Gene Ontology Ontology Comparison Report ========================== Files used: - file 1 (old): go-2011-10-22.obo; date: 21:10:2011 10:06; CVS revision: 1.2341 - file 2 (new): go-2011-10-29.obo; date: 28:10:2011 16:35; CVS revision: 1.2362 NEW TERMS ========= ID name namespace GO:0036031 recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex biological_process GO:0038034 signal transduction in absence of ligand biological_process GO:0038035 G-protein coupled receptor signaling in absence of ligand biological_process GO:0038036 sphingosine-1-phosphate receptor activity molecular_function GO:0044358 envenomation resulting in hemorrhagic damage to other organism biological_process GO:0044359 modulation of molecular function in other organism biological_process GO:0044360 modulation of voltage-gated potassium channel activity in other organism biological_process GO:0044361 negative regulation of voltage-gated potassium channel activity in other organism biological_process GO:0044362 negative regulation of molecular function in other organism biological_process GO:0044363 modulation of potassium channel activity in other organism biological_process GO:0044364 disruption of cells of other organism biological_process GO:0044365 envenomation resulting in modulation of platelet aggregation in other organism biological_process GO:0044366 feeding on or from other organism biological_process GO:0044367 feeding from tissue of other organism biological_process GO:0044368 feeding from vascular tissue of another organism biological_process GO:0044369 feeding on blood of other organism biological_process GO:0044370 injection of substance into other organism during feeding on blood of other organism biological_process GO:0044371 feeding from phloem of other organism biological_process GO:0044372 feeding from xylem of other organism biological_process GO:0052810 1-phosphatidylinositol-5-kinase activity molecular_function GO:0052811 1-phosphatidylinositol-3-phosphate 4-kinase activity molecular_function GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity molecular_function GO:0052813 phosphatidylinositol bisphosphate kinase activity molecular_function GO:0052814 medium-chain-aldehyde dehydrogenase activity molecular_function GO:0052815 medium-chain acyl-CoA hydrolase activity molecular_function GO:0052816 long-chain acyl-CoA hydrolase activity molecular_function GO:0052817 very long chain acyl-CoA hydrolase activity molecular_function GO:0052818 heteroglycan 3-alpha-mannosyltransferase activity molecular_function GO:0052819 heteroglycan 2-alpha-mannosyltransferase activity molecular_function GO:0052820 DNA-1,N6-ethenoadenine N-glycosylase activity molecular_function GO:0052821 DNA-7-methyladenine glycosylase activity molecular_function GO:0052822 DNA-3-methylguanine glycosylase activity molecular_function GO:0052823 2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity molecular_function GO:0052824 dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity molecular_function GO:0090418 positive regulation of transcription involved in S-phase of mitotic cell cycle biological_process GO:0090419 negative regulation of transcription involved in G2/M-phase of mitotic cell cycle biological_process GO:2001148 regulation of dipeptide transmembrane transport biological_process GO:2001149 negative regulation of dipeptide transmembrane transport biological_process GO:2001150 positive regulation of dipeptide transmembrane transport biological_process GO:2001151 regulation of renal water transport biological_process GO:2001152 negative regulation of renal water transport biological_process GO:2001153 positive regulation of renal water transport biological_process GO:2001154 regulation of glucose catabolic process to ethanol biological_process GO:2001155 negative regulation of glucose catabolic process to ethanol biological_process GO:2001156 regulation of proline catabolic process to glutamate biological_process GO:2001157 negative regulation of proline catabolic process to glutamate biological_process GO:2001158 positive regulation of proline catabolic process to glutamate biological_process GO:2001159 regulation of CVT pathway biological_process GO:2001160 regulation of histone H3-K79 methylation biological_process GO:2001161 negative regulation of histone H3-K79 methylation biological_process GO:2001162 positive regulation of histone H3-K79 methylation biological_process GO:2001163 regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues biological_process GO:2001164 negative regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues biological_process GO:2001165 positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues biological_process GO:2001166 regulation of histone H2B ubiquitination biological_process GO:2001167 negative regulation of histone H2B ubiquitination biological_process GO:2001168 positive regulation of histone H2B ubiquitination biological_process GO:2001169 regulation of ATP biosynthetic process biological_process GO:2001170 negative regulation of ATP biosynthetic process biological_process GO:2001171 positive regulation of ATP biosynthetic process biological_process GO:2001172 positive regulation of glucose catabolic process to ethanol biological_process OBSOLETIONS =========== GO:0000826, inositol pyrophosphate synthase activity (molecular_function) This term was made obsolete because it is incorrectly defined; 'inositol pyrophosphate' is a inositol derivative to which one (or more) pyrophosphate moieties are attached. 'Inositol pyrophosphate synthase' refers to a class of enzymes that catalyze various different reactions that result in the formation of an IP, so one cannot formulate a general reaction for them. Consider: GO:0052746 GO:0004428, inositol or phosphatidylinositol kinase activity (molecular_function) This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids. Consider: GO:0016307, GO:0019140, GO:0052742, GO:0052813 GO:0004437, inositol or phosphatidylinositol phosphatase activity (molecular_function) This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids. Consider: GO:0034593, GO:0034594, GO:0052744, GO:0052745 GO:0017120, polyphosphatidylinositol phosphatase activity (molecular_function) This term was made obsolete because it represents a gene product. Consider: GO:0004438, GO:0034593, GO:0043812 GO:0046853, inositol or phosphatidylinositol phosphorylation (biological_process) This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids. Consider: GO:0046854, GO:0052746 TERM MERGES =========== GO:0016291, acyl-CoA thioesterase activity was merged into GO:0047617, acyl-CoA hydrolase activity GO:0019282, L-methionine biosynthetic process, direct, from O-acetyl-L-homoserine was merged into GO:0003961, O-acetylhomoserine aminocarboxypropyltransferase activity GO:0043868, N-acetylaminoadipate kinase activity was merged into GO:0043744, N2-acetyl-L-aminoadipate kinase activity TERM CHANGES ============ GO:0000009 : alpha-1,6-mannosyltransferase activity - def: Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,6-linkage. + def: Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->6) linkage. + synonym: "1,6-alpha-mannosyltransferase activity" EXACT [] GO:0000016 : lactase activity + xref: Reactome:REACT_114967 "lactose + H2O => D-glucose + D-galactose, Drosophila melanogaster" + xref: Reactome:REACT_112431 "lactose + H2O => D-glucose + D-galactose, Caenorhabditis elegans" GO:0000026 : alpha-1,2-mannosyltransferase activity - def: Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,2-linkage. + def: Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->2) linkage. GO:0000033 : alpha-1,3-mannosyltransferase activity - def: Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,3-linkage. + def: Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->3) linkage. GO:0000048 : peptidyltransferase activity - xref: Reactome:REACT_88081 "Peptide transfer from P-site tRNA to the A-site tRNA, Saccharomyces cerevisiae" + xref: Reactome:REACT_112237 "Peptide transfer from P-site tRNA to the A-site tRNA, Bos taurus" + xref: Reactome:REACT_102632 "Peptide transfer from P-site tRNA to the A-site tRNA, Saccharomyces cerevisiae" + xref: Reactome:REACT_115501 "Peptide transfer from P-site tRNA to the A-site tRNA, Rattus norvegicus" + xref: Reactome:REACT_112282 "Peptide transfer from P-site tRNA to the A-site tRNA, Gallus gallus" GO:0000050 : urea cycle - xref: Reactome:REACT_105230 "Urea cycle, Sus scrofa" + xref: Reactome:REACT_90565 "Urea cycle, Sus scrofa" GO:0000064 : L-ornithine transmembrane transporter activity - xref: Reactome:REACT_89637 "ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic), Bos taurus" GO:0000075 : cell cycle checkpoint - xref: Reactome:REACT_105449 "Cell Cycle Checkpoints, Sus scrofa" - xref: Reactome:REACT_108200 "Cell Cycle Checkpoints, Dictyostelium discoideum" + xref: Reactome:REACT_79078 "Cell Cycle Checkpoints, Sus scrofa" + xref: Reactome:REACT_31789 "Cell Cycle Checkpoints, Dictyostelium discoideum" GO:0000080 : G1 phase of mitotic cell cycle - xref: Reactome:REACT_106229 "G1 Phase, Sus scrofa" + xref: Reactome:REACT_78866 "G1 Phase, Sus scrofa" GO:0000082 : G1/S transition of mitotic cell cycle - xref: Reactome:REACT_92675 "G1/S Transition, Sus scrofa" + xref: Reactome:REACT_85355 "G1/S Transition, Sus scrofa" GO:0000084 : S phase of mitotic cell cycle - xref: Reactome:REACT_31699 "S Phase, Sus scrofa" + xref: Reactome:REACT_85811 "S Phase, Sus scrofa" GO:0000085 : G2 phase of mitotic cell cycle - xref: Reactome:REACT_104865 "G2 Phase, Drosophila melanogaster" GO:0000086 : G2/M transition of mitotic cell cycle + xref: Reactome:REACT_114616 "G2/M Transition, Arabidopsis thaliana" GO:0000115 : regulation of transcription involved in S phase of mitotic cell cycle - xref: Reactome:REACT_871 "S-specific transcription in mitotic cell cycle, Homo sapiens" GO:0000116 : regulation of transcription involved in G2-phase of mitotic cell cycle + intersection_of: GO:0006355 + intersection_of: part_of GO:0000085 GO:0000117 : regulation of transcription involved in G2/M-phase of mitotic cell cycle - xref: Reactome:REACT_335 "G2/M-specific transcription in mitotic cell cycle, Homo sapiens" + intersection_of: GO:0006355 + intersection_of: part_of GO:0000086 GO:0000136 : alpha-1,6-mannosyltransferase complex - def: A large, multiprotein complex with alpha-1,6 mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins. + def: A large, multiprotein complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins. GO:0000148 : 1,3-beta-D-glucan synthase complex - def: A protein complex that catalyzes the transfer of a glucose group from UDP-glucose to a 1,3-beta-D-glucan chain. + def: A protein complex that catalyzes the transfer of a glucose group from UDP-glucose to a (1->3)-beta-D-glucan chain. + synonym: "(1->3)-beta-glucan synthase complex" EXACT [GOC:tb] GO:0000149 : SNARE binding - xref: Reactome:REACT_107850 "release of L-Glutamate at the synapse, Danio rerio" - xref: Reactome:REACT_28124 "Vamp7 associated Lysosome to Plasma membrane transport, Bos taurus" - xref: Reactome:REACT_110416 "Vamp8 associated secretory vesicle to plasma membrane transport, Arabidopsis thaliana" - xref: Reactome:REACT_105524 "Release of noradrenaline at the synapse, Xenopus tropicalis" - xref: Reactome:REACT_34098 "Release of acetylcholine at the synapse, Danio rerio" - xref: Reactome:REACT_28160 "Vamp8 associated secretory vesicle to plasma membrane transport, Oryza sativa" - xref: Reactome:REACT_107235 "Vamp8 associated secretory vesicle to plasma membrane transport, Dictyostelium discoideum" - xref: Reactome:REACT_110325 "Vamp8 associated secretory vesicle to plasma membrane transport, Bos taurus" - xref: Reactome:REACT_104117 "Release of noradrenaline at the synapse, Danio rerio" + xref: Reactome:REACT_115353 "Release of acetylcholine at the synapse, Xenopus tropicalis" + xref: Reactome:REACT_113753 "Exocytosis of Insulin, Danio rerio" + xref: Reactome:REACT_114225 "Noradrenalin synaptic vesicle docking and priming, Gallus gallus" + xref: Reactome:REACT_92466 "Vamp8 associated secretory vesicle to plasma membrane transport, Bos taurus" + xref: Reactome:REACT_114547 "Noradrenalin synaptic vesicle docking and priming, Caenorhabditis elegans" + xref: Reactome:REACT_107235 "Vamp2 associated secretory vesicle to plasma membrane transport, Dictyostelium discoideum" + xref: Reactome:REACT_112169 "Acetylcholine synaptic vesicle docking and priming, Caenorhabditis elegans" + xref: Reactome:REACT_115054 "release of L-Glutamate at the synapse, Xenopus tropicalis" + xref: Reactome:REACT_112728 "Release of noradrenaline at the synapse, Caenorhabditis elegans" + xref: Reactome:REACT_99237 "Vamp7 associated Lysosome to Plasma membrane transport, Bos taurus" + xref: Reactome:REACT_115130 "Acetylcholine synaptic vesicle docking and priming, Gallus gallus" + xref: Reactome:REACT_113606 "Glutamate synaptic vesicle docking and priming, Caenorhabditis elegans" GO:0000165 : MAPKKK cascade + xref: Reactome:REACT_113285 "RAF/MAP kinase cascade, Oryza sativa" + xref: Reactome:REACT_112235 "RAF/MAP kinase cascade, Dictyostelium discoideum" + xref: Reactome:REACT_112942 "RAF/MAP kinase cascade, Arabidopsis thaliana" GO:0000186 : activation of MAPKK activity + xref: Reactome:REACT_114228 "Prolonged ERK activation events, Dictyostelium discoideum" + xref: Reactome:REACT_113771 "Prolonged ERK activation events, Arabidopsis thaliana" + xref: Reactome:REACT_114817 "Prolonged ERK activation events, Oryza sativa" GO:0000187 : activation of MAPK activity - xref: Reactome:REACT_80936 "ERK activation, Caenorhabditis elegans" - xref: Reactome:REACT_93683 "activated TAK1 mediates p38 MAPK activation, Schizosaccharomyces pombe" - xref: Reactome:REACT_106895 "activated TAK1 mediates p38 MAPK activation, Caenorhabditis elegans" - xref: Reactome:REACT_96987 "activated TAK1 mediates p38 MAPK activation, Saccharomyces cerevisiae" + xref: Reactome:REACT_114778 "ERK activation, Arabidopsis thaliana" + xref: Reactome:REACT_113767 "ERK activation, Dictyostelium discoideum" + xref: Reactome:REACT_102664 "activated TAK1 mediates p38 MAPK activation, Caenorhabditis elegans" + xref: Reactome:REACT_101870 "ERK activation, Caenorhabditis elegans" + xref: Reactome:REACT_112664 "ERK activation, Oryza sativa" GO:0000189 : MAPK import into nucleus - xref: Reactome:REACT_47300 "Nuclear translocation of phospho-ERK-2 dimer, Sus scrofa" - xref: Reactome:REACT_98625 "Nuclear translocation of phospho-ERK-1 dimer, Saccharomyces cerevisiae" + xref: Reactome:REACT_115101 "Nuclear translocation of phospho-ERK-1 dimer, Arabidopsis thaliana" + xref: Reactome:REACT_95119 "Nuclear translocation of phospho-ERK-2 dimer, Sus scrofa" + xref: Reactome:REACT_113196 "Nuclear translocation of phospho-ERK-1 dimer, Oryza sativa" + xref: Reactome:REACT_32259 "Nuclear translocation of phospho-ERK-1 dimer, Saccharomyces cerevisiae" + xref: Reactome:REACT_114932 "Nuclear translocation of phospho-ERK-1 dimer, Dictyostelium discoideum" GO:0000216 : M/G1 transition of mitotic cell cycle - xref: Reactome:REACT_110210 "M/G1 Transition, Caenorhabditis elegans" - xref: Reactome:REACT_94911 "M/G1 Transition, Sus scrofa" + xref: Reactome:REACT_103126 "M/G1 Transition, Sus scrofa" + xref: Reactome:REACT_105126 "M/G1 Transition, Caenorhabditis elegans" GO:0000225 : N-acetylglucosaminylphosphatidylinositol deacetylase activity - xref: Reactome:REACT_89207 "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate, Saccharomyces cerevisiae" - xref: Reactome:REACT_31076 "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate, Sus scrofa" + xref: Reactome:REACT_98776 "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate, Sus scrofa" + xref: Reactome:REACT_114989 "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate, Arabidopsis thaliana" + xref: Reactome:REACT_32276 "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate, Saccharomyces cerevisiae" GO:0000236 : mitotic prometaphase - xref: Reactome:REACT_34037 "Mitotic Prometaphase, Caenorhabditis elegans" + xref: Reactome:REACT_114704 "Mitotic Prometaphase, Schizosaccharomyces pombe" + xref: Reactome:REACT_31385 "Mitotic Prometaphase, Caenorhabditis elegans" GO:0000248 : C-5 sterol desaturase activity - xref: Reactome:REACT_102297 "Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol, Arabidopsis thaliana" GO:0000250 : lanosterol synthase activity + xref: Reactome:REACT_114747 "Squalene 2,3-epoxide cyclizes, forming lanosterol, Arabidopsis thaliana" + xref: Reactome:REACT_112890 "Squalene 2,3-epoxide cyclizes, forming lanosterol, Oryza sativa" GO:0000252 : C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity - xref: Reactome:REACT_90196 "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one, Bos taurus" + xref: Reactome:REACT_112688 "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one, Mycobacterium tuberculosis" + xref: Reactome:REACT_114106 "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one, Oryza sativa" + xref: Reactome:REACT_112854 "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone), Schizosaccharomyces pombe" + xref: Reactome:REACT_112960 "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone), Saccharomyces cerevisiae" + xref: Reactome:REACT_114356 "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone), Dictyostelium discoideum" + xref: Reactome:REACT_113553 "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one, Saccharomyces cerevisiae" + xref: Reactome:REACT_113373 "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one, Dictyostelium discoideum" + xref: Reactome:REACT_112995 "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one, Schizosaccharomyces pombe" + xref: Reactome:REACT_113072 "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone), Oryza sativa" + xref: Reactome:REACT_115015 "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one, Arabidopsis thaliana" + xref: Reactome:REACT_115441 "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone), Arabidopsis thaliana" + xref: Reactome:REACT_106602 "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one, Bos taurus" + xref: Reactome:REACT_112771 "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one, Escherichia coli" GO:0000253 : 3-keto sterol reductase activity - xref: Reactome:REACT_97693 "Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol), Sus scrofa" + xref: Reactome:REACT_82943 "Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol), Sus scrofa" GO:0000254 : C-4 methylsterol oxidase activity - xref: Reactome:REACT_93636 "4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol, Bos taurus" + xref: Reactome:REACT_97328 "4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol, Bos taurus" + xref: Reactome:REACT_112865 "4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol, Xenopus tropicalis" + xref: Reactome:REACT_115505 "4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol, Xenopus tropicalis" GO:0000278 : mitotic cell cycle - xref: Reactome:REACT_103627 "Cell Cycle, Mitotic, Sus scrofa" + xref: Reactome:REACT_104035 "Cell Cycle, Mitotic, Sus scrofa" GO:0000288 : nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay - xref: Reactome:REACT_81082 "Deadenylation-dependent mRNA decay, Plasmodium falciparum" + xref: Reactome:REACT_105200 "Deadenylation-dependent mRNA decay, Plasmodium falciparum" GO:0000289 : nuclear-transcribed mRNA poly(A) tail shortening + xref: Reactome:REACT_111968 "Deadenylation of mRNA, Drosophila melanogaster" GO:0000295 : adenine nucleotide transmembrane transporter activity + xref: Reactome:REACT_113419 "PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP, Oryza sativa" GO:0000309 : nicotinamide-nucleotide adenylyltransferase activity - xref: Reactome:REACT_108730 "Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT1], Danio rerio" + xref: Reactome:REACT_114828 "Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT2], Saccharomyces cerevisiae" + xref: Reactome:REACT_115028 "Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT1], Dictyostelium discoideum" + xref: Reactome:REACT_112138 "Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT2], Arabidopsis thaliana" + xref: Reactome:REACT_114383 "Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT3], Dictyostelium discoideum" + xref: Reactome:REACT_112385 "Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT2], Oryza sativa" + xref: Reactome:REACT_114560 "Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT2], Schizosaccharomyces pombe" GO:0000387 : spliceosomal snRNP assembly - xref: Reactome:REACT_94555 "snRNP complex assembly, Sus scrofa" - xref: Reactome:REACT_88299 "snRNA Cap hypermethylation, Sus scrofa" - xref: Reactome:REACT_92577 "snRNP:Snurportin complex formation, Sus scrofa" + xref: Reactome:REACT_112455 "Loading and methylation of Sm proteins onto SMN Complexes, Xenopus tropicalis" GO:0000398 : nuclear mRNA splicing, via spliceosome - xref: Reactome:REACT_90009 "mRNA Splicing - Minor Pathway, Dictyostelium discoideum" + xref: Reactome:REACT_114738 "mRNA Splicing - Major Pathway, Taeniopygia guttata" + xref: Reactome:REACT_112200 "mRNA Splicing - Major Pathway, Arabidopsis thaliana" + xref: Reactome:REACT_34020 "mRNA Splicing - Minor Pathway, Dictyostelium discoideum" + xref: Reactome:REACT_114266 "mRNA Splicing - Major Pathway, Oryza sativa" GO:0000703 : oxidized pyrimidine base lesion DNA N-glycosylase activity - xref: Reactome:REACT_99711 "Cleavage of cytosine glycol by hNTH1 glycosylase, Saccharomyces cerevisiae" - xref: Reactome:REACT_104639 "Cleavage of dihydrouracil by hNTH1 glycosylase, Saccharomyces cerevisiae" - xref: Reactome:REACT_32746 "Cleavage of formamidopyrimidine by hNTH1 glycosylase, Sus scrofa" - xref: Reactome:REACT_106209 "Cleavage of thymine glycol by hNTH1 glycosylase, Saccharomyces cerevisiae" - xref: Reactome:REACT_86722 "Cleavage of cytosine glycol by hNTH1 glycosylase, Bos taurus" - xref: Reactome:REACT_108989 "Cleavage of formamidopyrimidine by hNTH1 glycosylase, Saccharomyces cerevisiae" + xref: Reactome:REACT_107207 "Cleavage of cytosine glycol by hNTH1 glycosylase, Bos taurus" + xref: Reactome:REACT_78343 "Cleavage of formamidopyrimidine by hNTH1 glycosylase, Sus scrofa" + xref: Reactome:REACT_103837 "Cleavage of formamidopyrimidine by hNTH1 glycosylase, Saccharomyces cerevisiae" + xref: Reactome:REACT_104266 "Cleavage of thymine glycol by hNTH1 glycosylase, Saccharomyces cerevisiae" + xref: Reactome:REACT_87055 "Cleavage of cytosine glycol by hNTH1 glycosylase, Saccharomyces cerevisiae" + xref: Reactome:REACT_78298 "Cleavage of dihydrouracil by hNTH1 glycosylase, Saccharomyces cerevisiae" GO:0000715 : nucleotide-excision repair, DNA damage recognition + xref: Reactome:REACT_115249 "DNA Damage Recognition in GG-NER, Xenopus tropicalis" + xref: Reactome:REACT_112311 "DNA Damage Recognition in GG-NER, Caenorhabditis elegans" GO:0000716 : transcription-coupled nucleotide-excision repair, DNA damage recognition - xref: Reactome:REACT_34608 "RNA Pol II is blocked by the lesion leading to reduced transcription, Saccharomyces cerevisiae" + xref: Reactome:REACT_103224 "RNA Pol II is blocked by the lesion leading to reduced transcription, Saccharomyces cerevisiae" GO:0000717 : nucleotide-excision repair, DNA duplex unwinding + xref: Reactome:REACT_113177 "Formation of open bubble structure in DNA by helicases, Caenorhabditis elegans" GO:0000718 : nucleotide-excision repair, DNA damage removal - xref: Reactome:REACT_86542 "Dual incision reaction in GG-NER, Sus scrofa" + xref: Reactome:REACT_89200 "Dual incision reaction in GG-NER, Sus scrofa" GO:0000722 : telomere maintenance via recombination - xref: Reactome:REACT_110309 "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere, Saccharomyces cerevisiae" - xref: Reactome:REACT_92815 "Telomere C-strand synthesis initiation, Schizosaccharomyces pombe" - xref: Reactome:REACT_78865 "Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere, Dictyostelium discoideum" - xref: Reactome:REACT_97374 "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere, Saccharomyces cerevisiae" - xref: Reactome:REACT_104853 "Formation of the Flap Intermediate on the C-strand, Schizosaccharomyces pombe" - xref: Reactome:REACT_96478 "RFC dissociates after sliding clamp formation on the C-strand of the telomere, Plasmodium falciparum" - xref: Reactome:REACT_77644 "Telomere C-strand synthesis initiation, Plasmodium falciparum" - xref: Reactome:REACT_81386 "RFC binding displaces Pol Alpha on the C-strand of the telomere, Schizosaccharomyces pombe" - xref: Reactome:REACT_107049 "Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere, Saccharomyces cerevisiae" + xref: Reactome:REACT_99836 "Telomere C-strand synthesis initiation, Plasmodium falciparum" + xref: Reactome:REACT_77906 "RFC dissociates after sliding clamp formation on the C-strand of the telomere, Plasmodium falciparum" + xref: Reactome:REACT_97849 "Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere, Dictyostelium discoideum" + xref: Reactome:REACT_110741 "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere, Saccharomyces cerevisiae" + xref: Reactome:REACT_103350 "Telomere C-strand synthesis initiation, Schizosaccharomyces pombe" + xref: Reactome:REACT_96454 "Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere, Saccharomyces cerevisiae" + xref: Reactome:REACT_98885 "Formation of the Flap Intermediate on the C-strand, Schizosaccharomyces pombe" + xref: Reactome:REACT_81258 "RFC binding displaces Pol Alpha on the C-strand of the telomere, Schizosaccharomyces pombe" + xref: Reactome:REACT_79977 "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere, Saccharomyces cerevisiae" GO:0000723 : telomere maintenance - xref: Reactome:REACT_104812 "Packaging Of Telomere Ends, Gallus gallus" + xref: Reactome:REACT_115102 "Packaging Of Telomere Ends, Canis familiaris" + xref: Reactome:REACT_115503 "Packaging Of Telomere Ends, Danio rerio" GO:0000724 : double-strand break repair via homologous recombination - xref: Reactome:REACT_30961 "Homologous Recombination Repair, Schizosaccharomyces pombe" + xref: Reactome:REACT_80576 "Homologous Recombination Repair, Schizosaccharomyces pombe" GO:0000730 : DNA recombinase assembly - xref: Reactome:REACT_99307 "Assembly of the RAD51-ssDNA nucleoprotein complex, Sus scrofa" + xref: Reactome:REACT_79561 "Assembly of the RAD51-ssDNA nucleoprotein complex, Sus scrofa" GO:0000826 : inositol pyrophosphate synthase activity - def: Catalysis of the phosphorylation of inositol phosphates which possess diphosphate bonds. + def: OBSOLETE. Catalysis of the phosphorylation of inositol phosphates which possess diphosphate bonds. + comment: This term was made obsolete because it is incorrectly defined; 'inositol pyrophosphate' is a inositol derivative to which one (or more) pyrophosphate moieties are attached. 'Inositol pyrophosphate synthase' refers to a class of enzymes that catalyze various different reactions that result in the formation of an IP, so one cannot formulate a general reaction for them. - is_a: GO:0004428 - is_a: GO:0016776 + is_obsolete: true + consider: GO:0052746 GO:0000827 : inositol 1,3,4,5,6-pentakisphosphate kinase activity - is_a: GO:0000826 + is_a: GO:0016776 GO:0000828 : inositol hexakisphosphate kinase activity - is_a: GO:0000826 + is_a: GO:0016776 GO:0000829 : inositol heptakisphosphate kinase activity - is_a: GO:0000826 + is_a: GO:0016776 GO:0001504 : neurotransmitter uptake - xref: Reactome:REACT_34341 "Neurotransmitter uptake and Metabolism In Glial Cells, Sus scrofa" + xref: Reactome:REACT_89424 "Neurotransmitter uptake and Metabolism In Glial Cells, Sus scrofa" + xref: Reactome:REACT_114027 "Neurotransmitter uptake and Metabolism In Glial Cells, Staphylococcus aureus N315" GO:0001532 : interleukin-21 receptor activity - is_a: GO:0019977 + relationship: has_part GO:0019977 GO:0001572 : lactosylceramide biosynthetic process - def: The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal beta(1,4)Glc beta(1,1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides. + def: The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides. GO:0001575 : globoside metabolic process - def: The chemical reactions and pathways involving globosides, globotetraosylceramides, ceramides containing a core structure of GalNAc-beta-(1,3)-Gal-alpha(1,4)Glc(I). Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes. + def: The chemical reactions and pathways involving globosides, globotetraosylceramides, ceramides containing a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I). Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes. GO:0001576 : globoside biosynthetic process - def: The chemical reactions and pathways resulting in the formation of a ceramide with a core structure of GalNAc-beta-(1,3)-Gal-alpha(1,4)Glc(I). + def: The chemical reactions and pathways resulting in the formation of a ceramide with a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I). GO:0001607 : neuromedin U receptor activity - is_a: GO:0042924 + relationship: has_part GO:0042924 GO:0001614 : purinergic nucleotide receptor activity + relationship: has_part GO:0017076 GO:0001621 : ADP receptor activity + relationship: has_part GO:0043531 GO:0001646 : cAMP receptor activity - is_a: GO:0030552 + relationship: has_part GO:0030552 GO:0001653 : peptide receptor activity - is_a: GO:0042277 + relationship: has_part GO:0042277 GO:0001665 : alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity - def: Catalysis of the reaction: CMP-N-acetylneuraminate + glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein = CMP + glycano-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein. + def: Catalysis of the reaction: CMP-N-acetylneuraminate + glycano-(1->3)-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein = CMP + glycano-[(2->6)-alpha-N-acetylneuraminyl]-(N-acetyl-D-galactosaminyl)-glycoprotein. GO:0001734 : mRNA (N6-adenosine)-methyltransferase activity - xref: Reactome:REACT_85125 "Internal Methylation of mRNA, Saccharomyces cerevisiae" + xref: Reactome:REACT_85371 "Internal Methylation of mRNA, Saccharomyces cerevisiae" GO:0001792 : polymeric immunoglobulin receptor activity - is_a: GO:0001790 + relationship: has_part GO:0001790 GO:0001793 : IgM receptor activity - is_a: GO:0001791 + relationship: has_part GO:0001791 GO:0001844 : protein insertion into mitochondrial membrane involved in induction of apoptosis - xref: Reactome:REACT_93779 "Translocation of PUMA protein to mitochondria, Canis familiaris" + xref: Reactome:REACT_113968 "Translocation of NOXA to mitochondria, Sus scrofa" + xref: Reactome:REACT_112264 "Translocation of activated BAD protein to mitochondria, Xenopus tropicalis" + xref: Reactome:REACT_112484 "Translocation of NOXA to mitochondria, Mus musculus" + xref: Reactome:REACT_115488 "Translocation of NOXA to mitochondria, Canis familiaris" + xref: Reactome:REACT_113120 "Translocation of BIM to mitochondria, Xenopus tropicalis" + xref: Reactome:REACT_112773 "Translocation of NOXA to mitochondria, Rattus norvegicus" GO:0001847 : opsonin receptor activity - is_a: GO:0001846 + relationship: has_part GO:0001846 GO:0001857 : complement component C1q receptor activity - is_a: GO:0001849 + relationship: has_part GO:0001849 GO:0001858 : complement component iC3b receptor activity - is_a: GO:0001852 + relationship: has_part GO:0001852 GO:0001859 : complement component C3dg receptor activity + relationship: has_part GO:0001853 GO:0001860 : complement component C3d receptor activity + relationship: has_part GO:0001854 GO:0001861 : complement component C4b receptor activity - is_a: GO:0001855 + relationship: has_part GO:0001855 GO:0001863 : collectin receptor activity + relationship: has_part GO:0001862 GO:0001867 : complement activation, lectin pathway - xref: Reactome:REACT_101763 "Lectin pathway of complement activation, Danio rerio" + xref: Reactome:REACT_114752 "Lectin pathway of complement activation, Canis familiaris" GO:0001872 : (1->3)-beta-D-glucan binding - name: 1,3-beta-D-glucan binding + name: (1->3)-beta-D-glucan binding - def: Interacting selectively and non-covalently with 1,3-beta-D-glucans. + def: Interacting selectively and non-covalently with (1->3)-beta-D-glucans. + synonym: "1,3-beta-D-glucan binding" EXACT [] GO:0001873 : polysaccharide receptor activity - is_a: GO:0030247 + relationship: has_part GO:0030247 GO:0001874 : (1->3)-beta-D-glucan receptor activity - name: 1,3-beta-D-glucan receptor activity + name: (1->3)-beta-D-glucan receptor activity - def: Combining with 1,3-beta-D glucans to initiate a change in cell activity. + def: Combining with (1->3)-beta-D-glucans to initiate a change in cell activity. - synonym: "(1->3)-beta-D-glucan receptor" EXACT [] + synonym: "beta-1,3-D-glucan receptor activity" EXACT [] + synonym: "1,3-beta-D-glucan receptor activity" EXACT [] + synonym: "(1,3)-beta-D-glucan receptor activity" EXACT [] - is_a: GO:0001872 + relationship: has_part GO:0001872 GO:0001875 : lipopolysaccharide receptor activity - is_a: GO:0001530 + relationship: has_part GO:0001530 GO:0001877 : lipoarabinomannan receptor activity - is_a: GO:0001876 + relationship: has_part GO:0001876 GO:0001888 : glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity - def: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1,3)-beta-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-(1,3)-beta-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-D-xylosyl-proteoglycan. + def: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan. + synonym: "UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1,3)-beta-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-D-xylosyl-proteoglycan 4IV-alpha-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.223] GO:0001962 : alpha-1,3-galactosyltransferase activity - def: Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-1,3-linkage. + def: Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-(1->3) linkage. GO:0002114 : interleukin-33 receptor activity - is_a: GO:0002113 + relationship: has_part GO:0002113 GO:0002120 : predatory behavior - name: predatory aggressive behavior + name: predatory behavior + synonym: "predatory aggressive behavior" EXACT [] + is_a: GO:0044366 GO:0002218 : activation of innate immune response - xref: Reactome:REACT_102126 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Xenopus tropicalis" - xref: Reactome:REACT_105549 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Gallus gallus" - xref: Reactome:REACT_95496 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Bos taurus" - xref: Reactome:REACT_95597 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Taeniopygia guttata" - xref: Reactome:REACT_75913 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Homo sapiens" - xref: Reactome:REACT_97582 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Canis familiaris" - xref: Reactome:REACT_91372 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Danio rerio" - xref: Reactome:REACT_109121 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Mus musculus" - xref: Reactome:REACT_99740 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Sus scrofa" - xref: Reactome:REACT_85368 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Rattus norvegicus" GO:0002224 : toll-like receptor signaling pathway - xref: Reactome:REACT_8006 "Toll Like Receptor TLR6:TLR2 Cascade, Chlamydia trachomatis" + xref: Reactome:REACT_8006 "Toll Like Receptor TLR6:TLR2 Cascade, Homo sapiens" GO:0002474 : antigen processing and presentation of peptide antigen via MHC class I + xref: Reactome:REACT_114442 "Class I MHC mediated antigen processing & presentation, Xenopus tropicalis" GO:0002479 : antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent + xref: Reactome:REACT_111056 "Cross-presentation of soluble exogenous antigens (endosomes), Homo sapiens" + xref: Reactome:REACT_111174 "Cross-presentation of particulate exogenous antigens (phagosomes), Homo sapiens" + xref: Reactome:REACT_111178 "ER-Phagosome pathway, Homo sapiens" GO:0002480 : antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent + xref: Reactome:REACT_111168 "Endosomal/Vacuolar pathway, Homo sapiens" GO:0002576 : platelet degranulation - xref: Reactome:REACT_86087 "Platelet degranulation, Escherichia coli" GO:0002755 : MyD88-dependent toll-like receptor signaling pathway - xref: Reactome:REACT_95157 "MyD88 cascade initiated on plasma membrane, Sus scrofa" - xref: Reactome:REACT_29988 "MyD88 cascade initiated on plasma membrane, Dictyostelium discoideum" - xref: Reactome:REACT_86913 "MyD88:Mal cascade initiated on plasma membrane, Caenorhabditis elegans" + xref: Reactome:REACT_32510 "MyD88:Mal cascade initiated on plasma membrane, Caenorhabditis elegans" + xref: Reactome:REACT_110031 "MyD88 cascade initiated on plasma membrane, Dictyostelium discoideum" + xref: Reactome:REACT_106952 "MyD88 cascade initiated on plasma membrane, Sus scrofa" GO:0002756 : MyD88-independent toll-like receptor signaling pathway - xref: Reactome:REACT_102363 "TRAF6 Mediated Induction of proinflammatory cytokines, Caenorhabditis elegans" + xref: Reactome:REACT_106039 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Mus musculus" + xref: Reactome:REACT_79777 "TRAF6 Mediated Induction of proinflammatory cytokines, Caenorhabditis elegans" + xref: Reactome:REACT_110980 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Danio rerio" + xref: Reactome:REACT_92796 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Taeniopygia guttata" + xref: Reactome:REACT_96392 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Bos taurus" + xref: Reactome:REACT_25148 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Homo sapiens" + xref: Reactome:REACT_97209 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Gallus gallus" + xref: Reactome:REACT_114143 "Viral dsRNA:TLR3:TRIF Complex Activates RIP1, Drosophila melanogaster" + xref: Reactome:REACT_98583 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Sus scrofa" + xref: Reactome:REACT_85389 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Rattus norvegicus" + xref: Reactome:REACT_99202 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Canis familiaris" + xref: Reactome:REACT_89370 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Xenopus tropicalis" GO:0003684 : damaged DNA binding - xref: Reactome:REACT_92706 "Stalling of DNA replication fork and RPA binding, Danio rerio" - xref: Reactome:REACT_6936 "Stalling of DNA replication fork and RPA binding, Homo sapiens" - xref: Reactome:REACT_95130 "Oxidative demethylation of 1-MeA damaged DNA By ABH3, Arabidopsis thaliana" - xref: Reactome:REACT_85779 "Oxidative demethylation of 1-MeA damaged DNA By ABH3, Oryza sativa" - xref: Reactome:REACT_105835 "Stalling of DNA replication fork and RPA binding, Gallus gallus" - xref: Reactome:REACT_96445 "Oxidative demethylation of 3-MeC damaged DNA By ABH3, Oryza sativa" - xref: Reactome:REACT_96895 "Oxidative demethylation of 3-MeC damaged DNA By ABH3, Arabidopsis thaliana" - xref: Reactome:REACT_90512 "Stalling of DNA replication fork and RPA binding, Bos taurus" - xref: Reactome:REACT_109137 "Stalling of DNA replication fork and RPA binding, Rattus norvegicus" - xref: Reactome:REACT_94983 "Stalling of DNA replication fork and RPA binding, Xenopus tropicalis" - xref: Reactome:REACT_28777 "Oxidative demethylation of 1-EtA damaged DNA By ABH3, Oryza sativa" - xref: Reactome:REACT_86410 "Stalling of DNA replication fork and RPA binding, Mus musculus" - xref: Reactome:REACT_77532 "Stalling of DNA replication fork and RPA binding, Canis familiaris" - xref: Reactome:REACT_103614 "Stalling of DNA replication fork and RPA binding, Taeniopygia guttata" - xref: Reactome:REACT_101374 "Oxidative demethylation of 1-EtA damaged DNA By ABH3, Arabidopsis thaliana" + xref: Reactome:REACT_113838 "Oxidative demethylation of 1-EtA damaged DNA By ABH2, Oryza sativa" + xref: Reactome:REACT_114851 "Oxidative demethylation of 3-MeC damaged DNA By ABH2, Oryza sativa" + xref: Reactome:REACT_95130 "Oxidative demethylation of 1-MeA damaged DNA By ABH2, Arabidopsis thaliana" + xref: Reactome:REACT_113713 "Oxidative demethylation of 1-EtA damaged DNA By ABH2, Arabidopsis thaliana" + xref: Reactome:REACT_85779 "Oxidative demethylation of 1-MeA damaged DNA By ABH2, Oryza sativa" + xref: Reactome:REACT_113582 "Oxidative demethylation of 3-MeC damaged DNA By ABH2, Arabidopsis thaliana" GO:0003689 : DNA clamp loader activity - xref: Reactome:REACT_85266 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Dictyostelium discoideum" + xref: Reactome:REACT_113703 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Gallus gallus" + xref: Reactome:REACT_33572 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Dictyostelium discoideum" GO:0003708 : retinoic acid receptor activity + relationship: has_part GO:0001972 GO:0003720 : telomerase activity - xref: Reactome:REACT_77982 "Elongation Of The Telomeric Chromosome End, Sus scrofa" - xref: Reactome:REACT_84958 "Elongation of Extended Telomeric Chromosome End, Saccharomyces cerevisiae" - xref: Reactome:REACT_30302 "Elongation Of The Telomeric Chromosome End, Dictyostelium discoideum" - xref: Reactome:REACT_101043 "Elongation Of The Telomeric Chromosome End, Saccharomyces cerevisiae" - xref: Reactome:REACT_32224 "Elongation of Extended Telomeric Chromosome End, Dictyostelium discoideum" + xref: Reactome:REACT_31549 "Elongation Of The Telomeric Chromosome End, Saccharomyces cerevisiae" + xref: Reactome:REACT_113385 "Elongation Of The Telomeric Chromosome End, Xenopus tropicalis" + xref: Reactome:REACT_114466 "Elongation of Extended Telomeric Chromosome End, Xenopus tropicalis" + xref: Reactome:REACT_30494 "Elongation Of The Telomeric Chromosome End, Sus scrofa" + xref: Reactome:REACT_104705 "Elongation of Extended Telomeric Chromosome End, Saccharomyces cerevisiae" GO:0003724 : RNA helicase activity - xref: Reactome:REACT_93046 "Cap-bound mRNA is activated by helicases, Rattus norvegicus" + xref: Reactome:REACT_112817 "Cap-bound mRNA is activated by helicases, Schizosaccharomyces pombe" GO:0003726 : double-stranded RNA adenosine deaminase activity + xref: Reactome:REACT_114900 "Deamination at C6 position of adenosine in Editosome (ADAR1), Arabidopsis thaliana" + xref: Reactome:REACT_115470 "Deamination at C6 position of adenosine in Editosome (ADAR1), Schizosaccharomyces pombe" + xref: Reactome:REACT_112024 "Deamination at C6 position of adenosine in Editosome (ADAR1), Saccharomyces cerevisiae" + xref: Reactome:REACT_112019 "Deamination at C6 position of adenosine in Editosome (ADAR1), Oryza sativa" + xref: Reactome:REACT_113770 "Deamination at C6 position of adenosine in Editosome (ADAR1), Caenorhabditis elegans" GO:0003743 : translation initiation factor activity + xref: Reactome:REACT_114676 "Ribosomal scanning, Gallus gallus" + xref: Reactome:REACT_112013 "Start codon recognition, Gallus gallus" + xref: Reactome:REACT_115451 "Start codon recognition, Bos taurus" + xref: Reactome:REACT_115079 "Start codon recognition, Rattus norvegicus" + xref: Reactome:REACT_115071 "Ribosomal scanning, Rattus norvegicus" GO:0003777 : microtubule motor activity - xref: Reactome:REACT_88648 "Axonal transport of NGF:Trk complexes, Rattus norvegicus" - xref: Reactome:REACT_83443 "Translocation of Insulin Secretory Granules to Cell Cortex, Gallus gallus" + xref: Reactome:REACT_115371 "Translocation of Insulin Secretory Granules to Cell Cortex, Gallus gallus" + xref: Reactome:REACT_113466 "Axonal transport of NGF:Trk complexes, Caenorhabditis elegans" GO:0003796 : lysozyme activity - def: Catalysis of the hydrolysis of the 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. + def: Catalysis of the hydrolysis of the beta-(1->4) linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. GO:0003810 : protein-glutamine gamma-glutamyltransferase activity + xref: Reactome:REACT_112902 "fibrin multimer -> fibrin multimer, crosslinked + NH4+, Xenopus tropicalis" + xref: Reactome:REACT_112367 "fibrin multimer -> fibrin multimer, crosslinked + NH4+, Sus scrofa" + xref: Reactome:REACT_112106 "fibrin multimer -> fibrin multimer, crosslinked + NH4+, Drosophila melanogaster" GO:0003826 : alpha-ketoacid dehydrogenase activity + xref: Reactome:REACT_113399 "a-ketoisocaproate, a-keto b-methylvalerate, or a-ketoisovalerate + CoA + NAD+ => isovaleryl-CoA, a-methylbutyryl-CoA, or isobuyryl-CoA + CO2 + NADH + H+, Mycobacterium tuberculosis" GO:0003828 : alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity - def: Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-2,8-alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-R. + def: Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R. - synonym: "CMP-NeuAc:LM1(alpha2-8) sialyltranferase activity" EXACT [EC:2.4.99.8] + synonym: "CMP-NeuAc:LM1(alpha-2,8) sialyltranferase activity" EXACT [EC:2.4.99.8] + synonym: "CMP-NeuAc:LM1 alpha-(2->8)-sialyltranferase activity" EXACT [EC:2.4.99.8] GO:0003829 : beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity - def: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R = UDP + beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R. + def: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R = UDP + beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-D-galactosaminyl-R. + synonym: "uridine diphosphoacetylglucosamine-mucin beta-(1,6)-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.102] GO:0003831 : beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity - def: Catalysis of the reaction: UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminylglycopeptide. + def: Catalysis of the reaction: UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide. - synonym: "beta-N-acetyl-beta1-4-galactosyltransferase activity" EXACT [EC:2.4.1.38] + synonym: "beta-N-acetyl-beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.38] + synonym: "beta-N-acetyl-beta-(1,4)-galactosyltransferase activity" EXACT [EC:2.4.1.38] GO:0003835 : beta-galactoside alpha-2,6-sialyltransferase activity - def: Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-acetyl-beta-D-glucosamine = CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine. + def: Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-acetyl-beta-D-glucosamine = CMP + alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine. GO:0003836 : beta-galactoside (CMP) alpha-2,3-sialyltransferase activity - def: Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R. + def: Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R = CMP + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R. GO:0003837 : beta-ureidopropionase activity + xref: Reactome:REACT_115012 "beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2, Schizosaccharomyces pombe" + xref: Reactome:REACT_112730 "beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2, Schizosaccharomyces pombe" GO:0003840 : gamma-glutamyltransferase activity - xref: Reactome:REACT_28642 "Cleavage of the gamma-glutamyl bond of LTC4 forms LTD4, Drosophila melanogaster" + xref: Reactome:REACT_114722 "Cleavage of the gamma-glutamyl bond of LTC4 forms LTD4, Caenorhabditis elegans" GO:0003841 : 1-acylglycerol-3-phosphate O-acyltransferase activity + xref: Reactome:REACT_113184 "1-acyl-glycerol 3-phosphate + acyl-CoA => 1,2-diacyl-glycerol 3-phosphate + CoASH, Dictyostelium discoideum" + xref: Reactome:REACT_113260 "1-acyl-glycerol 3-phosphate + acyl-CoA => 1,2-diacyl-glycerol 3-phosphate + CoASH, Arabidopsis thaliana" + xref: Reactome:REACT_115377 "1-acyl-glycerol 3-phosphate + acyl-CoA => 1,2-diacyl-glycerol 3-phosphate + CoASH, Caenorhabditis elegans" GO:0003843 : 1,3-beta-D-glucan synthase activity - def: Catalysis of the reaction: UDP-glucose + 1,3-beta-D-glucosyl(n) = UDP + 1,3-beta-D-glucosyl(n+1). + def: Catalysis of the reaction: UDP-glucose + [(1->3)-beta-D-glucosyl](n) = UDP + [(1->3)-beta-D-glucosyl](n+1). GO:0003844 : 1,4-alpha-glucan branching enzyme activity - def: Catalysis of the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxyl group in a similar glucan chain. + def: Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxyl group in a similar glucan chain. + xref: Reactome:REACT_115406 "poly((1,4)-alpha-D-glucosyl) glycogenin => glycogen-glycogenin, Arabidopsis thaliana" GO:0003845 : 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity - xref: Reactome:REACT_96314 "Oxidation of cortisol to yield cortisone, Mycobacterium tuberculosis" + xref: Reactome:REACT_114165 "Oxidation of cortisol to yield cortisone, Plasmodium falciparum" GO:0003854 : 3-beta-hydroxy-delta5-steroid dehydrogenase activity + xref: Reactome:REACT_115303 "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one, Mycobacterium tuberculosis" + xref: Reactome:REACT_114777 "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one, Mycobacterium tuberculosis" + xref: Reactome:REACT_115275 "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one, Escherichia coli" + xref: Reactome:REACT_113772 "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one, Escherichia coli" + xref: Reactome:REACT_113096 "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione, Mycobacterium tuberculosis" + xref: Reactome:REACT_112248 "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione, Escherichia coli" + xref: Reactome:REACT_114921 "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one, Mycobacterium tuberculosis" + xref: Reactome:REACT_113257 "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one, Escherichia coli" + xref: Reactome:REACT_111989 "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol, Mycobacterium tuberculosis" + xref: Reactome:REACT_114424 "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol, Escherichia coli" GO:0003857 : 3-hydroxyacyl-CoA dehydrogenase activity - xref: Reactome:REACT_28990 "(S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H, Escherichia coli" - xref: Reactome:REACT_110368 "3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+, Mycobacterium tuberculosis" - xref: Reactome:REACT_106559 "(24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA, Mycobacterium tuberculosis" - xref: Reactome:REACT_106616 "(24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA, Mycobacterium tuberculosis" - xref: Reactome:REACT_90995 "(24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA, Saccharomyces cerevisiae" - xref: Reactome:REACT_100712 "(S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H, Caenorhabditis elegans" - xref: Reactome:REACT_104037 "(S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H, Caenorhabditis elegans" - xref: Reactome:REACT_106331 "(S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H, Caenorhabditis elegans" - xref: Reactome:REACT_98365 "(S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H, Escherichia coli" - xref: Reactome:REACT_106409 "alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+, Caenorhabditis elegans" - xref: Reactome:REACT_51199 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Bos taurus" + xref: Reactome:REACT_99158 "(S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H, Caenorhabditis