63685,11 @@
 [Term]
 id: GO:1900242 ! regulation of synaptic vesicle endocytosis
 is_a: GO:1903421 {is_inferred="true"} ! regulation of synaptic vesicle recycling
-is_a: GO:2000369 {is_inferred="true"} ! regulation of clathrin-mediated endocytosis
+is_a: GO:2000369 {is_inferred="true"} ! regulation of clathrin-dependent endocytosis
 
 [Term]
 id: GO:1900243 ! negative regulation of synaptic vesicle endocytosis
-is_a: GO:1900186 {is_inferred="true"} ! negative regulation of clathrin-mediated endocytosis
+is_a: GO:1900186 {is_inferred="true"} ! negative regulation of clathrin-dependent endocytosis
 is_a: GO:1900242 {is_inferred="true"} ! regulation of synaptic vesicle endocytosis
 is_a: GO:1903422 {is_inferred="true"} ! negative regulation of synaptic vesicle recycling
 
@@ -63698,7 +63697,7 @@
 id: GO:1900244 ! positive regulation of synaptic vesicle endocytosis
 is_a: GO:1900242 {is_inferred="true"} ! regulation of synaptic vesicle endocytosis
 is_a: GO:1903423 {is_inferred="true"} ! positive regulation of synaptic vesicle recycling
-is_a: GO:2000370 {is_inferred="true"} ! positive regulation of clathrin-mediated endocytosis
+is_a: GO:2000370 {is_inferred="true"} ! positive regulation of clathrin-dependent endocytosis
 
 [Term]
 id: GO:1900245 ! positive regulation of MDA-5 signaling pathway
@@ -70989,13 +70988,11 @@
 id: GO:1901649 ! negative regulation of actomyosin contractile ring localization
 is_a: GO:0032466 {is_inferred="true"} ! negative regulation of cytokinesis
 is_a: GO:1901648 {is_inferred="true"} ! regulation of actomyosin contractile ring localization
-is_a: GO:1905154 {is_inferred="true"} ! negative regulation of membrane invagination
 
 [Term]
 id: GO:1901650 ! positive regulation of actomyosin contractile ring localization
 is_a: GO:0032467 {is_inferred="true"} ! positive regulation of cytokinesis
 is_a: GO:1901648 {is_inferred="true"} ! regulation of actomyosin contractile ring localization
-is_a: GO:1905155 {is_inferred="true"} ! positive regulation of membrane invagination
 
 [Term]
 id: GO:1901651 ! regulation of mitotic chromosome decondensation
@@ -72259,19 +72256,20 @@
 id: GO:1901891 ! regulation of cell septum assembly
 is_a: GO:0032954 {is_inferred="true"} ! regulation of cytokinetic process
 is_a: GO:0044087 {is_inferred="true"} ! regulation of cellular component biogenesis
+is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 
 [Term]
 id: GO:1901892 ! negative regulation of cell septum assembly
 is_a: GO:0032466 {is_inferred="true"} ! negative regulation of cytokinesis
+is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:1901891 {is_inferred="true"} ! regulation of cell septum assembly
-is_a: GO:1905154 {is_inferred="true"} ! negative regulation of membrane invagination
 
 [Term]
 id: GO:1901893 ! positive regulation of cell septum assembly
 is_a: GO:0032467 {is_inferred="true"} ! positive regulation of cytokinesis
 is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
+is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 is_a: GO:1901891 {is_inferred="true"} ! regulation of cell septum assembly
-is_a: GO:1905155 {is_inferred="true"} ! positive regulation of membrane invagination
 
 [Term]
 id: GO:1901894 ! regulation of calcium-transporting ATPase activity
@@ -75796,7 +75794,6 @@
 id: GO:1902621 ! actomyosin contractile ring disassembly
 is_a: GO:0022411 {is_inferred="true"} ! cellular component disassembly
 is_a: GO:0044837 {is_inferred="true"} ! actomyosin contractile ring organization
-is_a: GO:1902534 {is_inferred="true"} ! single-organism membrane invagination
 
 [Term]
 id: GO:1902622 ! regulation of neutrophil migration
@@ -79692,13 +79689,11 @@
 id: GO:1903437 ! negative regulation of mitotic cytokinetic process
 is_a: GO:1902413 {is_inferred="true"} ! negative regulation of mitotic cytokinesis
 is_a: GO:1903436 {is_inferred="true"} ! regulation of mitotic cytokinetic process
-is_a: GO:1905154 {is_inferred="true"} ! negative regulation of membrane invagination
 
 [Term]
 id: GO:1903438 ! positive regulation of mitotic cytokinetic process
 is_a: GO:1903436 {is_inferred="true"} ! regulation of mitotic cytokinetic process
 is_a: GO:1903490 {is_inferred="true"} ! positive regulation of mitotic cytokinesis
-is_a: GO:1905155 {is_inferred="true"} ! positive regulation of membrane invagination
 
 [Term]
 id: GO:1903441 ! protein localization to ciliary membrane
@@ -79908,10 +79903,12 @@
 
 [Term]
 id: GO:1903483 ! regulation of maintenance of mitotic actomyosin contractile ring localization
+is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 is_a: GO:1902471 {is_inferred="true"} ! regulation of mitotic actomyosin contractile ring localization
 
 [Term]
 id: GO:1903484 ! negative regulation of maintenance of mitotic actomyosin contractile ring localization
+is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:1901649 {is_inferred="true"} ! negative regulation of actomyosin contractile ring localization
 is_a: GO:1903437 {is_inferred="true"} ! negative regulation of mitotic cytokinetic process
 is_a: GO:1903483 {is_inferred="true"} ! regulation of maintenance of mitotic actomyosin contractile ring localization
@@ -79918,6 +79915,7 @@
 
 [Term]
 id: GO:1903485 ! positive regulation of maintenance of mitotic actomyosin contractile ring localization
+is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 is_a: GO:1901650 {is_inferred="true"} ! positive regulation of actomyosin contractile ring localization
 is_a: GO:1903438 {is_inferred="true"} ! positive regulation of mitotic cytokinetic process
 is_a: GO:1903483 {is_inferred="true"} ! regulation of maintenance of mitotic actomyosin contractile ring localization
@@ -86315,6 +86313,7 @@
 
 [Term]
 id: GO:1904789 ! regulation of mitotic actomyosin contractile ring maintenance
+is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 is_a: GO:1903436 {is_inferred="true"} ! regulation of mitotic cytokinetic process
 
 [Term]
@@ -89837,7 +89836,7 @@
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
 
 [Term]
-id: GO:1990771 ! clathrin-mediated extracellular exosome endocytosis
+id: GO:1990771 ! clathrin-dependent extracellular exosome endocytosis
 is_a: GO:0051650 {is_inferred="true"} ! establishment of vesicle localization
 
 [Term]
@@ -90394,12 +90393,10 @@
 
 [Term]
 id: GO:2000075 ! negative regulation of cytokinesis, site selection
-is_a: GO:1905154 {is_inferred="true"} ! negative regulation of membrane invagination
 is_a: GO:2000073 {is_inferred="true"} ! regulation of cytokinesis, site selection
 
 [Term]
 id: GO:2000076 ! positive regulation cytokinesis, site selection
-is_a: GO:1905155 {is_inferred="true"} ! positive regulation of membrane invagination
 is_a: GO:2000073 {is_inferred="true"} ! regulation of cytokinesis, site selection
 
 [Term]
@@ -91935,13 +91932,13 @@
 is_a: GO:2000367 {is_inferred="true"} ! regulation of acrosomal vesicle exocytosis
 
 [Term]
-id: GO:2000369 ! regulation of clathrin-mediated endocytosis
+id: GO:2000369 ! regulation of clathrin-dependent endocytosis
 is_a: GO:0048259 {is_inferred="true"} ! regulation of receptor-mediated endocytosis
 
 [Term]
-id: GO:2000370 ! positive regulation of clathrin-mediated endocytosis
+id: GO:2000370 ! positive regulation of clathrin-dependent endocytosis
 is_a: GO:0048260 {is_inferred="true"} ! positive regulation of receptor-mediated endocytosis
-is_a: GO:2000369 {is_inferred="true"} ! regulation of clathrin-mediated endocytosis
+is_a: GO:2000369 {is_inferred="true"} ! regulation of clathrin-dependent endocytosis
 
 [Term]
 id: GO:2000371 ! regulation of DNA topoisomerase (ATP-hydrolyzing) activity
@@ -92258,7 +92255,6 @@
 id: GO:2000432 ! negative regulation of cytokinesis, actomyosin contractile ring assembly
 is_a: GO:0032466 {is_inferred="true"} ! negative regulation of cytokinesis
 is_a: GO:0051494 {is_inferred="true"} ! negative regulation of cytoskeleton organization
-is_a: GO:1905154 {is_inferred="true"} ! negative regulation of membrane invagination
 is_a: GO:2000431 {is_inferred="true"} ! regulation of cytokinesis, actomyosin contractile ring assembly
 
 [Term]
@@ -92266,7 +92262,6 @@
 is_a: GO:0032467 {is_inferred="true"} ! positive regulation of cytokinesis
 is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
 is_a: GO:0051495 {is_inferred="true"} ! positive regulation of cytoskeleton organization
-is_a: GO:1905155 {is_inferred="true"} ! positive regulation of membrane invagination
 is_a: GO:2000431 {is_inferred="true"} ! regulation of cytokinesis, actomyosin contractile ring assembly
 
 [Term]
@@ -96545,16 +96540,16 @@
 
 [Term]
 id: GO:2001286 ! regulation of caveolin-mediated endocytosis
-is_a: GO:0048259 {is_inferred="true"} ! regulation of receptor-mediated endocytosis
+is_a: GO:0030100 {is_inferred="true"} ! regulation of endocytosis
 
 [Term]
 id: GO:2001287 ! negative regulation of caveolin-mediated endocytosis
-is_a: GO:0048261 {is_inferred="true"} ! negative regulation of receptor-mediated endocytosis
+is_a: GO:0045806 {is_inferred="true"} ! negative regulation of endocytosis
 is_a: GO:2001286 {is_inferred="true"} ! regulation of caveolin-mediated endocytosis
 
 [Term]
 id: GO:2001288 ! positive regulation of caveolin-mediated endocytosis
-is_a: GO:0048260 {is_inferred="true"} ! positive regulation of receptor-mediated endocytosis
+is_a: GO:0045807 {is_inferred="true"} ! positive regulation of endocytosis
 is_a: GO:2001286 {is_inferred="true"} ! regulation of caveolin-mediated endocytosis
 
 [Term]
------------------------------------------------------------------------
r34625 | termgenie | 2016-07-28 11:21:03 -0700 (Thu, 28 Jul 2016) | 4 lines

TermGenie commit for user: es reviewed by dos

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34625)
+++ go_inferences.obo	(working copy)
@@ -89000,6 +89000,44 @@
 is_a: GO:0044058 {is_inferred="true"} ! regulation of digestive system process
 
 [Term]
+id: GO:1905335 ! regulation of aggrephagy
+is_a: GO:0016241 {is_inferred="true"} ! regulation of macroautophagy
+
+[Term]
+id: GO:1905336 ! negative regulation of aggrephagy
+is_a: GO:0016242 {is_inferred="true"} ! negative regulation of macroautophagy
+is_a: GO:1905335 {is_inferred="true"} ! regulation of aggrephagy
+
+[Term]
+id: GO:1905337 ! positive regulation of aggrephagy
+is_a: GO:0016239 {is_inferred="true"} ! positive regulation of macroautophagy
+is_a: GO:1905335 {is_inferred="true"} ! regulation of aggrephagy
+
+[Term]
+id: GO:1905338 ! negative regulation of cohesin unloading
+is_a: GO:0045876 {is_inferred="true"} ! positive regulation of sister chromatid cohesion
+is_a: GO:0048519 {is_inferred="true"} ! negative regulation of biological process
+
+[Term]
+id: GO:1905339 ! positive regulation of cohesin unloading
+is_a: GO:0007063 {is_inferred="true"} ! regulation of sister chromatid cohesion
+is_a: GO:0048518 {is_inferred="true"} ! positive regulation of biological process
+
+[Term]
+id: GO:1905340 ! regulation of protein localization to kinetochore
+is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
+
+[Term]
+id: GO:1905341 ! negative regulation of protein localization to kinetochore
+is_a: GO:1903828 {is_inferred="true"} ! negative regulation of cellular protein localization
+is_a: GO:1905340 {is_inferred="true"} ! regulation of protein localization to kinetochore
+
+[Term]
+id: GO:1905342 ! positive regulation of protein localization to kinetochore
+is_a: GO:1903829 {is_inferred="true"} ! positive regulation of cellular protein localization
+is_a: GO:1905340 {is_inferred="true"} ! regulation of protein localization to kinetochore
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
@@ -89978,6 +90016,16 @@
 is_a: GO:0098637 {is_inferred="true"} ! protein complex involved in cell-matrix adhesion
 
 [Term]
+id: GO:1990975 ! establishment of protein localization to mitotic spindle pole body
+is_a: GO:0071989 {is_inferred="true"} ! establishment of protein localization to spindle pole body
+is_a: GO:1902440 {is_inferred="true"} ! protein localization to mitotic spindle pole body
+
+[Term]
+id: GO:1990976 ! protein transport along microtubule to mitotic spindle pole body
+is_a: GO:1990852 {is_inferred="true"} ! protein transport along microtubule to spindle pole body
+is_a: GO:1990975 {is_inferred="true"} ! establishment of protein localization to mitotic spindle pole body
+
+[Term]
 id: GO:2000001 ! regulation of DNA damage checkpoint
 is_a: GO:1901976 {is_inferred="true"} ! regulation of cell cycle checkpoint
 is_a: GO:2001020 {is_inferred="true"} ! regulation of response to DNA damage stimulus
------------------------------------------------------------------------
r34609 | davidos | 2016-07-27 14:35:08 -0700 (Wed, 27 Jul 2016) | 1 line

Corrected AP error (comment -> dbxref)

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34609)
+++ go_inferences.obo	(working copy)
@@ -306,6 +306,10 @@
 is_a: GO:0005940 {is_inferred="true"} ! septin ring
 
 [Term]
+id: GO:0000145 ! exocyst
+is_a: GO:0099023 {is_inferred="true"} ! tethring complex
+
+[Term]
 id: GO:0000147 ! actin cortical patch assembly
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
 is_a: GO:0044396 {is_inferred="true"} ! actin cortical patch organization
@@ -963,6 +967,10 @@
 is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
+id: GO:0000915 ! actomyosin contractile ring assembly
+is_a: GO:1902534 {is_inferred="true"} ! single-organism membrane invagination
+
+[Term]
 id: GO:0000917 ! barrier septum assembly
 is_a: GO:0090529 {is_inferred="true"} ! cell septum assembly
 
@@ -994,6 +1002,11 @@
 is_a: GO:0008275 {is_inferred="true"} ! gamma-tubulin small complex
 
 [Term]
+id: GO:0000938 ! GARP complex
+is_a: GO:0044433 {is_inferred="true"} ! cytoplasmic vesicle part
+is_a: GO:0099023 {is_inferred="true"} ! tethring complex
+
+[Term]
 id: GO:0000941 ! condensed nuclear chromosome inner kinetochore
 is_a: GO:0000939 {is_inferred="true"} ! condensed chromosome inner kinetochore
 is_a: GO:0044454 {is_inferred="true"} ! nuclear chromosome part
@@ -8113,6 +8126,10 @@
 is_a: GO:0006996 {is_inferred="true"} ! organelle organization
 
 [Term]
+id: GO:0006999 ! nuclear pore organization
+is_a: GO:0071822 {is_inferred="true"} ! protein complex subunit organization
+
+[Term]
 id: GO:0007005 ! mitochondrion organization
 is_a: GO:0006996 {is_inferred="true"} ! organelle organization
 
@@ -8311,6 +8328,10 @@
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
+id: GO:0007107 ! membrane addition at site of cytokinesis
+is_a: GO:1902534 {is_inferred="true"} ! single-organism membrane invagination
+
+[Term]
 id: GO:0007116 ! regulation of cell budding
 is_a: GO:0051302 {is_inferred="true"} ! regulation of cell division
 is_a: GO:1903664 {is_inferred="true"} ! regulation of asexual reproduction
@@ -17008,6 +17029,10 @@
 is_a: GO:1904949 {is_inferred="true"} ! ATPase complex
 
 [Term]
+id: GO:0017119 ! Golgi transport complex
+is_a: GO:0099023 {is_inferred="true"} ! tethring complex
+
+[Term]
 id: GO:0017122 ! protein N-acetylglucosaminyltransferase complex
 is_a: GO:1990234 {is_inferred="true"} ! transferase complex
 
@@ -19988,6 +20013,10 @@
 is_a: GO:0055067 {is_inferred="true"} ! monovalent inorganic cation homeostasis
 
 [Term]
+id: GO:0030008 ! TRAPP complex
+is_a: GO:0099023 {is_inferred="true"} ! tethring complex
+
+[Term]
 id: GO:0030015 ! CCR4-NOT core complex
 is_a: GO:0044424 {is_inferred="true"} ! intracellular part
 
@@ -21316,6 +21345,7 @@
 [Term]
 id: GO:0030897 ! HOPS complex
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
+is_a: GO:0099023 {is_inferred="true"} ! tethring complex
 
 [Term]
 id: GO:0030904 ! retromer complex
@@ -22559,6 +22589,10 @@
 is_a: GO:0044463 {is_inferred="true"} ! cell projection part
 
 [Term]
+id: GO:0031566 ! actomyosin contractile ring maintenance
+is_a: GO:1902534 {is_inferred="true"} ! single-organism membrane invagination
+
+[Term]
 id: GO:0031569 ! G2 cell size control checkpoint
 is_a: GO:0031567 {is_inferred="true"} ! mitotic cell size control checkpoint
 
@@ -25740,6 +25774,7 @@
 [Term]
 id: GO:0032954 ! regulation of cytokinetic process
 is_a: GO:0032465 {is_inferred="true"} ! regulation of cytokinesis
+is_a: GO:1905153 {is_inferred="true"} ! regulation of membrane invagination
 
 [Term]
 id: GO:0032955 ! regulation of barrier septum assembly
@@ -26585,6 +26620,10 @@
 is_a: GO:0090329 {is_inferred="true"} ! regulation of DNA-dependent DNA replication
 
 [Term]
+id: GO:0033263 ! CORVET complex
+is_a: GO:0099023 {is_inferred="true"} ! tethring complex
+
+[Term]
 id: GO:0033265 ! choline binding
 is_a: GO:0070405 {is_inferred="true"} ! ammonium ion binding
 
@@ -28071,6 +28110,11 @@
 is_a: GO:1901700 {is_inferred="true"} ! response to oxygen-containing compound
 
 [Term]
+id: GO:0034203 ! glycolipid translocation
+is_a: GO:0034204 {is_inferred="true"} ! lipid translocation
+is_a: GO:0046836 {is_inferred="true"} ! glycolipid transport
+
+[Term]
 id: GO:0034213 ! quinolinate catabolic process
 is_a: GO:0043649 {is_inferred="true"} ! dicarboxylic acid catabolic process
 is_a: GO:0046874 {is_inferred="true"} ! quinolinate metabolic process
@@ -36420,6 +36464,11 @@
 is_a: GO:0009437 {is_inferred="true"} ! carnitine metabolic process
 
 [Term]
+id: GO:0045332 ! phospholipid translocation
+is_a: GO:0015914 {is_inferred="true"} ! phospholipid transport
+is_a: GO:0034204 {is_inferred="true"} ! lipid translocation
+
+[Term]
 id: GO:0045337 ! farnesyl diphosphate biosynthetic process
 is_a: GO:0008654 {is_inferred="true"} ! phospholipid biosynthetic process
 is_a: GO:0016114 {is_inferred="true"} ! terpenoid biosynthetic process
@@ -41333,6 +41382,11 @@
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 
 [Term]
+id: GO:0046623 ! sphingolipid-translocating ATPase activity
+is_a: GO:0004012 {is_inferred="true"} ! phospholipid-translocating ATPase activity
+is_a: GO:0046624 {is_inferred="true"} ! sphingolipid transporter activity
+
+[Term]
 id: GO:0046624 ! sphingolipid transporter activity
 is_a: GO:0005319 {is_inferred="true"} ! lipid transporter activity
 
@@ -53027,6 +53081,10 @@
 is_a: GO:0070926 {is_inferred="true"} ! regulation of ATP:ADP antiporter activity
 
 [Term]
+id: GO:0070939 ! Dsl1/NZR complex
+is_a: GO:0099023 {is_inferred="true"} ! tethring complex
+
+[Term]
 id: GO:0070948 ! regulation of neutrophil mediated cytotoxicity
 is_a: GO:0001910 {is_inferred="true"} ! regulation of leukocyte mediated cytotoxicity
 is_a: GO:0002886 {is_inferred="true"} ! regulation of myeloid leukocyte mediated immunity
@@ -59481,6 +59539,10 @@
 is_a: GO:0010631 {is_inferred="true"} ! epithelial cell migration
 
 [Term]
+id: GO:0090522 ! vesicle tethering involved in exocytosis
+is_a: GO:0099022 {is_inferred="true"} ! vesicle tethering
+
+[Term]
 id: GO:0090525 ! regulation of glycolysis involved in cellular glucose homeostasis
 is_a: GO:0006110 {is_inferred="true"} ! regulation of glycolytic process
 
@@ -59502,9 +59564,20 @@
 
 [Term]
 id: GO:0090554 ! phosphatidylcholine-translocating ATPase activity
+is_a: GO:0004012 {is_inferred="true"} ! phospholipid-translocating ATPase activity
 is_a: GO:0008525 {is_inferred="true"} ! phosphatidylcholine transporter activity
 
 [Term]
+id: GO:0090555 ! phosphatidylethanolamine-translocating ATPase activity
+is_a: GO:0004012 {is_inferred="true"} ! phospholipid-translocating ATPase activity
+is_a: GO:1904121 {is_inferred="true"} ! phosphatidylethanolamine transporter activity
+
+[Term]
+id: GO:0090556 ! phosphatidylserine-translocating ATPase activity
+is_a: GO:0004012 {is_inferred="true"} ! phospholipid-translocating ATPase activity
+is_a: GO:0015247 {is_inferred="true"} ! aminophospholipid transporter activity
+
+[Term]
 id: GO:0090596 ! sensory organ morphogenesis
 is_a: GO:0009887 {is_inferred="true"} ! organ morphogenesis
 
@@ -61469,7 +61542,7 @@
 is_a: GO:0098982 {is_inferred="true"} ! GABA-ergic synapse
 
 [Term]
-id: GO:0098985 ! asymmetric, glutamateric, excitatory synapse
+id: GO:0098985 ! asymmetric, glutamatergic, excitatory synapse
 is_a: GO:0060076 {is_inferred="true"} ! excitatory synapse
 is_a: GO:0098978 {is_inferred="true"} ! glutamatergic synapse
 
@@ -61569,6 +61642,10 @@
 is_a: GO:0044448 {is_inferred="true"} ! cell cortex part
 
 [Term]
+id: GO:0099023 ! tethring complex
+is_a: GO:0043234 {is_inferred="true"} ! protein complex
+
+[Term]
 id: GO:0099025 ! anchored component of postsynaptic membrane
 is_a: GO:0046658 {is_inferred="true"} ! anchored component of plasma membrane
 is_a: GO:0098936 {is_inferred="true"} ! intrinsic component of postsynaptic membrane
@@ -61634,6 +61711,29 @@
 is_a: GO:0098955 {is_inferred="true"} ! intrinsic component of presynaptic endosome membrane
 
 [Term]
+id: GO:0099038 ! ceramide-translocating ATPase activity
+is_a: GO:0035620 {is_inferred="true"} ! ceramide transporter activity
+is_a: GO:0046623 {is_inferred="true"} ! sphingolipid-translocating ATPase activity
+
+[Term]
+id: GO:0099039 ! sphingolipid translocation
+is_a: GO:0034204 {is_inferred="true"} ! lipid translocation
+is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
+
+[Term]
+id: GO:0099040 ! ceramide translocation
+is_a: GO:0035627 {is_inferred="true"} ! ceramide transport
+is_a: GO:0099039 {is_inferred="true"} ! sphingolipid translocation
+
+[Term]
+id: GO:0099041 ! vesicle tethering to Golgi
+is_a: GO:0099022 {is_inferred="true"} ! vesicle tethering
+
+[Term]
+id: GO:0099044 ! vesicle tethering to endoplasmic reticulum
+is_a: GO:0099022 {is_inferred="true"} ! vesicle tethering
+
+[Term]
 id: GO:0099055 ! integral component of postsynaptic membrane
 is_a: GO:0005887 {is_inferred="true"} ! integral component of plasma membrane
 is_a: GO:0098936 {is_inferred="true"} ! intrinsic component of postsynaptic membrane
@@ -70889,11 +70989,13 @@
 id: GO:1901649 ! negative regulation of actomyosin contractile ring localization
 is_a: GO:0032466 {is_inferred="true"} ! negative regulation of cytokinesis
 is_a: GO:1901648 {is_inferred="true"} ! regulation of actomyosin contractile ring localization
+is_a: GO:1905154 {is_inferred="true"} ! negative regulation of membrane invagination
 
 [Term]
 id: GO:1901650 ! positive regulation of actomyosin contractile ring localization
 is_a: GO:0032467 {is_inferred="true"} ! positive regulation of cytokinesis
 is_a: GO:1901648 {is_inferred="true"} ! regulation of actomyosin contractile ring localization
+is_a: GO:1905155 {is_inferred="true"} ! positive regulation of membrane invagination
 
