For background see: https://www.ebi.ac.uk/panda/jira/browse/GO-190

== OWL ==

FILE: mf-plus.owl

This is the MF ontology, plus equivalence axioms to RHEA. In addition,
each RHEA class should have equivalence axioms (only done for bidi so
far).

The equivalence axioms are in terms of CHEMICAL BAGS, corresponding to
a set of chemical entities (CHEBI) plus their stoichiometry
(cardinality).

Each reaction has 2 bags.

Problem: use of cardinality, won't scale.



== REPORTING ==

FILE: go-rhea-align-via-xref.rpt

 - GO_ID
 - GO_NAME
 - RHEA_ID
 - RHEA_NAME (currently blank)
 - EC
 - Match Type

This file contains matches between GO and RHEA based on ECs in common.

The final column states whether this inferred match is consistent with
what is the asserted GO RHEA xref

Possible values

 - missing : there is no asserted RHEA for this GO ID
 - is_inconsistent : the GO ID has an entirely different RHEA
 - is_consistent : this assertion is in GO

The last type is further broken down by whether the mapping is 1:1,
M:M., 1:M or M:1

Example of is_inconsistent:

GO:0052662      zeaxanthin epoxidase activity   RHEA:14940              EC:1.14.13.90           is_inconsistent/RHEA:24085
GO DEF: zeaxanthin + NAD(P)H + H+ + O2 = antheraxanthin + NAD(P)+ + H2O


http://www.ebi.ac.uk/rhea/reaction.xhtml?id=14940
    antheraxanthin + H+ + NADPH + O2 <=> all-trans-violaxanthin + H2O + NADP+

http://www.ebi.ac.uk/rhea/reaction.xhtml?id=24085
    antheraxanthin + H2O + NADP+ <= H+ + NADPH + O2 + zeaxanthin 

(Note that the RHEA<->EC is for unidrectional here)

I think here the alternate is better