MGLL
label: UniProt:Q99685 MGLL

Transport of Ca++ from platelet dense tubular system to cytoplasm
type: Restriction
  on property: BFO_0000066
  some values from: GO_0031095
type: GO_0005262
BFO_0000050: Effects of PIP2 hydrolysis
directly activates: Calcium and Diacylglycerol activate CalDAG-GEFs (RasGRPs)
directly activates: BiochemicalReaction2356
directly activates: BiochemicalReaction242
directly activates: Control159

Binding of IP3 to IP3 receptor
type: GO_0003674
BFO_0000050: Effects of PIP2 hydrolysis
directly activates: Transport of Ca++ from platelet dense tubular system to cytoplasm
directly activates: Catalysis1004

Calcium and Diacylglycerol activate CalDAG-GEFs (RasGRPs)
type: GO_0003674
BFO_0000050: Effects of PIP2 hydrolysis
directly activates: BiochemicalReaction850
directly activates: BiochemicalReaction851
directly activates: Catalysis321
directly activates: Catalysis322

Activation of Protein Kinase C novel isoforms
type: GO_0003674
BFO_0000050: Effects of PIP2 hydrolysis

DAG activation of TRPC channels
type: GO_0003674
BFO_0000050: Effects of PIP2 hydrolysis
directly activates: BiochemicalReaction2250
directly activates: Catalysis1006

DAG is metabolized by DAGL to 2-AG
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0047372
BFO_0000050: Arachidonate production from DAG
directly activates: 2-AG hydrolysis to arachidonate by MAGL
directly activates: Catalysis1037

2-AG hydrolysis to arachidonate by MAGL
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: enabled by
  some values from: MGLL
type: Restriction
  on property: enabled by
  some values from: MGLL
type: GO_0047372
BFO_0000050: Arachidonate production from DAG

DAG kinase produces phosphatidic acid from DAG
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004143
BFO_0000050: Effects of PIP2 hydrolysis

Effects of PIP2 hydrolysis
type: GO_0008150

Arachidonate production from DAG
type: GO_0008150
BFO_0000050: Effects of PIP2 hydrolysis