 [Term]
 id: GO:1901651 ! regulation of mitotic chromosome decondensation
@@ -72157,20 +72259,19 @@
 id: GO:1901891 ! regulation of cell septum assembly
 is_a: GO:0032954 {is_inferred="true"} ! regulation of cytokinetic process
 is_a: GO:0044087 {is_inferred="true"} ! regulation of cellular component biogenesis
-is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 
 [Term]
 id: GO:1901892 ! negative regulation of cell septum assembly
 is_a: GO:0032466 {is_inferred="true"} ! negative regulation of cytokinesis
-is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:1901891 {is_inferred="true"} ! regulation of cell septum assembly
+is_a: GO:1905154 {is_inferred="true"} ! negative regulation of membrane invagination
 
 [Term]
 id: GO:1901893 ! positive regulation of cell septum assembly
 is_a: GO:0032467 {is_inferred="true"} ! positive regulation of cytokinesis
 is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
-is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 is_a: GO:1901891 {is_inferred="true"} ! regulation of cell septum assembly
+is_a: GO:1905155 {is_inferred="true"} ! positive regulation of membrane invagination
 
 [Term]
 id: GO:1901894 ! regulation of calcium-transporting ATPase activity
@@ -75695,6 +75796,7 @@
 id: GO:1902621 ! actomyosin contractile ring disassembly
 is_a: GO:0022411 {is_inferred="true"} ! cellular component disassembly
 is_a: GO:0044837 {is_inferred="true"} ! actomyosin contractile ring organization
+is_a: GO:1902534 {is_inferred="true"} ! single-organism membrane invagination
 
 [Term]
 id: GO:1902622 ! regulation of neutrophil migration
@@ -79590,11 +79692,13 @@
 id: GO:1903437 ! negative regulation of mitotic cytokinetic process
 is_a: GO:1902413 {is_inferred="true"} ! negative regulation of mitotic cytokinesis
 is_a: GO:1903436 {is_inferred="true"} ! regulation of mitotic cytokinetic process
+is_a: GO:1905154 {is_inferred="true"} ! negative regulation of membrane invagination
 
 [Term]
 id: GO:1903438 ! positive regulation of mitotic cytokinetic process
 is_a: GO:1903436 {is_inferred="true"} ! regulation of mitotic cytokinetic process
 is_a: GO:1903490 {is_inferred="true"} ! positive regulation of mitotic cytokinesis
+is_a: GO:1905155 {is_inferred="true"} ! positive regulation of membrane invagination
 
 [Term]
 id: GO:1903441 ! protein localization to ciliary membrane
@@ -79804,12 +79908,10 @@
 
 [Term]
 id: GO:1903483 ! regulation of maintenance of mitotic actomyosin contractile ring localization
-is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 is_a: GO:1902471 {is_inferred="true"} ! regulation of mitotic actomyosin contractile ring localization
 
 [Term]
 id: GO:1903484 ! negative regulation of maintenance of mitotic actomyosin contractile ring localization
-is_a: GO:0051129 {is_inferred="true"} ! negative regulation of cellular component organization
 is_a: GO:1901649 {is_inferred="true"} ! negative regulation of actomyosin contractile ring localization
 is_a: GO:1903437 {is_inferred="true"} ! negative regulation of mitotic cytokinetic process
 is_a: GO:1903483 {is_inferred="true"} ! regulation of maintenance of mitotic actomyosin contractile ring localization
@@ -79816,7 +79918,6 @@
 
 [Term]
 id: GO:1903485 ! positive regulation of maintenance of mitotic actomyosin contractile ring localization
-is_a: GO:0051130 {is_inferred="true"} ! positive regulation of cellular component organization
 is_a: GO:1901650 {is_inferred="true"} ! positive regulation of actomyosin contractile ring localization
 is_a: GO:1903438 {is_inferred="true"} ! positive regulation of mitotic cytokinetic process
 is_a: GO:1903483 {is_inferred="true"} ! regulation of maintenance of mitotic actomyosin contractile ring localization
@@ -86214,7 +86315,6 @@
 
 [Term]
 id: GO:1904789 ! regulation of mitotic actomyosin contractile ring maintenance
-is_a: GO:0051128 {is_inferred="true"} ! regulation of cellular component organization
 is_a: GO:1903436 {is_inferred="true"} ! regulation of mitotic cytokinetic process
 
 [Term]
@@ -90246,10 +90346,12 @@
 
 [Term]
 id: GO:2000075 ! negative regulation of cytokinesis, site selection
+is_a: GO:1905154 {is_inferred="true"} ! negative regulation of membrane invagination
 is_a: GO:2000073 {is_inferred="true"} ! regulation of cytokinesis, site selection
 
 [Term]
 id: GO:2000076 ! positive regulation cytokinesis, site selection
+is_a: GO:1905155 {is_inferred="true"} ! positive regulation of membrane invagination
 is_a: GO:2000073 {is_inferred="true"} ! regulation of cytokinesis, site selection
 
 [Term]
@@ -92108,6 +92210,7 @@
 id: GO:2000432 ! negative regulation of cytokinesis, actomyosin contractile ring assembly
 is_a: GO:0032466 {is_inferred="true"} ! negative regulation of cytokinesis
 is_a: GO:0051494 {is_inferred="true"} ! negative regulation of cytoskeleton organization
+is_a: GO:1905154 {is_inferred="true"} ! negative regulation of membrane invagination
 is_a: GO:2000431 {is_inferred="true"} ! regulation of cytokinesis, actomyosin contractile ring assembly
 
 [Term]
@@ -92115,6 +92218,7 @@
 is_a: GO:0032467 {is_inferred="true"} ! positive regulation of cytokinesis
 is_a: GO:0044089 {is_inferred="true"} ! positive regulation of cellular component biogenesis
 is_a: GO:0051495 {is_inferred="true"} ! positive regulation of cytoskeleton organization
+is_a: GO:1905155 {is_inferred="true"} ! positive regulation of membrane invagination
 is_a: GO:2000431 {is_inferred="true"} ! regulation of cytokinesis, actomyosin contractile ring assembly
 
 [Term]
------------------------------------------------------------------------
r34598 | tberardi | 2016-07-26 16:06:17 -0700 (Tue, 26 Jul 2016) | 1 line

GH12556 update def cleavage furrow - closed

changes in entailments

------------------------------------------------------------------------
r34598 | tberardi | 2016-07-26 16:06:17 -0700 (Tue, 26 Jul 2016) | 1 line

GH12556 update def cleavage furrow - closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34598)
+++ go_inferences.obo	(working copy)
@@ -59525,6 +59525,14 @@
 is_a: GO:0098795 {is_inferred="true"} ! mRNA cleavage involved in gene silencing
 
 [Term]
+id: GO:0090688 ! cleavage furrow rim
+is_a: GO:0032155 {is_inferred="true"} ! cell division site part
+
+[Term]
+id: GO:0090689 ! cleavage furrow leading edge
+is_a: GO:0032155 {is_inferred="true"} ! cell division site part
+
+[Term]
 id: GO:0093001 ! glycolysis from storage polysaccharide through glucose-1-phosphate
 is_a: GO:0000272 {is_inferred="true"} ! polysaccharide catabolic process
 is_a: GO:0061622 {is_inferred="true"} ! glycolytic process through glucose-1-phosphate
------------------------------------------------------------------------
r34592 | mcourtot | 2016-07-26 01:15:43 -0700 (Tue, 26 Jul 2016) | 1 line

adding missing id: GO:0005515 to the metagenomics slim

changes in entailments

------------------------------------------------------------------------
r34587 | tberardi | 2016-07-25 16:18:21 -0700 (Mon, 25 Jul 2016) | 1 line

GH12545 part_of link for new term GO:1905324 - closed

changes in entailments

------------------------------------------------------------------------
r34550 | termgenie | 2016-07-22 09:24:42 -0700 (Fri, 22 Jul 2016) | 2 lines

TermGenie commit for user: als reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34550)
+++ go_inferences.obo	(working copy)
@@ -4542,6 +4542,7 @@
 is_a: GO:0010769 {is_inferred="true"} ! regulation of cell morphogenesis involved in differentiation
 is_a: GO:0030856 {is_inferred="true"} ! regulation of epithelial cell differentiation
 is_a: GO:0072215 {is_inferred="true"} ! regulation of metanephros development
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 is_a: GO:2000027 {is_inferred="true"} ! regulation of organ morphogenesis
 
 [Term]
@@ -4550,6 +4551,7 @@
 is_a: GO:0010771 {is_inferred="true"} ! negative regulation of cell morphogenesis involved in differentiation
 is_a: GO:0030857 {is_inferred="true"} ! negative regulation of epithelial cell differentiation
 is_a: GO:0072217 {is_inferred="true"} ! negative regulation of metanephros development
+is_a: GO:1905331 {is_inferred="true"} ! negative regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:0003348 ! cardiac endothelial cell differentiation
@@ -21237,16 +21239,19 @@
 [Term]
 id: GO:0030860 ! regulation of polarized epithelial cell differentiation
 is_a: GO:0030856 {is_inferred="true"} ! regulation of epithelial cell differentiation
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:0030861 ! negative regulation of polarized epithelial cell differentiation
 is_a: GO:0030857 {is_inferred="true"} ! negative regulation of epithelial cell differentiation
 is_a: GO:0030860 {is_inferred="true"} ! regulation of polarized epithelial cell differentiation
+is_a: GO:1905331 {is_inferred="true"} ! negative regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:0030862 ! positive regulation of polarized epithelial cell differentiation
 is_a: GO:0030858 {is_inferred="true"} ! positive regulation of epithelial cell differentiation
 is_a: GO:0030860 {is_inferred="true"} ! regulation of polarized epithelial cell differentiation
+is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:0030864 ! cortical actin cytoskeleton
@@ -48728,6 +48733,7 @@
 [Term]
 id: GO:0060514 ! prostate induction
 is_a: GO:0040019 {is_inferred="true"} ! positive regulation of embryonic development
+is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:0060515 ! prostate field specification
@@ -49079,6 +49085,7 @@
 id: GO:0060651 ! regulation of epithelial cell proliferation involved in mammary gland bud elongation
 is_a: GO:0033599 {is_inferred="true"} ! regulation of mammary gland epithelial cell proliferation
 is_a: GO:0048638 {is_inferred="true"} ! regulation of developmental growth
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:0060652 ! mammary gland cord morphogenesis
@@ -49168,6 +49175,7 @@
 is_a: GO:0003156 {is_inferred="true"} ! regulation of organ formation
 is_a: GO:0045995 {is_inferred="true"} ! regulation of embryonic development
 is_a: GO:0060688 {is_inferred="true"} ! regulation of morphogenesis of a branching structure
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
 
 [Term]
@@ -49174,11 +49182,13 @@
 id: GO:0060686 ! negative regulation of prostatic bud formation
 is_a: GO:0045992 {is_inferred="true"} ! negative regulation of embryonic development
 is_a: GO:0060685 {is_inferred="true"} ! regulation of prostatic bud formation
+is_a: GO:1905331 {is_inferred="true"} ! negative regulation of morphogenesis of an epithelium
 is_a: GO:2000242 {is_inferred="true"} ! negative regulation of reproductive process
 
 [Term]
 id: GO:0060687 ! regulation of branching involved in prostate gland morphogenesis
 is_a: GO:0060688 {is_inferred="true"} ! regulation of morphogenesis of a branching structure
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 is_a: GO:2000027 {is_inferred="true"} ! regulation of organ morphogenesis
 is_a: GO:2000241 {is_inferred="true"} ! regulation of reproductive process
 
@@ -49208,6 +49218,7 @@
 [Term]
 id: GO:0060693 ! regulation of branching involved in salivary gland morphogenesis
 is_a: GO:0060688 {is_inferred="true"} ! regulation of morphogenesis of a branching structure
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:0060694 ! regulation of cholesterol transporter activity
@@ -49459,6 +49470,7 @@
 [Term]
 id: GO:0060762 ! regulation of branching involved in mammary gland duct morphogenesis
 is_a: GO:0060688 {is_inferred="true"} ! regulation of morphogenesis of a branching structure
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:0060764 ! cell-cell signaling involved in mammary gland development
@@ -49533,6 +49545,7 @@
 [Term]
 id: GO:0060787 ! positive regulation of posterior neural plate formation by fibroblast growth factor receptor signaling pathway
 is_a: GO:0040019 {is_inferred="true"} ! positive regulation of embryonic development
+is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:0060795 ! cell fate commitment involved in formation of primary germ layer
@@ -49999,19 +50012,20 @@
 [Term]
 id: GO:0061046 ! regulation of branching involved in lung morphogenesis
 is_a: GO:0060688 {is_inferred="true"} ! regulation of morphogenesis of a branching structure
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 is_a: GO:2000027 {is_inferred="true"} ! regulation of organ morphogenesis
 
 [Term]
 id: GO:0061047 ! positive regulation of branching involved in lung morphogenesis
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:0061046 {is_inferred="true"} ! regulation of branching involved in lung morphogenesis
+is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:0061048 ! negative regulation of branching involved in lung morphogenesis
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:0061046 {is_inferred="true"} ! regulation of branching involved in lung morphogenesis
+is_a: GO:1905331 {is_inferred="true"} ! negative regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:0061050 ! regulation of cell growth involved in cardiac muscle cell development
@@ -55341,6 +55355,10 @@
 is_a: GO:0035295 {is_inferred="true"} ! tube development
 
 [Term]
+id: GO:0072034 ! renal vesicle induction
+is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
+
+[Term]
 id: GO:0072036 ! mesenchymal to epithelial transition involved in renal vesicle formation
 is_a: GO:0060231 {is_inferred="true"} ! mesenchymal to epithelial transition
 
@@ -55381,6 +55399,7 @@
 id: GO:0072043 ! regulation of pre-tubular aggregate formation by cell-cell signaling
 is_a: GO:0022407 {is_inferred="true"} ! regulation of cell-cell adhesion
 is_a: GO:0090183 {is_inferred="true"} ! regulation of kidney development
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 is_a: GO:2000027 {is_inferred="true"} ! regulation of organ morphogenesis
 
 [Term]
@@ -55493,6 +55512,7 @@
 is_a: GO:0010770 {is_inferred="true"} ! positive regulation of cell morphogenesis involved in differentiation
 is_a: GO:0030858 {is_inferred="true"} ! positive regulation of epithelial cell differentiation
 is_a: GO:0072216 {is_inferred="true"} ! positive regulation of metanephros development
+is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:0072111 ! cell proliferation involved in kidney development
@@ -57894,6 +57914,7 @@
 [Term]
 id: GO:0090021 ! positive regulation of posterior neural plate formation by Wnt signaling pathway
 is_a: GO:0040019 {is_inferred="true"} ! positive regulation of embryonic development
+is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:0090022 ! regulation of neutrophil chemotaxis
@@ -58350,6 +58371,10 @@
 is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
 [Term]
+id: GO:0090175 ! regulation of establishment of planar polarity
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
+
+[Term]
 id: GO:0090176 ! microtubule cytoskeleton organization involved in establishment of planar polarity
 is_a: GO:0000226 {is_inferred="true"} ! microtubule cytoskeleton organization
 
@@ -58412,16 +58437,19 @@
 id: GO:0090189 ! regulation of branching involved in ureteric bud morphogenesis
 is_a: GO:0060688 {is_inferred="true"} ! regulation of morphogenesis of a branching structure
 is_a: GO:0061217 {is_inferred="true"} ! regulation of mesonephros development
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:0090190 ! positive regulation of branching involved in ureteric bud morphogenesis
 is_a: GO:0061213 {is_inferred="true"} ! positive regulation of mesonephros development
 is_a: GO:0090189 {is_inferred="true"} ! regulation of branching involved in ureteric bud morphogenesis
+is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:0090191 ! negative regulation of branching involved in ureteric bud morphogenesis
 is_a: GO:0061218 {is_inferred="true"} ! negative regulation of mesonephros development
 is_a: GO:0090189 {is_inferred="true"} ! regulation of branching involved in ureteric bud morphogenesis
+is_a: GO:1905331 {is_inferred="true"} ! negative regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:0090192 ! regulation of glomerulus development
@@ -58691,6 +58719,7 @@
 id: GO:0090256 ! regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis
 is_a: GO:0042127 {is_inferred="true"} ! regulation of cell proliferation
 is_a: GO:0048580 {is_inferred="true"} ! regulation of post-embryonic development
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 is_a: GO:2000027 {is_inferred="true"} ! regulation of organ morphogenesis
 
 [Term]
@@ -68681,6 +68710,7 @@
 [Term]
 id: GO:1901207 ! regulation of heart looping
 is_a: GO:0045995 {is_inferred="true"} ! regulation of embryonic development
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 is_a: GO:2000826 {is_inferred="true"} ! regulation of heart morphogenesis
 
 [Term]
@@ -68687,11 +68717,13 @@
 id: GO:1901208 ! negative regulation of heart looping
 is_a: GO:0045992 {is_inferred="true"} ! negative regulation of embryonic development
 is_a: GO:1901207 {is_inferred="true"} ! regulation of heart looping
+is_a: GO:1905331 {is_inferred="true"} ! negative regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:1901209 ! positive regulation of heart looping
 is_a: GO:0040019 {is_inferred="true"} ! positive regulation of embryonic development
 is_a: GO:1901207 {is_inferred="true"} ! regulation of heart looping
+is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:1901210 ! regulation of cardiac chamber formation
@@ -68795,18 +68827,20 @@
 
 [Term]
 id: GO:1901232 ! regulation of convergent extension involved in axis elongation
-is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
 is_a: GO:0048638 {is_inferred="true"} ! regulation of developmental growth
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:1901233 ! negative regulation of convergent extension involved in axis elongation
 is_a: GO:0048640 {is_inferred="true"} ! negative regulation of developmental growth
 is_a: GO:1901232 {is_inferred="true"} ! regulation of convergent extension involved in axis elongation
+is_a: GO:1905331 {is_inferred="true"} ! negative regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:1901234 ! positive regulation of convergent extension involved in axis elongation
 is_a: GO:0048639 {is_inferred="true"} ! positive regulation of developmental growth
 is_a: GO:1901232 {is_inferred="true"} ! regulation of convergent extension involved in axis elongation
+is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:1901235 ! (R)-carnitine transmembrane transporter activity
@@ -70149,7 +70183,7 @@
 
 [Term]
 id: GO:1901509 ! regulation of endothelial tube morphogenesis
-is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
 
 [Term]
@@ -80811,23 +80845,23 @@
 
 [Term]
 id: GO:1903689 ! regulation of wound healing, spreading of epidermal cells
-is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
 is_a: GO:0030334 {is_inferred="true"} ! regulation of cell migration
 is_a: GO:0061041 {is_inferred="true"} ! regulation of wound healing
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:1903690 ! negative regulation of wound healing, spreading of epidermal cells
 is_a: GO:0030336 {is_inferred="true"} ! negative regulation of cell migration
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0061045 {is_inferred="true"} ! negative regulation of wound healing
 is_a: GO:1903689 {is_inferred="true"} ! regulation of wound healing, spreading of epidermal cells
+is_a: GO:1905331 {is_inferred="true"} ! negative regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:1903691 ! positive regulation of wound healing, spreading of epidermal cells
 is_a: GO:0030335 {is_inferred="true"} ! positive regulation of cell migration
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0090303 {is_inferred="true"} ! positive regulation of wound healing
 is_a: GO:1903689 {is_inferred="true"} ! regulation of wound healing, spreading of epidermal cells
+is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:1903692 ! methionine import into cell
@@ -82706,15 +82740,18 @@
 [Term]
 id: GO:1904086 ! regulation of epiboly involved in gastrulation with mouth forming second
 is_a: GO:0010470 {is_inferred="true"} ! regulation of gastrulation
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:1904087 ! negative regulation of epiboly involved in gastrulation with mouth forming second
 is_a: GO:1904086 {is_inferred="true"} ! regulation of epiboly involved in gastrulation with mouth forming second
+is_a: GO:1905331 {is_inferred="true"} ! negative regulation of morphogenesis of an epithelium
 is_a: GO:2000542 {is_inferred="true"} ! negative regulation of gastrulation
 
 [Term]
 id: GO:1904088 ! positive regulation of epiboly involved in gastrulation with mouth forming second
 is_a: GO:1904086 {is_inferred="true"} ! regulation of epiboly involved in gastrulation with mouth forming second
+is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
 is_a: GO:2000543 {is_inferred="true"} ! positive regulation of gastrulation
 
 [Term]
@@ -82788,15 +82825,18 @@
 [Term]
 id: GO:1904103 ! regulation of convergent extension involved in gastrulation
 is_a: GO:0010470 {is_inferred="true"} ! regulation of gastrulation
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:1904104 ! negative regulation of convergent extension involved in gastrulation
 is_a: GO:1904103 {is_inferred="true"} ! regulation of convergent extension involved in gastrulation
+is_a: GO:1905331 {is_inferred="true"} ! negative regulation of morphogenesis of an epithelium
 is_a: GO:2000542 {is_inferred="true"} ! negative regulation of gastrulation
 
 [Term]
 id: GO:1904105 ! positive regulation of convergent extension involved in gastrulation
 is_a: GO:1904103 {is_inferred="true"} ! regulation of convergent extension involved in gastrulation
+is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
 is_a: GO:2000543 {is_inferred="true"} ! positive regulation of gastrulation
 
 [Term]
@@ -82862,6 +82902,7 @@
 [Term]
 id: GO:1904118 ! regulation of otic vesicle morphogenesis
 is_a: GO:0045995 {is_inferred="true"} ! regulation of embryonic development
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 is_a: GO:2000027 {is_inferred="true"} ! regulation of organ morphogenesis
 
 [Term]
@@ -82868,11 +82909,13 @@
 id: GO:1904119 ! negative regulation of otic vesicle morphogenesis
 is_a: GO:0045992 {is_inferred="true"} ! negative regulation of embryonic development
 is_a: GO:1904118 {is_inferred="true"} ! regulation of otic vesicle morphogenesis
+is_a: GO:1905331 {is_inferred="true"} ! negative regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:1904120 ! positive regulation of otic vesicle morphogenesis
 is_a: GO:0040019 {is_inferred="true"} ! positive regulation of embryonic development
 is_a: GO:1904118 {is_inferred="true"} ! regulation of otic vesicle morphogenesis
+is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:1904121 ! phosphatidylethanolamine transporter activity
@@ -88537,20 +88580,20 @@
 
 [Term]
 id: GO:1905276 ! regulation of epithelial tube formation
-is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
 
 [Term]
 id: GO:1905277 ! negative regulation of epithelial tube formation
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
 is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:1905276 {is_inferred="true"} ! regulation of epithelial tube formation
+is_a: GO:1905331 {is_inferred="true"} ! negative regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:1905278 ! positive regulation of epithelial tube formation
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
 is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:1905276 {is_inferred="true"} ! regulation of epithelial tube formation
+is_a: GO:1905332 {is_inferred="true"} ! positive regulation of morphogenesis of an epithelium
 
 [Term]
 id: GO:1905279 ! regulation of retrograde transport, endosome to Golgi
@@ -88831,6 +88874,24 @@
 is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
 
 [Term]
+id: GO:1905330 ! regulation of morphogenesis of an epithelium
+is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
+
+[Term]
+id: GO:1905331 ! negative regulation of morphogenesis of an epithelium
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
+
+[Term]
+id: GO:1905332 ! positive regulation of morphogenesis of an epithelium
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
+
+[Term]
+id: GO:1905333 ! regulation of gastric motility
+is_a: GO:0044058 {is_inferred="true"} ! regulation of digestive system process
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
@@ -90642,6 +90703,7 @@
 [Term]
 id: GO:2000166 ! negative regulation of planar cell polarity pathway involved in pericardium morphogenesis
 is_a: GO:0045992 {is_inferred="true"} ! negative regulation of embryonic development
+is_a: GO:1905331 {is_inferred="true"} ! negative regulation of morphogenesis of an epithelium
 is_a: GO:2000160 {is_inferred="true"} ! negative regulation of planar cell polarity pathway involved in heart morphogenesis
 is_a: GO:2000165 {is_inferred="true"} ! regulation of planar cell polarity pathway involved in pericardium morphogenesis
 
@@ -90937,6 +90999,7 @@
 id: GO:2000223 ! regulation of BMP signaling pathway involved in heart jogging
 is_a: GO:0030510 {is_inferred="true"} ! regulation of BMP signaling pathway
 is_a: GO:0045995 {is_inferred="true"} ! regulation of embryonic development
+is_a: GO:1905330 {is_inferred="true"} ! regulation of morphogenesis of an epithelium
 is_a: GO:2000826 {is_inferred="true"} ! regulation of heart morphogenesis
 
 [Term]
------------------------------------------------------------------------
r34542 | termgenie | 2016-07-21 18:46:09 -0700 (Thu, 21 Jul 2016) | 2 lines

TermGenie commit for user: tb reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34542)
+++ go_inferences.obo	(working copy)
@@ -88826,6 +88826,11 @@
 is_a: GO:0048856 {is_inferred="true"} ! anatomical structure development
 
 [Term]
+id: GO:1905329 ! sphingoid long-chain base transport
+is_a: GO:0015695 {is_inferred="true"} ! organic cation transport
+is_a: GO:0015696 {is_inferred="true"} ! ammonium transport
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34533 | termgenie | 2016-07-21 11:28:48 -0700 (Thu, 21 Jul 2016) | 2 lines

TermGenie commit for user: tb reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34534)
+++ go_inferences.obo	(working copy)
@@ -57403,11 +57403,20 @@
 is_a: GO:0015211 {is_inferred="true"} ! purine nucleoside transmembrane transporter activity
 
 [Term]
+id: GO:0080126 ! ovary septum development
+is_a: GO:1905328 {is_inferred="true"} ! plant septum development
+
+[Term]
 id: GO:0080127 ! fruit septum development
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
+is_a: GO:1905328 {is_inferred="true"} ! plant septum development
 
 [Term]
+id: GO:0080128 ! anther septum development
+is_a: GO:1905328 {is_inferred="true"} ! plant septum development
+
+[Term]
 id: GO:0080134 ! regulation of response to stress
 is_a: GO:0048583 {is_inferred="true"} ! regulation of response to stimulus
 
