ERK1
label: MAPK3
label: PRKM3
label: UniProt:P27361 MAPK3

De-phosphorylation of IRS
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004725
BFO_0000050: Signal attenuation

De-phosphorylation of SHC
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004725
BFO_0000050: Signal attenuation

SOS phosphorylation and dissociation (SHC)
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: enabled by
  some values from: ERK1
type: GO_0016301
BFO_0000050: Signal attenuation

SOS phosphorylation and dissociation (IRS)
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: enabled by
  some values from: ERK1
type: GO_0016301
BFO_0000050: Signal attenuation

SOS phosphorylation and dissociation (IRS, Crk)
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: enabled by
  some values from: ERK1
type: GO_0016301
BFO_0000050: Signal attenuation

Binding of Grb10 to the insulin receptor
type: GO_0003674
BFO_0000050: Signal attenuation

Signal attenuation
type: GO_0008150