Formation of Cyclin D:Cdk4/6 complexes
Translocation of Cyclin D:Cdk4/6 complexes from the cytoplasm to the nucleus
Phosphorylation of Cyclin D:Cdk4/6 complexes
Cyclin D:Cdk4/6 mediated phosphorylation of Rb and dissociation of phospho-Rb from the E2F1/2/3:DP-1 complexes
Association of INK4A with Cdk4/6
Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex
Dephosphorylation of p107 (RBL1) by PP2A
Dephosphorylation of p107 by PP2A
Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex
Dephosphorylation of p130 (RBL2) by PP2A
Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex
Ubiquitination of p130 (RBL2) by SCF (Skp2)
G1 Phase
Cyclin D associated events in G1