@@ -88813,6 +88822,10 @@
 is_a: GO:0048646 {is_inferred="true"} ! anatomical structure formation involved in morphogenesis
 
 [Term]
+id: GO:1905328 ! plant septum development
+is_a: GO:0048856 {is_inferred="true"} ! anatomical structure development
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34532 | termgenie | 2016-07-21 11:21:10 -0700 (Thu, 21 Jul 2016) | 2 lines

TermGenie commit for user: tb reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34532)
+++ go_inferences.obo	(working copy)
@@ -88809,6 +88809,10 @@
 is_a: GO:1905325 {is_inferred="true"} ! regulation of meiosis I spindle assembly checkpoint
 
 [Term]
+id: GO:1905327 ! tracheoesophageal septum formation
+is_a: GO:0048646 {is_inferred="true"} ! anatomical structure formation involved in morphogenesis
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34530 | mcourtot | 2016-07-21 07:50:24 -0700 (Thu, 21 Jul 2016) | 1 line

added new metagenomics slim terms

changes in entailments

------------------------------------------------------------------------
r34528 | mcourtot | 2016-07-21 07:34:17 -0700 (Thu, 21 Jul 2016) | 1 line

remove old metagenomics slim terms

changes in entailments

------------------------------------------------------------------------
r34526 | davidos | 2016-07-21 06:15:42 -0700 (Thu, 21 Jul 2016) | 14 lines

Fixes: #12547; #12510;  #12508; #12429; #12505 (+related refactoring

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34526)
+++ go_inferences.obo	(working copy)
@@ -4190,10 +4190,6 @@
 is_a: GO:0098801 {is_inferred="true"} ! regulation of renal system process
 
 [Term]
-id: GO:0003096 ! renal sodium ion transport
-is_a: GO:0044707 {is_inferred="true"} ! single-multicellular organism process
-
-[Term]
 id: GO:0003097 ! renal water transport
 is_a: GO:0044707 {is_inferred="true"} ! single-multicellular organism process
 
@@ -5115,7 +5111,6 @@
 [Term]
 id: GO:0005589 ! collagen type VI trimer
 is_a: GO:0044420 {is_inferred="true"} ! extracellular matrix component
-is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
 
 [Term]
 id: GO:0005591 ! collagen type VIII trimer
@@ -5131,14 +5126,6 @@
 is_a: GO:0030936 {is_inferred="true"} ! transmembrane collagen trimer
 
 [Term]
-id: GO:0005604 ! basement membrane
-is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
-
-[Term]
-id: GO:0005605 ! basal lamina
-is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
-
-[Term]
 id: GO:0005628 ! prospore membrane
 is_a: GO:0044464 {is_inferred="true"} ! cell part
 
@@ -5320,6 +5307,11 @@
 is_a: GO:1990234 {is_inferred="true"} ! transferase complex
 
 [Term]
+id: GO:0005788 ! endoplasmic reticulum lumen
+is_a: GO:0044432 {is_inferred="true"} ! endoplasmic reticulum part
+is_a: GO:0070013 {is_inferred="true"} ! intracellular organelle lumen
+
+[Term]
 id: GO:0005789 ! endoplasmic reticulum membrane
 is_a: GO:0016020 {is_inferred="true"} ! membrane
 is_a: GO:0044425 {is_inferred="true"} ! membrane part
@@ -5338,6 +5330,10 @@
 is_a: GO:0005876 {is_inferred="true"} ! spindle microtubule
 
 [Term]
+id: GO:0005829 ! cytosol
+is_a: GO:0044444 {is_inferred="true"} ! cytoplasmic part
+
+[Term]
 id: GO:0005834 ! heterotrimeric G-protein complex
 is_a: GO:0044424 {is_inferred="true"} ! intracellular part
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
@@ -7853,6 +7849,10 @@
 is_a: GO:1903409 {is_inferred="true"} ! reactive oxygen species biosynthetic process
 
 [Term]
+id: GO:0006811 ! ion transport
+is_a: GO:0006810 {is_inferred="true"} ! transport
+
+[Term]
 id: GO:0006812 ! cation transport
 is_a: GO:0006811 {is_inferred="true"} ! ion transport
 
@@ -8672,18 +8672,6 @@
 is_a: GO:0019098 {is_inferred="true"} ! reproductive behavior
 
 [Term]
-id: GO:0008002 ! lamina lucida
-is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
-
-[Term]
-id: GO:0008003 ! lamina densa
-is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
-
-[Term]
-id: GO:0008004 ! lamina reticularis
-is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
-
-[Term]
 id: GO:0008016 ! regulation of heart contraction
 is_a: GO:1903522 {is_inferred="true"} ! regulation of blood circulation
 
@@ -14268,6 +14256,14 @@
 is_a: GO:0098827 {is_inferred="true"} ! endoplasmic reticulum subcompartment
 
 [Term]
+id: GO:0014803 ! longitudinal sarcoplasmic reticulum lumen
+is_a: GO:0033018 {is_inferred="true"} ! sarcoplasmic reticulum lumen
+
+[Term]
+id: GO:0014804 ! terminal cisterna lumen
+is_a: GO:0033018 {is_inferred="true"} ! sarcoplasmic reticulum lumen
+
+[Term]
 id: GO:0014806 ! smooth muscle hyperplasia
 is_a: GO:0014900 {is_inferred="true"} ! muscle hyperplasia
 
@@ -15217,7 +15213,7 @@
 [Term]
 id: GO:0015680 ! intracellular copper ion transport
 is_a: GO:0006825 {is_inferred="true"} ! copper ion transport
-is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
+is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
 
 [Term]
 id: GO:0015682 ! ferric iron transport
@@ -16444,7 +16440,7 @@
 
 [Term]
 id: GO:0016079 ! synaptic vesicle exocytosis
-is_a: GO:0099003 {is_inferred="true"} ! vesicle mediated transport in synapse
+is_a: GO:0099003 {is_inferred="true"} ! vesicle-mediated transport in synapse
 is_a: GO:0099531 {is_inferred="true"} ! presynaptic process involved in chemical synaptic transmission
 is_a: GO:0099643 {is_inferred="true"} ! signal release from synapse
 
@@ -16738,7 +16734,7 @@
 id: GO:0016182 ! synaptic vesicle budding from endosome
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
 is_a: GO:0070142 {is_inferred="true"} ! synaptic vesicle budding
-is_a: GO:0099003 {is_inferred="true"} ! vesicle mediated transport in synapse
+is_a: GO:0099003 {is_inferred="true"} ! vesicle-mediated transport in synapse
 
 [Term]
 id: GO:0016185 ! synaptic vesicle budding from presynaptic endocytic zone membrane
@@ -21469,6 +21465,10 @@
 is_a: GO:0044435 {is_inferred="true"} ! plastid part
 
 [Term]
+id: GO:0031012 ! extracellular matrix
+is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
+
+[Term]
 id: GO:0031017 ! exocrine pancreas development
 is_a: GO:0048732 {is_inferred="true"} ! gland development
 
@@ -23008,6 +23008,10 @@
 is_a: GO:0098805 {is_inferred="true"} ! whole membrane
 
 [Term]
+id: GO:0031970 ! organelle envelope lumen
+is_a: GO:0070013 {is_inferred="true"} ! intracellular organelle lumen
+
+[Term]
 id: GO:0031976 ! plastid thylakoid
 is_a: GO:0009579 {is_inferred="true"} ! thylakoid
 is_a: GO:0044435 {is_inferred="true"} ! plastid part
@@ -24523,10 +24527,6 @@
 is_a: GO:0098805 {is_inferred="true"} ! whole membrane
 
 [Term]
-id: GO:0032579 ! apical lamina of hyaline layer
-is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
-
-[Term]
 id: GO:0032580 ! Golgi cisterna membrane
 is_a: GO:0000139 {is_inferred="true"} ! Golgi membrane
 
@@ -25827,7 +25827,7 @@
 [Term]
 id: GO:0032975 ! amino acid transmembrane import into vacuole
 is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
-is_a: GO:0043090 {is_inferred="true"} ! amino acid import
+is_a: GO:0044745 {is_inferred="true"} ! amino acid transmembrane import
 
 [Term]
 id: GO:0032981 ! mitochondrial respiratory chain complex I assembly
@@ -25935,6 +25935,10 @@
 is_a: GO:0098588 {is_inferred="true"} ! bounding membrane of organelle
 
 [Term]
+id: GO:0033018 ! sarcoplasmic reticulum lumen
+is_a: GO:0005788 {is_inferred="true"} ! endoplasmic reticulum lumen
+
+[Term]
 id: GO:0033020 ! cyclopentanol metabolic process
 is_a: GO:0006066 {is_inferred="true"} ! alcohol metabolic process
 is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
@@ -28540,10 +28544,14 @@
 
 [Term]
 id: GO:0034488 ! basic amino acid transmembrane export from vacuole
+is_a: GO:0015802 {is_inferred="true"} ! basic amino acid transport
+is_a: GO:0032974 {is_inferred="true"} ! amino acid transmembrane export from vacuole
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
 id: GO:0034489 ! neutral amino acid transmembrane export from vacuole
+is_a: GO:0015804 {is_inferred="true"} ! neutral amino acid transport
+is_a: GO:0032974 {is_inferred="true"} ! amino acid transmembrane export from vacuole
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
@@ -28812,19 +28820,16 @@
 
 [Term]
 id: GO:0034762 ! regulation of transmembrane transport
-is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
 is_a: GO:0051049 {is_inferred="true"} ! regulation of transport
 
 [Term]
 id: GO:0034763 ! negative regulation of transmembrane transport
 is_a: GO:0034762 {is_inferred="true"} ! regulation of transmembrane transport
-is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
 is_a: GO:0051051 {is_inferred="true"} ! negative regulation of transport
 
 [Term]
 id: GO:0034764 ! positive regulation of transmembrane transport
 is_a: GO:0034762 {is_inferred="true"} ! regulation of transmembrane transport
-is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
 is_a: GO:0051050 {is_inferred="true"} ! positive regulation of transport
 
 [Term]
@@ -30015,10 +30020,6 @@
 is_a: GO:0015077 {is_inferred="true"} ! monovalent inorganic cation transmembrane transporter activity
 
 [Term]
-id: GO:0035828 ! renal rubidium ion transport
-is_a: GO:0044707 {is_inferred="true"} ! single-multicellular organism process
-
-[Term]
 id: GO:0035830 ! palmatine metabolic process
 is_a: GO:0033076 {is_inferred="true"} ! isoquinoline alkaloid metabolic process
 
@@ -30781,7 +30782,7 @@
 
 [Term]
 id: GO:0036465 ! synaptic vesicle recycling
-is_a: GO:0099003 {is_inferred="true"} ! vesicle mediated transport in synapse
+is_a: GO:0099003 {is_inferred="true"} ! vesicle-mediated transport in synapse
 
 [Term]
 id: GO:0036502 ! Derlin-1-VIMP complex
@@ -33771,10 +33772,6 @@
 is_a: GO:0043200 {is_inferred="true"} ! response to amino acid
 
 [Term]
-id: GO:0043205 ! fibril
-is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
-
-[Term]
 id: GO:0043208 ! glycosphingolipid binding
 is_a: GO:0046625 {is_inferred="true"} ! sphingolipid binding
 is_a: GO:0051861 {is_inferred="true"} ! glycolipid binding
@@ -33807,6 +33804,11 @@
 is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
 
 [Term]
+id: GO:0043233 ! organelle lumen
+is_a: GO:0031974 {is_inferred="true"} ! membrane-enclosed lumen
+is_a: GO:0044422 {is_inferred="true"} ! organelle part
+
+[Term]
 id: GO:0043241 ! protein complex disassembly
 is_a: GO:0032984 {is_inferred="true"} ! macromolecular complex disassembly
 
@@ -33840,10 +33842,6 @@
 is_a: GO:0009889 {is_inferred="true"} ! regulation of biosynthetic process
 
 [Term]
-id: GO:0043256 ! laminin complex
-is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
-
-[Term]
 id: GO:0043266 ! regulation of potassium ion transport
 is_a: GO:0010959 {is_inferred="true"} ! regulation of metal ion transport
 
@@ -35383,7 +35381,7 @@
 
 [Term]
 id: GO:0044420 ! extracellular matrix component
-is_a: GO:0005575 {is_inferred="true"} ! cellular_component
+is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
 
 [Term]
 id: GO:0044421 ! extracellular region part
@@ -35676,6 +35674,10 @@
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
 [Term]
+id: GO:0044743 ! intracellular protein transmembrane import
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
+
+[Term]
 id: GO:0044744 ! protein targeting to nucleus
 is_a: GO:0034504 {is_inferred="true"} ! protein localization to nucleus
 is_a: GO:0051169 {is_inferred="true"} ! nuclear transport
@@ -35682,6 +35684,11 @@
 is_a: GO:0072594 {is_inferred="true"} ! establishment of protein localization to organelle
 
 [Term]
+id: GO:0044745 ! amino acid transmembrane import
+is_a: GO:0003333 {is_inferred="true"} ! amino acid transmembrane transport
+is_a: GO:0043090 {is_inferred="true"} ! amino acid import
+
+[Term]
 id: GO:0044746 ! amino acid transmembrane export
 is_a: GO:0003333 {is_inferred="true"} ! amino acid transmembrane transport
 is_a: GO:0032973 {is_inferred="true"} ! amino acid export
@@ -35821,6 +35828,7 @@
 [Term]
 id: GO:0044842 ! gut granule lumen
 is_a: GO:0044433 {is_inferred="true"} ! cytoplasmic vesicle part
+is_a: GO:0070013 {is_inferred="true"} ! intracellular organelle lumen
 
 [Term]
 id: GO:0044853 ! plasma membrane raft
@@ -42381,6 +42389,15 @@
 is_a: GO:0048856 {is_inferred="true"} ! anatomical structure development
 
 [Term]
+id: GO:0048237 ! rough endoplasmic reticulum lumen
+is_a: GO:0005788 {is_inferred="true"} ! endoplasmic reticulum lumen
+
+[Term]
+id: GO:0048238 ! smooth endoplasmic reticulum lumen
+is_a: GO:0005788 {is_inferred="true"} ! endoplasmic reticulum lumen
+is_a: GO:0097425 {is_inferred="true"} ! smooth endoplasmic reticulum part
+
+[Term]
 id: GO:0048240 ! sperm capacitation
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 
@@ -42798,7 +42815,7 @@
 [Term]
 id: GO:0048488 ! synaptic vesicle endocytosis
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
-is_a: GO:0099003 {is_inferred="true"} ! vesicle mediated transport in synapse
+is_a: GO:0099003 {is_inferred="true"} ! vesicle-mediated transport in synapse
 
 [Term]
 id: GO:0048489 ! synaptic vesicle transport
@@ -47490,6 +47507,10 @@
 is_a: GO:0098771 {is_inferred="true"} ! inorganic ion homeostasis
 
 [Term]
+id: GO:0055085 ! transmembrane transport
+is_a: GO:0006810 {is_inferred="true"} ! transport
+
+[Term]
 id: GO:0055086 ! nucleobase-containing small molecule metabolic process
 is_a: GO:0044763 {is_inferred="true"} ! single-organism cellular process
 
@@ -47719,7 +47740,6 @@
 [Term]
 id: GO:0060103 ! collagen and cuticulin-based cuticle extracellular matrix part
 is_a: GO:0044420 {is_inferred="true"} ! extracellular matrix component
-is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
 
 [Term]
 id: GO:0060114 ! vestibular receptor cell differentiation
@@ -47884,6 +47904,10 @@
 is_a: GO:0060194 {is_inferred="true"} ! regulation of antisense RNA transcription
 
 [Term]
+id: GO:0060205 ! cytoplasmic membrane-bounded vesicle lumen
+is_a: GO:0070013 {is_inferred="true"} ! intracellular organelle lumen
+
+[Term]
 id: GO:0060211 ! regulation of nuclear-transcribed mRNA poly(A) tail shortening
 is_a: GO:1900151 {is_inferred="true"} ! regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
 
@@ -48443,6 +48467,7 @@
 
 [Term]
 id: GO:0060402 ! calcium ion transport into cytosol
+is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
 
 [Term]
@@ -50931,10 +50956,6 @@
 is_a: GO:0098800 {is_inferred="true"} ! inner mitochondrial membrane protein complex
 
 [Term]
-id: GO:0061618 ! sublamina densa
-is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
-
-[Term]
 id: GO:0061619 ! glycolytic process from mannose through fructose-6-phosphate
 is_a: GO:0006002 {is_inferred="true"} ! fructose 6-phosphate metabolic process
 is_a: GO:0019309 {is_inferred="true"} ! mannose catabolic process
@@ -51095,7 +51116,6 @@
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
-is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:0065003 ! macromolecular complex assembly
@@ -51114,6 +51134,11 @@
 is_a: GO:0065007 {is_inferred="true"} ! biological regulation
 
 [Term]
+id: GO:0070013 ! intracellular organelle lumen
+is_a: GO:0043233 {is_inferred="true"} ! organelle lumen
+is_a: GO:0044424 {is_inferred="true"} ! intracellular part
+
+[Term]
 id: GO:0070014 ! sucrase-isomaltase complex
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 is_a: GO:1902687 {is_inferred="true"} ! glucosidase complex
@@ -54283,6 +54308,7 @@
 
 [Term]
 id: GO:0071423 ! malate transmembrane transport
+is_a: GO:0015743 {is_inferred="true"} ! malate transport
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
@@ -54933,6 +54959,10 @@
 is_a: GO:1902117 {is_inferred="true"} ! positive regulation of organelle assembly
 
 [Term]
+id: GO:0071804 ! cellular potassium ion transport
+is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
+
+[Term]
 id: GO:0071805 ! potassium ion transmembrane transport
 is_a: GO:0098662 {is_inferred="true"} ! inorganic cation transmembrane transport
 
@@ -57781,7 +57811,7 @@
 
 [Term]
 id: GO:0089718 ! amino acid import across plasma membrane
-is_a: GO:0003333 {is_inferred="true"} ! amino acid transmembrane transport
+is_a: GO:0044745 {is_inferred="true"} ! amino acid transmembrane import
 is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
 is_a: GO:1902837 {is_inferred="true"} ! amino acid import into cell
 
@@ -59164,7 +59194,7 @@
 
 [Term]
 id: GO:0090374 ! oligopeptide export from mitochondrion
-is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
+is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
@@ -59457,10 +59487,6 @@
 is_a: GO:0098795 {is_inferred="true"} ! mRNA cleavage involved in gene silencing
 
 [Term]
-id: GO:0090658 ! cone matrix sheath
-is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
-
-[Term]
 id: GO:0093001 ! glycolysis from storage polysaccharide through glucose-1-phosphate
 is_a: GO:0000272 {is_inferred="true"} ! polysaccharide catabolic process
 is_a: GO:0061622 {is_inferred="true"} ! glycolytic process through glucose-1-phosphate
@@ -60459,12 +60485,10 @@
 [Term]
 id: GO:0098642 ! network-forming collagen trimer
 is_a: GO:0044420 {is_inferred="true"} ! extracellular matrix component
-is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
 
 [Term]
 id: GO:0098644 ! complex of collagen trimers
 is_a: GO:0044420 {is_inferred="true"} ! extracellular matrix component
-is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
 
 [Term]
 id: GO:0098649 ! response to peptidyl-dipeptidase A inhibitor
@@ -60473,7 +60497,6 @@
 [Term]
 id: GO:0098651 ! basement membrane collagen trimer
 is_a: GO:0044420 {is_inferred="true"} ! extracellular matrix component
-is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
 
 [Term]
 id: GO:0098655 ! cation transmembrane transport
@@ -60486,6 +60509,10 @@
 is_a: GO:0034220 {is_inferred="true"} ! ion transmembrane transport
 
 [Term]
+id: GO:0098657 ! import into cell
+is_a: GO:0006810 {is_inferred="true"} ! transport
+
+[Term]
 id: GO:0098658 ! inorganic anion import into cell
 is_a: GO:0099587 {is_inferred="true"} ! inorganic ion import into cell
 
@@ -61000,13 +61027,13 @@
 [Term]
 id: GO:0098884 ! postsynaptic neurotransmitter receptor internalization
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
-is_a: GO:0099003 {is_inferred="true"} ! vesicle mediated transport in synapse
+is_a: GO:0099003 {is_inferred="true"} ! vesicle-mediated transport in synapse
 
 [Term]
 id: GO:0098887 ! neurotransmitter receptor transport, endosome to postsynaptic membrane
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
 is_a: GO:0098969 {is_inferred="true"} ! neurotransmitter receptor transport to postsynaptic membrane
-is_a: GO:0099003 {is_inferred="true"} ! vesicle mediated transport in synapse
+is_a: GO:0099003 {is_inferred="true"} ! vesicle-mediated transport in synapse
 is_a: GO:0099639 {is_inferred="true"} ! neurotransmitter receptor transport, endosome to plasma membrane
 
 [Term]
@@ -61479,6 +61506,23 @@
 is_a: GO:0061109 {is_inferred="true"} ! dense core granule organization
 
 [Term]
+id: GO:0099017 ! maintenance of protein localization at cell tip
+is_a: GO:0032507 {is_inferred="true"} ! maintenance of protein location in cell
+
+[Term]
+id: GO:0099019 ! maintenance of protein localization at growing cell tip
+is_a: GO:0099017 {is_inferred="true"} ! maintenance of protein localization at cell tip
+
+[Term]
+id: GO:0099020 ! perinuclear endoplasmic reticulum lumen
+is_a: GO:0005788 {is_inferred="true"} ! endoplasmic reticulum lumen
+
+[Term]
+id: GO:0099021 ! cortical endoplasmic reticulum lumen
+is_a: GO:0005788 {is_inferred="true"} ! endoplasmic reticulum lumen
+is_a: GO:0044448 {is_inferred="true"} ! cell cortex part
+
+[Term]
 id: GO:0099025 ! anchored component of postsynaptic membrane
 is_a: GO:0046658 {is_inferred="true"} ! anchored component of plasma membrane
 is_a: GO:0098936 {is_inferred="true"} ! intrinsic component of postsynaptic membrane
@@ -61691,7 +61735,7 @@
 [Term]
 id: GO:0099525 ! presynaptic dense core vesicle exocytosis
 is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
-is_a: GO:0099003 {is_inferred="true"} ! vesicle mediated transport in synapse
+is_a: GO:0099003 {is_inferred="true"} ! vesicle-mediated transport in synapse
 is_a: GO:0099011 {is_inferred="true"} ! neuronal dense core vesicle exocytosis
 is_a: GO:0099643 {is_inferred="true"} ! signal release from synapse
 
@@ -69462,11 +69506,13 @@
 [Term]
 id: GO:1901379 ! regulation of potassium ion transmembrane transport
 is_a: GO:0043266 {is_inferred="true"} ! regulation of potassium ion transport
+is_a: GO:0050794 {is_inferred="true"} ! regulation of cellular process
 is_a: GO:1904062 {is_inferred="true"} ! regulation of cation transmembrane transport
 
 [Term]
 id: GO:1901380 ! negative regulation of potassium ion transmembrane transport
 is_a: GO:0043267 {is_inferred="true"} ! negative regulation of potassium ion transport
+is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
 is_a: GO:1901379 {is_inferred="true"} ! regulation of potassium ion transmembrane transport
 is_a: GO:1904063 {is_inferred="true"} ! negative regulation of cation transmembrane transport
 
@@ -69473,6 +69519,7 @@
 [Term]
 id: GO:1901381 ! positive regulation of potassium ion transmembrane transport
 is_a: GO:0043268 {is_inferred="true"} ! positive regulation of potassium ion transport
+is_a: GO:0048522 {is_inferred="true"} ! positive regulation of cellular process
 is_a: GO:1901379 {is_inferred="true"} ! regulation of potassium ion transmembrane transport
 is_a: GO:1904064 {is_inferred="true"} ! positive regulation of cation transmembrane transport
 
@@ -85803,8 +85850,8 @@
 
 [Term]
 id: GO:1904724 ! tertiary granule lumen
-is_a: GO:0031974 {is_inferred="true"} ! membrane-enclosed lumen
 is_a: GO:0044433 {is_inferred="true"} ! cytoplasmic vesicle part
+is_a: GO:0070013 {is_inferred="true"} ! intracellular organelle lumen
 
 [Term]
 id: GO:1904725 ! TFIIB-class transcription factor binding involved in negative regulation of transcription
@@ -86223,8 +86270,8 @@
 
 [Term]
 id: GO:1904813 ! ficolin-1-rich granule lumen
-is_a: GO:0031974 {is_inferred="true"} ! membrane-enclosed lumen
 is_a: GO:0044433 {is_inferred="true"} ! cytoplasmic vesicle part
+is_a: GO:0070013 {is_inferred="true"} ! intracellular organelle lumen
 
 [Term]
 id: GO:1904814 ! regulation of protein localization to chromosome, telomeric region
@@ -88788,9 +88835,9 @@
 
 [Term]
 id: GO:1990036 ! calcium ion import into sarcoplasmic reticulum
+is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
 is_a: GO:0070296 {is_inferred="true"} ! sarcoplasmic reticulum calcium ion transport
 is_a: GO:0070509 {is_inferred="true"} ! calcium ion import
-is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:1990037 ! Lewy body core
@@ -88898,6 +88945,7 @@
 
 [Term]
 id: GO:1990122 ! leucine import into cell
+is_a: GO:0060356 {is_inferred="true"} ! leucine import
 is_a: GO:1902837 {is_inferred="true"} ! amino acid import into cell
 
 [Term]
@@ -89418,6 +89466,7 @@
 [Term]
 id: GO:1990591 ! asparagine transmembrane import into vacuole
 is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
+is_a: GO:0044745 {is_inferred="true"} ! amino acid transmembrane import
 is_a: GO:0090469 {is_inferred="true"} ! asparagine import
 is_a: GO:1903713 {is_inferred="true"} ! asparagine transmembrane transport
 
