Gene Ontology: Ontology Comparison Report
Files used:
- file 1 (old): go-2011-11-19.obo; date: 18:11:2011 17:55; CVS revision: 1.2388
- file 2 (new): go-2011-11-26.obo; date: 24:11:2011 22:03; CVS revision: 1.2403
New terms
Obsoletions
None
Term merges
Old ID | Old name | Merged into | Merged term name |
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GO:0034619 | cellular chaperone-mediated protein complex assembly | GO:0051131 | chaperone-mediated protein complex assembly |
Term changes
File 1 (18:11:2011 17:55, 1.2388) | File 2 (24:11:2011 22:03, 1.2403) |
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GO:0006351 : transcription, DNA-dependent | |
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subset goslim_pombe |
GO:0006366 : transcription from RNA polymerase II promoter | |
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subset |
GO:0006636 : unsaturated fatty acid biosynthetic process | |
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synonym "polyunsaturated fatty acid biosynthesis" NARROW [GOC:yaf, MetaCyc:PWY-762] |
GO:0006915 : apoptotic process | |
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name def |
name apoptotic process def A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathways) which typically lead to rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. The process ends when the cell has died. The process is divided into a signaling pathway phase and into an execution phase, which is triggered by the former. synonym "apoptosis" NARROW [] "cell suicide" BROAD [] "cellular suicide" BROAD [] |
GO:0007165 : signal transduction | |
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def |
def The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
GO:0007166 : cell surface receptor linked signaling pathway | |
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def |
def A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription. |
GO:0007186 : G-protein coupled receptor signaling pathway | |
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def |
def Any series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. |
GO:0007194 : negative regulation of adenylate cyclase activity | |
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is_a GO:0030818 |
GO:0007532 : regulation of mating-type specific transcription, DNA-dependent | |
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name def |
name regulation of mating-type specific transcription, DNA-dependent def Any mating-type specific process that modulates the frequency, rate or extent of cellular DNA-dependent transcription. |
GO:0008219 : cell death | |
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def |
def Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as \"apoptotic bodies\"); and/or (3) its corpse (or its fragments) have been engulfed by an adjacent cell in vivo. |
GO:0012501 : programmed cell death | |
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def |
def A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell. synonym "PCD" EXACT [] |
GO:0012507 : ER to Golgi transport vesicle membrane | |
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synonym "ER to Golgi constitutive secretory pathway transport vesicle membrane" EXACT [] |
GO:0012508 : Golgi to ER transport vesicle membrane | |
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synonym "Golgi to ER constitutive secretory pathway transport vesicle membrane" EXACT [] |
GO:0012509 : inter-Golgi transport vesicle membrane | |
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synonym "inter-Golgi transport constitutive secretory pathway transport vesicle membrane" EXACT [] |
GO:0012510 : trans-Golgi network transport vesicle membrane | |
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synonym "trans-Golgi network constitutive secretory pathway transport vesicle membrane" EXACT [] |
GO:0015114 : phosphate ion transmembrane transporter activity | |
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synonym "phosphate transmembrane transporter activity" EXACT [GOC:vw] |
GO:0030133 : transport vesicle | |
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synonym "constitutive secretory pathway transport vesicle" EXACT [] |
GO:0030134 : ER to Golgi transport vesicle | |
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synonym "ER to Golgi constitutive secretory pathway transport vesicle" EXACT [] |
GO:0030140 : trans-Golgi network transport vesicle | |
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synonym "trans-Golgi network constitutive secretory pathway transport vesicle" EXACT [] |
GO:0030141 : secretory granule | |
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name |
name secretory granule |
GO:0030142 : Golgi to ER transport vesicle | |
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synonym "Golgi to ER constitutive secretory pathway transport vesicle" EXACT [] |
GO:0030143 : inter-Golgi transport vesicle | |
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synonym "inter-Golgi transport constitutive secretory pathway transport vesicle" EXACT [] |
GO:0030175 : filopodium | |
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synonym |
GO:0030658 : transport vesicle membrane | |
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synonym "constitutive secretory pathway transport vesicle membrane" EXACT [] |
GO:0031234 : extrinsic to internal side of plasma membrane | |
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comment Consider also annotating to 'cell cortex ; GO:0005938'. |
GO:0031931 : TORC1 complex | |
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def |
def A protein complex that contains at least TOR (target of rapamycin) and Raptor (regulatory-associated protein of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of S6K. In Saccharomyces, the complex contains Kog1p, Lst8p, Tco89p, and either Tor1p or Tor2p. synonym "dTOR/dRaptor complex" NARROW [PMID:17183368] "dTORC1" NARROW [PMID:17183368] "mTORC1" NARROW [PMID:18765678, PMID:21548787] "rapamycin and nutrient-sensitive TOR complex" EXACT [PMID:21548787] "TORC1" EXACT [PMID:21548787] |
