Gene Ontology: Ontology Comparison Report

Files used:

  • file 1 (old): go-2011-11-12.obo; date: 08:11:2011 17:10; CVS revision: 1.2378
  • file 2 (new): go-2011-11-19.obo; date: 18:11:2011 17:55; CVS revision: 1.2388

New terms

ID name namespace
GO:0038046 enkephalin receptor activity molecular_function
GO:0038047 morphine receptor activity molecular_function
GO:0038048 dynorphin receptor activity molecular_function
GO:0072693 protein targeting to prospore membrane biological_process
GO:0097184 response to azide biological_process
GO:0097185 cellular response to azide biological_process
GO:2001227 quercitrin binding molecular_function

Obsoletions

ID name namespace
GO:0001619 lysosphingolipid and lysophosphatidic acid receptor activity
Consider: GO:0038036, GO:0070915
molecular_function
GO:0004986 delta-opioid receptor activity
Consider: GO:0038046
This term was made obsolete because the receptor is defined based on its pharmacological properties.
molecular_function
GO:0004987 kappa-opioid receptor activity
Consider: GO:0038048
This term was made obsolete because the receptor is defined based on its pharmacological properties.
molecular_function
GO:0004988 mu-opioid receptor activity
Consider: GO:0004979, GO:0038046, GO:0038047
This term was made obsolete because the receptor is defined based on its pharmacological properties.
molecular_function
GO:0015051 X-opioid receptor activity
Consider: GO:0001626
This term was made obsolete because the receptor is defined based on its pharmacological properties.
molecular_function
GO:0045233 natural killer cell receptor activity
Consider: GO:0002769, GO:0004888, GO:0030101
This term was made obsolete because the receptor is defined based on its cellular expression pattern, and the definition is inaccurate: receptors on natural killer cells can either activate or inhibit natural killer (NK) cell-mediated cytotoxicity.
molecular_function