------------------------------------------------------------------------
r34519 | tberardi | 2016-07-20 16:51:09 -0700 (Wed, 20 Jul 2016) | 1 line

GH12551 activation of meiosis I spindle assembly checkpoint - closed

changes in entailments

------------------------------------------------------------------------
r34517 | tberardi | 2016-07-20 16:38:53 -0700 (Wed, 20 Jul 2016) | 1 line

GH12497 glycine betaine-activated nonselective monovalent cation channel activity - closed

changes in entailments

------------------------------------------------------------------------
r34515 | tberardi | 2016-07-20 16:25:42 -0700 (Wed, 20 Jul 2016) | 1 line

GH12493 synonyms for R-SMADs - closed

changes in entailments

------------------------------------------------------------------------
r34513 | termgenie | 2016-07-20 15:43:27 -0700 (Wed, 20 Jul 2016) | 3 lines

TermGenie commit for user: mah reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34513)
+++ go_inferences.obo	(working copy)
@@ -88750,6 +88750,18 @@
 is_a: GO:0065004 {is_inferred="true"} ! protein-DNA complex assembly
 
 [Term]
+id: GO:1905325 ! regulation of meiosis I spindle assembly checkpoint
+is_a: GO:0060631 {is_inferred="true"} ! regulation of meiosis I
+is_a: GO:0090231 {is_inferred="true"} ! regulation of spindle checkpoint
+is_a: GO:1902102 {is_inferred="true"} ! regulation of metaphase/anaphase transition of meiotic cell cycle
+
+[Term]
+id: GO:1905326 ! positive regulation of meiosis I spindle assembly checkpoint
+is_a: GO:0060903 {is_inferred="true"} ! positive regulation of meiosis I
+is_a: GO:0090232 {is_inferred="true"} ! positive regulation of spindle checkpoint
+is_a: GO:1905325 {is_inferred="true"} ! regulation of meiosis I spindle assembly checkpoint
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34506 | tberardi | 2016-07-19 17:18:51 -0700 (Tue, 19 Jul 2016) | 1 line

fixing GOD to GOC in some dbxrefs

changes in entailments

------------------------------------------------------------------------
r34503 | tberardi | 2016-07-19 16:03:02 -0700 (Tue, 19 Jul 2016) | 1 line

GH12544 NTR: Transcription factor inhibitor complex - closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34503)
+++ go_inferences.obo	(working copy)
@@ -5191,6 +5191,10 @@
 is_a: GO:0044451 {is_inferred="true"} ! nucleoplasm part
 
 [Term]
+id: GO:0005677 ! chromatin silencing complex
+is_a: GO:0090568 {is_inferred="true"} ! nuclear transcriptional repressor complex
+
+[Term]
 id: GO:0005701 ! polytene chromosome chromocenter
 is_a: GO:0010369 {is_inferred="true"} ! chromocenter
 
@@ -30756,6 +30760,10 @@
 is_a: GO:0031246 {is_inferred="true"} ! intrinsic component of periplasmic side of cell outer membrane
 
 [Term]
+id: GO:0036411 ! H-NS-Cnu complex
+is_a: GO:0090569 {is_inferred="true"} ! cytoplasmic transcriptional repressor complex
+
+[Term]
 id: GO:0036418 ! intrinsic component of mycolate outer membrane
 is_a: GO:0031230 {is_inferred="true"} ! intrinsic component of cell outer membrane
 
@@ -89491,7 +89499,7 @@
 
 [Term]
 id: GO:1990711 ! Beta-catenin-ICAT complex
-is_a: GO:0044451 {is_inferred="true"} ! nucleoplasm part
+is_a: GO:0090568 {is_inferred="true"} ! nuclear transcriptional repressor complex
 
 [Term]
 id: GO:1990712 ! HFE-transferrin receptor complex
------------------------------------------------------------------------
r34494 | termgenie | 2016-07-18 16:17:47 -0700 (Mon, 18 Jul 2016) | 3 lines

TermGenie commit for user: mah reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34494)
+++ go_inferences.obo	(working copy)
@@ -86492,7 +86492,7 @@
 
 [Term]
 id: GO:1904868 ! telomerase catalytic core complex assembly
-is_a: GO:0022618 {is_inferred="true"} ! ribonucleoprotein complex assembly
+is_a: GO:1905323 {is_inferred="true"} ! telomerase holoenzyme complex assembly
 
 [Term]
 id: GO:1904869 ! regulation of protein localization to Cajal body
@@ -88734,6 +88734,14 @@
 is_a: GO:1905320 {is_inferred="true"} ! regulation of mesenchymal stem cell migration
 
 [Term]
+id: GO:1905323 ! telomerase holoenzyme complex assembly
+is_a: GO:0022618 {is_inferred="true"} ! ribonucleoprotein complex assembly
+
+[Term]
+id: GO:1905324 ! telomere-telomerase complex assembly
+is_a: GO:0065004 {is_inferred="true"} ! protein-DNA complex assembly
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34455 | termgenie | 2016-07-15 16:54:30 -0700 (Fri, 15 Jul 2016) | 4 lines

TermGenie commit for user: sl reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34455)
+++ go_inferences.obo	(working copy)
@@ -88720,6 +88720,20 @@
 is_a: GO:0016477 {is_inferred="true"} ! cell migration
 
 [Term]
+id: GO:1905320 ! regulation of mesenchymal stem cell migration
+is_a: GO:0030334 {is_inferred="true"} ! regulation of cell migration
+
+[Term]
+id: GO:1905321 ! negative regulation of mesenchymal stem cell migration
+is_a: GO:0030336 {is_inferred="true"} ! negative regulation of cell migration
+is_a: GO:1905320 {is_inferred="true"} ! regulation of mesenchymal stem cell migration
+
+[Term]
+id: GO:1905322 ! positive regulation of mesenchymal stem cell migration
+is_a: GO:0030335 {is_inferred="true"} ! positive regulation of cell migration
+is_a: GO:1905320 {is_inferred="true"} ! regulation of mesenchymal stem cell migration
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34452 | termgenie | 2016-07-15 05:08:44 -0700 (Fri, 15 Jul 2016) | 4 lines

See https://github.com/geneontology/go-ontology/issues/12533

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34453)
+++ go_inferences.obo	(working copy)
@@ -88716,6 +88716,10 @@
 is_a: GO:0033316 {is_inferred="true"} ! meiotic spindle assembly checkpoint
 
 [Term]
+id: GO:1905319 ! mesenchymal stem cell migration
+is_a: GO:0016477 {is_inferred="true"} ! cell migration
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34442 | termgenie | 2016-07-14 02:35:16 -0700 (Thu, 14 Jul 2016) | 2 lines

TermGenie commit for user: vw reviewed by mec

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34442)
+++ go_inferences.obo	(working copy)
@@ -88712,6 +88712,10 @@
 is_a: GO:0003203 {is_inferred="true"} ! endocardial cushion morphogenesis
 
 [Term]
+id: GO:1905318 ! meiosis I spindle assembly checkpoint
+is_a: GO:0033316 {is_inferred="true"} ! meiotic spindle assembly checkpoint
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34440 | mcourtot | 2016-07-14 00:54:02 -0700 (Thu, 14 Jul 2016) | 1 line

adding synonym GO:1990814. Closes #12538

changes in entailments

------------------------------------------------------------------------
r34436 | dph | 2016-07-13 10:18:37 -0700 (Wed, 13 Jul 2016) | 2 lines

GH12529-closed

changes in entailments

------------------------------------------------------------------------
r34434 | dph | 2016-07-13 09:59:20 -0700 (Wed, 13 Jul 2016) | 2 lines

GH12530 and GH12528

changes in entailments

------------------------------------------------------------------------
r34432 | dph | 2016-07-13 09:35:36 -0700 (Wed, 13 Jul 2016) | 2 lines

Tweaked the definition of cohesin loading.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34432)
+++ go_inferences.obo	(working copy)
@@ -88705,11 +88705,11 @@
 
 [Term]
 id: GO:1905316 ! superior endocardial cushion morphogenesis
-is_a: GO:0009653 {is_inferred="true"} ! anatomical structure morphogenesis
+is_a: GO:0003203 {is_inferred="true"} ! endocardial cushion morphogenesis
 
 [Term]
 id: GO:1905317 ! inferior endocardial cushion morphogenesis
-is_a: GO:0009653 {is_inferred="true"} ! anatomical structure morphogenesis
+is_a: GO:0003203 {is_inferred="true"} ! endocardial cushion morphogenesis
 
 [Term]
 id: GO:1990000 ! amyloid fibril formation
------------------------------------------------------------------------
r34424 | termgenie | 2016-07-13 01:02:07 -0700 (Wed, 13 Jul 2016) | 2 lines

TermGenie commit for user: rl reviewed by mec

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34424)
+++ go_inferences.obo	(working copy)
@@ -88700,6 +88700,18 @@
 is_a: GO:0003170 {is_inferred="true"} ! heart valve development
 
 [Term]
+id: GO:1905315 ! cell proliferation involved in endocardial cushion morphogenesis
+is_a: GO:0061323 {is_inferred="true"} ! cell proliferation involved in heart morphogenesis
+
+[Term]
+id: GO:1905316 ! superior endocardial cushion morphogenesis
+is_a: GO:0009653 {is_inferred="true"} ! anatomical structure morphogenesis
+
+[Term]
+id: GO:1905317 ! inferior endocardial cushion morphogenesis
+is_a: GO:0009653 {is_inferred="true"} ! anatomical structure morphogenesis
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34419 | termgenie | 2016-07-12 05:51:10 -0700 (Tue, 12 Jul 2016) | 2 lines

TermGenie commit for user: rl reviewed by mec

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34419)
+++ go_inferences.obo	(working copy)
@@ -4435,7 +4435,7 @@
 [Term]
 id: GO:0003302 ! transforming growth factor beta receptor signaling pathway involved in heart jogging
 is_a: GO:0035463 {is_inferred="true"} ! transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry
-is_a: GO:0061311 {is_inferred="true"} ! cell surface receptor signaling pathway involved in heart development
+is_a: GO:1905313 {is_inferred="true"} ! transforming growth factor beta receptor signaling pathway involved in heart development
 
 [Term]
 id: GO:0003303 ! BMP signaling pathway involved in heart jogging
@@ -88691,6 +88691,11 @@
 is_a: GO:1905310 {is_inferred="true"} ! regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis
 
 [Term]
+id: GO:1905313 ! transforming growth factor beta receptor signaling pathway involved in heart development
+is_a: GO:0007179 {is_inferred="true"} ! transforming growth factor beta receptor signaling pathway
+is_a: GO:0061311 {is_inferred="true"} ! cell surface receptor signaling pathway involved in heart development
+
+[Term]
 id: GO:1905314 ! semi-lunar valve development
 is_a: GO:0003170 {is_inferred="true"} ! heart valve development
 
------------------------------------------------------------------------
r34417 | termgenie | 2016-07-12 04:14:22 -0700 (Tue, 12 Jul 2016) | 2 lines

TermGenie commit for user: rl reviewed by mec

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34417)
+++ go_inferences.obo	(working copy)
@@ -4294,6 +4294,14 @@
 is_a: GO:0003171 {is_inferred="true"} ! atrioventricular valve development
 
 [Term]
+id: GO:0003176 ! aortic valve development
+is_a: GO:1905314 {is_inferred="true"} ! semi-lunar valve development
+
+[Term]
+id: GO:0003177 ! pulmonary valve development
+is_a: GO:1905314 {is_inferred="true"} ! semi-lunar valve development
+
+[Term]
 id: GO:0003183 ! mitral valve morphogenesis
 is_a: GO:0003181 {is_inferred="true"} ! atrioventricular valve morphogenesis
 
@@ -88683,6 +88691,10 @@
 is_a: GO:1905310 {is_inferred="true"} ! regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis
 
 [Term]
+id: GO:1905314 ! semi-lunar valve development
+is_a: GO:0003170 {is_inferred="true"} ! heart valve development
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34412 | termgenie | 2016-07-12 03:11:07 -0700 (Tue, 12 Jul 2016) | 4 lines

TermGenie commit for user: rl reviewed by mec

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34412)
+++ go_inferences.obo	(working copy)
@@ -88659,6 +88659,30 @@
 is_a: GO:1903829 {is_inferred="true"} ! positive regulation of cellular protein localization
 
 [Term]
+id: GO:1905310 ! regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis
+is_a: GO:0030334 {is_inferred="true"} ! regulation of cell migration
+is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
+is_a: GO:1905207 {is_inferred="true"} ! regulation of cardiocyte differentiation
+is_a: GO:1905292 {is_inferred="true"} ! regulation of neural crest cell differentiation
+is_a: GO:2000826 {is_inferred="true"} ! regulation of heart morphogenesis
+
+[Term]
+id: GO:1905311 ! negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis
+is_a: GO:0010721 {is_inferred="true"} ! negative regulation of cell development
+is_a: GO:0030336 {is_inferred="true"} ! negative regulation of cell migration
+is_a: GO:1905208 {is_inferred="true"} ! negative regulation of cardiocyte differentiation
+is_a: GO:1905293 {is_inferred="true"} ! negative regulation of neural crest cell differentiation
+is_a: GO:1905310 {is_inferred="true"} ! regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis
+
+[Term]
+id: GO:1905312 ! positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis
+is_a: GO:0010720 {is_inferred="true"} ! positive regulation of cell development
+is_a: GO:0030335 {is_inferred="true"} ! positive regulation of cell migration
+is_a: GO:1905209 {is_inferred="true"} ! positive regulation of cardiocyte differentiation
+is_a: GO:1905294 {is_inferred="true"} ! positive regulation of neural crest cell differentiation
+is_a: GO:1905310 {is_inferred="true"} ! regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34404 | dph | 2016-07-11 11:53:16 -0700 (Mon, 11 Jul 2016) | 2 lines

Changed intersection_of genus of transport along microtubule to transport.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34404)
+++ go_inferences.obo	(working copy)
@@ -8711,11 +8711,6 @@
 is_a: GO:0004871 {is_inferred="true"} ! signal transducer activity
 
 [Term]
-id: GO:0008088 ! axo-dendritic transport
-is_a: GO:0030705 {is_inferred="true"} ! cytoskeleton-dependent intracellular transport
-is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
-
-[Term]
 id: GO:0008089 ! anterograde axonal transport
 is_a: GO:0098930 {is_inferred="true"} ! axonal transport
 
@@ -13762,9 +13757,9 @@
 is_a: GO:0060238 {is_inferred="true"} ! regulation of signal transduction involved in conjugation with cellular fusion
 
 [Term]
-id: GO:0010970 ! establishment of localization by movement along microtubule
-is_a: GO:0051234 {is_inferred="true"} ! establishment of localization
-is_a: GO:1902578 {is_inferred="true"} ! single-organism localization
+id: GO:0010970 ! transport along microtubule
+is_a: GO:0030705 {is_inferred="true"} ! cytoskeleton-dependent intracellular transport
+is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:0010971 ! positive regulation of G2/M transition of mitotic cell cycle
@@ -22831,9 +22826,7 @@
 
 [Term]
 id: GO:0031887 ! lipid particle transport along microtubule
-is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
-is_a: GO:0051656 {is_inferred="true"} ! establishment of organelle localization
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
+is_a: GO:0072384 {is_inferred="true"} ! organelle transport along microtubule
 
 [Term]
 id: GO:0031897 ! Tic complex
@@ -31259,10 +31252,8 @@
 
 [Term]
 id: GO:0042073 ! intraciliary transport
-is_a: GO:0015031 {is_inferred="true"} ! protein transport
 is_a: GO:0031503 {is_inferred="true"} ! protein complex localization
-is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
-is_a: GO:0051649 {is_inferred="true"} ! establishment of localization in cell
+is_a: GO:0098840 {is_inferred="true"} ! protein transport along microtubule
 
 [Term]
 id: GO:0042078 ! germ-line stem cell division
@@ -55912,9 +55903,7 @@
 
 [Term]
 id: GO:0072384 ! organelle transport along microtubule
-is_a: GO:0030705 {is_inferred="true"} ! cytoskeleton-dependent intracellular transport
 is_a: GO:0051656 {is_inferred="true"} ! establishment of organelle localization
-is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
 id: GO:0072387 ! flavin adenine dinucleotide metabolic process
@@ -60882,9 +60871,7 @@
 [Term]
 id: GO:0098840 ! protein transport along microtubule
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
-is_a: GO:0010970 {is_inferred="true"} ! establishment of localization by movement along microtubule
-is_a: GO:0030705 {is_inferred="true"} ! cytoskeleton-dependent intracellular transport
-is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
+is_a: GO:0010970 {is_inferred="true"} ! transport along microtubule
 
 [Term]
 id: GO:0098841 ! protein localization to cell division site after cytokinesis
@@ -61851,10 +61838,7 @@
 
 [Term]
 id: GO:0099606 ! microtubule plus-end directed mitotic chromosome migration
-is_a: GO:0010970 {is_inferred="true"} ! establishment of localization by movement along microtubule
 is_a: GO:0051303 {is_inferred="true"} ! establishment of chromosome localization
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
-is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
 id: GO:0099613 ! protein targeting to cell wall
------------------------------------------------------------------------
r34348 | dph | 2016-07-09 07:33:35 -0700 (Sat, 09 Jul 2016) | 2 lines

GH12525-closed

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34348)
+++ go_inferences.obo	(working copy)
@@ -51081,6 +51081,10 @@
 is_a: GO:0015081 {is_inferred="true"} ! sodium ion transmembrane transporter activity
 
 [Term]
+id: GO:0061773 ! eNoSc complex
+is_a: GO:0044452 {is_inferred="true"} ! nucleolar part
+
+[Term]
 id: GO:0065002 ! intracellular protein transmembrane transport
 is_a: GO:0006886 {is_inferred="true"} ! intracellular protein transport
 is_a: GO:0071806 {is_inferred="true"} ! protein transmembrane transport
------------------------------------------------------------------------
r34345 | dph | 2016-07-09 07:03:42 -0700 (Sat, 09 Jul 2016) | 2 lines

GH12524-closed

changes in entailments

------------------------------------------------------------------------
r34343 | dph | 2016-07-09 06:57:21 -0700 (Sat, 09 Jul 2016) | 2 lines

GH12527-closed

changes in entailments

------------------------------------------------------------------------
r34342 | dph | 2016-07-09 06:50:57 -0700 (Sat, 09 Jul 2016) | 2 lines

GH12523-closed

changes in entailments

------------------------------------------------------------------------
r34340 | dph | 2016-07-09 06:36:09 -0700 (Sat, 09 Jul 2016) | 2 lines

GH12513-closed

changes in entailments

------------------------------------------------------------------------
r34333 | termgenie | 2016-07-08 18:56:32 -0700 (Fri, 08 Jul 2016) | 2 lines

TermGenie commit for user: vw reviewed by dph

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34333)
+++ go_inferences.obo	(working copy)
@@ -88655,14 +88655,22 @@
 
 [Term]
 id: GO:1905307 ! response to miconazole
-is_a: GO:0050896 {is_inferred="true"} ! response to stimulus
+is_a: GO:0010243 {is_inferred="true"} ! response to organonitrogen compound
+is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
 
 [Term]
 id: GO:1905308 ! cellular response to miconazole
-is_a: GO:0070887 {is_inferred="true"} ! cellular response to chemical stimulus
+is_a: GO:0071407 {is_inferred="true"} ! cellular response to organic cyclic compound
+is_a: GO:0071417 {is_inferred="true"} ! cellular response to organonitrogen compound
 is_a: GO:1905307 {is_inferred="true"} ! response to miconazole
 
 [Term]
+id: GO:1905309 ! positive regulation of cohesin loading
+is_a: GO:0045876 {is_inferred="true"} ! positive regulation of sister chromatid cohesion
+is_a: GO:0071922 {is_inferred="true"} ! regulation of cohesin loading
+is_a: GO:1903829 {is_inferred="true"} ! positive regulation of cellular protein localization
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34235 | dph | 2016-07-06 12:14:29 -0700 (Wed, 06 Jul 2016) | 2 lines

Fixed a typo in the synonym for GO:0010970.

changes in entailments

------------------------------------------------------------------------
r34233 | termgenie | 2016-07-06 12:01:20 -0700 (Wed, 06 Jul 2016) | 3 lines

TermGenie commit for user: al reviewed by dph

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34233)
+++ go_inferences.obo	(working copy)
@@ -88630,6 +88630,39 @@
 is_a: GO:1905301 {is_inferred="true"} ! regulation of macropinocytosis
 
 [Term]
+id: GO:1905304 ! regulation of cardiac myofibril assembly
+is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
+is_a: GO:0032956 {is_inferred="true"} ! regulation of actin cytoskeleton organization
+is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
+is_a: GO:1902115 {is_inferred="true"} ! regulation of organelle assembly
+is_a: GO:2000725 {is_inferred="true"} ! regulation of cardiac muscle cell differentiation
+
+[Term]
+id: GO:1905305 ! negative regulation of cardiac myofibril assembly
+is_a: GO:0010721 {is_inferred="true"} ! negative regulation of cell development
+is_a: GO:0051494 {is_inferred="true"} ! negative regulation of cytoskeleton organization
+is_a: GO:1902116 {is_inferred="true"} ! negative regulation of organelle assembly
+is_a: GO:1905304 {is_inferred="true"} ! regulation of cardiac myofibril assembly
+is_a: GO:2000726 {is_inferred="true"} ! negative regulation of cardiac muscle cell differentiation
+
+[Term]
+id: GO:1905306 ! positive regulation of cardiac myofibril assembly
+is_a: GO:0010720 {is_inferred="true"} ! positive regulation of cell development
+is_a: GO:0051495 {is_inferred="true"} ! positive regulation of cytoskeleton organization
+is_a: GO:1902117 {is_inferred="true"} ! positive regulation of organelle assembly
+is_a: GO:1905304 {is_inferred="true"} ! regulation of cardiac myofibril assembly
+is_a: GO:2000727 {is_inferred="true"} ! positive regulation of cardiac muscle cell differentiation
+
+[Term]
+id: GO:1905307 ! response to miconazole
+is_a: GO:0050896 {is_inferred="true"} ! response to stimulus
+
+[Term]
+id: GO:1905308 ! cellular response to miconazole
+is_a: GO:0070887 {is_inferred="true"} ! cellular response to chemical stimulus
+is_a: GO:1905307 {is_inferred="true"} ! response to miconazole
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34225 | termgenie | 2016-07-05 07:09:51 -0700 (Tue, 05 Jul 2016) | 4 lines

TermGenie commit for user: pad reviewed by dph

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34225)
+++ go_inferences.obo	(working copy)
@@ -88616,6 +88616,20 @@
 is_a: GO:1905298 {is_inferred="true"} ! regulation of intestinal epithelial cell development
 
 [Term]
+id: GO:1905301 ! regulation of macropinocytosis
+is_a: GO:0048548 {is_inferred="true"} ! regulation of pinocytosis
+
+[Term]
+id: GO:1905302 ! negative regulation of macropinocytosis
+is_a: GO:0048550 {is_inferred="true"} ! negative regulation of pinocytosis
+is_a: GO:1905301 {is_inferred="true"} ! regulation of macropinocytosis
+
+[Term]
+id: GO:1905303 ! positive regulation of macropinocytosis
+is_a: GO:0048549 {is_inferred="true"} ! positive regulation of pinocytosis
+is_a: GO:1905301 {is_inferred="true"} ! regulation of macropinocytosis
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34223 | dph | 2016-07-05 06:19:35 -0700 (Tue, 05 Jul 2016) | 2 lines

Added synonym for exon-exon junction complex. GH12515-closed.

changes in entailments

------------------------------------------------------------------------
r34215 | paola | 2016-07-04 02:19:05 -0700 (Mon, 04 Jul 2016) | 4 lines

GH chromosome organization is_a children #8689 - work in progress -

changes in entailments

------------------------------------------------------------------------
r34185 | termgenie | 2016-06-30 09:55:19 -0700 (Thu, 30 Jun 2016) | 4 lines

TermGenie commit for user: rph reviewed by dos

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34185)
+++ go_inferences.obo	(working copy)
@@ -88597,6 +88597,25 @@
 is_a: GO:1905295 {is_inferred="true"} ! regulation of neural crest cell fate specification
 
 [Term]
+id: GO:1905298 ! regulation of intestinal epithelial cell development
+is_a: GO:0030856 {is_inferred="true"} ! regulation of epithelial cell differentiation
+is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
+
+[Term]
+id: GO:1905299 ! negative regulation of intestinal epithelial cell development
+is_a: GO:0010721 {is_inferred="true"} ! negative regulation of cell development
+is_a: GO:0030857 {is_inferred="true"} ! negative regulation of epithelial cell differentiation
+is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
+is_a: GO:1905298 {is_inferred="true"} ! regulation of intestinal epithelial cell development
+
+[Term]
+id: GO:1905300 ! positive regulation of intestinal epithelial cell development
+is_a: GO:0010720 {is_inferred="true"} ! positive regulation of cell development
+is_a: GO:0030858 {is_inferred="true"} ! positive regulation of epithelial cell differentiation
+is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
+is_a: GO:1905298 {is_inferred="true"} ! regulation of intestinal epithelial cell development
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34177 | termgenie | 2016-06-29 17:38:08 -0700 (Wed, 29 Jun 2016) | 4 lines

TermGenie commit for user: rl reviewed by dos

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34177)
+++ go_inferences.obo	(working copy)
@@ -55807,17 +55807,14 @@
 
 [Term]
 id: GO:0072335 ! regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation
-is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
 is_a: GO:0060828 {is_inferred="true"} ! regulation of canonical Wnt signaling pathway
-is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
+is_a: GO:1905292 {is_inferred="true"} ! regulation of neural crest cell differentiation
 