elegans" + xref: Reactome:REACT_110947 "(S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H, Caenorhabditis elegans" + xref: Reactome:REACT_101468 "(S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H, Caenorhabditis elegans" + xref: Reactome:REACT_113301 "(S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H, Staphylococcus aureus N315" + xref: Reactome:REACT_103002 "alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+, Caenorhabditis elegans" + xref: Reactome:REACT_113705 "(S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H, Staphylococcus aureus N315" + xref: Reactome:REACT_81715 "(24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA, Saccharomyces cerevisiae" + xref: Reactome:REACT_112490 "(S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H, Staphylococcus aureus N315" + xref: Reactome:REACT_99776 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Bos taurus" + xref: Reactome:REACT_115146 "(S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H, Staphylococcus aureus N315" + xref: Reactome:REACT_115227 "(S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H, Staphylococcus aureus N315" GO:0003858 : 3-hydroxybutyrate dehydrogenase activity - xref: Reactome:REACT_92932 "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+, Oryza sativa" - xref: Reactome:REACT_103885 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Canis familiaris" - xref: Reactome:REACT_89789 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Escherichia coli" - xref: Reactome:REACT_78212 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Sus scrofa" - xref: Reactome:REACT_32814 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Rattus norvegicus" - xref: Reactome:REACT_86958 "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+, Saccharomyces cerevisiae" - xref: Reactome:REACT_82478 "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+, Arabidopsis thaliana" - xref: Reactome:REACT_100598 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Taeniopygia guttata" - xref: Reactome:REACT_108608 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Danio rerio" - xref: Reactome:REACT_100701 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Gallus gallus" - xref: Reactome:REACT_84490 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Schizosaccharomyces pombe" - xref: Reactome:REACT_85059 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Xenopus tropicalis" - xref: Reactome:REACT_81394 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Mycobacterium tuberculosis" - xref: Reactome:REACT_91128 "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+, Dictyostelium discoideum" - xref: Reactome:REACT_97350 "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+, Schizosaccharomyces pombe" - xref: Reactome:REACT_103337 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Saccharomyces cerevisiae" - xref: Reactome:REACT_32582 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Dictyostelium discoideum" - xref: Reactome:REACT_32549 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Oryza sativa" - xref: Reactome:REACT_631 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Homo sapiens" - xref: Reactome:REACT_81074 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Mus musculus" - xref: Reactome:REACT_108694 "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+, Mycobacterium tuberculosis" - xref: Reactome:REACT_101032 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Arabidopsis thaliana" - xref: Reactome:REACT_34160 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Drosophila melanogaster" - xref: Reactome:REACT_95531 "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+, Drosophila melanogaster" - xref: Reactome:REACT_31121 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Bos taurus" + xref: Reactome:REACT_104408 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Sus scrofa" + xref: Reactome:REACT_108608 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Danio rerio" + xref: Reactome:REACT_89789 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Escherichia coli" + xref: Reactome:REACT_100598 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Taeniopygia guttata" + xref: Reactome:REACT_631 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Homo sapiens" + xref: Reactome:REACT_32814 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Rattus norvegicus" + xref: Reactome:REACT_85059 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Xenopus tropicalis" + xref: Reactome:REACT_103885 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Canis familiaris" + xref: Reactome:REACT_31121 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Bos taurus" + xref: Reactome:REACT_81074 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Mus musculus" + xref: Reactome:REACT_100701 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Gallus gallus" GO:0003860 : 3-hydroxyisobutyryl-CoA hydrolase activity + xref: Reactome:REACT_115031 "beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA, Arabidopsis thaliana" GO:0003870 : 5-aminolevulinate synthase activity - xref: Reactome:REACT_103620 "Succinyl CoA and glycine condense to form 5-aminolevulinate (ALA), Schizosaccharomyces pombe" + xref: Reactome:REACT_98622 "Succinyl CoA and glycine condense to form 5-aminolevulinate (ALA), Schizosaccharomyces pombe" GO:0003872 : 6-phosphofructokinase activity - xref: Reactome:REACT_93423 "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP, Dictyostelium discoideum" + xref: Reactome:REACT_112049 "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP, Oryza sativa" + xref: Reactome:REACT_96419 "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP, Dictyostelium discoideum" + xref: Reactome:REACT_114580 "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP, Arabidopsis thaliana" GO:0003874 : 6-pyruvoyltetrahydropterin synthase activity + xref: Reactome:REACT_111082 "DHNTP is dephosphorylated by PTPS to PTHP, Homo sapiens" GO:0003876 : AMP deaminase activity - xref: Reactome:REACT_85426 "AMP + H2O => IMP + NH3 [AMPD], Schizosaccharomyces pombe" GO:0003883 : CTP synthase activity - xref: Reactome:REACT_33487 "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2], Sus scrofa" + xref: Reactome:REACT_98846 "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2], Sus scrofa" GO:0003884 : D-amino-acid oxidase activity + xref: Reactome:REACT_113962 "glycine + O2 => glyoxylate + H2O2 + NH4+, Schizosaccharomyces pombe" + xref: Reactome:REACT_115482 "glycine + O2 => glyoxylate + H2O2 + NH4+, Caenorhabditis elegans" + xref: Reactome:REACT_115360 "glycine + O2 => glyoxylate + H2O2 + NH4+, Mycobacterium tuberculosis" + xref: Reactome:REACT_114219 "glycine + O2 => glyoxylate + H2O2 + NH4+, Drosophila melanogaster" GO:0003886 : DNA (cytosine-5-)-methyltransferase activity - synonym: "DNA cytosine c5 methylase activity" EXACT [EC:2.1.1.37] GO:0003887 : DNA-directed DNA polymerase activity - xref: Reactome:REACT_110309 "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere, Saccharomyces cerevisiae" - xref: Reactome:REACT_80652 "Elongation by Pol eta, Saccharomyces cerevisiae" - xref: Reactome:REACT_78710 "Elongation by HREV1 protein, Saccharomyces cerevisiae" - xref: Reactome:REACT_79973 "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin, Dictyostelium discoideum" - xref: Reactome:REACT_103629 "Misinsertion of bases opposite to the lesion by HREV1, Saccharomyces cerevisiae" - xref: Reactome:REACT_76968 "POL Beta mediated incorporation of the first replacement nucleotide, Bos taurus" - xref: Reactome:REACT_107698 "Insertion of correct bases opposite to the lesion by Pol eta, Saccharomyces cerevisiae" + xref: Reactome:REACT_112231 "Elongation by Pol zeta complex, Xenopus tropicalis" + xref: Reactome:REACT_84407 "Elongation by HREV1 protein, Saccharomyces cerevisiae" + xref: Reactome:REACT_105070 "Insertion of correct bases opposite to the lesion by Pol eta, Saccharomyces cerevisiae" + xref: Reactome:REACT_28865 "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin, Dictyostelium discoideum" + xref: Reactome:REACT_94622 "POL Beta mediated incorporation of the first replacement nucleotide, Bos taurus" + xref: Reactome:REACT_90511 "Misinsertion of bases opposite to the lesion by HREV1, Saccharomyces cerevisiae" + xref: Reactome:REACT_83674 "Elongation by Pol eta, Saccharomyces cerevisiae" + xref: Reactome:REACT_112289 "Elongation by Pol zeta complex, Taeniopygia guttata" + xref: Reactome:REACT_112468 "Elongation by Pol zeta complex, Dictyostelium discoideum" + xref: Reactome:REACT_79977 "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere, Saccharomyces cerevisiae" GO:0003899 : DNA-directed RNA polymerase activity - xref: Reactome:REACT_99106 "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Canis familiaris" - xref: Reactome:REACT_29713 "Addition of nucleotides between position +11 and +30, Saccharomyces cerevisiae" - xref: Reactome:REACT_102116 "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Bos taurus" - xref: Reactome:REACT_97374 "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere, Saccharomyces cerevisiae" - xref: Reactome:REACT_110838 "Addition of the third nucleotide on the nascent transcript, Bos taurus" - xref: Reactome:REACT_80211 "Elongation of pre-rRNA transcript, Bos taurus" - xref: Reactome:REACT_108565 "Pol II mediated transcription of microRNA genes, Caenorhabditis elegans" - xref: Reactome:REACT_88953 "Addition of the third nucleotide on the nascent transcript, Canis familiaris" - xref: Reactome:REACT_79401 "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Schizosaccharomyces pombe" - xref: Reactome:REACT_84507 "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin, Dictyostelium discoideum" + xref: Reactome:REACT_109090 "Addition of nucleotides between position +11 and +30, Saccharomyces cerevisiae" + xref: Reactome:REACT_28467 "Pol II mediated transcription of microRNA genes, Caenorhabditis elegans" + xref: Reactome:REACT_113943 "Elongation of pre-rRNA transcript, Gallus gallus" + xref: Reactome:REACT_110741 "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere, Saccharomyces cerevisiae" + xref: Reactome:REACT_80464 "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin, Dictyostelium discoideum" + xref: Reactome:REACT_78158 "Elongation of pre-rRNA transcript, Bos taurus" + xref: Reactome:REACT_112968 "Elongation of pre-rRNA transcript, Oryza sativa" + xref: Reactome:REACT_31554 "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Schizosaccharomyces pombe" + xref: Reactome:REACT_112737 "Addition of Nucleotides 5 through 9 on the growing Transcript, Gallus gallus" GO:0003905 : alkylbase DNA N-glycosylase activity - def: Catalysis of the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine. Enzymes with this activity recognize and remove alkylated purines and pyrimidines by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic or apyrimidinic (AP) site. + def: Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site. GO:0003906 : DNA-(apurinic or apyrimidinic site) lyase activity - xref: Reactome:REACT_86232 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Sus scrofa" + xref: Reactome:REACT_85754 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Sus scrofa" GO:0003908 : methylated-DNA-[protein]-cysteine S-methyltransferase activity - xref: Reactome:REACT_102469 "MGMT/hAGT mediated DNA Damage Reversal, Escherichia coli" - xref: Reactome:REACT_87264 "MGMT/hAGT mediated DNA Damage Reversal, Sus scrofa" + xref: Reactome:REACT_108289 "MGMT/hAGT mediated DNA Damage Reversal, Sus scrofa" GO:0003909 : DNA ligase activity - xref: Reactome:REACT_102434 "Ligation of DNA and formation of Holliday structures following repair synthesis, Caenorhabditis elegans" - xref: Reactome:REACT_101158 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Saccharomyces cerevisiae" - xref: Reactome:REACT_80904 "Ligation of DNA at sites of patch replacement, Sus scrofa" + xref: Reactome:REACT_113076 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Xenopus tropicalis" + xref: Reactome:REACT_112118 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Mus musculus" + xref: Reactome:REACT_114038 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Rattus norvegicus" + xref: Reactome:REACT_113851 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Bos taurus" + xref: Reactome:REACT_109841 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Saccharomyces cerevisiae" + xref: Reactome:REACT_31800 "Ligation of DNA at sites of patch replacement, Sus scrofa" + xref: Reactome:REACT_112246 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Sus scrofa" + xref: Reactome:REACT_114285 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Danio rerio" + xref: Reactome:REACT_113217 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Gallus gallus" + xref: Reactome:REACT_114706 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Taeniopygia guttata" + xref: Reactome:REACT_113661 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Canis familiaris" + xref: Reactome:REACT_82930 "Ligation of DNA and formation of Holliday structures following repair synthesis, Caenorhabditis elegans" GO:0003919 : FMN adenylyltransferase activity - xref: Reactome:REACT_79042 "FMN is futher phosphorylated to FAD, Drosophila melanogaster" GO:0003921 : GMP synthase activity + xref: Reactome:REACT_114078 "XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate, Xenopus tropicalis" GO:0003923 : GPI-anchor transamidase activity - xref: Reactome:REACT_97490 "uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide, Sus scrofa" - xref: Reactome:REACT_78112 "uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide, Bos taurus" + xref: Reactome:REACT_113833 "uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide, Xenopus tropicalis" + xref: Reactome:REACT_92319 "uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide, Bos taurus" + xref: Reactome:REACT_34799 "uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide, Sus scrofa" GO:0003924 : GTPase activity - xref: Reactome:REACT_92563 "Vesicle Uncoating, Caenorhabditis elegans" - xref: Reactome:REACT_108111 "Hydrolysis of eEF1A:GTP, Oryza sativa" - xref: Reactome:REACT_39715 "Vesicle Uncoating, Sus scrofa" - xref: Reactome:REACT_63828 "trans-Golgi Network Vesicle Scission, Caenorhabditis elegans" - xref: Reactome:REACT_100393 "Disassembly of COPII coated vesicle, Bos taurus" - xref: Reactome:REACT_80598 "Hydrolysis of eEF1A:GTP, Arabidopsis thaliana" - xref: Reactome:REACT_97130 "Disassembly of COPII coated vesicle, Rattus norvegicus" - xref: Reactome:REACT_86940 "Disassembly of COPII coated vesicle, Canis familiaris" - xref: Reactome:REACT_97625 "Adenylate cyclase increases the GTPase activity of Gi alpha, Dictyostelium discoideum" - xref: Reactome:REACT_104791 "Vesicle Uncoating, Schizosaccharomyces pombe" - xref: Reactome:REACT_96172 "Loss of Sar1b GTPase, Dictyostelium discoideum" - xref: Reactome:REACT_87519 "Hydrolysis of eEF1A:GTP, Taeniopygia guttata" - xref: Reactome:REACT_77877 "Loss of Sar1b GTPase, Caenorhabditis elegans" - xref: Reactome:REACT_82856 "G alpha (z) auto-inactivates by hydrolysing GTP to GDP, Caenorhabditis elegans" - xref: Reactome:REACT_31077 "Hydrolysis of eEF1A:GTP, Caenorhabditis elegans" - xref: Reactome:REACT_95550 "G alpha (z) auto-inactivates by hydrolysing GTP to GDP, Drosophila melanogaster" - xref: Reactome:REACT_30968 "Adenylate cyclase increases the GTPase activity of G alpha-olf, Dictyostelium discoideum" - xref: Reactome:REACT_32756 "G-protein alpha subunit is inactivated, Sus scrofa" - xref: Reactome:REACT_30005 "Adenylate cyclase increases the GTPase activity of G alpha-olf, Caenorhabditis elegans" - xref: Reactome:REACT_84312 "Adenylate cyclase increases the GTPase activity of Gi alpha, Caenorhabditis elegans" - xref: Reactome:REACT_105040 "Hydrolysis of eEF1A:GTP, Saccharomyces cerevisiae" - xref: Reactome:REACT_31604 "G-protein alpha subunit is inactivated, Saccharomyces cerevisiae" - xref: Reactome:REACT_99049 "Hydrolysis of eEF1A:GTP, Xenopus tropicalis" - xref: Reactome:REACT_93472 "Disassembly of COPII coated vesicle, Sus scrofa" - xref: Reactome:REACT_84776 "Loss of Sar1b GTPase, Sus scrofa" - xref: Reactome:REACT_89133 "Adenylaye cyclase increases the GTPase activity of G alpha-olf, Dictyostelium discoideum" + xref: Reactome:REACT_112104 "Endocytosis (internalization) of clathrin-coated vesicle, Sus scrofa" + xref: Reactome:REACT_114148 "G alpha (q) auto-inactivates by hydrolysing GTP to GDP, Schizosaccharomyces pombe" + xref: Reactome:REACT_114188 "Formation of clathrin coated vesicle, Sus scrofa" + xref: Reactome:REACT_113209 "G alpha (z) auto-inactivates by hydrolysing GTP to GDP, Schizosaccharomyces pombe" + xref: Reactome:REACT_111994 "G alpha (z) auto-inactivates by hydrolysing GTP to GDP, Xenopus tropicalis" + xref: Reactome:REACT_28065 "Vesicle Uncoating, Sus scrofa" + xref: Reactome:REACT_114824 "trans-Golgi Network Lysosomal Vesicle Scission, Taeniopygia guttata" + xref: Reactome:REACT_113954 "Endocytosis (internalization) of clathrin-coated vesicle, Schizosaccharomyces pombe" + xref: Reactome:REACT_115324 "Endocytosis (internalization) of clathrin-coated vesicle, Bos taurus" + xref: Reactome:REACT_113727 "G alpha (q) auto-inactivates by hydrolysing GTP to GDP, Saccharomyces cerevisiae" + xref: Reactome:REACT_112389 "Disassembly of COPII coated vesicle, Gallus gallus" + xref: Reactome:REACT_114384 "Hydrolysis of eEF1A:GTP, Gallus gallus" + xref: Reactome:REACT_112254 "Endocytosis (internalization) of clathrin-coated vesicle, Xenopus tropicalis" + xref: Reactome:REACT_112587 "trans-Golgi Network Vesicle Scission, Schizosaccharomyces pombe" + xref: Reactome:REACT_110931 "G-protein alpha subunit is inactivated, Sus scrofa" + xref: Reactome:REACT_113832 "Formation of clathrin coated vesicle, Bos taurus" + xref: Reactome:REACT_113058 "G alpha (s) auto-inactivates by hydrolysing GTP to GDP, Saccharomyces cerevisiae" + xref: Reactome:REACT_104739 "Loss of Sar1b GTPase, Dictyostelium discoideum" + xref: Reactome:REACT_105697 "G-protein alpha subunit is inactivated, Saccharomyces cerevisiae" + xref: Reactome:REACT_112671 "Vesicle Uncoating, Plasmodium falciparum" + xref: Reactome:REACT_93305 "Loss of Sar1b GTPase, Sus scrofa" + xref: Reactome:REACT_113912 "Hydrolysis of eEF1A:GTP, Bos taurus" + xref: Reactome:REACT_114379 "Formation of clathrin coated vesicle, Taeniopygia guttata" + xref: Reactome:REACT_34113 "Vesicle Uncoating, Schizosaccharomyces pombe" + xref: Reactome:REACT_114331 "trans-Golgi Network Vesicle Scission, Taeniopygia guttata" + xref: Reactome:REACT_114153 "Loss of Sar1b GTPase, Xenopus tropicalis" + xref: Reactome:REACT_115229 "G alpha (s) auto-inactivates by hydrolysing GTP to GDP, Schizosaccharomyces pombe" + xref: Reactome:REACT_112651 "Vesicle Uncoating, Xenopus tropicalis" + xref: Reactome:REACT_30707 "trans-Golgi Network Vesicle Scission, Caenorhabditis elegans" + xref: Reactome:REACT_114620 "Endocytosis (internalization) of clathrin-coated vesicle, Taeniopygia guttata" + xref: Reactome:REACT_114210 "G-protein alpha subunit is inactivated, Schizosaccharomyces pombe" + xref: Reactome:REACT_114532 "Formation of clathrin coated vesicle, Xenopus tropicalis" + xref: Reactome:REACT_84712 "Hydrolysis of eEF1A:GTP, Saccharomyces cerevisiae" + xref: Reactome:REACT_113952 "Formation of clathrin coated vesicle, Schizosaccharomyces pombe" GO:0003934 : GTP cyclohydrolase I activity + xref: Reactome:REACT_111143 "GCH1 reduces GTP to dihydroneopterin triphosphate, Homo sapiens" GO:0003937 : IMP cyclohydrolase activity - xref: Reactome:REACT_79931 "FAICAR => IMP + H2O, Caenorhabditis elegans" + xref: Reactome:REACT_101852 "FAICAR => IMP + H2O, Caenorhabditis elegans" GO:0003945 : N-acetyllactosamine synthase activity - synonym: "N-acetylglucosamine (beta1,4)galactosyltransferase activity" EXACT [EC:2.4.1.90] - synonym: "UDP-galactose:N-acetylglucosaminide beta1-4-galactosyltransferase activity" EXACT [EC:2.4.1.90] - synonym: "UDP-Gal:N-acetylglucosamine beta1-4-galactosyltransferase activity" EXACT [EC:2.4.1.90] - synonym: "beta-N-acetylglucosaminide beta1-4-galactosyltransferase activity" EXACT [EC:2.4.1.90] - synonym: "beta1-4GalT" RELATED [EC:2.4.1.90] - synonym: "beta1-4-galactosyltransferase activity" EXACT [EC:2.4.1.90] - synonym: "UDPgalactose:N-acetylglucosaminyl(beta1-4)galactosyltransferase activity" EXACT [EC:2.4.1.90] + synonym: "UDPgalactose:N-acetylglucosaminyl(beta-1,4)galactosyltransferase activity" EXACT [EC:2.4.1.90] + synonym: "beta-(1,4)-galactosyltransferase activity" EXACT [EC:2.4.1.90] + synonym: "UDP-Gal:N-acetylglucosamine beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.90] + synonym: "N-acetylglucosamine beta-(1,4)-galactosyltransferase activity" EXACT [EC:2.4.1.90] + synonym: "beta-1,4-GalT" RELATED [EC:2.4.1.90] + synonym: "beta-N-acetylglucosaminide beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.90] + synonym: "UDP-galactose:N-acetylglucosaminide beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.90] GO:0003951 : NAD+ kinase activity - xref: Reactome:REACT_97396 "NAD+ is phosphorylated to NADP+, Saccharomyces cerevisiae" - xref: Reactome:REACT_88583 "NAD+ is phosphorylated to NADP+, Staphylococcus aureus N315" - xref: Reactome:REACT_109385 "NAD+ is phosphorylated to NADP+, Schizosaccharomyces pombe" GO:0003952 : NAD+ synthase (glutamine-hydrolyzing) activity - xref: Reactome:REACT_98752 "Amidation of deamino-NAD+ to NAD+, Dictyostelium discoideum" + xref: Reactome:REACT_112596 "Amidation of deamino-NAD+ to NAD+, Xenopus tropicalis" + xref: Reactome:REACT_84016 "Amidation of deamino-NAD+ to NAD+, Dictyostelium discoideum" GO:0003961 : O-acetylhomoserine aminocarboxypropyltransferase activity + alt_id: GO:0019282 + synonym: "L-methionine anabolism, direct, from O-acetyl-L-homoserine" EXACT [GOC:mah] + synonym: "methionine biosynthetic process, direct, from O-acetyl-L-homoserine" EXACT [GOC:mah] + synonym: "L-methionine biosynthetic process, direct, from O-acetyl-L-homoserine" EXACT [] + synonym: "L-methionine formation, direct, from O-acetyl-L-homoserine" EXACT [GOC:mah] + synonym: "L-methionine synthesis, direct, from O-acetyl-L-homoserine" EXACT [GOC:mah] + relationship: part_of GO:0071266 GO:0003978 : UDP-glucose 4-epimerase activity - xref: Reactome:REACT_31187 "UDP-galactose <=> UDP-glucose, Mycobacterium tuberculosis" - xref: Reactome:REACT_29100 "UDP-galactose <=> UDP-glucose, Dictyostelium discoideum" + xref: Reactome:REACT_115000 "UDP-galactose <=> UDP-glucose, Arabidopsis thaliana" + xref: Reactome:REACT_94034 "UDP-galactose <=> UDP-glucose, Dictyostelium discoideum" + xref: Reactome:REACT_115411 "UDP-galactose <=> UDP-glucose, Oryza sativa" + xref: Reactome:REACT_115332 "UDP-galactose <=> UDP-glucose, Schizosaccharomyces pombe" GO:0003979 : UDP-glucose 6-dehydrogenase activity + xref: Reactome:REACT_112524 "UDP-glucose is oxidised to UDP-glucuronate, Escherichia coli" GO:0003985 : acetyl-CoA C-acetyltransferase activity - xref: Reactome:REACT_103568 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Drosophila melanogaster" - xref: Reactome:REACT_109899 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Bos taurus" - xref: Reactome:REACT_93946 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Drosophila melanogaster" - xref: Reactome:REACT_104958 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Mus musculus" - xref: Reactome:REACT_47 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Homo sapiens" - xref: Reactome:REACT_100461 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Danio rerio" - xref: Reactome:REACT_31739 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Xenopus tropicalis" - xref: Reactome:REACT_31976 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Xenopus tropicalis" - xref: Reactome:REACT_92663 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Schizosaccharomyces pombe" - xref: Reactome:REACT_105877 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Mycobacterium tuberculosis" - xref: Reactome:REACT_80937 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Saccharomyces cerevisiae" - xref: Reactome:REACT_32156 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Gallus gallus" - xref: Reactome:REACT_85622 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Taeniopygia guttata" - xref: Reactome:REACT_102563 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Rattus norvegicus" - xref: Reactome:REACT_79103 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Schizosaccharomyces pombe" - xref: Reactome:REACT_884 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Homo sapiens" - xref: Reactome:REACT_96819 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Plasmodium falciparum" - xref: Reactome:REACT_106542 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Dictyostelium discoideum" - xref: Reactome:REACT_85056 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Danio rerio" - xref: Reactome:REACT_105003 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Taeniopygia guttata" - xref: Reactome:REACT_28462 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Plasmodium falciparum" - xref: Reactome:REACT_84180 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Gallus gallus" - xref: Reactome:REACT_103940 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Canis familiaris" - xref: Reactome:REACT_97821 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Saccharomyces cerevisiae" - xref: Reactome:REACT_92854 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Mus musculus" - xref: Reactome:REACT_102319 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Mycobacterium tuberculosis" - xref: Reactome:REACT_28646 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Canis familiaris" - xref: Reactome:REACT_109820 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Dictyostelium discoideum" - xref: Reactome:REACT_79150 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Rattus norvegicus" - xref: Reactome:REACT_105426 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Bos taurus" + xref: Reactome:REACT_28646 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Canis familiaris" + xref: Reactome:REACT_28462 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Plasmodium falciparum" + xref: Reactome:REACT_114812 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Caenorhabditis elegans" + xref: Reactome:REACT_92663 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Schizosaccharomyces pombe" + xref: Reactome:REACT_93946 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Drosophila melanogaster" + xref: Reactome:REACT_31739 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Xenopus tropicalis" + xref: Reactome:REACT_102319 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Mycobacterium tuberculosis" + xref: Reactome:REACT_47 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Homo sapiens" + xref: Reactome:REACT_109899 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Bos taurus" + xref: Reactome:REACT_85056 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Danio rerio" + xref: Reactome:REACT_92854 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Mus musculus" + xref: Reactome:REACT_97821 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Saccharomyces cerevisiae" + xref: Reactome:REACT_100461 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Danio rerio" + xref: Reactome:REACT_104958 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Mus musculus" + xref: Reactome:REACT_113533 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Caenorhabditis elegans" + xref: Reactome:REACT_103940 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Canis familiaris" + xref: Reactome:REACT_102563 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Rattus norvegicus" + xref: Reactome:REACT_103568 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Drosophila melanogaster" + xref: Reactome:REACT_79103 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Schizosaccharomyces pombe" + xref: Reactome:REACT_97416 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Saccharomyces cerevisiae" + xref: Reactome:REACT_84180 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Gallus gallus" + xref: Reactome:REACT_85622 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Taeniopygia guttata" + xref: Reactome:REACT_105426 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Bos taurus" + xref: Reactome:REACT_106542 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Dictyostelium discoideum" + xref: Reactome:REACT_884 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Homo sapiens" + xref: Reactome:REACT_105003 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Taeniopygia guttata" + xref: Reactome:REACT_32156 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Gallus gallus" + xref: Reactome:REACT_79150 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Rattus norvegicus" + xref: Reactome:REACT_109820 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Dictyostelium discoideum" + xref: Reactome:REACT_112932 "alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA, Caenorhabditis elegans" + xref: Reactome:REACT_96819 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Plasmodium falciparum" + xref: Reactome:REACT_31976 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Xenopus tropicalis" + xref: Reactome:REACT_105877 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Mycobacterium tuberculosis" GO:0003986 : acetyl-CoA hydrolase activity - xref: Reactome:REACT_85181 "acetyl-CoA + H2O => acetate + CoASH, Sus scrofa" + xref: Reactome:REACT_89514 "acetyl-CoA + H2O => acetate + CoASH, Sus scrofa" GO:0003987 : acetate-CoA ligase activity - xref: Reactome:REACT_93730 "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic], Sus scrofa" + xref: Reactome:REACT_84415 "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic], Sus scrofa" + xref: Reactome:REACT_112167 "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic], Escherichia coli" GO:0003989 : acetyl-CoA carboxylase activity - xref: Reactome:REACT_88371 "Formation of Malonyl-CoA from Acetyl-CoA (muscle), Plasmodium falciparum" - xref: Reactome:REACT_78588 "acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate, Plasmodium falciparum" - xref: Reactome:REACT_77406 "acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate, Caenorhabditis elegans" - xref: Reactome:REACT_107532 "Formation of Malonyl-CoA from Acetyl-CoA (muscle), Bos taurus" - xref: Reactome:REACT_28888 "Formation of Malonyl-CoA from Acetyl-CoA (muscle), Caenorhabditis elegans" + xref: Reactome:REACT_104374 "Formation of Malonyl-CoA from Acetyl-CoA (muscle), Bos taurus" + xref: Reactome:REACT_114007 "Formation of Malonyl-CoA from Acetyl-CoA (muscle), Taeniopygia guttata" GO:0003993 : acid phosphatase activity - xref: Reactome:REACT_91017 "FMN can be hydrolyzed back to riboflavin, Bos taurus" + xref: Reactome:REACT_82194 "FMN can be hydrolyzed back to riboflavin, Bos taurus" GO:0003994 : aconitate hydratase activity - xref: Reactome:REACT_30425 "citrate <=> isocitrate, Escherichia coli" GO:0003995 : acyl-CoA dehydrogenase activity - xref: Reactome:REACT_77989 "Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2, Caenorhabditis elegans" - xref: Reactome:REACT_82039 "dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA, Caenorhabditis elegans" - xref: Reactome:REACT_28144 "lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2, Sus scrofa" - xref: Reactome:REACT_51199 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Bos taurus" + xref: Reactome:REACT_99180 "dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA, Caenorhabditis elegans" + xref: Reactome:REACT_113088 "lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2, Staphylococcus aureus N315" + xref: Reactome:REACT_82463 "lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2, Sus scrofa" + xref: Reactome:REACT_113123 "myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2, Staphylococcus aureus N315" + xref: Reactome:REACT_109051 "Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2, Caenorhabditis elegans" + xref: Reactome:REACT_114274 "palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2, Xenopus tropicalis" + xref: Reactome:REACT_99776 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Bos taurus" GO:0003997 : acyl-CoA oxidase activity - xref: Reactome:REACT_99262 "25(S) THCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA, Caenorhabditis elegans" - xref: Reactome:REACT_99038 "hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2, Dictyostelium discoideum" - xref: Reactome:REACT_78265 "25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA, Dictyostelium discoideum" - xref: Reactome:REACT_31895 "25(S) THCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA, Drosophila melanogaster" - xref: Reactome:REACT_88619 "25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA, Caenorhabditis elegans" - xref: Reactome:REACT_90244 "25(S) THCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA, Dictyostelium discoideum" - xref: Reactome:REACT_109839 "25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA, Drosophila melanogaster" + xref: Reactome:REACT_114247 "hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2, Caenorhabditis elegans" + xref: Reactome:REACT_115434 "hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2, Drosophila melanogaster" GO:0003999 : adenine phosphoribosyltransferase activity - xref: Reactome:REACT_89305 "Adenine + PRPP => AMP + PPi, Oryza sativa" - xref: Reactome:REACT_85316 "Adenine + PRPP => AMP + PPi, Arabidopsis thaliana" - xref: Reactome:REACT_31898 "Adenine + PRPP => AMP + PPi, Saccharomyces cerevisiae" + xref: Reactome:REACT_84345 "Adenine + PRPP => AMP + PPi, Saccharomyces cerevisiae" GO:0004000 : adenosine deaminase activity - xref: Reactome:REACT_29811 "(2'-deoxy)adenosine + H2O => (2'-deoxy)inosine + NH3 [ADA], Taeniopygia guttata" - xref: Reactome:REACT_96491 "(2'-deoxy)adenosine + H2O => (2'-deoxy)inosine + NH3 [ADA], Xenopus tropicalis" + xref: Reactome:REACT_113447 "(2'-deoxy)adenosine + H2O => (2'-deoxy)inosine + NH3 [ADA], Plasmodium falciparum" + xref: Reactome:REACT_114346 "(2'-deoxy)adenosine + H2O => (2'-deoxy)inosine + NH3 [ADA], Mycobacterium tuberculosis" GO:0004001 : adenosine kinase activity - xref: Reactome:REACT_103469 "(2'-deoxy)adenosine + ATP => (d)AMP + ADP [ADK], Saccharomyces cerevisiae" - xref: Reactome:REACT_107521 "(2'-deoxy)adenosine + ATP => (d)AMP + ADP [ADK], Drosophila melanogaster" - xref: Reactome:REACT_28994 "(2'-deoxy)adenosine + ATP => (d)AMP + ADP [ADK], Sus scrofa" + xref: Reactome:REACT_78906 "(2'-deoxy)adenosine + ATP => (d)AMP + ADP [ADK], Sus scrofa" + xref: Reactome:REACT_112074 "(2'-deoxy)adenosine + ATP => (d)AMP + ADP [ADK], Oryza sativa" + xref: Reactome:REACT_32035 "(2'-deoxy)adenosine + ATP => (d)AMP + ADP [ADK], Saccharomyces cerevisiae" + xref: Reactome:REACT_114269 "(2'-deoxy)adenosine + ATP => (d)AMP + ADP [ADK], Arabidopsis thaliana" GO:0004008 : copper-exporting ATPase activity - synonym: "cu2+-exporting ATPase activity" EXACT [EC:3.6.3.4] GO:0004013 : adenosylhomocysteinase activity - xref: Reactome:REACT_104928 "S-adenoylhomocysteine is hydrolyzed, Saccharomyces cerevisiae" - xref: Reactome:REACT_78422 "S-adenoylhomocysteine is hydrolyzed, Plasmodium falciparum" + xref: Reactome:REACT_77951 "S-adenoylhomocysteine is hydrolyzed, Saccharomyces cerevisiae" GO:0004016 : adenylate cyclase activity - xref: Reactome:REACT_77141 "Production of Cyclic AMP by Activated Adenylyl Cyclase, Bos taurus" - xref: Reactome:REACT_108309 "Adenylate cyclase converts ATP into cyclic AMP, Dictyostelium discoideum" - xref: Reactome:REACT_92888 "Production of Cyclic AMP by Activated Adenylyl Cyclase, Dictyostelium discoideum" - xref: Reactome:REACT_88926 "Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate, Dictyostelium discoideum" - xref: Reactome:REACT_80895 "Activated Adenylate cyclase catalyses cAMP synthesis, Dictyostelium discoideum" + xref: Reactome:REACT_110132 "Production of Cyclic AMP by Activated Adenylyl Cyclase, Bos taurus" + xref: Reactome:REACT_114273 "Production of Cyclic AMP by Activated Adenylyl Cyclase, Xenopus tropicalis" + xref: Reactome:REACT_114694 "Production of Cyclic AMP by Activated Adenylyl Cyclase, Drosophila melanogaster" GO:0004017 : adenylate kinase activity - xref: Reactome:REACT_106045 "ADP + ADP <=> AMP + ATP [AK2], Saccharomyces cerevisiae" - xref: Reactome:REACT_91941 "ADP + ADP <=> AMP + ATP [AK2], Staphylococcus aureus N315" - xref: Reactome:REACT_98422 "ADP + ADP <=> AMP + ATP [AK2], Mycobacterium tuberculosis" - xref: Reactome:REACT_82179 "AMP + ATP <=> ADP + ADP [AK2], Mycobacterium tuberculosis" - xref: Reactome:REACT_80241 "AMP + ATP <=> ADP + ADP [AK2], Saccharomyces cerevisiae" - xref: Reactome:REACT_84293 "AMP + ATP <=> ADP + ADP [AK2], Staphylococcus aureus N315" + xref: Reactome:REACT_106139 "ADP + ADP <=> AMP + ATP [AK2], Saccharomyces cerevisiae" + xref: Reactome:REACT_80849 "AMP + ATP <=> ADP + ADP [AK2], Saccharomyces cerevisiae" + xref: Reactome:REACT_114340 "(d)AMP + ATP <=> (d)ADP + ADP [AK1], Escherichia coli" + xref: Reactome:REACT_114949 "(d)ADP + ADP <=> (d)AMP + ATP [AK1], Escherichia coli" GO:0004018 : N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity - xref: Reactome:REACT_92629 "SAICAR => AICAR + Fumarate, Saccharomyces cerevisiae" + xref: Reactome:REACT_99135 "SAICAR => AICAR + Fumarate, Saccharomyces cerevisiae" GO:0004019 : adenylosuccinate synthase activity - xref: Reactome:REACT_93022 "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS], Saccharomyces cerevisiae" + xref: Reactome:REACT_80422 "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS], Saccharomyces cerevisiae" GO:0004020 : adenylylsulfate kinase activity - xref: Reactome:REACT_77274 "adenylyl sulfate (APS) + ATP => PAPS + ADP, Saccharomyces cerevisiae" - xref: Reactome:REACT_89526 "adenylyl sulfate (APS) + ATP => PAPS + ADP, Schizosaccharomyces pombe" + xref: Reactome:REACT_112719 "adenylyl sulfate (APS) + ATP => PAPS + ADP, Escherichia coli" GO:0004024 : alcohol dehydrogenase activity, zinc-dependent - xref: Reactome:REACT_87603 "ethanol + NAD+ => acetaldehyde + NADH + H+, Drosophila melanogaster" - xref: Reactome:REACT_104324 "ethanol + NAD+ => acetaldehyde + NADH + H+, Caenorhabditis elegans" GO:0004027 : alcohol sulfotransferase activity - xref: Reactome:REACT_111003 "27-hydroxycholesterol + PAPS => 27-hydroxycholesterol 3-sulfate + PAP, Danio rerio" - xref: Reactome:REACT_109667 "cholesterol + PAPS => cholesterol sulfate + PAP, Danio rerio" GO:0004028 : 3-chloroallyl aldehyde dehydrogenase activity - xref: Reactome:REACT_92965 "gamma-butyrobetaine semialdehyde + NAD+ => gamma-butyrobetaine + NADH + H+, Schizosaccharomyces pombe" GO:0004029 : aldehyde dehydrogenase (NAD) activity - xref: Reactome:REACT_103073 "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid, Schizosaccharomyces pombe" - xref: Reactome:REACT_54956 "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial], Schizosaccharomyces pombe" - xref: Reactome:REACT_86640 "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial], Sus scrofa" - xref: Reactome:REACT_91697 "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid, Saccharomyces cerevisiae" - xref: Reactome:REACT_99490 "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic], Saccharomyces cerevisiae" - xref: Reactome:REACT_109613 "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial], Saccharomyces cerevisiae" - xref: Reactome:REACT_57539 "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic], Schizosaccharomyces pombe" + xref: Reactome:REACT_115403 "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic], Dictyostelium discoideum" + xref: Reactome:REACT_114609 "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid, Mycobacterium tuberculosis" + xref: Reactome:REACT_86116 "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial], Sus scrofa" + xref: Reactome:REACT_113214 "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid, Dictyostelium discoideum" + xref: Reactome:REACT_113740 "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic], Mycobacterium tuberculosis" + xref: Reactome:REACT_114032 "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid, Escherichia coli" + xref: Reactome:REACT_112729 "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial], Dictyostelium discoideum" + xref: Reactome:REACT_113173 "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic], Rattus norvegicus" + xref: Reactome:REACT_112808 "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic], Escherichia coli" GO:0004032 : alditol:NADP+ 1-oxidoreductase activity - xref: Reactome:REACT_93254 "Reduction of isocaproaldehyde to 4-methylpentan-1-ol, Schizosaccharomyces pombe" - xref: Reactome:REACT_32685 "Reduction of isocaproaldehyde to 4-methylpentan-1-ol, Escherichia coli" + xref: Reactome:REACT_112358 "Reduction of isocaproaldehyde to 4-methylpentan-1-ol, Dictyostelium discoideum" + xref: Reactome:REACT_114284 "Reduction of isocaproaldehyde to 4-methylpentan-1-ol, Oryza sativa" + xref: Reactome:REACT_112305 "Reduction of isocaproaldehyde to 4-methylpentan-1-ol, Arabidopsis thaliana" GO:0004033 : aldo-keto reductase (NADP) activity - xref: Reactome:REACT_81743 "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one, Sus scrofa" - xref: Reactome:REACT_109253 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol, Escherichia coli" - xref: Reactome:REACT_105354 "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one, Saccharomyces cerevisiae" - xref: Reactome:REACT_105832 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Schizosaccharomyces pombe" - xref: Reactome:REACT_89861 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Bos taurus" - xref: Reactome:REACT_101445 "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol, Bos taurus" - xref: Reactome:REACT_103314 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Escherichia coli" - xref: Reactome:REACT_33558 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one, Saccharomyces cerevisiae" - xref: Reactome:REACT_78718 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol, Sus scrofa" - xref: Reactome:REACT_100788 "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol, Bos taurus" - xref: Reactome:REACT_87218 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Rattus norvegicus" - xref: Reactome:REACT_90965 "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol, Schizosaccharomyces pombe" - xref: Reactome:REACT_94732 "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one, Schizosaccharomyces pombe" - xref: Reactome:REACT_50447 "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one, Schizosaccharomyces pombe" - xref: Reactome:REACT_103049 "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol, Rattus norvegicus" - xref: Reactome:REACT_33921 "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one, Schizosaccharomyces pombe" - xref: Reactome:REACT_82019 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one, Escherichia coli" - xref: Reactome:REACT_84122 "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol, Rattus norvegicus" - xref: Reactome:REACT_106044 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one, Schizosaccharomyces pombe" - xref: Reactome:REACT_91607 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Saccharomyces cerevisiae" - xref: Reactome:REACT_96023 "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one, Escherichia coli" - xref: Reactome:REACT_32624 "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol, Sus scrofa" - xref: Reactome:REACT_31489 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Sus scrofa" - xref: Reactome:REACT_87709 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Saccharomyces cerevisiae" - xref: Reactome:REACT_99652 "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one, Sus scrofa" - xref: Reactome:REACT_102302 "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol, Schizosaccharomyces pombe" - xref: Reactome:REACT_105504 "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one, Sus scrofa" - xref: Reactome:REACT_89542 "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol, Rattus norvegicus" - xref: Reactome:REACT_86091 "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol, Sus scrofa" - xref: Reactome:REACT_103289 "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol, Schizosaccharomyces pombe" - xref: Reactome:REACT_86813 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one, Sus scrofa" - xref: Reactome:REACT_98297 "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one, Escherichia coli" - xref: Reactome:REACT_92432 "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one, Schizosaccharomyces pombe" - xref: Reactome:REACT_34226 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Bos taurus" - xref: Reactome:REACT_108256 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Schizosaccharomyces pombe" - xref: Reactome:REACT_32461 "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one, Schizosaccharomyces pombe" - xref: Reactome:REACT_107571 "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one, Sus scrofa" - xref: Reactome:REACT_81295 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Sus scrofa" - xref: Reactome:REACT_82969 "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol, Sus scrofa" - xref: Reactome:REACT_78223 "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one, Sus scrofa" - xref: Reactome:REACT_97873 "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol, Bos taurus" - xref: Reactome:REACT_80277 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol, Rattus norvegicus" - xref: Reactome:REACT_33883 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol, Schizosaccharomyces pombe" - xref: Reactome:REACT_105012 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol, Bos taurus" - xref: Reactome:REACT_80222 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Rattus norvegicus" - xref: Reactome:REACT_78706 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Escherichia coli" + xref: Reactome:REACT_114670 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one, Arabidopsis thaliana" + xref: Reactome:REACT_114182 "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one, Drosophila melanogaster" + xref: Reactome:REACT_113453 "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one, Oryza sativa" + xref: Reactome:REACT_114951 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol, Dictyostelium discoideum" + xref: Reactome:REACT_85587 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Saccharomyces cerevisiae" + xref: Reactome:REACT_115407 "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one, Arabidopsis thaliana" + xref: Reactome:REACT_114303 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Arabidopsis thaliana" + xref: Reactome:REACT_114413 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Oryza sativa" + xref: Reactome:REACT_113742 "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol, Dictyostelium discoideum" + xref: Reactome:REACT_112164 "Reduction of semidehydroascorbate to ascorbate, Dictyostelium discoideum" + xref: Reactome:REACT_83433 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one, Saccharomyces cerevisiae" + xref: Reactome:REACT_114574 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Dictyostelium discoideum" + xref: Reactome:REACT_112446 "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol, Arabidopsis thaliana" + xref: Reactome:REACT_113482 "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one, Drosophila melanogaster" + xref: Reactome:REACT_112380 "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one, Oryza sativa" + xref: Reactome:REACT_115178 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one, Drosophila melanogaster" + xref: Reactome:REACT_114688 "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol, Drosophila melanogaster" + xref: Reactome:REACT_113982 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Arabidopsis thaliana" + xref: Reactome:REACT_115352 "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one, Arabidopsis thaliana" + xref: Reactome:REACT_113791 "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one, Arabidopsis thaliana" + xref: Reactome:REACT_114529 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol, Drosophila melanogaster" + xref: Reactome:REACT_112136 "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one, Drosophila melanogaster" + xref: Reactome:REACT_112635 "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol, Dictyostelium discoideum" + xref: Reactome:REACT_112538 "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one, Oryza sativa" + xref: Reactome:REACT_113545 "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one, Drosophila melanogaster" + xref: Reactome:REACT_112546 "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol, Arabidopsis thaliana" + xref: Reactome:REACT_113108 "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one, Dictyostelium discoideum" + xref: Reactome:REACT_79323 "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one, Saccharomyces cerevisiae" + xref: Reactome:REACT_114943 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one, Dictyostelium discoideum" + xref: Reactome:REACT_114788 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one, Oryza sativa" + xref: Reactome:REACT_114561 "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol, Oryza sativa" + xref: Reactome:REACT_112352 "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol, Dictyostelium discoideum" + xref: Reactome:REACT_114451 "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol, Oryza sativa" + xref: Reactome:REACT_115369 "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one, Arabidopsis thaliana" + xref: Reactome:REACT_113694 "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one, Drosophila melanogaster" + xref: Reactome:REACT_112477 "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol, Drosophila melanogaster" + xref: Reactome:REACT_113762 "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol, Oryza sativa" + xref: Reactome:REACT_113067 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Dictyostelium discoideum" + xref: Reactome:REACT_112078 "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol, Drosophila melanogaster" + xref: Reactome:REACT_112786 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Drosophila melanogaster" + xref: Reactome:REACT_114601 "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one, Dictyostelium discoideum" + xref: Reactome:REACT_114682 "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one, Oryza sativa" + xref: Reactome:REACT_114934 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol, Oryza sativa" + xref: Reactome:REACT_95886 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Saccharomyces cerevisiae" + xref: Reactome:REACT_113879 "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one, Oryza sativa" + xref: Reactome:REACT_112094 "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one, Dictyostelium