CYP1ALPHA
CYP27B
CYP27B1
UniProt:O15528 CYP27B1
CYP24
CYP24A1
UniProt:Q07973 CYP24A1
CYP2R1
UniProt:Q6VVX0 CYP2R1
CYP26A2
CYP26B1
P450RAI2
UniProt:Q9NR63 CYP26B1
25-Hydroxylation of vitamin D3 in liver
Further hydroxylation of calcidiol in kidney to form calcitriol
CYP24A1 catalyzes the initial step in the deactivation of the hormonally active form of vitamin D3
CYP26A1 breaks down all-trans-retinoic acid by 4-hydroxylation
CYP26B1 also deactivates all-trans-retinoic acid by 4-hydroxylation
CYP26C1 deactivates 9-cis-retinoic acid by 4-hydroxylation
Vitamins