Gene Ontology Definition Changes
Files used:
- file 1 (old): 15:12:2011 15:48, cvs revision 1.2455
- file 2 (new): 23:12:2011 10:41, cvs revision 1.2470
- Database: unknown DB type, unknown DB release name
Terms with changed definitions
GO:0001649 : osteoblast differentiation
OLD: The process in which a relatively unspecialized cell acquires the specialized features of an osteoblast, the mesodermal cell that gives rise to bone.
NEW: The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.
GO:0001957 : intramembranous ossification
OLD: The formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified. Intramembranous ossification is the way flat bones and the shell of a turtle are formed.
NEW: Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells.
GO:0001958 : endochondral ossification
OLD: The formation of bone by the replacement of cartilage tissue with mineralized bone.
NEW: Replacement ossification wherein bone tissue replaces cartilage.
GO:0004965 : G-protein coupled GABA receptor activity
(was GABA-B receptor activity)
OLD: Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-B receptors are G-protein coupled receptors.
NEW: Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
GO:0006919 : activation of cysteine-type endopeptidase activity involved in apoptotic process
(was activation of caspase activity)
OLD: Upregulation of the activity of a caspase, any of a group of cysteine proteases involved in apoptosis.
NEW: Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process.
GO:0008635 : activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
(was activation of caspase activity by cytochrome c)
OLD: Upregulation of the activity of a caspase, any of a group of cysteine proteases involved in apoptosis, mediated by cytochrome c.
NEW: Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process and is mediated by cytochrome c.
GO:0030514 : negative regulation of BMP signaling pathway
OLD: Any process that stops, prevents, or reduces the frequency, rate or extent of BMP signaling pathway activity.
NEW: Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
0 annotations
GO:0031795 : G-protein coupled GABA receptor binding
(was metabotropic GABA receptor binding)
OLD: Interacting selectively and non-covalently with a metabotropic GABA receptor.
NEW: Interacting selectively and non-covalently with a G-protein coupled (metabotropic) GABA receptor.
0 annotations
GO:0031806 : G-protein coupled histamine receptor binding
(was metabotropic histamine receptor binding)
OLD: Interacting selectively and non-covalently with a metabotropic histamine receptor.
NEW: Interacting selectively and non-covalently with a G-protein coupled (metabotropic) histamine receptor.
0 annotations
GO:0031811 : G-protein coupled nucleotide receptor binding
(was metabotropic nucleotide receptor binding)
OLD: Interacting selectively and non-covalently with a metabotropic nucleotide receptor.
NEW: Interacting selectively and non-covalently with a G-protein coupled (metabotropic) nucleotide receptor.
GO:0035256 : G-protein coupled glutamate receptor binding
(was metabotropic glutamate receptor binding)
OLD: Interacting selectively and non-covalently with a metabotropic glutamate receptor. Metabotropic glutamate receptors are G-protein coupled receptors that bind glutamate and exert an effect through the regulation of enzyme activity.
NEW: Interacting selectively and non-covalently with a G-protein coupled glutamate receptor (a metabotropic glutamate receptor).
GO:0043932 : ossification involved in bone remodeling
OLD: The formation of bone involved in the continuous turnover of bone matrix and mineral.
NEW: The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli.
0 annotations
GO:0044358 : envenomation resulting in hemorrhagic damage to other organism
OLD: The process begins with venom being forced into an organism by the bite or sting of another organism, and ends with vascular damage and hemorrhage in the bitten organism.
NEW: A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with vascular damage and hemorrhage in the bitten organism.
0 annotations
GO:0044365 : envenomation resulting in modulation of platelet aggregation in other organism
OLD: The process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with changes to the frequency, rate or extent of platelet aggregation in the bitten organism.
NEW: A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with changes to the frequency, rate or extent of platelet aggregation in the bitten organism.
0 annotations
GO:2001282 : negative regulation of muscle cell chemotaxis toward tendon cell
OLD: Any process that stops, prevents or reduces the frequency, rate or extent of muscle cell chemotaxis toward tendon cell.
NEW: Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a muscle cell towards a tendon cell in response to an external stimulus. For example, when the muscle cell arrives at the target tendon cell, migration is arrested so that attachments can be made between the cells.
0 annotations
GO:2001283 : Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cell
OLD: Any Roundabout signaling pathway that is involved in muscle cell chemotaxis toward tendon cell.
NEW: Any Roundabout signaling pathway that is involved in the directed movement of a muscle cell towards a tendon cell in response to an external stimulus.