 [Term]
 id: GO:0072336 ! negative regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation
-is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
-is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
-is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
 is_a: GO:0072335 {is_inferred="true"} ! regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation
 is_a: GO:0090090 {is_inferred="true"} ! negative regulation of canonical Wnt signaling pathway
+is_a: GO:1905293 {is_inferred="true"} ! negative regulation of neural crest cell differentiation
 
 [Term]
 id: GO:0072337 ! modified amino acid transport
@@ -55905,11 +55902,9 @@
 
 [Term]
 id: GO:0072381 ! positive regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation
-is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
-is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
-is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
 is_a: GO:0072335 {is_inferred="true"} ! regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation
 is_a: GO:0090263 {is_inferred="true"} ! positive regulation of canonical Wnt signaling pathway
+is_a: GO:1905294 {is_inferred="true"} ! positive regulation of neural crest cell differentiation
 
 [Term]
 id: GO:0072384 ! organelle transport along microtubule
@@ -88563,6 +88558,45 @@
 is_a: GO:1905289 {is_inferred="true"} ! regulation of CAMKK-AMPK signaling cascade
 
 [Term]
+id: GO:1905292 ! regulation of neural crest cell differentiation
+is_a: GO:0045595 {is_inferred="true"} ! regulation of cell differentiation
+is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
+
+[Term]
+id: GO:1905293 ! negative regulation of neural crest cell differentiation
+is_a: GO:0045596 {is_inferred="true"} ! negative regulation of cell differentiation
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
+is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
+is_a: GO:1905292 {is_inferred="true"} ! regulation of neural crest cell differentiation
+
+[Term]
+id: GO:1905294 ! positive regulation of neural crest cell differentiation
+is_a: GO:0045597 {is_inferred="true"} ! positive regulation of cell differentiation
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
+is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
+is_a: GO:1905292 {is_inferred="true"} ! regulation of neural crest cell differentiation
+
+[Term]
+id: GO:1905295 ! regulation of neural crest cell fate specification
+is_a: GO:0042659 {is_inferred="true"} ! regulation of cell fate specification
+is_a: GO:0090299 {is_inferred="true"} ! regulation of neural crest formation
+is_a: GO:1905292 {is_inferred="true"} ! regulation of neural crest cell differentiation
+
+[Term]
+id: GO:1905296 ! negative regulation of neural crest cell fate specification
+is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
+is_a: GO:0090301 {is_inferred="true"} ! negative regulation of neural crest formation
+is_a: GO:1905293 {is_inferred="true"} ! negative regulation of neural crest cell differentiation
+is_a: GO:1905295 {is_inferred="true"} ! regulation of neural crest cell fate specification
+
+[Term]
+id: GO:1905297 ! positive regulation of neural crest cell fate specification
+is_a: GO:0042660 {is_inferred="true"} ! positive regulation of cell fate specification
+is_a: GO:0090300 {is_inferred="true"} ! positive regulation of neural crest formation
+is_a: GO:1905294 {is_inferred="true"} ! positive regulation of neural crest cell differentiation
+is_a: GO:1905295 {is_inferred="true"} ! regulation of neural crest cell fate specification
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34122 | davidos | 2016-06-24 05:35:14 -0700 (Fri, 24 Jun 2016) | 1 line

Fixing bad PMIDS and non ascii chars

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34122)
+++ go_inferences.obo	(working copy)
@@ -471,26 +471,6 @@
 is_a: GO:0098763 {is_inferred="true"} ! mitotic cell cycle phase
 
 [Term]
-id: GO:0000237 ! leptotene
-is_a: GO:0098764 {is_inferred="true"} ! meiosis I cell cycle phase
-
-[Term]
-id: GO:0000238 ! zygotene
-is_a: GO:0098764 {is_inferred="true"} ! meiosis I cell cycle phase
-
-[Term]
-id: GO:0000239 ! pachytene
-is_a: GO:0098764 {is_inferred="true"} ! meiosis I cell cycle phase
-
-[Term]
-id: GO:0000240 ! diplotene
-is_a: GO:0098764 {is_inferred="true"} ! meiosis I cell cycle phase
-
-[Term]
-id: GO:0000241 ! diakinesis
-is_a: GO:0098764 {is_inferred="true"} ! meiosis I cell cycle phase
-
-[Term]
 id: GO:0000245 ! spliceosomal complex assembly
 is_a: GO:0022618 {is_inferred="true"} ! ribonucleoprotein complex assembly
 
@@ -823,7 +803,6 @@
 
 [Term]
 id: GO:0000758 ! agglutination involved in conjugation with mutual genetic exchange
-is_a: GO:0000771 {is_inferred="true"} ! agglutination involved in conjugation
 is_a: GO:0098630 {is_inferred="true"} ! aggregation of unicellular organisms
 
 [Term]
@@ -984,10 +963,6 @@
 is_a: GO:1903047 {is_inferred="true"} ! mitotic cell cycle process
 
 [Term]
-id: GO:0000914 ! phragmoplast assembly
-is_a: GO:1902407 {is_inferred="true"} ! assembly of actomyosin apparatus involved in mitotic cytokinesis
-
-[Term]
 id: GO:0000917 ! barrier septum assembly
 is_a: GO:0090529 {is_inferred="true"} ! cell septum assembly
 
@@ -5167,6 +5142,7 @@
 [Term]
 id: GO:0005639 ! integral component of nuclear inner membrane
 is_a: GO:0031229 {is_inferred="true"} ! intrinsic component of nuclear inner membrane
+is_a: GO:0031301 {is_inferred="true"} ! integral component of organelle membrane
 
 [Term]
 id: GO:0005640 ! nuclear outer membrane
@@ -5320,6 +5296,7 @@
 [Term]
 id: GO:0005779 ! integral component of peroxisomal membrane
 is_a: GO:0031231 {is_inferred="true"} ! intrinsic component of peroxisomal membrane
+is_a: GO:0031301 {is_inferred="true"} ! integral component of organelle membrane
 
 [Term]
 id: GO:0005785 ! signal recognition particle receptor complex
@@ -5332,7 +5309,9 @@
 
 [Term]
 id: GO:0005789 ! endoplasmic reticulum membrane
+is_a: GO:0016020 {is_inferred="true"} ! membrane
 is_a: GO:0044425 {is_inferred="true"} ! membrane part
+is_a: GO:0044432 {is_inferred="true"} ! endoplasmic reticulum part
 
 [Term]
 id: GO:0005795 ! Golgi stack
@@ -6612,10 +6591,6 @@
 is_a: GO:2001020 {is_inferred="true"} ! regulation of response to DNA damage stimulus
 
 [Term]
-id: GO:0006286 ! base-excision repair, base-free sugar-phosphate removal
-is_a: GO:0098502 {is_inferred="true"} ! DNA dephosphorylation
-
-[Term]
 id: GO:0006288 ! base-excision repair, DNA ligation
 is_a: GO:0051103 {is_inferred="true"} ! DNA ligation involved in DNA repair
 
@@ -7181,7 +7156,6 @@
 is_a: GO:0017038 {is_inferred="true"} ! protein import
 is_a: GO:0034504 {is_inferred="true"} ! protein localization to nucleus
 is_a: GO:0072594 {is_inferred="true"} ! establishment of protein localization to organelle
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 is_a: GO:1902593 {is_inferred="true"} ! single-organism nuclear import
 
 [Term]
@@ -7955,7 +7929,6 @@
 [Term]
 id: GO:0006853 ! carnitine shuttle
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
-is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
 id: GO:0006857 ! oligopeptide transport
@@ -8193,10 +8166,6 @@
 is_a: GO:0080171 {is_inferred="true"} ! lytic vacuole organization
 
 [Term]
-id: GO:0007042 ! lysosomal lumen acidification
-is_a: GO:0007035 {is_inferred="true"} ! vacuolar acidification
-
-[Term]
 id: GO:0007043 ! cell-cell junction assembly
 is_a: GO:0034329 {is_inferred="true"} ! cell junction assembly
 
@@ -8341,10 +8310,6 @@
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
-id: GO:0007128 ! meiotic prophase I
-is_a: GO:0098764 {is_inferred="true"} ! meiosis I cell cycle phase
-
-[Term]
 id: GO:0007130 ! synaptonemal complex assembly
 is_a: GO:0022607 {is_inferred="true"} ! cellular component assembly
 
@@ -8353,18 +8318,10 @@
 is_a: GO:1903046 {is_inferred="true"} ! meiotic cell cycle process
 
 [Term]
-id: GO:0007132 ! meiotic metaphase I
-is_a: GO:0098764 {is_inferred="true"} ! meiosis I cell cycle phase
-
-[Term]
 id: GO:0007133 ! meiotic anaphase I
 is_a: GO:0098764 {is_inferred="true"} ! meiosis I cell cycle phase
 
 [Term]
-id: GO:0007134 ! meiotic telophase I
-is_a: GO:0098764 {is_inferred="true"} ! meiosis I cell cycle phase
-
-[Term]
 id: GO:0007136 ! meiotic prophase II
 is_a: GO:0098765 {is_inferred="true"} ! meiosis II cell cycle phase
 
@@ -8383,7 +8340,6 @@
 [Term]
 id: GO:0007162 ! negative regulation of cell adhesion
 is_a: GO:0030155 {is_inferred="true"} ! regulation of cell adhesion
-is_a: GO:0048523 {is_inferred="true"} ! negative regulation of cellular process
 
 [Term]
 id: GO:0007175 ! negative regulation of epidermal growth factor-activated receptor activity
@@ -8939,7 +8895,6 @@
 [Term]
 id: GO:0008320 ! protein transmembrane transporter activity
 is_a: GO:0008565 {is_inferred="true"} ! protein transporter activity
-is_a: GO:0022884 {is_inferred="true"} ! macromolecule transmembrane transporter activity
 
 [Term]
 id: GO:0008324 ! cation transmembrane transporter activity
@@ -9177,10 +9132,6 @@
 is_a: GO:1901681 {is_inferred="true"} ! sulfur compound binding
 
 [Term]
-id: GO:0008979 ! prophage integrase activity
-is_a: GO:0008907 {is_inferred="true"} ! integrase activity
-
-[Term]
 id: GO:0009050 ! glycopeptide catabolic process
 is_a: GO:0043171 {is_inferred="true"} ! peptide catabolic process
 is_a: GO:1901136 {is_inferred="true"} ! carbohydrate derivative catabolic process
@@ -10544,6 +10495,10 @@
 is_a: GO:0098543 {is_inferred="true"} ! detection of other organism
 
 [Term]
+id: GO:0009615 ! response to virus
+is_a: GO:0016032 {is_inferred="true"} ! viral process
+
+[Term]
 id: GO:0009654 ! photosystem II oxygen evolving complex
 is_a: GO:0044436 {is_inferred="true"} ! thylakoid part
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
@@ -14484,8 +14439,8 @@
 
 [Term]
 id: GO:0015031 ! protein transport
-is_a: GO:0006810 {is_inferred="true"} ! transport
 is_a: GO:0008104 {is_inferred="true"} ! protein localization
+is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 
 [Term]
 id: GO:0015050 ! methane monooxygenase complex
@@ -15102,10 +15057,6 @@
 is_a: GO:0008514 {is_inferred="true"} ! organic anion transmembrane transporter activity
 
 [Term]
-id: GO:0015557 ! arginine targeting transmembrane transporter activity
-is_a: GO:0008320 {is_inferred="true"} ! protein transmembrane transporter activity
-
-[Term]
 id: GO:0015567 ! alkane transporter activity
 is_a: GO:0005215 {is_inferred="true"} ! transporter activity
 
@@ -16960,7 +16911,6 @@
 
 [Term]
 id: GO:0016558 ! protein import into peroxisome matrix
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 is_a: GO:1902589 {is_inferred="true"} ! single-organism organelle organization
 
 [Term]
@@ -18808,10 +18758,6 @@
 is_a: GO:1901566 {is_inferred="true"} ! organonitrogen compound biosynthetic process
 
 [Term]
-id: GO:0019538 ! protein metabolic process
-is_a: GO:0043170 {is_inferred="true"} ! macromolecule metabolic process
-
-[Term]
 id: GO:0019540 ! siderophore biosynthetic process from catechol
 is_a: GO:0009712 {is_inferred="true"} ! catechol-containing compound metabolic process
 
@@ -19578,6 +19524,7 @@
 
 [Term]
 id: GO:0020028 ! hemoglobin import
+is_a: GO:0045184 {is_inferred="true"} ! establishment of protein localization
 is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 
 [Term]
@@ -19646,10 +19593,6 @@
 is_a: GO:0021920 {is_inferred="true"} ! regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification
 
 [Term]
-id: GO:0021784 ! postganglionic parasympathetic fiber development
-is_a: GO:0048483 {is_inferred="true"} ! autonomic nervous system development
-
-[Term]
 id: GO:0021801 ! cerebral cortex radial glia guided migration
 is_a: GO:0022030 {is_inferred="true"} ! telencephalon glial cell migration
 
@@ -19674,10 +19617,6 @@
 is_a: GO:0022030 {is_inferred="true"} ! telencephalon glial cell migration
 
 [Term]
-id: GO:0021832 ! cell-cell adhesion involved in cerebral cortex tangential migration using cell-cell interactions
-is_a: GO:0016337 {is_inferred="true"} ! single organismal cell-cell adhesion
-
-[Term]
 id: GO:0021834 ! chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration
 is_a: GO:0050919 {is_inferred="true"} ! negative chemotaxis
 
@@ -20092,7 +20031,6 @@
 id: GO:0030050 ! vesicle transport along actin filament
 is_a: GO:0099515 {is_inferred="true"} ! actin filament-based transport
 is_a: GO:0099518 {is_inferred="true"} ! vesicle cytoskeletal trafficking
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
@@ -20200,7 +20138,6 @@
 id: GO:0030150 ! protein import into mitochondrial matrix
 is_a: GO:0070585 {is_inferred="true"} ! protein localization to mitochondrion
 is_a: GO:0072655 {is_inferred="true"} ! establishment of protein localization to mitochondrion
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
@@ -20222,7 +20159,6 @@
 
 [Term]
 id: GO:0030163 ! protein catabolic process
-is_a: GO:0009057 {is_inferred="true"} ! macromolecule catabolic process
 is_a: GO:0019538 {is_inferred="true"} ! protein metabolic process
 
 [Term]
@@ -20242,6 +20178,7 @@
 [Term]
 id: GO:0030173 ! integral component of Golgi membrane
 is_a: GO:0031228 {is_inferred="true"} ! intrinsic component of Golgi membrane
+is_a: GO:0031301 {is_inferred="true"} ! integral component of organelle membrane
 
 [Term]
 id: GO:0030174 ! regulation of DNA-dependent DNA replication initiation
@@ -20249,6 +20186,7 @@
 
 [Term]
 id: GO:0030176 ! integral component of endoplasmic reticulum membrane
+is_a: GO:0016021 {is_inferred="true"} ! integral component of membrane
 is_a: GO:0031227 {is_inferred="true"} ! intrinsic component of endoplasmic reticulum membrane
 
 [Term]
@@ -20434,6 +20372,7 @@
 
 [Term]
 id: GO:0030285 ! integral component of synaptic vesicle membrane
+is_a: GO:0031301 {is_inferred="true"} ! integral component of organelle membrane
 is_a: GO:0098563 {is_inferred="true"} ! intrinsic component of synaptic vesicle membrane
 
 [Term]
@@ -20854,6 +20793,9 @@
 
 [Term]
 id: GO:0030660 ! Golgi-associated vesicle membrane
+is_a: GO:0044431 {is_inferred="true"} ! Golgi apparatus part
+is_a: GO:0044433 {is_inferred="true"} ! cytoplasmic vesicle part
+is_a: GO:0098588 {is_inferred="true"} ! bounding membrane of organelle
 is_a: GO:0098805 {is_inferred="true"} ! whole membrane
 
 [Term]
@@ -20867,6 +20809,11 @@
 is_a: GO:0098805 {is_inferred="true"} ! whole membrane
 
 [Term]
+id: GO:0030663 ! COPI-coated vesicle membrane
+is_a: GO:0030660 {is_inferred="true"} ! Golgi-associated vesicle membrane
+is_a: GO:0030662 {is_inferred="true"} ! coated vesicle membrane
+
+[Term]
 id: GO:0030666 ! endocytic vesicle membrane
 is_a: GO:0098588 {is_inferred="true"} ! bounding membrane of organelle
 is_a: GO:0098805 {is_inferred="true"} ! whole membrane
@@ -21312,6 +21259,14 @@
 is_a: GO:0030865 {is_inferred="true"} ! cortical cytoskeleton organization
 
 [Term]
+id: GO:0030867 ! rough endoplasmic reticulum membrane
+is_a: GO:0098588 {is_inferred="true"} ! bounding membrane of organelle
+
+[Term]
+id: GO:0030868 ! smooth endoplasmic reticulum membrane
+is_a: GO:0098588 {is_inferred="true"} ! bounding membrane of organelle
+
+[Term]
 id: GO:0030876 ! interleukin-20 receptor complex
 is_a: GO:0098802 {is_inferred="true"} ! plasma membrane receptor complex
 
@@ -21523,7 +21478,6 @@
 [Term]
 id: GO:0031022 ! nuclear migration along microfilament
 is_a: GO:0099515 {is_inferred="true"} ! actin filament-based transport
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
@@ -21760,10 +21714,12 @@
 
 [Term]
 id: GO:0031165 ! integral component of contractile vacuolar membrane
+is_a: GO:0031166 {is_inferred="true"} ! integral component of vacuolar membrane
 is_a: GO:0031311 {is_inferred="true"} ! intrinsic component of contractile vacuolar membrane
 
 [Term]
 id: GO:0031166 ! integral component of vacuolar membrane
+is_a: GO:0031301 {is_inferred="true"} ! integral component of organelle membrane
 is_a: GO:0031310 {is_inferred="true"} ! intrinsic component of vacuolar membrane
 
 [Term]
@@ -21821,10 +21777,38 @@
 is_a: GO:0044724 {is_inferred="true"} ! single-organism carbohydrate catabolic process
 
 [Term]
+id: GO:0031227 ! intrinsic component of endoplasmic reticulum membrane
+is_a: GO:0031224 {is_inferred="true"} ! intrinsic component of membrane
+is_a: GO:0044432 {is_inferred="true"} ! endoplasmic reticulum part
+
+[Term]
+id: GO:0031228 ! intrinsic component of Golgi membrane
+is_a: GO:0031300 {is_inferred="true"} ! intrinsic component of organelle membrane
+is_a: GO:0044431 {is_inferred="true"} ! Golgi apparatus part
+
+[Term]
+id: GO:0031229 ! intrinsic component of nuclear inner membrane
+is_a: GO:0031300 {is_inferred="true"} ! intrinsic component of organelle membrane
+is_a: GO:0044453 {is_inferred="true"} ! nuclear membrane part
+
+[Term]
+id: GO:0031231 ! intrinsic component of peroxisomal membrane
+is_a: GO:0031300 {is_inferred="true"} ! intrinsic component of organelle membrane
+is_a: GO:0044439 {is_inferred="true"} ! peroxisomal part
+
+[Term]
 id: GO:0031237 ! intrinsic component of periplasmic side of plasma membrane
 is_a: GO:0031233 {is_inferred="true"} ! intrinsic component of external side of plasma membrane
 
 [Term]
+id: GO:0031243 ! intrinsic component of external side of cell outer membrane
+is_a: GO:0031230 {is_inferred="true"} ! intrinsic component of cell outer membrane
+
+[Term]
+id: GO:0031246 ! intrinsic component of periplasmic side of cell outer membrane
+is_a: GO:0031230 {is_inferred="true"} ! intrinsic component of cell outer membrane
+
+[Term]
 id: GO:0031247 ! actin rod assembly
 is_a: GO:0051017 {is_inferred="true"} ! actin filament bundle assembly
 
@@ -21937,6 +21921,7 @@
 
 [Term]
 id: GO:0031300 ! intrinsic component of organelle membrane
+is_a: GO:0031224 {is_inferred="true"} ! intrinsic component of membrane
 is_a: GO:0044422 {is_inferred="true"} ! organelle part
 
 [Term]
@@ -21946,6 +21931,7 @@
 [Term]
 id: GO:0031302 ! intrinsic component of endosome membrane
 is_a: GO:0031310 {is_inferred="true"} ! intrinsic component of vacuolar membrane
+is_a: GO:0044440 {is_inferred="true"} ! endosomal part
 
 [Term]
 id: GO:0031303 ! integral component of endosome membrane
@@ -21959,6 +21945,7 @@
 [Term]
 id: GO:0031305 ! integral component of mitochondrial inner membrane
 is_a: GO:0031304 {is_inferred="true"} ! intrinsic component of mitochondrial inner membrane
+is_a: GO:0032592 {is_inferred="true"} ! integral component of mitochondrial membrane
 
 [Term]
 id: GO:0031306 ! intrinsic component of mitochondrial outer membrane
@@ -21967,12 +21954,24 @@
 [Term]
 id: GO:0031307 ! integral component of mitochondrial outer membrane
 is_a: GO:0031306 {is_inferred="true"} ! intrinsic component of mitochondrial outer membrane
+is_a: GO:0032592 {is_inferred="true"} ! integral component of mitochondrial membrane
 
 [Term]
+id: GO:0031308 ! intrinsic component of nuclear outer membrane
+is_a: GO:0031300 {is_inferred="true"} ! intrinsic component of organelle membrane
+is_a: GO:0044453 {is_inferred="true"} ! nuclear membrane part
+
+[Term]
 id: GO:0031309 ! integral component of nuclear outer membrane
+is_a: GO:0031301 {is_inferred="true"} ! integral component of organelle membrane
 is_a: GO:0031308 {is_inferred="true"} ! intrinsic component of nuclear outer membrane
 
 [Term]
+id: GO:0031310 ! intrinsic component of vacuolar membrane
+is_a: GO:0031300 {is_inferred="true"} ! intrinsic component of organelle membrane
+is_a: GO:0044437 {is_inferred="true"} ! vacuolar part
+
+[Term]
 id: GO:0031313 ! extrinsic component of endosome membrane
 is_a: GO:0000306 {is_inferred="true"} ! extrinsic component of vacuolar membrane
 
@@ -22125,15 +22124,23 @@
 is_a: GO:0048584 {is_inferred="true"} ! positive regulation of response to stimulus
 
 [Term]
+id: GO:0031350 ! intrinsic component of plastid membrane
+is_a: GO:0031300 {is_inferred="true"} ! intrinsic component of organelle membrane
+is_a: GO:0044435 {is_inferred="true"} ! plastid part
+
+[Term]
 id: GO:0031351 ! integral component of plastid membrane
+is_a: GO:0031301 {is_inferred="true"} ! integral component of organelle membrane
 is_a: GO:0031350 {is_inferred="true"} ! intrinsic component of plastid membrane
 
 [Term]
 id: GO:0031353 ! integral component of plastid inner membrane
+is_a: GO:0031351 {is_inferred="true"} ! integral component of plastid membrane
 is_a: GO:0031352 {is_inferred="true"} ! intrinsic component of plastid inner membrane
 
 [Term]
 id: GO:0031355 ! integral component of plastid outer membrane
+is_a: GO:0031351 {is_inferred="true"} ! integral component of plastid membrane
 is_a: GO:0031354 {is_inferred="true"} ! intrinsic component of plastid outer membrane
 
 [Term]
@@ -22143,6 +22150,7 @@
 
 [Term]
 id: GO:0031359 ! integral component of chloroplast outer membrane
+is_a: GO:0031355 {is_inferred="true"} ! integral component of plastid outer membrane
 is_a: GO:0031358 {is_inferred="true"} ! intrinsic component of chloroplast outer membrane
 
 [Term]
@@ -24514,6 +24522,10 @@
 is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
 
 [Term]
+id: GO:0032580 ! Golgi cisterna membrane
+is_a: GO:0000139 {is_inferred="true"} ! Golgi membrane
+
+[Term]
 id: GO:0032584 ! growth cone membrane
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
 
@@ -24532,12 +24544,12 @@
 
 [Term]
 id: GO:0032592 ! integral component of mitochondrial membrane
+is_a: GO:0031301 {is_inferred="true"} ! integral component of organelle membrane
 is_a: GO:0098573 {is_inferred="true"} ! intrinsic component of mitochondrial membrane
 
 [Term]
 id: GO:0032594 ! protein transport within lipid bilayer
 is_a: GO:0051668 {is_inferred="true"} ! localization within membrane
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
@@ -25914,6 +25926,10 @@
 is_a: GO:0044464 {is_inferred="true"} ! cell part
 
 [Term]
+id: GO:0033017 ! sarcoplasmic reticulum membrane
+is_a: GO:0098588 {is_inferred="true"} ! bounding membrane of organelle
+
+[Term]
 id: GO:0033020 ! cyclopentanol metabolic process
 is_a: GO:0006066 {is_inferred="true"} ! alcohol metabolic process
 is_a: GO:1901360 {is_inferred="true"} ! organic cyclic compound metabolic process
@@ -27596,6 +27612,7 @@
 
 [Term]
 id: GO:0034045 ! pre-autophagosomal structure membrane
+is_a: GO:0044444 {is_inferred="true"} ! cytoplasmic part
 is_a: GO:0098805 {is_inferred="true"} ! whole membrane
 
 [Term]
@@ -28442,6 +28459,7 @@
 
 [Term]
 id: GO:0034436 ! glycoprotein transport
+is_a: GO:0045184 {is_inferred="true"} ! establishment of protein localization
 is_a: GO:1901264 {is_inferred="true"} ! carbohydrate derivative transport
 
 [Term]
@@ -28656,7 +28674,6 @@
 [Term]
 id: GO:0034642 ! mitochondrion migration along actin filament
 is_a: GO:0099515 {is_inferred="true"} ! actin filament-based transport
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
@@ -30738,8 +30755,13 @@
 is_a: GO:0031246 {is_inferred="true"} ! intrinsic component of periplasmic side of cell outer membrane
 