GO:0031932 : TORC2 complex | |
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def |
def A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p. synonym "mTORC2" NARROW [PMID:20496258, PMID:21548787] "rapamycin and nutrient-insensitive TOR complex" EXACT [PMID:21548787] "TORC2" EXACT [PMID:21548787] |
GO:0034505 : tooth mineralization | |
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def |
def The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum. |
GO:0035727 : lysophosphatidic acid binding | |
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is_a |
is_a GO:0036041 |
GO:0038023 : signaling receptor activity | |
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def comment |
def Receiving a signal and transmitting the signal in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. comment Note that this term and its child terms are intended for receptors that are directly coupled to a signal transduction pathway. This term should therefore not be used to annotate decoy receptors and other proteins that bind a signal but do not pass the signal on. This term can be used to annotate dependence receptors that transduce a signal when a ligand is withdrawn (in this case, signal withdrawal is considered to be the initiating signal), or receptors that signal at a basal level in the absence of a bound agonist. For receptors that mediate transport of a substance into the cell by receptor-mediated endocytosis, consider instead the term 'cargo receptor activity ; GO:0038024' and its children. |
GO:0038035 : G-protein coupled receptor signaling in absence of ligand | |
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is_a GO:0007186 |
GO:0042475 : odontogenesis of dentin-containing tooth | |
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name def synonym |
name odontogenesis of dentin-containing tooth def The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel. comment Note that placoid scales found in the cartilaginous fishes presumably develop through the same processes, but are found on the dermis, rather than in the mouth or pharynx. See http://en.wikipedia.org/wiki/Placoid_scale#Placoid_scales. synonym "odontogenesis of dentine-containing tooth" EXACT [GOC:mah] |
GO:0042487 : regulation of odontogenesis of dentin-containing tooth | |
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name synonym |
name regulation of odontogenesis of dentin-containing tooth synonym "regulation of odontogenesis of dentine-containing tooth" EXACT [GOC:mah] |
GO:0042488 : positive regulation of odontogenesis of dentin-containing tooth | |
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name synonym |
name positive regulation of odontogenesis of dentin-containing tooth synonym "positive regulation of odontogenesis of dentine-containing tooth" RELATED [] |
GO:0042489 : negative regulation of odontogenesis of dentin-containing tooth | |
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name synonym |
name negative regulation of odontogenesis of dentin-containing tooth synonym "negative regulation of odontogenesis of dentine-containing tooth" RELATED [] |
GO:0042981 : regulation of apoptotic process | |
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name def |
name regulation of apoptotic process def Any process that modulates the occurrence or rate of cell death by apoptotic process. comment This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used. synonym "regulation of apoptosis" NARROW [] |
GO:0043065 : positive regulation of apoptotic process | |
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name def |
name positive regulation of apoptotic process def Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process. comment This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is positively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used. synonym "positive regulation of apoptosis" NARROW [] |
GO:0043066 : negative regulation of apoptotic process | |
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name def |
name negative regulation of apoptotic process def Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. comment This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is negatively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used. synonym "negative regulation of apoptosis" NARROW [] |
GO:0045762 : positive regulation of adenylate cyclase activity | |
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is_a GO:0030819 |
GO:0045894 : negative regulation of mating-type specific transcription, DNA-dependent | |
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name def |
name negative regulation of mating-type specific transcription, DNA-dependent def Any mating-type specific process that stops, prevents or reduces the rate of cellular DNA-dependent transcription. |
GO:0045895 : positive regulation of mating-type specific transcription, DNA-dependent | |
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name def |
name positive regulation of mating-type specific transcription, DNA-dependent def Any mating-type specific process that activates or increases the rate of cellular DNA-dependent transcription. |
GO:0046848 : hydroxyapatite binding | |
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def |
def Interacting selectively and non-covalently with hydroxyapatite, the calcium phosphate mineral of formula Ca10(PO4)6(OH)2 found both in rocks of nonorganic origin and as a component of bone and dentin. |
GO:0051131 : chaperone-mediated protein complex assembly | |
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alt_id GO:0034619 synonym "cellular chaperone-mediated protein complex assembly" EXACT [] |