discoideum" + xref: Reactome:REACT_113657 "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol, Arabidopsis thaliana" + xref: Reactome:REACT_113590 "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one, Arabidopsis thaliana" + xref: Reactome:REACT_112765 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Oryza sativa" + xref: Reactome:REACT_112004 "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one, Dictyostelium discoideum" + xref: Reactome:REACT_112971 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Drosophila melanogaster" + xref: Reactome:REACT_112547 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol, Arabidopsis thaliana" + xref: Reactome:REACT_111993 "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one, Dictyostelium discoideum" GO:0004051 : arachidonate 5-lipoxygenase activity + xref: Reactome:REACT_115370 "Oxidation of arachidonic acid to 5-HpETE, Dictyostelium discoideum" + xref: Reactome:REACT_113814 "Dehydration of 5-HpETE to leukotriene A4, Dictyostelium discoideum" GO:0004053 : arginase activity - xref: Reactome:REACT_89208 "arginine + H2O => ornithine + urea [ARG1], Bos taurus" + xref: Reactome:REACT_112789 "arginine + H2O => ornithine + urea [ARG1], Caenorhabditis elegans" + xref: Reactome:REACT_99000 "arginine + H2O => ornithine + urea [ARG1], Bos taurus" GO:0004055 : argininosuccinate synthase activity + xref: Reactome:REACT_113640 "ATP + aspartate + citrulline <=> argininosuccinate + AMP + pyrophosphate, Gallus gallus" GO:0004056 : argininosuccinate lyase activity + xref: Reactome:REACT_115252 "argininosuccinate <=> fumarate + arginine, Oryza sativa" + xref: Reactome:REACT_113182 "argininosuccinate <=> fumarate + arginine, Staphylococcus aureus N315" + xref: Reactome:REACT_114192 "argininosuccinate <=> fumarate + arginine, Arabidopsis thaliana" + xref: Reactome:REACT_114884 "argininosuccinate <=> fumarate + arginine, Escherichia coli" GO:0004060 : arylamine N-acetyltransferase activity + xref: Reactome:REACT_115264 "NAT2 acetylation, Staphylococcus aureus N315" + xref: Reactome:REACT_113266 "NAT1 acetylation, Staphylococcus aureus N315" GO:0004062 : aryl sulfotransferase activity - xref: Reactome:REACT_99792 "p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP, Bos taurus" - xref: Reactome:REACT_77257 "Dopamine can form an O-sulfate conjugate, Gallus gallus" - xref: Reactome:REACT_105993 "N-hydroxy-4-aminobiphenyl can form a sulfate conjugate, Gallus gallus" - xref: Reactome:REACT_88015 "Phenol can form a sulfate conjugate, Gallus gallus" - xref: Reactome:REACT_99781 "Acetaminophen can form an O- sulfate conjugate, Gallus gallus" + xref: Reactome:REACT_114894 "N-hydroxy-4-aminobiphenyl can form a sulfate conjugate, Danio rerio" + xref: Reactome:REACT_112861 "p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP, Rattus norvegicus" + xref: Reactome:REACT_114511 "Phenol can form a sulfate conjugate, Danio rerio" + xref: Reactome:REACT_113826 "Acetaminophen can form an O- sulfate conjugate, Danio rerio" + xref: Reactome:REACT_115272 "Dopamine can form an O-sulfate conjugate, Rattus norvegicus" + xref: Reactome:REACT_113420 "Dopamine can form an O-sulfate conjugate, Danio rerio" + xref: Reactome:REACT_113755 "Acetaminophen can form an O- sulfate conjugate, Rattus norvegicus" + xref: Reactome:REACT_104618 "p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP, Bos taurus" + xref: Reactome:REACT_114350 "Phenol can form a sulfate conjugate, Rattus norvegicus" + xref: Reactome:REACT_115246 "N-hydroxy-4-aminobiphenyl can form a sulfate conjugate, Rattus norvegicus" GO:0004066 : asparagine synthase (glutamine-hydrolyzing) activity - xref: Reactome:REACT_29427 "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS], Dictyostelium discoideum" + xref: Reactome:REACT_114769 "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS], Saccharomyces cerevisiae" + xref: Reactome:REACT_113607 "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS], Arabidopsis thaliana" + xref: Reactome:REACT_81036 "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS], Dictyostelium discoideum" + xref: Reactome:REACT_112740 "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS], Oryza sativa" GO:0004069 : L-aspartate:2-oxoglutarate aminotransferase activity - xref: Reactome:REACT_104938 "aspartate + alpha-ketoglutarate <=> oxaloacetate + glutamate [GOT1], Bos taurus" + xref: Reactome:REACT_115018 "aspartate + alpha-ketoglutarate <=> oxaloacetate + glutamate [GOT2], Rattus norvegicus" + xref: Reactome:REACT_113079 "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1], Plasmodium falciparum" + xref: Reactome:REACT_112542 "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2], Plasmodium falciparum" + xref: Reactome:REACT_84706 "aspartate + alpha-ketoglutarate <=> oxaloacetate + glutamate [GOT1], Bos taurus" + xref: Reactome:REACT_115062 "aspartate + alpha-ketoglutarate <=> oxaloacetate + glutamate [GOT2], Plasmodium falciparum" + xref: Reactome:REACT_112410 "aspartate + alpha-ketoglutarate <=> oxaloacetate + glutamate [GOT1], Plasmodium falciparum" + xref: Reactome:REACT_115016 "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2], Rattus norvegicus" GO:0004070 : aspartate carbamoyltransferase activity - xref: Reactome:REACT_33708 "carbamoyl phosphate + L-aspartate <=> N-carbamoyl L-aspartate + orthophosphate, Gallus gallus" - xref: Reactome:REACT_88613 "carbamoyl phosphate + L-aspartate <=> N-carbamoyl L-aspartate + orthophosphate, Xenopus tropicalis" GO:0004084 : branched-chain-amino-acid transaminase activity - xref: Reactome:REACT_81908 "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2], Danio rerio" + xref: Reactome:REACT_112447 "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1], Xenopus tropicalis" GO:0004087 : carbamoyl-phosphate synthase (ammonia) activity + xref: Reactome:REACT_112781 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial], Schizosaccharomyces pombe" + xref: Reactome:REACT_112191 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial], Saccharomyces cerevisiae" + xref: Reactome:REACT_112052 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial], Plasmodium falciparum" GO:0004088 : carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity - xref: Reactome:REACT_95136 "L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate, Xenopus tropicalis" - xref: Reactome:REACT_89022 "L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate, Gallus gallus" GO:0004092 : carnitine O-acetyltransferase activity - xref: Reactome:REACT_81182 "propionyl-CoA + carnitine => propionylcarnitine + CoASH, Drosophila melanogaster" - xref: Reactome:REACT_89111 "acetyl-CoA + carnitine => acetylcarnitine + CoASH, Drosophila melanogaster" - xref: Reactome:REACT_108990 "propionyl-CoA + carnitine => propionylcarnitine + CoASH, Caenorhabditis elegans" - xref: Reactome:REACT_90477 "acetyl-CoA + carnitine => acetylcarnitine + CoASH, Caenorhabditis elegans" GO:0004096 : catalase activity - xref: Reactome:REACT_89257 "2 H2O2 => O2 + 2 H2O, Sus scrofa" - xref: Reactome:REACT_97652 "2 H2O2 => O2 + 2 H2O, Schizosaccharomyces pombe" + xref: Reactome:REACT_112160 "2 H2O2 => O2 + 2 H2O, Caenorhabditis elegans" + xref: Reactome:REACT_89864 "2 H2O2 => O2 + 2 H2O, Sus scrofa" + xref: Reactome:REACT_79757 "2 H2O2 => O2 + 2 H2O, Schizosaccharomyces pombe" GO:0004100 : chitin synthase activity - def: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n) = UDP + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n+1). + def: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n) = UDP + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n+1). GO:0004104 : cholinesterase activity - xref: Reactome:REACT_88765 "Acetylcholine clearance from synaptic cleft, Caenorhabditis elegans" - xref: Reactome:REACT_33172 "Acetylcholine clearance from synaptic cleft, Drosophila melanogaster" GO:0004108 : citrate (Si)-synthase activity - xref: Reactome:REACT_102926 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Saccharomyces cerevisiae" - xref: Reactome:REACT_30454 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Sus scrofa" + xref: Reactome:REACT_96879 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Sus scrofa" GO:0004111 : creatine kinase activity - xref: Reactome:REACT_102773 "creatine + ATP => phosphocreatine + ADP [CK octamer], Sus scrofa" + xref: Reactome:REACT_111938 "creatine + ATP => phosphocreatine + ADP [CKB,CKM], Staphylococcus aureus N315" + xref: Reactome:REACT_34284 "creatine + ATP => phosphocreatine + ADP [CK octamer], Sus scrofa" + xref: Reactome:REACT_112531 "creatine + ATP => phosphocreatine + ADP [CK octamer], Staphylococcus aureus N315" + xref: Reactome:REACT_113875 "creatine + ATP => phosphocreatine + ADP [CK octamer], Rattus norvegicus" GO:0004114 : 3',5'-cyclic-nucleotide phosphodiesterase activity - xref: Reactome:REACT_93497 "Hydrolysis of cAMP to 5' AMP by Phosphorylated PDE3B, Sus scrofa" + xref: Reactome:REACT_82008 "Hydrolysis of cAMP to 5' AMP by Phosphorylated PDE3B, Sus scrofa" + xref: Reactome:REACT_114232 "Hydrolysis of cAMP to 5' AMP by Phosphorylated PDE3B, Plasmodium falciparum" GO:0004115 : 3',5'-cyclic-AMP phosphodiesterase activity - xref: Reactome:REACT_51952 "cAMP degradation by Phosphodiesterases, Plasmodium falciparum" + xref: Reactome:REACT_112238 "cAMP hydrolysis by PDE 4, Dictyostelium discoideum" + xref: Reactome:REACT_115186 "cAMP hydrolysis by PDE 4, Plasmodium falciparum" + xref: Reactome:REACT_77308 "cAMP degradation by Phosphodiesterases, Plasmodium falciparum" GO:0004117 : calmodulin-dependent cyclic-nucleotide phosphodiesterase activity + xref: Reactome:REACT_114485 "cAMP hydrolysis by Cam-PDE 1, Plasmodium falciparum" + xref: Reactome:REACT_114149 "cAMP hydrolysis by Cam-PDE 1, Dictyostelium discoideum" GO:0004128 : cytochrome-b5 reductase activity - xref: Reactome:REACT_91203 "Reduction of ferric cytochrome B5A to ferrous cytochrome B5A, Caenorhabditis elegans" - xref: Reactome:REACT_95013 "Reduction of ferric cytochrome B5A to ferrous cytochrome B5A, Drosophila melanogaster" GO:0004129 : cytochrome-c oxidase activity + xref: Reactome:REACT_115027 "Electron transfer from reduced cytochrome c to molecular oxygen, Rattus norvegicus" + xref: Reactome:REACT_113736 "Electron transfer from reduced cytochrome c to molecular oxygen, Canis familiaris" + xref: Reactome:REACT_113276 "Electron transfer from reduced cytochrome c to molecular oxygen, Bos taurus" + xref: Reactome:REACT_113311 "Electron transfer from reduced cytochrome c to molecular oxygen, Sus scrofa" GO:0004134 : 4-alpha-glucanotransferase activity - def: Catalysis of the transfer of a segment of a (1,4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1,4)-alpha-D-glucan. + def: Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1->4)-alpha-D-glucan. GO:0004135 : amylo-alpha-1,6-glucosidase activity - def: Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the 1,6 glycosidic linkages present. + def: Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the (1->6) glycosidic linkages present. GO:0004140 : dephospho-CoA kinase activity - xref: Reactome:REACT_80050 "Phosphorylation of dephospho-CoA to produce CoA, Mycobacterium tuberculosis" + xref: Reactome:REACT_112662 "Phosphorylation of dephospho-CoA to produce CoA, Plasmodium falciparum" GO:0004143 : diacylglycerol kinase activity - xref: Reactome:REACT_31006 "DAG kinase produces phosphatidic acid from DAG, Dictyostelium discoideum" - xref: Reactome:REACT_100005 "DAG kinase produces phosphatidic acid from DAG, Sus scrofa" + xref: Reactome:REACT_100005 "DAG kinase produces phosphatidic acid from DAG, Sus scrofa > GO:" GO:0004144 : diacylglycerol O-acyltransferase activity - xref: Reactome:REACT_31508 "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2], Sus scrofa" - xref: Reactome:REACT_103954 "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2], Drosophila melanogaster" - xref: Reactome:REACT_94299 "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2], Caenorhabditis elegans" + xref: Reactome:REACT_112715 "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2], Schizosaccharomyces pombe" + xref: Reactome:REACT_114635 "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2], Oryza sativa" + xref: Reactome:REACT_28392 "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2], Sus scrofa" + xref: Reactome:REACT_112540 "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2], Arabidopsis thaliana" GO:0004145 : diamine N-acetyltransferase activity - xref: Reactome:REACT_87724 "Spermine => N-acetylated spermine, Caenorhabditis elegans" + xref: Reactome:REACT_86359 "Spermine => N-acetylated spermine, Caenorhabditis elegans" GO:0004146 : dihydrofolate reductase activity + xref: Reactome:REACT_111041 "Salvage - BH2 is reduced to BH4 by DHFR, Homo sapiens" GO:0004151 : dihydroorotase activity - xref: Reactome:REACT_87197 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Xenopus tropicalis" - xref: Reactome:REACT_77509 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Caenorhabditis elegans" - xref: Reactome:REACT_110467 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Gallus gallus" + xref: Reactome:REACT_33026 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Caenorhabditis elegans" GO:0004157 : dihydropyrimidinase activity - xref: Reactome:REACT_82913 "5,6-dihydrothymine + H2O => beta-ureidoisobutyrate, Caenorhabditis elegans" - xref: Reactome:REACT_94118 "5,6-dihydrouracil + H2O => beta-ureidopropionate, Caenorhabditis elegans" + xref: Reactome:REACT_113000 "5,6-dihydrothymine + H2O => beta-ureidoisobutyrate, Drosophila melanogaster" + xref: Reactome:REACT_113669 "5,6-dihydrouracil + H2O => beta-ureidopropionate, Drosophila melanogaster" GO:0004163 : diphosphomevalonate decarboxylase activity - xref: Reactome:REACT_79689 "Mevalonate-5-pyrophosphate is decarboxylated, Schizosaccharomyces pombe" + xref: Reactome:REACT_33654 "Mevalonate-5-pyrophosphate is decarboxylated, Schizosaccharomyces pombe" GO:0004174 : electron-transferring-flavoprotein dehydrogenase activity - xref: Reactome:REACT_94188 "Transfer of electrons from ETF to ubiquinone by ETF-QO, Sus scrofa" - xref: Reactome:REACT_108818 "Transfer of electrons from ETF to ubiquinone by ETF-QO, Saccharomyces cerevisiae" + xref: Reactome:REACT_32665 "Transfer of electrons from ETF to ubiquinone by ETF-QO, Saccharomyces cerevisiae" + xref: Reactome:REACT_34198 "Transfer of electrons from ETF to ubiquinone by ETF-QO, Sus scrofa" GO:0004175 : endopeptidase activity - xref: Reactome:REACT_110179 "Proteolytic degradation of ubiquitinated-Cdc25A, Dictyostelium discoideum" - xref: Reactome:REACT_102836 "Degradation of multiubiquitinated Cdh1, Arabidopsis thaliana" - xref: Reactome:REACT_91168 "26S proteosome degrades ODC holoenzyme complex, Taeniopygia guttata" - xref: Reactome:REACT_96564 "Proteasome mediated degradation of PAK-2p34, Dictyostelium discoideum" - xref: Reactome:REACT_100671 "Ubiquitinated Cdc6 is degraded by the proteasome, Taeniopygia guttata" - xref: Reactome:REACT_94246 "APC/C:Cdh1-mediated degradation of Skp2, Taeniopygia guttata" - xref: Reactome:REACT_104484 "Degradation of multiubiquitinated Cdh1, Taeniopygia guttata" - xref: Reactome:REACT_97698 "Degradation of multiubiquitinated cell cycle proteins, Arabidopsis thaliana" - xref: Reactome:REACT_87600 "Proteasome mediated degradation of PAK-2p34, Caenorhabditis elegans" - xref: Reactome:REACT_91983 "Ubiquitinated Orc1 is degraded by the proteasome, Arabidopsis thaliana" - xref: Reactome:REACT_104263 "Proteasome mediated degradation of COP1, Taeniopygia guttata" - xref: Reactome:REACT_77036 "Degradation of multiubiquitinated Securin, Taeniopygia guttata" - xref: Reactome:REACT_89575 "Degradation of multiubiquitinated Securin, Arabidopsis thaliana" - xref: Reactome:REACT_33799 "Proteasome mediated degradation of Cyclin D1, Taeniopygia guttata" - xref: Reactome:REACT_97537 "SCF-mediated degradation of Emi1, Schizosaccharomyces pombe" - xref: Reactome:REACT_88805 "Ubiquitinated Orc1 is degraded by the proteasome, Saccharomyces cerevisiae" - xref: Reactome:REACT_90352 "Proteasome mediated degradation of PAK-2p34, Schizosaccharomyces pombe" - xref: Reactome:REACT_78474 "Degradation of multiubiquitinated cell cycle proteins, Taeniopygia guttata" - xref: Reactome:REACT_32577 "Degradation multiubiquitinated Cyclin A, Taeniopygia guttata" - xref: Reactome:REACT_94571 "Ubiquitinated Orc1 is degraded by the proteasome, Schizosaccharomyces pombe" - xref: Reactome:REACT_106215 "Ubiquitinated Orc1 is degraded by the proteasome, Taeniopygia guttata" - xref: Reactome:REACT_105110 "Ubiquitinated geminin is degraded by the proteasome, Taeniopygia guttata" - xref: Reactome:REACT_102595 "Proteasome mediated degradation of PAK-2p34, Taeniopygia guttata" - xref: Reactome:REACT_101545 "Degradation of ubiquitinated -beta catenin by the proteasome, Taeniopygia guttata" - xref: Reactome:REACT_28760 "Ubiquitinated Cdc6 is degraded by the proteasome, Schizosaccharomyces pombe" - xref: Reactome:REACT_38654 "Ubiquitinated Cdc6 is degraded by the proteasome, Caenorhabditis elegans" - xref: Reactome:REACT_28162 "Ubiquitinated Cdc6 is degraded by the proteasome, Saccharomyces cerevisiae" - xref: Reactome:REACT_110886 "SCF-mediated degradation of Emi1, Taeniopygia guttata" - xref: Reactome:REACT_92274 "Proteasome mediated degradation of PAK-2p34, Saccharomyces cerevisiae" - xref: Reactome:REACT_95706 "SCF-mediated degradation of Emi1, Caenorhabditis elegans" - xref: Reactome:REACT_95228 "Proteolytic degradation of ubiquitinated-Cdc25A, Taeniopygia guttata" - xref: Reactome:REACT_102304 "Proteasome mediated degradation of COP1, Arabidopsis thaliana" - xref: Reactome:REACT_109046 "SCF-mediated degradation of Emi1, Bos taurus" - xref: Reactome:REACT_85553 "Ubiquitinated Cdc6 is degraded by the proteasome, Arabidopsis thaliana" - xref: Reactome:REACT_81430 "APC/C:Cdh1-mediated degradation of Skp2, Arabidopsis thaliana" + xref: Reactome:REACT_115363 "Proteasome mediated degradation of Cyclin D1, Oryza sativa" + xref: Reactome:REACT_114002 "Proteasome mediated degradation of PAK-2p34, Sus scrofa" + xref: Reactome:REACT_114993 "Proteasome mediated degradation of COP1, Sus scrofa" + xref: Reactome:REACT_113749 "Ubiquitinated Orc1 is degraded by the proteasome, Sus scrofa" + xref: Reactome:REACT_114449 "Proteasome mediated degradation of Cyclin D1, Sus scrofa" + xref: Reactome:REACT_106687 "SCF-mediated degradation of Emi1, Bos taurus" + xref: Reactome:REACT_111172 "Proteasomal clevage of exogenous antigen, Homo sapiens" + xref: Reactome:REACT_112076 "Ubiquitinated Cdc6 is degraded by the proteasome, Sus scrofa" + xref: Reactome:REACT_113623 "Ubiquitinated geminin is degraded by the proteasome, Sus scrofa" + xref: Reactome:REACT_111104 "Proteasomal cleavage of substrate, Homo sapiens" + xref: Reactome:REACT_111098 "Processing of SCF isoform 1, Homo sapiens" GO:0004177 : aminopeptidase activity + xref: Reactome:REACT_111222 "Trimming of peptides by IRAP in endocytic vesicles, Homo sapiens" GO:0004190 : aspartic-type endopeptidase activity - xref: Reactome:REACT_105745 "NEXT4 is cleaved to produce NICD4, Sus scrofa" - xref: Reactome:REACT_95986 "NEXT2 is cleaved to produce NICD2, Sus scrofa" - xref: Reactome:REACT_100023 "NEXT2 is cleaved to produce NICD2, Taeniopygia guttata" + xref: Reactome:REACT_93980 "NEXT2 is cleaved to produce NICD2, Sus scrofa" + xref: Reactome:REACT_29012 "NEXT4 is cleaved to produce NICD4, Sus scrofa" + xref: Reactome:REACT_114839 "NEXT4 is cleaved to produce NICD4, Xenopus tropicalis" + xref: Reactome:REACT_114927 "NEXT3 is cleaved to produce NICD3, Drosophila melanogaster" GO:0004197 : cysteine-type endopeptidase activity - xref: Reactome:REACT_33402 "Caspase-mediated cleavage of E-Cadherin, Xenopus tropicalis" - xref: Reactome:REACT_79807 "Caspase-mediated cleavage of gelsolin, Xenopus tropicalis" - xref: Reactome:REACT_78903 "Caspase-mediated cleavage of gelsolin, Taeniopygia guttata" - xref: Reactome:REACT_110981 "Caspase-mediated cleavage of claspin, Sus scrofa" + xref: Reactome:REACT_112287 "Activation of caspase-3, Xenopus tropicalis" + xref: Reactome:REACT_112426 "Caspase-mediated cleavage of Desmoglein 1, Xenopus tropicalis" + xref: Reactome:REACT_112363 "Cleavage of Procaspase-9 to Caspase-9, Sus scrofa" + xref: Reactome:REACT_115318 "Caspase-mediated cleavage of plectin-1, Taeniopygia guttata" + xref: Reactome:REACT_111140 "Antigen processing by cathepsin S in endosoytic vesicle, Homo sapiens" + xref: Reactome:REACT_112597 "Caspase-mediated cleavage of Desmoglein 3, Xenopus tropicalis" + xref: Reactome:REACT_112407 "Caspase mediated cleavage of vimentin at IDVD (259), Caenorhabditis elegans" + xref: Reactome:REACT_113941 "Cleavage of Procaspase-3 by the apoptosome, Sus scrofa" + xref: Reactome:REACT_114872 "Caspase mediated cleavage of BAP31, Caenorhabditis elegans" + xref: Reactome:REACT_114638 "Caspase-mediated cleavage of Acinus, Xenopus tropicalis" + xref: Reactome:REACT_115070 "Caspase-mediated cleavage of Rock-1, Canis familiaris" + xref: Reactome:REACT_114579 "Cleavage of Procaspase-9 to Caspase-9, Rattus norvegicus" + xref: Reactome:REACT_91694 "Caspase-mediated cleavage of claspin, Sus scrofa" + xref: Reactome:REACT_114270 "Caspase mediated cleavage of alpha-II-Fodrin, Xenopus tropicalis" + xref: Reactome:REACT_115257 "Cleavage of Procaspase-3 by the apoptosome, Rattus norvegicus" + xref: Reactome:REACT_113588 "Caspase-mediated cleavage of Desmoglein 2, Xenopus tropicalis" + xref: Reactome:REACT_111954 "Cleavage of Procaspase-7 by the apoptosome, Rattus norvegicus" + xref: Reactome:REACT_114571 "Cleavage of Procaspase-7 by the apoptosome, Bos taurus" + xref: Reactome:REACT_114354 "Cleavage of Procaspase-3 by the apoptosome, Bos taurus" + xref: Reactome:REACT_112859 "Cleavage of Procaspase-7 by the apoptosome, Canis familiaris" + xref: Reactome:REACT_112616 "Cleavage of Procaspase-7 by the apoptosome, Sus scrofa" + xref: Reactome:REACT_113277 "Cleavage of Procaspase-3 by the apoptosome, Canis familiaris" + xref: Reactome:REACT_115379 "Cleavage of Procaspase-9 to Caspase-9, Bos taurus" + xref: Reactome:REACT_113141 "Cleavage of Procaspase-9 to Caspase-9, Canis familiaris" GO:0004219 : pyroglutamyl-peptidase I activity - synonym: "pyrase activity" EXACT [EC:3.4.19.3] GO:0004222 : metalloendopeptidase activity - xref: Reactome:REACT_90189 "Proteolysis of the IGF:IGFBP-5:ALS Complex by PAPP-A2, Bos taurus" - xref: Reactome:REACT_86614 "Proteolysis of the IGF:IGFBP-3:ALS Complex by Matrix Metalloproteinase, Bos taurus" - xref: Reactome:REACT_110874 "Proteolysis of the IGF:IGFBP-4 Complex by PAPP-A, Bos taurus" + xref: Reactome:REACT_102187 "Proteolysis of the IGF:IGFBP-4 Complex by PAPP-A, Bos taurus" + xref: Reactome:REACT_30876 "Proteolysis of the IGF:IGFBP-5:ALS Complex by PAPP-A2, Bos taurus" + xref: Reactome:REACT_111197 "Metalloprotease cleavage of GHR, Homo sapiens" + xref: Reactome:REACT_111084 "ADAM17 cleavage of Ghr, Mus musculus" + xref: Reactome:REACT_32065 "Proteolysis of the IGF:IGFBP-3:ALS Complex by Matrix Metalloproteinase, Bos taurus" GO:0004252 : serine-type endopeptidase activity - xref: Reactome:REACT_98547 "Activation of C1R, Danio rerio" - xref: Reactome:REACT_32038 "crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin, Sus scrofa" - xref: Reactome:REACT_79717 "Processing of classical PDGFs, Drosophila melanogaster" - xref: Reactome:REACT_33163 "Cleavage of C3 by C3 convertases, Xenopus tropicalis" - xref: Reactome:REACT_84855 "Activation of C1S, Gallus gallus" - xref: Reactome:REACT_98087 "plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [one-chain] catalyst), Sus scrofa" - xref: Reactome:REACT_101759 "plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [two-chain] catalyst), Sus scrofa" - xref: Reactome:REACT_83945 "Processing of classical PDGFs, Caenorhabditis elegans" - xref: Reactome:REACT_34485 "Proteolysis of the IGF:IGFBP-3:ALS Complex by Plasmin, Bos taurus" - xref: Reactome:REACT_107130 "Activation of C1S, Danio rerio" - xref: Reactome:REACT_78068 "protein C -> activated protein C + protein C heavy chain activation peptide, Danio rerio" - xref: Reactome:REACT_83024 "Activation of C1S, Canis familiaris" - xref: Reactome:REACT_84935 "Conversion of C2 into C2a and C2b, Xenopus tropicalis" - xref: Reactome:REACT_97222 "pro-prothrombin -> prothrombin + prothrombin propeptide, Sus scrofa" - xref: Reactome:REACT_93727 "pro-factor IX -> factor IX + factor IX propeptide, Sus scrofa" - xref: Reactome:REACT_91922 "Conversion of C2 into C2a and C2b, Danio rerio" - xref: Reactome:REACT_83288 "urokinase plasminogen activator (one-chain):uPAR -> urokinase plasminogen activator (two-chain):uPAR, Sus scrofa" - xref: Reactome:REACT_29374 "Conversion of C4 into C4a and C4b, Danio rerio" - xref: Reactome:REACT_93607 "Activation of C1R, Gallus gallus" - xref: Reactome:REACT_92283 "Activation of C1S, Taeniopygia guttata" - xref: Reactome:REACT_33696 "Proteolysis of the IGF:IGFBP-3:ALS Complex by Cathepsin G, Bos taurus" - xref: Reactome:REACT_78443 "Notch 2 precursor cleaved to form a heterodimer, Taeniopygia guttata" - xref: Reactome:REACT_90529 "pro-protein S -> protein S + protein S propeptide, Sus scrofa" - xref: Reactome:REACT_96691 "Activation of C1R, Taeniopygia guttata" - xref: Reactome:REACT_93023 "Activation of C1R, Canis familiaris" - xref: Reactome:REACT_104427 "pro-factor X -> factor X + factor X propeptide, Sus scrofa" - xref: Reactome:REACT_31776 "Proteolysis of the IGF:IGFBP-3:ALS Complex by Thrombin, Bos taurus" - xref: Reactome:REACT_82757 "crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin, Sus scrofa" - xref: Reactome:REACT_105217 "crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain), Sus scrofa" - xref: Reactome:REACT_108422 "Activation of C5, Xenopus tropicalis" + xref: Reactome:REACT_113831 "crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain), Xenopus tropicalis" + xref: Reactome:REACT_114147 "factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer, Mus musculus" + xref: Reactome:REACT_112253 "factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides, Danio rerio" + xref: Reactome:REACT_107456 "plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [two-chain] catalyst), Sus scrofa" + xref: Reactome:REACT_112143 "factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst), Bos taurus" + xref: Reactome:REACT_104930 "pro-factor IX -> factor IX + factor IX propeptide, Sus scrofa" + xref: Reactome:REACT_115078 "factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer, Danio rerio" + xref: Reactome:REACT_97801 "crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin, Sus scrofa" + xref: Reactome:REACT_115043 "Latent TGF-beta1 is cleaved by furin, Drosophila melanogaster" + xref: Reactome:REACT_112184 "crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin, Xenopus tropicalis" + xref: Reactome:REACT_114347 "factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides, Xenopus tropicalis" + xref: Reactome:REACT_112453 "Notch 3 precursor cleaved to form a heterodimer, Drosophila melanogaster" + xref: Reactome:REACT_111228 "Cleavage of NODAL Proprotein, Homo sapiens" + xref: Reactome:REACT_112800 "Latent TGF-beta1 is cleaved by furin, Caenorhabditis elegans" + xref: Reactome:REACT_113760 "factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst), Sus scrofa" + xref: Reactome:REACT_114464 "crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin, Xenopus tropicalis" + xref: Reactome:REACT_112572 "Cleavage of the Signal Peptide of Preproinsulin, Gallus gallus" + xref: Reactome:REACT_114209 "factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer, Canis familiaris" + xref: Reactome:REACT_115086 "factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer, Taeniopygia guttata" + xref: Reactome:REACT_112763 "Notch 4 precursor cleaved to form a heterodimer, Xenopus tropicalis" + xref: Reactome:REACT_112440 "factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst), Xenopus tropicalis" + xref: Reactome:REACT_92110 "plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [one-chain] catalyst), Sus scrofa" + xref: Reactome:REACT_113002 "factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst), Rattus norvegicus" + xref: Reactome:REACT_112058 "factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst), Xenopus tropicalis" + xref: Reactome:REACT_112843 "factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst), Xenopus tropicalis" + xref: Reactome:REACT_112131 "factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst), Gallus gallus" + xref: Reactome:REACT_84305 "pro-factor X -> factor X + factor X propeptide, Sus scrofa" + xref: Reactome:REACT_112675 "factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer, Xenopus tropicalis" + xref: Reactome:REACT_115338 "protein C -> activated protein C + protein C heavy chain activation peptide, Xenopus tropicalis" + xref: Reactome:REACT_107946 "pro-protein S -> protein S + protein S propeptide, Sus scrofa" + xref: Reactome:REACT_78477 "crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain), Sus scrofa" + xref: Reactome:REACT_112194 "factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst), Danio rerio" + xref: Reactome:REACT_83770 "Proteolysis of the IGF:IGFBP-3:ALS Complex by Cathepsin G, Bos taurus" + xref: Reactome:REACT_115256 "factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst), Mus musculus" + xref: Reactome:REACT_113539 "factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst), Taeniopygia guttata" + xref: Reactome:REACT_114654 "Cleavage of the Signal Peptide of Preproinsulin, Rattus norvegicus" + xref: Reactome:REACT_112489 "factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer, Bos taurus" + xref: Reactome:REACT_102247 "urokinase plasminogen activator (one-chain):uPAR -> urokinase plasminogen activator (two-chain):uPAR, Sus scrofa" + xref: Reactome:REACT_111180 "Cleavage of Nodal Proprotein, Mus musculus" + xref: Reactome:REACT_89476 "Proteolysis of the IGF:IGFBP-3:ALS Complex by Plasmin, Bos taurus" + xref: Reactome:REACT_112510 "factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer, Rattus norvegicus" + xref: Reactome:REACT_113239 "factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer, Gallus gallus" + xref: Reactome:REACT_113596 "factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst), Xenopus tropicalis" + xref: Reactome:REACT_79426 "crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin, Sus scrofa" + xref: Reactome:REACT_112277 "Granzyme-B activates BID by cleavage, Xenopus tropicalis" + xref: Reactome:REACT_114057 "fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B, Sus scrofa" + xref: Reactome:REACT_112204 "factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer, Sus scrofa" + xref: Reactome:REACT_28152 "pro-prothrombin -> prothrombin + prothrombin propeptide, Sus scrofa" + xref: Reactome:REACT_112053 "factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst), Canis familiaris" + xref: Reactome:REACT_89358 "Proteolysis of the IGF:IGFBP-3:ALS Complex by Thrombin, Bos taurus" GO:0004300 : enoyl-CoA hydratase activity - xref: Reactome:REACT_77517 "trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA, Escherichia coli" - xref: Reactome:REACT_34688 "trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA, Escherichia coli" - xref: Reactome:REACT_51199 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Bos taurus" + xref: Reactome:REACT_99776 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Bos taurus" GO:0004304 : estrone sulfotransferase activity + xref: Reactome:REACT_113027 "estrone + PAPS => estrone 3-sulfate + PAP, Gallus gallus" GO:0004310 : farnesyl-diphosphate farnesyltransferase activity + xref: Reactome:REACT_112589 "Two FPP molecules dimerize to form presqualene diphosphate, Xenopus tropicalis" + xref: Reactome:REACT_112901 "Reduction of presqualene diphosphate to form squalene, Xenopus tropicalis" GO:0004312 : fatty acid synthase activity + xref: Reactome:REACT_112198 "acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O, Mycobacterium tuberculosis" + xref: Reactome:REACT_113128 "acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O, Dictyostelium discoideum" GO:0004325 : ferrochelatase activity - xref: Reactome:REACT_98040 "Ferrous iron is inserted into protoporphyrin IX to form heme, Saccharomyces cerevisiae" - xref: Reactome:REACT_31452 "Ferrous iron is inserted into protoporphyrin IX to form heme, Schizosaccharomyces pombe" - xref: Reactome:REACT_86629 "Ferrous iron is inserted into protoporphyrin IX to form heme, Dictyostelium discoideum" + xref: Reactome:REACT_113497 "Ferrous iron is inserted into protoporphyrin IX to form heme, Oryza sativa" + xref: Reactome:REACT_96094 "Ferrous iron is inserted into protoporphyrin IX to form heme, Saccharomyces cerevisiae" + xref: Reactome:REACT_115167 "Ferrous iron is inserted into protoporphyrin IX to form heme, Arabidopsis thaliana" + xref: Reactome:REACT_78000 "Ferrous iron is inserted into protoporphyrin IX to form heme, Dictyostelium discoideum" + xref: Reactome:REACT_102151 "Ferrous iron is inserted into protoporphyrin IX to form heme, Schizosaccharomyces pombe" GO:0004326 : tetrahydrofolylpolyglutamate synthase activity - xref: Reactome:REACT_93958 "Conversion of mitochondrial THF to THF-polyglutamate, Bos taurus" - xref: Reactome:REACT_97478 "Conversion of mitochondrial THF to THF-polyglutamate, Sus scrofa" - xref: Reactome:REACT_110751 "Conversion of cytosolic THF to THF-polyglutamate, Caenorhabditis elegans" - xref: Reactome:REACT_107948 "Conversion of cytosolic THF to THF-polyglutamate, Schizosaccharomyces pombe" + xref: Reactome:REACT_109341 "Conversion of cytosolic THF to THF-polyglutamate, Schizosaccharomyces pombe" + xref: Reactome:REACT_104661 "Conversion of cytosolic THF to THF-polyglutamate, Caenorhabditis elegans" + xref: Reactome:REACT_83339 "Conversion of mitochondrial THF to THF-polyglutamate, Sus scrofa" + xref: Reactome:REACT_78566 "Conversion of mitochondrial THF to THF-polyglutamate, Bos taurus" GO:0004329 : formate-tetrahydrofolate ligase activity - xref: Reactome:REACT_33725 "THF polyglutamate + formate + ATP => 10-formylTHF polyglutamate + ADP + orthophosphate, Dictyostelium discoideum" - xref: Reactome:REACT_101809 "THF polyglutamate + formate + ATP => 10-formylTHF polyglutamate + ADP + orthophosphate, Arabidopsis thaliana" - xref: Reactome:REACT_28707 "THF polyglutamate + formate + ATP => 10-formylTHF polyglutamate + ADP + orthophosphate, Escherichia coli" - xref: Reactome:REACT_82353 "THF polyglutamate + formate + ATP => 10-formylTHF polyglutamate + ADP + orthophosphate, Sus scrofa" - xref: Reactome:REACT_89786 "THF polyglutamate + formate + ATP => 10-formylTHF polyglutamate + ADP + orthophosphate, Staphylococcus aureus N315" - xref: Reactome:REACT_91991 "THF polyglutamate + formate + ATP => 10-formylTHF polyglutamate + ADP + orthophosphate, Caenorhabditis elegans" - xref: Reactome:REACT_33036 "THF polyglutamate + formate + ATP => 10-formylTHF polyglutamate + ADP + orthophosphate, Oryza sativa" + xref: Reactome:REACT_84185 "THF polyglutamate + formate + ATP => 10-formylTHF polyglutamate + ADP + orthophosphate, Sus scrofa" + xref: Reactome:REACT_112991 "THF polyglutamate + formate + ATP => 10-formylTHF polyglutamate + ADP + orthophosphate, Xenopus tropicalis" GO:0004331 : fructose-2,6-bisphosphate 2-phosphatase activity - xref: Reactome:REACT_34437 "Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate, Saccharomyces cerevisiae" + xref: Reactome:REACT_102107 "Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate, Saccharomyces cerevisiae" + xref: Reactome:REACT_113676 "Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate, Gallus gallus" GO:0004332 : fructose-bisphosphate aldolase activity - xref: Reactome:REACT_80137 "dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate <=> D-fructose 1,6-bisphosphate, Plasmodium falciparum" - xref: Reactome:REACT_32660 "D-fructose 1-phosphate <=> D-glyceraldehyde + dihydroxyacetone phosphate, Dictyostelium discoideum" + xref: Reactome:REACT_88447 "dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate <=> D-fructose 1,6-bisphosphate, Plasmodium falciparum" + xref: Reactome:REACT_80109 "D-fructose 1-phosphate <=> D-glyceraldehyde + dihydroxyacetone phosphate, Dictyostelium discoideum" GO:0004333 : fumarate hydratase activity + xref: Reactome:REACT_115295 "Fumarate + H2O <=> (S)-Malate, Xenopus tropicalis" GO:0004334 : fumarylacetoacetase activity - xref: Reactome:REACT_108367 "fumarylacetoacetate => fumarate + acetoacetate, Sus scrofa" + xref: Reactome:REACT_105315 "fumarylacetoacetate => fumarate + acetoacetate, Sus scrofa" GO:0004335 : galactokinase activity + xref: Reactome:REACT_113809 "ATP + D-galactose => ADP + D-galactose 1-phosphate, Mycobacterium tuberculosis" GO:0004336 : galactosylceramidase activity - synonym: "galactosylceramide.beta-galactosidase activity" EXACT [EC:3.2.1.46] - synonym: "galactocerebroside.beta-galactosidase activity" EXACT [EC:3.2.1.46] GO:0004338 : glucan exo-1,3-beta-glucosidase activity - def: Catalysis of the successive hydrolysis of beta-D-glucose units from the non-reducing ends of 1,3-beta-D-glucans, releasing alpha-glucose. + def: Catalysis of the successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose. GO:0004339 : glucan 1,4-alpha-glucosidase activity - def: Catalysis of the hydrolysis of terminal 1,4-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose. + def: Catalysis of the hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose. GO:0004340 : glucokinase activity - xref: Reactome:REACT_81299 "alpha-D-Glucose + ATP => alpha-D-glucose 6-phosphate + ADP, Sus scrofa" - xref: Reactome:REACT_96972 "alpha-D-Glucose + ATP => alpha-D-glucose 6-phosphate + ADP, Saccharomyces cerevisiae" - xref: Reactome:REACT_31874 "alpha-D-Glucose + ATP => alpha-D-glucose 6-phosphate + ADP, Drosophila melanogaster" + xref: Reactome:REACT_90073 "alpha-D-Glucose + ATP => alpha-D-glucose 6-phosphate + ADP, Saccharomyces cerevisiae" + xref: Reactome:REACT_109618 "alpha-D-Glucose + ATP => alpha-D-glucose 6-phosphate + ADP, Sus scrofa" GO:0004345 : glucose-6-phosphate dehydrogenase activity + xref: Reactome:REACT_112685 "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+, Plasmodium falciparum" + xref: Reactome:REACT_114196 "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+, Xenopus tropicalis" + xref: Reactome:REACT_114740 "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+, Dictyostelium discoideum" GO:0004347 : glucose-6-phosphate isomerase activity - xref: Reactome:REACT_107487 "D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate, Schizosaccharomyces pombe" + xref: Reactome:REACT_115143 "D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate, Arabidopsis thaliana" + xref: Reactome:REACT_103273 "D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate, Schizosaccharomyces pombe" + xref: Reactome:REACT_113483 "alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate, Arabidopsis thaliana" GO:0004353 : glutamate dehydrogenase [NAD(P)+] activity - xref: Reactome:REACT_82949 "alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1], Bos taurus" - xref: Reactome:REACT_81956 "alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1], Sus scrofa" - xref: Reactome:REACT_97307 "glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1], Sus scrofa" - xref: Reactome:REACT_90311 "glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1], Bos taurus" - xref: Reactome:REACT_88656 "alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1], Rattus norvegicus" - xref: Reactome:REACT_97135 "glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1], Rattus norvegicus" + xref: Reactome:REACT_112437 "alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1], Canis familiaris" + xref: Reactome:REACT_113249 "glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1], Staphylococcus aureus N315" + xref: Reactome:REACT_112733 "alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1], Staphylococcus aureus N315" + xref: Reactome:REACT_114470 "glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1], Canis familiaris" GO:0004356 : glutamate-ammonia ligase activity + xref: Reactome:REACT_115035 "glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL], Arabidopsis thaliana" + xref: Reactome:REACT_112105 "glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL], Oryza sativa" GO:0004359 : glutaminase activity - xref: Reactome:REACT_77355 "glutamine + H2O => glutamate + NH4+ [GLS], Bos taurus" + xref: Reactome:REACT_108874 "glutamine + H2O => glutamate + NH4+ [GLS], Bos taurus" GO:0004361 : glutaryl-CoA dehydrogenase activity - xref: Reactome:REACT_106441 "glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2, Sus scrofa" + xref: Reactome:REACT_110967 "glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2, Sus scrofa" GO:0004362 : glutathione-disulfide reductase activity - xref: Reactome:REACT_96541 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+, Oryza sativa" - xref: Reactome:REACT_101227 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+, Arabidopsis thaliana" GO:0004363 : glutathione synthase activity - xref: Reactome:REACT_100506 "gamma-glutamylcysteine combines with glycine to form glutathione, Saccharomyces cerevisiae" + xref: Reactome:REACT_104397 "gamma-glutamylcysteine combines with glycine to form glutathione, Saccharomyces cerevisiae" GO:0004364 : glutathione transferase activity + xref: Reactome:REACT_114178 "Glutathione conjugation of luminal substrates, Plasmodium falciparum" + xref: Reactome:REACT_114776 "Glutathione conjugation of cytosolic substrates, Plasmodium falciparum" + xref: Reactome:REACT_114437 "Glutathione conjugation of cytosolic substrates, Arabidopsis thaliana" + xref: Reactome:REACT_113981 "Glutathione conjugation of cytosolic substrates, Oryza sativa" GO:0004365 : glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity - xref: Reactome:REACT_78137 "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+, Caenorhabditis elegans" - xref: Reactome:REACT_98912 "D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+, Dictyostelium discoideum" + xref: Reactome:REACT_112334 "D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+, Oryza sativa" + xref: Reactome:REACT_115033 "D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+, Xenopus tropicalis" + xref: Reactome:REACT_32485 "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+, Caenorhabditis elegans" + xref: Reactome:REACT_115268 "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+, Oryza sativa" + xref: Reactome:REACT_115436 "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+, Arabidopsis thaliana" + xref: Reactome:REACT_112690 "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+, Drosophila melanogaster" + xref: Reactome:REACT_114520 "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+, Plasmodium falciparum" + xref: Reactome:REACT_80434 "D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+, Dictyostelium discoideum" + xref: Reactome:REACT_113461 "D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+, Drosophila melanogaster" + xref: Reactome:REACT_113850 "D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+, Plasmodium falciparum" + xref: Reactome:REACT_112805 "D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+, Arabidopsis thaliana" + xref: Reactome:REACT_113644 "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+, Xenopus tropicalis" GO:0004366 : glycerol-3-phosphate O-acyltransferase activity - xref: Reactome:REACT_34083 "glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [ER membrane-associated], Sus scrofa" + xref: Reactome:REACT_32967 "glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [ER membrane-associated], Sus scrofa" + xref: Reactome:REACT_114724 "glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [ER membrane-associated], Dictyostelium discoideum" + xref: Reactome:REACT_113073 "glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated], Mycobacterium tuberculosis" + xref: Reactome:REACT_112568 "glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated], Escherichia coli" + xref: Reactome:REACT_114086 "glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [ER membrane-associated], Arabidopsis thaliana" GO:0004367 : glycerol-3-phosphate dehydrogenase [NAD+] activity - xref: Reactome:REACT_33567 "Conversion of Dihydroxyacetone Phosphate to Glycerol -3- phosphate, Oryza sativa" - xref: Reactome:REACT_96383 "Conversion of Dihydroxyacetone Phosphate to Glycerol -3- phosphate, Arabidopsis thaliana" - xref: Reactome:REACT_79099 "Conversion of Dihydroxyacetone Phosphate to Glycerol -3- phosphate, Drosophila melanogaster" + xref: Reactome:REACT_115427 "Conversion of Dihydroxyacetone Phosphate to Glycerol -3- phosphate, Caenorhabditis elegans" + xref: Reactome:REACT_113156 "Conversion of Dihydroxyacetone Phosphate to Glycerol -3- phosphate, Danio rerio" GO:0004368 : glycerol-3-phosphate dehydrogenase activity - xref: Reactome:REACT_107630 "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase), Schizosaccharomyces pombe" - xref: Reactome:REACT_77366 "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase), Saccharomyces cerevisiae" + xref: Reactome:REACT_77515 "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase), Schizosaccharomyces pombe" + xref: Reactome:REACT_115394 "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase), Drosophila melanogaster" + xref: Reactome:REACT_112809 "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase), Mycobacterium tuberculosis" + xref: Reactome:REACT_114651 "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase), Caenorhabditis elegans" + xref: Reactome:REACT_104083 "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase), Saccharomyces cerevisiae" GO:0004372 : glycine hydroxymethyltransferase activity - xref: Reactome:REACT_79534 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Caenorhabditis elegans" - xref: Reactome:REACT_34625 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Saccharomyces cerevisiae" + xref: Reactome:REACT_115121 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Mycobacterium tuberculosis" + xref: Reactome:REACT_114576 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Mycobacterium tuberculosis" + xref: Reactome:REACT_110497 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Saccharomyces cerevisiae" + xref: Reactome:REACT_91776 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Caenorhabditis elegans" + xref: Reactome:REACT_114244 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Escherichia coli" + xref: Reactome:REACT_114305 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Staphylococcus aureus N315" + xref: Reactome:REACT_114385 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Staphylococcus aureus N315" + xref: Reactome:REACT_113302 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Escherichia coli" + xref: Reactome:REACT_112625 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Mycobacterium tuberculosis" + xref: Reactome:REACT_112714 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Staphylococcus aureus N315" + xref: Reactome:REACT_113467 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Escherichia coli" GO:0004373 : glycogen (starch) synthase activity - xref: Reactome:REACT_89752 "8 UDP-glucose + ((1,4)-alpha-D-glucosyl)4 glycogenin => 8 UDP + ((1,4)-alpha-D-glucosyl)8 glycogenin [GYS D form], Bos taurus" + xref: Reactome:REACT_101890 "8 UDP-glucose + ((1,4)-alpha-D-glucosyl)4 glycogenin => 8 UDP + ((1,4)-alpha-D-glucosyl)8 glycogenin [GYS D form], Bos taurus" GO:0004376 : glycolipid mannosyltransferase activity - xref: Reactome:REACT_100815 "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate, Saccharomyces cerevisiae" - xref: Reactome:REACT_77543 "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate, Sus scrofa" - xref: Reactome:REACT_29714 "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate, Saccharomyces cerevisiae" - xref: Reactome:REACT_90925 "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate, Sus scrofa" + xref: Reactome:REACT_89761 "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate, Saccharomyces cerevisiae" + xref: Reactome:REACT_111941 "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate, Xenopus tropicalis" + xref: Reactome:REACT_101404 "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate, Saccharomyces cerevisiae" + xref: Reactome:REACT_78994 "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate, Sus scrofa" + xref: Reactome:REACT_78709 "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate, Sus scrofa" GO:0004377 : GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity - name: glycolipid 2-alpha-mannosyltransferase activity + name: GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity - def: Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-1,2-D-mannosyl-D-mannose linkage. + def: Catalysis of the reaction: an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP + 2 H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage. + synonym: "glycolipid 2-alpha-mannosyltransferase activity" EXACT [EC:2.4.1.131] + synonym: "GDP-D-mannose:D-Man-alpha-(1->3)-[D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,2-mannosyltransferase activity" EXACT [EC:2.4.1.131] GO:0004378 : GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity - name: glycolipid 3-alpha-mannosyltransferase activity + name: GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity - def: Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-1,3-D-mannosyl-D-mannose linkage. + def: Catalysis of the reaction: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose = alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP + H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->3)-D-mannosyl-D-mannose linkage. + synonym: "GDP-D-mannose:D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol 3-alpha-mannosyltransferase activity" EXACT systematic_synonym [EC:2.4.1.132] + synonym: "glycolipid 3-alpha-mannosyltransferase activity" EXACT [EC:2.4.1.132] GO:0004381 : fucosylgalactoside 3-alpha-galactosyltransferase activity + synonym: "UDPgalactose:O-alpha-L-fucosyl(1,2)D-galactose alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.37] + synonym: "UDPgalactose:alpha-L-fucosyl-(1,2)-D-galactoside 3-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.37] + synonym: "UDP-galactose:alpha-L-fucosyl-(1,2)-D-galactoside 3-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.37] GO:0004383 : guanylate cyclase activity + xref: Reactome:REACT_115362 "Soluble guanylate cyclase converts GTP to cGMP, Mycobacterium tuberculosis" + xref: Reactome:REACT_115231 "Soluble guanylate cyclase converts GTP to cGMP, Dictyostelium discoideum" GO:0004385 : guanylate kinase activity - xref: Reactome:REACT_110329 "(d)GMP + ATP <=> (d)GDP + ADP [GUK1], Caenorhabditis elegans" - xref: Reactome:REACT_92553 "(d)GDP + ADP <=> (d)GMP + ATP [GUK1], Saccharomyces cerevisiae" - xref: Reactome:REACT_31701 "(d)GMP + ATP <=> (d)GDP + ADP [GUK1], Mycobacterium tuberculosis" - xref: Reactome:REACT_100024 "(d)GMP + ATP <=> (d)GDP + ADP [GUK1], Saccharomyces cerevisiae" - xref: Reactome:REACT_32327 "(d)GDP + ADP <=> (d)GMP + ATP [GUK1], Mycobacterium tuberculosis" + xref: Reactome:REACT_115456 "(d)GMP + ATP <=> (d)GDP + ADP [GUK1], Arabidopsis thaliana" + xref: Reactome:REACT_112127 "(d)GMP + ATP <=> (d)GDP + ADP [GUK1], Oryza sativa" + xref: Reactome:REACT_115196 "(d)GDP + ADP <=> (d)GMP + ATP [GUK1], Arabidopsis thaliana" + xref: Reactome:REACT_114888 "(d)GDP + ADP <=> (d)GMP + ATP [GUK1], Oryza sativa" + xref: Reactome:REACT_31346 "(d)GMP + ATP <=> (d)GDP + ADP [GUK1], Caenorhabditis elegans" GO:0004386 : helicase activity - xref: Reactome:REACT_99106 "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Canis familiaris" - xref: Reactome:REACT_93046 "Cap-bound mRNA is activated by helicases, Rattus norvegicus" - xref: Reactome:REACT_110838 "Addition of the third nucleotide on the nascent transcript, Bos taurus" - xref: Reactome:REACT_91596 "RNA Polymerase II Promoter Opening: First Transition, Canis familiaris" - xref: Reactome:REACT_102116 "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Bos taurus" - xref: Reactome:REACT_100335 "RNA Polymerase II Promoter Opening: First Transition, Dictyostelium discoideum" - xref: Reactome:REACT_91692 "RNA Polymerase II Promoter Opening: First Transition, Bos taurus" - xref: Reactome:REACT_88953 "Addition of the third nucleotide on the nascent transcript, Canis familiaris" - xref: Reactome:REACT_79401 "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Schizosaccharomyces pombe" + xref: Reactome:REACT_113177 "Formation of open bubble structure in DNA by helicases, Caenorhabditis elegans" + xref: Reactome:REACT_112817 "Cap-bound mRNA is activated by helicases, Schizosaccharomyces pombe" + xref: Reactome:REACT_112208 "MCM8 mediated fork unwinding, Drosophila melanogaster" + xref: Reactome:REACT_31554 "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Schizosaccharomyces pombe" + xref: Reactome:REACT_103881 "RNA Polymerase II Promoter Opening: First Transition, Dictyostelium discoideum" GO:0004415 : hyalurononglucosaminidase activity - def: Catalysis of the random hydrolysis of 1,4-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate. + def: Catalysis of the random hydrolysis of (1->4) linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate. GO:0004418 : hydroxymethylbilane synthase activity + xref: Reactome:REACT_113741 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Oryza sativa" + xref: Reactome:REACT_112987 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Escherichia coli" + xref: Reactome:REACT_114514 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Plasmodium falciparum" + xref: Reactome:REACT_113671 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Dictyostelium discoideum" + xref: Reactome:REACT_112891 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Danio rerio" + xref: Reactome:REACT_112379 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Gallus gallus" + xref: Reactome:REACT_114353 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Rattus norvegicus" + xref: Reactome:REACT_112125 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Xenopus tropicalis" + xref: Reactome:REACT_113975 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Arabidopsis thaliana" + xref: Reactome:REACT_114680 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Sus scrofa" + xref: Reactome:REACT_113989 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Mus musculus" + xref: Reactome:REACT_112064 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Mycobacterium tuberculosis" + xref: Reactome:REACT_115346 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Canis familiaris" + xref: Reactome:REACT_113842 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Schizosaccharomyces pombe" + xref: Reactome:REACT_114679 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Drosophila melanogaster" + xref: Reactome:REACT_112182 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Saccharomyces cerevisiae" + xref: Reactome:REACT_111975 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Bos taurus" + xref: Reactome:REACT_114418 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Staphylococcus aureus N315" GO:0004419 : hydroxymethylglutaryl-CoA lyase activity - xref: Reactome:REACT_86954 "HMG CoA => acetoacetic acid+ acetyl CoA, Mus musculus" - xref: Reactome:REACT_99837 "HMG CoA => acetoacetic acid+ acetyl CoA, Danio rerio" - xref: Reactome:REACT_104457 "HMG CoA => acetoacetic acid+ acetyl CoA, Drosophila melanogaster" - xref: Reactome:REACT_99898 "HMG CoA => acetoacetic acid+ acetyl CoA, Caenorhabditis elegans" - xref: Reactome:REACT_90800 "HMG CoA => acetoacetic acid+ acetyl CoA, Rattus norvegicus" - xref: Reactome:REACT_31175 "HMG CoA => acetoacetic acid+ acetyl CoA, Taeniopygia guttata" - xref: Reactome:REACT_91737 "HMG CoA => acetoacetic acid+ acetyl CoA, Bos taurus" - xref: Reactome:REACT_89460 "HMG CoA => acetoacetic acid+ acetyl CoA, Xenopus tropicalis" - xref: Reactome:REACT_2103 "HMG CoA => acetoacetic acid+ acetyl CoA, Homo sapiens" - xref: Reactome:REACT_100202 "HMG CoA => acetoacetic acid+ acetyl CoA, Dictyostelium discoideum" - xref: Reactome:REACT_110966 "HMG CoA => acetoacetic acid+ acetyl CoA, Arabidopsis thaliana" - xref: Reactome:REACT_29720 "HMG CoA => acetoacetic acid+ acetyl CoA, Oryza sativa" - xref: Reactome:REACT_108952 "HMG CoA => acetoacetic acid+ acetyl CoA, Gallus gallus" - xref: Reactome:REACT_105243 "HMG CoA => acetoacetic acid+ acetyl CoA, Canis familiaris" + xref: Reactome:REACT_2103 "HMG CoA => acetoacetic acid + acetyl CoA, Homo sapiens" + xref: Reactome:REACT_99898 "HMG CoA => acetoacetic acid + acetyl CoA, Caenorhabditis elegans" + xref: Reactome:REACT_89460 "HMG CoA => acetoacetic acid + acetyl CoA, Xenopus tropicalis" + xref: Reactome:REACT_31175 "HMG CoA => acetoacetic acid + acetyl CoA, Taeniopygia guttata" + xref: Reactome:REACT_105243 "HMG CoA => acetoacetic acid + acetyl CoA, Canis familiaris" + xref: Reactome:REACT_29720 "HMG CoA => acetoacetic acid + acetyl CoA, Oryza sativa" + xref: Reactome:REACT_108952 "HMG CoA => acetoacetic acid + acetyl CoA, Gallus gallus" + xref: Reactome:REACT_86954 "HMG CoA => acetoacetic acid + acetyl CoA, Mus musculus" + xref: Reactome:REACT_104457 "HMG CoA => acetoacetic acid + acetyl CoA, Drosophila melanogaster" + xref: Reactome:REACT_100202 "HMG CoA => acetoacetic acid + acetyl CoA, Dictyostelium discoideum" + xref: Reactome:REACT_90800 "HMG CoA => acetoacetic acid + acetyl CoA, Rattus norvegicus" + xref: Reactome:REACT_110966 "HMG CoA => acetoacetic acid + acetyl CoA, Arabidopsis thaliana" + xref: Reactome:REACT_91737 "HMG CoA => acetoacetic acid + acetyl CoA, Bos taurus" + xref: Reactome:REACT_99837 "HMG CoA => acetoacetic acid + acetyl CoA, Danio rerio" GO:0004421 : hydroxymethylglutaryl-CoA synthase activity - xref: Reactome:REACT_103557 "acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH, Caenorhabditis elegans" - xref: Reactome:REACT_81885 "Condensation of acetyl CoA with acetoacetyl CoA to form HMG-CoA, Caenorhabditis elegans" GO:0004427 : inorganic diphosphatase activity - xref: Reactome:REACT_96188 "pyrophosphate + H2O => 2 orthophosphate [cytosolic], Caenorhabditis elegans" + xref: Reactome:REACT_115460 "pyrophosphate + H2O => 2 orthophosphate [cytosolic], Plasmodium falciparum" + xref: Reactome:REACT_114811 "pyrophosphate + H2O => 2 orthophosphate [cytosolic], Oryza sativa" + xref: Reactome:REACT_95722 "pyrophosphate + H2O => 2 orthophosphate [cytosolic], Caenorhabditis elegans" + xref: Reactome:REACT_113725 "pyrophosphate + H2O => 2 orthophosphate [cytosolic], Mycobacterium tuberculosis" + xref: Reactome:REACT_113089 "pyrophosphate + H2O => 2 orthophosphate [cytosolic], Arabidopsis thaliana" GO:0004428 : inositol or phosphatidylinositol kinase activity - def: Catalysis of the phosphorylation of myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol. + def: OBSOLETE. Catalysis of the phosphorylation of myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol. + comment: This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids. - subset: gosubset_prok - is_a: GO:0016301 + is_obsolete: true + consider: GO:0016307 + consider: GO:0019140 + consider: GO:0052742 + consider: GO:0052813 GO:0004435 : phosphatidylinositol phospholipase C activity - xref: Reactome:REACT_73633 "PLC-gamma hydrolyses PIP2, Gallus gallus" - xref: Reactome:REACT_78307 "PLC-gamma hydrolyses PIP2, Rattus norvegicus" - xref: Reactome:REACT_47190 "PLC-gamma hydrolyses PIP2, Bos taurus" - xref: Reactome:REACT_98027 "PLC-gamma hydrolyses PIP2, Taeniopygia guttata" - xref: Reactome:REACT_33727 "PIP2 hydrolysis, Sus scrofa" - xref: Reactome:REACT_16916 "PLC-gamma hydrolyses PIP2, Homo sapiens" - xref: Reactome:REACT_96001 "PLC-gamma hydrolyses PIP2, Sus scrofa" - xref: Reactome:REACT_83793 "PLC-gamma hydrolyses PIP2, Mus musculus" - xref: Reactome:REACT_94157 "PLC-gamma hydrolyses PIP2, Danio rerio" - xref: Reactome:REACT_88110 "PLC-gamma hydrolyses PIP2, Drosophila melanogaster" - xref: Reactome:REACT_40672 "PLC-gamma hydrolyses PIP2, Canis familiaris" - xref: Reactome:REACT_96266 "PLC-gamma hydrolyses PIP2, Xenopus tropicalis" + xref: Reactome:REACT_114034 "PIP2 hydrolysis, Schizosaccharomyces pombe" + xref: Reactome:REACT_113026 "PLC-gamma1 hydrolyses PIP2, Drosophila melanogaster" + xref: Reactome:REACT_113176 "PLC-gamma1 hydrolyses PIP2, Arabidopsis thaliana" + xref: Reactome:REACT_114083 "Active PLCG1 hydrolyses PIP2, Oryza sativa" + xref: Reactome:REACT_114237 "Active PLCG1 hydrolyses PIP2, Caenorhabditis elegans" + xref: Reactome:REACT_113179 "Active PLCG1 hydrolyses PIP2, Saccharomyces cerevisiae" + xref: Reactome:REACT_113959 "PIP2 hydrolysis, Arabidopsis thaliana" + xref: Reactome:REACT_113134 "PIP2 hydrolysis, Schizosaccharomyces pombe" + xref: Reactome:REACT_114608 "PIP2 hydrolysis, Saccharomyces cerevisiae" + xref: Reactome:REACT_111977 "PIP2 hydrolysis, Drosophila melanogaster" + xref: Reactome:REACT_112016 "Active PLCG1 hydrolyses PIP2, Arabidopsis thaliana" + xref: Reactome:REACT_112120 "PLC-gamma1 hydrolyses PIP2, Saccharomyces cerevisiae" + xref: Reactome:REACT_112432 "PLC-gamma1 hydrolyses PIP2, Oryza sativa" + xref: Reactome:REACT_113733 "Active PLCG1 hydrolyses PIP2, Dictyostelium discoideum" + xref: Reactome:REACT_90807 "PIP2 hydrolysis, Sus scrofa" + xref: Reactome:REACT_113618 "Active PLCG1 hydrolyses PIP2, Plasmodium falciparum" + xref: Reactome:REACT_114783 "PIP2 hydrolysis, Caenorhabditis elegans" + xref: Reactome:REACT_114264 "Active PLCG1 hydrolyses PIP2, Schizosaccharomyces pombe" + xref: Reactome:REACT_114663 "PIP2 hydrolysis, Plasmodium falciparum" + xref: Reactome:REACT_114329 "PIP2 hydrolysis, Dictyostelium discoideum" + xref: Reactome:REACT_113870 "PLC-gamma1 hydrolyses PIP2, Schizosaccharomyces pombe" + xref: Reactome:REACT_113201 "PLC-gamma1 hydrolyses PIP2, Plasmodium falciparum" + xref: Reactome:REACT_113925 "Active PLCG1 hydrolyses PIP2, Drosophila melanogaster" + xref: Reactome:REACT_115119 "PIP2 hydrolysis, Saccharomyces cerevisiae" + xref: Reactome:REACT_113827 "PIP2 hydrolysis, Dictyostelium discoideum" + xref: Reactome:REACT_114101 "PLC-gamma1 hydrolyses PIP2, Caenorhabditis elegans" + xref: Reactome:REACT_112586 "PIP2 hydrolysis, Oryza sativa" + xref: Reactome:REACT_113580 "PLC-gamma1 hydrolyses PIP2, Dictyostelium discoideum" GO:0004437 : inositol or phosphatidylinositol phosphatase activity - def: Catalysis of the removal of a phosphate group from phosphorylated myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol. + def: OBSOLETE. Catalysis of the removal of a phosphate group from phosphorylated myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol. + comment: This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids. - subset: gosubset_prok - is_a: GO:0016791 + is_obsolete: true + consider: GO:0034593 + consider: GO:0034594 + consider: GO:0052744 + consider: GO:0052745 GO:0004449 : isocitrate dehydrogenase (NAD+) activity + xref: Reactome:REACT_113241 "isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3], Canis familiaris" + xref: Reactome:REACT_112010 "isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3], Bos taurus" GO:0004450 : isocitrate dehydrogenase (NADP+) activity + xref: Reactome:REACT_112495 "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+, Oryza sativa" + xref: Reactome:REACT_115270 "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+, Oryza sativa" + xref: Reactome:REACT_112251 "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+, Plasmodium falciparum" + xref: Reactome:REACT_115223 "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+, Plasmodium falciparum" + xref: Reactome:REACT_113535 "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+, Arabidopsis thaliana" + xref: Reactome:REACT_114848 "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+, Arabidopsis thaliana" GO:0004452 : isopentenyl-diphosphate delta-isomerase activity - synonym: "ipp isomerase activity" EXACT [EC:5.3.3.2] - synonym: "isopentenylpyrophosphate Delta-isomerase activity" EXACT [EC:5.3.3.2] GO:0004459 : L-lactate dehydrogenase activity - xref: Reactome:REACT_79336 "(S)-Lactate + NAD+ <=> Pyruvate + NADH + H+, Plasmodium falciparum" - xref: Reactome:REACT_44482 "Pyruvate + NADH + H+ <=> (S)-Lactate + NAD+, Plasmodium falciparum" + xref: Reactome:REACT_115372 "Pyruvate + NADH + H+ <=> (S)-Lactate + NAD+, Caenorhabditis elegans" + xref: Reactome:REACT_112887 "Pyruvate + NADH + H+ <=> (S)-Lactate + NAD+, Arabidopsis thaliana" + xref: Reactome:REACT_113500 "Pyruvate + NADH + H+ <=> (S)-Lactate + NAD+, Oryza sativa" + xref: Reactome:REACT_115097 "(S)-Lactate + NAD+ <=> Pyruvate + NADH + H+, Caenorhabditis elegans" + xref: Reactome:REACT_112284 "Pyruvate + NADH + H+ <=> (S)-Lactate + NAD+, Drosophila melanogaster" + xref: Reactome:REACT_113309 "(S)-Lactate + NAD+ <=> Pyruvate + NADH + H+, Oryza sativa" + xref: Reactome:REACT_112343 "(S)-Lactate + NAD+ <=> Pyruvate + NADH + H+, Drosophila melanogaster" + xref: Reactome:REACT_112780 "(S)-Lactate + NAD+ <=> Pyruvate + NADH + H+, Arabidopsis thaliana" GO:0004463 : leukotriene-A4 hydrolase activity + xref: Reactome:REACT_115125 "LTA4 is hydrolyzed to LTB4, Saccharomyces cerevisiae" + xref: Reactome:REACT_113583 "LTA4 is hydrolyzed to LTB4, Dictyostelium discoideum" + xref: Reactome:REACT_115164 "LTA4 is hydrolyzed to LTB4, Schizosaccharomyces pombe" + xref: Reactome:REACT_113737 "LTA4 is hydrolyzed to LTB4, Mycobacterium tuberculosis" GO:0004467 : long-chain fatty acid-CoA ligase activity - xref: Reactome:REACT_92028 "3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS), Sus scrofa" - xref: Reactome:REACT_89029 "DHCA is conjugated with Coenzyme A (SLC27A5 BACS), Sus scrofa" - xref: Reactome:REACT_93457 "palmitate + CoASH + ATP => palmitoyl-CoA + AMP + pyrophosphate + H2O [ACSL5], Oryza sativa" - xref: Reactome:REACT_88013 "TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS), Sus scrofa" - xref: Reactome:REACT_109703 "THCA is conjugated with Coenzyme A (SLC27A5 BACS), Bos taurus" - xref: Reactome:REACT_108001 "Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS), Sus scrofa" - xref: Reactome:REACT_88306 "palmitate + CoASH + ATP => palmitoyl-CoA + AMP + pyrophosphate + H2O [ACSL5], Arabidopsis thaliana" - xref: Reactome:REACT_108128 "palmitate + CoASH + ATP => palmitoyl-CoA + AMP + pyrophosphate + H2O [ACSL5], Drosophila melanogaster" - xref: Reactome:REACT_105550 "THCA is conjugated with Coenzyme A (SLC27A5 BACS), Sus scrofa" + xref: Reactome:REACT_114641 "3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS), Saccharomyces cerevisiae" + xref: Reactome:REACT_114941 "THCA is conjugated with Coenzyme A (SLC27A2 VLCS), Saccharomyces cerevisiae" + xref: Reactome:REACT_113562 "DHCA is conjugated with Coenzyme A (SLC27A5 BACS), Saccharomyces cerevisiae" + xref: Reactome:REACT_115464 "palmitate + CoASH + ATP => palmitoyl-CoA + AMP + pyrophosphate + H2O [ACSL3], Xenopus tropicalis" + xref: Reactome:REACT_100377 "THCA is conjugated with Coenzyme A (SLC27A5 BACS), Bos taurus" + xref: Reactome:REACT_113477 "Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS), Saccharomyces cerevisiae" + xref: Reactome:REACT_113165 "TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS), Saccharomyces cerevisiae" + xref: Reactome:REACT_113402 "DHCA is conjugated with Coenzyme A (SLC27A2 VLCS), Taeniopygia guttata" + xref: Reactome:REACT_112314 "3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS), Taeniopygia guttata" + xref: Reactome:REACT_112234 "palmitate + CoASH + ATP => palmitoyl-CoA + AMP + pyrophosphate + H2O [ACSL5], Dictyostelium discoideum" + xref: Reactome:REACT_115449 "THCA is conjugated with Coenzyme A (SLC27A2 VLCS), Taeniopygia guttata" + xref: Reactome:REACT_114408 "3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS), Saccharomyces cerevisiae" + xref: Reactome:REACT_113283 "DHCA is conjugated with Coenzyme A (SLC27A2 VLCS), Saccharomyces cerevisiae" + xref: Reactome:REACT_112002 "TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS), Saccharomyces cerevisiae" + xref: Reactome:REACT_112197 "palmitate + CoASH + ATP => palmitoyl-CoA + AMP + pyrophosphate + H2O [ACSL3], Mycobacterium tuberculosis" + xref: Reactome:REACT_112696 "THCA is conjugated with Coenzyme A (SLC27A5 BACS), Saccharomyces cerevisiae" + xref: Reactome:REACT_113604 "TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS), Taeniopygia guttata" + xref: Reactome:REACT_112185 "palmitate + CoASH + ATP => palmitoyl-CoA + AMP + pyrophosphate + H2O [ACSL3], Dictyostelium discoideum" + xref: Reactome:REACT_113433 "palmitate + CoASH + ATP => palmitoyl-CoA + AMP + pyrophosphate + H2O [ACSL3], Plasmodium falciparum" GO:0004477 : methenyltetrahydrofolate cyclohydrolase activity - xref: Reactome:REACT_84517 "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate, Caenorhabditis elegans" - xref: Reactome:REACT_32385 "10-formylTHF polyglutamate <=> 5,10-methenylTHF polyglutamate + H2O, Caenorhabditis elegans" - xref: Reactome:REACT_102452 "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate, Saccharomyces cerevisiae" - xref: Reactome:REACT_29810 "10-formylTHF polyglutamate <=> 5,10-methenylTHF polyglutamate + H2O, Oryza sativa" - xref: Reactome:REACT_33047 "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate, Oryza sativa" - xref: Reactome:REACT_96618 "10-formylTHF polyglutamate <=> 5,10-methenylTHF polyglutamate + H2O, Staphylococcus aureus N315" - xref: Reactome:REACT_106128 "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate, Dictyostelium discoideum" - xref: Reactome:REACT_77264 "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate, Staphylococcus aureus N315" - xref: Reactome:REACT_92875 "10-formylTHF polyglutamate <=> 5,10-methenylTHF polyglutamate + H2O, Arabidopsis thaliana" - xref: Reactome:REACT_78768 "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate, Escherichia coli" - xref: Reactome:REACT_30136 "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate, Arabidopsis thaliana" - xref: Reactome:REACT_94612 "10-formylTHF polyglutamate <=> 5,10-methenylTHF polyglutamate + H2O, Dictyostelium discoideum" - xref: Reactome:REACT_106007 "10-formylTHF polyglutamate <=> 5,10-methenylTHF polyglutamate + H2O, Escherichia coli" + xref: Reactome:REACT_112952 "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate, Xenopus tropicalis" + xref: Reactome:REACT_114540 "10-formylTHF polyglutamate <=> 5,10-methenylTHF polyglutamate + H2O, Xenopus tropicalis" + xref: Reactome:REACT_100157 "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate, Saccharomyces cerevisiae" GO:0004478 : methionine adenosyltransferase activity - xref: Reactome:REACT_34627 "SAM is sythesized from methionine's reaction with ATP, Plasmodium falciparum" - xref: Reactome:REACT_79723 "SAM is sythesized from methionine's reaction with ATP, Arabidopsis thaliana" - xref: Reactome:REACT_93771 "SAM is sythesized from methionine's reaction with ATP, Saccharomyces cerevisiae" - xref: Reactome:REACT_106475 "SAM is sythesized from methionine's reaction with ATP, Dictyostelium discoideum" - xref: Reactome:REACT_33958 "SAM is sythesized from methionine's reaction with ATP, Oryza sativa" + xref: Reactome:REACT_77762 "SAM is sythesized from methionine's reaction with ATP, Saccharomyces cerevisiae" + xref: Reactome:REACT_115032 "SAM is sythesized from methionine's reaction with ATP, Staphylococcus aureus N315" GO:0004482 : mRNA (guanine-N7-)-methyltransferase activity - xref: Reactome:REACT_108598 "Methylation of GMP-cap by RNA Methyltransferase, Canis familiaris" - xref: Reactome:REACT_94906 "Methylation of GMP-cap by RNA Methyltransferase, Bos taurus" GO:0004484 : mRNA guanylyltransferase activity - xref: Reactome:REACT_97660 "Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA, Saccharomyces cerevisiae" + xref: Reactome:REACT_88083 "Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA, Saccharomyces cerevisiae" GO:0004485 : methylcrotonoyl-CoA carboxylase activity + xref: Reactome:REACT_112537 "beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA], Mycobacterium tuberculosis" GO:0004486 : methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity - xref: Reactome:REACT_87536 "5,10-methenylTHF polyglutamate + NADPH + H+ <=> 5,10-methyleneTHF polyglutamate + NADP+, Staphylococcus aureus N315" - xref: Reactome:REACT_79429 "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+, Sus scrofa" - xref: Reactome:REACT_33699 "5,10-methenylTHF polyglutamate + NADPH + H+ <=> 5,10-methyleneTHF polyglutamate + NADP+, Arabidopsis thaliana" - xref: Reactome:REACT_85524 "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+, Dictyostelium discoideum" - xref: Reactome:REACT_102502 "5,10-methenylTHF polyglutamate + NADPH + H+ <=> 5,10-methyleneTHF polyglutamate + NADP+, Caenorhabditis elegans" - xref: Reactome:REACT_103459 "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+, Escherichia coli" - xref: Reactome:REACT_109615 "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+, Arabidopsis thaliana" - xref: Reactome:REACT_32157 "5,10-methenylTHF polyglutamate + NADPH + H+ <=> 5,10-methyleneTHF polyglutamate + NADP+, Oryza sativa" - xref: Reactome:REACT_89320 "5,10-methenylTHF polyglutamate + NADPH + H+ <=> 5,10-methyleneTHF polyglutamate + NADP+, Dictyostelium discoideum" - xref: Reactome:REACT_81578 "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+, Oryza sativa" - xref: Reactome:REACT_92013 "5,10-methenylTHF polyglutamate + NADPH + H+ <=> 5,10-methyleneTHF polyglutamate + NADP+, Escherichia coli" - xref: Reactome:REACT_79552 "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+, Caenorhabditis elegans" - xref: Reactome:REACT_99867 "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+, Staphylococcus aureus N315" - xref: Reactome:REACT_91104 "5,10-methenylTHF polyglutamate + NADPH + H+ <=> 5,10-methyleneTHF polyglutamate + NADP+, Sus scrofa" + xref: Reactome:REACT_114836 "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+, Xenopus tropicalis" + xref: Reactome:REACT_85239 "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+, Sus scrofa" + xref: Reactome:REACT_112142 "5,10-methenylTHF polyglutamate + NADPH + H+ <=> 5,10-methyleneTHF polyglutamate + NADP+, Xenopus tropicalis" + xref: Reactome:REACT_96601 "5,10-methenylTHF polyglutamate + NADPH + H+ <=> 5,10-methyleneTHF polyglutamate + NADP+, Sus scrofa" GO:0004490 : methylglutaconyl-CoA hydratase activity + xref: Reactome:REACT_114406 "beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA, Mycobacterium tuberculosis" GO:0004493 : methylmalonyl-CoA epimerase activity - synonym: "dl-methylmalonyl-CoA racemase activity" EXACT [EC:5.1.99.1] GO:0004494 : methylmalonyl-CoA mutase activity - xref: Reactome:REACT_102288 "L-methylmalonyl-CoA <=> succinyl-CoA, Sus scrofa" + xref: Reactome:REACT_114493 "L-methylmalonyl-CoA <=> succinyl-CoA, Xenopus tropicalis" + xref: Reactome:REACT_95870 "L-methylmalonyl-CoA <=> succinyl-CoA, Sus scrofa" GO:0004497 : monooxygenase activity - xref: Reactome:REACT_105821 "CYP3A43 catalyzes the 6beta-hydroxylation of testosterone, Rattus norvegicus" - xref: Reactome:REACT_86737 "FMO2 S-oxidizes the antithyroid drug methimazole, Xenopus tropicalis" - xref: Reactome:REACT_102176 "CYP4F11 omega-hydroxylates 3-hydroxypalmitate, Canis familiaris" - xref: Reactome:REACT_89003 "CYP4F11 omega-hydroxylates 3-hydroxypalmitate, Bos taurus" - xref: Reactome:REACT_81830 "CYP3A43 catalyzes the 6beta-hydroxylation of testosterone, Caenorhabditis elegans" - xref: Reactome:REACT_104843 "CYP4F11 omega-hydroxylates 3-hydroxypalmitate, Sus scrofa" - xref: Reactome:REACT_84580 "CYP3A43 catalyzes the 6beta-hydroxylation of testosterone, Bos taurus" - xref: Reactome:REACT_77846 "CYP3A43 catalyzes the 6beta-hydroxylation of testosterone, Canis familiaris" - xref: Reactome:REACT_85402 "CYP2W1 can oxidize indole, Taeniopygia guttata" + xref: Reactome:REACT_113028 "CYP3A43 catalyzes the 6beta-hydroxylation of testosterone, Taeniopygia guttata" + xref: Reactome:REACT_115238 "FMO2 S-oxidizes the antithyroid drug methimazole, Danio rerio" GO:0004498 : calcidiol 1-monooxygenase activity - synonym: "1-hydroxylase-25-hydroxyvitamin D3" RELATED [EC:1.14.13.13] + synonym: "1-hydroxylase-25-hydroxyvitamin D3 activity" RELATED [EC:1.14.13.13] - xref: Reactome:REACT_30110 "Further hydroxylation of calcidiol in kidney to form calcitriol, Caenorhabditis elegans" GO:0004499 : flavin-containing monooxygenase activity - xref: Reactome:REACT_90669 "FMO1 N-oxidizes the anti-cancer drug tamoxifen, Dictyostelium discoideum" + xref: Reactome:REACT_114014 "FMO1 N-oxidizes the anti-cancer drug tamoxifen, Danio rerio" + xref: Reactome:REACT_84504 "FMO1 N-oxidizes the anti-cancer drug tamoxifen, Dictyostelium discoideum" + xref: Reactome:REACT_113438 "FMO3 N-oxidizes the tertiary amine trimethylamine, Taeniopygia guttata" + xref: Reactome:REACT_114556 "FMO3 N-oxidizes the tertiary amine trimethylamine, Danio rerio" GO:0004506 : squalene monooxygenase activity - xref: Reactome:REACT_80174 "Squalene is oxidized to its epoxide, Dictyostelium discoideum" + xref: Reactome:REACT_32861 "Squalene is oxidized to its epoxide, Dictyostelium discoideum" GO:0004507 : steroid 11-beta-monooxygenase activity - xref: Reactome:REACT_80041 "Hydroxylation of 11-deoxycorticosterone to form corticosterone, Caenorhabditis elegans" - xref: Reactome:REACT_77534 "11-deoxycortisol is oxidised to cortisol by CYP11B1, Caenorhabditis elegans" GO:0004508 : steroid 17-alpha-monooxygenase activity - xref: Reactome:REACT_86382 "Hydroxylation of pregnenolone to form 17alpha-hydroxypregnenolone, Sus scrofa" + xref: Reactome:REACT_113135 "Side chain cleavage of 17alpha-hydroxypregnenolone to yield DHA, Gallus gallus" + xref: Reactome:REACT_114963 "Hydroxylation of pregnenolone to form 17alpha-hydroxypregnenolone, Gallus gallus" + xref: Reactome:REACT_112434 "Side chain cleavage of 17alpha-hydroxyprogesterone to form 4-Androstene-3, 17-dione, Gallus gallus" + xref: Reactome:REACT_113443 "Hydroxylation of progesterone to form 17alpha-hydroxyprogesterone, Gallus gallus" + xref: Reactome:REACT_85525 "Hydroxylation of pregnenolone to form 17alpha-hydroxypregnenolone, Sus scrofa" GO:0004510 : tryptophan 5-monooxygenase activity + xref: Reactome:REACT_112261 "Tryptophan is hydroxylated, Dictyostelium discoideum" GO:0004511 : tyrosine 3-monooxygenase activity + xref: Reactome:REACT_114697 "Tyrosine is hydroxylated to dopa, Dictyostelium discoideum" GO:0004516 : nicotinate phosphoribosyltransferase activity - xref: Reactome:REACT_89648 "A phosphoribosyl group is added to nicotinate to form nicotinate mononucleotide (NaMN), Caenorhabditis elegans" + xref: Reactome:REACT_79471 "A phosphoribosyl group is added to nicotinate to form nicotinate mononucleotide (NaMN), Caenorhabditis elegans" GO:0004517 : nitric-oxide synthase activity - xref: Reactome:REACT_83313 "NO biosynthesis, Dictyostelium discoideum" - xref: Reactome:REACT_30015 "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO), Staphylococcus aureus N315" - xref: Reactome:REACT_86943 "NO biosynthesis, Drosophila melanogaster" - xref: Reactome:REACT_84069 "NO biosynthesis, Sus scrofa" - xref: Reactome:REACT_30098 "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO), Escherichia coli" + xref: Reactome:REACT_30996 "NO biosynthesis, Sus scrofa" + xref: Reactome:REACT_113518 "NO biosynthesis, Taeniopygia guttata" GO:0004519 : endonuclease activity + xref: Reactome:REACT_115382 "Removal of 3'-phosphoglycolate (PG) moiety from DSB ends, Sus scrofa" + xref: Reactome:REACT_113127 "Removal of 3'-phosphoglycolate (PG) moiety from DSB ends, Taeniopygia guttata" + xref: Reactome:REACT_112509 "Cleavage of mRNA at the 3'-end, Arabidopsis thaliana" + xref: Reactome:REACT_115221 "Removal of 3'-phosphoglycolate (PG) moiety from DSB ends, Mus musculus" + xref: Reactome:REACT_112366 "Removal of 3'-phosphoglycolate (PG) moiety from DSB ends, Danio rerio" + xref: Reactome:REACT_113819 "Cleavage of mRNA at the 3'-end, Drosophila melanogaster" + xref: Reactome:REACT_112615 "Removal of 3'-phosphoglycolate (PG) moiety from DSB ends, Rattus norvegicus" + xref: Reactome:REACT_113480 "Removal of 3'-phosphoglycolate (PG) moiety from DSB ends, Gallus gallus" + xref: Reactome:REACT_115226 "Removal of 3'-phosphoglycolate (PG) moiety from DSB ends, Bos taurus" + xref: Reactome:REACT_112782 "Removal of 3'-phosphoglycolate (PG) moiety from DSB ends, Xenopus tropicalis" + xref: Reactome:REACT_114931 "Removal of 3'-phosphoglycolate (PG) moiety from DSB ends, Canis familiaris" GO:0004520 : endodeoxyribonuclease activity - xref: Reactome:REACT_104308 "APE1 mediated endonucleolytic cleavage at the 5' side of the base-free deoxyribose residue, Oryza sativa" - xref: Reactome:REACT_91600 "5'-incision of DNA by ERCC1-XPF in GG-NER, Bos taurus" - xref: Reactome:REACT_109157 "3' incision of the lesioned strand of DNA in TC-NER, Saccharomyces cerevisiae" - xref: Reactome:REACT_102405 "APE1 mediated endonucleolytic cleavage at the 5' side of the base-free deoxyribose residue, Plasmodium falciparum" - xref: Reactome:REACT_84229 "5' incision leading to excision of DNA fragment with lesion in TC-NER, Sus scrofa" - xref: Reactome:REACT_83782 "APE1 mediated endonucleolytic cleavage at the 5' side of the base-free deoxyribose residue, Arabidopsis thaliana" - xref: Reactome:REACT_104620 "5' incision leading to excision of DNA fragment with lesion in TC-NER, Saccharomyces cerevisiae" + xref: Reactome:REACT_115479 "3' incision of the lesioned strand of DNA in TC-NER, Gallus gallus" + xref: Reactome:REACT_32833 "3' incision of the lesioned strand of DNA in TC-NER, Saccharomyces cerevisiae" + xref: Reactome:REACT_98405 "5' incision leading to excision of DNA fragment with lesion in TC-NER, Saccharomyces cerevisiae" + xref: Reactome:REACT_112152 "3' incision of the lesioned strand of DNA in TC-NER, Taeniopygia guttata" + xref: Reactome:REACT_78421 "5' incision leading to excision of DNA fragment with lesion in TC-NER, Sus scrofa" + xref: Reactome:REACT_112122 "5'-incision of DNA by ERCC1-XPF in GG-NER, Xenopus tropicalis" + xref: Reactome:REACT_115154 "5' incision leading to excision of DNA fragment with lesion in TC-NER, Gallus gallus" + xref: Reactome:REACT_115463 "5' incision leading to excision of DNA fragment with lesion in TC-NER, Taeniopygia guttata" GO:0004525 : ribonuclease III activity - xref: Reactome:REACT_85876 "Microprocessor complex cleaves pri-miRNA to pre-miRNA, Caenorhabditis elegans" + xref: Reactome:REACT_92676 "Microprocessor complex cleaves pri-miRNA to pre-miRNA, Caenorhabditis elegans" + xref: Reactome:REACT_115273 "Dicer cleaves pre-miRNA to yield mature miRNA, Caenorhabditis elegans" GO:0004534 : 5'-3' exoribonuclease activity - xref: Reactome:REACT_87101 "5' to 3' Exoribonuclease Digestion of Decapped mRNA, Rattus norvegicus" + xref: Reactome:REACT_112806 "5' to 3' Exoribonuclease Digestion of Decapped mRNA, Dictyostelium discoideum" + xref: Reactome:REACT_112693 "5' to 3' Exoribonuclease Digestion of Decapped mRNA, Plasmodium falciparum" GO:0004535 : poly(A)-specific ribonuclease activity + xref: Reactome:REACT_111967 "Deadenylation of mRNA by PARN, Taeniopygia guttata" + xref: Reactome:REACT_112457 "Partial Deadenylation of mRNA by the PAN2-PAN3 Complex, Drosophila melanogaster" + xref: Reactome:REACT_114879 "Deadenylation of mRNA by the CCR4-NOT Complex, Taeniopygia guttata" GO:0004551 : nucleotide diphosphatase activity - xref: Reactome:REACT_97226 "FAD can be hydrolyzed back to FMN, Schizosaccharomyces pombe" - xref: Reactome:REACT_106646 "FAD can be hydrolyzed back to FMN, Caenorhabditis elegans" + xref: Reactome:REACT_114734 "FAD can be hydrolyzed back to FMN, Xenopus tropicalis" + xref: Reactome:REACT_105775 "FAD can be hydrolyzed back to FMN, Schizosaccharomyces pombe" GO:0004555 : alpha,alpha-trehalase activity + xref: Reactome:REACT_113083 "trehalose + H2O => 2 D-glucose, Escherichia coli" GO:0004556 : alpha-amylase activity - def: Catalysis of the endohydrolysis of 1,4-alpha-D-glucosidic linkages in polysaccharides containing three or more 1,4-alpha-linked D-glucose units. + def: Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units. GO:0004558 : alpha-glucosidase activity - def: Catalysis of the hydrolysis of terminal, non-reducing 1,4-linked alpha-D-glucose residues with release of alpha-D-glucose. + def: Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose. - xref: Reactome:REACT_84980 "maltose + H2O => 2 D-glucose (maltase-glucoamylase), Xenopus tropicalis" - xref: Reactome:REACT_31062 "maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase), Xenopus tropicalis" - xref: Reactome:REACT_32647 "maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase), Rattus norvegicus" - xref: Reactome:REACT_98945 "maltose + H2O => 2 D-glucose (maltase-glucoamylase), Rattus norvegicus" + xref: Reactome:REACT_114036 "maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase), Taeniopygia guttata" + xref: Reactome:REACT_112486 "maltose + H2O => 2 D-glucose (sucrase-isomaltase), Taeniopygia guttata" + xref: Reactome:REACT_113312 "Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose, Taeniopygia guttata" GO:0004568 : chitinase activity - def: Catalysis of the hydrolysis of 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. + def: Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. GO:0004571 : mannosyl-oligosaccharide 1,2-alpha-mannosidase activity - def: Catalysis of the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2). + def: Catalysis of the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2). GO:0004572 : mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity - def: Catalysis of the hydrolysis of the terminal 1,3- and 1,6-linked alpha-D-mannose residues in the mannosyl-oligosaccharide Man(5)(GlcNAc)(3). + def: Catalysis of the hydrolysis of the terminal (1->3)- and (1->6)-linked alpha-D-mannose residues in the mannosyl-oligosaccharide Man(5)(GlcNAc)(3). - synonym: "alpha1-3,6-mannosidase activity" EXACT [EC:3.2.1.114] + synonym: "mannosyl-oligosaccharide (1->3,6)-alpha-mannosidase activity" EXACT [] + synonym: "mannosyl-oligosaccharide (1->3)-(1->6)-alpha-mannosidase activity" EXACT [] + synonym: "alpha-(1,3/6)-mannosidase activity" EXACT [EC:3.2.1.114] + synonym: "mannosyl-oligosaccharide (1->3/6)-alpha-mannosidase activity" EXACT [] GO:0004574 : oligo-1,6-glucosidase activity - def: Catalysis of the hydrolysis of 1,6-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose. + def: Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose. GO:0004575 : sucrose alpha-glucosidase activity + xref: Reactome:REACT_113531 "sucrose + H2O => glucose + fructose, Taeniopygia guttata" GO:0004582 : dolichyl-phosphate beta-D-mannosyltransferase activity - xref: Reactome:REACT_95320 "dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose, Sus scrofa" - xref: Reactome:REACT_30274 "dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose, Dictyostelium discoideum" + xref: Reactome:REACT_92201 "dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose, Sus scrofa" + xref: Reactome:REACT_95377 "dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose, Dictyostelium discoideum" GO:0004584 : dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity - synonym: "oligomannosylsynthase activity" EXACT [EC:2.4.1.130] + synonym: "oligomannosylsynthase activity" BROAD [EC:2.4.1.130] GO:0004586 : ornithine decarboxylase activity + xref: Reactome:REACT_112162 "ornithine => putrescine + CO2, Staphylococcus aureus N315" + xref: Reactome:REACT_112888 "ornithine => putrescine + CO2, Drosophila melanogaster" GO:0004587 : ornithine-oxo-acid transaminase activity - xref: Reactome:REACT_101723 "ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT], Dictyostelium discoideum" + xref: Reactome:REACT_104089 "ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT], Dictyostelium discoideum" + xref: Reactome:REACT_113272 "ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT], Staphylococcus aureus N315" + xref: Reactome:REACT_112121 "glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT], Staphylococcus aureus N315" GO:0004594 : pantothenate kinase activity - xref: Reactome:REACT_96176 "Pantothenate is phosphorylated [PANK2], Bos taurus" + xref: Reactome:REACT_112376 "Pantothenate is phosphorylated [PANK2], Plasmodium falciparum" + xref: Reactome:REACT_102890 "Pantothenate is phosphorylated [PANK2], Bos taurus" + xref: Reactome:REACT_113306 "Pantothenate is phosphorylated [PANK1;3;4], Xenopus tropicalis" + xref: Reactome:REACT_112157 "Pantothenate is phosphorylated [PANK1;3;4], Plasmodium falciparum" GO:0004595 : pantetheine-phosphate adenylyltransferase activity - xref: Reactome:REACT_89354 "Adenylation of phosphopantetheine, Mycobacterium tuberculosis" + xref: Reactome:REACT_113938 "Adenylation of phosphopantetheine, Plasmodium falciparum" GO:0004601 : peroxidase activity - xref: Reactome:REACT_107922 "Iodide is organified, Sus scrofa" + xref: Reactome:REACT_113904 "DIT and MIT combine to form triiodothyronine, Dictyostelium discoideum" + xref: Reactome:REACT_113988 "Two DITs combine to form thyroxine, Dictyostelium discoideum" + xref: Reactome:REACT_115058 "Two DITs combine to form thyroxine, Danio rerio" + xref: Reactome:REACT_114351 "Tyrosine is monoiodinated, Danio rerio" + xref: Reactome:REACT_97146 "Iodide is organified, Sus scrofa" + xref: Reactome:REACT_113235 "Tyrosine is diiodinated, Danio rerio" + xref: Reactome:REACT_111983 "Tyrosine is monoiodinated, Dictyostelium discoideum" + xref: Reactome:REACT_114100 "Iodide is organified, Dictyostelium discoideum" + xref: Reactome:REACT_112249 "Tyrosine is diiodinated, Dictyostelium discoideum" + xref: Reactome:REACT_112213 "Iodide is organified, Danio rerio" + xref: Reactome:REACT_114796 "DIT and MIT combine to form triiodothyronine, Danio rerio" GO:0004602 : glutathione peroxidase activity - xref: Reactome:REACT_94600 "2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O, Xenopus tropicalis" + xref: Reactome:REACT_114008 "2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O, Escherichia coli" + xref: Reactome:REACT_112920 "2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O, Danio rerio" + xref: Reactome:REACT_113573 "2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O, Plasmodium falciparum" GO:0004613 : phosphoenolpyruvate carboxykinase (GTP) activity - xref: Reactome:REACT_80888 "oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix], Gallus gallus" - xref: Reactome:REACT_95393 "oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix], Bos taurus" - xref: Reactome:REACT_84871 "oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [cytosol], Dictyostelium discoideum" + xref: Reactome:REACT_93986 "oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [cytosol], Dictyostelium discoideum" + xref: Reactome:REACT_77918 "oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix], Bos taurus" GO:0004614 : phosphoglucomutase activity - xref: Reactome:REACT_34003 "D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate, Caenorhabditis elegans" - xref: Reactome:REACT_93865 "alpha-D-Glucose 6-phosphate <=> D-Glucose 1-phosphate, Drosophila melanogaster" - xref: Reactome:REACT_109722 "alpha-D-Glucose 6-phosphate <=> D-Glucose 1-phosphate, Schizosaccharomyces pombe" - xref: Reactome:REACT_78351 "D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate, Drosophila melanogaster" - xref: Reactome:REACT_92124 "alpha-D-Glucose 6-phosphate <=> D-Glucose 1-phosphate, Staphylococcus aureus N315" - xref: Reactome:REACT_32221 "D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate, Staphylococcus aureus N315" - xref: Reactome:REACT_28185 "alpha-D-Glucose 6-phosphate <=> D-Glucose 1-phosphate, Saccharomyces cerevisiae" - xref: Reactome:REACT_94306 "alpha-D-Glucose 6-phosphate <=> D-Glucose 1-phosphate, Caenorhabditis elegans" - xref: Reactome:REACT_33235 "D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate, Dictyostelium discoideum" + xref: Reactome:REACT_85304 "alpha-D-Glucose 6-phosphate <=> D-Glucose 1-phosphate, Saccharomyces cerevisiae" + xref: Reactome:REACT_78611 "D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate, Dictyostelium discoideum" + xref: Reactome:REACT_107017 "alpha-D-Glucose 6-phosphate <=> D-Glucose 1-phosphate, Schizosaccharomyces pombe" GO:0004618 : phosphoglycerate kinase activity - xref: Reactome:REACT_93972 "1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ADP, Caenorhabditis elegans" - xref: Reactome:REACT_34152 "1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ADP, Escherichia coli" - xref: Reactome:REACT_80945 "ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate, Caenorhabditis elegans" - xref: Reactome:REACT_88265 "ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate, Escherichia coli" - xref: Reactome:REACT_101746 "1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ADP, Plasmodium falciparum" + xref: Reactome:REACT_114935 "1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ADP, Dictyostelium discoideum" + xref: Reactome:REACT_97790 "1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ADP, Plasmodium falciparum" + xref: Reactome:REACT_113751 "ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate, Dictyostelium discoideum" GO:0004619 : phosphoglycerate mutase activity - xref: Reactome:REACT_110401 "2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate, Taeniopygia guttata" - xref: Reactome:REACT_110510 "3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate, Taeniopygia guttata" + xref: Reactome:REACT_115206 "2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate, Dictyostelium discoideum" + xref: Reactome:REACT_112712 "3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate, Plasmodium falciparum" + xref: Reactome:REACT_114968 "3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate, Dictyostelium discoideum" + xref: Reactome:REACT_112969 "2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate, Escherichia coli" + xref: Reactome:REACT_111991 "2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate, Plasmodium falciparum" + xref: Reactome:REACT_115355 "3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate, Escherichia coli" GO:0004629 : phospholipase C activity + xref: Reactome:REACT_113587 "PLC gamma 2-mediated PIP2 hydrolysis, Saccharomyces cerevisiae" + xref: Reactome:REACT_112092 "PLC gamma 2-mediated PIP2 hydrolysis, Caenorhabditis elegans" + xref: Reactome:REACT_112637 "PLC gamma 2-mediated PIP2 hydrolysis, Drosophila melanogaster" + xref: Reactome:REACT_113114 "Hydrolysis of 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate by Activated Phospholipase C Beta-1, Dictyostelium discoideum" + xref: Reactome:REACT_115219 "PLC gamma 2-mediated PIP2 hydrolysis, Schizosaccharomyces pombe" + xref: Reactome:REACT_114743 "PLC gamma 2-mediated PIP2 hydrolysis, Oryza sativa" + xref: Reactome:REACT_112221 "Hydrolysis of 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate by Activated Phospholipase C Beta-1, Saccharomyces cerevisiae" + xref: Reactome:REACT_115019 "Hydrolysis of 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate by Activated Phospholipase C Beta-1, Schizosaccharomyces pombe" + xref: Reactome:REACT_112950 "PLC gamma 2-mediated PIP2 hydrolysis, Arabidopsis thaliana" + xref: Reactome:REACT_113364 "PLC gamma 2-mediated PIP2 hydrolysis, Dictyostelium discoideum" + xref: Reactome:REACT_113464 "PLC gamma 2-mediated PIP2 hydrolysis, Plasmodium falciparum" + xref: Reactome:REACT_114558 "Hydrolysis of 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate by Activated Phospholipase C Beta-1, Danio rerio" + xref: Reactome:REACT_112517 "PLC beta-mediated PIP2 hydrolysis, Saccharomyces cerevisiae" + xref: Reactome:REACT_112217 "PLC beta-mediated PIP2 hydrolysis, Schizosaccharomyces pombe" + xref: Reactome:REACT_112759 "PLC beta-mediated PIP2 hydrolysis, Dictyostelium discoideum" GO:0004632 : phosphopantothenate--cysteine ligase activity - xref: Reactome:REACT_87274 "Condensation of phosphopantothenate with cysteine, Dictyostelium discoideum" + xref: Reactome:REACT_112895 "Condensation of phosphopantothenate with cysteine, Oryza sativa" + xref: Reactome:REACT_113780 "Condensation of phosphopantothenate with cysteine, Arabidopsis thaliana" + xref: Reactome:REACT_108690 "Condensation of phosphopantothenate with cysteine, Dictyostelium discoideum" GO:0004634 : phosphopyruvate hydratase activity + xref: Reactome:REACT_112581 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O, Schizosaccharomyces pombe" + xref: Reactome:REACT_113501 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O, Oryza sativa" + xref: Reactome:REACT_114214 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O, Plasmodium falciparum" + xref: Reactome:REACT_114578 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O, Staphylococcus aureus N315" + xref: Reactome:REACT_113666 "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate, Escherichia coli" + xref: Reactome:REACT_112691 "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate, Saccharomyces cerevisiae" + xref: Reactome:REACT_115259 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O, Arabidopsis thaliana" + xref: Reactome:REACT_115437 "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate, Plasmodium falciparum" + xref: Reactome:REACT_112986 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O, Escherichia coli" + xref: Reactome:REACT_112925 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O, Mycobacterium tuberculosis" + xref: Reactome:REACT_113920 "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate, Oryza sativa" + xref: Reactome:REACT_114276 "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate, Schizosaccharomyces pombe" + xref: Reactome:REACT_112068 "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate, Mycobacterium tuberculosis" + xref: Reactome:REACT_115250 "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate, Staphylococcus aureus N315" + xref: Reactome:REACT_115184 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O, Dictyostelium discoideum" + xref: Reactome:REACT_113784 "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate, Arabidopsis thaliana" + xref: Reactome:REACT_113494 "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate, Dictyostelium discoideum" + xref: Reactome:REACT_112478 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O, Saccharomyces cerevisiae" GO:0004637 : phosphoribosylamine-glycine ligase activity - xref: Reactome:REACT_28515 "5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi, Caenorhabditis elegans" + xref: Reactome:REACT_93559 "5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi, Caenorhabditis elegans" GO:0004638 : phosphoribosylaminoimidazole carboxylase activity - xref: Reactome:REACT_97249 "AIR + CO2 => CAIR, Dictyostelium discoideum" GO:0004639 : phosphoribosylaminoimidazolesuccinocarboxamide synthase activity - xref: Reactome:REACT_89602 "CAIR + Aspartate + ATP => SAICAR + ADP + Pi, Dictyostelium discoideum" GO:0004642 : phosphoribosylformylglycinamidine synthase activity - xref: Reactome:REACT_34081 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Caenorhabditis elegans" - xref: Reactome:REACT_32434 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Staphylococcus aureus N315" - xref: Reactome:REACT_108004 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Mycobacterium tuberculosis" - xref: Reactome:REACT_110291 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Saccharomyces cerevisiae" - xref: Reactome:REACT_83796 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Oryza sativa" + xref: Reactome:REACT_112941 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Xenopus tropicalis" + xref: Reactome:REACT_108774 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Saccharomyces cerevisiae" + xref: Reactome:REACT_80793 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Caenorhabditis elegans" GO:0004643 : phosphoribosylaminoimidazolecarboxamide formyltransferase activity - xref: Reactome:REACT_108923 "AICAR + 10-Formyl-THF => FAICAR + THF, Dictyostelium discoideum" - xref: Reactome:REACT_83713 "AICAR + 10-Formyl-THF => FAICAR + THF, Caenorhabditis elegans" + xref: Reactome:REACT_98007 "AICAR + 10-Formyl-THF => FAICAR + THF, Dictyostelium discoideum" + xref: Reactome:REACT_96335 "AICAR + 10-Formyl-THF => FAICAR + THF, Caenorhabditis elegans" GO:0004650 : polygalacturonase activity - def: Catalysis of the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans. + def: Catalysis of the random hydrolysis of (1->4)-alpha-D-galactosiduronic linkages in pectate and other galacturonans. GO:0004652 : polynucleotide adenylyltransferase activity - xref: Reactome:REACT_101636 "mRNA polyadenylation, Rattus norvegicus" + xref: Reactome:REACT_111985 "mRNA polyadenylation, Arabidopsis thaliana" + xref: Reactome:REACT_113637 "mRNA polyadenylation, Oryza sativa" + xref: Reactome:REACT_113649 "mRNA polyadenylation, Drosophila melanogaster" + xref: Reactome:REACT_112181 "mRNA polyadenylation, Caenorhabditis elegans" GO:0004657 : proline dehydrogenase activity - xref: Reactome:REACT_102643 "proline => L-1-pyrroline-5-carboxylate, Saccharomyces cerevisiae" - xref: Reactome:REACT_103115 "proline => L-1-pyrroline-5-carboxylate, Schizosaccharomyces pombe" GO:0004666 : prostaglandin-endoperoxide synthase activity - xref: Reactome:REACT_101630 "Arachidonic acid oxidised to PGG2, Sus scrofa" - xref: Reactome:REACT_101694 "Arachidonic acid oxidised to PGG2, Bos taurus" + xref: Reactome:REACT_85880 "Arachidonic acid oxidised to PGG2, Bos taurus" + xref: Reactome:REACT_30504 "Arachidonic acid oxidised to PGG2, Sus scrofa" GO:0004672 : protein kinase activity - xref: Reactome:REACT_80082 "Phosphorylation and release of IRF3/IRF7, Sus scrofa" - xref: Reactome:REACT_6862 "Multiple IRAK1 autophosphorylation steps, Chlamydia trachomatis" - xref: Reactome:REACT_85508 "LKB1 phosphorylates the alpha subunit of AMPK