 [Term]
+id: GO:0036418 ! intrinsic component of mycolate outer membrane
+is_a: GO:0031230 {is_inferred="true"} ! intrinsic component of cell outer membrane
+
+[Term]
 id: GO:0036419 ! integral component of mycolate outer membrane
 is_a: GO:0036418 {is_inferred="true"} ! intrinsic component of mycolate outer membrane
+is_a: GO:0045203 {is_inferred="true"} ! integral component of cell outer membrane
 
 [Term]
 id: GO:0036444 ! calcium ion transmembrane import into mitochondrion
@@ -31055,6 +31077,10 @@
 is_a: GO:0044423 {is_inferred="true"} ! virion part
 
 [Term]
+id: GO:0039667 ! viral entry into host cell via pilus retraction
+is_a: GO:0016032 {is_inferred="true"} ! viral process
+
+[Term]
 id: GO:0039688 ! viral double stranded DNA replication via reverse transcription
 is_a: GO:0016070 {is_inferred="true"} ! RNA metabolic process
 
@@ -32743,10 +32769,6 @@
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
 
 [Term]
-id: GO:0042740 ! exogenous antibiotic catabolic process
-is_a: GO:0017001 {is_inferred="true"} ! antibiotic catabolic process
-
-[Term]
 id: GO:0042742 ! defense response to bacterium
 is_a: GO:0009617 {is_inferred="true"} ! response to bacterium
 is_a: GO:0098542 {is_inferred="true"} ! defense response to other organism
@@ -33331,6 +33353,7 @@
 [Term]
 id: GO:0042953 ! lipoprotein transport
 is_a: GO:0044872 {is_inferred="true"} ! lipoprotein localization
+is_a: GO:0045184 {is_inferred="true"} ! establishment of protein localization
 is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 
 [Term]
@@ -33918,7 +33941,6 @@
 id: GO:0043303 ! mast cell degranulation
 is_a: GO:0032418 {is_inferred="true"} ! lysosome localization
 is_a: GO:0051656 {is_inferred="true"} ! establishment of organelle localization
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
@@ -34836,10 +34858,6 @@
 is_a: GO:0019829 {is_inferred="true"} ! cation-transporting ATPase activity
 
 [Term]
-id: GO:0043690 ! cell-cell adhesion involved in flocculation via cell wall protein-carbohydrate interaction
-is_a: GO:0043689 {is_inferred="true"} ! cell-cell adhesion involved in flocculation
-
-[Term]
 id: GO:0043692 ! monoterpene metabolic process
 is_a: GO:0042214 {is_inferred="true"} ! terpene metabolic process
 
@@ -34863,10 +34881,6 @@
 is_a: GO:0098740 {is_inferred="true"} ! multi organism cell adhesion
 
 [Term]
-id: GO:0043707 ! cell adhesion involved in single-species biofilm formation in or on host organism
-is_a: GO:0043709 {is_inferred="true"} ! cell adhesion involved in single-species biofilm formation
-
-[Term]
 id: GO:0043709 ! cell adhesion involved in single-species biofilm formation
 is_a: GO:0043708 {is_inferred="true"} ! cell adhesion involved in biofilm formation
 
@@ -35199,6 +35213,7 @@
 [Term]
 id: GO:0044214 ! spanning component of plasma membrane
 is_a: GO:0005887 {is_inferred="true"} ! integral component of plasma membrane
+is_a: GO:0089717 {is_inferred="true"} ! spanning component of membrane
 
 [Term]
 id: GO:0044225 ! apical pole of neuron
@@ -35682,6 +35697,7 @@
 
 [Term]
 id: GO:0044764 ! multi-organism cellular process
+is_a: GO:0009987 {is_inferred="true"} ! cellular process
 is_a: GO:0051704 {is_inferred="true"} ! multi-organism process
 
 [Term]
@@ -35800,11 +35816,6 @@
 is_a: GO:0044433 {is_inferred="true"} ! cytoplasmic vesicle part
 
 [Term]
-id: GO:0044844 ! meiotic interphase II
-is_a: GO:0051328 {is_inferred="true"} ! meiotic interphase
-is_a: GO:0098765 {is_inferred="true"} ! meiosis II cell cycle phase
-
-[Term]
 id: GO:0044853 ! plasma membrane raft
 is_a: GO:0098590 {is_inferred="true"} ! plasma membrane region
 
@@ -35884,10 +35895,6 @@
 is_a: GO:0072598 {is_inferred="true"} ! protein localization to chloroplast
 
 [Term]
-id: GO:0045037 ! protein import into chloroplast stroma
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
-
-[Term]
 id: GO:0045039 ! protein import into mitochondrial inner membrane
 is_a: GO:0070585 {is_inferred="true"} ! protein localization to mitochondrion
 is_a: GO:0072657 {is_inferred="true"} ! protein localization to membrane
@@ -35905,7 +35912,6 @@
 id: GO:0045041 ! protein import into mitochondrial intermembrane space
 is_a: GO:0070585 {is_inferred="true"} ! protein localization to mitochondrion
 is_a: GO:0072655 {is_inferred="true"} ! establishment of protein localization to mitochondrion
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 is_a: GO:1990542 {is_inferred="true"} ! mitochondrial transmembrane transport
 
 [Term]
@@ -36906,7 +36912,6 @@
 
 [Term]
 id: GO:0045476 ! nurse cell apoptotic process
-is_a: GO:0003006 {is_inferred="true"} ! developmental process involved in reproduction
 is_a: GO:0010623 {is_inferred="true"} ! programmed cell death involved in cell development
 is_a: GO:0022412 {is_inferred="true"} ! cellular process involved in reproduction in multicellular organism
 is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
@@ -43704,7 +43709,7 @@
 is_a: GO:0002832 {is_inferred="true"} ! negative regulation of response to biotic stimulus
 is_a: GO:0031348 {is_inferred="true"} ! negative regulation of defense response
 is_a: GO:0032102 {is_inferred="true"} ! negative regulation of response to external stimulus
-is_a: GO:0043901 {is_inferred="true"} ! negative regulation of multi-organism process
+is_a: GO:0048525 {is_inferred="true"} ! negative regulation of viral process
 is_a: GO:0050688 {is_inferred="true"} ! regulation of defense response to virus
 
 [Term]
@@ -43713,7 +43718,7 @@
 is_a: GO:0002831 {is_inferred="true"} ! regulation of response to biotic stimulus
 is_a: GO:0031347 {is_inferred="true"} ! regulation of defense response
 is_a: GO:0032101 {is_inferred="true"} ! regulation of response to external stimulus
-is_a: GO:0043900 {is_inferred="true"} ! regulation of multi-organism process
+is_a: GO:0050792 {is_inferred="true"} ! regulation of viral process
 
 [Term]
 id: GO:0050696 ! trichloroethylene catabolic process
@@ -44277,10 +44282,6 @@
 is_a: GO:0048871 {is_inferred="true"} ! multicellular organismal homeostasis
 
 [Term]
-id: GO:0050892 ! intestinal absorption
-is_a: GO:0022600 {is_inferred="true"} ! digestive system process
-
-[Term]
 id: GO:0050897 ! cobalt ion binding
 is_a: GO:0046914 {is_inferred="true"} ! transition metal ion binding
 
@@ -47747,7 +47748,6 @@
 [Term]
 id: GO:0060136 ! embryonic process involved in female pregnancy
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
-is_a: GO:0048609 {is_inferred="true"} ! multicellular organismal reproductive process
 
 [Term]
 id: GO:0060142 ! regulation of syncytium formation by plasma membrane fusion
@@ -48735,7 +48735,6 @@
 
 [Term]
 id: GO:0060530 ! smooth muscle cell differentiation involved in prostate glandular acinus development
-is_a: GO:0003006 {is_inferred="true"} ! developmental process involved in reproduction
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
 is_a: GO:0051145 {is_inferred="true"} ! smooth muscle cell differentiation
@@ -49233,7 +49232,6 @@
 
 [Term]
 id: GO:0060706 ! cell differentiation involved in embryonic placenta development
-is_a: GO:0003006 {is_inferred="true"} ! developmental process involved in reproduction
 is_a: GO:0030154 {is_inferred="true"} ! cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
@@ -49370,7 +49368,6 @@
 
 [Term]
 id: GO:0060742 ! epithelial cell differentiation involved in prostate gland development
-is_a: GO:0003006 {is_inferred="true"} ! developmental process involved in reproduction
 is_a: GO:0030855 {is_inferred="true"} ! epithelial cell differentiation
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
@@ -49902,10 +49899,6 @@
 is_a: GO:0042127 {is_inferred="true"} ! regulation of cell proliferation
 
 [Term]
-id: GO:0061009 ! common bile duct development
-is_a: GO:0035295 {is_inferred="true"} ! tube development
-
-[Term]
 id: GO:0061011 ! hepatic duct development
 is_a: GO:0061009 {is_inferred="true"} ! common bile duct development
 
@@ -50993,10 +50986,6 @@
 is_a: GO:0044702 {is_inferred="true"} ! single organism reproductive process
 
 [Term]
-id: GO:0061691 ! detoxification of hydrogen peroxide
-is_a: GO:0042743 {is_inferred="true"} ! hydrogen peroxide metabolic process
-
-[Term]
 id: GO:0061704 ! glycolytic process from sucrose
 is_a: GO:0005987 {is_inferred="true"} ! sucrose catabolic process
 
@@ -52233,7 +52222,6 @@
 
 [Term]
 id: GO:0070586 ! cell-cell adhesion involved in gastrulation
-is_a: GO:0016337 {is_inferred="true"} ! single organismal cell-cell adhesion
 is_a: GO:0098742 {is_inferred="true"} ! cell-cell adhesion via plasma-membrane adhesion molecules
 
 [Term]
@@ -53141,10 +53129,6 @@
 is_a: GO:0071025 {is_inferred="true"} ! RNA surveillance
 
 [Term]
-id: GO:0071050 ! snoRNA polyadenylation
-is_a: GO:0031126 {is_inferred="true"} ! snoRNA 3'-end processing
-
-[Term]
 id: GO:0071052 ! alpha9-beta1 integrin-ADAM1 complex
 is_a: GO:0098797 {is_inferred="true"} ! plasma membrane protein complex
 
@@ -54363,6 +54347,10 @@
 is_a: GO:0071229 {is_inferred="true"} ! cellular response to acid chemical
 
 [Term]
+id: GO:0071458 ! integral component of cytoplasmic side of endoplasmic reticulum membrane
+is_a: GO:0030176 {is_inferred="true"} ! integral component of endoplasmic reticulum membrane
+
+[Term]
 id: GO:0071462 ! cellular response to water stimulus
 is_a: GO:0009415 {is_inferred="true"} ! response to water
 is_a: GO:0071229 {is_inferred="true"} ! cellular response to acid chemical
@@ -54492,6 +54480,10 @@
 is_a: GO:0045229 {is_inferred="true"} ! external encapsulating structure organization
 
 [Term]
+id: GO:0071556 ! integral component of lumenal side of endoplasmic reticulum membrane
+is_a: GO:0030176 {is_inferred="true"} ! integral component of endoplasmic reticulum membrane
+
+[Term]
 id: GO:0071574 ! protein localization to medial cortex
 is_a: GO:0072741 {is_inferred="true"} ! protein localization to cell division site
 
@@ -54612,6 +54604,7 @@
 
 [Term]
 id: GO:0071627 ! integral component of fungal-type vacuolar membrane
+is_a: GO:0031166 {is_inferred="true"} ! integral component of vacuolar membrane
 is_a: GO:0071628 {is_inferred="true"} ! intrinsic component of fungal-type vacuolar membrane
 
 [Term]
@@ -55214,6 +55207,11 @@
 is_a: GO:0072698 {is_inferred="true"} ! protein localization to microtubule cytoskeleton
 
 [Term]
+id: GO:0071989 ! establishment of protein localization to spindle pole body
+is_a: GO:0071988 {is_inferred="true"} ! protein localization to spindle pole body
+is_a: GO:0072594 {is_inferred="true"} ! establishment of protein localization to organelle
+
+[Term]
 id: GO:0071990 ! maintenance of protein location to spindle pole body
 is_a: GO:0022402 {is_inferred="true"} ! cell cycle process
 
@@ -55917,7 +55915,6 @@
 id: GO:0072384 ! organelle transport along microtubule
 is_a: GO:0030705 {is_inferred="true"} ! cytoskeleton-dependent intracellular transport
 is_a: GO:0051656 {is_inferred="true"} ! establishment of organelle localization
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
@@ -55960,14 +55957,6 @@
 is_a: GO:0035556 {is_inferred="true"} ! intracellular signal transduction
 
 [Term]
-id: GO:0072397 ! detection of stimulus involved in cytokinesis checkpoint
-is_a: GO:0072412 {is_inferred="true"} ! detection of stimulus involved in mitotic cell cycle checkpoint
-
-[Term]
-id: GO:0072398 ! signal transduction involved in cytokinesis checkpoint
-is_a: GO:0072413 {is_inferred="true"} ! signal transduction involved in mitotic cell cycle checkpoint
-
-[Term]
 id: GO:0072400 ! detection of stimulus involved in mitotic DNA integrity checkpoint
 is_a: GO:0072412 {is_inferred="true"} ! detection of stimulus involved in mitotic cell cycle checkpoint
 
@@ -56192,10 +56181,6 @@
 is_a: GO:0006812 {is_inferred="true"} ! cation transport
 
 [Term]
-id: GO:0072520 ! seminiferous tubule development
-is_a: GO:0035295 {is_inferred="true"} ! tube development
-
-[Term]
 id: GO:0072521 ! purine-containing compound metabolic process
 is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
 is_a: GO:0046483 {is_inferred="true"} ! heterocycle metabolic process
@@ -57451,7 +57436,6 @@
 
 [Term]
 id: GO:0080162 ! intracellular auxin transport
-is_a: GO:0060919 {is_inferred="true"} ! auxin influx
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
@@ -58149,7 +58133,6 @@
 [Term]
 id: GO:0090110 ! cargo loading into COPII-coated vesicle
 is_a: GO:0051668 {is_inferred="true"} ! localization within membrane
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 is_a: GO:1902582 {is_inferred="true"} ! single-organism intracellular transport
 
 [Term]
@@ -58643,7 +58626,6 @@
 
 [Term]
 id: GO:0090250 ! cell-cell adhesion involved in establishment of planar polarity
-is_a: GO:0016337 {is_inferred="true"} ! single organismal cell-cell adhesion
 is_a: GO:0098742 {is_inferred="true"} ! cell-cell adhesion via plasma-membrane adhesion molecules
 
 [Term]
@@ -59230,6 +59212,11 @@
 is_a: GO:0098815 {is_inferred="true"} ! modulation of excitatory postsynaptic potential
 
 [Term]
+id: GO:0090401 ! viral-induced premature senescence
+is_a: GO:0044111 {is_inferred="true"} ! development involved in symbiotic interaction
+is_a: GO:0044764 {is_inferred="true"} ! multi-organism cellular process
+
+[Term]
 id: GO:0090407 ! organophosphate biosynthetic process
 is_a: GO:0019637 {is_inferred="true"} ! organophosphate metabolic process
 is_a: GO:1901576 {is_inferred="true"} ! organic substance biosynthetic process
@@ -60065,15 +60052,13 @@
 is_a: GO:0044422 {is_inferred="true"} ! organelle part
 
 [Term]
-id: GO:0097629 ! extrinsic component of omegasome membrane
-is_a: GO:0044444 {is_inferred="true"} ! cytoplasmic part
-
-[Term]
 id: GO:0097630 ! intrinsic component of omegasome membrane
-is_a: GO:0044444 {is_inferred="true"} ! cytoplasmic part
+is_a: GO:0031300 {is_inferred="true"} ! intrinsic component of organelle membrane
+is_a: GO:0044424 {is_inferred="true"} ! intracellular part
 
 [Term]
 id: GO:0097631 ! integral component of omegasome membrane
+is_a: GO:0031301 {is_inferred="true"} ! integral component of organelle membrane
 is_a: GO:0097630 {is_inferred="true"} ! intrinsic component of omegasome membrane
 
 [Term]
@@ -60082,10 +60067,12 @@
 
 [Term]
 id: GO:0097633 ! intrinsic component of pre-autophagosomal structure membrane
+is_a: GO:0031224 {is_inferred="true"} ! intrinsic component of membrane
 is_a: GO:0044444 {is_inferred="true"} ! cytoplasmic part
 
 [Term]
 id: GO:0097634 ! integral component of pre-autophagosomal structure membrane
+is_a: GO:0016021 {is_inferred="true"} ! integral component of membrane
 is_a: GO:0097633 {is_inferred="true"} ! intrinsic component of pre-autophagosomal structure membrane
 
 [Term]
@@ -60254,12 +60241,12 @@
 
 [Term]
 id: GO:0098540 ! lumenal side of trans-Golgi network transport vesicle membrane
-is_a: GO:0098547 {is_inferred="true"} ! lumenal side of Golgi membrane
+is_a: GO:0044431 {is_inferred="true"} ! Golgi apparatus part
 
 [Term]
 id: GO:0098541 ! cytoplasmic side of trans-Golgi network transport vesicle membrane
+is_a: GO:0044431 {is_inferred="true"} ! Golgi apparatus part
 is_a: GO:0098539 {is_inferred="true"} ! cytoplasmic side of transport vesicle membrane
-is_a: GO:0098548 {is_inferred="true"} ! cytoplasmic side of Golgi membrane
 
 [Term]
 id: GO:0098542 ! defense response to other organism
@@ -60308,7 +60295,7 @@
 [Term]
 id: GO:0098553 ! lumenal side of endoplasmic reticulum membrane
 is_a: GO:0044432 {is_inferred="true"} ! endoplasmic reticulum part
-is_a: GO:0098576 {is_inferred="true"} ! lumenal side of membrane
+is_a: GO:0098552 {is_inferred="true"} ! side of membrane
 
 [Term]
 id: GO:0098554 ! cytoplasmic side of endoplasmic reticulum membrane
@@ -60318,6 +60305,7 @@
 [Term]
 id: GO:0098555 ! lumenal side of rough endoplasmic reticulum membrane
 is_a: GO:0098553 {is_inferred="true"} ! lumenal side of endoplasmic reticulum membrane
+is_a: GO:0098576 {is_inferred="true"} ! lumenal side of membrane
 
 [Term]
 id: GO:0098556 ! cytoplasmic side of rough endoplasmic reticulum membrane
@@ -60332,6 +60320,7 @@
 id: GO:0098558 ! lumenal side of smooth endoplasmic reticulum membrane
 is_a: GO:0097425 {is_inferred="true"} ! smooth endoplasmic reticulum part
 is_a: GO:0098553 {is_inferred="true"} ! lumenal side of endoplasmic reticulum membrane
+is_a: GO:0098576 {is_inferred="true"} ! lumenal side of membrane
 
 [Term]
 id: GO:0098559 ! cytoplasmic side of early endosome membrane
@@ -60691,6 +60680,7 @@
 [Term]
 id: GO:0098752 ! integral component of the cytoplasmic side of the plasma membrane
 is_a: GO:0005887 {is_inferred="true"} ! integral component of plasma membrane
+is_a: GO:0031235 {is_inferred="true"} ! intrinsic component of the cytoplasmic side of the plasma membrane
 
 [Term]
 id: GO:0098753 ! anchored component of the cytoplasmic side of the plasma membrane
@@ -60697,14 +60687,6 @@
 is_a: GO:0046658 {is_inferred="true"} ! anchored component of plasma membrane
 
 [Term]
-id: GO:0098765 ! meiosis II cell cycle phase
-is_a: GO:0098762 {is_inferred="true"} ! meiotic cell cycle phase
-
-[Term]
-id: GO:0098768 ! meiotic prometaphase I
-is_a: GO:0098764 {is_inferred="true"} ! meiosis I cell cycle phase
-
-[Term]
 id: GO:0098771 ! inorganic ion homeostasis
 is_a: GO:0050801 {is_inferred="true"} ! ion homeostasis
 
@@ -63536,7 +63518,7 @@
 is_a: GO:0031349 {is_inferred="true"} ! positive regulation of defense response
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
 is_a: GO:0039533 {is_inferred="true"} ! regulation of MDA-5 signaling pathway
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
+is_a: GO:0048524 {is_inferred="true"} ! positive regulation of viral process
 is_a: GO:1902533 {is_inferred="true"} ! positive regulation of intracellular signal transduction
 
 [Term]
@@ -63546,7 +63528,7 @@
 is_a: GO:0031349 {is_inferred="true"} ! positive regulation of defense response
 is_a: GO:0032103 {is_inferred="true"} ! positive regulation of response to external stimulus
 is_a: GO:0039535 {is_inferred="true"} ! regulation of RIG-I signaling pathway
-is_a: GO:0043902 {is_inferred="true"} ! positive regulation of multi-organism process
+is_a: GO:0048524 {is_inferred="true"} ! positive regulation of viral process
 is_a: GO:1902533 {is_inferred="true"} ! positive regulation of intracellular signal transduction
 
 [Term]
@@ -63603,7 +63585,6 @@
 [Term]
 id: GO:1900262 ! regulation of DNA-directed DNA polymerase activity
 is_a: GO:0051338 {is_inferred="true"} ! regulation of transferase activity
-is_a: GO:0090329 {is_inferred="true"} ! regulation of DNA-dependent DNA replication
 is_a: GO:2000278 {is_inferred="true"} ! regulation of DNA biosynthetic process
 
 [Term]
@@ -70013,10 +69994,6 @@
 is_a: GO:2000639 {is_inferred="true"} ! negative regulation of SREBP signaling pathway
 
 [Term]
-id: GO:1901487 ! negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolic process in response to increased oxygen levels
-is_a: GO:1901486 {is_inferred="true"} ! negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolic process
-
-[Term]
 id: GO:1901488 ! positive regulation of SREBP signaling pathway by negative regulation of transcription factor catabolic process
 is_a: GO:0050789 {is_inferred="true"} ! regulation of biological process
 
@@ -70678,7 +70655,6 @@
 
 [Term]
 id: GO:1901619 ! tRNA methylation in response to nitrogen starvation
-is_a: GO:0030488 {is_inferred="true"} ! tRNA methylation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
 [Term]
@@ -73526,10 +73502,6 @@
 is_a: GO:2001244 {is_inferred="true"} ! positive regulation of intrinsic apoptotic signaling pathway
 
 [Term]
-id: GO:1902178 ! fibroblast growth factor receptor apoptotic signaling pathway
-is_a: GO:0008543 {is_inferred="true"} ! fibroblast growth factor receptor signaling pathway
-
-[Term]
 id: GO:1902179 ! verruculogen metabolic process
 is_a: GO:0006725 {is_inferred="true"} ! cellular aromatic compound metabolic process
 is_a: GO:0018904 {is_inferred="true"} ! ether metabolic process
@@ -74794,13 +74766,12 @@
 
 [Term]
 id: GO:1902440 ! protein localization to mitotic spindle pole body
-is_a: GO:0071988 {is_inferred="true"} ! protein localization to spindle pole body
 is_a: GO:1902480 {is_inferred="true"} ! protein localization to mitotic spindle
 
 [Term]
 id: GO:1902441 ! protein localization to meiotic spindle pole body
 is_a: GO:0022414 {is_inferred="true"} ! reproductive process
-is_a: GO:0071988 {is_inferred="true"} ! protein localization to spindle pole body
+is_a: GO:0072698 {is_inferred="true"} ! protein localization to microtubule cytoskeleton
 
 [Term]
 id: GO:1902442 ! regulation of ripoptosome assembly involved in necroptotic process
@@ -75246,12 +75217,12 @@
 
 [Term]
 id: GO:1902542 ! regulation of protein localization to mitotic spindle pole body
-is_a: GO:1902363 {is_inferred="true"} ! regulation of protein localization to spindle pole body
+is_a: GO:1903827 {is_inferred="true"} ! regulation of cellular protein localization
 
 [Term]
 id: GO:1902543 ! negative regulation of protein localization to mitotic spindle pole body
-is_a: GO:1902364 {is_inferred="true"} ! negative regulation of protein localization to spindle pole body
 is_a: GO:1902542 {is_inferred="true"} ! regulation of protein localization to mitotic spindle pole body
+is_a: GO:1903828 {is_inferred="true"} ! negative regulation of cellular protein localization
 
 [Term]
 id: GO:1902544 ! regulation of DNA N-glycosylase activity
@@ -75432,11 +75403,13 @@
 id: GO:1902582 ! single-organism intracellular transport
 is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
 is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
+is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 
 [Term]
 id: GO:1902583 ! multi-organism intracellular transport
 is_a: GO:0044766 {is_inferred="true"} ! multi-organism transport
 is_a: GO:0046907 {is_inferred="true"} ! intracellular transport
+is_a: GO:1902581 {is_inferred="true"} ! multi-organism cellular localization
 
 [Term]
 id: GO:1902584 ! positive regulation of response to water deprivation
@@ -79077,7 +79050,7 @@
 
 [Term]
 id: GO:1903349 ! omegasome membrane
-is_a: GO:0044444 {is_inferred="true"} ! cytoplasmic part
+is_a: GO:0044424 {is_inferred="true"} ! intracellular part
 
 [Term]
 id: GO:1903350 ! response to dopamine
@@ -79552,7 +79525,6 @@
 id: GO:1903445 ! protein transport from ciliary membrane to plasma membrane
 is_a: GO:0032594 {is_inferred="true"} ! protein transport within lipid bilayer
 is_a: GO:0072657 {is_inferred="true"} ! protein localization to membrane
-is_a: GO:0090002 {is_inferred="true"} ! establishment of protein localization to plasma membrane
 is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
 
 [Term]
@@ -89291,6 +89263,7 @@
 
 [Term]
 id: GO:1990673 ! intrinsic component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane
+is_a: GO:0031300 {is_inferred="true"} ! intrinsic component of organelle membrane
 is_a: GO:0044444 {is_inferred="true"} ! cytoplasmic part
 
