Homodimerization of VEGF proteins
VEGF-A,B,PLGF bind to VEGFR1 leading to receptor dimerization
VEGF-A,C,D bind to VEGFR2 leading to receptor dimerization
VEGF-C,D bind to VEGFR3 leading to receptor dimerization
NRP-1 forms a ternary complex with VEGF165 and VEGFR1
NRP-2 associates with VEGFR1 forming complexes on cell surface
Signaling by VEGF
Signaling by Vascular Epithelial Growth Factors (VEGF)
VEGF ligand-receptor interactions
VEGF binds to VEGFR leading to receptor dimerization
Neurophilin interactions with VEGF and VEGFR