heterotrimer, Saccharomyces cerevisiae" + xref: Reactome:REACT_114693 "Phosphorylation of pFADK1 by SRC, Xenopus tropicalis" + xref: Reactome:REACT_113334 "PKC phosphorylates GRK2, Caenorhabditis elegans" + xref: Reactome:REACT_6862 "Multiple IRAK1 autophosphorylation steps, Homo sapiens" + xref: Reactome:REACT_113821 "Activated Src activates ERK, Caenorhabditis elegans" + xref: Reactome:REACT_112267 "Autophosphorylation of FADK1 at Y397, Drosophila melanogaster" + xref: Reactome:REACT_112918 "Phosphorylation and activation of Ezrin, Caenorhabditis elegans" + xref: Reactome:REACT_111995 "Phosphorylation of p130Cas by SRC-FADK1 complex, Drosophila melanogaster" + xref: Reactome:REACT_114093 "LKB1 phosphorylates the alpha subunit of AMPK heterotrimer, Danio rerio" + xref: Reactome:REACT_113589 "Phosphorylation of pFADK1 by SRC, Drosophila melanogaster" + xref: Reactome:REACT_113440 "Phosphorylation and release of IRF3/IRF7, Xenopus tropicalis" + xref: Reactome:REACT_111075 "Phosphorylation of LIN52 component of MuvB by DYRK1A, Homo sapiens" + xref: Reactome:REACT_113100 "Activated Src activates ERK, Drosophila melanogaster" + xref: Reactome:REACT_88178 "Phosphorylation and release of IRF3/IRF7, Sus scrofa" GO:0004674 : protein serine/threonine kinase activity - synonym: "glycogen synthase a kinase activity" NARROW [EC:2.7.11.1] - xref: Reactome:REACT_102840 "MAPKAPK2 phosphorylates CREB at Serine 133, Drosophila melanogaster" - xref: Reactome:REACT_99441 "RSK1/2/3 phosphorylates CREB at Serine 133, Sus scrofa" - xref: Reactome:REACT_12485 "AKT can phosphorylate SRK, Homo sapiens" - xref: Reactome:REACT_29796 "Myosin regulatory light chain phosphorylation by ROCK, Sus scrofa" - xref: Reactome:REACT_100983 "PKA phosphorylates CREB, Drosophila melanogaster" - xref: Reactome:REACT_93573 "AKT can phosphorylate SRK, Caenorhabditis elegans" - xref: Reactome:REACT_100705 "AKT phosphorylates CREB, Drosophila melanogaster" - xref: Reactome:REACT_86248 "Myosin regulatory light chain phosphorylation by ROCK, Drosophila melanogaster" - xref: Reactome:REACT_96427 "AKT can phosphorylate SRK, Drosophila melanogaster" - xref: Reactome:REACT_106970 "AKT phosphorylates GSK3, Dictyostelium discoideum" - xref: Reactome:REACT_102500 "AKT can phosphorylate SRK, Rattus norvegicus" - xref: Reactome:REACT_85988 "Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9, Drosophila melanogaster" - xref: Reactome:REACT_91635 "MAP kinase activates MAPKAPK2, MAPKAPK3 and MSK1, Schizosaccharomyces pombe" - xref: Reactome:REACT_110094 "AKT can phosphorylate SRK, Taeniopygia guttata" - xref: Reactome:REACT_32495 "Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9, Sus scrofa" - xref: Reactome:REACT_25097 "IRAK4 autophosphorylation in the complex with activated TLR:MyD88:Mal, Chlamydia trachomatis" - xref: Reactome:REACT_6794 "Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal, Chlamydia trachomatis" - xref: Reactome:REACT_83305 "Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9, Drosophila melanogaster" - xref: Reactome:REACT_108483 "MAP kinase activates MAPKAPK2, MAPKAPK3 and MSK1, Saccharomyces cerevisiae" - xref: Reactome:REACT_87109 "Autophosphorylation of IRE1 dimer, Caenorhabditis elegans" - xref: Reactome:REACT_97853 "AKT can phosphorylate SRK, Mus musculus" - xref: Reactome:REACT_108115 "Phosphorylation of cofilin by LIMK-1, Bos taurus" - xref: Reactome:REACT_34471 "Transphosphorylation of pLIMK1, Drosophila melanogaster" - xref: Reactome:REACT_104657 "MSK1 activates ATF1, Drosophila melanogaster" - xref: Reactome:REACT_28277 "PDK1 phosphorylates AKT at T308, Dictyostelium discoideum" - xref: Reactome:REACT_82420 "Active p38 MAPK phosphorylates MAPKAPK2 or 3, Schizosaccharomyces pombe" - xref: Reactome:REACT_92752 "IRAK is activated, Sus scrofa" - xref: Reactome:REACT_84544 "First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9, Drosophila melanogaster" - xref: Reactome:REACT_6833 "First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal, Chlamydia trachomatis" - xref: Reactome:REACT_6973 "RIP1 facilitates IKK complex phosphorylation, Homo sapiens" - xref: Reactome:REACT_108360 "AKT phosphorylates GSK3, Caenorhabditis elegans" - xref: Reactome:REACT_94439 "monophospho-CERT + 2 ATP => multiphospho-CERT + 2 ADP, Xenopus tropicalis" - xref: Reactome:REACT_97916 "Transphosphorylation of pLIMK1, Bos taurus" - xref: Reactome:REACT_88834 "Inactivation of MEK1 by p34cdc2, Sus scrofa" - xref: Reactome:REACT_82094 "AKT can phosphorylate SRK, Canis familiaris" - xref: Reactome:REACT_84316 "Phosphorylation of Cdc25C at Ser 216 by Chk1, Danio rerio" - xref: Reactome:REACT_110258 "Active p38 MAPK phosphorylates MAPKAPK2 or 3, Saccharomyces cerevisiae" - xref: Reactome:REACT_34316 "Phosphorylation of cofilin by LIMK-1, Rattus norvegicus" - xref: Reactome:REACT_28491 "Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9, Sus scrofa" - xref: Reactome:REACT_110482 "AKT can phosphorylate SRK, Dictyostelium discoideum" - xref: Reactome:REACT_33772 "MSK1 activates CREB, Drosophila melanogaster" - xref: Reactome:REACT_34701 "AKT can phosphorylate SRK, Bos taurus" - xref: Reactome:REACT_96890 "RSK1/2/3 phosphorylates CREB at Serine 133, Drosophila melanogaster" - xref: Reactome:REACT_83130 "LIM kinase phosphorylation by ROCK, Bos taurus" - xref: Reactome:REACT_6728 "Phosphorylation of IRF-3/IRF7 and their release from the activated TLR4 complex, Chlamydia trachomatis" - xref: Reactome:REACT_92561 "Phosphorylation of PKC theta, Dictyostelium discoideum" - xref: Reactome:REACT_101144 "TORC2 (mTOR) phosphorylates AKT at S473, Dictyostelium discoideum" - xref: Reactome:REACT_96902 "MEK1 phosphorylates ERK-1, Saccharomyces cerevisiae" - xref: Reactome:REACT_93892 "hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP, Drosophila melanogaster" - xref: Reactome:REACT_81707 "First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9, Sus scrofa" - xref: Reactome:REACT_105863 "Phosphorylation of LIMK-1 by PAK, Bos taurus" + xref: Reactome:REACT_114782 "ERK1/2/5 activate RSK1/2/3, Dictyostelium discoideum" + xref: Reactome:REACT_115290 "p38MAPK phosphorylates MSK1, Oryza sativa" + xref: Reactome:REACT_115462 "Phosphorylation of Cdc25C at Ser 216 by Chk1, Caenorhabditis elegans" + xref: Reactome:REACT_112928 "Autophosphorylation of IRE1 dimer, Xenopus tropicalis" + xref: Reactome:REACT_112561 "AKT phosphorylates FOXO1A, Bos taurus" + xref: Reactome:REACT_113187 "ERK1/2 phosphorylates MSK1, Dictyostelium discoideum" + xref: Reactome:REACT_111131 "Type II Activin Receptor (ActRII/ACVR2) Phosphorylates Type I Activin Receptor (ActRIB/ACVR1B) in Response to NODAL, Homo sapiens" + xref: Reactome:REACT_113508 "AKT phosphorylates GSK3, Drosophila melanogaster" + xref: Reactome:REACT_114971 "Phosphorylation of MARCKS by Protein kinase C, alpha type, Drosophila melanogaster" + xref: Reactome:REACT_82465 "Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9, Sus scrofa" + xref: Reactome:REACT_113389 "AKT phosphorylates FOXO1A, Mus musculus" + xref: Reactome:REACT_113949 "p38MAPK phosphorylates MSK1, Schizosaccharomyces pombe" + xref: Reactome:REACT_115364 "CERT + ATP => monophospho-CERT + ADP, Drosophila melanogaster" + xref: Reactome:REACT_114835 "AKT can phosphorylate forkhead box transcription factors, Drosophila melanogaster" + xref: Reactome:REACT_111939 "Activated TAK1 mediates phosphorylation of the IKK Complex, Xenopus tropicalis" + xref: Reactome:REACT_113900 "CERT + ATP => monophospho-CERT + ADP, Caenorhabditis elegans" + xref: Reactome:REACT_113634 "Activated TAK1 mediates phosphorylation of the IKK Complex, Drosophila melanogaster" + xref: Reactome:REACT_112392 "AKT phosphorylates FOXO1A, Canis familiaris" + xref: Reactome:REACT_113764 "Phosphorylation of cofilin by LIMK-1, Danio rerio" + xref: Reactome:REACT_113486 "AKT phosphorylates TSC2, inhibiting it, Gallus gallus" + xref: Reactome:REACT_112965 "AKT can phosphorylate RSK, Saccharomyces cerevisiae" + xref: Reactome:REACT_112488 "Inactivation of MEK1 by p34cdc2, Schizosaccharomyces pombe" + xref: Reactome:REACT_112550 "AKT phosphorylates GSK3, Schizosaccharomyces pombe" + xref: Reactome:REACT_115293 "Phosphorylation of Cdc25C at Ser 216 by Chk1, Saccharomyces cerevisiae" + xref: Reactome:REACT_112501 "Phosphorylation of L1 by p90rsk, Saccharomyces cerevisiae" + xref: Reactome:REACT_111063 "SPRY2 is phosphorylated by phosphorylated MNK1, Homo sapiens" + xref: Reactome:REACT_6833 "First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal, Homo sapiens" + xref: Reactome:REACT_111117 "p-MEK phosphorylates ERK, Homo sapiens" + xref: Reactome:REACT_112393 "AKT phosphorylates p21Cip1 and p27Kip1, Gallus gallus" + xref: Reactome:REACT_115253 "p38MAPK phosphorylates MSK1, Xenopus tropicalis" + xref: Reactome:REACT_114718 "ERK1/2 activates ELK1, Caenorhabditis elegans" + xref: Reactome:REACT_114660 "ERK1/2 activates ELK1, Xenopus tropicalis" + xref: Reactome:REACT_115073 "TORC2 (mTOR) phosphorylates AKT at S473, Gallus gallus" + xref: Reactome:REACT_112505 "TORC2 (mTOR) phosphorylates AKT at S473, Schizosaccharomyces pombe" + xref: Reactome:REACT_113794 "Phospho-IKK Complex phosphorylates IkB within the IkB:NFkB Complex, Xenopus tropicalis" + xref: Reactome:REACT_111138 "Phosphorylation of R-SMAD2/3 by NODAL Receptor, Homo sapiens" + xref: Reactome:REACT_114306 "ERK1/2 phosphorylates MSK1, Arabidopsis thaliana" + xref: Reactome:REACT_113062 "CERT + ATP => monophospho-CERT + ADP, Sus scrofa" + xref: Reactome:REACT_79081 "Autophosphorylation of IRE1 dimer, Caenorhabditis elegans" + xref: Reactome:REACT_93998 "AKT can phosphorylate RSK, Caenorhabditis elegans" + xref: Reactome:REACT_87625 "First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9, Sus scrofa" + xref: Reactome:REACT_34701 "AKT can phosphorylate RSK, Bos taurus" + xref: Reactome:REACT_102500 "AKT can phosphorylate RSK, Rattus norvegicus" + xref: Reactome:REACT_115474 "AKT phosphorylates BAD, Xenopus tropicalis" + xref: Reactome:REACT_115340 "AKT phosphorylates FOXO1A, Gallus gallus" + xref: Reactome:REACT_112607 "AKT can phosphorylate RSK, Schizosaccharomyces pombe" + xref: Reactome:REACT_112321 "Phosphorylation of L1 by p90rsk, Schizosaccharomyces pombe" + xref: Reactome:REACT_113424 "PDK1 phosphorylates AKT at T308, Gallus gallus" + xref: Reactome:REACT_113560 "AKT interacts and phosphorylates Cot, Gallus gallus" + xref: Reactome:REACT_111058 "Phosphorylation of Smad2 by Nodal Receptor, Homo sapiens" + xref: Reactome:REACT_91830 "Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9, Sus scrofa" + xref: Reactome:REACT_96825 "IRAK is activated, Sus scrofa" + xref: Reactome:REACT_112514 "Activation of IKK complex, Xenopus tropicalis" + xref: Reactome:REACT_113835 "Transphosphorylation of pLIMK1, Taeniopygia guttata" + xref: Reactome:REACT_113744 "ERK1/2/5 activate RSK1/2/3, Schizosaccharomyces pombe" + xref: Reactome:REACT_113199 "Activation of NF-kB complex, Taeniopygia guttata" + xref: Reactome:REACT_113600 "Phosphorylation of PKC theta, Schizosaccharomyces pombe" + xref: Reactome:REACT_112107 "AKT phosphorylates caspase-9, Gallus gallus" + xref: Reactome:REACT_113619 "PDK1 phosphorylates AKT at T308, Saccharomyces cerevisiae" + xref: Reactome:REACT_113549 "ERK1/2/5 activate RSK1/2/3, Oryza sativa" + xref: Reactome:REACT_6728 "Phosphorylation of IRF-3/IRF7 and their release from the activated TLR4 complex, Homo sapiens" + xref: Reactome:REACT_113006 "ERK1/2 phosphorylates MSK1, Oryza sativa" + xref: Reactome:REACT_113693 "MEK1 phosphorylates ERK-1, Oryza sativa" + xref: Reactome:REACT_114476 "p38MAPK phosphorylates MSK1, Dictyostelium discoideum" + xref: Reactome:REACT_113719 "ERK1/2 phosphorylates MSK1, Schizosaccharomyces pombe" + xref: Reactome:REACT_114044 "Autophosphorylation of IRE1 dimer, Oryza sativa" + xref: Reactome:REACT_113575 "MEK1 phosphorylates ERK-1, Arabidopsis thaliana" + xref: Reactome:REACT_112583 "AKT phosphorylates GSK3, Gallus gallus" + xref: Reactome:REACT_113732 "p38MAPK phosphorylates MSK1, Arabidopsis thaliana" + xref: Reactome:REACT_114650 "ERK1/2 phosphorylates MSK1, Xenopus tropicalis" + xref: Reactome:REACT_115391 "ERK1/2/5 activate RSK1/2/3, Arabidopsis thaliana" + xref: Reactome:REACT_110094 "AKT can phosphorylate RSK, Taeniopygia guttata" + xref: Reactome:REACT_112061 "Phosphorylation of Cdc25C at Ser 216 by Chk1, Schizosaccharomyces pombe" + xref: Reactome:REACT_111130 "Type II Activin Receptor (ActRIIB/ACVR2B) Phosphorylates Type I Activin Receptor (ActRIC/ACVR1C) in Response to NODAL, Homo sapiens" + xref: Reactome:REACT_6794 "Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal, Homo sapiens" + xref: Reactome:REACT_97853 "AKT can phosphorylate RSK, Mus musculus" + xref: Reactome:REACT_111068 "ACVR2A/B (ActRIIA/B) Phosphorylates ACVR1B (ActRIB, ALK4) in Response to Activin, Homo sapiens" + xref: Reactome:REACT_113717 "AKT can phosphorylate NUR77, Drosophila melanogaster" + xref: Reactome:REACT_113810 "Phosphorylation of Bcl10, Xenopus tropicalis" + xref: Reactome:REACT_114899 "MSK1 activates ATF1, Xenopus tropicalis" + xref: Reactome:REACT_96427 "AKT can phosphorylate RSK, Drosophila melanogaster" + xref: Reactome:REACT_114479 "AKT can phosphorylate NUR77, Caenorhabditis elegans" + xref: Reactome:REACT_114136 "hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP, Caenorhabditis elegans" + xref: Reactome:REACT_112404 "Inactivation of MEK1 by p34cdc2, Saccharomyces cerevisiae" + xref: Reactome:REACT_114322 "AKT phosphorylates FOXO1A, Rattus norvegicus" + xref: Reactome:REACT_113830 "MEK1 phosphorylates ERK-1, Dictyostelium discoideum" + xref: Reactome:REACT_113045 "AKT phosphorylates FOXO1A, Drosophila melanogaster" + xref: Reactome:REACT_25097 "IRAK4 autophosphorylation in the complex with activated TLR:MyD88:Mal, Homo sapiens" + xref: Reactome:REACT_114321 "AKT phosphorylates IKKalpha, Gallus gallus" + xref: Reactome:REACT_34104 "RSK1/2/3 phosphorylates CREB at Serine 133, Sus scrofa" + xref: Reactome:REACT_113059 "Autophosphorylation of IRE1 dimer, Dictyostelium discoideum" + xref: Reactome:REACT_113729 "AKT phosphorylates TSC2, inhibiting it, Schizosaccharomyces pombe" + xref: Reactome:REACT_114092 "AKT phosphorylates CREB, Gallus gallus" + xref: Reactome:REACT_111196 "PKC alpha interacts with and phosphorylates KIT, Homo sapiens" + xref: Reactome:REACT_114548 "AKT phosphorylates MDM2, Gallus gallus" + xref: Reactome:REACT_114335 "MSK1 activates CREB, Xenopus tropicalis" + xref: Reactome:REACT_102053 "MEK1 phosphorylates ERK-1, Saccharomyces cerevisiae" + xref: Reactome:REACT_111972 "Autophosphorylation of IRE1 dimer, Arabidopsis thaliana" + xref: Reactome:REACT_114581 "AKT can phosphorylate forkhead box transcription factors, Gallus gallus" + xref: Reactome:REACT_112516 "TORC2 (mTOR) phosphorylates AKT at S473, Saccharomyces cerevisiae" + xref: Reactome:REACT_12485 "AKT can phosphorylate RSK, Homo sapiens" + xref: Reactome:REACT_113479 "ERK1/2 activates ELK1, Taeniopygia guttata" + xref: Reactome:REACT_112003 "Phosphorylation of PKC theta, Saccharomyces cerevisiae" + xref: Reactome:REACT_112628 "AKT phosphorylates FOXO1A, Taeniopygia guttata" + xref: Reactome:REACT_114079 "PDK1 phosphorylates AKT at T308, Schizosaccharomyces pombe" + xref: Reactome:REACT_82094 "AKT can phosphorylate RSK, Canis familiaris" GO:0004675 : transmembrane receptor protein serine/threonine kinase activity - xref: Reactome:REACT_106768 "Activated type I receptor phosphorylates R-SMAD directly, Canis familiaris" - xref: Reactome:REACT_6879 "Activated type I receptor phosphorylates R-SMAD directly, Homo sapiens" - xref: Reactome:REACT_80118 "Activated type I receptor phosphorylates R-SMAD directly, Bos taurus" - xref: Reactome:REACT_30655 "Activated type I receptor phosphorylates R-SMAD directly, Mus musculus" - xref: Reactome:REACT_80791 "Activated type I receptor phosphorylates R-SMAD directly, Gallus gallus" - xref: Reactome:REACT_31200 "Activated type I receptor phosphorylates R-SMAD directly, Rattus norvegicus" - xref: Reactome:REACT_31836 "Activated type I receptor phosphorylates R-SMAD directly, Danio rerio" - xref: Reactome:REACT_77790 "Activated type I receptor phosphorylates R-SMAD directly, Taeniopygia guttata" - xref: Reactome:REACT_81763 "Activated type I receptor phosphorylates R-SMAD directly, Sus scrofa" - xref: Reactome:REACT_31960 "Activated type I receptor phosphorylates R-SMAD directly, Xenopus tropicalis" + xref: Reactome:REACT_31960 "Activated type I receptor phosphorylates SMAD2/3 directly, Xenopus tropicalis" + xref: Reactome:REACT_81763 "Activated type I receptor phosphorylates SMAD2/3 directly, Sus scrofa" + xref: Reactome:REACT_114102 "Activated type I receptor phosphorylates SMAD2/3 directly, Drosophila melanogaster" + xref: Reactome:REACT_31836 "Activated type I receptor phosphorylates SMAD2/3 directly, Danio rerio" + xref: Reactome:REACT_106768 "Activated type I receptor phosphorylates SMAD2/3 directly, Canis familiaris" + xref: Reactome:REACT_30655 "Activated type I receptor phosphorylates SMAD2/3 directly, Mus musculus" + xref: Reactome:REACT_80118 "Activated type I receptor phosphorylates SMAD2/3 directly, Bos taurus" + xref: Reactome:REACT_6879 "Activated type I receptor phosphorylates SMAD2/3 directly, Homo sapiens" + xref: Reactome:REACT_77790 "Activated type I receptor phosphorylates SMAD2/3 directly, Taeniopygia guttata" + xref: Reactome:REACT_80791 "Activated type I receptor phosphorylates SMAD2/3 directly, Gallus gallus" + xref: Reactome:REACT_31200 "Activated type I receptor phosphorylates SMAD2/3 directly, Rattus norvegicus" GO:0004676 : 3-phosphoinositide-dependent protein kinase activity - xref: Reactome:REACT_29542 "PDK1 activates PKC zeta, Caenorhabditis elegans" - xref: Reactome:REACT_104844 "PDK1 activates PKC zeta, Dictyostelium discoideum" + xref: Reactome:REACT_112574 "PDK1 activates PKC zeta, Schizosaccharomyces pombe" + xref: Reactome:REACT_112723 "PDK1 activates PKC zeta, Gallus gallus" + xref: Reactome:REACT_115114 "PDK1 activates PKC zeta, Saccharomyces cerevisiae" GO:0004679 : AMP-activated protein kinase activity - xref: Reactome:REACT_101245 "Phosphorylation of ChREBP at Serine 568 by AMPK, Caenorhabditis elegans" - xref: Reactome:REACT_79108 "pAMPK inactivates ACC2 inhibiting malonyl-CoA synthesis, Caenorhabditis elegans" + xref: Reactome:REACT_114056 "pAMPK inactivates ACC2 inhibiting malonyl-CoA synthesis, Danio rerio" + xref: Reactome:REACT_113551 "Phosphorylation of ChREBP at Serine 568 by AMPK, Danio rerio" + xref: Reactome:REACT_115260 "pAMPK inactivates ACC2 inhibiting malonyl-CoA synthesis, Taeniopygia guttata" + xref: Reactome:REACT_115507 "Phosphorylation of ChREBP at Serine 568 by AMPK, Xenopus tropicalis" GO:0004683 : calmodulin-dependent protein kinase activity + xref: Reactome:REACT_113927 "CaMK IV phosphorylates CREB, Xenopus tropicalis" + xref: Reactome:REACT_114360 "CaMK IV autophosphorylation, Dictyostelium discoideum" + xref: Reactome:REACT_112694 "CaMK IV autophosphorylation, Xenopus tropicalis" GO:0004689 : phosphorylase kinase activity - synonym: "phosphorylase b kinase activity" EXACT [EC:2.7.11.19] + xref: Reactome:REACT_113997 "glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP, Drosophila melanogaster" + xref: Reactome:REACT_112850 "glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP, Danio rerio" + xref: Reactome:REACT_114606 "glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP, Xenopus tropicalis" GO:0004691 : cAMP-dependent protein kinase activity - xref: Reactome:REACT_87995 "PKA phosphorylates PDE4B, Drosophila melanogaster" - xref: Reactome:REACT_88070 "Phosphorylation of PF2K-Pase by PKA catalytic subunit, Schizosaccharomyces pombe" - xref: Reactome:REACT_92457 "Phosphorylation of PF2K-Pase by PKA catalytic subunit, Drosophila melanogaster" - xref: Reactome:REACT_23999 "The common beta chain is phosphorylated on Ser-585, Homo sapiens" - xref: Reactome:REACT_80893 "Phosphorylation of PF2K-Pase by PKA catalytic subunit, Saccharomyces cerevisiae" + xref: Reactome:REACT_108468 "Phosphorylation of PF2K-Pase by PKA catalytic subunit, Schizosaccharomyces pombe" + xref: Reactome:REACT_115301 "PKA phosphorylates PDE4B, Dictyostelium discoideum" + xref: Reactome:REACT_112611 "Phosphorylation of pChREBP (Thr 666) at Ser(196) by PKA, Xenopus tropicalis" + xref: Reactome:REACT_114883 "PKA phosphorylates PDE4B, Plasmodium falciparum" + xref: Reactome:REACT_94203 "Phosphorylation of PF2K-Pase by PKA catalytic subunit, Saccharomyces cerevisiae" + xref: Reactome:REACT_112409 "Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA), Xenopus tropicalis" + xref: Reactome:REACT_23999 "IL3RB is phosphorylated on Ser-585, Homo sapiens" + xref: Reactome:REACT_113680 "Phosphorylation of PF2K-Pase by PKA catalytic subunit, Gallus gallus" + xref: Reactome:REACT_115177 "PKA phosphorylates PDE4B, Caenorhabditis elegans" + xref: Reactome:REACT_112372 "Phosphorylation of ChREBP at Thr(666) by PKA, Xenopus tropicalis" + xref: Reactome:REACT_114719 "PKA phosphorylates DARPP-32 on Thr34, Xenopus tropicalis" GO:0004692 : cGMP-dependent protein kinase activity + xref: Reactome:REACT_111245 "PTPS is phosphorylated by cGMP-dependant protein kinase II, Homo sapiens" + xref: Reactome:REACT_111129 "Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II, Homo sapiens" + xref: Reactome:REACT_114536 "PKG1 phosphorylates IRAG:IP3R1 inhibiting IP3-stimulated Ca2+ release, Xenopus tropicalis" GO:0004693 : cyclin-dependent protein kinase activity - xref: Reactome:REACT_79948 "Phosphorylation of Cdh1 by Cyclin B1:Cdc2, Caenorhabditis elegans" - xref: Reactome:REACT_104569 "Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160), Drosophila melanogaster" - xref: Reactome:REACT_82588 "Phosphorylation of M phase proteins by active Cyclin B1:Cdc2 complexes, Caenorhabditis elegans" - xref: Reactome:REACT_85295 "Cyclin E:Cdk2-mediated phosphorylation of Rb, Sus scrofa" + xref: Reactome:REACT_112082 "Cyclin D:Cdk4/6 mediated phosphorylation of Rb and dissociation of phospho-Rb from the E2F1/2/3:DP-1 complexes, Xenopus tropicalis" + xref: Reactome:REACT_111206 "Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex, Homo sapiens" + xref: Reactome:REACT_113866 "Phosphorylation of M phase proteins by active Cyclin B1:Cdc2 complexes, Schizosaccharomyces pombe" + xref: Reactome:REACT_115457 "Phosphorylation of M phase proteins by active Cyclin B1:Cdc2 complexes, Saccharomyces cerevisiae" + xref: Reactome:REACT_91084 "Cyclin E:Cdk2-mediated phosphorylation of Rb, Sus scrofa" + xref: Reactome:REACT_115193 "CDK5 phosphorylates DARPP-32 on Thr75, Xenopus tropicalis" + xref: Reactome:REACT_112868 "Cyclin B/Cdk1 mediate phosphorylation of NuMA, Xenopus tropicalis" + xref: Reactome:REACT_111248 "Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex, Homo sapiens" + xref: Reactome:REACT_113042 "Phosphorylation of Cdh1 by Cyclin B1:Cdc2, Saccharomyces cerevisiae" + xref: Reactome:REACT_113808 "Phosphorylation of Cdh1 by Cyclin B1:Cdc2, Schizosaccharomyces pombe" + xref: Reactome:REACT_113645 "Cyclin E:Cdk2-mediated phosphorylation of Rb, Xenopus tropicalis" GO:0004697 : protein kinase C activity - xref: Reactome:REACT_91630 "DAG stimulates protein kinase C-delta, Sus scrofa" - xref: Reactome:REACT_105020 "DAG stimulates protein kinase C-delta, Dictyostelium discoideum" + xref: Reactome:REACT_28264 "DAG stimulates protein kinase C-delta, Sus scrofa" + xref: Reactome:REACT_113684 "DAG stimulates protein kinase C-delta, Schizosaccharomyces pombe" + xref: Reactome:REACT_113213 "DAG stimulates protein kinase C-delta, Saccharomyces cerevisiae" GO:0004698 : calcium-dependent protein kinase C activity - xref: Reactome:REACT_32031 "Phosphorylation of Platelet Sec-1, Dictyostelium discoideum" - xref: Reactome:REACT_91722 "Phosphorylation of Syntaxin-4, Dictyostelium discoideum" + xref: Reactome:REACT_112603 "Phosphorylation of Platelet Sec-1, Schizosaccharomyces pombe" + xref: Reactome:REACT_111980 "Phosphorylation of Syntaxin-4, Schizosaccharomyces pombe" + xref: Reactome:REACT_113338 "Phosphorylation of Platelet Sec-1, Saccharomyces cerevisiae" + xref: Reactome:REACT_112939 "Endocytosis of Ca impermeable AMPA receptors, Xenopus tropicalis" + xref: Reactome:REACT_115137 "Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites, Xenopus tropicalis" + xref: Reactome:REACT_111973 "Phosphorylation of Syntaxin-4, Saccharomyces cerevisiae" GO:0004705 : JUN kinase activity + xref: Reactome:REACT_113885 "JNK phosphorylates BIM, BAD and other targets, Xenopus tropicalis" GO:0004707 : MAP kinase activity - xref: Reactome:REACT_83486 "Activation of p38MAPK by DSCAM, Drosophila melanogaster" + xref: Reactome:REACT_115393 "Phosphorylation of UBF-1:rDNA Promoter, Rattus norvegicus" + xref: Reactome:REACT_111161 "Activated ERK1/2 threonine-phosphorylate FRS2alpha., Homo sapiens" GO:0004709 : MAP kinase kinase kinase activity + xref: Reactome:REACT_114785 "Akt:pCot phosphorylates NIK, Gallus gallus" GO:0004712 : protein serine/threonine/tyrosine kinase activity - xref: Reactome:REACT_106337 "activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3, Schizosaccharomyces pombe" - xref: Reactome:REACT_95515 "activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3, Saccharomyces cerevisiae" GO:0004713 : protein tyrosine kinase activity - xref: Reactome:REACT_94150 "Phosphorylation of Unc5C, Taeniopygia guttata" - xref: Reactome:REACT_77187 "Phosphorylation of Cbl (EGFR:Cbl:Grb2), Rattus norvegicus" - xref: Reactome:REACT_28594 "Autophosphorylation of PDGF alpha receptors, Drosophila melanogaster" - xref: Reactome:REACT_34631 "Phosphorylation of Cbl (EGFR:Cbl), Mus musculus" - xref: Reactome:REACT_107024 "Activation of Vav1, Sus scrofa" - xref: Reactome:REACT_21344 "SHC becomes phosphorylated, Homo sapiens" - xref: Reactome:REACT_90842 "Phosphorylation of L1 by EPHB2, Caenorhabditis elegans" - xref: Reactome:REACT_91362 "Inactivation of Lck by Csk, Sus scrofa" - xref: Reactome:REACT_84824 "Phosphorylation of Cbl (EGFR:Cbl:Grb2), Gallus gallus" - xref: Reactome:REACT_12424 "Phosphorylation of Cbl (EGFR:Cbl), Homo sapiens" - xref: Reactome:REACT_97992 "SEMA4D interacts with Plexin-B1:ErbB2, Bos taurus" - xref: Reactome:REACT_29482 "Activation of Lck, Sus scrofa" - xref: Reactome:REACT_108276 "SHC becomes phosphorylated, Mus musculus" - xref: Reactome:REACT_85443 "Phosphorylation of Cbl (EGFR:Cbl:Grb2), Taeniopygia guttata" - xref: Reactome:REACT_87034 "SHC becomes phosphorylated, Canis familiaris" - xref: Reactome:REACT_109237 "Phosphorylation of Cbl (EGFR:Cbl:Grb2), Mus musculus" - xref: Reactome:REACT_81472 "SHC becomes phosphorylated, Xenopus tropicalis" - xref: Reactome:REACT_31634 "Phosphorylation of Cbl (EGFR:Cbl:Grb2), Danio rerio" - xref: Reactome:REACT_33766 "SHC becomes phosphorylated, Taeniopygia guttata" - xref: Reactome:REACT_81025 "SHC becomes phosphorylated, Rattus norvegicus" - xref: Reactome:REACT_106096 "SHC becomes phosphorylated, Gallus gallus" - xref: Reactome:REACT_12491 "Phosphorylation of Cbl (EGFR:Cbl:Grb2), Homo sapiens" - xref: Reactome:REACT_106379 "Phosphorylation of Cbl (EGFR:Cbl), Xenopus tropicalis" - xref: Reactome:REACT_79877 "Autophosphorylation of PDGF alpha/beta receptors, Drosophila melanogaster" - xref: Reactome:REACT_86510 "Phosphorylation of Cbl (EGFR:Cbl), Canis familiaris" - xref: Reactome:REACT_30339 "Autophosphorylation of PDGF beta receptors, Drosophila melanogaster" - xref: Reactome:REACT_94045 "SHC becomes phosphorylated, Sus scrofa" - xref: Reactome:REACT_83830 "SHC becomes phosphorylated, Danio rerio" - xref: Reactome:REACT_82597 "Phosphorylation of Cbl (EGFR:Cbl:Grb2), Xenopus tropicalis" - xref: Reactome:REACT_94384 "Phosphorylation of Cbl (EGFR:Cbl), Danio rerio" - xref: Reactome:REACT_78499 "Change of PKC theta conformation, Sus scrofa" - xref: Reactome:REACT_84931 "Phosphorylation of nephrin by the Src family kinase Fyn, Bos taurus" - xref: Reactome:REACT_97562 "Phosphorylation of Cbl (EGFR:Cbl), Rattus norvegicus" - xref: Reactome:REACT_105313 "Activation of Src, Bos taurus" - xref: Reactome:REACT_93370 "Recruitment of FAK to NCAM1:Fyn in lipid rafts, Caenorhabditis elegans" - xref: Reactome:REACT_95250 "Activation of ZAP-70, Sus scrofa" - xref: Reactome:REACT_88609 "Phosphorylation of SLP-76, Sus scrofa" - xref: Reactome:REACT_88507 "Phosphorylation of ZAP-70 by Lck, Sus scrofa" - xref: Reactome:REACT_107486 "Phosphorylation of ITAM motifs in CD3 complexes, Sus scrofa" - xref: Reactome:REACT_89762 "Phosphorylation of Cbl (EGFR:Cbl:Grb2), Canis familiaris" - xref: Reactome:REACT_90342 "Phosphorylation of Cbl (EGFR:Cbl), Taeniopygia guttata" - xref: Reactome:REACT_34183 "Phosphorylation of DCC by Fyn, Taeniopygia guttata" - xref: Reactome:REACT_32619 "Phosphorylation of TBSMs in LAT, Sus scrofa" - xref: Reactome:REACT_99315 "SHC becomes phosphorylated, Bos taurus" - xref: Reactome:REACT_87633 "Phosphorylation of L1 by EPHB2, Drosophila melanogaster" - xref: Reactome:REACT_29123 "Phosphorylation of Cbl (EGFR:Cbl:Grb2), Bos taurus" + xref: Reactome:REACT_112967 "Phosphorylation of APS, Canis familiaris" + xref: Reactome:REACT_114996 "Autophosphorylation of NCAM1 bound Fyn, Drosophila melanogaster" + xref: Reactome:REACT_113474 "Autophosphorylation of KIT, Gallus gallus" + xref: Reactome:REACT_114870 "Phosphorylation of FRS2-beta by activated FGFR, Rattus norvegicus" + xref: Reactome:REACT_114045 "Autocatalytic phosphorylation of FGFR1b, Caenorhabditis elegans" + xref: Reactome:REACT_114111 "Phosphorylation of Unc5C, Drosophila melanogaster" + xref: Reactome:REACT_111134 "Phosphorylation of PLCgamma by PDGFR, Homo sapiens" + xref: Reactome:REACT_112269 "Phosphorylation of L1 by SRC, Drosophila melanogaster" + xref: Reactome:REACT_113759 "Phosphorylation of ITIM in SIRP alpha, Taeniopygia guttata" + xref: Reactome:REACT_34631 "Phosphorylation of CBL (EGFR:CBL), Mus musculus" + xref: Reactome:REACT_113709 "Phosphorylation of CD28, Xenopus tropicalis" + xref: Reactome:REACT_112047 "Phosphorylation of Unc5C, Gallus gallus" + xref: Reactome:REACT_106379 "Phosphorylation of CBL (EGFR:CBL), Xenopus tropicalis" + xref: Reactome:REACT_113828 "Autophosphorylation of PDGF beta receptors, Xenopus tropicalis" + xref: Reactome:REACT_112044 "Autocatalytic phosphorylation of FGFR2b, Caenorhabditis elegans" + xref: Reactome:REACT_111070 "Phosphorylation of JAK2, Homo sapiens" + xref: Reactome:REACT_111218 "STAT5 tyrosine phosphorylation, Homo sapiens" + xref: Reactome:REACT_111244 "Phosphorylation of STATs, Homo sapiens" + xref: Reactome:REACT_31634 "Phosphorylation of CBL (EGFR:GRB2:CBL), Danio rerio" + xref: Reactome:REACT_114167 "Phosphorylation of APS, Danio rerio" + xref: Reactome:REACT_113122 "Autocatalytic phosphorylation of FGFR1c, Caenorhabditis elegans" + xref: Reactome:REACT_112193 "Autophosphorylation of KIT, Rattus norvegicus" + xref: Reactome:REACT_114129 "Phosphorylation of FRS2-alpha by activated FGFR, Caenorhabditis elegans" + xref: Reactome:REACT_113016 "Phosphorylation of FRS2-beta by activated FGFR, Gallus gallus" + xref: Reactome:REACT_114569 "Phosphorylation of ITIM in SIRP alpha, Bos taurus" + xref: Reactome:REACT_112170 "Binding and activation of MAP Kinase, Oryza sativa" + xref: Reactome:REACT_112027 "Autophosphorylation of KIT, Xenopus tropicalis" + xref: Reactome:REACT_114895 "Activation of SRC by Ral-GTP, Drosophila melanogaster" + xref: Reactome:REACT_109237 "Phosphorylation of CBL (EGFR:GRB2:CBL), Mus musculus" + xref: Reactome:REACT_113738 "Autophosphorylation of KIT, Sus scrofa" + xref: Reactome:REACT_115017 "Phosphorylation of FRS2-beta by activated FGFR, Taeniopygia guttata" + xref: Reactome:REACT_84824 "Phosphorylation of CBL (EGFR:GRB2:CBL), Gallus gallus" + xref: Reactome:REACT_113138 "Phosphorylation of FRS2-beta by activated FGFR, Caenorhabditis elegans" + xref: Reactome:REACT_114530 "Phosphorylation of FRS2-beta by activated FGFR, Xenopus tropicalis" + xref: Reactome:REACT_113884 "Phosphorylation of APS, Sus scrofa" + xref: Reactome:REACT_115375 "Autocatalytic phosphorylation of FGFR1b, Drosophila melanogaster" + xref: Reactome:REACT_114600 "Binding and activation of MAP Kinase, Dictyostelium discoideum" + xref: Reactome:REACT_111072 "Phosphorylation and activation of VAV1, Homo sapiens" + xref: Reactome:REACT_112349 "SYK activation by SRC, Drosophila melanogaster" + xref: Reactome:REACT_113655 "Autophosphorylation of KIT, Mus musculus" + xref: Reactome:REACT_114124 "Phosphorylation of PLC-gamma1, Xenopus tropicalis" + xref: Reactome:REACT_115402 "Phosphorylation of FRS2-beta by activated FGFR, Sus scrofa" + xref: Reactome:REACT_113262 "Phosphorylation of APS, Xenopus tropicalis" + xref: Reactome:REACT_111096 "SRC phosphorylates SPRY2 on Y55 and Y227, Homo sapiens" + xref: Reactome:REACT_115068 "Phosphorylation of ITIM in SIRP alpha, Gallus gallus" + xref: Reactome:REACT_115067 "Autocatalytic phosphorylation of FGFR2c, Caenorhabditis elegans" + xref: Reactome:REACT_12491 "Phosphorylation of CBL (EGFR:GRB2:CBL), Homo sapiens" + xref: Reactome:REACT_114640 "Phosphorylation of APS, Taeniopygia guttata" + xref: Reactome:REACT_113409 "Autophosphorylation of KIT, Canis familiaris" + xref: Reactome:REACT_111112 "Phosphorylation of APS, Homo sapiens" + xref: Reactome:REACT_115305 "Phosphorylation of DCC by Fyn, Gallus gallus" + xref: Reactome:REACT_114997 "Phosphorylation and activation of VAV1, Sus scrofa" + xref: Reactome:REACT_113647 "Autophosphorylation of KIT, Taeniopygia guttata" + xref: Reactome:REACT_111958 "Phosphorylation of APS, Rattus norvegicus" + xref: Reactome:REACT_111201 "Phosphorylation of FRS2-beta by activated FGFR, Homo sapiens" + xref: Reactome:REACT_112071 "Phosphorylation and activation of VAV1, Canis familiaris" + xref: Reactome:REACT_113384 "Autophosphorylation of SRC, Xenopus tropicalis" + xref: Reactome:REACT_112962 "Phosphorylation of APS, Bos taurus" + xref: Reactome:REACT_112299 "PLC gamma phosphorylation by FGFR, Drosophila melanogaster" + xref: Reactome:REACT_114702 "Autocatalytic phosphorylation of FGFR3b, Caenorhabditis elegans" + xref: Reactome:REACT_112411 "PLC gamma phosphorylation by FGFR, Caenorhabditis elegans" + xref: Reactome:REACT_115354 "Phosphorylation of FRS2-beta by activated FGFR, Bos taurus" + xref: Reactome:REACT_115514 "Phosphorylation of Unc5C, Caenorhabditis elegans" + xref: Reactome:REACT_115469 "Autophosphorylation of SRC, Drosophila melanogaster" + xref: Reactome:REACT_113363 "Phosphorylation of nephrin by the Src family kinase Fyn, Xenopus tropicalis" + xref: Reactome:REACT_77187 "Phosphorylation of CBL (EGFR:GRB2:CBL), Rattus norvegicus" + xref: Reactome:REACT_113366 "Phosphorylation of nephrin by the Src family kinase Fyn, Caenorhabditis elegans" + xref: Reactome:REACT_112582 "Phosphorylation of FRS2-beta by activated FGFR, Drosophila melanogaster" + xref: Reactome:REACT_114674 "Autophosphorylation of KIT, Bos taurus" + xref: Reactome:REACT_113678 "SHP2 is phosphorylated by activated FGFR, Caenorhabditis elegans" + xref: Reactome:REACT_114856 "Phosphorylation of FRS2-beta by activated FGFR, Danio rerio" + xref: Reactome:REACT_114781 "Binding and activation of MAP Kinase, Arabidopsis thaliana" + xref: Reactome:REACT_113307 "Phosphorylation and activation of VAV1, Bos taurus" + xref: Reactome:REACT_33942 "Activation of Src, Bos taurus" + xref: Reactome:REACT_29123 "Phosphorylation of CBL (EGFR:GRB2:CBL), Bos taurus" + xref: Reactome:REACT_113630 "Phosphorylation and activation of VAV1, Xenopus tropicalis" + xref: Reactome:REACT_85443 "Phosphorylation of CBL (EGFR:GRB2:CBL), Taeniopygia guttata" + xref: Reactome:REACT_113502 "Phosphorylation of FAK by Src kinase, Drosophila melanogaster" + xref: Reactome:REACT_111110 "SHC1 is phosphorylated, Homo sapiens" + xref: Reactome:REACT_89762 "Phosphorylation of CBL (EGFR:GRB2:CBL), Canis familiaris" + xref: Reactome:REACT_12424 "Phosphorylation of CBL (EGFR:CBL), Homo sapiens" + xref: Reactome:REACT_113926 "Phosphorylation of APS, Mus musculus" + xref: Reactome:REACT_114185 "Phosphorylation of nephrin by the Src family kinase Fyn, Drosophila melanogaster" + xref: Reactome:REACT_115418 "Autocatalytic phosphorylation of FGFR2b, Drosophila melanogaster" + xref: Reactome:REACT_82597 "Phosphorylation of CBL (EGFR:GRB2:CBL), Xenopus tropicalis" + xref: Reactome:REACT_114012 "Phosphorylation of FRS2-beta by activated FGFR, Canis familiaris" + xref: Reactome:REACT_114786 "Autophosphorylation of KIT, Danio rerio" + xref: Reactome:REACT_113861 "Phosphorylation of APS, Gallus gallus" + xref: Reactome:REACT_112362 "Phosphorylation of FADK1, Xenopus tropicalis" + xref: Reactome:REACT_113605 "Phosphorylation and activation of VAV1, Mus musculus" + xref: Reactome:REACT_111147 "JAK2 phosphorylation of GHR, Homo sapiens" + xref: Reactome:REACT_111246 "Autocatalytic phosphorylation of BetaKlotho-bound FGFR4, Homo sapiens" + xref: Reactome:REACT_90301 "SEMA4D interacts with Plexin-B1:ErbB2, Bos taurus" + xref: Reactome:REACT_113372 "Phosphorylation of L1 by SRC, Caenorhabditis elegans" + xref: Reactome:REACT_100038 "Phosphorylation of nephrin by the Src family kinase Fyn, Bos taurus" + xref: Reactome:REACT_111152 "Phosphorylation of SHP2 by SFKs, Homo sapiens" + xref: Reactome:REACT_94384 "Phosphorylation of CBL (EGFR:CBL), Danio rerio" + xref: Reactome:REACT_114914 "Phosphorylation of FRS2-beta by activated FGFR, Mus musculus" + xref: Reactome:REACT_112557 "Autocatalytic phosphorylation of FGFR4, Caenorhabditis elegans" + xref: Reactome:REACT_86510 "Phosphorylation of CBL (EGFR:CBL), Canis familiaris" + xref: Reactome:REACT_111103 "Autophosphorylation of KIT, Homo sapiens" + xref: Reactome:REACT_83486 "Binding and activation of MAP Kinase, Drosophila melanogaster" + xref: Reactome:REACT_113054 "Autocatalytic phosphorylation of FGFR3c, Caenorhabditis elegans" + xref: Reactome:REACT_80684 "Activation of Vav1, Sus scrofa" + xref: Reactome:REACT_111186 "Phosphorylation of GAB2 by SFKs, Homo sapiens" + xref: Reactome:REACT_113688 "Phosphorylation of ITIM in SIRP alpha, Sus scrofa" + xref: Reactome:REACT_97562 "Phosphorylation of CBL (EGFR:CBL), Rattus norvegicus" GO:0004714 : transmembrane receptor protein tyrosine kinase activity - xref: Reactome:REACT_91374 "Shc phosphorylation by phospho-EGFR:EGF, Canis familiaris" - xref: Reactome:REACT_12592 "Shc phosphorylation by phospho-EGFR:EGF, Homo sapiens" - xref: Reactome:REACT_93045 "Shc phosphorylation by phospho-EGFR:EGF, Danio rerio" - xref: Reactome:REACT_100726 "ARMS is phosphorylated by active TrkA receptor, Sus scrofa" - xref: Reactome:REACT_104778 "Shc phosphorylation by phospho-EGFR:EGF, Taeniopygia guttata" - xref: Reactome:REACT_91057 "Shc phosphorylation by phospho-EGFR:EGF, Xenopus tropicalis" - xref: Reactome:REACT_107918 "Shc phosphorylation by phospho-EGFR:EGF, Gallus gallus" - xref: Reactome:REACT_95686 "Shc phosphorylation by phospho-EGFR:EGF, Rattus norvegicus" - xref: Reactome:REACT_87015 "Shc phosphorylation by phospho-EGFR:EGF, Mus musculus" + xref: Reactome:REACT_12592 "SHC1 phosphorylation by phosphorylated EGFR, Homo sapiens" + xref: Reactome:REACT_91057 "SHC1 phosphorylation by phosphorylated EGFR, Xenopus tropicalis" + xref: Reactome:REACT_87015 "SHC1 phosphorylation by phosphorylated EGFR, Mus musculus" + xref: Reactome:REACT_107918 "SHC1 phosphorylation by phosphorylated EGFR, Gallus gallus" + xref: Reactome:REACT_95686 "SHC1 phosphorylation by phosphorylated EGFR, Rattus norvegicus" + xref: Reactome:REACT_91374 "SHC1 phosphorylation by phosphorylated EGFR, Canis familiaris" + xref: Reactome:REACT_104778 "SHC1 phosphorylation by phosphorylated EGFR, Taeniopygia guttata" + xref: Reactome:REACT_93045 "SHC1 phosphorylation by phosphorylated EGFR, Danio rerio" GO:0004715 : non-membrane spanning protein tyrosine kinase activity + xref: Reactome:REACT_111235 "Lyn activates ERK, Homo sapiens" + xref: Reactome:REACT_111190 "JAK2 phosphorylation of IRS-1/2, Homo sapiens" + xref: Reactome:REACT_27185 "SHP2 is phosphorylated, Homo sapiens" + xref: Reactome:REACT_112421 "Fgr may phosphorylate p38 MAPK, Drosophila melanogaster" + xref: Reactome:REACT_111142 "Jak2 phosphorylates Stat1/Stat3, Mus musculus" + xref: Reactome:REACT_111211 "Stat5 tyrosine phosphorylation, Mus musculus" + xref: Reactome:REACT_111207 "JAK2 phosphorylates STAT1/STAT3, Homo sapiens" + xref: Reactome:REACT_112972 "Fgr may phosphorylate p38 MAPK, Oryza sativa" + xref: Reactome:REACT_112025 "Fgr may phosphorylate p38 MAPK, Dictyostelium discoideum" + xref: Reactome:REACT_113743 "Fgr may phosphorylate p38 MAPK, Arabidopsis thaliana" GO:0004721 : phosphoprotein phosphatase activity - xref: Reactome:REACT_88974 "Hypophosphorylation of RNA Pol II CTD by FCP1P protein, Canis familiaris" - xref: Reactome:REACT_107782 "Pp2a mediated localization of Rb protein in chromatin, Danio rerio" - xref: Reactome:REACT_82328 "Dephosphorylation of phospho-Cdh1, Saccharomyces cerevisiae" - xref: Reactome:REACT_96431 "Pp2a mediated localization of Rb protein in chromatin, Oryza sativa" - xref: Reactome:REACT_83901 "Pp2a mediated localization of Rb protein in chromatin, Gallus gallus" - xref: Reactome:REACT_28065 "Pp2a mediated localization of Rb protein in chromatin, Arabidopsis thaliana" - xref: Reactome:REACT_80852 "Dephosphorylation of nuclear Cyclin A:phosph-Cdc2 complexes, Sus scrofa" - xref: Reactome:REACT_79518 "Hypophosphorylation of RNA Pol II CTD by FCP1P protein, Saccharomyces cerevisiae" - xref: Reactome:REACT_92030 "Hypophosphorylation of RNA Pol II CTD by FCP1P protein, Bos taurus" - xref: Reactome:REACT_96195 "Pp2a mediated localization of Rb protein in chromatin, Rattus norvegicus" - xref: Reactome:REACT_92277 "Pp2a mediated localization of Rb protein in chromatin, Bos taurus" - xref: Reactome:REACT_95610 "Dephosphorylation of cyclin B2:phospho-Cdc2 (Thr 14) by Cdc25, Sus scrofa" - xref: Reactome:REACT_95002 "Pp2a mediated localization of Rb protein in chromatin, Sus scrofa" + xref: Reactome:REACT_112981 "Dephosphorylation of cyclin B2:phospho-Cdc2 (Thr 14) by Cdc25, Schizosaccharomyces pombe" + xref: Reactome:REACT_112348 "Dephosphorylation of cyclin B2:phospho-Cdc2 (Thr 14) by Cdc25, Saccharomyces cerevisiae" + xref: Reactome:REACT_98946 "Dephosphorylation of phospho-Cdh1, Saccharomyces cerevisiae" + xref: Reactome:REACT_112617 "Dephosphorylation of cytoplasmic Cyclin B1:phospho-Cdc2 (Thr 14, Tyr 15) complexes by Cdc25 phosphatases, Saccharomyces cerevisiae" + xref: Reactome:REACT_112795 "Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A, Saccharomyces cerevisiae" + xref: Reactome:REACT_111170 "Dephosphorylation of p130 (RBL2) by PP2A, Homo sapiens" + xref: Reactome:REACT_114200 "Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A, Schizosaccharomyces pombe" + xref: Reactome:REACT_111148 "Dephosphorylation of p107 (RBL1) by PP2A, Homo sapiens" + xref: Reactome:REACT_112020 "Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A, Drosophila melanogaster" + xref: Reactome:REACT_78414 "Hypophosphorylation of RNA Pol II CTD by FCP1P protein, Saccharomyces cerevisiae" + xref: Reactome:REACT_115084 "Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases, Saccharomyces cerevisiae" + xref: Reactome:REACT_113855 "Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases, Schizosaccharomyces pombe" + xref: Reactome:REACT_114550 "Dephosphorylation of cytoplasmic Cyclin B1:phospho-Cdc2 (Thr 14, Tyr 15) complexes by Cdc25 phosphatases, Schizosaccharomyces pombe" + xref: Reactome:REACT_112811 "Pp2a mediated localization of Rb protein in chromatin, Xenopus tropicalis" GO:0004722 : protein serine/threonine phosphatase activity - xref: Reactome:REACT_28811 "PHLPP dephosphorylates S473 in AKT, Caenorhabditis elegans" - xref: Reactome:REACT_80063 "DARPP-32 is dephosphorylated on Thr34 by PP2B, Sus scrofa" - xref: Reactome:REACT_106486 "AMPK is dephosphorylated, Bos taurus" + xref: Reactome:REACT_108076 "DARPP-32 is dephosphorylated on Thr34 by PP2B, Sus scrofa" + xref: Reactome:REACT_112659 "AMPK is dephosphorylated, Saccharomyces cerevisiae" + xref: Reactome:REACT_112210 "DARPP-32 is dephosphorylated on Thr34 by PP2B, Rattus norvegicus" + xref: Reactome:REACT_112525 "PHLPP dephosphorylates S473 in AKT, Gallus gallus" + xref: Reactome:REACT_111094 "PPA2A dephosphorylates SPRY2, Homo sapiens" + xref: Reactome:REACT_113935 "PHLPP dephosphorylates S473 in AKT, Xenopus tropicalis" + xref: Reactome:REACT_114990 "DARPP-32 is dephosphorylated on Thr34 by PP2B, Xenopus tropicalis" GO:0004725 : protein tyrosine phosphatase activity - xref: Reactome:REACT_82026 "Dephosphorylation of Lck-pY505 by CD45, Sus scrofa" - xref: Reactome:REACT_23816 "SHP1 and SHP2 dephosphorylate Bc Y628, Homo sapiens" + xref: Reactome:REACT_114866 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Arabidopsis thaliana" + xref: Reactome:REACT_115381 "Dephosphorylation of inactive SRC by PTPB1, Xenopus tropicalis" + xref: Reactome:REACT_112153 "Dephosphorylation of inactive SRC by PTPB1, Drosophila melanogaster" + xref: Reactome:REACT_111157 "SHP2 dephosphorylates SPRY2, Homo sapiens" + xref: Reactome:REACT_115220 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Dictyostelium discoideum" + xref: Reactome:REACT_111193 "Shp1 (Ptpn6) dephosphorylates Jak2, Mus musculus" + xref: Reactome:REACT_23816 "SHP1 and SHP2 dephosphorylate Y628 of IL3RB, Homo sapiens" + xref: Reactome:REACT_113070 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Caenorhabditis elegans" + xref: Reactome:REACT_112085 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Oryza sativa" + xref: Reactome:REACT_111128 "PTP1B dephosphorylates JAK2, Homo sapiens" + xref: Reactome:REACT_111061 "PTP1B dephosphorylates GHR, Homo sapiens" + xref: Reactome:REACT_111038 "Ptp1b dephosphorylates Jak2, Mus musculus" + xref: Reactome:REACT_111048 "SHP1 (PTPN6) dephosphorylates JAK2, Homo sapiens" GO:0004729 : oxygen-dependent protoporphyrinogen oxidase activity - xref: Reactome:REACT_28216 "Oxidation of protoporphyrinogen IX to protoporphyrin IX, Dictyostelium discoideum" + xref: Reactome:REACT_81276 "Oxidation of protoporphyrinogen IX to protoporphyrin IX, Dictyostelium discoideum" GO:0004731 : purine-nucleoside phosphorylase activity - xref: Reactome:REACT_83767 "(deoxy)inosine + orthophosphate <=> hypoxanthine + (deoxy)ribose 1-phosphate [NP], Bos taurus" - xref: Reactome:REACT_92324 "guanine + (deoxy)ribose 1-phosphate <=> (deoxy)guanosine + orthophosphate [NP], Saccharomyces cerevisiae" - xref: Reactome:REACT_95388 "hypoxanthine + (deoxy)ribose 1-phosphate <=> (deoxy)inosine + orthophosphate [NP], Saccharomyces cerevisiae" + xref: Reactome:REACT_95751 "(deoxy)inosine + orthophosphate <=> hypoxanthine + (deoxy)ribose 1-phosphate [NP], Bos taurus" + xref: Reactome:REACT_109206 "guanine + (deoxy)ribose 1-phosphate <=> (deoxy)guanosine + orthophosphate [NP], Saccharomyces cerevisiae" + xref: Reactome:REACT_84275 "hypoxanthine + (deoxy)ribose 1-phosphate <=> (deoxy)inosine + orthophosphate [NP], Saccharomyces cerevisiae" GO:0004735 : pyrroline-5-carboxylate reductase activity + xref: Reactome:REACT_113065 "L-1-pyrroline-5-carboxylate + NADPH + H+ => proline + NADP+, Oryza sativa" + xref: Reactome:REACT_113421 "L-1-pyrroline-5-carboxylate + NADPH + H+ => proline + NADP+, Plasmodium falciparum" + xref: Reactome:REACT_114311 "L-1-pyrroline-5-carboxylate + NADPH + H+ => proline + NADP+, Sus scrofa" + xref: Reactome:REACT_113362 "L-1-pyrroline-5-carboxylate + NADPH + H+ => proline + NADP+, Arabidopsis thaliana" GO:0004740 : pyruvate dehydrogenase (acetyl-transferring) kinase activity - xref: Reactome:REACT_78327 "PDK-catalyzed phosphorylation (inactivation) of PDC E1 alpha subunit, Schizosaccharomyces pombe" GO:0004743 : pyruvate kinase activity - xref: Reactome:REACT_94102 "phosphoenolpyruvate + ADP => pyruvate + ATP, Sus scrofa" + xref: Reactome:REACT_91947 "phosphoenolpyruvate + ADP => pyruvate + ATP, Sus scrofa" + xref: Reactome:REACT_112705 "phosphoenolpyruvate + ADP => pyruvate + ATP, Oryza sativa" + xref: Reactome:REACT_114481 "phosphoenolpyruvate + ADP => pyruvate + ATP, Plasmodium falciparum" + xref: Reactome:REACT_114095 "phosphoenolpyruvate + ADP => pyruvate + ATP, Arabidopsis thaliana" GO:0004748 : ribonucleoside-diphosphate reductase activity - xref: Reactome:REACT_31285 "NDP + reduced thioredoxin => dNDP + oxidized thioredoxin + H2O, Schizosaccharomyces pombe" - xref: Reactome:REACT_91522 "NDP + reduced thioredoxin => dNDP + oxidized thioredoxin + H2O, Bos taurus" - xref: Reactome:REACT_79810 "NDP + reduced glutaredoxin => dNDP + oxidized glutaredoxin + H2O, Schizosaccharomyces pombe" - xref: Reactome:REACT_81083 "NDP + reduced thioredoxin => dNDP + oxidized thioredoxin + H2O, Schizosaccharomyces pombe" - xref: Reactome:REACT_110451 "NDP + reduced glutaredoxin => dNDP + oxidized glutaredoxin + H2O, Saccharomyces cerevisiae" + xref: Reactome:REACT_115326 "NDP + reduced thioredoxin => dNDP + oxidized thioredoxin + H2O, Caenorhabditis elegans" + xref: Reactome:REACT_113565 "NDP + reduced thioredoxin => dNDP + oxidized thioredoxin + H2O, Caenorhabditis elegans" + xref: Reactome:REACT_34006 "NDP + reduced thioredoxin => dNDP + oxidized thioredoxin + H2O, Bos taurus" GO:0004749 : ribose phosphate diphosphokinase activity - xref: Reactome:REACT_99413 "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate, Sus scrofa" - xref: Reactome:REACT_32768 "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate, Taeniopygia guttata" - xref: Reactome:REACT_84508 "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate, Bos taurus" - xref: Reactome:REACT_100928 "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate, Taeniopygia guttata" - xref: Reactome:REACT_79866 "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate, Saccharomyces cerevisiae" + xref: Reactome:REACT_31823 "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate, Bos taurus" + xref: Reactome:REACT_114942 "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate, Xenopus tropicalis" + xref: Reactome:REACT_101576 "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate, Saccharomyces cerevisiae" + xref: Reactome:REACT_94569 "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate, Sus scrofa" + xref: Reactome:REACT_113259 "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate, Xenopus tropicalis" GO:0004750 : ribulose-phosphate 3-epimerase activity - xref: Reactome:REACT_34090 "xylulose 5-phosphate <=> D-ribulose 5-phosphate, Bos taurus" + xref: Reactome:REACT_81057 "xylulose 5-phosphate <=> D-ribulose 5-phosphate, Bos taurus" + xref: Reactome:REACT_113659 "D-ribulose 5-phosphate <=> xylulose 5-phosphate, Sus scrofa" + xref: Reactome:REACT_114208 "xylulose 5-phosphate <=> D-ribulose 5-phosphate, Sus scrofa" GO:0004751 : ribose-5-phosphate isomerase activity - xref: Reactome:REACT_110556 "D-ribulose 5-phosphate <=> ribose 5-phosphate, Plasmodium falciparum" + xref: Reactome:REACT_113206 "D-ribulose 5-phosphate <=> ribose 5-phosphate, Arabidopsis thaliana" + xref: Reactome:REACT_34759 "D-ribulose 5-phosphate <=> ribose 5-phosphate, Plasmodium falciparum" + xref: Reactome:REACT_115365 "D-ribulose 5-phosphate <=> ribose 5-phosphate, Oryza sativa" + xref: Reactome:REACT_115286 "ribose 5-phosphate <=> D-ribulose 5-phosphate, Arabidopsis thaliana" + xref: Reactome:REACT_114043 "ribose 5-phosphate <=> D-ribulose 5-phosphate, Oryza sativa" GO:0004757 : sepiapterin reductase activity + xref: Reactome:REACT_111093 "PTHP is reduced to BH4 by sepiapterin reductase (SPR), Homo sapiens" + xref: Reactome:REACT_111234 "Salvage - Sepiapterin is reduced to BH2, Homo sapiens" GO:0004758 : serine C-palmitoyltransferase activity + xref: Reactome:REACT_113202 "palmitoyl-CoA + serine => 3-ketosphinganine + CoASH + CO2, Plasmodium falciparum" GO:0004766 : spermidine synthase activity - xref: Reactome:REACT_29263 "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine, Dictyostelium discoideum" - xref: Reactome:REACT_87445 "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine, Mycobacterium tuberculosis" + xref: Reactome:REACT_31767 "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine, Dictyostelium discoideum" GO:0004767 : sphingomyelin phosphodiesterase activity - xref: Reactome:REACT_102767 "Production of ceramide which can activate JNK and other targets, Sus scrofa" + xref: Reactome:REACT_88771 "Production of ceramide which can activate JNK and other targets, Sus scrofa" GO:0004769 : steroid delta-isomerase activity - xref: Reactome:REACT_32083 "Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol, Bos taurus" + xref: Reactome:REACT_114179 "DHA isomerizes to 4-Androstene3,17-dione, Escherichia coli" + xref: Reactome:REACT_93338 "Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol, Bos taurus" + xref: Reactome:REACT_113857 "Pregn-5-ene-3,20-dione isomerizes to progesterone, Mycobacterium tuberculosis" + xref: Reactome:REACT_112222 "Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone, Mycobacterium tuberculosis" + xref: Reactome:REACT_112738 "Pregn-5-ene-3,20-dione isomerizes to progesterone, Escherichia coli" + xref: Reactome:REACT_114390 "Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol, Arabidopsis thaliana" + xref: Reactome:REACT_114902 "Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol, Oryza sativa" + xref: Reactome:REACT_113969 "DHA isomerizes to 4-Androstene3,17-dione, Mycobacterium tuberculosis" + xref: Reactome:REACT_113344 "Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone, Escherichia coli" GO:0004775 : succinate-CoA ligase (ADP-forming) activity - xref: Reactome:REACT_79399 "ADP + Orthophosphate + Succinyl-CoA <=> ATP + Succinate + CoA, Schizosaccharomyces pombe" - xref: Reactome:REACT_34061 "ADP + Orthophosphate + Succinyl-CoA <=> ATP + Succinate + CoA, Saccharomyces cerevisiae" - xref: Reactome:REACT_87261 "ADP + Orthophosphate + Succinyl-CoA <=> ATP + Succinate + CoA, Plasmodium falciparum" - xref: Reactome:REACT_106724 "ADP + Orthophosphate + Succinyl-CoA <=> ATP + Succinate + CoA, Dictyostelium discoideum" GO:0004776 : succinate-CoA ligase (GDP-forming) activity - xref: Reactome:REACT_31838 "GDP + Orthophosphate + Succinyl-CoA <=> GTP + Succinate + CoA, Dictyostelium discoideum" - xref: Reactome:REACT_80781 "GDP + Orthophosphate + Succinyl-CoA <=> GTP + Succinate + CoA, Arabidopsis thaliana" - xref: Reactome:REACT_77973 "GDP + Orthophosphate + Succinyl-CoA <=> GTP + Succinate + CoA, Oryza sativa" GO:0004781 : sulfate adenylyltransferase (ATP) activity - xref: Reactome:REACT_33321 "ATP + sulfate => adenylyl sulfate (APS) + pyrophosphate, Schizosaccharomyces pombe" - xref: Reactome:REACT_106092 "ATP + sulfate => adenylyl sulfate (APS) + pyrophosphate, Saccharomyces cerevisiae" + xref: Reactome:REACT_112565 "ATP + sulfate => adenylyl sulfate (APS) + pyrophosphate, Escherichia coli" GO:0004788 : thiamine diphosphokinase activity - xref: Reactome:REACT_101961 "Thiamin is pyrophosphorylated, Bos taurus" + xref: Reactome:REACT_29244 "Thiamin is pyrophosphorylated, Bos taurus" GO:0004791 : thioredoxin-disulfide reductase activity + xref: Reactome:REACT_114582 "thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+, Caenorhabditis elegans" GO:0004801 : sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity - xref: Reactome:REACT_93089 "D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate, Schizosaccharomyces pombe" - xref: Reactome:REACT_101200 "D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate, Saccharomyces cerevisiae" + xref: Reactome:REACT_105812 "D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate, Saccharomyces cerevisiae" + xref: Reactome:REACT_100775 "D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate, Schizosaccharomyces pombe" GO:0004806 : triglyceride lipase activity - xref: Reactome:REACT_96952 "triacylglycerol + H2O -> diacylglycerol + fatty acid, Drosophila melanogaster" + xref: Reactome:REACT_113800 "triacylglycerol + H2O -> diacylglycerol + fatty acid, Danio rerio" GO:0004807 : triose-phosphate isomerase activity - xref: Reactome:REACT_89134 "dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate, Arabidopsis thaliana" - xref: Reactome:REACT_96255 "D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate, Arabidopsis thaliana" - xref: Reactome:REACT_94073 "dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate, Schizosaccharomyces pombe" - xref: Reactome:REACT_99351 "dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate, Oryza sativa" - xref: Reactome:REACT_107741 "D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate, Oryza sativa" + xref: Reactome:REACT_32420 "dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate, Schizosaccharomyces pombe" GO:0004813 : alanine-tRNA ligase activity - xref: Reactome:REACT_80161 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate, Bos taurus" + xref: Reactome:REACT_112870 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate, Staphylococcus aureus N315" + xref: Reactome:REACT_114945 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate, Oryza sativa" + xref: Reactome:REACT_114863 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate, Drosophila melanogaster" + xref: Reactome:REACT_114744 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate, Arabidopsis thaliana" + xref: Reactome:REACT_89789 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate, Bos taurus" + xref: Reactome:REACT_114834 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate, Arabidopsis thaliana" + xref: Reactome:REACT_113119 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate, Oryza sativa" + xref: Reactome:REACT_112886 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate, Caenorhabditis elegans" GO:0004814 : arginine-tRNA ligase activity - xref: Reactome:REACT_98705 "arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate, Bos taurus" - xref: Reactome:REACT_30179 "arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate, Mycobacterium tuberculosis" - xref: Reactome:REACT_110209 "arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate, Staphylococcus aureus N315" - xref: Reactome:REACT_99992 "arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate, Dictyostelium discoideum" + xref: Reactome:REACT_114854 "arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate, Arabidopsis thaliana" + xref: Reactome:REACT_101912 "arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate, Dictyostelium discoideum" + xref: Reactome:REACT_101377 "arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate, Bos taurus" GO:0004815 : aspartate-tRNA ligase activity - xref: Reactome:REACT_99417 "aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate, Bos taurus" - xref: Reactome:REACT_109531 "aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate, Plasmodium falciparum" - xref: Reactome:REACT_28643 "aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate, Dictyostelium discoideum" + xref: Reactome:REACT_93154 "aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate, Dictyostelium discoideum" + xref: Reactome:REACT_31439 "aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate, Bos taurus" + xref: Reactome:REACT_112613 "aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate, Arabidopsis thaliana" GO:0004816 : asparagine-tRNA ligase activity - xref: Reactome:REACT_84108 "asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate, Staphylococcus aureus N315" + xref: Reactome:REACT_115176 "asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate, Staphylococcus aureus N315" GO:0004817 : cysteine-tRNA ligase activity - xref: Reactome:REACT_100589 "cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate, Sus scrofa" - xref: Reactome:REACT_105688 "cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate, Mycobacterium tuberculosis" - xref: Reactome:REACT_90834 "cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate, Mycobacterium tuberculosis" + xref: Reactome:REACT_33699 "cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate, Sus scrofa" GO:0004818 : glutamate-tRNA ligase activity - xref: Reactome:REACT_82819 "glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate, Dictyostelium discoideum" - xref: Reactome:REACT_33213 "glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate, Escherichia coli" - xref: Reactome:REACT_79886 "glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate, Bos taurus" + xref: Reactome:REACT_79594 "glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate, Dictyostelium discoideum" + xref: Reactome:REACT_99054 "glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate, Bos taurus" + xref: Reactome:REACT_112102 "glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate, Arabidopsis thaliana" GO:0004819 : glutamine-tRNA ligase activity + xref: Reactome:REACT_114946 "glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate, Arabidopsis thaliana" GO:0004820 : glycine-tRNA ligase activity - xref: Reactome:REACT_98118 "glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate, Bos taurus" - xref: Reactome:REACT_100213 "glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate, Dictyostelium discoideum" + xref: Reactome:REACT_29415 "glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate, Dictyostelium discoideum" + xref: Reactome:REACT_104151 "glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate, Bos taurus" GO:0004821 : histidine-tRNA ligase activity - xref: Reactome:REACT_79169 "histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate, Bos taurus" - xref: Reactome:REACT_86803 "histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate, Dictyostelium discoideum" - xref: Reactome:REACT_87118 "histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate, Bos taurus" + xref: Reactome:REACT_30681 "histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate, Bos taurus" + xref: Reactome:REACT_104519 "histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate, Bos taurus" + xref: Reactome:REACT_86389 "histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate, Dictyostelium discoideum" GO:0004822 : isoleucine-tRNA ligase activity + xref: Reactome:REACT_112356 "isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate, Plasmodium falciparum" + xref: Reactome:REACT_112543 "isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate, Arabidopsis thaliana" GO:0004823 : leucine-tRNA ligase activity + xref: Reactome:REACT_113044 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Arabidopsis thaliana" GO:0004824 : lysine-tRNA ligase activity + xref: Reactome:REACT_112322 "lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate, Arabidopsis thaliana" + xref: Reactome:REACT_112280 "lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate, Staphylococcus aureus N315" + xref: Reactome:REACT_113853 "lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate, Arabidopsis thaliana" GO:0004825 : methionine-tRNA ligase activity + xref: Reactome:REACT_115242 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Escherichia coli" + xref: Reactome:REACT_112913 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Rattus norvegicus" + xref: Reactome:REACT_113646 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Danio rerio" + xref: Reactome:REACT_114923 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Mycobacterium tuberculosis" + xref: Reactome:REACT_113638 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Plasmodium falciparum" + xref: Reactome:REACT_113546 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Arabidopsis thaliana" + xref: Reactome:REACT_113871 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Arabidopsis thaliana" + xref: Reactome:REACT_113488 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Taeniopygia guttata" + xref: Reactome:REACT_112814 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Oryza sativa" + xref: Reactome:REACT_115107 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Caenorhabditis elegans" + xref: Reactome:REACT_114281 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Canis familiaris" + xref: Reactome:REACT_113327 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Schizosaccharomyces pombe" + xref: Reactome:REACT_114409 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Gallus gallus" + xref: Reactome:REACT_112985 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Saccharomyces cerevisiae" + xref: Reactome:REACT_114525 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Drosophila melanogaster" + xref: Reactome:REACT_113473 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Bos taurus" + xref: Reactome:REACT_114216 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Mus musculus" + xref: Reactome:REACT_112098 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Dictyostelium discoideum" + xref: Reactome:REACT_112796 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Sus scrofa" + xref: Reactome:REACT_114728 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Staphylococcus aureus N315" + xref: Reactome:REACT_114871 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Xenopus tropicalis" GO:0004826 : phenylalanine-tRNA ligase activity - xref: Reactome:REACT_34242 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Caenorhabditis elegans" + xref: Reactome:REACT_114689 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Dictyostelium discoideum" + xref: Reactome:REACT_114633 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Saccharomyces cerevisiae" + xref: Reactome:REACT_112342 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Gallus gallus" + xref: Reactome:REACT_112609 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Arabidopsis thaliana" + xref: Reactome:REACT_112009 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Oryza sativa" + xref: Reactome:REACT_115103 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Xenopus tropicalis" + xref: Reactome:REACT_114559 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Caenorhabditis elegans" + xref: Reactome:REACT_114632 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Plasmodium falciparum" + xref: Reactome:REACT_77960 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Caenorhabditis elegans" + xref: Reactome:REACT_113739 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Drosophila melanogaster" + xref: Reactome:REACT_112442 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Schizosaccharomyces pombe" GO:0004827 : proline-tRNA ligase activity - xref: Reactome:REACT_85055 "proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate, Schizosaccharomyces pombe" + xref: Reactome:REACT_113180 "proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate, Arabidopsis thaliana" + xref: Reactome:REACT_34251 "proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate, Schizosaccharomyces pombe" GO:0004828 : serine-tRNA ligase activity - xref: Reactome:REACT_90889 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate, Escherichia coli" - xref: Reactome:REACT_98765 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate, Bos taurus" - xref: Reactome:REACT_85157 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate, Mycobacterium tuberculosis" - xref: Reactome:REACT_77123 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate, Staphylococcus aureus N315" + xref: Reactome:REACT_115009 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate, Escherichia coli" + xref: Reactome:REACT_114211 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate, Plasmodium falciparum" + xref: Reactome:REACT_112205 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate, Staphylococcus aureus N315" + xref: Reactome:REACT_113323 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate, Mycobacterium tuberculosis" + xref: Reactome:REACT_105286 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate, Bos taurus" GO:0004829 : threonine-tRNA ligase activity - xref: Reactome:REACT_33563 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Saccharomyces cerevisiae" - xref: Reactome:REACT_78111 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Dictyostelium discoideum" - xref: Reactome:REACT_33550 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Schizosaccharomyces pombe" - xref: Reactome:REACT_83289 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Drosophila melanogaster" - xref: Reactome:REACT_97397 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Caenorhabditis elegans" - xref: Reactome:REACT_33606 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Caenorhabditis elegans" - xref: Reactome:REACT_29947 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Schizosaccharomyces pombe" - xref: Reactome:REACT_90829 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Saccharomyces cerevisiae" - xref: Reactome:REACT_99099 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Dictyostelium discoideum" - xref: Reactome:REACT_106118 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Drosophila melanogaster" + xref: Reactome:REACT_112924 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Xenopus tropicalis" GO:0004830 : tryptophan-tRNA ligase activity - xref: Reactome:REACT_92679 "tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate, Dictyostelium discoideum" + xref: Reactome:REACT_104142 "tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate, Dictyostelium discoideum" GO:0004831 : tyrosine-tRNA ligase activity + xref: Reactome:REACT_113020 "tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate, Drosophila melanogaster" + xref: Reactome:REACT_113391 "tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate, Escherichia coli" GO:0004832 : valine-tRNA ligase activity + xref: Reactome:REACT_114299 "valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate, Mycobacterium tuberculosis" GO:0004838 : L-tyrosine:2-oxoglutarate aminotransferase activity - xref: Reactome:REACT_83064 "tyrosine + alpha-ketoglutarate <=> p-hydroxyphenylpyruvate + glutamate, Bos taurus" + xref: Reactome:REACT_96541 "tyrosine + alpha-ketoglutarate <=> p-hydroxyphenylpyruvate + glutamate, Bos taurus" GO:0004842 : ubiquitin-protein ligase activity - xref: Reactome:REACT_90441 "Cbl-mediated ubiquitination of CIN85, Canis familiaris" - xref: Reactome:REACT_92278 "Cbl escapes Cdc42-mediated inhibition by down-regulating the adaptor molecule betaPix, Rattus norvegicus" - xref: Reactome:REACT_80813 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Rattus norvegicus" - xref: Reactome:REACT_96591 "Cbl-mediated ubiquitination of CIN85, Xenopus tropicalis" - xref: Reactome:REACT_78373 "Ubiquitination of stimulated EGFR (Cbl), Xenopus tropicalis" - xref: Reactome:REACT_12432 "Cbl binds and ubiquitinates Phospho-Sprouty, Homo sapiens" - xref: Reactome:REACT_12381 "Cbl ubiquitinates Sprouty, Homo sapiens" - xref: Reactome:REACT_94564 "Cbl escapes Cdc42-mediated inhibition by down-regulating the adaptor molecule betaPix, Taeniopygia guttata" - xref: Reactome:REACT_80572 "Cbl-mediated ubiquitination of CIN85, Taeniopygia guttata" - xref: Reactome:REACT_12520 "Cbl-mediated ubiquitination of CIN85, Homo sapiens" - xref: Reactome:REACT_32642 "Cbl ubiquitinates Sprouty, Taeniopygia guttata" - xref: Reactome:REACT_88011 "Ubiquitination of Emi1 by SCF-beta-TrCP, Schizosaccharomyces pombe" - xref: Reactome:REACT_100102 "Ubiquitination of stimulated EGFR (Cbl:Grb2), Rattus norvegicus" - xref: Reactome:REACT_96059 "Ubiquitination of stimulated EGFR (Cbl:Grb2), Canis familiaris" - xref: Reactome:REACT_106550 "Ubiquitination of Emi1 by SCF-beta-TrCP, Caenorhabditis elegans" - xref: Reactome:REACT_101217 "Cbl binds and ubiquitinates Phospho-Sprouty, Rattus norvegicus" - xref: Reactome:REACT_96771 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Xenopus tropicalis" - xref: Reactome:REACT_94525 "Cbl escapes Cdc42-mediated inhibition by down-regulating the adaptor molecule betaPix, Xenopus tropicalis" - xref: Reactome:REACT_101822 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Mus musculus" - xref: Reactome:REACT_101216 "Cbl ubiquitinates Sprouty, Rattus norvegicus" - xref: Reactome:REACT_94265 "Cbl-mediated ubiquitination of CIN85, Caenorhabditis elegans" - xref: Reactome:REACT_81526 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Bos taurus" - xref: Reactome:REACT_33488 "Cbl binds and ubiquitinates Phospho-Sprouty, Danio rerio" - xref: Reactome:REACT_29045 "Cbl ubiquitinates Sprouty, Xenopus tropicalis" - xref: Reactome:REACT_99285 "Ubiquitination of stimulated EGFR (Cbl), Rattus norvegicus" - xref: Reactome:REACT_91516 "Ubiquitination of PER Proteins, Caenorhabditis elegans" - xref: Reactome:REACT_85337 "Cbl binds and ubiquitinates Phospho-Sprouty, Canis familiaris" - xref: Reactome:REACT_100856 "Cbl ubiquitinates Sprouty, Danio rerio" - xref: Reactome:REACT_106416 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Sus scrofa" - xref: Reactome:REACT_109798 "Cbl-mediated ubiquitination of CIN85, Mus musculus" - xref: Reactome:REACT_12515 "Ubiquitination of stimulated EGFR (Cbl), Homo sapiens" - xref: Reactome:REACT_89324 "Cbl-mediated ubiquitination of CIN85, Danio rerio" - xref: Reactome:REACT_93808 "Ubiquitination of stimulated EGFR (Cbl:Grb2), Danio rerio" - xref: Reactome:REACT_95866 "Ubiquitination of stimulated EGFR (Cbl:Grb2), Taeniopygia guttata" - xref: Reactome:REACT_92445 "Cbl binds and ubiquitinates Phospho-Sprouty, Xenopus tropicalis" - xref: Reactome:REACT_84826 "Ubiquitination of stimulated EGFR (Cbl), Mus musculus" - xref: Reactome:REACT_104593 "Autoubiquitination of phospho-COP1(Ser-387 ), Arabidopsis thaliana" - xref: Reactome:REACT_91446 "Ubiquitination of stimulated EGFR (Cbl:Grb2), Xenopus tropicalis" - xref: Reactome:REACT_101051 "Multiubiquitination of APC/C-associated Cdh1, Arabidopsis thaliana" - xref: Reactome:REACT_106407 "Cbl binds and ubiquitinates Phospho-Sprouty, Mus musculus" - xref: Reactome:REACT_84282 "Ubiquitination of stimulated EGFR (Cbl), Danio rerio" - xref: Reactome:REACT_85348 "Cbl-mediated ubiquitination of CIN85, Gallus gallus" - xref: Reactome:REACT_94165 "Cbl escapes Cdc42-mediated inhibition by down-regulating the adaptor molecule betaPix, Danio rerio" - xref: Reactome:REACT_81041 "Cbl escapes Cdc42-mediated inhibition by down-regulating the adaptor molecule betaPix, Mus musculus" - xref: Reactome:REACT_108400 "Ubiquitination of stimulated EGFR (Cbl), Taeniopygia guttata" - xref: Reactome:REACT_89086 "Ubiquitination of stimulated EGFR (Cbl), Canis familiaris" - xref: Reactome:REACT_12562 "Ubiquitination of stimulated EGFR (Cbl:Grb2), Homo sapiens" - xref: Reactome:REACT_94789 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Drosophila melanogaster" - xref: Reactome:REACT_102841 "Ubiquitination of stimulated EGFR (Cbl:Grb2), Bos taurus" - xref: Reactome:REACT_6786 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Homo sapiens" - xref: Reactome:REACT_97242 "Cbl binds and ubiquitinates Phospho-Sprouty, Taeniopygia guttata" - xref: Reactome:REACT_97494 "Ubiquitination of stimulated EGFR (Cbl:Grb2), Mus musculus" - xref: Reactome:REACT_86879 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Danio rerio" - xref: Reactome:REACT_88911 "Cbl ubiquitinates Sprouty, Mus musculus" - xref: Reactome:REACT_12451 "Cbl escapes Cdc42-mediated inhibition by down-regulating the adaptor molecule betaPix, Homo sapiens" - xref: Reactome:REACT_101618 "Ubiquitination of Cyclin A by APC/C:Cdc20 complex, Arabidopsis thaliana" - xref: Reactome:REACT_103721 "Cbl-mediated ubiquitination of CIN85, Rattus norvegicus" - xref: Reactome:REACT_106527 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Gallus gallus" - xref: Reactome:REACT_93940 "Cbl-mediated ubiquitination of CIN85, Drosophila melanogaster" - xref: Reactome:REACT_107859 "Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex, Arabidopsis thaliana" - xref: Reactome:REACT_34698 "Ubiquitination of Securin by phospho-APC/C:Cdc20 complex, Arabidopsis thaliana" - xref: Reactome:REACT_82956 "Cbl-mediated ubiquitination of CIN85, Bos taurus" - xref: Reactome:REACT_103376 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Taeniopygia guttata" - xref: Reactome:REACT_78171 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Canis familiaris" - xref: Reactome:REACT_62571 "Ubiquitination of stimulated EGFR (Cbl:Grb2), Gallus gallus" - xref: Reactome:REACT_104803 "Cbl ubiquitinates Sprouty, Canis familiaris" + xref: Reactome:REACT_92278 "CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix, Rattus norvegicus" + xref: Reactome:REACT_62571 "Ubiquitination of stimulated EGFR (CBL:GRB2), Gallus gallus" + xref: Reactome:REACT_86879 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Danio rerio" + xref: Reactome:REACT_95866 "Ubiquitination of stimulated EGFR (CBL:GRB2), Taeniopygia guttata" + xref: Reactome:REACT_81526 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Bos taurus" + xref: Reactome:REACT_100856 "CBL ubiquitinates Sprouty, Danio rerio" + xref: Reactome:REACT_89086 "Ubiquitination of stimulated EGFR (CBL), Canis familiaris" + xref: Reactome:REACT_93808 "Ubiquitination of stimulated EGFR (CBL:GRB2), Danio rerio" + xref: Reactome:REACT_112355 "Auto-ubiquitination of TRAF6, Bos taurus" + xref: Reactome:REACT_106407 "CBL binds and ubiquitinates phosphorylated Sprouty, Mus musculus" + xref: Reactome:REACT_103376 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Taeniopygia guttata" + xref: Reactome:REACT_82956 "CBL-mediated ubiquitination of CIN85, Bos taurus" + xref: Reactome:REACT_111231 "CBL ubiquitinates FRS2 and FGFR, Homo sapiens" + xref: Reactome:REACT_12520 "CBL-mediated ubiquitination of CIN85, Homo sapiens" + xref: Reactome:REACT_91446 "Ubiquitination of stimulated EGFR (CBL:GRB2), Xenopus tropicalis" + xref: Reactome:REACT_103721 "CBL-mediated ubiquitination of CIN85, Rattus norvegicus" + xref: Reactome:REACT_12515 "Ubiquitination of stimulated EGFR (CBL), Homo sapiens" + xref: Reactome:REACT_113192 "CBL ubiquitinates Sprouty, Bos taurus" + xref: Reactome:REACT_29045 "CBL ubiquitinates Sprouty, Xenopus tropicalis" + xref: Reactome:REACT_12432 "CBL binds and ubiquitinates phosphorylated Sprouty, Homo sapiens" + xref: Reactome:REACT_106527 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Gallus gallus" + xref: Reactome:REACT_90441 "CBL-mediated ubiquitination of CIN85, Canis familiaris" + xref: Reactome:REACT_102841 "Ubiquitination of stimulated EGFR (CBL:GRB2), Bos taurus" + xref: Reactome:REACT_101217 "CBL binds and ubiquitinates phosphorylated Sprouty, Rattus norvegicus" + xref: Reactome:REACT_112669 "CBL ubiquitinates Sprouty, Drosophila melanogaster" + xref: Reactome:REACT_12381 "CBL ubiquitinates Sprouty, Homo sapiens" + xref: Reactome:REACT_96591 "CBL-mediated ubiquitination of CIN85, Xenopus tropicalis" + xref: Reactome:REACT_96059 "Ubiquitination of stimulated EGFR (CBL:GRB2), Canis familiaris" + xref: Reactome:REACT_88911 "CBL ubiquitinates Sprouty, Mus musculus" + xref: Reactome:REACT_100102 "Ubiquitination of stimulated EGFR (CBL:GRB2), Rattus norvegicus" + xref: Reactome:REACT_84826 "Ubiquitination of stimulated EGFR (CBL), Mus musculus" + xref: Reactome:REACT_111089 "Ubiquitination of p130 (RBL2) by SCF (Skp2), Homo sapiens" + xref: Reactome:REACT_114042 "Auto-ubiquitination of TRAF6, Gallus gallus" + xref: Reactome:REACT_97494 "Ubiquitination of stimulated EGFR (CBL:GRB2), Mus musculus" + xref: Reactome:REACT_78171 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Canis familiaris" + xref: Reactome:REACT_80813 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Rattus norvegicus" + xref: Reactome:REACT_115175 "Ubiquitination of NEMO by TRAF6, Bos taurus" + xref: Reactome:REACT_32642 "CBL ubiquitinates Sprouty, Taeniopygia guttata" + xref: Reactome:REACT_78373 "Ubiquitination of stimulated EGFR (CBL), Xenopus tropicalis" + xref: Reactome:REACT_84282 "Ubiquitination of stimulated EGFR (CBL), Danio rerio" + xref: Reactome:REACT_92445 "CBL binds and ubiquitinates phosphorylated Sprouty, Xenopus tropicalis" + xref: Reactome:REACT_12562 "Ubiquitination of stimulated EGFR (CBL:GRB2), Homo sapiens" + xref: Reactome:REACT_6786 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Homo sapiens" + xref: Reactome:REACT_12451 "CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix, Homo sapiens" + xref: Reactome:REACT_115172 "Multiubiquitination of Nek2A, Dictyostelium discoideum" + xref: Reactome:REACT_114376 "Ubiquitination of Cyclin A by APC/C:Cdc20 complex, Oryza sativa" + xref: Reactome:REACT_94525 "CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix, Xenopus tropicalis" + xref: Reactome:REACT_85337 "CBL binds and ubiquitinates phosphorylated Sprouty, Canis familiaris" + xref: Reactome:REACT_89324 "CBL-mediated ubiquitination of CIN85, Danio rerio" + xref: Reactome:REACT_80572 "CBL-mediated ubiquitination of CIN85, Taeniopygia guttata" + xref: Reactome:REACT_106416 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Sus scrofa" + xref: Reactome:REACT_96771 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Xenopus tropicalis" + xref: Reactome:REACT_114074 "CBL ubiquitinates Sprouty, Gallus gallus" + xref: Reactome:REACT_33488 "CBL binds and ubiquitinates phosphorylated Sprouty, Danio rerio" + xref: Reactome:REACT_85348 "CBL-mediated ubiquitination of CIN85, Gallus gallus" + xref: Reactome:REACT_104803 "CBL ubiquitinates Sprouty, Canis familiaris" + xref: Reactome:REACT_101822 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Mus musculus" + xref: Reactome:REACT_99285 "Ubiquitination of stimulated EGFR (CBL), Rattus norvegicus" + xref: Reactome:REACT_94165 "CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix, Danio rerio" + xref: Reactome:REACT_113956 "Monoubiquitination of FANCI by the FA ubiquitin ligase complex, Xenopus tropicalis" + xref: Reactome:REACT_94789 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Drosophila melanogaster" + xref: Reactome:REACT_93940 "CBL-mediated ubiquitination of CIN85, Drosophila melanogaster" + xref: Reactome:REACT_114678 "Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling, Danio rerio" + xref: Reactome:REACT_81041 "CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix, Mus musculus" + xref: Reactome:REACT_112448 "Ubiquitination of NEMO by TRAF6, Xenopus tropicalis" + xref: Reactome:REACT_109798 "CBL-mediated ubiquitination of CIN85, Mus musculus" + xref: Reactome:REACT_101216 "CBL ubiquitinates Sprouty, Rattus norvegicus" + xref: Reactome:REACT_111141 "Phosphorylated SPRY2 is ubiquitinated by CBL, Homo sapiens" + xref: Reactome:REACT_112414 "Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling, Danio rerio" GO:0004844 : uracil DNA N-glycosylase activity - xref: Reactome:REACT_85604 "Cleavage of 5-hydroxyluracil by UNG2 glycosylase, Schizosaccharomyces pombe" - xref: Reactome:REACT_83829 "Cleavage of uracil by UNG2 glycosylase, Saccharomyces cerevisiae" - xref: Reactome:REACT_79040 "Cleavage of uracil by UNG2 glycosylase, Danio rerio" - xref: Reactome:REACT_92529 "Cleavage of 5-hydroxyluracil by UNG2 glycosylase, Danio rerio" - xref: Reactome:REACT_87147 "Cleavage of 5-hydroxyluracil by UNG2 glycosylase, Saccharomyces cerevisiae" - xref: Reactome:REACT_84632 "Cleavage of uracil by UNG2 glycosylase, Schizosaccharomyces pombe" GO:0004855 : xanthine oxidase activity - xref: Reactome:REACT_108625 "Xanthine + H2O + O2 => Urate + H2O2, Bos taurus" + xref: Reactome:REACT_115203 "Hypoxanthine + H2O + O2 => Xanthine + H2O2, Mycobacterium tuberculosis" + xref: Reactome:REACT_113063 "Hypoxanthine + H2O + O2 => Xanthine + H2O2, Escherichia coli" + xref: Reactome:REACT_113574 "Xanthine + H2O + O2 => Urate + H2O2, Mycobacterium tuberculosis" + xref: Reactome:REACT_113246 "Xanthine + H2O + O2 => Urate + H2O2, Escherichia coli" + xref: Reactome:REACT_114723 "Xanthine + H2O + O2 => Urate + H2O2, Dictyostelium discoideum" + xref: Reactome:REACT_87777 "Xanthine + H2O + O2 => Urate + H2O2, Bos taurus" + xref: Reactome:REACT_114235 "Hypoxanthine + H2O + O2 => Xanthine + H2O2, Dictyostelium discoideum" GO:0004862 : cAMP-dependent protein kinase inhibitor activity + xref: Reactome:REACT_114726 "DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function, Xenopus tropicalis" GO:0004867 : serine-type endopeptidase inhibitor activity - xref: Reactome:REACT_33331 "fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1, Caenorhabditis elegans" - xref: Reactome:REACT_32455 "fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1, Caenorhabditis elegans" - xref: Reactome:REACT_110581 "urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 2 (PAI-2) -> PAI-2:urokinase plasminogen activator (two-chain):uPAR, Sus scrofa" - xref: Reactome:REACT_97566 "alpha-2-antiplasmin + plasmin -> alpha-2-antiplasmin:plasmin, Sus scrofa" + xref: Reactome:REACT_106218 "alpha-2-antiplasmin + plasmin -> alpha-2-antiplasmin:plasmin, Sus scrofa" + xref: Reactome:REACT_83397 "urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 2 (PAI-2) -> PAI-2:urokinase plasminogen activator (two-chain):uPAR, Sus scrofa" + xref: Reactome:REACT_113222 "alpha-2-antiplasmin + plasmin -> alpha-2-antiplasmin:plasmin, Xenopus tropicalis" GO:0004875 : complement receptor activity - is_a: GO:0001848 + relationship: has_part GO:0001848 GO:0004877 : complement component C3b receptor activity - is_a: GO:0001850 + relationship: has_part GO:0001850 + relationship: has_part GO:0001851 GO:0004878 : complement component C5a receptor activity - is_a: GO:0001856 + relationship: has_part GO:0001856 GO:0004880 : juvenile hormone receptor activity + relationship: has_part GO:0005500 GO:0004882 : androgen receptor activity + relationship: has_part GO:0005497 GO:0004887 : thyroid hormone receptor activity + relationship: has_part GO:0070324 GO:0004896 : cytokine receptor activity - is_a: GO:0019955 + relationship: has_part GO:0019955 GO:0004897 : ciliary neurotrophic factor receptor activity + relationship: has_part GO:0070119 GO:0004901 : granulocyte macrophage colony-stimulating factor receptor activity + relationship: has_part GO:0042021 GO:0004902 : granulocyte colony-stimulating factor receptor activity + relationship: has_part GO:0051916 GO:0004904 : interferon receptor activity - is_a: GO:0019961 + relationship: has_part GO:0019961 GO:0004905 : type I interferon receptor activity - is_a: GO:0019962 + relationship: has_part GO:0019962 GO:0004906 : interferon-gamma receptor activity - is_a: GO:0019964 + relationship: has_part GO:0019964 GO:0004908 : interleukin-1 receptor activity - is_a: GO:0019966 + relationship: has_part GO:0019966 GO:0004911 : interleukin-2 receptor activity - is_a: GO:0019976 + relationship: has_part GO:0019976 GO:0004912 : interleukin-3 receptor activity - is_a: GO:0019978 + relationship: has_part GO:0019978 GO:0004913 : interleukin-4 receptor activity - is_a: GO:0019979 + relationship: has_part GO:0019979 GO:0004914 : interleukin-5 receptor activity - is_a: GO:0019980 + relationship: has_part GO:0019980 GO:0004915 : interleukin-6 receptor activity - is_a: GO:0019981 + relationship: has_part GO:0019981 GO:0004917 : interleukin-7 receptor activity - is_a: GO:0019982 + relationship: has_part GO:0019982 GO:0004918 : interleukin-8 receptor activity - is_a: GO:0019959 + relationship: has_part GO:0019959 GO:0004919 : interleukin-9 receptor activity - is_a: GO:0019983 + relationship: has_part GO:0019983 GO:0004920 : interleukin-10 receptor activity - is_a: GO:0019969 + relationship: has_part GO:0019969 GO:0004921 : interleukin-11 receptor activity - is_a: GO:0019970 + relationship: has_part GO:0019970 GO:0004948 : calcitonin receptor activity + relationship: has_part GO:0032841 GO:0004950 : chemokine receptor activity - is_a: GO:0019956 + is_a: GO:0004896 + relationship: has_part GO:0019956 GO:0004952 : dopamine receptor activity - is_a: GO:0035240 + relationship: has_part GO:0035240 GO:0004968 : gonadotropin-releasing hormone receptor activity + relationship: has_part GO:0051448 GO:0004978 : corticotropin receptor activity - is_a: GO:0042562 + relationship: has_part GO:0042562 GO:0004980 : melanocyte-stimulating hormone receptor activity - is_a: GO:0042562 + relationship: has_part GO:0042562 GO:0005030 : neurotrophin receptor activity - is_a: GO:0043121 + relationship: has_part GO:0043121 GO:0005031 : tumor necrosis factor-activated receptor activity - name: tumor necrosis factor receptor activity + name: tumor necrosis factor-activated receptor activity + synonym: "tumor necrosis factor receptor activity" EXACT [GOC:bf, GOC:signaling] - is_a: GO:0043120 + relationship: has_part GO:0043120 GO:0005040 : decoy death receptor activity - is_a: GO:0005488 + relationship: has_part GO:0005488 GO:0005041 : low-density lipoprotein receptor activity - is_a: GO:0030169 + relationship: has_part GO:0030169 GO:0005047 : signal recognition particle binding - xref: Reactome:REACT_103640 "Interaction between SRP and SRP Receptor, Saccharomyces cerevisiae" - xref: Reactome:REACT_30696 "Interaction between SRP and SRP Receptor, Bos taurus" + xref: Reactome:REACT_28177 "Interaction between SRP and SRP Receptor, Saccharomyces cerevisiae" + xref: Reactome:REACT_94115 "Interaction between SRP and SRP Receptor, Bos taurus" GO:0005048 : signal sequence binding + xref: Reactome:REACT_113489 "Signal Recognition (Preprolactin), Gallus gallus" + xref: Reactome:REACT_113110 "Signal Recognition (Preproinsulin), Gallus gallus" + xref: Reactome:REACT_113823 "Signal Recognition (Preprolactin), Bos taurus" + xref: Reactome:REACT_112627 "Signal Recognition (Preproinsulin), Rattus norvegicus" + xref: Reactome:REACT_115380 "Signal Recognition (Preprolactin), Rattus norvegicus" + xref: Reactome:REACT_112794 "Signal Recognition (Preproinsulin), Bos taurus" GO:0005049 : nuclear export signal receptor activity - def: Combining with a nuclear export signal to initiate a change in cell activity. + def: Combining with a nuclear export signal (NES) to mediate transport of the NES-containing protein through the nuclear pore to the cytoplasm. - is_a: GO:0005515 + is_a: GO:0008565 + relationship: part_of GO:0006611 GO:0005085 : guanyl-nucleotide exchange factor activity - xref: Reactome:REACT_88096 "Activation of Gq by Muscarinic Acetylcholine Receptor M3, Caenorhabditis elegans" - xref: Reactome:REACT_110192 "Gs activation by prostacyclin receptor, Drosophila melanogaster" - xref: Reactome:REACT_33310 "Liganded Gz-activating GPCR acts as a GEF for Gz, Drosophila melanogaster" - xref: Reactome:REACT_110899 "Regeneration of eEF1A:GTP by eEF1B activity, Schizosaccharomyces pombe" - xref: Reactome:REACT_100221 "Regeneration of eEF1A:GTP by eEF1B activity, Arabidopsis thaliana" - xref: Reactome:REACT_80698 "Regeneration of eEF1A:GTP by eEF1B activity, Caenorhabditis elegans" - xref: Reactome:REACT_34343 "Liganded Gi-activating GPCR acts as a GEF for Gi, Caenorhabditis elegans" - xref: Reactome:REACT_102212 "Activation of Gq by Muscarinic Acetylcholine Receptor M3, Drosophila melanogaster" - xref: Reactome:REACT_95317 "Activation of Rap1 by membrane-associated GEFs, Sus scrofa" - xref: Reactome:REACT_98554 "Regeneration of eEF1A:GTP by eEF1B activity, Dictyostelium discoideum" - xref: Reactome:REACT_87937 "Liganded G12/13-activating GPCR acts as a GEF for G12/13, Sus scrofa" - xref: Reactome:REACT_97664 "Liganded Gq/11-activating GPCRs act as GEFs for Gq/11, Bos taurus" - xref: Reactome:REACT_90940 "VAV3 is a GEF for Rho/Rac family kinases, Xenopus tropicalis" - xref: Reactome:REACT_87231 "Liganded Gz-activating GPCR acts as a GEF for Gz, Sus scrofa" - xref: Reactome:REACT_83698 "Liganded Gz-activating GPCR acts as a GEF for Gz, Caenorhabditis elegans" - xref: Reactome:REACT_110552 "Regeneration of eEF1A:GTP by eEF1B activity, Saccharomyces cerevisiae" - xref: Reactome:REACT_79051 "G13 activation by TP receptor, Drosophila melanogaster" - xref: Reactome:REACT_85329 "VAV3 is a GEF for Rho/Rac family kinases, Taeniopygia guttata" - xref: Reactome:REACT_99828 "Sar1p Activation And Membrane Binding, Caenorhabditis elegans" - xref: Reactome:REACT_109777 "Liganded G12/13-activating GPCR acts as a GEF for G12/13, Caenorhabditis elegans" - xref: Reactome:REACT_101345 "Regeneration of eEF1A:GTP by eEF1B activity, Oryza sativa" - xref: Reactome:REACT_80201 "p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor, Arabidopsis thaliana" - xref: Reactome:REACT_95747 "p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor, Oryza sativa" - xref: Reactome:REACT_92764 "Liganded G12/13-activating GPCR acts as a GEF for G12/13, Drosophila melanogaster" - xref: Reactome:REACT_28165 "Activation of Rap1 by membrane-associated GEFs, Dictyostelium discoideum" - xref: Reactome:REACT_109172 "C3G stimulates nucleotide exchange on Rap1, Sus scrofa" - xref: Reactome:REACT_100888 "Gq activation by TP receptor, Drosophila melanogaster" + xref: Reactome:REACT_113541 "p115-RhoGEF activation of Rac1, Xenopus tropicalis" + xref: Reactome:REACT_113526 "Activation of Rap1 by membrane-associated GEFs, Drosophila melanogaster" + xref: Reactome:REACT_113598 "p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor, Dictyostelium discoideum" + xref: Reactome:REACT_112354 "Activation of RAC1, Mus musculus" + xref: Reactome:REACT_112768 "Activation of RAC1, Bos taurus" + xref: Reactome:REACT_114659 "Activation of Gq by Fatty Acid Receptor 1: Fatty Acid Complex, Danio rerio" + xref: Reactome:REACT_113090 "p115-RhoGEF activation of Rac1, Caenorhabditis elegans" + xref: Reactome:REACT_101114 "Activation of Rap1 by membrane-associated GEFs, Sus scrofa" + xref: Reactome:REACT_115111 "VAV3 is a GEF for Rho/Rac family kinases, Schizosaccharomyces pombe" + xref: Reactome:REACT_92743 "Liganded Gq/11-activating GPCRs act as GEFs for Gq/11, Bos taurus" + xref: Reactome:REACT_111195 "Activation of RAC1, Homo sapiens" + xref: Reactome:REACT_114904 "VAV3 is a GEF for Rho/Rac family kinases, Saccharomyces cerevisiae" + xref: Reactome:REACT_112243 "Activation of RAC1, Xenopus tropicalis" + xref: Reactome:REACT_113408 "VAV2 is a GEF for Rho/Rac family kinases, Saccharomyces cerevisiae" + xref: Reactome:REACT_115094 "VAV1 is a GEF for Rho/Rac family kinases, Caenorhabditis elegans" + xref: Reactome:REACT_112168 "Activation of Gq by Muscarinic Acetylcholine Receptor M3, Danio rerio" + xref: Reactome:REACT_113007 "Activation of RAC1, Canis familiaris" + xref: Reactome:REACT_29380 "Liganded G12/13-activating GPCR acts as a GEF for G12/13, Sus scrofa" + xref: Reactome:REACT_112276 "VAV2 is a GEF for Rho/Rac family kinases, Schizosaccharomyces pombe" + xref: Reactome:REACT_115210 "Activation of RAC1, Drosophila melanogaster" + xref: Reactome:REACT_90952 "Liganded Gz-activating GPCR acts as a GEF for Gz, Sus scrofa" GO:0005086 : ARF guanyl-nucleotide exchange factor activity - xref: Reactome:REACT_83517 "Arf1 Activation by GBF1, Saccharomyces cerevisiae" - xref: Reactome:REACT_64759 "trans-Golgi Network Coat Activation, Saccharomyces cerevisiae" - xref: Reactome:REACT_30645 "Arf1 Activation by GBF1, Schizosaccharomyces pombe" + xref: Reactome:REACT_90928 "Arf1 Activation by GBF1, Schizosaccharomyces pombe" GO:0005088 : Ras guanyl-nucleotide exchange factor activity - xref: Reactome:REACT_88657 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2), Canis familiaris" - xref: Reactome:REACT_96781 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2:Shc), Canis familiaris" - xref: Reactome:REACT_79439 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2:Shc), Bos taurus" - xref: Reactome:REACT_77575 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2:Shc), Mus musculus" - xref: Reactome:REACT_102004 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2), Danio rerio" - xref: Reactome:REACT_102156 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2), Rattus norvegicus" - xref: Reactome:REACT_102522 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2:Shc), Gallus gallus" - xref: Reactome:REACT_88810 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2), Mus musculus" - xref: Reactome:REACT_98780 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2:Shc), Xenopus tropicalis" - xref: Reactome:REACT_93477 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2), Taeniopygia guttata" - xref: Reactome:REACT_100714 "Sos-mediated nucleotide exchange of Ras (PDGF receptor:Grb2:Sos), Drosophila melanogaster" - xref: Reactome:REACT_87691 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2), Xenopus tropicalis" - xref: Reactome:REACT_101653 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2), Bos taurus" - xref: Reactome:REACT_77034 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2), Gallus gallus" - xref: Reactome:REACT_12402 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2:Shc), Homo sapiens" - xref: Reactome:REACT_98264 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2:Shc), Danio rerio" - xref: Reactome:REACT_106236 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2:Shc), Taeniopygia guttata" - xref: Reactome:REACT_103870 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2:Shc), Rattus norvegicus" - xref: Reactome:REACT_12386 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2), Homo sapiens" + xref: Reactome:REACT_102522 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1), Gallus gallus" + xref: Reactome:REACT_111095 "Ras nucleotide exchange by GRB2:SOS1 through p-SHC, Homo sapiens" + xref: Reactome:REACT_93477 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1), Taeniopygia guttata" + xref: Reactome:REACT_77575 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1), Mus musculus" + xref: Reactome:REACT_106236 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1), Taeniopygia guttata" + xref: Reactome:REACT_101653 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1), Bos taurus" + xref: Reactome:REACT_12402 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1), Homo sapiens" + xref: Reactome:REACT_12386 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1), Homo sapiens" + xref: Reactome:REACT_77034 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1), Gallus gallus" + xref: Reactome:REACT_79439 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1), Bos taurus" + xref: Reactome:REACT_88810 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1), Mus musculus" + xref: Reactome:REACT_111091 "Activation of RAS by p-KIT bound SOS1, Homo sapiens" + xref: Reactome:REACT_102004 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1), Danio rerio" + xref: Reactome:REACT_87691 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1), Xenopus tropicalis" + xref: Reactome:REACT_96781 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1), Canis familiaris" + xref: Reactome:REACT_98264 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1), Danio rerio" + xref: Reactome:REACT_88657 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1), Canis familiaris" + xref: Reactome:REACT_98780 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1), Xenopus tropicalis" + xref: Reactome:REACT_111126 "Ras nucleotide exchange by GRB2:SOS1 bound to p-FRS2:activated FGFR, Homo sapiens" + xref: Reactome:REACT_103870 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1), Rattus norvegicus" + xref: Reactome:REACT_102156 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1), Rattus norvegicus" GO:0005089 : Rho guanyl-nucleotide exchange factor activity - xref: Reactome:REACT_90495 "Activation of Cdc42, Sus scrofa" - xref: Reactome:REACT_32109 "Activation of Rac1, Taeniopygia guttata" - xref: Reactome:REACT_88977 "Activation of Cdc42, Taeniopygia guttata" + xref: Reactome:REACT_96181 "Activation of Cdc42, Sus scrofa" + xref: Reactome:REACT_112014 "RhoA is activated by nucleotide exchange and inhibits axonal growth, Danio rerio" + xref: Reactome:REACT_114487 "RhoA is activated by nucleotide exchange and inhibits axonal growth, Rattus norvegicus" + xref: Reactome:REACT_114452 "RhoA is activated by nucleotide exchange and inhibits axonal growth, Xenopus tropicalis" GO:0005096 : GTPase activator activity - xref: Reactome:REACT_88349 "Hydrolysis of Arf1-GTP to Arf1-GDP, Dictyostelium discoideum" - xref: Reactome:REACT_86672 "Hydrolysis of Arf1-GTP to Arf1-GDP, Oryza sativa" - xref: Reactome:REACT_79656 "GAPs inactivate Rho GTPase:GTP by hydrolysis, Schizosaccharomyces pombe" - xref: Reactome:REACT_104681 "TSC2 activates intrinsic GTPase activity of Rheb, Bos taurus" + xref: Reactome:REACT_115497 "Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity, Xenopus tropicalis" + xref: Reactome:REACT_29936 "GAPs inactivate Rho GTPase:GTP by hydrolysis, Schizosaccharomyces pombe" + xref: Reactome:REACT_85789 "Hydrolysis of Arf1-GTP to Arf1-GDP, Dictyostelium discoideum" + xref: Reactome:REACT_115083 "Inactivation of R-Ras by Sema3A-Plexin-A GAP activity, Xenopus tropicalis" + xref: Reactome:REACT_112033 "Hydrolysis of Arf1-GTP to Arf1-GDP, Saccharomyces cerevisiae" + xref: Reactome:REACT_105205 "TSC2 activates intrinsic GTPase activity of Rheb, Bos taurus" GO:0005100 : Rho GTPase activator activity + xref: Reactome:REACT_115214 "Inactivation of Rho-GTP by p190RhoGAP, Rattus norvegicus" + xref: Reactome:REACT_114368 "Inactivation of Rho-GTP by p190RhoGAP, Danio rerio" GO:0005160 : transforming growth factor beta receptor binding - xref: Reactome:REACT_99071 "BMP2 binds to the receptor complex, Sus scrofa" + xref: Reactome:REACT_105409 "BMP2 binds to the receptor complex, Sus scrofa" GO:0005231 : excitatory extracellular ligand-gated ion channel activity + xref: Reactome:REACT_113296 "Activation of Ca impermeable AMPA receptors, Xenopus tropicalis" + xref: Reactome:REACT_113112 "Unblocking of NMDA receptor, Xenopus tropicalis" + xref: Reactome:REACT_112384 "Membrane depolarization upon activation of Ca impermeable AMPA receptors, Caenorhabditis elegans" + xref: Reactome:REACT_112215 "Activation of Ca permeable AMPA receptors, Caenorhabditis elegans" + xref: Reactome:REACT_112878 "Membrane depolarization upon activation of Ca impermeable AMPA receptors, Xenopus tropicalis" + xref: Reactome:REACT_112847 "Unblocking of NMDA receptor, Caenorhabditis elegans" + xref: Reactome:REACT_115442 "Activation of Ca impermeable AMPA receptors, Caenorhabditis elegans" + xref: Reactome:REACT_115321 "Activation of Ca permeable AMPA receptors, Caenorhabditis elegans" GO:0005242 : inward rectifier potassium channel activity - xref: Reactome:REACT_75911 "Activation of ATP sensitive Potassium channels, Homo sapiens" + xref: Reactome:REACT_75911 "Activation of ATP sensitive Potassium channels in neuroendocrine cells, Homo sapiens" + xref: Reactome:REACT_111144 "Activation of ATP sensitive Potassium channels in muscle cells, Homo sapiens" GO:0005243 : gap junction channel activity - xref: Reactome:REACT_94968 "Connexin 62 mediated neuronal gap junction communication, Danio rerio" + xref: Reactome:REACT_112884 "Connexin 62 mediated neuronal gap junction communication, Xenopus tropicalis" + xref: Reactome:REACT_115511 "Pannexin 1/Pannexin2 mediated neuronal gap junction communication, Xenopus tropicalis" GO:0005253 : anion channel activity - xref: Reactome:REACT_79379 "Passive Transport of Anions out of Vesicles by Aquaporin-6, Oryza sativa" - xref: Reactome:REACT_33152 "Passive Transport of Anions out of Vesicles by Aquaporin-6, Arabidopsis thaliana" - xref: Reactome:REACT_82075 "Passive Transport of Anions into Vesicles by Aquaporin-6, Oryza sativa" - xref: Reactome:REACT_102125 "Passive Transport of Anions into Vesicles by Aquaporin-6, Arabidopsis thaliana" + xref: Reactome:REACT_112326 "Passive Transport of Anions out of Vesicles by Aquaporin-6, Drosophila melanogaster" + xref: Reactome:REACT_115461 "Passive Transport of Anions into Vesicles by Aquaporin-6, Escherichia coli" + xref: Reactome:REACT_115452 "Passive Transport of Anions into Vesicles by Aquaporin-6, Drosophila melanogaster" GO:0005254 : chloride channel activity - xref: Reactome:REACT_78973 "Group 3 - Selective Cl- transport, Caenorhabditis elegans" - xref: Reactome:REACT_83769 "Group 3 - Selective Cl- transport, Drosophila melanogaster" + xref: Reactome:REACT_114749 "Group 3 - Selective Cl- transport, Dictyostelium discoideum" + xref: Reactome:REACT_112123 "Group 3 - Selective Cl- transport, Plasmodium falciparum" GO:0005261 : cation channel activity + xref: Reactome:REACT_112207 "Release of calcium from intracellular stores by IP3 receptor activation, Caenorhabditis elegans" GO:0005262 : calcium channel activity - xref: Reactome:REACT_92531 "Ca2+ influx through voltage gated Ca2+ channels, Gallus gallus" + xref: Reactome:REACT_112676 "Transport of Ca++ from platelet dense tubular system to cytoplasm, Caenorhabditis elegans" + xref: Reactome:REACT_114130 "Ca2+ influx through voltage gated Ca2+ channels, Xenopus tropicalis" + xref: Reactome:REACT_112515 "P2X1-mediated entry of Ca++ from plasma, Xenopus tropicalis" GO:0005276 : vesicular hydrogen:amino acid antiporter activity + xref: Reactome:REACT_112465 "Vesicular inhibitory amino acid transport, Saccharomyces cerevisiae" + xref: Reactome:REACT_114587 "Vesicular inhibitory amino acid transport, Oryza sativa" + xref: Reactome:REACT_113824 "Vesicular inhibitory amino acid transport, Dictyostelium discoideum" + xref: Reactome:REACT_114586 "Vesicular inhibitory amino acid transport, Arabidopsis thaliana" GO:0005277 : acetylcholine transmembrane transporter activity + xref: Reactome:REACT_114068 "Loading of acetylcholine in synaptic vesicle, Gallus gallus" + xref: Reactome:REACT_113105 "Loading of acetylcholine in synaptic vesicle, Xenopus tropicalis" + xref: Reactome:REACT_112785 "Loading of acetylcholine in synaptic vesicle, Drosophila melanogaster" GO:0005309 : creatine:sodium symporter activity + xref: Reactome:REACT_115072 "Creatine transport across the plasma membrane, Staphylococcus aureus N315" + xref: Reactome:REACT_112702 "Creatine transport across the plasma membrane, Gallus gallus" + xref: Reactome:REACT_115159 "Creatine transport across the plasma membrane, Sus scrofa" + xref: Reactome:REACT_113563 "Creatine transport across the plasma membrane, Taeniopygia guttata" GO:0005310 : dicarboxylic acid transmembrane transporter activity - xref: Reactome:REACT_92805 "malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix], Bos taurus" + xref: Reactome:REACT_113778 "malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix], Arabidopsis thaliana" + xref: Reactome:REACT_113407 "malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix], Drosophila melanogaster" + xref: Reactome:REACT_112858 "malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix], Oryza sativa" + xref: Reactome:REACT_90846 "malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix], Bos taurus" GO:0005313 : L-glutamate transmembrane transporter activity - xref: Reactome:REACT_97115 "Vesicular glutamate transport, Dictyostelium discoideum" + xref: Reactome:REACT_113125 "Vesicular glutamate transport, Oryza sativa" + xref: Reactome:REACT_115281 "L-Glutamate loading of synaptic vesicle, Caenorhabditis elegans" + xref: Reactome:REACT_114619 "L-Glutamate loading of synaptic vesicle, Drosophila melanogaster" + xref: Reactome:REACT_113198 "Vesicular glutamate transport, Escherichia coli" + xref: Reactome:REACT_112266 "Vesicular glutamate transport, Staphylococcus aureus N315" + xref: Reactome:REACT_112417 "Vesicular glutamate transport, Arabidopsis thaliana" GO:0005314 : high-affinity glutamate transmembrane transporter activity + xref: Reactome:REACT_112875 "Glutamate transport, Drosophila melanogaster" + xref: Reactome:REACT_114169 "Glutamate transport, Staphylococcus aureus N315" GO:0005319 : lipid transporter activity - xref: Reactome:REACT_101503 "ABCA6, 10 and 12 in macrophage lipid homeostasis, Bos taurus" - xref: Reactome:REACT_77602 "ABCA6, 10 and 12 in macrophage lipid homeostasis, Taeniopygia guttata" - xref: Reactome:REACT_15303 "ABCA6, 10 and 12 in macrophage lipid homeostasis, Homo sapiens" - xref: Reactome:REACT_97936 "ABCA6, 10 and 12 in macrophage lipid homeostasis, Gallus gallus" + xref: Reactome:REACT_114808 "ABCAs mediate lipid efflux, Rattus norvegicus" + xref: Reactome:REACT_113910 "ABCAs mediate lipid efflux, Canis familiaris" + xref: Reactome:REACT_114929 "ABCAs mediate lipid influx, Bos taurus" + xref: Reactome:REACT_112420 "ABCAs mediate lipid efflux, Sus scrofa" + xref: Reactome:REACT_113696 "ABCAs mediate lipid influx, Taeniopygia guttata" + xref: Reactome:REACT_114336 "ABCAs mediate lipid efflux, Danio rerio" + xref: Reactome:REACT_112273 "ABCAs mediate lipid influx, Canis familiaris" + xref: Reactome:REACT_111169 "ABCAs mediate lipid influx, Homo sapiens" + xref: Reactome:REACT_111067 "ABCAs mediate lipid efflux, Homo sapiens" + xref: Reactome:REACT_115011 "ABCAs mediate lipid influx, Sus scrofa" + xref: Reactome:REACT_115076 "ABCAs mediate lipid influx, Gallus gallus" + xref: Reactome:REACT_114875 "ABCAs mediate lipid influx, Rattus norvegicus" + xref: Reactome:REACT_112793 "ABCAs mediate lipid influx, Drosophila melanogaster" + xref: Reactome:REACT_111998 "ABCAs mediate lipid efflux, Xenopus tropicalis" + xref: Reactome:REACT_115091 "ABCAs mediate lipid efflux, Gallus gallus" + xref: Reactome:REACT_114060 "ABCAs mediate lipid efflux, Bos taurus" + xref: Reactome:REACT_112990 "ABCAs mediate lipid efflux, Drosophila melanogaster" + xref: Reactome:REACT_112083 "ABCAs mediate lipid efflux, Mycobacterium tuberculosis" + xref: Reactome:REACT_112734 "ABCAs mediate lipid influx, Mus musculus" + xref: Reactome:REACT_113865 "ABCAs mediate lipid influx, Danio rerio" + xref: Reactome:REACT_112225 "ABCAs mediate lipid influx, Xenopus tropicalis" + xref: Reactome:REACT_114700 "ABCAs mediate lipid efflux, Mus musculus" + xref: Reactome:REACT_115251 "ABCAs mediate lipid efflux, Taeniopygia guttata" + xref: Reactome:REACT_113370 "ABCAs mediate lipid influx, Mycobacterium tuberculosis" GO:0005324 : long-chain fatty acid transporter activity - xref: Reactome:REACT_91468 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Rattus norvegicus" - xref: Reactome:REACT_34095 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Caenorhabditis elegans" - xref: Reactome:REACT_29426 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Taeniopygia guttata" - xref: Reactome:REACT_15322 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Homo sapiens" - xref: Reactome:REACT_105421 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Dictyostelium discoideum" - xref: Reactome:REACT_101477 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Drosophila melanogaster" - xref: Reactome:REACT_59791 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Sus scrofa" - xref: Reactome:REACT_78591 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Canis familiaris" - xref: Reactome:REACT_85267 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Gallus gallus" - xref: Reactome:REACT_106740 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Mus musculus" - xref: Reactome:REACT_34135 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Danio rerio" - xref: Reactome:REACT_34416 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Bos taurus" - xref: Reactome:REACT_101752 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Saccharomyces cerevisiae" - xref: Reactome:REACT_86284 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Xenopus tropicalis" + xref: Reactome:REACT_113806 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Mycobacterium tuberculosis" + xref: Reactome:REACT_15322 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Homo sapiens" + xref: Reactome:REACT_34416 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Bos taurus" + xref: Reactome:REACT_34135 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Danio rerio" + xref: Reactome:REACT_34095 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Caenorhabditis elegans" + xref: Reactome:REACT_101477 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Drosophila melanogaster" + xref: Reactome:REACT_106740 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Mus musculus" + xref: Reactome:REACT_95170 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Dictyostelium discoideum" + xref: Reactome:REACT_85267 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Gallus gallus" + xref: Reactome:REACT_59791 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Sus scrofa" + xref: Reactome:REACT_29426 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Taeniopygia guttata" + xref: Reactome:REACT_78591 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Canis familiaris" + xref: Reactome:REACT_91468 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Rattus norvegicus" + xref: Reactome:REACT_86284 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Xenopus tropicalis" + xref: Reactome:REACT_112344 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Escherichia coli" + xref: Reactome:REACT_101752 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Saccharomyces cerevisiae" GO:0005325 : peroxisomal fatty-acyl-CoA transporter activity - xref: Reactome:REACT_33050 "Peroxisomal uptake of very long-chain fatty acyl CoA, Taeniopygia guttata" + xref: Reactome:REACT_112629 "Peroxisomal uptake of very long-chain fatty acyl CoA, Escherichia coli" + xref: Reactome:REACT_113055 "Peroxisomal uptake of very long-chain fatty acyl CoA, Mycobacterium tuberculosis" GO:0005326 : neurotransmitter transporter activity - xref: Reactome:REACT_29685 "Uptake of Noradrenaline, Drosophila melanogaster" + xref: Reactome:REACT_114411 "Uptake of Noradrenaline, Danio rerio" + xref: Reactome:REACT_112831 "Uptake of Noradrenaline, Xenopus tropicalis" GO:0005337 : nucleoside transmembrane transporter activity - xref: Reactome:REACT_108665 "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1, Saccharomyces cerevisiae" - xref: Reactome:REACT_87112 "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1, Saccharomyces cerevisiae" - xref: Reactome:REACT_77332 "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2, Saccharomyces cerevisiae" - xref: Reactome:REACT_98724 "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2, Saccharomyces cerevisiae" + xref: Reactome:REACT_112137 "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2, Dictyostelium discoideum" + xref: Reactome:REACT_87106 "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1, Saccharomyces cerevisiae" + xref: Reactome:REACT_112369 "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1, Dictyostelium discoideum" + xref: Reactome:REACT_113840 "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2, Drosophila melanogaster" + xref: Reactome:REACT_81421 "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2, Saccharomyces cerevisiae" + xref: Reactome:REACT_113428 "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2, Dictyostelium discoideum" + xref: Reactome:REACT_115150 "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1, Drosophila melanogaster" + xref: Reactome:REACT_114976 "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2, Drosophila melanogaster" + xref: Reactome:REACT_112837 "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1, Drosophila melanogaster" + xref: Reactome:REACT_112717 "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1, Dictyostelium discoideum" + xref: Reactome:REACT_104920 "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1, Saccharomyces cerevisiae" + xref: Reactome:REACT_94316 "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2, Saccharomyces cerevisiae" GO:0005353 : fructose transmembrane transporter activity - xref: Reactome:REACT_80040 "Transport (influx) of fructose by GLUT5, Drosophila melanogaster" + xref: Reactome:REACT_114250 "Transport (influx) of fructose by GLUT5, Plasmodium falciparum" + xref: Reactome:REACT_113519 "Transport (influx) of fructose by GLUT5, Oryza sativa" + xref: Reactome:REACT_112097 "Transport (influx) of fructose by GLUT5, Mycobacterium tuberculosis" + xref: Reactome:REACT_114334 "Transport (influx) of fructose by GLUT5, Arabidopsis thaliana" + xref: Reactome:REACT_113496 "Transport (influx) of fructose by GLUT5, Dictyostelium discoideum" GO:0005355 : glucose transmembrane transporter activity + xref: Reactome:REACT_114814 "alpha-D-glucose (extracellular) <=> alpha-D-glucose (cytosol), Arabidopsis thaliana" + xref: Reactome:REACT_114865 "alpha-D-glucose (extracellular) <=> alpha-D-glucose (cytosol), Mycobacterium tuberculosis" + xref: Reactome:REACT_112687 "alpha-D-glucose (extracellular) <=> alpha-D-glucose (cytosol), Oryza sativa" + xref: Reactome:REACT_114521 "alpha-D-glucose (extracellular) <=> alpha-D-glucose (cytosol), Caenorhabditis elegans" + xref: Reactome:REACT_114420 "alpha-D-glucose (extracellular) <=> alpha-D-glucose (cytosol), Plasmodium falciparum" + xref: Reactome:REACT_113469 "alpha-D-glucose (extracellular) <=> alpha-D-glucose (cytosol), Dictyostelium discoideum" + xref: Reactome:REACT_114545 "alpha-D-glucose (extracellular) <=> alpha-D-glucose (cytosol), Drosophila melanogaster" GO:0005366 : myo-inositol:hydrogen symporter activity - xref: Reactome:REACT_98349 "HMIT co-transports myo-inositol with a proton, Sus scrofa" + xref: Reactome:REACT_84498 "HMIT co-transports myo-inositol with a proton, Sus scrofa" + xref: Reactome:REACT_113525 "HMIT co-transports myo-inositol with a proton, Dictyostelium discoideum" + xref: Reactome:REACT_114462 "HMIT co-transports myo-inositol with a proton, Gallus gallus" GO:0005375 : copper ion transmembrane transporter activity - xref: Reactome:REACT_99232 "Cellular copper transport is mediated by human copper transporter 1 hCTR1, Dictyostelium discoideum" - xref: Reactome:REACT_29863 "Cellular copper transport is mediated by human copper transporter 1 hCTR1, Schizosaccharomyces pombe" - xref: Reactome:REACT_107013 "Cellular copper transport is mediated by human copper transporter 1 hCTR1, Caenorhabditis elegans" - xref: Reactome:REACT_31800 "Cellular copper transport is mediated by human copper transporter 1 hCTR1, Drosophila melanogaster" - xref: Reactome:REACT_101681 "Cellular copper transport is mediated by human copper transporter 1 hCTR1, Saccharomyces cerevisiae" + xref: Reactome:REACT_82127 "Cellular copper transport is mediated by human copper transporter 1 hCTR1, Dictyostelium discoideum" GO:0005381 : iron ion transmembrane transporter activity + xref: Reactome:REACT_113775 "DCT1 (NRAMP2) mediates divalent iron uptake across the apical membrane of enterocytes, Staphylococcus aureus N315" GO:0005385 : zinc ion transmembrane transporter activity - xref: Reactome:REACT_86184 "ZnT1 mediates the efflux of zinc from the cell, Caenorhabditis elegans" - xref: Reactome:REACT_74679 "ZnT1 mediates the efflux of zinc from the cell, Dictyostelium discoideum" + xref: Reactome:REACT_113230 "ZnT7 transports zinc into the golgi apparatus, Arabidopsis thaliana" + xref: Reactome:REACT_88379 "ZnT1 mediates the efflux of zinc from the cell, Dictyostelium discoideum" + xref: Reactome:REACT_115265 "ZnT5 transports zinc into secretory granules in pancreatic beta cells, Oryza sativa" + xref: Reactome:REACT_113068 "ZnT5 transports zinc into secretory granules in pancreatic beta cells, Arabidopsis thaliana" + xref: Reactome:REACT_113286 "ZnT7 transports zinc into the golgi apparatus, Oryza sativa" GO:0005388 : calcium-transporting ATPase activity - xref: Reactome:REACT_92801 "PMCA extrusion of Ca2+, Schizosaccharomyces pombe" - xref: Reactome:REACT_28803 "PMCA extrusion of Ca2+, Saccharomyces cerevisiae" - xref: Reactome:REACT_79077 "PMCA extrusion of Ca2+, Dictyostelium discoideum" GO:0005391 : sodium:potassium-exchanging ATPase activity - synonym: "na+/K+-exchanging ATPase activity" EXACT [EC:3.6.3.9] GO:0005412 : glucose:sodium symporter activity + xref: Reactome:REACT_114364 "Co-transport (influx) of glucose and Na+ ions by SGLT2, Xenopus tropicalis" GO:0005432 : calcium:sodium antiporter activity + xref: Reactome:REACT_115279 "Na+/Ca2+ exchanger transport, Caenorhabditis elegans" + xref: Reactome:REACT_113595 "Na+/Ca2+ exchanger transport, Drosophila melanogaster" GO:0005452 : inorganic anion exchanger activity + xref: Reactome:REACT_114573 "Group 2 - Cl-/HCO3- exchanger transport, Plasmodium falciparum" + xref: Reactome:REACT_112953 "Na+-driven Cl-/HCO3- exchanger transport, Dictyostelium discoideum" + xref: Reactome:REACT_114293 "Group 2 - Cl-/HCO3- exchanger transport, Dictyostelium discoideum" + xref: Reactome:REACT_111979 "Cl-/HCO3- exchanger transport, Caenorhabditis elegans" + xref: Reactome:REACT_114173 "Cl-/HCO3- exchanger transport, Dictyostelium discoideum" GO:0005461 : UDP-glucuronic acid transmembrane transporter activity + xref: Reactome:REACT_113825 "UDP-glucuronate transport from the cytosol to ER lumen, Dictyostelium discoideum" GO:0005487 : nucleocytoplasmic transporter activity - xref: Reactome:REACT_91299 "GCK1:GKRP [cytosol] => GCK1:GKRP [nucleoplasm], Canis familiaris" + xref: Reactome:REACT_114315 "GCK1:GKRP [cytosol] => GCK1:GKRP [nucleoplasm], Xenopus tropicalis" GO:0005515 : protein binding - xref: Reactome:REACT_100108 "Formation of the IGF:IGFBP-5:ALS Complex, Bos taurus" - xref: Reactome:REACT_6923 "An anchoring protein, SARA, recruits R-SMAD, Homo sapiens" - xref: Reactome:REACT_90666 "An anchoring protein, SARA, recruits R-SMAD, Sus scrofa" - xref: Reactome:REACT_85975 "An anchoring protein, SARA, recruits R-SMAD, Danio rerio" - xref: Reactome:REACT_31648 "An anchoring protein, SARA, recruits R-SMAD, Mus musculus" - xref: Reactome:REACT_29941 "Formation of the IGF:IGFBP-4 Complex, Bos taurus" - xref: Reactome:REACT_102457 "An anchoring protein, SARA, recruits R-SMAD, Canis familiaris" - xref: Reactome:REACT_104488 "Formation of the IGF:IGFBP-3:ALS Complex, Bos taurus" - xref: Reactome:REACT_77120 "Formation of the IGF:IGFBP-2 Complex, Bos taurus" - xref: Reactome:REACT_33135 "An anchoring protein, SARA, recruits R-SMAD, Rattus norvegicus" - xref: Reactome:REACT_98807 "An anchoring protein, SARA, recruits R-SMAD, Bos taurus" - xref: Reactome:REACT_87187 "An anchoring protein, SARA, recruits R-SMAD, Xenopus tropicalis" - xref: Reactome:REACT_93596 "Formation of the IGF:IGFBP-6 Complex, Bos taurus" + xref: Reactome:REACT_33135 "An anchoring protein, SARA, recruits SMAD2/3, Rattus norvegicus" + xref: Reactome:REACT_31648 "An anchoring protein, SARA, recruits SMAD2/3, Mus musculus" + xref: Reactome:REACT_90666 "An anchoring protein, SARA, recruits SMAD2/3, Sus scrofa" + xref: Reactome:REACT_87652 "Formation of the IGF:IGFBP-5:ALS Complex, Bos taurus" + xref: Reactome:REACT_6923 "An anchoring protein, SARA, recruits SMAD2/3, Homo sapiens" + xref: Reactome:REACT_95647 "Formation of the IGF:IGFBP-3:ALS Complex, Bos taurus" + xref: Reactome:REACT_106168 "Formation of the IGF:IGFBP-2 Complex, Bos taurus" + xref: Reactome:REACT_98807 "An anchoring protein, SARA, recruits SMAD2/3, Bos taurus" + xref: Reactome:REACT_85975 "An anchoring protein, SARA, recruits SMAD2/3, Danio rerio" + xref: Reactome:REACT_104029 "Formation of the IGF:IGFBP-6 Complex, Bos taurus" + xref: Reactome:REACT_105895 "Formation of the IGF:IGFBP-4 Complex, Bos taurus" + xref: Reactome:REACT_87187 "An anchoring protein, SARA, recruits SMAD2/3, Xenopus tropicalis" + xref: Reactome:REACT_102457 "An anchoring protein, SARA, recruits SMAD2/3, Canis familiaris" GO:0005524 : ATP binding + xref: Reactome:REACT_115254 "Closing of Inward Rectifying, ATP-sensitive Potassium Channels (KATP channels), Drosophila melanogaster" GO:0005975 : carbohydrate metabolic process - xref: Reactome:REACT_101193 "Metabolism of carbohydrates, Sus scrofa" + xref: Reactome:REACT_90099 "Metabolism of carbohydrates, Sus scrofa" GO:0005977 : glycogen metabolic process - def: The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha(1->4) glycosidic linkage, joined together by alpha(1->6) glycosidic linkages. + def: The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages. GO:0005978 : glycogen biosynthetic process - xref: Reactome:REACT_110962 "Glycogen synthesis, Staphylococcus aureus N315" - xref: Reactome:REACT_89012 "Glycogen synthesis, Sus scrofa" + xref: Reactome:REACT_78900 "Glycogen synthesis, Sus scrofa" GO:0005980 : glycogen catabolic process - xref: Reactome:REACT_86564 "Glycogen breakdown (glycogenolysis), Dictyostelium discoideum" - xref: Reactome:REACT_92711 "Glycogen breakdown (glycogenolysis), Sus scrofa" - xref: Reactome:REACT_107066 "Glycogen breakdown (glycogenolysis), Staphylococcus aureus N315" + xref: Reactome:REACT_88320 "Glycogen breakdown (glycogenolysis), Dictyostelium discoideum" + xref: Reactome:REACT_79214 "Glycogen breakdown (glycogenolysis), Sus scrofa" GO:0006001 : fructose catabolic process - xref: Reactome:REACT_33549 "Fructose catabolism, Sus scrofa" + xref: Reactome:REACT_94187 "Fructose catabolism, Sus scrofa" GO:0006006 : glucose metabolic process - xref: Reactome:REACT_88065 "Glucose metabolism, Sus scrofa" - xref: Reactome:REACT_77853 "Glucose metabolism, Schizosaccharomyces pombe" + xref: Reactome:REACT_32548 "Glucose metabolism, Sus scrofa" + xref: Reactome:REACT_30713 "Glucose metabolism, Schizosaccharomyces pombe" GO:0006015 : 5-phosphoribose 1-diphosphate biosynthetic process - xref: Reactome:REACT_100133 "5-Phosphoribose 1-diphosphate biosynthesis, Sus scrofa" - xref: Reactome:REACT_107995 "5-Phosphoribose 1-diphosphate biosynthesis, Taeniopygia guttata" + xref: Reactome:REACT_105953 "5-Phosphoribose 1-diphosphate biosynthesis, Sus scrofa" + xref: Reactome:REACT_113394 "5-Phosphoribose 1-diphosphate biosynthesis, Xenopus tropicalis" GO:0006030 : chitin metabolic process - def: The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues. + def: The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. GO:0006031 : chitin biosynthetic process - def: The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues. + def: The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. GO:0006032 : chitin catabolic process - def: The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues. + def: The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. GO:0006034 : cuticle chitin metabolic process - def: The chemical reactions and pathways involving cuticle chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in cuticles. + def: The chemical reactions and pathways involving cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles. GO:0006035 : cuticle chitin biosynthetic process - def: The chemical reactions and pathways resulting in the formation of cuticle chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in cuticles. + def: The chemical reactions and pathways resulting in the formation of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles. GO:0006036 : cuticle chitin catabolic process - def: The chemical reactions and pathways resulting in the breakdown of cuticle chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in cuticles. + def: The chemical reactions and pathways resulting in the breakdown of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles. GO:0006037 : cell wall chitin metabolic process - def: The chemical reactions and pathways involving cell wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of cells. + def: The chemical reactions and pathways involving cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells. GO:0006038 : cell wall chitin biosynthetic process - def: The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of cells. + def: The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells. GO:0006039 : cell wall chitin catabolic process - def: The chemical reactions and pathways resulting in the breakdown of cell wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of cells. + def: The chemical reactions and pathways resulting in the breakdown of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells. GO:0006065 : UDP-glucuronate biosynthetic process - xref: Reactome:REACT_86979 "Formation of the active cofactor, UDP-glucuronate, Sus scrofa" + xref: Reactome:REACT_113773 "Formation of the active cofactor, UDP-glucuronate, Escherichia coli" + xref: Reactome:REACT_107830 "Formation of the active cofactor, UDP-glucuronate, Sus scrofa" GO:0006069 : ethanol oxidation - xref: Reactome:REACT_86838 "Ethanol oxidation, Saccharomyces cerevisiae" - xref: Reactome:REACT_92892 "Ethanol oxidation, Sus scrofa" - xref: Reactome:REACT_78153 "Ethanol oxidation, Schizosaccharomyces pombe" + xref: Reactome:REACT_114164 "Ethanol oxidation, Escherichia coli" + xref: Reactome:REACT_86318 "Ethanol oxidation, Sus scrofa" + xref: Reactome:REACT_113258 "Ethanol oxidation, Dictyostelium discoideum" GO:0006074 : (1->3)-beta-D-glucan metabolic process - name: 1,3-beta-D-glucan metabolic process + name: (1->3)-beta-D-glucan metabolic process - def: The chemical reactions and pathways involving beta-1,3 glucans, compounds composed of glucose residues linked by 1,3-beta-D-glucosidic bonds. + def: The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds. - synonym: "1,3-beta-glucan metabolism" EXACT [] + synonym: "1,3-beta-D-glucan metabolism" EXACT [] + synonym: "1,3-beta-D-glucan metabolic process" BROAD [GOC:tb] GO:0006075 : (1->3)-beta-D-glucan biosynthetic process - name: 1,3-beta-D-glucan biosynthetic process + name: (1->3)-beta-D-glucan biosynthetic process - def: The chemical reactions and pathways resulting in the formation of beta-1,3 glucans, compounds composed of glucose residues linked by 1,3-beta-D-glucosidic bonds. + def: The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds. - synonym: "1,3-beta-glucan biosynthetic process" BROAD [GOC:tb] + synonym: "1,3-beta-D-glucan biosynthetic process" EXACT [] GO:0006076 : (1->3)-beta-D-glucan catabolic process - name: 1,3-beta-D-glucan catabolic process + name: (1->3)-beta-D-glucan catabolic process - def: The chemical reactions and pathways resulting in the breakdown of beta-1,3 glucans. + def: The chemical reactions and pathways resulting in the breakdown of (1->3)-beta-D-glucans. - synonym: "1,3-beta-glucan catabolic process" BROAD [GOC:tb] + synonym: "1,3-beta-D-glucan catabolic process" EXACT [] GO:0006077 : (1->6)-beta-D-glucan metabolic process - name: 1,6-beta-glucan metabolic process + name: (1->6)-beta-D-glucan metabolic process - def: The chemical reactions and pathways involving beta-1,6 glucans, compounds composed of glucose residues linked by 1,6-beta-D-glucosidic bonds. + def: The chemical reactions and pathways involving (1->6)-beta-D-glucans, compounds composed of glucose residues linked by (1->6)-beta-D-glucosidic bonds. + synonym: "1,6-beta-glucan metabolic process" EXACT [] GO:0006078 : (1->6)-beta-D-glucan biosynthetic process - name: 1,6-beta-glucan biosynthetic process + name: (1->6)-beta-D-glucan biosynthetic process - def: The chemical reactions and pathways resulting in the formation of beta-1,6 glucans. + def: The chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans. + synonym: "1,6-beta-glucan biosynthetic process" EXACT [] GO:0006079 : (1->6)-beta-D-glucan catabolic process - name: 1,6-beta-glucan catabolic process + name: (1->6)-beta-D-glucan catabolic process - def: The chemical reactions and pathways resulting in the breakdown of beta-1,6 glucans. + def: The chemical reactions and pathways resulting in the breakdown of (1->6)-beta-D-glucans. - synonym: "1,6-beta-glucan catabolism" EXACT [] - synonym: "1,6-beta-glucan degradation" EXACT [] - synonym: "1,6-beta-glucan breakdown" EXACT [] + synonym: "1,6-beta-D-glucan breakdown" EXACT [] + synonym: "1,6-beta-D-glucan degradation" EXACT [] + synonym: "1,6-beta-D-glucan catabolism" EXACT [] + synonym: "1,6-beta-D-glucan catabolic process" EXACT [] GO:0006090 : pyruvate metabolic process - xref: Reactome:REACT_98406 "Pyruvate metabolism, Sus scrofa" - xref: Reactome:REACT_30108 "Pyruvate metabolism, Plasmodium falciparum" + xref: Reactome:REACT_101182 "Pyruvate metabolism, Sus scrofa" + xref: Reactome:REACT_112876 "Pyruvate metabolism, Drosophila melanogaster" GO:0006094 : gluconeogenesis - xref: Reactome:REACT_31854 "Gluconeogenesis, Sus scrofa" + xref: Reactome:REACT_78124 "Gluconeogenesis, Sus scrofa" GO:0006096 : glycolysis - xref: Reactome:REACT_110298 "Glycolysis, Sus scrofa" + xref: Reactome:REACT_99995 "Glycolysis, Sus scrofa" GO:0006098 : pentose-phosphate shunt - xref: Reactome:REACT_109960 "Pentose phosphate pathway (hexose monophosphate shunt), Sus scrofa" + xref: Reactome:REACT_81319 "Pentose phosphate pathway (hexose monophosphate shunt), Sus scrofa" GO:0006099 : tricarboxylic acid cycle - xref: Reactome:REACT_83444 "Citric acid cycle (TCA cycle), Sus scrofa" + xref: Reactome:REACT_89038 "Citric acid cycle (TCA cycle), Sus scrofa" GO:0006112 : energy reserve metabolic process - xref: Reactome:REACT_80630 "Integration of energy metabolism, Sus scrofa" + xref: Reactome:REACT_98844 "Integration of energy metabolism, Sus scrofa" GO:0006121 : mitochondrial electron transport, succinate to ubiquinone - xref: Reactome:REACT_91586 "Transfer of electrons through the succinate dehydrogenase complex, Saccharomyces cerevisiae" + xref: Reactome:REACT_88562 "Transfer of electrons through the succinate dehydrogenase complex, Saccharomyces cerevisiae" GO:0006122 : mitochondrial electron transport, ubiquinol to cytochrome c + xref: Reactome:REACT_113728 "Electron transfer from ubiquinol to cytochrome c of complex III, Bos taurus" + xref: Reactome:REACT_112720 "Electron transfer from ubiquinol to cytochrome c of complex III, Canis familiaris" + xref: Reactome:REACT_113468 "Electron transfer from ubiquinol to cytochrome c of complex III, Rattus norvegicus" + xref: Reactome:REACT_115341 "Electron transfer from ubiquinol to cytochrome c of complex III, Sus scrofa" + xref: Reactome:REACT_112947 "Electron transfer from ubiquinol to cytochrome c of complex III, Drosophila melanogaster" GO:0006123 : mitochondrial electron transport, cytochrome c to oxygen + xref: Reactome:REACT_115027 "Electron transfer from reduced cytochrome c to molecular oxygen, Rattus norvegicus" + xref: Reactome:REACT_113736 "Electron transfer from reduced cytochrome c to molecular oxygen, Canis familiaris" + xref: Reactome:REACT_113276 "Electron transfer from reduced cytochrome c to molecular oxygen, Bos taurus" + xref: Reactome:REACT_113311 "Electron transfer from reduced cytochrome c to molecular oxygen, Sus scrofa" GO:0006144 : purine base metabolic process - xref: Reactome:REACT_77402 "Purine metabolism, Sus scrofa" + xref: Reactome:REACT_80519 "Purine metabolism, Sus scrofa" GO:0006195 : purine nucleotide catabolic process - xref: Reactome:REACT_99545 "Purine catabolism, Sus scrofa" + xref: Reactome:REACT_113844 "Purine catabolism, Plasmodium falciparum" + xref: Reactome:REACT_95337 "Purine catabolism, Sus scrofa" GO:0006206 : pyrimidine base metabolic process - xref: Reactome:REACT_78271 "Pyrimidine metabolism, Sus scrofa" - xref: Reactome:REACT_32378 "Pyrimidine metabolism, Schizosaccharomyces pombe" + xref: Reactome:REACT_33296 "Pyrimidine metabolism, Sus scrofa" + xref: Reactome:REACT_30436 "Pyrimidine metabolism, Schizosaccharomyces pombe" GO:0006260 : DNA replication - xref: Reactome:REACT_85266 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Dictyostelium discoideum" + xref: Reactome:REACT_112472 "Activation of ATR in response to replication stress, Saccharomyces cerevisiae" + xref: Reactome:REACT_113703 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Gallus gallus" + xref: Reactome:REACT_33572 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Dictyostelium discoideum" GO:0006270 : DNA-dependent DNA replication initiation - xref: Reactome:REACT_85264 "DNA replication initiation, Sus scrofa" + xref: Reactome:REACT_77017 "DNA replication initiation, Sus scrofa" GO:0006271 : DNA strand elongation involved in DNA replication - xref: Reactome:REACT_88412 "DNA strand elongation, Sus scrofa" + xref: Reactome:REACT_95055 "DNA strand elongation, Sus scrofa" GO:0006281 : DNA repair - xref: Reactome:REACT_33728 "DNA Damage Reversal, Sus scrofa" - xref: Reactome:REACT_83599 "DNA Repair, Sus scrofa" - xref: Reactome:REACT_89358 "DNA Damage Reversal, Escherichia coli" - xref: Reactome:REACT_34272 "DNA Repair, Dictyostelium discoideum" + xref: Reactome:REACT_96052 "DNA Repair, Dictyostelium discoideum" + xref: Reactome:REACT_94204 "DNA Repair, Sus scrofa" + xref: Reactome:REACT_95050 "DNA Damage Reversal, Sus scrofa" GO:0006283 : transcription-coupled nucleotide-excision repair - xref: Reactome:REACT_109110 "Transcription-coupled NER (TC-NER), Dictyostelium discoideum" + xref: Reactome:REACT_81637 "Transcription-coupled NER (TC-NER), Dictyostelium discoideum" GO:0006284 : base-excision repair - xref: Reactome:REACT_85616 "Base Excision Repair, Dictyostelium discoideum" + xref: Reactome:REACT_91955 "Base Excision Repair, Dictyostelium discoideum" GO:0006286 : base-excision repair, base-free sugar-phosphate removal - xref: Reactome:REACT_86232 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Sus scrofa" + xref: Reactome:REACT_85754 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Sus scrofa" GO:0006288 : base-excision repair, DNA ligation - xref: Reactome:REACT_80904 "Ligation of DNA at sites of patch replacement, Sus scrofa" + xref: Reactome:REACT_31800 "Ligation of DNA at sites of patch replacement, Sus scrofa" GO:0006289 : nucleotide-excision repair - xref: Reactome:REACT_105090 "Nucleotide Excision Repair, Sus scrofa" + xref: Reactome:REACT_30685 "Nucleotide Excision Repair, Sus scrofa" GO:0006293 : nucleotide-excision repair, preincision complex stabilization - xref: Reactome:REACT_96915 "Binding of ERCC1-XPF to preincision complex, Saccharomyces cerevisiae" + xref: Reactome:REACT_114006 "Binding of ERCC1-XPF to preincision complex, Caenorhabditis elegans" + xref: Reactome:REACT_28578 "Binding of ERCC1-XPF to preincision complex, Saccharomyces cerevisiae" GO:0006294 : nucleotide-excision repair, preincision complex assembly - xref: Reactome:REACT_107925 "Recruitment of repair factors to form preincision complex, Bos taurus" + xref: Reactome:REACT_112711 "Recruitment of repair factors to form preincision complex, Xenopus tropicalis" GO:0006296 : nucleotide-excision repair, DNA incision, 5'-to lesion - xref: Reactome:REACT_91600 "5'-incision of DNA by ERCC1-XPF in GG-NER, Bos taurus" + xref: Reactome:REACT_112122 "5'-incision of DNA by ERCC1-XPF in GG-NER, Xenopus tropicalis" GO:0006303 : double-strand break repair via nonhomologous end joining + xref: Reactome:REACT_114794 "Nonhomologous End-joining (NHEJ), Xenopus tropicalis" GO:0006307 : DNA dealkylation involved in DNA repair - xref: Reactome:REACT_102469 "MGMT/hAGT mediated DNA Damage Reversal, Escherichia coli" - xref: Reactome:REACT_87264 "MGMT/hAGT mediated DNA Damage Reversal, Sus scrofa" + xref: Reactome:REACT_108289 "MGMT/hAGT mediated DNA Damage Reversal, Sus scrofa" + xref: Reactome:REACT_113979 "ABH2 mediated Reversal of Alkylation Damage, Arabidopsis thaliana" + xref: Reactome:REACT_113126 "ABH2 mediated Reversal of Alkylation Damage, Oryza sativa" GO:0006309 : DNA fragmentation involved in apoptotic nuclear change + xref: Reactome:REACT_113418 "Apoptosis induced DNA fragmentation, Plasmodium falciparum" GO:0006360 : transcription from RNA polymerase I promoter - xref: Reactome:REACT_96840 "RNA Polymerase I Transcription, Sus scrofa" + xref: Reactome:REACT_77153 "RNA Polymerase I Transcription, Sus scrofa" GO:0006361 : transcription initiation from RNA polymerase I promoter - xref: Reactome:REACT_85489 "RNA Polymerase I Promoter Escape, Bos taurus" - xref: Reactome:REACT_29994 "RNA Polymerase I Promoter Clearance, Dictyostelium discoideum" - xref: Reactome:REACT_106811 "RNA Polymerase I Transcription Initiation, Sus scrofa" - xref: Reactome:REACT_96041 "RNA Polymerase I Promoter Clearance, Sus scrofa" - xref: Reactome:REACT_109032 "RNA Polymerase I Promoter Opening, Sus scrofa" - xref: Reactome:REACT_89661 "RNA Polymerase I Promoter Escape, Canis familiaris" + xref: Reactome:REACT_28247 "RNA Polymerase I Transcription Initiation, Sus scrofa" + xref: Reactome:REACT_112095 "RNA Polymerase I Promoter Opening, Rattus norvegicus" + xref: Reactome:REACT_80295 "RNA Polymerase I Promoter Opening, Sus scrofa" + xref: Reactome:REACT_112001 "RNA Polymerase I Promoter Escape, Oryza sativa" + xref: Reactome:REACT_113247 "RNA Polymerase I Promoter Escape, Gallus gallus" + xref: Reactome:REACT_28672 "RNA Polymerase I Promoter Clearance, Sus scrofa" + xref: Reactome:REACT_108556 "RNA Polymerase I Promoter Clearance, Dictyostelium discoideum" + xref: Reactome:REACT_114933 "RNA Polymerase I Promoter Escape, Rattus norvegicus" GO:0006362 : transcription elongation from RNA polymerase I promoter + xref: Reactome:REACT_115044 "RNA Polymerase I Chain Elongation, Gallus gallus" + xref: Reactome:REACT_112721 "RNA Polymerase I Chain Elongation, Oryza sativa" GO:0006363 : termination of RNA polymerase I transcription + xref: Reactome:REACT_113509 "RNA Polymerase I Transcription Termination, Gallus gallus" GO:0006368 : transcription elongation from RNA polymerase II promoter + xref: Reactome:REACT_112630 "Formation of RNA Pol II elongation complex, Schizosaccharomyces pombe" + xref: Reactome:REACT_115524 "Formation of RNA Pol II elongation complex, Danio rerio" + xref: Reactome:REACT_112408 "Formation of RNA Pol II elongation complex, Drosophila melanogaster" + xref: Reactome:REACT_113325 "Formation of RNA Pol II elongation complex, Caenorhabditis elegans" GO:0006369 : termination of RNA polymerase II transcription - xref: Reactome:REACT_32387 "RNA Polymerase II Transcription Termination, Sus scrofa" - xref: Reactome:REACT_81555 "Cleavage of Growing Transcript in the Termination Region, Sus scrofa" + xref: Reactome:REACT_113157 "RNA Polymerase II Transcription Termination, Arabidopsis thaliana" + xref: Reactome:REACT_114998 "RNA Polymerase II Transcription Termination, Danio rerio" + xref: Reactome:REACT_114593 "Cleavage of Growing Transcript in the Termination Region, Danio rerio" + xref: Reactome:REACT_112978 "RNA Polymerase II Transcription Termination, Drosophila melanogaster" + xref: Reactome:REACT_115466 "Cleavage of Growing Transcript in the Termination Region, Arabidopsis thaliana" + xref: Reactome:REACT_113171 "Cleavage of Growing Transcript in the Termination Region, Drosophila melanogaster" GO:0006370 : mRNA capping - xref: Reactome:REACT_87402 "mRNA Capping, Dictyostelium discoideum" + xref: Reactome:REACT_96579 "mRNA Capping, Dictyostelium discoideum" + xref: Reactome:REACT_114999 "mRNA Capping, Plasmodium falciparum" GO:0006382 : adenosine to inosine editing + xref: Reactome:REACT_112897 "mRNA Editing: A to I Conversion, Oryza sativa" + xref: Reactome:REACT_112523 "mRNA Editing: A to I Conversion, Saccharomyces cerevisiae" + xref: Reactome:REACT_112594 "mRNA Editing: A to I Conversion, Caenorhabditis elegans" + xref: Reactome:REACT_112784 "mRNA Editing: A to I Conversion, Arabidopsis thaliana" + xref: Reactome:REACT_113069 "mRNA Editing: A to I Conversion, Schizosaccharomyces pombe" GO:0006383 : transcription from RNA polymerase III promoter + xref: Reactome:REACT_114988 "RNA Polymerase III Simple Start Sequence Initiation At Type 3 Promoters, Drosophila melanogaster" + xref: Reactome:REACT_113692 "RNA Polymerase III Abortive Initiation At Type 2 Open Promoters, Dictyostelium discoideum" + xref: Reactome:REACT_112623 "RNA Polymerase III Abortive Initiation At Type 3 Open Promoters, Drosophila melanogaster" + xref: Reactome:REACT_112804 "RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters, Dictyostelium discoideum" GO:0006397 : mRNA processing + xref: Reactome:REACT_114358 "Processing of Capped Intronless Pre-mRNA, Schizosaccharomyces pombe" + xref: Reactome:REACT_115262 "Processing of Capped Intronless Pre-mRNA, Arabidopsis thaliana" + xref: Reactome:REACT_113864 "Processing of Capped Intronless Pre-mRNA, Saccharomyces cerevisiae" GO:0006405 : RNA export from nucleus - xref: Reactome:REACT_28678 "Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC, Drosophila melanogaster" - xref: Reactome:REACT_77395 "Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC, Drosophila melanogaster" - xref: Reactome:REACT_109623 "Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC, Drosophila melanogaster" + xref: Reactome:REACT_114184 "Recruitment of TAP to the EJC, Drosophila melanogaster" GO:0006406 : mRNA export from nucleus - xref: Reactome:REACT_100049 "Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC, Drosophila melanogaster" - xref: Reactome:REACT_102246 "Transport of the export-competent complex through the NPC, Xenopus tropicalis" - xref: Reactome:REACT_92048 "Release of the SLBP independent Histone mRNA from the NPC, Drosophila melanogaster" - xref: Reactome:REACT_91579 "Release from the NPC and Disassembly of the mRNP, Drosophila melanogaster" - xref: Reactome:REACT_109313 "Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex, Drosophila melanogaster" - xref: Reactome:REACT_96477 "Transport of Mature mRNAs Derived from Intronless Transcripts, Drosophila melanogaster" + xref: Reactome:REACT_114603 "Docking of Mature Histone mRNA complex:TAP at the NPC, Danio rerio" + xref: Reactome:REACT_113695 "Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC, Danio rerio" + xref: Reactome:REACT_112057 "Docking of Mature Replication Dependent Histone mRNA with the NPC, Danio rerio" GO:0006412 : translation - xref: Reactome:REACT_84182 "Translation, Sus scrofa" + xref: Reactome:REACT_100338 "Translation, Sus scrofa" GO:0006413 : translational initiation + xref: Reactome:REACT_101789 "Eukaryotic Translation Initiation, Gallus gallus" + xref: Reactome:REACT_104290 "Eukaryotic Translation Initiation, Xenopus tropicalis" + xref: Reactome:REACT_2159 "Eukaryotic Translation Initiation, Homo sapiens" + xref: Reactome:REACT_29447 "Eukaryotic Translation Initiation, Dictyostelium discoideum" + xref: Reactome:REACT_30389 "Eukaryotic Translation Initiation, Oryza sativa" + xref: Reactome:REACT_33969 "Eukaryotic Translation Initiation, Caenorhabditis elegans" + xref: Reactome:REACT_34354 "Eukaryotic Translation Initiation, Taeniopygia guttata" + xref: Reactome:REACT_77252 "Eukaryotic Translation Initiation, Drosophila melanogaster" + xref: Reactome:REACT_79705 "Eukaryotic Translation Initiation, Rattus norvegicus" + xref: Reactome:REACT_85780 "Eukaryotic Translation Initiation, Bos taurus" + xref: Reactome:REACT_88031 "Eukaryotic Translation Initiation, Schizosaccharomyces pombe" + xref: Reactome:REACT_91066 "Eukaryotic Translation Initiation, Arabidopsis thaliana" + xref: Reactome:REACT_95293 "Eukaryotic Translation Initiation, Plasmodium falciparum" + xref: Reactome:REACT_95552 "Eukaryotic Translation Initiation, Mus musculus" + xref: Reactome:REACT_95685 "Eukaryotic Translation Initiation, Canis familiaris" + xref: Reactome:REACT_97707 "Eukaryotic Translation Initiation, Sus scrofa" + xref: Reactome:REACT_98138 "Eukaryotic Translation Initiation, Saccharomyces cerevisiae" + xref: Reactome:REACT_99004 "Eukaryotic Translation Initiation, Danio rerio" GO:0006414 : translational elongation - xref: Reactome:REACT_97803 "Eukaryotic Translation Elongation, Dictyostelium discoideum" - xref: Reactome:REACT_109322 "Eukaryotic Translation Elongation, Sus scrofa" + xref: Reactome:REACT_31079 "Eukaryotic Translation Elongation, Sus scrofa" + xref: Reactome:REACT_100207 "Eukaryotic Translation Elongation, Dictyostelium discoideum" GO:0006415 : translational termination - xref: Reactome:REACT_106717 "Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex, Dictyostelium discoideum" + xref: Reactome:REACT_114287 "Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex, Gallus gallus" + xref: Reactome:REACT_112632 "Eukaryotic Translation Termination, Rattus norvegicus" + xref: Reactome:REACT_115309 "GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex, Bos taurus" + xref: Reactome:REACT_33545 "Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex, Dictyostelium discoideum" + xref: Reactome:REACT_115424 "Eukaryotic Translation Termination, Bos taurus" + xref: Reactome:REACT_113540 "GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex, Gallus gallus" + xref: Reactome:REACT_112381 "GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex, Gallus gallus" + xref: Reactome:REACT_115292 "Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex, Rattus norvegicus" + xref: Reactome:REACT_114142 "Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex, Bos taurus" + xref: Reactome:REACT_112559 "GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex, Rattus norvegicus" + xref: Reactome:REACT_114807 "Eukaryotic Translation Termination, Gallus gallus" GO:0006418 : tRNA aminoacylation for protein translation - xref: Reactome:REACT_104322 "Cytosolic tRNA aminoacylation, Sus scrofa" - xref: Reactome:REACT_90554 "tRNA Aminoacylation, Sus scrofa" + xref: Reactome:REACT_100416 "Cytosolic tRNA aminoacylation, Sus scrofa" + xref: Reactome:REACT_81425 "tRNA Aminoacylation, Sus scrofa" GO:0006488 : dolichol-linked oligosaccharide biosynthetic process - xref: Reactome:REACT_79420 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein, Caenorhabditis elegans" + xref: Reactome:REACT_30432 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein, Caenorhabditis elegans" GO:0006501 : C-terminal protein lipidation - xref: Reactome:REACT_87521 "Post-translational modification: synthesis of GPI-anchored proteins, Sus scrofa" + xref: Reactome:REACT_106946 "Post-translational modification: synthesis of GPI-anchored proteins, Sus scrofa" GO:0006548 : histidine catabolic process - xref: Reactome:REACT_102083 "Histidine catabolism, Sus scrofa" + xref: Reactome:REACT_103575 "Histidine catabolism, Sus scrofa" GO:0006554 : lysine catabolic process - xref: Reactome:REACT_100380 "Lysine catabolism, Sus scrofa" + xref: Reactome:REACT_113274 "Lysine catabolism, Escherichia coli" + xref: Reactome:REACT_88111 "Lysine catabolism, Sus scrofa" GO:0006559 : L-phenylalanine catabolic process - xref: Reactome:REACT_89997 "Phenylalanine and tyrosine catabolism, Sus scrofa" + xref: Reactome:REACT_98835 "Phenylalanine and tyrosine catabolism, Sus scrofa" GO:0006569 : tryptophan catabolic process - xref: Reactome:REACT_103644 "Tryptophan catabolism, Sus scrofa" + xref: Reactome:REACT_76959 "Tryptophan catabolism, Sus scrofa" GO:0006600 : creatine metabolic process - xref: Reactome:REACT_90153 "Creatine metabolism, Sus scrofa" + xref: Reactome:REACT_112303 "Creatine metabolism, Staphylococcus aureus N315" + xref: Reactome:REACT_87835 "Creatine metabolism, Sus scrofa" GO:0006629 : lipid metabolic process - xref: Reactome:REACT_98052 "Lipid digestion, mobilization, and transport, Caenorhabditis elegans" + xref: Reactome:REACT_114669 "Lipid digestion, mobilization, and transport, Staphylococcus aureus N315" + xref: Reactome:REACT_87884 "Lipid digestion, mobilization, and transport, Caenorhabditis elegans" GO:0006635 : fatty acid beta-oxidation - xref: Reactome:REACT_88198 "Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA, Bos taurus" - xref: Reactome:REACT_76961 "Mitochondrial Fatty Acid Beta-Oxidation, Sus scrofa" - xref: Reactome:REACT_82039 "dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA, Caenorhabditis elegans" - xref: Reactome:REACT_110665 "Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA, Mycobacterium tuberculosis" - xref: Reactome:REACT_51199 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Bos taurus" + xref: Reactome:REACT_113891 "Mitochondrial Fatty Acid Beta-Oxidation, Staphylococcus aureus N315" + xref: Reactome:REACT_81660 "Mitochondrial Fatty Acid Beta-Oxidation, Sus scrofa" + xref: Reactome:REACT_34789 "Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA, Bos taurus" + xref: Reactome:REACT_99180 "dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA, Caenorhabditis elegans" + xref: Reactome:REACT_99776 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Bos taurus" GO:0006665 : sphingolipid metabolic process + xref: Reactome:REACT_112370 "Sphingolipid metabolism, Escherichia coli" GO:0006692 : prostanoid metabolic process + xref: Reactome:REACT_113225 "Prostanoid metabolism, Mycobacterium tuberculosis" GO:0006695 : cholesterol biosynthetic process - xref: Reactome:REACT_90089 "Cholesterol biosynthesis, Schizosaccharomyces pombe" + xref: Reactome:REACT_105508 "Cholesterol biosynthesis, Schizosaccharomyces pombe" GO:0006699 : bile acid biosynthetic process - xref: Reactome:REACT_31259 "Synthesis of bile acids and bile salts via 27-hydroxycholesterol, Caenorhabditis elegans" - xref: Reactome:REACT_104896 "Synthesis of bile acids and bile salts via 27-hydroxycholesterol, Schizosaccharomyces pombe" - xref: Reactome:REACT_89285 "Synthesis of bile acids and bile salts via 24-hydroxycholesterol, Schizosaccharomyces pombe" + xref: Reactome:REACT_112535 "Synthesis of bile acids and bile salts via 24-hydroxycholesterol, Dictyostelium discoideum" + xref: Reactome:REACT_113889 "Synthesis of bile acids and bile salts, Plasmodium falciparum" + xref: Reactome:REACT_113534 "Synthesis of bile acids and bile salts via 27-hydroxycholesterol, Mycobacterium tuberculosis" + xref: Reactome:REACT_114349 "Synthesis of bile acids and bile salts via 27-hydroxycholesterol, Arabidopsis thaliana" + xref: Reactome:REACT_114625 "Synthesis of bile acids and bile salts via 27-hydroxycholesterol, Dictyostelium discoideum" + xref: Reactome:REACT_113599 "Synthesis of bile acids and bile salts via 27-hydroxycholesterol, Oryza sativa" + xref: Reactome:REACT_113154 "Synthesis