 [Term]
@@ -89312,18 +89285,22 @@
 [Term]
 id: GO:1990701 ! integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane
 is_a: GO:0031301 {is_inferred="true"} ! integral component of organelle membrane
+is_a: GO:1990673 {is_inferred="true"} ! intrinsic component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane
 
 [Term]
 id: GO:1990702 ! integral component of Golgi cis cisterna membrane
 is_a: GO:0030173 {is_inferred="true"} ! integral component of Golgi membrane
+is_a: GO:1990693 {is_inferred="true"} ! intrinsic component of Golgi cis cisterna membrane
 
 [Term]
 id: GO:1990703 ! integral component of Golgi medial cisterna membrane
 is_a: GO:0030173 {is_inferred="true"} ! integral component of Golgi membrane
+is_a: GO:1990694 {is_inferred="true"} ! intrinsic component of Golgi medial cisterna membrane
 
 [Term]
 id: GO:1990704 ! integral component of Golgi trans cisterna membrane
 is_a: GO:0030173 {is_inferred="true"} ! integral component of Golgi membrane
+is_a: GO:1990695 {is_inferred="true"} ! intrinsic component of Golgi trans cisterna membrane
 
 [Term]
 id: GO:1990707 ! nuclear subtelomeric heterochromatin
@@ -89464,10 +89441,8 @@
 
 [Term]
 id: GO:1990852 ! protein transport along microtubule to spindle pole body
-is_a: GO:0071988 {is_inferred="true"} ! protein localization to spindle pole body
 is_a: GO:0071989 {is_inferred="true"} ! establishment of protein localization to spindle pole body
 is_a: GO:0098840 {is_inferred="true"} ! protein transport along microtubule
-is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 
 [Term]
 id: GO:1990854 ! vacuole-ER tethering
@@ -89475,6 +89450,7 @@
 
 [Term]
 id: GO:1990862 ! nuclear membrane complex Bqt3-Bqt4
+is_a: GO:0044453 {is_inferred="true"} ! nuclear membrane part
 is_a: GO:0098796 {is_inferred="true"} ! membrane protein complex
 
 [Term]
@@ -89537,7 +89513,8 @@
 
 [Term]
 id: GO:1990954 ! establishment of protein localization to meiotic spindle pole body
-is_a: GO:0022414 {is_inferred="true"} ! reproductive process
+is_a: GO:0071989 {is_inferred="true"} ! establishment of protein localization to spindle pole body
+is_a: GO:1902441 {is_inferred="true"} ! protein localization to meiotic spindle pole body
 
 [Term]
 id: GO:1990957 ! NPHP complex
@@ -89687,7 +89664,6 @@
 
 [Term]
 id: GO:2000026 ! regulation of multicellular organismal development
-is_a: GO:0050793 {is_inferred="true"} ! regulation of developmental process
 is_a: GO:0051239 {is_inferred="true"} ! regulation of multicellular organismal process
 
 [Term]
------------------------------------------------------------------------
r34114 | termgenie | 2016-06-23 23:33:06 -0700 (Thu, 23 Jun 2016) | 4 lines

TermGenie commit for user: sl reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34114)
+++ go_inferences.obo	(working copy)
@@ -88577,6 +88577,20 @@
 is_a: GO:0034390 {is_inferred="true"} ! smooth muscle cell apoptotic process
 
 [Term]
+id: GO:1905289 ! regulation of CAMKK-AMPK signaling cascade
+is_a: GO:0050848 {is_inferred="true"} ! regulation of calcium-mediated signaling
+
+[Term]
+id: GO:1905290 ! negative regulation of CAMKK-AMPK signaling cascade
+is_a: GO:0050849 {is_inferred="true"} ! negative regulation of calcium-mediated signaling
+is_a: GO:1905289 {is_inferred="true"} ! regulation of CAMKK-AMPK signaling cascade
+
+[Term]
+id: GO:1905291 ! positive regulation of CAMKK-AMPK signaling cascade
+is_a: GO:0050850 {is_inferred="true"} ! positive regulation of calcium-mediated signaling
+is_a: GO:1905289 {is_inferred="true"} ! regulation of CAMKK-AMPK signaling cascade
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34106 | cjm | 2016-06-23 10:51:21 -0700 (Thu, 23 Jun 2016) | 1 line

removed extraneous whitespace - checks are picky about this

changes in entailments

------------------------------------------------------------------------
r34099 | termgenie | 2016-06-23 07:03:49 -0700 (Thu, 23 Jun 2016) | 2 lines

TermGenie commit for user: rph reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34099)
+++ go_inferences.obo	(working copy)
@@ -88573,6 +88573,10 @@
 is_a: GO:0010971 {is_inferred="true"} ! positive regulation of G2/M transition of mitotic cell cycle
 
 [Term]
+id: GO:1905288 ! vascular associated smooth muscle cell apoptotic process
+is_a: GO:0034390 {is_inferred="true"} ! smooth muscle cell apoptotic process
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
 
------------------------------------------------------------------------
r34092 | termgenie | 2016-06-22 12:30:13 -0700 (Wed, 22 Jun 2016) | 2 lines

TermGenie commit for user: hjd reviewed by tb

changes in entailments

------------------------------------------------------------------------
r34090 | termgenie | 2016-06-22 12:02:37 -0700 (Wed, 22 Jun 2016) | 2 lines

TermGenie commit for user: bf reviewed by tb

changes in entailments

------------------------------------------------------------------------
r34088 | termgenie | 2016-06-22 11:53:50 -0700 (Wed, 22 Jun 2016) | 2 lines

TermGenie commit for user: hjd reviewed by tb

changes in entailments

------------------------------------------------------------------------
r34083 | termgenie | 2016-06-22 10:06:24 -0700 (Wed, 22 Jun 2016) | 2 lines

TermGenie commit for user: bf reviewed by tb

changes in entailments

------------------------------------------------------------------------
r34083 | termgenie | 2016-06-22 10:06:24 -0700 (Wed, 22 Jun 2016) | 2 lines

TermGenie commit for user: bf reviewed by tb

changes in entailments

------------------------------------------------------------------------
r34082 | termgenie | 2016-06-22 10:00:59 -0700 (Wed, 22 Jun 2016) | 2 lines

TermGenie commit for user: bf reviewed by tb

changes in entailments

------------------------------------------------------------------------
r34074 | tberardi | 2016-06-21 17:24:20 -0700 (Tue, 21 Jun 2016) | 1 line

adding in parents for TGFF generated protein complex terms

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34074)
+++ go_inferences.obo	(working copy)
@@ -89534,6 +89534,16 @@
 is_a: GO:0043170 {is_inferred="true"} ! macromolecule metabolic process
 
 [Term]
+id: GO:1990971 ! EMILIN complex
+is_a: GO:0044420 {is_inferred="true"} ! extracellular matrix component
+is_a: GO:0098637 {is_inferred="true"} ! protein complex involved in cell-matrix adhesion
+
+[Term]
+id: GO:1990972 ! multimerin complex
+is_a: GO:0044420 {is_inferred="true"} ! extracellular matrix component
+is_a: GO:0098637 {is_inferred="true"} ! protein complex involved in cell-matrix adhesion
+
+[Term]
 id: GO:2000001 ! regulation of DNA damage checkpoint
 is_a: GO:1901976 {is_inferred="true"} ! regulation of cell cycle checkpoint
 is_a: GO:2001020 {is_inferred="true"} ! regulation of response to DNA damage stimulus
------------------------------------------------------------------------
r34068 | termgenie | 2016-06-21 14:46:12 -0700 (Tue, 21 Jun 2016) | 2 lines

TermGenie commit for user: al reviewed by tb

changes in entailments

NOTE: a large section of this diff is spurious, as we change the pipeline to avoid adding dupes into go_inferences.obo

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34068)
+++ go_inferences.obo	(working copy)

SPURIOUS DIFF DELETED

------------------------------------------------------------------------
r34063 | tberardi | 2016-06-21 14:12:37 -0700 (Tue, 21 Jun 2016) | 1 line

test commit after P5 edit, one synonym added

changes in entailments

------------------------------------------------------------------------
r34056 | termgenie | 2016-06-20 13:02:59 -0700 (Mon, 20 Jun 2016) | 4 lines

TermGenie commit for user: bc reviewed by tb

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34056)
+++ go_inferences.obo	(working copy)
@@ -135409,6 +135409,7 @@
 id: GO:0061132 ! pancreas induction
 is_a: GO:0001759 {is_inferred="true"} ! organ induction
 is_a: GO:0060688 {is_inferred="true"} ! regulation of morphogenesis of a branching structure
+is_a: GO:1905278 {is_inferred="true"} ! positive regulation of epithelial tube formation
 
 [Term]
 id: GO:0061133 ! endopeptidase activator activity
@@ -147986,6 +147987,7 @@
 id: GO:0072106 ! regulation of ureteric bud formation
 is_a: GO:0045995 {is_inferred="true"} ! regulation of embryonic development
 is_a: GO:0061217 {is_inferred="true"} ! regulation of mesonephros development
+is_a: GO:1905276 {is_inferred="true"} ! regulation of epithelial tube formation
 is_a: GO:2000027 {is_inferred="true"} ! regulation of organ morphogenesis
 
 [Term]
@@ -147993,6 +147995,7 @@
 is_a: GO:0040019 {is_inferred="true"} ! positive regulation of embryonic development
 is_a: GO:0061213 {is_inferred="true"} ! positive regulation of mesonephros development
 is_a: GO:0072106 {is_inferred="true"} ! regulation of ureteric bud formation
+is_a: GO:1905278 {is_inferred="true"} ! positive regulation of epithelial tube formation
 
 [Term]
 id: GO:0072108 ! positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
@@ -155035,6 +155038,7 @@
 is_a: GO:0045995 {is_inferred="true"} ! regulation of embryonic development
 is_a: GO:0051960 {is_inferred="true"} ! regulation of nervous system development
 is_a: GO:0090175 {is_inferred="true"} ! regulation of establishment of planar polarity
+is_a: GO:1905276 {is_inferred="true"} ! regulation of epithelial tube formation
 
 [Term]
 id: GO:0090179 ! planar cell polarity pathway involved in neural tube closure
@@ -191175,6 +191179,58 @@
 is_a: GO:0030182 {is_inferred="true"} ! neuron differentiation
 
 [Term]
+id: GO:1905276 ! regulation of epithelial tube formation
+is_a: GO:0022603 {is_inferred="true"} ! regulation of anatomical structure morphogenesis
+is_a: GO:2000026 {is_inferred="true"} ! regulation of multicellular organismal development
+
+[Term]
+id: GO:1905277 ! negative regulation of epithelial tube formation
+is_a: GO:0051093 {is_inferred="true"} ! negative regulation of developmental process
+is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
+is_a: GO:1905276 {is_inferred="true"} ! regulation of epithelial tube formation
+
+[Term]
+id: GO:1905278 ! positive regulation of epithelial tube formation
+is_a: GO:0051094 {is_inferred="true"} ! positive regulation of developmental process
+is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
+is_a: GO:1905276 {is_inferred="true"} ! regulation of epithelial tube formation
+
+[Term]
+id: GO:1905279 ! regulation of retrograde transport, endosome to Golgi
+is_a: GO:0060627 {is_inferred="true"} ! regulation of vesicle-mediated transport
+is_a: GO:1903335 {is_inferred="true"} ! regulation of vacuolar transport
+is_a: GO:1903649 {is_inferred="true"} ! regulation of cytoplasmic transport
+
+[Term]
+id: GO:1905280 ! negative regulation of retrograde transport, endosome to Golgi
+is_a: GO:1903336 {is_inferred="true"} ! negative regulation of vacuolar transport
+is_a: GO:1903650 {is_inferred="true"} ! negative regulation of cytoplasmic transport
+is_a: GO:1905279 {is_inferred="true"} ! regulation of retrograde transport, endosome to Golgi
+
+[Term]
+id: GO:1905281 ! positive regulation of retrograde transport, endosome to Golgi
+is_a: GO:1903337 {is_inferred="true"} ! positive regulation of vacuolar transport
+is_a: GO:1903651 {is_inferred="true"} ! positive regulation of cytoplasmic transport
+is_a: GO:1905279 {is_inferred="true"} ! regulation of retrograde transport, endosome to Golgi
+
+[Term]
+id: GO:1905282 ! regulation of epidermal growth factor receptor signaling pathway involved in heart process
+is_a: GO:0042058 {is_inferred="true"} ! regulation of epidermal growth factor receptor signaling pathway
+is_a: GO:0044057 {is_inferred="true"} ! regulation of system process
+
+[Term]
+id: GO:1905283 ! negative regulation of epidermal growth factor receptor signaling pathway involved in heart process
+is_a: GO:0042059 {is_inferred="true"} ! negative regulation of epidermal growth factor receptor signaling pathway
+is_a: GO:0051241 {is_inferred="true"} ! negative regulation of multicellular organismal process
+is_a: GO:1905282 {is_inferred="true"} ! regulation of epidermal growth factor receptor signaling pathway involved in heart process
+
+[Term]
+id: GO:1905284 ! positive regulation of epidermal growth factor receptor signaling pathway involved in heart process
+is_a: GO:0045742 {is_inferred="true"} ! positive regulation of epidermal growth factor receptor signaling pathway
+is_a: GO:0051240 {is_inferred="true"} ! positive regulation of multicellular organismal process
+is_a: GO:1905282 {is_inferred="true"} ! regulation of epidermal growth factor receptor signaling pathway involved in heart process
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0019538 {is_inferred="true"} ! protein metabolic process
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
@@ -195881,6 +195937,7 @@
 id: GO:2000168 ! negative regulation of planar cell polarity pathway involved in neural tube closure
 is_a: GO:0045992 {is_inferred="true"} ! negative regulation of embryonic development
 is_a: GO:0051961 {is_inferred="true"} ! negative regulation of nervous system development
+is_a: GO:1905277 {is_inferred="true"} ! negative regulation of epithelial tube formation
 is_a: GO:2000051 {is_inferred="true"} ! negative regulation of non-canonical Wnt signaling pathway
 is_a: GO:2000167 {is_inferred="true"} ! regulation of planar cell polarity pathway involved in neural tube closure
 
@@ -198611,6 +198668,7 @@
 is_a: GO:0040037 {is_inferred="true"} ! negative regulation of fibroblast growth factor receptor signaling pathway
 is_a: GO:0045992 {is_inferred="true"} ! negative regulation of embryonic development
 is_a: GO:0061218 {is_inferred="true"} ! negative regulation of mesonephros development
+is_a: GO:1905277 {is_inferred="true"} ! negative regulation of epithelial tube formation
 is_a: GO:2000702 {is_inferred="true"} ! regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
 
 [Term]
@@ -198776,6 +198834,7 @@
 is_a: GO:0009968 {is_inferred="true"} ! negative regulation of signal transduction
 is_a: GO:0045992 {is_inferred="true"} ! negative regulation of embryonic development
 is_a: GO:0061218 {is_inferred="true"} ! negative regulation of mesonephros development
+is_a: GO:1905277 {is_inferred="true"} ! negative regulation of epithelial tube formation
 is_a: GO:2000733 {is_inferred="true"} ! regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
 
 [Term]
------------------------------------------------------------------------
r34051 | davidos | 2016-06-20 06:02:51 -0700 (Mon, 20 Jun 2016) | 1 line

Some cleanup in the transport branch - testing out ease of automating given new GO pipeline.

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34051)
+++ go_inferences.obo	(working copy)
@@ -41560,7 +41560,6 @@
 
 [Term]
 id: GO:0015837 ! amine transport
-is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
 is_a: GO:0071702 {is_inferred="true"} ! organic substance transport
 is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
@@ -69879,7 +69878,7 @@
 [Term]
 id: GO:0032975 ! amino acid transmembrane import into vacuole
 is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
-is_a: GO:0044745 {is_inferred="true"} ! amino acid transmembrane import
+is_a: GO:0043090 {is_inferred="true"} ! amino acid import
 
 [Term]
 id: GO:0032976 ! release of matrix enzymes from mitochondria
@@ -80351,7 +80350,6 @@
 id: GO:0035377 ! transepithelial water transport
 is_a: GO:0006833 {is_inferred="true"} ! water transport
 is_a: GO:0042045 {is_inferred="true"} ! epithelial fluid transport
-is_a: GO:0070633 {is_inferred="true"} ! transepithelial transport
 
 [Term]
 id: GO:0035378 ! carbon dioxide transmembrane transport
@@ -84180,8 +84178,9 @@
 
 [Term]
 id: GO:0036249 ! cadmium ion import into vacuole
+is_a: GO:0000041 {is_inferred="true"} ! transition metal ion transport
 is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
-is_a: GO:0070574 {is_inferred="true"} ! cadmium ion transmembrane transport
+is_a: GO:0098662 {is_inferred="true"} ! inorganic cation transmembrane transport
 
 [Term]
 id: GO:0036250 ! peroxisome transport along microtubule
@@ -87706,7 +87705,7 @@
 [Term]
 id: GO:0042045 ! epithelial fluid transport
 is_a: GO:0042044 {is_inferred="true"} ! fluid transport
-is_a: GO:0055085 {is_inferred="true"} ! transmembrane transport
+is_a: GO:0070633 {is_inferred="true"} ! transepithelial transport
 
 [Term]
 id: GO:0042046 ! W-molybdopterin cofactor metabolic process
@@ -91438,7 +91437,6 @@
 
 [Term]
 id: GO:0042886 ! amide transport
-is_a: GO:0044765 {is_inferred="true"} ! single-organism transport
 is_a: GO:0071705 {is_inferred="true"} ! nitrogen compound transport
 
 [Term]
@@ -156348,7 +156346,7 @@
 [Term]
 id: GO:0090453 ! aspartate transmembrane import into vacuole
 is_a: GO:0015810 {is_inferred="true"} ! aspartate transport
-is_a: GO:0032975 {is_inferred="true"} ! amino acid transmembrane import into vacuole
+is_a: GO:0034486 {is_inferred="true"} ! vacuolar transmembrane transport
 is_a: GO:0098656 {is_inferred="true"} ! anion transmembrane transport
 
 [Term]
@@ -193479,6 +193477,7 @@
 
 [Term]
 id: GO:1990573 ! potassium ion import across plasma membrane
+is_a: GO:0071805 {is_inferred="true"} ! potassium ion transmembrane transport
 is_a: GO:0098739 {is_inferred="true"} ! import across plasma membrane
 
 [Term]
@@ -193552,7 +193551,7 @@
 
 [Term]
 id: GO:1990591 ! asparagine transmembrane import into vacuole
-is_a: GO:0032975 {is_inferred="true"} ! amino acid transmembrane import into vacuole
+is_a: GO:0034487 {is_inferred="true"} ! vacuolar amino acid transmembrane transport
 is_a: GO:0090469 {is_inferred="true"} ! asparagine import
 is_a: GO:1903713 {is_inferred="true"} ! asparagine transmembrane transport
 
------------------------------------------------------------------------
r34049 | termgenie | 2016-06-20 02:17:55 -0700 (Mon, 20 Jun 2016) | 2 lines

TermGenie commit for user: sp reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34049)
+++ go_inferences.obo	(working copy)
@@ -195014,6 +195014,11 @@
 is_a: GO:0016831 {is_inferred="true"} ! carboxy-lyase activity
 
 [Term]
+id: GO:1990966 ! ATP generation from poly-ADP-D-ribose
+is_a: GO:0043170 {is_inferred="true"} ! macromolecule metabolic process
+is_a: GO:0046034 {is_inferred="true"} ! ATP metabolic process
+
+[Term]
 id: GO:2000001 ! regulation of DNA damage checkpoint
 is_a: GO:1901976 {is_inferred="true"} ! regulation of cell cycle checkpoint
 is_a: GO:2001020 {is_inferred="true"} ! regulation of response to DNA damage stimulus
------------------------------------------------------------------------
r34029 | termgenie | 2016-06-19 12:23:22 -0700 (Sun, 19 Jun 2016) | 4 lines

TermGenie commit for user: als reviewed by pr

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34029)
+++ go_inferences.obo	(working copy)
@@ -56034,8 +56034,9 @@
 
 [Term]
 id: GO:0021905 ! forebrain-midbrain boundary formation
+is_a: GO:0044767 {is_inferred="true"} ! single-organism developmental process
+is_a: GO:0048646 {is_inferred="true"} ! anatomical structure formation involved in morphogenesis
 is_a: GO:0048856 {is_inferred="true"} ! anatomical structure development
-is_a: GO:0048859 {is_inferred="true"} ! formation of anatomical boundary
 
 [Term]
 id: GO:0021906 ! hindbrain-spinal cord boundary formation
@@ -132663,7 +132664,6 @@
 [Term]
 id: GO:0060532 ! bronchus cartilage development
 is_a: GO:0051216 {is_inferred="true"} ! cartilage development
-is_a: GO:0061448 {is_inferred="true"} ! connective tissue development
 
 [Term]
 id: GO:0060533 ! bronchus cartilage morphogenesis
@@ -190952,7 +190952,7 @@
 
 [Term]
 id: GO:1905225 ! response to thyrotropin-releasing hormone
-is_a: GO:0050896 {is_inferred="true"} ! response to stimulus
+is_a: GO:0043434 {is_inferred="true"} ! response to peptide hormone
 
 [Term]
 id: GO:1905226 ! regulation of adhesion of symbiont to host epithelial cell
@@ -190970,16 +190970,16 @@
 
 [Term]
 id: GO:1905229 ! cellular response to thyrotropin-releasing hormone
-is_a: GO:0070887 {is_inferred="true"} ! cellular response to chemical stimulus
+is_a: GO:0071375 {is_inferred="true"} ! cellular response to peptide hormone stimulus
 is_a: GO:1905225 {is_inferred="true"} ! response to thyrotropin-releasing hormone
 
 [Term]
 id: GO:1905230 ! response to borneol
-is_a: GO:0050896 {is_inferred="true"} ! response to stimulus
+is_a: GO:0033993 {is_inferred="true"} ! response to lipid
 
 [Term]
 id: GO:1905231 ! cellular response to borneol
-is_a: GO:0070887 {is_inferred="true"} ! cellular response to chemical stimulus
+is_a: GO:0071396 {is_inferred="true"} ! cellular response to lipid
 is_a: GO:1905230 {is_inferred="true"} ! response to borneol
 
 [Term]
@@ -191033,11 +191033,13 @@
 
 [Term]
 id: GO:1905242 ! response to 3,3',5-triiodo-L-thyronine
-is_a: GO:0050896 {is_inferred="true"} ! response to stimulus
+is_a: GO:0014070 {is_inferred="true"} ! response to organic cyclic compound
+is_a: GO:0043200 {is_inferred="true"} ! response to amino acid
 
 [Term]
 id: GO:1905243 ! cellular response to 3,3',5-triiodo-L-thyronine
-is_a: GO:0070887 {is_inferred="true"} ! cellular response to chemical stimulus
+is_a: GO:0071230 {is_inferred="true"} ! cellular response to amino acid stimulus
+is_a: GO:0071407 {is_inferred="true"} ! cellular response to organic cyclic compound
 is_a: GO:1905242 {is_inferred="true"} ! response to 3,3',5-triiodo-L-thyronine
 
 [Term]
@@ -191113,16 +191115,16 @@
 
 [Term]
 id: GO:1905264 ! blasticidin S metabolic process
-is_a: GO:0008152 {is_inferred="true"} ! metabolic process
+is_a: GO:0006213 {is_inferred="true"} ! pyrimidine nucleoside metabolic process
 
 [Term]
 id: GO:1905265 ! blasticidin S catabolic process
-is_a: GO:0009056 {is_inferred="true"} ! catabolic process
+is_a: GO:0046135 {is_inferred="true"} ! pyrimidine nucleoside catabolic process
 is_a: GO:1905264 {is_inferred="true"} ! blasticidin S metabolic process
 
 [Term]
 id: GO:1905266 ! blasticidin S biosynthetic process
-is_a: GO:0009058 {is_inferred="true"} ! biosynthetic process
+is_a: GO:0046134 {is_inferred="true"} ! pyrimidine nucleoside biosynthetic process
 is_a: GO:1905264 {is_inferred="true"} ! blasticidin S metabolic process
 
 [Term]
@@ -191146,12 +191148,33 @@
 is_a: GO:0021895 {is_inferred="true"} ! cerebral cortex neuron differentiation
 
 [Term]
+id: GO:1905271 ! regulation of proton-transporting ATP synthase activity, rotational mechanism
+is_a: GO:0010155 {is_inferred="true"} ! regulation of proton transport
+is_a: GO:0032412 {is_inferred="true"} ! regulation of ion transmembrane transporter activity
+is_a: GO:0043462 {is_inferred="true"} ! regulation of ATPase activity
+is_a: GO:1904062 {is_inferred="true"} ! regulation of cation transmembrane transport
+
+[Term]
+id: GO:1905272 ! negative regulation of proton-transporting ATP synthase activity, rotational mechanism
+is_a: GO:0032413 {is_inferred="true"} ! negative regulation of ion transmembrane transporter activity
+is_a: GO:0032780 {is_inferred="true"} ! negative regulation of ATPase activity
+is_a: GO:1904063 {is_inferred="true"} ! negative regulation of cation transmembrane transport
+is_a: GO:1905271 {is_inferred="true"} ! regulation of proton-transporting ATP synthase activity, rotational mechanism
+
+[Term]
+id: GO:1905273 ! positive regulation of proton-transporting ATP synthase activity, rotational mechanism
+is_a: GO:0032414 {is_inferred="true"} ! positive regulation of ion transmembrane transporter activity
+is_a: GO:0032781 {is_inferred="true"} ! positive regulation of ATPase activity
+is_a: GO:1904064 {is_inferred="true"} ! positive regulation of cation transmembrane transport
+is_a: GO:1905271 {is_inferred="true"} ! regulation of proton-transporting ATP synthase activity, rotational mechanism
+
+[Term]
 id: GO:1905274 ! regulation of modification of postsynaptic actin cytoskeleton
 is_a: GO:1905244 {is_inferred="true"} ! regulation of modification of synaptic structure
 