GO:0060199 : clathrin sculpted glutamate transport vesicle | |
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synonym "clathrin sculpted glutamate constitutive secretory pathway transport vesicle" EXACT [] |
GO:0060200 : clathrin sculpted acetylcholine transport vesicle | |
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synonym "clathrin sculpted acetylcholine constitutive secretory pathway transport vesicle" EXACT [] |
GO:0060201 : clathrin sculpted acetylcholine transport vesicle membrane | |
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synonym "clathrin sculpted acetylcholine constitutive secretory pathway transport vesicle membrane" EXACT [] |
GO:0060202 : clathrin sculpted acetylcholine transport vesicle lumen | |
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synonym "clathrin sculpted acetylcholine constitutive secretory pathway transport vesicle lumen" EXACT [] |
GO:0060203 : clathrin sculpted glutamate transport vesicle membrane | |
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synonym "clathrin sculpted glutamate constitutive secretory pathway transport vesicle membrane" EXACT [] |
GO:0060204 : clathrin sculpted glutamate transport vesicle lumen | |
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synonym "clathrin sculpted glutamate constitutive secretory pathway transport vesicle lumen" EXACT [] |
GO:0060640 : positive regulation of dentin-containing tooth bud formation by mesenchymal-epithelial signaling | |
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name |
name positive regulation of dentin-containing tooth bud formation by mesenchymal-epithelial signaling synonym "positive regulation of dentine-containing tooth bud formation by mesenchymal-epithelial signaling" RELATED [] |
GO:0060790 : tooth placode formation | |
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def |
def The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud. |
GO:0061364 : apoptotic process involved in luteolysis | |
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name def |
name apoptotic process involved in luteolysis def The apoptotic process that contributes to luteolysis. synonym "apoptosis involved in luteolysis" NARROW [] intersection_of GO:0006915 part_of GO:0001554 |
GO:0070081 : clathrin sculpted monoamine transport vesicle | |
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synonym "clathrin sculpted monoamine constitutive secretory pathway transport vesicle" EXACT [] |
GO:0070082 : clathrin sculpted monoamine transport vesicle lumen | |
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synonym "clathrin sculpted monoamine constitutive secretory pathway transport vesicle lumen" EXACT [] |
GO:0070083 : clathrin sculpted monoamine transport vesicle membrane | |
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synonym "clathrin sculpted monoamine constitutive secretory pathway transport vesicle membrane" EXACT [] |
GO:0070166 : enamel mineralization | |
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relationship part_of GO:0097186 |
GO:0070319 : Golgi to plasma membrane transport vesicle | |
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synonym "Golgi to plasma membrane constitutive secretory pathway transport vesicle" EXACT [] |
GO:0070381 : endosome to plasma membrane transport vesicle | |
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synonym "endosome to plasma membrane constitutive secretory pathway transport vesicle" EXACT [] |
GO:0070382 : exocytic vesicle | |
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synonym "exocytic constitutive secretory pathway transport vesicle" EXACT [] |
GO:0070468 : dentin secretion | |
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name def synonym |
name dentin secretion def The regulated release by odontoblasts of the extracellular matrix constituents, including collagen, that form the basis of dentin. synonym "dentine secretion" EXACT [GOC:mah] |
GO:0070538 : oleic acid binding | |
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is_a |
is_a GO:0036041 |
GO:0070539 : linoleic acid binding | |
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is_a |
is_a GO:0036041 |
GO:0070540 : stearic acid binding | |
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is_a |
is_a GO:0036041 |
GO:0071895 : odontoblast differentiation | |
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def |
def The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin. |
GO:0090034 : regulation of chaperone-mediated protein complex assembly | |
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name def intersection_of relationship |
name regulation of chaperone-mediated protein complex assembly def Any process that modulates the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex. intersection_of regulates GO:0051131 relationship regulates GO:0051131 |
GO:0090035 : positive regulation of chaperone-mediated protein complex assembly | |
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name def intersection_of relationship |
name positive regulation of chaperone-mediated protein complex assembly def Any process that increases the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex. intersection_of positively_regulates GO:0051131 relationship positively_regulates GO:0051131 |
GO:2001227 : quercitrin binding | |
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File Stats
Ontology | Old file | New file | Change |
---|---|---|---|
molecular function |
9140 9140 (100.0%) defined |
9148 9148 (100.0%) defined |
+8 |
cellular component |
2922 2922 (100.0%) defined |
2924 2924 (100.0%) defined |
+2 |
biological process |
21591 21591 (100.0%) defined |
21603 21603 (100.0%) defined |
+12 |
Obsolete | 1603 (4.5% of total) |
1603 (4.5% of total) |
0 (0.0%) |
Totals |
33653 33653 (100.0%) defined 35256 inc. obsoletes |
33675 33675 (100.0%) defined 35278 inc. obsoletes |
+22 (+0.1%) |