Term merges

None

Term changes

Changes in term-related data
File 1 (08:11:2011 17:10, 1.2378) File 2 (18:11:2011 17:55, 1.2388)
GO:0000755 : cytogamy
synonym
"zygote formation" NARROW []
synonym
"zygote formation" RELATED []
GO:0000916 : contractile ring contraction involved in cell cycle cytokinesis
synonym
"contractile ring constriction" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb]
"cytokinesis, contractile ring contraction" EXACT [GOC:dph, GOC:tb]
synonym
"contractile ring constriction" BROAD [GOC:ascb_2009, GOC:dph, GOC:tb]
"cytokinesis, contractile ring contraction" BROAD [GOC:dph, GOC:tb]
GO:0001071 : nucleic acid binding transcription factor activity
relationship
part_of GO:2001141
GO:0001586 : Gi/o-coupled serotonin receptor activity
name
5-HT1 receptor activity
def
A serotonin receptor activity that acts via coupling to Gi/Go to initiate a change in cell activity.
name
Gi/o-coupled serotonin receptor activity
def
Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrease in cyclic AMP (cAMP) levels.
synonym
"5-HT1 receptor activity" EXACT [GOC:bf]
"serotonin receptor activity, coupled via Gi/o" EXACT [GOC:bf]
GO:0001587 : Gq/11-coupled serotonin receptor activity
name
5-HT2 receptor activity
def
A serotonin receptor activity that acts via coupling to G11/q to initiate a change in cell activity.
name
Gq/11-coupled serotonin receptor activity
def
Combining with serotonin and transmitting the signal across the membrane by activation of the Gq/11 subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gq/11 subunit subsequently activates phospholipase C and results in an increase in inositol triphosphate (IP3) levels.
synonym
"5-HT2 receptor activity" BROAD [GOC:bf]
"serotonin receptor activity, coupled via Gq/11" EXACT [GOC:bf]
GO:0001619 : lysosphingolipid and lysophosphatidic acid receptor activity
is_a
GO:0045125
is_obsolete
true
consider
GO:0038036
GO:0070915
GO:0001626 : nociceptin receptor activity
name
nociceptin/orphanin-FQ receptor activity
def
Combining with the peptide nociceptin/orphanin-FQ to initiate a change in cell activity.
is_a
GO:0004930
name
nociceptin receptor activity
def
Combining with the peptide nociceptin, and transmitting the signal across the membrane by activating an associated G-protein.
synonym
"nociceptin/orphanin-FQ receptor activity" EXACT [GOC:bf]
"OFQ receptor activity" EXACT [PR:000012940]
"orphanin-FQ receptor activity" EXACT [GOC:bf]
"X-opioid receptor activity" RELATED [GOC:bf]
is_a
GO:0004985
GO:0004953 : icosanoid receptor activity
relationship
has_part GO:0050542
GO:0004969 : histamine receptor activity
relationship
has_part GO:0051381
GO:0004979 : beta-endorphin receptor activity
def
Combining with beta-endorphin to initiate a change in cell activity.
def
Combining with beta-endorphin, and transmitting the signal across the membrane by activating an associated G-protein. Beta-endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor proopiomelanocortin (POMC).
synonym
"mu-opioid receptor activity" RELATED [GOC:bf]
is_a
GO:0004985
relationship
has_part GO:0031626
GO:0004985 : opioid receptor activity
def
Combining with an opioid, any narcotic derived from or resembling opium, to initiate a change in cell activity.
def
Combining with an opioid (any narcotic derived from or resembling opium), and transmitting the signal across the membrane by activating an associated G-protein.
GO:0004986 : delta-opioid receptor activity
def
Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of delta-opioid receptors, including the activity of enkephalins as ligands.
is_a
GO:0004985
def
OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of delta-opioid receptors, including the activity of enkephalins as ligands.
comment
This term was made obsolete because the receptor is defined based on its pharmacological properties.
is_obsolete
true
consider
GO:0038046
GO:0004987 : kappa-opioid receptor activity
def
Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of kappa-opioid receptors, including high affinity for dynorphins.
is_a
GO:0004985
def
OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of kappa-opioid receptors, including high affinity for dynorphins.
comment
This term was made obsolete because the receptor is defined based on its pharmacological properties.
is_obsolete
true
consider
GO:0038048
GO:0004988 : mu-opioid receptor activity
def
Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of mu-opioid receptors, including high affinity for enkephalins and beta-endorphin but low affinity for dynorphins.
is_a
GO:0004985
def
OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of mu-opioid receptors, including high affinity for enkephalins and beta-endorphin but low affinity for dynorphins.
comment
This term was made obsolete because the receptor is defined based on its pharmacological properties.
is_obsolete
true
consider
GO:0004979
GO:0038046
GO:0038047
GO:0004993 : serotonin receptor activity
def
Combining with the biogenic amine serotonin, a neurotransmitter and hormone found in vertebrates, invertebrates and plants, to initiate a change in cell activity.
def
Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.
relationship
has_part GO:0051378
GO:0004995 : tachykinin receptor activity
def
Combining with tachykinin to initiate a change in cell activity.
def
Combining with a tachykinin neuropeptide and transmitting the signal across the membrane by activating an associated G-protein.
