Transesterification to connect viral DNA 3' ends to host DNA 5' ends
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005654
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005654
type: GO_0008907
BFO_0000050: Integration of viral DNA into host genomic DNA
directly activates: Gap repair completes provirus integration

Gap repair completes provirus integration
type: GO_0003674
BFO_0000050: Integration of viral DNA into host genomic DNA

Formation of Pre-Integration Complex (PIC)
type: GO_0003674
BFO_0000050: Integration of provirus
directly activates: Integrase binds viral DNA ends

Integrase binds viral DNA ends
type: GO_0003674
BFO_0000050: Integration of provirus
directly activates: Terminal (3' end) cleavage of viral DNA

Terminal (3' end) cleavage of viral DNA
type: GO_0003674
BFO_0000050: Integration of provirus
directly activates: Import of PIC to the Host Nucleus
directly activates: Control182
directly activates: Control183

Import of PIC to the Host Nucleus
type: GO_0051169
BFO_0000050: Integration of provirus
directly activates: Target DNA binding
directly activates: 1-LTR circle formation
directly activates: Association of Ku heterodimer with viral DNA ends
directly activates: Suicidal integration leading to inverted circle formation
directly activates: Suicidal integration leading to smaller circles of viral DNA
directly activates: Integration of viral DNA into host genomic DNA
directly activates: 2-LTR circle formation
directly activates: Autointegration results in viral DNA circles

Target DNA binding
type: GO_0003674
BFO_0000050: Integration of viral DNA into host genomic DNA
directly activates: Transesterification to connect viral DNA 3' ends to host DNA 5' ends
directly activates: Catalysis96

1-LTR circle formation
type: GO_0003674
BFO_0000050: Integration of provirus

Association of Ku heterodimer with viral DNA ends
type: GO_0003674
BFO_0000050: 2-LTR circle formation
directly activates: Association of XRCC4:DNA ligase IV complex with viral DNA ends

Association of XRCC4:DNA ligase IV complex with viral DNA ends
type: GO_0003674
BFO_0000050: 2-LTR circle formation
directly activates: 2-LTR formation due to circularization of viral DNA
directly activates: Catalysis1136

2-LTR formation due to circularization of viral DNA
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005654
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005654
type: GO_0003909
BFO_0000050: 2-LTR circle formation

Suicidal integration leading to inverted circle formation
type: GO_0003674
BFO_0000050: Autointegration results in viral DNA circles

Suicidal integration leading to smaller circles of viral DNA
type: GO_0003674
BFO_0000050: Autointegration results in viral DNA circles

Integration of provirus
type: GO_0008150

Integration of viral DNA into host genomic DNA
type: GO_0008150
BFO_0000050: Integration of provirus

2-LTR circle formation
type: GO_0008150
BFO_0000050: Integration of provirus

Autointegration results in viral DNA circles
type: GO_0008150
BFO_0000050: Integration of provirus