 [Term]
 id: GO:1905275 ! Rohon-Beard neuron differentiation
-is_a: GO:0030154 {is_inferred="true"} ! cell differentiation
+is_a: GO:0030182 {is_inferred="true"} ! neuron differentiation
 
 [Term]
 id: GO:1990000 ! amyloid fibril formation
------------------------------------------------------------------------
r34011 | davidos | 2016-06-17 09:47:51 -0700 (Fri, 17 Jun 2016) | 1 line

Fixing errors in EC defs adding in previous commit - these were causing false equivalence between named classes

changes in entailments

------------------------------------------------------------------------
r34011 | davidos | 2016-06-17 09:47:51 -0700 (Fri, 17 Jun 2016) | 1 line

Fixing errors in EC defs adding in previous commit - these were causing false equivalence between named classes

changes in entailments

Index: go_inferences.obo
===================================================================
--- go_inferences.obo	(revision 34011)
+++ go_inferences.obo	(working copy)
@@ -32947,10 +32947,9 @@
 
 [Term]
 id: GO:0009997 ! negative regulation of cardioblast cell fate specification
-is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
 is_a: GO:0042686 {is_inferred="true"} ! regulation of cardioblast cell fate specification
-is_a: GO:1905208 {is_inferred="true"} ! negative regulation of cardiocyte differentiation
-is_a: GO:2000737 {is_inferred="true"} ! negative regulation of stem cell differentiation
+is_a: GO:0051892 {is_inferred="true"} ! negative regulation of cardioblast differentiation
+is_a: GO:2000044 {is_inferred="true"} ! negative regulation of cardiac cell fate specification
 
 [Term]
 id: GO:0009998 ! negative regulation of retinal cone cell fate specification
@@ -90512,9 +90511,8 @@
 
 [Term]
 id: GO:0042686 ! regulation of cardioblast cell fate specification
-is_a: GO:0042659 {is_inferred="true"} ! regulation of cell fate specification
-is_a: GO:1905207 {is_inferred="true"} ! regulation of cardiocyte differentiation
-is_a: GO:2000736 {is_inferred="true"} ! regulation of stem cell differentiation
+is_a: GO:0051890 {is_inferred="true"} ! regulation of cardioblast differentiation
+is_a: GO:2000043 {is_inferred="true"} ! regulation of cardiac cell fate specification
 
 [Term]
 id: GO:0042688 ! crystal cell differentiation
@@ -125125,6 +125123,23 @@
 is_a: GO:0051887 {is_inferred="true"} ! regulation of exogen
 
 [Term]
+id: GO:0051890 ! regulation of cardioblast differentiation
+is_a: GO:1905207 {is_inferred="true"} ! regulation of cardiocyte differentiation
+is_a: GO:2000736 {is_inferred="true"} ! regulation of stem cell differentiation
+
+[Term]
+id: GO:0051891 ! positive regulation of cardioblast differentiation
+is_a: GO:0051890 {is_inferred="true"} ! regulation of cardioblast differentiation
+is_a: GO:1905209 {is_inferred="true"} ! positive regulation of cardiocyte differentiation
+is_a: GO:2000738 {is_inferred="true"} ! positive regulation of stem cell differentiation
+
+[Term]
+id: GO:0051892 ! negative regulation of cardioblast differentiation
+is_a: GO:0051890 {is_inferred="true"} ! regulation of cardioblast differentiation
+is_a: GO:1905208 {is_inferred="true"} ! negative regulation of cardiocyte differentiation
+is_a: GO:2000737 {is_inferred="true"} ! negative regulation of stem cell differentiation
+
+[Term]
 id: GO:0051893 ! regulation of focal adhesion assembly
 is_a: GO:0001952 {is_inferred="true"} ! regulation of cell-matrix adhesion
 is_a: GO:0090109 {is_inferred="true"} ! regulation of cell-substrate junction assembly
@@ -129680,26 +129695,20 @@
 
 [Term]
 id: GO:0055018 ! regulation of cardiac muscle fiber development
-is_a: GO:0051153 {is_inferred="true"} ! regulation of striated muscle cell differentiation
-is_a: GO:0055024 {is_inferred="true"} ! regulation of cardiac muscle tissue development
 is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
-is_a: GO:1905207 {is_inferred="true"} ! regulation of cardiocyte differentiation
+is_a: GO:2000725 {is_inferred="true"} ! regulation of cardiac muscle cell differentiation
 
 [Term]
 id: GO:0055019 ! negative regulation of cardiac muscle fiber development
 is_a: GO:0010721 {is_inferred="true"} ! negative regulation of cell development
-is_a: GO:0051154 {is_inferred="true"} ! negative regulation of striated muscle cell differentiation
 is_a: GO:0055018 {is_inferred="true"} ! regulation of cardiac muscle fiber development
-is_a: GO:0055026 {is_inferred="true"} ! negative regulation of cardiac muscle tissue development
-is_a: GO:1905208 {is_inferred="true"} ! negative regulation of cardiocyte differentiation
+is_a: GO:2000726 {is_inferred="true"} ! negative regulation of cardiac muscle cell differentiation
 
 [Term]
 id: GO:0055020 ! positive regulation of cardiac muscle fiber development
 is_a: GO:0010720 {is_inferred="true"} ! positive regulation of cell development
-is_a: GO:0051155 {is_inferred="true"} ! positive regulation of striated muscle cell differentiation
 is_a: GO:0055018 {is_inferred="true"} ! regulation of cardiac muscle fiber development
-is_a: GO:0055025 {is_inferred="true"} ! positive regulation of cardiac muscle tissue development
-is_a: GO:1905209 {is_inferred="true"} ! positive regulation of cardiocyte differentiation
+is_a: GO:2000727 {is_inferred="true"} ! positive regulation of cardiac muscle cell differentiation
 
 [Term]
 id: GO:0055021 ! regulation of cardiac muscle tissue growth
@@ -134995,10 +135004,9 @@
 id: GO:0061050 ! regulation of cell growth involved in cardiac muscle cell development
 is_a: GO:0001558 {is_inferred="true"} ! regulation of cell growth
 is_a: GO:0010611 {is_inferred="true"} ! regulation of cardiac muscle hypertrophy
-is_a: GO:0051153 {is_inferred="true"} ! regulation of striated muscle cell differentiation
 is_a: GO:0055021 {is_inferred="true"} ! regulation of cardiac muscle tissue growth
 is_a: GO:0060284 {is_inferred="true"} ! regulation of cell development
-is_a: GO:1905207 {is_inferred="true"} ! regulation of cardiocyte differentiation
+is_a: GO:2000725 {is_inferred="true"} ! regulation of cardiac muscle cell differentiation
 
 [Term]
 id: GO:0061051 ! positive regulation of cell growth involved in cardiac muscle cell development
@@ -135005,10 +135013,9 @@
 is_a: GO:0010613 {is_inferred="true"} ! positive regulation of cardiac muscle hypertrophy
 is_a: GO:0010720 {is_inferred="true"} ! positive regulation of cell development
 is_a: GO:0030307 {is_inferred="true"} ! positive regulation of cell growth
-is_a: GO:0051155 {is_inferred="true"} ! positive regulation of striated muscle cell differentiation
 is_a: GO:0055023 {is_inferred="true"} ! positive regulation of cardiac muscle tissue growth
 is_a: GO:0061050 {is_inferred="true"} ! regulation of cell growth involved in cardiac muscle cell development
-is_a: GO:1905209 {is_inferred="true"} ! positive regulation of cardiocyte differentiation
+is_a: GO:2000727 {is_inferred="true"} ! positive regulation of cardiac muscle cell differentiation
 
 [Term]
 id: GO:0061052 ! negative regulation of cell growth involved in cardiac muscle cell development
@@ -135015,10 +135022,9 @@
 is_a: GO:0010614 {is_inferred="true"} ! negative regulation of cardiac muscle hypertrophy
 is_a: GO:0010721 {is_inferred="true"} ! negative regulation of cell development
 is_a: GO:0030308 {is_inferred="true"} ! negative regulation of cell growth
-is_a: GO:0051154 {is_inferred="true"} ! negative regulation of striated muscle cell differentiation
 is_a: GO:0055022 {is_inferred="true"} ! negative regulation of cardiac muscle tissue growth
 is_a: GO:0061050 {is_inferred="true"} ! regulation of cell growth involved in cardiac muscle cell development
-is_a: GO:1905208 {is_inferred="true"} ! negative regulation of cardiocyte differentiation
+is_a: GO:2000726 {is_inferred="true"} ! negative regulation of cardiac muscle cell differentiation
 
 [Term]
 id: GO:0061053 ! somite development
@@ -137979,7 +137985,9 @@
 
 [Term]
 id: GO:0061707 ! extracellular exosome macropinocytosis
+is_a: GO:0051650 {is_inferred="true"} ! establishment of vesicle localization
 is_a: GO:1902538 {is_inferred="true"} ! single-organism macropinocytosis
+is_a: GO:1902580 {is_inferred="true"} ! single-organism cellular localization
 
 [Term]
 id: GO:0061708 ! tRNA-5-taurinomethyluridine 2-sulfurtransferase
@@ -138575,6 +138583,11 @@
 is_a: GO:0048029 {is_inferred="true"} ! monosaccharide binding
 
 [Term]
+id: GO:0070062 ! extracellular exosome
+is_a: GO:0031988 {is_inferred="true"} ! membrane-bounded vesicle
+is_a: GO:1903561 {is_inferred="true"} ! extracellular vesicle
+
+[Term]
 id: GO:0070063 ! RNA polymerase binding
 is_a: GO:0019899 {is_inferred="true"} ! enzyme binding
 
@@ -147128,6 +147141,10 @@
 is_a: GO:0015137 {is_inferred="true"} ! citrate transmembrane transporter activity
 
 [Term]
+id: GO:0071914 ! prominosome
+is_a: GO:1903561 {is_inferred="true"} ! extracellular vesicle
+
+[Term]
 id: GO:0071915 ! protein-lysine lysylation
 is_a: GO:0018205 {is_inferred="true"} ! peptidyl-lysine modification
 
@@ -147366,6 +147383,7 @@
 
 [Term]
 id: GO:0071971 ! extracellular exosome assembly
+is_a: GO:0016050 {is_inferred="true"} ! vesicle organization
 is_a: GO:0070925 {is_inferred="true"} ! organelle assembly
 
 [Term]
@@ -162418,6 +162436,13 @@
 is_a: GO:0097458 {is_inferred="true"} ! neuron part
 
 [Term]
+id: GO:0098953 ! receptor diffusion trapping
+is_a: GO:0031503 {is_inferred="true"} ! protein complex localization
+is_a: GO:0051668 {is_inferred="true"} ! localization within membrane
+is_a: GO:0072657 {is_inferred="true"} ! protein localization to membrane
+is_a: GO:1990778 {is_inferred="true"} ! protein localization to cell periphery
+
+[Term]
 id: GO:0098954 ! presynaptic endosome membrane
 is_a: GO:0010008 {is_inferred="true"} ! endosome membrane
 is_a: GO:0044456 {is_inferred="true"} ! synapse part
@@ -162503,7 +162528,9 @@
 
 [Term]
 id: GO:0098970 ! postsynaptic neurotransmitter receptor diffusion trapping
+is_a: GO:0097120 {is_inferred="true"} ! receptor localization to synapse
 is_a: GO:0099628 {is_inferred="true"} ! neurotransmitter receptor diffusion trapping
+is_a: GO:0099645 {is_inferred="true"} ! neurotransmitter receptor localization to postsynaptic specialization membrane
 
 [Term]
 id: GO:0098971 ! anterograde dendritic transport of neurotransmitter receptor complex
@@ -171515,28 +171542,22 @@
 [Term]
 id: GO:1901295 ! regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
 is_a: GO:0010453 {is_inferred="true"} ! regulation of cell fate commitment
-is_a: GO:0051153 {is_inferred="true"} ! regulation of striated muscle cell differentiation
-is_a: GO:0055024 {is_inferred="true"} ! regulation of cardiac muscle tissue development
 is_a: GO:1905066 {is_inferred="true"} ! regulation of canonical Wnt signaling pathway involved in heart development
-is_a: GO:1905207 {is_inferred="true"} ! regulation of cardiocyte differentiation
+is_a: GO:2000725 {is_inferred="true"} ! regulation of cardiac muscle cell differentiation
 
 [Term]
 id: GO:1901296 ! negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
 is_a: GO:0010454 {is_inferred="true"} ! negative regulation of cell fate commitment
-is_a: GO:0051154 {is_inferred="true"} ! negative regulation of striated muscle cell differentiation
-is_a: GO:0055026 {is_inferred="true"} ! negative regulation of cardiac muscle tissue development
 is_a: GO:1901295 {is_inferred="true"} ! regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
 is_a: GO:1905067 {is_inferred="true"} ! negative regulation of canonical Wnt signaling pathway involved in heart development
-is_a: GO:1905208 {is_inferred="true"} ! negative regulation of cardiocyte differentiation
+is_a: GO:2000726 {is_inferred="true"} ! negative regulation of cardiac muscle cell differentiation
 
 [Term]
 id: GO:1901297 ! positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
 is_a: GO:0010455 {is_inferred="true"} ! positive regulation of cell fate commitment
-is_a: GO:0051155 {is_inferred="true"} ! positive regulation of striated muscle cell differentiation
-is_a: GO:0055025 {is_inferred="true"} ! positive regulation of cardiac muscle tissue development
 is_a: GO:1901295 {is_inferred="true"} ! regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
 is_a: GO:1905068 {is_inferred="true"} ! positive regulation of canonical Wnt signaling pathway involved in heart development
-is_a: GO:1905209 {is_inferred="true"} ! positive regulation of cardiocyte differentiation
+is_a: GO:2000727 {is_inferred="true"} ! positive regulation of cardiac muscle cell differentiation
 
 [Term]
 id: GO:1901298 ! regulation of hydrogen peroxide-mediated programmed cell death
@@ -177186,6 +177207,15 @@
 is_a: GO:0008104 {is_inferred="true"} ! protein localization
 
 [Term]
+id: GO:1902415 ! regulation of mRNA binding
+is_a: GO:1905214 {is_inferred="true"} ! regulation of RNA binding
+
+[Term]
+id: GO:1902416 ! positive regulation of mRNA binding
+is_a: GO:1902415 {is_inferred="true"} ! regulation of mRNA binding
+is_a: GO:1905216 {is_inferred="true"} ! positive regulation of RNA binding
+
+[Term]
 id: GO:1902417 ! (+)-abscisic acid D-glucopyranosyl ester transmembrane transporter activity
 is_a: GO:0042947 {is_inferred="true"} ! glucoside transmembrane transporter activity
 
@@ -179796,6 +179826,20 @@
 is_a: GO:1903862 {is_inferred="true"} ! positive regulation of oxidative phosphorylation
 
 [Term]
+id: GO:1902959 ! regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
+is_a: GO:1905245 {is_inferred="true"} ! regulation of aspartic-type peptidase activity
+
+[Term]
+id: GO:1902960 ! negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
+is_a: GO:1902959 {is_inferred="true"} ! regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
+is_a: GO:1905246 {is_inferred="true"} ! negative regulation of aspartic-type peptidase activity
+
+[Term]
+id: GO:1902961 ! positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
+is_a: GO:1902959 {is_inferred="true"} ! regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
+is_a: GO:1905247 {is_inferred="true"} ! positive regulation of aspartic-type peptidase activity
+
+[Term]
 id: GO:1902962 ! regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
 is_a: GO:1902991 {is_inferred="true"} ! regulation of amyloid precursor protein catabolic process
 is_a: GO:1904683 {is_inferred="true"} ! regulation of metalloendopeptidase activity
@@ -184035,17 +184079,17 @@
 
 [Term]
 id: GO:1903837 ! regulation of mRNA 3'-UTR binding
-is_a: GO:1905214 {is_inferred="true"} ! regulation of RNA binding
+is_a: GO:1902415 {is_inferred="true"} ! regulation of mRNA binding
 
 [Term]
 id: GO:1903838 ! negative regulation of mRNA 3'-UTR binding
 is_a: GO:1903837 {is_inferred="true"} ! regulation of mRNA 3'-UTR binding
-is_a: GO:1905215 {is_inferred="true"} ! negative regulation of RNA binding
+is_a: GO:1904572 {is_inferred="true"} ! negative regulation of mRNA binding
 
 [Term]
 id: GO:1903839 ! positive regulation of mRNA 3'-UTR binding
+is_a: GO:1902416 {is_inferred="true"} ! positive regulation of mRNA binding
 is_a: GO:1903837 {is_inferred="true"} ! regulation of mRNA 3'-UTR binding
-is_a: GO:1905216 {is_inferred="true"} ! positive regulation of RNA binding
 
 [Term]
 id: GO:1903840 ! response to arsenite(3-)
@@ -187692,18 +187736,23 @@
 is_a: GO:1904569 {is_inferred="true"} ! regulation of selenocysteine incorporation
 
 [Term]
+id: GO:1904572 ! negative regulation of mRNA binding
+is_a: GO:1902415 {is_inferred="true"} ! regulation of mRNA binding
+is_a: GO:1905215 {is_inferred="true"} ! negative regulation of RNA binding
+
+[Term]
 id: GO:1904573 ! regulation of selenocysteine insertion sequence binding
-is_a: GO:1905214 {is_inferred="true"} ! regulation of RNA binding
+is_a: GO:1902415 {is_inferred="true"} ! regulation of mRNA binding
 
 [Term]
 id: GO:1904574 ! negative regulation of selenocysteine insertion sequence binding
+is_a: GO:1904572 {is_inferred="true"} ! negative regulation of mRNA binding
 is_a: GO:1904573 {is_inferred="true"} ! regulation of selenocysteine insertion sequence binding
-is_a: GO:1905215 {is_inferred="true"} ! negative regulation of RNA binding
 
 [Term]
 id: GO:1904575 ! positive regulation of selenocysteine insertion sequence binding
+is_a: GO:1902416 {is_inferred="true"} ! positive regulation of mRNA binding
 is_a: GO:1904573 {is_inferred="true"} ! regulation of selenocysteine insertion sequence binding
-is_a: GO:1905216 {is_inferred="true"} ! positive regulation of RNA binding
 
 [Term]
 id: GO:1904576 ! response to tunicamycin
@@ -191099,6 +191148,14 @@
 is_a: GO:0021895 {is_inferred="true"} ! cerebral cortex neuron differentiation
 
 [Term]
+id: GO:1905274 ! regulation of modification of postsynaptic actin cytoskeleton
+is_a: GO:1905244 {is_inferred="true"} ! regulation of modification of synaptic structure
+
+[Term]
+id: GO:1905275 ! Rohon-Beard neuron differentiation
+is_a: GO:0030154 {is_inferred="true"} ! cell differentiation
+
+[Term]
 id: GO:1990000 ! amyloid fibril formation
 is_a: GO:0019538 {is_inferred="true"} ! protein metabolic process
 is_a: GO:0044710 {is_inferred="true"} ! single-organism metabolic process
@@ -193359,6 +193416,8 @@
 [Term]
 id: GO:1990563 ! extracellular exosome complex
 is_a: GO:0043234 {is_inferred="true"} ! protein complex
+is_a: GO:0044421 {is_inferred="true"} ! extracellular region part
+is_a: GO:0044422 {is_inferred="true"} ! organelle part
 
 [Term]
 id: GO:1990564 ! protein polyufmylation
@@ -194191,6 +194250,7 @@
 
 [Term]
 id: GO:1990771 ! clathrin-mediated extracellular exosome endocytosis
+is_a: GO:0051650 {is_inferred="true"} ! establishment of vesicle localization
 is_a: GO:0072583 {is_inferred="true"} ! clathrin-mediated endocytosis
 
 [Term]
@@ -195140,6 +195200,17 @@
 is_a: GO:2000780 {is_inferred="true"} ! negative regulation of double-strand break repair
 
 [Term]
+id: GO:2000043 ! regulation of cardiac cell fate specification
+is_a: GO:0042659 {is_inferred="true"} ! regulation of cell fate specification
+is_a: GO:1905207 {is_inferred="true"} ! regulation of cardiocyte differentiation
+
+[Term]
+id: GO:2000044 ! negative regulation of cardiac cell fate specification
+is_a: GO:0009996 {is_inferred="true"} ! negative regulation of cell fate specification
+is_a: GO:1905208 {is_inferred="true"} ! negative regulation of cardiocyte differentiation
+is_a: GO:2000043 {is_inferred="true"} ! regulation of cardiac cell fate specification
+
+[Term]
 id: GO:2000045 ! regulation of G1/S transition of mitotic cell cycle
 is_a: GO:1901990 {is_inferred="true"} ! regulation of mitotic cell cycle phase transition
 is_a: GO:1902806 {is_inferred="true"} ! regulation of cell cycle G1/S phase transition
@@ -198450,15 +198521,13 @@
 [Term]
 id: GO:2000690 ! regulation of cardiac muscle cell myoblast differentiation
 is_a: GO:0045661 {is_inferred="true"} ! regulation of myoblast differentiation
-is_a: GO:1905207 {is_inferred="true"} ! regulation of cardiocyte differentiation
-is_a: GO:2000736 {is_inferred="true"} ! regulation of stem cell differentiation
+is_a: GO:0051890 {is_inferred="true"} ! regulation of cardioblast differentiation
 
 [Term]
 id: GO:2000691 ! negative regulation of cardiac muscle cell myoblast differentiation
 is_a: GO:0045662 {is_inferred="true"} ! negative regulation of myoblast differentiation
-is_a: GO:1905208 {is_inferred="true"} ! negative regulation of cardiocyte differentiation
+is_a: GO:0051892 {is_inferred="true"} ! negative regulation of cardioblast differentiation
 is_a: GO:2000690 {is_inferred="true"} ! regulation of cardiac muscle cell myoblast differentiation
-is_a: GO:2000737 {is_inferred="true"} ! negative regulation of stem cell differentiation
 
 [Term]
 id: GO:2000692 ! negative regulation of seed maturation
@@ -198500,9 +198569,8 @@
 [Term]
 id: GO:2000700 ! positive regulation of cardiac muscle cell myoblast differentiation
 is_a: GO:0045663 {is_inferred="true"} ! positive regulation of myoblast differentiation
-is_a: GO:1905209 {is_inferred="true"} ! positive regulation of cardiocyte differentiation
+is_a: GO:0051891 {is_inferred="true"} ! positive regulation of cardioblast differentiation
 is_a: GO:2000690 {is_inferred="true"} ! regulation of cardiac muscle cell myoblast differentiation
-is_a: GO:2000738 {is_inferred="true"} ! positive regulation of stem cell differentiation
 
 [Term]
 id: GO:2000701 ! glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
@@ -198608,6 +198676,43 @@
 is_a: GO:0045944 {is_inferred="true"} ! positive regulation of transcription from RNA polymerase II promoter
 
 [Term]
+id: GO:2000722 ! regulation of cardiac vascular smooth muscle cell differentiation
+is_a: GO:1905063 {is_inferred="true"} ! regulation of vascular smooth muscle cell differentiation
+is_a: GO:1905207 {is_inferred="true"} ! regulation of cardiocyte differentiation
+
+[Term]
+id: GO:2000723 ! negative regulation of cardiac vascular smooth muscle cell differentiation
+is_a: GO:1905064 {is_inferred="true"} ! negative regulation of vascular smooth muscle cell differentiation
+is_a: GO:1905208 {is_inferred="true"} ! negative regulation of cardiocyte differentiation
+is_a: GO:2000722 {is_inferred="true"} ! regulation of cardiac vascular smooth muscle cell differentiation
+
+[Term]
+id: GO:2000724 ! positive regulation of cardiac vascular smooth muscle cell differentiation
+is_a: GO:1905065 {is_inferred="true"} ! positive regulation of vascular smooth muscle cell differentiation
+is_a: GO:1905209 {is_inferred="true"} ! positive regulation of cardiocyte differentiation
+is_a: GO:2000722 {is_inferred="true"} ! regulation of cardiac vascular smooth muscle cell differentiation
+
+[Term]
+id: GO:2000725 ! regulation of cardiac muscle cell differentiation
+is_a: GO:0051153 {is_inferred="true"} ! regulation of striated muscle cell differentiation
+is_a: GO:0055024 {is_inferred="true"} ! regulation of cardiac muscle tissue development
+is_a: GO:1905207 {is_inferred="true"} ! regulation of cardiocyte differentiation
+
+[Term]
+id: GO:2000726 ! negative regulation of cardiac muscle cell differentiation
+is_a: GO:0051154 {is_inferred="true"} ! negative regulation of striated muscle cell differentiation
+is_a: GO:0055026 {is_inferred="true"} ! negative regulation of cardiac muscle tissue development
+is_a: GO:1905208 {is_inferred="true"} ! negative regulation of cardiocyte differentiation
+is_a: GO:2000725 {is_inferred="true"} ! regulation of cardiac muscle cell differentiation
+
+[Term]
+id: GO:2000727 ! positive regulation of cardiac muscle cell differentiation
+is_a: GO:0051155 {is_inferred="true"} ! positive regulation of striated muscle cell differentiation
+is_a: GO:0055025 {is_inferred="true"} ! positive regulation of cardiac muscle tissue development
+is_a: GO:1905209 {is_inferred="true"} ! positive regulation of cardiocyte differentiation
+is_a: GO:2000725 {is_inferred="true"} ! regulation of cardiac muscle cell differentiation
+
+[Term]
 id: GO:2000728 ! regulation of mRNA export from nucleus in response to heat stress
 is_a: GO:0010793 {is_inferred="true"} ! regulation of mRNA export from nucleus
 is_a: GO:1900034 {is_inferred="true"} ! regulation of cellular response to heat

changes in entailments

GO Inferences Log