Transesterification to connect viral DNA 3' ends to host DNA 5' ends
Gap repair completes provirus integration
Formation of Pre-Integration Complex (PIC)
Integrase binds viral DNA ends
Terminal (3' end) cleavage of viral DNA
Import of PIC to the Host Nucleus
Target DNA binding
1-LTR circle formation
Association of Ku heterodimer with viral DNA ends
Association of XRCC4:DNA ligase IV complex with viral DNA ends
2-LTR formation due to circularization of viral DNA
Suicidal integration leading to inverted circle formation
Suicidal integration leading to smaller circles of viral DNA
Integration of provirus
Integration of viral DNA into host genomic DNA
2-LTR circle formation
Autointegration results in viral DNA circles