Gene Ontology OBO file definition changes
Files used:
- file 1 (old): 03:06:2011 15:49, cvs revision 1.2009
- file 2 (new): 10:06:2011 13:58, cvs revision 1.2028
- Database: seqdb, 2011-06-11
Terms with changed definitions
GO:0004568 : chitinase activity
OLD: Catalysis of the random hydrolysis of N-acetyl-beta-D-glucosaminide 1,4-beta-linkages in chitin and chitodextrins.
NEW: Catalysis of the hydrolysis of 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins.
GO:0005042 : netrin receptor activity
OLD: A transmembrane receptor activity that responds to the netrin family of ligands and results in chemotaxis when activated.
NEW: Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
GO:0005043 : netrin receptor activity involved in chemorepulsion
(was repulsive netrin receptor activity)
OLD: A transmembrane receptor activity that responds to the netrin family of ligands and results in chemorepulsion when activated.
NEW: Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell away from a higher concentration of netrin.
GO:0006490 : oligosaccharide-lipid intermediate biosynthetic process
(was oligosaccharide-lipid intermediate metabolic process)
OLD: The cellular metabolic process in which an intermediate molecule of dolichol-P-man or dolicol-P-Glc is assembled to be used in N-linked glycosylation.
NEW: The chemical reactions and pathways resulting in the formation of an oligosaccharide-lipid intermediate, such as a molecule of dolichol-P-man or dolicol-P-Glc used in N-linked glycosylation.
GO:0007174 : epidermal growth factor catabolic process
(was epidermal growth factor ligand processing)
OLD: The proteolysis of epidermal growth factor after its internalization via binding to its receptor.
NEW: The chemical reactions and pathways resulting in the breakdown of epidermal growth factor (EGF), following internalization of the receptor-bound ligand into the signal-receiving cell. Full breakdown of epidermal growth factor results in a ligand that is unable to bind and activate its receptor.
GO:0008843 : endochitinase activity
OLD: Catalysis of the hydrolysis of nonterminal 1,4-beta-linkages of N-acetyl-D-glucosamine polymers of chitin and chitodextrins.
NEW: Catalysis of the hydrolysis of nonterminal 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, endochitinases cleave randomly within the chitin chain.
GO:0018845 : 2-hydroxychromene-2-carboxylate isomerase activity
OLD: Catalysis of the reaction: 2-hydroxychromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate. (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate is also known as trans-o-hydroxybenzylidenepyruvate.
NEW: Catalysis of the reaction: 2-hydroxychromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate. (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate is also known as trans-o-hydroxybenzylidenepyruvate.
GO:0023052 : signaling
OLD: The entirety of a process in which information is transmitted. This process begins with an active signal and ends when a response has been triggered.
NEW: The entirety of a process in which information is transmitted. This process begins with an active signal and ends when a cellular response has been triggered.
GO:0030518 : steroid hormone receptor signaling pathway
OLD: Any series of molecular signals generated as a consequence of a steroid hormone binding to its receptor.
NEW: Any series of molecular signals generated as a consequence of a steroid hormone receptor binding to one of its physiological ligands.
GO:0035638 : signal maturation
OLD: Any process leading to the attainment of the full functional capacity of a signal. A signal is a physical entity or change in state that is used to transfer information to trigger a response.
NEW: Any process leading to the attainment of the full functional capacity of a signal. A signal is a physical entity or change in state that is used to transfer information to trigger a response, and is functional when it can activate a receptor.
GO:0043401 : steroid hormone mediated signaling pathway
OLD: A series of molecular signals mediated by the detection of a steroid hormone.
NEW: A series of molecular signals mediated by a steroid hormone binding to a receptor.
GO:0047807 : cytokinin 7-beta-glucosyltransferase activity
OLD: Catalysis of the reaction: UDP-glucose + N6-alkylaminopurine = UDP + N6-alkylaminopurine-7-beta-D-glucoside.
NEW: Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-7-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event.
GO:0050785 : advanced glycation end-product receptor activity
OLD: Combining with advanced glycation end-products to initiate a change in cell activity.
NEW: Combining with advanced glycation end-products to initiate a change in cell activity. Advanced glycation end-products (AGEs) form from a series of chemical reactions after an initial glycation event (a non-enzymatic reaction between reducing sugars and free amino groups of proteins).
GO:0080062 : cytokinin 9-beta-glucosyltransferase activity
OLD: Catalysis of the reaction: UDP-glucose + N6-alkylaminopurine = UDP + N6-alkylaminopurine-9-beta-D-glucoside.
NEW: Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-9-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event.