GO:0005055 : laminin receptor activity
relationship
has_part GO:0043236
GO:0005220 : inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
relationship
has_part GO:0070679
GO:0006351 : transcription, DNA-dependent
synonym
"transcription regulator activity" RELATED []
GO:0006352 : transcription initiation, DNA-dependent
synonym
"transcription initiation factor activity" RELATED []
GO:0006353 : transcription termination, DNA-dependent
synonym
"transcription termination factor activity" RELATED []
GO:0006360 : transcription from RNA polymerase I promoter
synonym
"RNA polymerase I transcription factor activity" RELATED []
GO:0006362 : transcription elongation from RNA polymerase I promoter
synonym
"RNA polymerase I transcription elongation factor activity" RELATED []
GO:0006363 : termination of RNA polymerase I transcription
synonym
"RNA polymerase I transcription termination factor activity" RELATED []
GO:0006366 : transcription from RNA polymerase II promoter
synonym
"RNA polymerase II transcription factor activity" RELATED []
GO:0006368 : transcription elongation from RNA polymerase II promoter
synonym
"RNA polymerase II transcription elongation factor activity" RELATED []
GO:0006369 : termination of RNA polymerase II transcription
synonym
"RNA polymerase II transcription termination factor activity" RELATED []
GO:0006383 : transcription from RNA polymerase III promoter
synonym
"RNA polymerase III transcription factor activity" RELATED []
GO:0006385 : transcription elongation from RNA polymerase III promoter
synonym
"RNA polymerase III transcription elongation factor activity" RELATED []
GO:0006386 : termination of RNA polymerase III transcription
synonym
"RNA polymerase III transcription termination factor activity" RELATED []
GO:0007338 : single fertilization
synonym
"zygote biosynthesis" BROAD []
"zygote formation" BROAD []
synonym
"zygote biosynthesis" RELATED []
"zygote formation" RELATED []
GO:0008158 : hedgehog receptor activity
def
Combining with a hedgehog protein to initiate a change in cell activity.
def
Combining with a member of the hedgehog protein family and transmitting the signal across the membrane to initiate a change in cell activity.
GO:0015051 : X-opioid receptor activity
def
Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of X-opioid receptors.
is_a
GO:0004985
def
OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of X-opioid receptors.
comment
This term was made obsolete because the receptor is defined based on its pharmacological properties.
is_obsolete
true
consider
GO:0001626
GO:0016708 : oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor
def
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen is incorporated into one donor.
def
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen are incorporated into one donor.
GO:0021724 : inferior raphe nucleus development
synonym
"inferior central nucleus development" BROAD []
"posterior raphe nucleus development" BROAD []
GO:0021725 : superior raphe nucleus development
synonym
"anterior raphe nucleus development" BROAD []
"superior central nucleus development" BROAD []
GO:0031554 : regulation of transcription termination, DNA-dependent
synonym
"transcription antiterminator activity" RELATED []
GO:0032784 : regulation of transcription elongation, DNA-dependent
synonym
"transcription elongation regulator activity" RELATED []
GO:0032785 : negative regulation of transcription elongation, DNA-dependent
synonym
"negative transcription elongation regulator activity" RELATED []
GO:0032786 : positive regulation of transcription elongation, DNA-dependent
synonym
"positive transcription elongation regulator activity" RELATED []
GO:0045233 : natural killer cell receptor activity
def
A receptor found on the surface of natural killer cells which binds Class I MHC antigens and is required for activation of NK activity. It belongs to the Ly49i family.
is_a
GO:0004888
def
OBSOLETE. A receptor found on the surface of natural killer cells which binds Class I MHC antigens and is required for activation of NK activity. It belongs to the Ly49i family.
comment
This term was made obsolete because the receptor is defined based on its cellular expression pattern, and the definition is inaccurate: receptors on natural killer cells can either activate or inhibit natural killer (NK) cell-mediated cytotoxicity.
is_obsolete
true
consider
GO:0002769
GO:0004888
GO:0030101
GO:0045892 : negative regulation of transcription, DNA-dependent
synonym
"transcription repressor activity" RELATED []
GO:0045893 : positive regulation of transcription, DNA-dependent
synonym
"transcription activator activity" RELATED []
GO:0055119 : relaxation of cardiac muscle
is_a
GO:0055118
GO:0071555 : cell wall organization
is_a
GO:0016043
GO:0072661 : protein targeting to plasma membrane
is_a
GO:0006605
is_a
GO:0006612

File Stats

Term counts for the old and new files
Ontology Old file New file Change
molecular function 9142
9142 (100.0%) defined
9140
9140 (100.0%) defined
-2
cellular component 2922
2922 (100.0%) defined
2922
2922 (100.0%) defined
0
biological process 21588
21588 (100.0%) defined
21591
21591 (100.0%) defined
+3
Obsolete 1597
(4.5% of total)
1603
(4.5% of total)
+6 (+0.4%)
Totals 33652
33652 (100.0%) defined
35249 inc. obsoletes
33653
33653 (100.0%) defined
35256 inc. obsoletes
+7 (0.0%)

Ontology report info