of bile acids and bile salts via 24-hydroxycholesterol, Oryza sativa" + xref: Reactome:REACT_114646 "Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol, Plasmodium falciparum" GO:0006700 : C21-steroid hormone biosynthetic process - xref: Reactome:REACT_84578 "Pregnenolone biosynthesis, Escherichia coli" - xref: Reactome:REACT_92167 "Pregnenolone biosynthesis, Schizosaccharomyces pombe" + xref: Reactome:REACT_113158 "Pregnenolone biosynthesis, Dictyostelium discoideum" + xref: Reactome:REACT_115282 "Pregnenolone biosynthesis, Oryza sativa" + xref: Reactome:REACT_115412 "Pregnenolone biosynthesis, Arabidopsis thaliana" GO:0006702 : androgen biosynthetic process - xref: Reactome:REACT_104244 "Androgen biosynthesis, Caenorhabditis elegans" - xref: Reactome:REACT_32608 "Androgen biosynthesis, Dictyostelium discoideum" + xref: Reactome:REACT_112163 "Androgen biosynthesis, Escherichia coli" + xref: Reactome:REACT_98944 "Androgen biosynthesis, Dictyostelium discoideum" + xref: Reactome:REACT_112753 "Androgen biosynthesis, Mycobacterium tuberculosis" GO:0006704 : glucocorticoid biosynthetic process - xref: Reactome:REACT_96615 "Glucocorticoid biosynthesis, Caenorhabditis elegans" + xref: Reactome:REACT_112672 "Glucocorticoid biosynthesis, Plasmodium falciparum" + xref: Reactome:REACT_113066 "Glucocorticoid biosynthesis, Escherichia coli" GO:0006705 : mineralocorticoid biosynthetic process - xref: Reactome:REACT_107471 "Mineralocorticoid biosynthesis, Caenorhabditis elegans" + xref: Reactome:REACT_112957 "Mineralocorticoid biosynthesis, Escherichia coli" + xref: Reactome:REACT_113805 "Mineralocorticoid biosynthesis, Mycobacterium tuberculosis" GO:0006740 : NADPH regeneration + xref: Reactome:REACT_115247 "NADPH regeneration, Oryza sativa" + xref: Reactome:REACT_113557 "NADPH regeneration, Arabidopsis thaliana" + xref: Reactome:REACT_114218 "NADPH regeneration, Plasmodium falciparum" GO:0006754 : ATP biosynthetic process - xref: Reactome:REACT_94502 "ATP is synthesized from ADP and Pi by ATPase, Taeniopygia guttata" - xref: Reactome:REACT_85973 "ADP and Pi bind to ATPase, Taeniopygia guttata" GO:0006769 : nicotinamide metabolic process - xref: Reactome:REACT_81936 "Nicotinamide salvaging, Plasmodium falciparum" + xref: Reactome:REACT_104665 "Nicotinamide salvaging, Plasmodium falciparum" GO:0006778 : porphyrin-containing compound metabolic process + xref: Reactome:REACT_112552 "Metabolism of porphyrins, Caenorhabditis elegans" GO:0006789 : bilirubin conjugation - xref: Reactome:REACT_85610 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Gallus gallus" - xref: Reactome:REACT_96677 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Sus scrofa" - xref: Reactome:REACT_96026 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Xenopus tropicalis" - xref: Reactome:REACT_94974 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Drosophila melanogaster" + xref: Reactome:REACT_96239 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Sus scrofa" + xref: Reactome:REACT_113946 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Caenorhabditis elegans" GO:0006805 : xenobiotic metabolic process - xref: Reactome:REACT_102277 "Biological oxidations, Sus scrofa" - xref: Reactome:REACT_99732 "Conjugation of phenylacetate with glutamine, Taeniopygia guttata" - xref: Reactome:REACT_86211 "Conjugation of phenylacetate with glutamine, Danio rerio" - xref: Reactome:REACT_89442 "Phase II conjugation, Sus scrofa" - xref: Reactome:REACT_97512 "Conjugation of benzoate with glycine, Gallus gallus" - xref: Reactome:REACT_79356 "Conjugation of phenylacetate with glutamine, Gallus gallus" - xref: Reactome:REACT_103704 "Conjugation of salicylate with glycine, Gallus gallus" - xref: Reactome:REACT_83267 "Conjugation of benzoate with glycine, Taeniopygia guttata" - xref: Reactome:REACT_81348 "Amino Acid conjugation, Taeniopygia guttata" - xref: Reactome:REACT_28583 "Conjugation of carboxylic acids, Taeniopygia guttata" - xref: Reactome:REACT_98034 "Conjugation of carboxylic acids, Gallus gallus" - xref: Reactome:REACT_29864 "Conjugation of salicylate with glycine, Taeniopygia guttata" - xref: Reactome:REACT_102079 "Phase 1 - Functionalization of compounds, Sus scrofa" - xref: Reactome:REACT_94547 "Amino Acid conjugation, Gallus gallus" + xref: Reactome:REACT_112180 "Conjugation of phenylacetate with glutamine, Dictyostelium discoideum" + xref: Reactome:REACT_78563 "Phase 1 - Functionalization of compounds, Sus scrofa" + xref: Reactome:REACT_112300 "Amino Acid conjugation, Dictyostelium discoideum" + xref: Reactome:REACT_89167 "Phase II conjugation, Sus scrofa" + xref: Reactome:REACT_112424 "Conjugation of salicylate with glycine, Dictyostelium discoideum" + xref: Reactome:REACT_114132 "Conjugation of benzoate with glycine, Dictyostelium discoideum" + xref: Reactome:REACT_115368 "Conjugation of carboxylic acids, Dictyostelium discoideum" + xref: Reactome:REACT_115263 "Phase 1 - Functionalization of compounds, Escherichia coli" + xref: Reactome:REACT_110976 "Biological oxidations, Sus scrofa" GO:0006833 : water transport - xref: Reactome:REACT_100528 "Aquaporin-mediated transport, Saccharomyces cerevisiae" - xref: Reactome:REACT_98054 "Regulation of Water Balance by Renal Aquaporins, Arabidopsis thaliana" - xref: Reactome:REACT_88899 "Regulation of Water Balance by Renal Aquaporins, Oryza sativa" - xref: Reactome:REACT_28487 "Aquaporin-mediated transport, Arabidopsis thaliana" - xref: Reactome:REACT_101266 "Aquaporin-mediated transport, Oryza sativa" - xref: Reactome:REACT_77446 "Passive Transport by Aquaporins, Arabidopsis thaliana" - xref: Reactome:REACT_94824 "Passive Transport by Aquaporins, Oryza sativa" + xref: Reactome:REACT_112337 "Passive Transport by Aquaporins, Escherichia coli" + xref: Reactome:REACT_108009 "Aquaporin-mediated transport, Saccharomyces cerevisiae" + xref: Reactome:REACT_113611 "Passive Transport by Aquaporins, Drosophila melanogaster" GO:0006853 : carnitine shuttle - xref: Reactome:REACT_77467 "Import of palmitoyl-CoA into the mitochondrial matrix, Sus scrofa" - xref: Reactome:REACT_108710 "Import of palmitoyl-CoA into the mitochondrial matrix, Plasmodium falciparum" + xref: Reactome:REACT_84030 "Import of palmitoyl-CoA into the mitochondrial matrix, Sus scrofa" GO:0006865 : amino acid transport + xref: Reactome:REACT_115423 "Amino acid transport across the plasma membrane, Saccharomyces cerevisiae" + xref: Reactome:REACT_112073 "Amino acid transport across the plasma membrane, Mycobacterium tuberculosis" GO:0006879 : cellular iron ion homeostasis - xref: Reactome:REACT_95122 "Iron uptake and transport, Dictyostelium discoideum" + xref: Reactome:REACT_113782 "Iron uptake and transport, Staphylococcus aureus N315" + xref: Reactome:REACT_92578 "Iron uptake and transport, Dictyostelium discoideum" GO:0006888 : ER to Golgi vesicle-mediated transport - xref: Reactome:REACT_97917 "ER to Golgi Transport, Caenorhabditis elegans" GO:0006892 : post-Golgi vesicle-mediated transport - xref: Reactome:REACT_34456 "trans-Golgi Network Vesicle Budding, Saccharomyces cerevisiae" GO:0006898 : receptor-mediated endocytosis + xref: Reactome:REACT_114157 "chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex, Xenopus tropicalis" + xref: Reactome:REACT_114755 "LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent), Taeniopygia guttata" + xref: Reactome:REACT_114861 "LDL + LDLR => LDL:LDLR complex, Taeniopygia guttata" + xref: Reactome:REACT_113143 "LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane], Taeniopygia guttata" + xref: Reactome:REACT_115520 "LDL-mediated lipid transport, Drosophila melanogaster" + xref: Reactome:REACT_115471 "LDLR [endosome membrane] => LDLR [plasma membrane], Caenorhabditis elegans" + xref: Reactome:REACT_112262 "LDLR [endosome membrane] => LDLR [plasma membrane], Taeniopygia guttata" + xref: Reactome:REACT_111177 "Movement of clathrin coated vesicles into early endosome, Homo sapiens" + xref: Reactome:REACT_113715 "LDLR [endosome membrane] => LDLR [plasma membrane], Drosophila melanogaster" + xref: Reactome:REACT_114061 "LDLR:LDL complex => LDLR + LDL, Taeniopygia guttata" + xref: Reactome:REACT_115278 "LDL-mediated lipid transport, Caenorhabditis elegans" GO:0006915 : apoptosis - xref: Reactome:REACT_101916 "Apoptosis, Saccharomyces cerevisiae" + xref: Reactome:REACT_111964 "NRAGE signals death through JNK, Dictyostelium discoideum" + xref: Reactome:REACT_28087 "Apoptosis, Saccharomyces cerevisiae" GO:0006936 : muscle contraction - xref: Reactome:REACT_97034 "Smooth Muscle Contraction, Drosophila melanogaster" - xref: Reactome:REACT_90741 "Smooth Muscle Contraction, Dictyostelium discoideum" - xref: Reactome:REACT_80035 "Smooth Muscle Contraction, Caenorhabditis elegans" + xref: Reactome:REACT_92442 "Smooth Muscle Contraction, Dictyostelium discoideum" GO:0006956 : complement activation - xref: Reactome:REACT_84310 "Activation of C3 and C5, Xenopus tropicalis" GO:0006958 : complement activation, classical pathway - xref: Reactome:REACT_86322 "Classical antibody-mediated complement activation, Taeniopygia guttata" - xref: Reactome:REACT_90437 "Classical antibody-mediated complement activation, Canis familiaris" - xref: Reactome:REACT_86543 "Classical antibody-mediated complement activation, Danio rerio" - xref: Reactome:REACT_91430 "Classical antibody-mediated complement activation, Gallus gallus" GO:0006977 : DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest - xref: Reactome:REACT_99984 "p53-Dependent G1 DNA Damage Response, Dictyostelium discoideum" - xref: Reactome:REACT_104601 "p53-Dependent G1 DNA Damage Response, Sus scrofa" + xref: Reactome:REACT_33731 "p53-Dependent G1 DNA Damage Response, Dictyostelium discoideum" + xref: Reactome:REACT_97071 "p53-Dependent G1 DNA Damage Response, Sus scrofa" GO:0007004 : telomere maintenance via telomerase - xref: Reactome:REACT_77982 "Elongation Of The Telomeric Chromosome End, Sus scrofa" - xref: Reactome:REACT_33186 "Recruitment of Telomerase RNP to the Telomeric Chromosome End, Saccharomyces cerevisiae" - xref: Reactome:REACT_110598 "Alignment Of The RNA Template On The Telomeric Chromosome End, Sus scrofa" - xref: Reactome:REACT_109384 "Disassociation of Telomerase RNP and the Chromosome End, Saccharomyces cerevisiae" - xref: Reactome:REACT_84958 "Elongation of Extended Telomeric Chromosome End, Saccharomyces cerevisiae" - xref: Reactome:REACT_30302 "Elongation Of The Telomeric Chromosome End, Dictyostelium discoideum" - xref: Reactome:REACT_102517 "Disassociation of Telomerase RNP and the Chromosome End, Dictyostelium discoideum" - xref: Reactome:REACT_101432 "Recruitment of Telomerase RNP to the Telomeric Chromosome End, Dictyostelium discoideum" - xref: Reactome:REACT_86897 "Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End, Dictyostelium discoideum" - xref: Reactome:REACT_32224 "Elongation of Extended Telomeric Chromosome End, Dictyostelium discoideum" - xref: Reactome:REACT_95862 "Recruitment of Telomerase RNP to the Telomeric Chromosome End, Sus scrofa" - xref: Reactome:REACT_30646 "Alignment Of The RNA Template On The Telomeric Chromosome End, Saccharomyces cerevisiae" - xref: Reactome:REACT_93266 "Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End, Saccharomyces cerevisiae" - xref: Reactome:REACT_105068 "Alignment Of The RNA Template On The Telomeric Chromosome End, Dictyostelium discoideum" - xref: Reactome:REACT_98714 "Telomere Extension By Telomerase, Dictyostelium discoideum" - xref: Reactome:REACT_101043 "Elongation Of The Telomeric Chromosome End, Saccharomyces cerevisiae" - xref: Reactome:REACT_91666 "Disassociation of Telomerase RNP and the Chromosome End, Sus scrofa" + xref: Reactome:REACT_113614 "Recruitment of Telomerase RNP to the Telomeric Chromosome End, Xenopus tropicalis" + xref: Reactome:REACT_92196 "Alignment Of The RNA Template On The Telomeric Chromosome End, Saccharomyces cerevisiae" + xref: Reactome:REACT_30494 "Elongation Of The Telomeric Chromosome End, Sus scrofa" + xref: Reactome:REACT_93253 "Disassociation of Telomerase RNP and the Chromosome End, Saccharomyces cerevisiae" + xref: Reactome:REACT_31549 "Elongation Of The Telomeric Chromosome End, Saccharomyces cerevisiae" + xref: Reactome:REACT_112178 "Telomere Extension By Telomerase, Xenopus tropicalis" + xref: Reactome:REACT_99699 "Recruitment of Telomerase RNP to the Telomeric Chromosome End, Saccharomyces cerevisiae" + xref: Reactome:REACT_114466 "Elongation of Extended Telomeric Chromosome End, Xenopus tropicalis" + xref: Reactome:REACT_115312 "Disassociation of Telomerase RNP and the Chromosome End, Xenopus tropicalis" + xref: Reactome:REACT_92694 "Recruitment of Telomerase RNP to the Telomeric Chromosome End, Sus scrofa" + xref: Reactome:REACT_91078 "Disassociation of Telomerase RNP and the Chromosome End, Sus scrofa" + xref: Reactome:REACT_103846 "Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End, Saccharomyces cerevisiae" + xref: Reactome:REACT_104705 "Elongation of Extended Telomeric Chromosome End, Saccharomyces cerevisiae" + xref: Reactome:REACT_114887 "Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End, Xenopus tropicalis" + xref: Reactome:REACT_113385 "Elongation Of The Telomeric Chromosome End, Xenopus tropicalis" + xref: Reactome:REACT_112155 "Alignment Of The RNA Template On The Telomeric Chromosome End, Xenopus tropicalis" + xref: Reactome:REACT_90274 "Alignment Of The RNA Template On The Telomeric Chromosome End, Sus scrofa" GO:0007018 : microtubule-based movement - xref: Reactome:REACT_88648 "Axonal transport of NGF:Trk complexes, Rattus norvegicus" + xref: Reactome:REACT_113466 "Axonal transport of NGF:Trk complexes, Caenorhabditis elegans" GO:0007023 : post-chaperonin tubulin folding pathway - xref: Reactome:REACT_98225 "Post-chaperonin tubulin folding pathway, Saccharomyces cerevisiae" - xref: Reactome:REACT_87963 "Post-chaperonin tubulin folding pathway, Schizosaccharomyces pombe" + xref: Reactome:REACT_115188 "Post-chaperonin tubulin folding pathway, Arabidopsis thaliana" + xref: Reactome:REACT_115383 "Post-chaperonin tubulin folding pathway, Oryza sativa" + xref: Reactome:REACT_113555 "Post-chaperonin tubulin folding pathway, Plasmodium falciparum" + xref: Reactome:REACT_112813 "Post-chaperonin tubulin folding pathway, Dictyostelium discoideum" + xref: Reactome:REACT_114764 "Post-chaperonin tubulin folding pathway, Caenorhabditis elegans" GO:0007062 : sister chromatid cohesion + xref: Reactome:REACT_115472 "Phosphorylation of the SA2 Cohesion Complex, Schizosaccharomyces pombe" GO:0007091 : mitotic metaphase/anaphase transition + xref: Reactome:REACT_113057 "Mitotic Metaphase/Anaphase Transition, Schizosaccharomyces pombe" GO:0007092 : activation of mitotic anaphase-promoting complex activity - xref: Reactome:REACT_105360 "Activation of the Anaphase Promoting Complex (APC) by Plk1, Saccharomyces cerevisiae" - xref: Reactome:REACT_79440 "Activation of the Anaphase Promoting Complex (APC) by Plk1, Dictyostelium discoideum" + xref: Reactome:REACT_86211 "Activation of the Anaphase Promoting Complex (APC) by Plk1, Saccharomyces cerevisiae" + xref: Reactome:REACT_97458 "Activation of the Anaphase Promoting Complex (APC) by Plk1, Dictyostelium discoideum" GO:0007094 : mitotic cell cycle spindle assembly checkpoint - xref: Reactome:REACT_108546 "Mitotic Spindle Checkpoint, Caenorhabditis elegans" GO:0007165 : signal transduction + xref: Reactome:REACT_113151 "EGFR interacts with phospholipase C-gamma, Mycobacterium tuberculosis" + xref: Reactome:REACT_114820 "EGFR interacts with phospholipase C-gamma, Sus scrofa" + xref: Reactome:REACT_114657 "EGFR interacts with phospholipase C-gamma, Dictyostelium discoideum" + xref: Reactome:REACT_114910 "EGFR interacts with phospholipase C-gamma, Caenorhabditis elegans" + xref: Reactome:REACT_112130 "EGFR interacts with phospholipase C-gamma, Oryza sativa" + xref: Reactome:REACT_114690 "EGFR interacts with phospholipase C-gamma, Saccharomyces cerevisiae" + xref: Reactome:REACT_115147 "EGFR interacts with phospholipase C-gamma, Schizosaccharomyces pombe" + xref: Reactome:REACT_113964 "EGFR interacts with phospholipase C-gamma, Bos taurus" + xref: Reactome:REACT_113601 "EGFR interacts with phospholipase C-gamma, Drosophila melanogaster" + xref: Reactome:REACT_112549 "EGFR interacts with phospholipase C-gamma, Arabidopsis thaliana" + xref: Reactome:REACT_115037 "EGFR interacts with phospholipase C-gamma, Plasmodium falciparum" GO:0007173 : epidermal growth factor receptor signaling pathway + xref: Reactome:REACT_114965 "Signaling by EGFR, Plasmodium falciparum" + xref: Reactome:REACT_115105 "Signaling by EGFR, Oryza sativa" + xref: Reactome:REACT_114791 "Signaling by EGFR, Dictyostelium discoideum" + xref: Reactome:REACT_114174 "Signaling by EGFR, Mycobacterium tuberculosis" + xref: Reactome:REACT_112423 "Signaling by EGFR, Arabidopsis thaliana" GO:0007179 : transforming growth factor beta receptor signaling pathway + xref: Reactome:REACT_114882 "Signaling by TGF beta, Caenorhabditis elegans" GO:0007189 : activation of adenylate cyclase activity by G-protein signaling pathway - xref: Reactome:REACT_80869 "Adenylate cyclase activating pathway, Dictyostelium discoideum" GO:0007190 : activation of adenylate cyclase activity - xref: Reactome:REACT_98661 "Galpha-olf:GTP binds to adenylate cyclase and activates it, Dictyostelium discoideum" GO:0007193 : inhibition of adenylate cyclase activity by G-protein signaling pathway - xref: Reactome:REACT_104417 "Adenylate cyclase inhibitory pathway, Caenorhabditis elegans" - xref: Reactome:REACT_103667 "Adenylate cyclase inhibitory pathway, Dictyostelium discoideum" GO:0007202 : activation of phospholipase C activity - xref: Reactome:REACT_34163 "PLC-gamma1 signalling, Sus scrofa" + xref: Reactome:REACT_115230 "PLC-gamma1 signalling, Arabidopsis thaliana" + xref: Reactome:REACT_114701 "PLC-gamma1 signalling, Oryza sativa" + xref: Reactome:REACT_114294 "PLC-gamma1 signalling, Plasmodium falciparum" + xref: Reactome:REACT_98083 "PLC-gamma1 signalling, Sus scrofa" GO:0007219 : Notch signaling pathway - xref: Reactome:REACT_107428 "Signaling by Notch, Sus scrofa" + xref: Reactome:REACT_76949 "Signaling by Notch, Sus scrofa" GO:0007243 : intracellular protein kinase cascade - xref: Reactome:REACT_85634 "PKA-mediated phosphorylation of key metabolic factors, Caenorhabditis elegans" - xref: Reactome:REACT_107888 "PKA-mediated phosphorylation of key metabolic factors, Drosophila melanogaster" GO:0007254 : JNK cascade - xref: Reactome:REACT_32253 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1, Saccharomyces cerevisiae" - xref: Reactome:REACT_79751 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1, Schizosaccharomyces pombe" + xref: Reactome:REACT_114745 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1, Dictyostelium discoideum" + xref: Reactome:REACT_114741 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1, Oryza sativa" + xref: Reactome:REACT_112172 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1, Arabidopsis thaliana" GO:0007264 : small GTPase mediated signal transduction + xref: Reactome:REACT_115149 "Signalling to p38 via RIT and RIN, Dictyostelium discoideum" + xref: Reactome:REACT_114399 "Signalling to p38 via RIT and RIN, Arabidopsis thaliana" + xref: Reactome:REACT_113091 "Signalling to p38 via RIT and RIN, Oryza sativa" GO:0007265 : Ras protein signal transduction + xref: Reactome:REACT_114204 "Signalling to RAS, Oryza sativa" + xref: Reactome:REACT_114859 "Signalling to RAS, Arabidopsis thaliana" + xref: Reactome:REACT_115010 "Signalling to RAS, Dictyostelium discoideum" GO:0007268 : synaptic transmission - xref: Reactome:REACT_89065 "Synaptic Transmission, Gallus gallus" - xref: Reactome:REACT_88891 "Synaptic Transmission, Mycobacterium tuberculosis" - xref: Reactome:REACT_86628 "Synaptic Transmission, Canis familiaris" - xref: Reactome:REACT_86563 "Synaptic Transmission, Mus musculus" - xref: Reactome:REACT_99952 "Synaptic Transmission, Oryza sativa" - xref: Reactome:REACT_13685 "Synaptic Transmission, Homo sapiens" - xref: Reactome:REACT_104894 "Synaptic Transmission, Xenopus tropicalis" - xref: Reactome:REACT_78038 "Synaptic Transmission, Rattus norvegicus" - xref: Reactome:REACT_80052 "Synaptic Transmission, Schizosaccharomyces pombe" - xref: Reactome:REACT_88599 "Synaptic Transmission, Bos taurus" - xref: Reactome:REACT_29595 "Synaptic Transmission, Caenorhabditis elegans" - xref: Reactome:REACT_33434 "Synaptic Transmission, Escherichia coli" - xref: Reactome:REACT_102748 "Synaptic Transmission, Saccharomyces cerevisiae" - xref: Reactome:REACT_29254 "Synaptic Transmission, Danio rerio" - xref: Reactome:REACT_33322 "Synaptic Transmission, Taeniopygia guttata" - xref: Reactome:REACT_77013 "Transmission across Chemical Synapses, Sus scrofa" - xref: Reactome:REACT_78409 "Synaptic Transmission, Sus scrofa" - xref: Reactome:REACT_89149 "Synaptic Transmission, Dictyostelium discoideum" - xref: Reactome:REACT_82746 "Synaptic Transmission, Arabidopsis thaliana" - xref: Reactome:REACT_89785 "Synaptic Transmission, Drosophila melanogaster" + xref: Reactome:REACT_113444 "Neuronal System, Staphylococcus aureus N315" + xref: Reactome:REACT_88599 "Neuronal System, Bos taurus" + xref: Reactome:REACT_86628 "Neuronal System, Canis familiaris" + xref: Reactome:REACT_102748 "Neuronal System, Saccharomyces cerevisiae" + xref: Reactome:REACT_30266 "Transmission across Chemical Synapses, Sus scrofa" + xref: Reactome:REACT_104894 "Neuronal System, Xenopus tropicalis" + xref: Reactome:REACT_13685 "Neuronal System, Homo sapiens" + xref: Reactome:REACT_33434 "Neuronal System, Escherichia coli" + xref: Reactome:REACT_89785 "Neuronal System, Drosophila melanogaster" + xref: Reactome:REACT_107151 "Neuronal System, Sus scrofa" + xref: Reactome:REACT_88891 "Neuronal System, Mycobacterium tuberculosis" + xref: Reactome:REACT_29595 "Neuronal System, Caenorhabditis elegans" + xref: Reactome:REACT_78038 "Neuronal System, Rattus norvegicus" + xref: Reactome:REACT_86563 "Neuronal System, Mus musculus" + xref: Reactome:REACT_89065 "Neuronal System, Gallus gallus" + xref: Reactome:REACT_112265 "Transmission across Chemical Synapses, Staphylococcus aureus N315" + xref: Reactome:REACT_33322 "Neuronal System, Taeniopygia guttata" + xref: Reactome:REACT_89149 "Neuronal System, Dictyostelium discoideum" + xref: Reactome:REACT_80052 "Neuronal System, Schizosaccharomyces pombe" + xref: Reactome:REACT_82746 "Neuronal System, Arabidopsis thaliana" + xref: Reactome:REACT_29254 "Neuronal System, Danio rerio" + xref: Reactome:REACT_99952 "Neuronal System, Oryza sativa" GO:0007269 : neurotransmitter secretion - xref: Reactome:REACT_95869 "Neurotransmitter Release Cycle, Sus scrofa" + xref: Reactome:REACT_113329 "Neurotransmitter Release Cycle, Staphylococcus aureus N315" + xref: Reactome:REACT_110862 "Neurotransmitter Release Cycle, Sus scrofa" + xref: Reactome:REACT_115061 "Neurotransmitter Release Cycle, Dictyostelium discoideum" GO:0007411 : axon guidance - xref: Reactome:REACT_109333 "Axon guidance, Schizosaccharomyces pombe" + xref: Reactome:REACT_108197 "Axon guidance, Schizosaccharomyces pombe" + xref: Reactome:REACT_112315 "Axon guidance, Plasmodium falciparum" + xref: Reactome:REACT_115127 "Axon guidance, Oryza sativa" + xref: Reactome:REACT_114665 "Axon guidance, Arabidopsis thaliana" GO:0007588 : excretion - is_a: GO:0046903 GO:0007596 : blood coagulation - xref: Reactome:REACT_108655 "Hemostasis, Escherichia coli" + xref: Reactome:REACT_113650 "Common Pathway, Drosophila melanogaster" + xref: Reactome:REACT_114152 "Formation of Fibrin Clot (Clotting Cascade), Drosophila melanogaster" GO:0008028 : monocarboxylic acid transmembrane transporter activity - xref: Reactome:REACT_34564 "Na+-dependent monocarboxylate transport by SMCT, Xenopus tropicalis" - xref: Reactome:REACT_29913 "Na+-dependent monocarboxylate transport by SMCT, Gallus gallus" - xref: Reactome:REACT_106228 "Na+-dependent monocarboxylate transport by SMCT, Rattus norvegicus" - xref: Reactome:REACT_82190 "Na+-dependent monocarboxylate transport by SMCT, Canis familiaris" - xref: Reactome:REACT_93426 "Na+-dependent monocarboxylate transport by SMCT, Taeniopygia guttata" - xref: Reactome:REACT_87687 "Na+-dependent monocarboxylate transport by SMCT, Bos taurus" - xref: Reactome:REACT_31459 "Na+-dependent monocarboxylate transport by SMCT, Staphylococcus aureus N315" - xref: Reactome:REACT_29629 "Na+-dependent monocarboxylate transport by SMCT, Sus scrofa" - xref: Reactome:REACT_109633 "Na+-dependent monocarboxylate transport by SMCT, Mus musculus" - xref: Reactome:REACT_85102 "Na+-dependent monocarboxylate transport by SMCT, Danio rerio" + xref: Reactome:REACT_115467 "MCTs mediate proton-coupled transport of monocarboxylates and ketone bodies, Saccharomyces cerevisiae" + xref: Reactome:REACT_114096 "MCTs mediate proton-coupled transport of monocarboxylates and ketone bodies, Drosophila melanogaster" GO:0008029 : pentraxin receptor activity - is_a: GO:0001864 + relationship: has_part GO:0001864 GO:0008061 : chitin binding - def: Interacting selectively and non-covalently with chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues. + def: Interacting selectively and non-covalently with chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. GO:0008063 : Toll signaling pathway - xref: Reactome:REACT_79117 "Toll Like Receptor 4 (TLR4) Cascade, Caenorhabditis elegans" + xref: Reactome:REACT_109528 "Toll Like Receptor 4 (TLR4) Cascade, Caenorhabditis elegans" GO:0008066 : glutamate receptor activity + relationship: has_part GO:0016595 GO:0008116 : prostaglandin-I synthase activity + xref: Reactome:REACT_114097 "Prostacyclin synthase (CYP8A1) mediates the isomerization of prostaglandin H2 to prostaglandin I2, Dictyostelium discoideum" + xref: Reactome:REACT_113532 "Prostacyclin synthase (CYP8A1) mediates the isomerization of prostaglandin H2 to prostaglandin I2, Arabidopsis thaliana" + xref: Reactome:REACT_114523 "Prostacyclin synthase (CYP8A1) mediates the isomerization of prostaglandin H2 to prostaglandin I2, Oryza sativa" + xref: Reactome:REACT_112323 "Prostacyclin synthase (CYP8A1) mediates the isomerization of prostaglandin H2 to prostaglandin I2, Mycobacterium tuberculosis" GO:0008117 : sphinganine-1-phosphate aldolase activity + xref: Reactome:REACT_113335 "sphingosine 1-phosphate => phosphoethanolamine + hexadec-2-enal, Caenorhabditis elegans" + xref: Reactome:REACT_113234 "sphinganine 1-phosphate => phosphoethanolamine + hexadecanal, Caenorhabditis elegans" + xref: Reactome:REACT_113298 "sphinganine 1-phosphate => phosphoethanolamine + hexadecanal, Escherichia coli" + xref: Reactome:REACT_114175 "sphingosine 1-phosphate => phosphoethanolamine + hexadec-2-enal, Escherichia coli" GO:0008119 : thiopurine S-methyltransferase activity - xref: Reactome:REACT_96049 "6-mercaptopurine can be S-methylated, Sus scrofa" + xref: Reactome:REACT_30624 "6-mercaptopurine can be S-methylated, Sus scrofa" GO:0008123 : cholesterol 7-alpha-monooxygenase activity + xref: Reactome:REACT_112443 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Mycobacterium tuberculosis" + xref: Reactome:REACT_114538 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Oryza sativa" + xref: Reactome:REACT_114617 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Dictyostelium discoideum" + xref: Reactome:REACT_113215 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Arabidopsis thaliana" GO:0008124 : 4-alpha-hydroxytetrahydrobiopterin dehydratase activity + xref: Reactome:REACT_113243 "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O, Caenorhabditis elegans" GO:0008131 : primary amine oxidase activity - xref: Reactome:REACT_30414 "Oxidation of 3-Methoxytyramine to homovanillic acid, Bos taurus" - xref: Reactome:REACT_78571 "oxidation of dopamine to 3,4dihydroxyphenylacetic acid (DOPAC), Bos taurus" - xref: Reactome:REACT_77866 "Dietary tyramine is oxidatively deaminated to an aldehyde by MAOB, Gallus gallus" + xref: Reactome:REACT_115498 "Metabolism of Noradrenaline, Dictyostelium discoideum" + xref: Reactome:REACT_114320 "Oxidation of 3-Methoxytyramine to homovanillic acid, Dictyostelium discoideum" + xref: Reactome:REACT_113622 "Dietary tyramine is oxidatively deaminated to an aldehyde by MAOB, Dictyostelium discoideum" + xref: Reactome:REACT_112188 "oxidation of dopamine to 3,4dihydroxyphenylacetic acid (DOPAC), Dictyostelium discoideum" + xref: Reactome:REACT_100172 "oxidation of dopamine to 3,4dihydroxyphenylacetic acid (DOPAC), Bos taurus" + xref: Reactome:REACT_112919 "Oxidative deamination of Phenyethylamine by MAOB, Dictyostelium discoideum" + xref: Reactome:REACT_112132 "Oxidative deamination of 5-Hydroxytryptamine by MAOA, Dictyostelium discoideum" + xref: Reactome:REACT_104381 "Oxidation of 3-Methoxytyramine to homovanillic acid, Bos taurus" GO:0008146 : sulfotransferase activity - xref: Reactome:REACT_87853 "taurolithocholate + PAPS => taurolithocholate sulfate + PAP, Danio rerio" - xref: Reactome:REACT_92241 "N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP, Taeniopygia guttata" - xref: Reactome:REACT_93270 "N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP, Gallus gallus" - xref: Reactome:REACT_92715 "lithocholate + PAPS => lithocholate sulfate + PAP, Danio rerio" + xref: Reactome:REACT_113711 "N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP, Danio rerio" GO:0008158 : hedgehog receptor activity - def: Combining with the hedgehog protein to initiate a change in cell activity. + def: Combining with a hedgehog protein to initiate a change in cell activity. + relationship: has_part GO:0097108 GO:0008168 : methyltransferase activity - xref: Reactome:REACT_80832 "methylation of Dopamine to form 3-Methoxytyramine, Bos taurus" - xref: Reactome:REACT_80424 "Methylation of 3,4-dihydroxypheylacetic acid to homovanillic acid, Bos taurus" + xref: Reactome:REACT_29020 "methylation of Dopamine to form 3-Methoxytyramine, Bos taurus" + xref: Reactome:REACT_100745 "Methylation of 3,4-dihydroxypheylacetic acid to homovanillic acid, Bos taurus" GO:0008173 : RNA methyltransferase activity - xref: Reactome:REACT_88299 "snRNA Cap hypermethylation, Sus scrofa" GO:0008177 : succinate dehydrogenase (ubiquinone) activity - xref: Reactome:REACT_91586 "Transfer of electrons through the succinate dehydrogenase complex, Saccharomyces cerevisiae" + xref: Reactome:REACT_88562 "Transfer of electrons through the succinate dehydrogenase complex, Saccharomyces cerevisiae" GO:0008179 : adenylate cyclase binding - xref: Reactome:REACT_98661 "Galpha-olf:GTP binds to adenylate cyclase and activates it, Dictyostelium discoideum" GO:0008184 : glycogen phosphorylase activity - xref: Reactome:REACT_84225 "glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL], Saccharomyces cerevisiae" + xref: Reactome:REACT_114725 "poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB], Xenopus tropicalis" + xref: Reactome:REACT_114709 "glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB], Xenopus tropicalis" + xref: Reactome:REACT_112994 "poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL], Caenorhabditis elegans" + xref: Reactome:REACT_113339 "poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB], Arabidopsis thaliana" + xref: Reactome:REACT_114127 "glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB], Caenorhabditis elegans" + xref: Reactome:REACT_113915 "glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL], Caenorhabditis elegans" + xref: Reactome:REACT_112518 "glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL], Arabidopsis thaliana" + xref: Reactome:REACT_107584 "glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL], Saccharomyces cerevisiae" + xref: Reactome:REACT_115476 "glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL], Danio rerio" + xref: Reactome:REACT_112008 "poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB], Caenorhabditis elegans" + xref: Reactome:REACT_112419 "poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL], Danio rerio" + xref: Reactome:REACT_113449 "poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL], Arabidopsis thaliana" + xref: Reactome:REACT_112595 "glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB], Arabidopsis thaliana" GO:0008188 : neuropeptide receptor activity - is_a: GO:0042923 + relationship: has_part GO:0042923 GO:0008194 : UDP-glycosyltransferase activity - xref: Reactome:REACT_89213 "phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP, Sus scrofa" + xref: Reactome:REACT_92152 "phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP, Sus scrofa" GO:0008195 : phosphatidate phosphatase activity - xref: Reactome:REACT_102146 "Dephosphorylation of AKT by PP2A, Dictyostelium discoideum" + xref: Reactome:REACT_112281 "1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate, Drosophila melanogaster" GO:0008201 : heparin binding - def: Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha1-4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. + def: Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. GO:0008202 : steroid metabolic process - xref: Reactome:REACT_31074 "Metabolism of steroid hormones and vitamins A and D, Plasmodium falciparum" + xref: Reactome:REACT_97355 "Metabolism of steroid hormones and vitamins A and D, Plasmodium falciparum" GO:0008206 : bile acid metabolic process - xref: Reactome:REACT_28750 "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine, Sus scrofa" + xref: Reactome:REACT_99705 "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine, Sus scrofa" + xref: Reactome:REACT_113960 "Bile acid and bile salt metabolism, Plasmodium falciparum" + xref: Reactome:REACT_115499 "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine, Gallus gallus" GO:0008215 : spermine metabolic process - xref: Reactome:REACT_78052 "Spermine is oxidized to spermidine, Saccharomyces cerevisiae" + xref: Reactome:REACT_114114 "Spermine is oxidized to spermidine, Caenorhabditis elegans" + xref: Reactome:REACT_114150 "Spermine is oxidized to spermidine, Drosophila melanogaster" + xref: Reactome:REACT_84703 "Spermine is oxidized to spermidine, Saccharomyces cerevisiae" GO:0008237 : metallopeptidase activity - xref: Reactome:REACT_104946 "Notch 2-ligand complex is cleaved to produce NEXT2, Taeniopygia guttata" - xref: Reactome:REACT_106676 "Notch 2-ligand complex is cleaved to produce NEXT2, Sus scrofa" - xref: Reactome:REACT_90446 "Notch 4-ligand complex is cleaved to produce NEXT4, Sus scrofa" + xref: Reactome:REACT_83310 "Notch 2-ligand complex is cleaved to produce NEXT2, Sus scrofa" + xref: Reactome:REACT_114094 "Notch 3-ligand complex is cleaved to produce NEXT3, Drosophila melanogaster" + xref: Reactome:REACT_100129 "Notch 4-ligand complex is cleaved to produce NEXT4, Sus scrofa" + xref: Reactome:REACT_115138 "Notch 4-ligand complex is cleaved to produce NEXT4, Xenopus tropicalis" GO:0008253 : 5'-nucleotidase activity - xref: Reactome:REACT_77651 "CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E], Drosophila melanogaster" - xref: Reactome:REACT_81698 "AMP, dAMP, GMP, or IMP + H2O => adenosine, deoxyadenosine, guanosine, or inosine + orthophosphate [NT5E], Drosophila melanogaster" GO:0008260 : 3-oxoacid CoA-transferase activity - xref: Reactome:REACT_90587 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Escherichia coli" - xref: Reactome:REACT_28387 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Gallus gallus" - xref: Reactome:REACT_81222 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Drosophila melanogaster" - xref: Reactome:REACT_33458 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Caenorhabditis elegans" - xref: Reactome:REACT_82464 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Mycobacterium tuberculosis" - xref: Reactome:REACT_86080 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Mus musculus" - xref: Reactome:REACT_95458 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Sus scrofa" - xref: Reactome:REACT_31223 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Danio rerio" - xref: Reactome:REACT_90429 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Taeniopygia guttata" - xref: Reactome:REACT_110993 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Bos taurus" - xref: Reactome:REACT_88464 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Dictyostelium discoideum" - xref: Reactome:REACT_101965 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Rattus norvegicus" - xref: Reactome:REACT_1796 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Homo sapiens" - xref: Reactome:REACT_89608 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Canis familiaris" + xref: Reactome:REACT_1796 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Homo sapiens" + xref: Reactome:REACT_82464 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Mycobacterium tuberculosis" + xref: Reactome:REACT_28387 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Gallus gallus" + xref: Reactome:REACT_86080 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Mus musculus" + xref: Reactome:REACT_89608 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Canis familiaris" + xref: Reactome:REACT_90429 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Taeniopygia guttata" + xref: Reactome:REACT_101965 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Rattus norvegicus" + xref: Reactome:REACT_95458 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Sus scrofa" + xref: Reactome:REACT_81222 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Drosophila melanogaster" + xref: Reactome:REACT_31223 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Danio rerio" + xref: Reactome:REACT_110993 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Bos taurus" + xref: Reactome:REACT_33458 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Caenorhabditis elegans" + xref: Reactome:REACT_112252 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Xenopus tropicalis" + xref: Reactome:REACT_88464 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Dictyostelium discoideum" GO:0008262 : importin-alpha export receptor activity - is_a: GO:0008565 GO:0008286 : insulin receptor signaling pathway - xref: Reactome:REACT_108250 "Signaling by Insulin receptor, Dictyostelium discoideum" + xref: Reactome:REACT_103763 "Signaling by Insulin receptor, Dictyostelium discoideum" GO:0008294 : calcium- and calmodulin-responsive adenylate cyclase activity - xref: Reactome:REACT_104598 "Adenylate cyclase produces cAMP, Dictyostelium discoideum" GO:0008321 : Ral guanyl-nucleotide exchange factor activity - xref: Reactome:REACT_87405 "Guanine nucleotide exchange on Ral, Caenorhabditis elegans" + xref: Reactome:REACT_111942 "Guanine nucleotide exchange on Ral, Xenopus tropicalis" + xref: Reactome:REACT_115506 "Guanine nucleotide exchange on Ral, Taeniopygia guttata" GO:0008329 : pattern recognition receptor activity + relationship: has_part GO:0001871 GO:0008334 : histone mRNA metabolic process - xref: Reactome:REACT_105929 "Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA, Sus scrofa" - xref: Reactome:REACT_90689 "SLBP independent Processing of Histone Pre-mRNAs, Sus scrofa" - xref: Reactome:REACT_103016 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs, Sus scrofa" - xref: Reactome:REACT_81694 "Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA, Sus scrofa" + xref: Reactome:REACT_114133 "Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA, Caenorhabditis elegans" + xref: Reactome:REACT_112727 "SLBP independent Processing of Histone Pre-mRNAs, Danio rerio" + xref: Reactome:REACT_84828 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs, Sus scrofa" + xref: Reactome:REACT_113499 "Binding of SLBP to Replication-Dependent Histone Pre-mRNA, Dictyostelium discoideum" + xref: Reactome:REACT_113687 "Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA, Caenorhabditis elegans" + xref: Reactome:REACT_115024 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs, Danio rerio" + xref: Reactome:REACT_115517 "SLBP independent Processing of Histone Pre-mRNAs, Caenorhabditis elegans" + xref: Reactome:REACT_112829 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs, Caenorhabditis elegans" + xref: Reactome:REACT_115064 "Binding of SLBP to Replication-Dependent Histone Pre-mRNA, Drosophila melanogaster" + xref: Reactome:REACT_114009 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs, Drosophila melanogaster" + xref: Reactome:REACT_112752 "Binding of SLBP to Replication-Dependent Histone Pre-mRNA, Caenorhabditis elegans" + xref: Reactome:REACT_114241 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs, Dictyostelium discoideum" + xref: Reactome:REACT_115510 "Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA, Danio rerio" + xref: Reactome:REACT_113849 "Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA, Drosophila melanogaster" + xref: Reactome:REACT_113897 "Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA, Drosophila melanogaster" + xref: Reactome:REACT_113324 "Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA, Danio rerio" + xref: Reactome:REACT_115116 "Binding of SLBP to Replication-Dependent Histone Pre-mRNA, Danio rerio" + xref: Reactome:REACT_114040 "SLBP independent Processing of Histone Pre-mRNAs, Drosophila melanogaster" GO:0008336 : gamma-butyrobetaine dioxygenase activity + xref: Reactome:REACT_114022 "gamma-butyrobetaine + alpha-ketoglutarate + O2 => carnitine + succinate + CO2, Saccharomyces cerevisiae" GO:0008374 : O-acyltransferase activity - xref: Reactome:REACT_28943 "glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH, Saccharomyces cerevisiae" - xref: Reactome:REACT_84008 "glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH, Sus scrofa" + xref: Reactome:REACT_78639 "glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH, Saccharomyces cerevisiae" + xref: Reactome:REACT_90799 "glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH, Sus scrofa" GO:0008380 : RNA splicing + xref: Reactome:REACT_113880 "mRNA Splicing, Taeniopygia guttata" GO:0008386 : cholesterol monooxygenase (side-chain-cleaving) activity - xref: Reactome:REACT_34495 "20alpha,22beta-hydroxycholesterol is cleaved by CYP11A1 to yield pregnenolone and isocaproaldehyde, Caenorhabditis elegans" - xref: Reactome:REACT_28582 "Oxidation of cholesterol to 22beta-hydroxycholesterol, Caenorhabditis elegans" - xref: Reactome:REACT_79782 "Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol, Caenorhabditis elegans" GO:0008389 : coumarin 7-hydroxylase activity - xref: Reactome:REACT_88845 "Coumarin is 7-hydroxylated by CYP2A13, Canis familiaris" - xref: Reactome:REACT_108785 "Coumarin is 7-hydroxylated by CYP2A13, Sus scrofa" + xref: Reactome:REACT_112622 "Coumarin is 7-hydroxylated by CYP2A6, Xenopus tropicalis" + xref: Reactome:REACT_113359 "Coumarin is 7-hydroxylated by CYP2A6, Mus musculus" + xref: Reactome:REACT_113450 "Coumarin is 7-hydroxylated by CYP2A6, Rattus norvegicus" + xref: Reactome:REACT_112822 "Coumarin is 7-hydroxylated by CYP2A6, Danio rerio" GO:0008395 : steroid hydroxylase activity - xref: Reactome:REACT_78684 "Conversion of 18-hydroxycorticosterone to aldosterone, Caenorhabditis elegans" - xref: Reactome:REACT_89675 "5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol, Sus scrofa" - xref: Reactome:REACT_102026 "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA), Caenorhabditis elegans" - xref: Reactome:REACT_94011 "3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA), Caenorhabditis elegans" - xref: Reactome:REACT_108747 "5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al, Caenorhabditis elegans" - xref: Reactome:REACT_83402 "5beta-cholestan-3alpha, 7alpha, 12alpha-triol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 12alpha, 27-tetrol, Caenorhabditis elegans" - xref: Reactome:REACT_104501 "Cholesterol is hydroxylated to 27-hydroxycholesterol by CYP27, Caenorhabditis elegans" - xref: Reactome:REACT_86874 "3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA), Caenorhabditis elegans" - xref: Reactome:REACT_90245 "5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol, Caenorhabditis elegans" - xref: Reactome:REACT_80351 "5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al, Caenorhabditis elegans" - xref: Reactome:REACT_92991 "5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol, Caenorhabditis elegans" - xref: Reactome:REACT_108033 "Hydroxylation of corticosterone to form 18-hydroxycorticosterone, Caenorhabditis elegans" - xref: Reactome:REACT_88364 "5beta-cholestan-3alpha,7alpha,24(S)-triol is hydroxylated to 5beta-cholestan-3alpha,7alpha,24(S), 27-tetrol, Caenorhabditis elegans" - xref: Reactome:REACT_34510 "5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al, Caenorhabditis elegans" - xref: Reactome:REACT_102407 "5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al, Caenorhabditis elegans" - xref: Reactome:REACT_103979 "3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA), Caenorhabditis elegans" + xref: Reactome:REACT_112201 "Cholesterol is hydroxylated to 25-hydroxycholesterol, Xenopus tropicalis" + xref: Reactome:REACT_28778 "5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol, Sus scrofa" GO:0008396 : oxysterol 7-alpha-hydroxylase activity + xref: Reactome:REACT_112857 "27-hydroxycholesterol is 7alpha-hydroxylated, Dictyostelium discoideum" + xref: Reactome:REACT_115480 "24-hydroxycholesterol is 7alpha-hydroxylated to yield cholest-5-ene-3beta,7alpha,24-triol, Oryza sativa" + xref: Reactome:REACT_113710 "27-hydroxycholesterol is 7alpha-hydroxylated, Mycobacterium tuberculosis" + xref: Reactome:REACT_112291 "25-hydroxycholesterol is 7alpha-hydroxylated by CYP7B1, Oryza sativa" + xref: Reactome:REACT_112636 "27-hydroxycholesterol is 7alpha-hydroxylated, Arabidopsis thaliana" + xref: Reactome:REACT_114585 "24-hydroxycholesterol is 7alpha-hydroxylated to yield cholest-5-ene-3beta,7alpha,24-triol, Arabidopsis thaliana" + xref: Reactome:REACT_113559 "27-hydroxycholesterol is 7alpha-hydroxylated, Oryza sativa" + xref: Reactome:REACT_114849 "25-hydroxycholesterol is 7alpha-hydroxylated by CYP7B1, Mycobacterium tuberculosis" + xref: Reactome:REACT_114797 "25-hydroxycholesterol is 7alpha-hydroxylated by CYP7B1, Arabidopsis thaliana" + xref: Reactome:REACT_112158 "24-hydroxycholesterol is 7alpha-hydroxylated to yield cholest-5-ene-3beta,7alpha,24-triol, Dictyostelium discoideum" + xref: Reactome:REACT_114515 "25-hydroxycholesterol is 7alpha-hydroxylated by CYP7B1, Dictyostelium discoideum" + xref: Reactome:REACT_115504 "24-hydroxycholesterol is 7alpha-hydroxylated to yield cholest-5-ene-3beta,7alpha,24-triol, Mycobacterium tuberculosis" GO:0008398 : sterol 14-demethylase activity - xref: Reactome:REACT_98968 "Lanosterol is oxidatively demethylated to 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol, Rattus norvegicus" - xref: Reactome:REACT_88673 "Lanosterol is oxidatively demethylated to 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol, Sus scrofa" + xref: Reactome:REACT_29216 "Lanosterol is oxidatively demethylated to 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol, Sus scrofa" GO:0008407 : chaeta morphogenesis - name: bristle morphogenesis + name: chaeta morphogenesis - def: The process in which the anatomical structures of the bristle are generated and organized. + def: The process in which the anatomical structures of the chaeta are generated and organized. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell. + synonym: "bristle morphogenesis" NARROW [GOC:bf, GOC:dos] GO:0008424 : glycoprotein 6-alpha-L-fucosyltransferase activity + synonym: "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1,6)fucosyltransferase activity" EXACT [EC:2.4.1.68] + synonym: "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1,6)fucosyltransferase activity" EXACT [EC:2.4.1.68] GO:0008442 : 3-hydroxyisobutyrate dehydrogenase activity - xref: Reactome:REACT_87005 "beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+, Caenorhabditis elegans" + xref: Reactome:REACT_95495 "beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+, Caenorhabditis elegans" GO:0008455 : alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity - synonym: "UDP-GlcNAc:mannoside alpha1-6 acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] - synonym: "uridine diphosphoacetylglucosamine-alpha-D-mannoside beta-1-2-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] - synonym: "uridine diphosphoacetylglucosamine-alpha-1,6-mannosylglycoprotein beta-1-2-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] - synonym: "uridine diphosphoacetylglucosamine-alpha-D-mannoside beta1-2-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] - synonym: "UDP-GlcNAc:mannoside alpha-1-6 acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] - synonym: "uridine diphosphoacetylglucosamine-mannoside alpha-1->6-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] - synonym: "uridine diphosphoacetylglucosamine-mannoside alpha1->6-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] + synonym: "uridine diphosphoacetylglucosamine-mannoside alpha(1,6)-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] + synonym: "UDP-GlcNAc:mannoside alpha-1,6 acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] + synonym: "uridine diphosphoacetylglucosamine-alpha-D-mannoside beta-1,2-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] + synonym: "UDP-GlcNAc:mannoside alpha-(1,6) acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] + synonym: "uridine diphosphoacetylglucosamine-alpha-D-mannoside beta(1,2)-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] + synonym: "uridine diphosphoacetylglucosamine-mannoside alpha-1,6-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] + synonym: "uridine diphosphoacetylglucosamine-alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143] GO:0008466 : glycogenin glucosyltransferase activity + xref: Reactome:REACT_113130 "8 UDP-glucose + glycogenin dimer => 8 UDP + {(1,4)-alpha-D-glucosyl}4 glycogenin dimer, Arabidopsis thaliana" GO:0008470 : isovaleryl-CoA dehydrogenase activity - xref: Reactome:REACT_77372 "isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2, Caenorhabditis elegans" + xref: Reactome:REACT_28761 "isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2, Caenorhabditis elegans" GO:0008481 : sphinganine kinase activity + xref: Reactome:REACT_112755 "sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP, Caenorhabditis elegans" GO:0008496 : mannan endo-1,6-alpha-mannosidase activity - def: Catalysis of the random hydrolysis of 1,6-alpha-D-mannosidic linkages in unbranched 1,6-mannans. + def: Catalysis of the random hydrolysis of (1->6)-alpha-D-mannosidic linkages in unbranched (1->6)-mannans. GO:0008504 : monoamine transmembrane transporter activity - xref: Reactome:REACT_80372 "Reuptake of dopamine from the synaptic cleft into neurons, Bos taurus" - xref: Reactome:REACT_109976 "loading of Serotonin in synaptic vesicles, Xenopus tropicalis" - xref: Reactome:REACT_105284 "Reuptake of dopamine from the synaptic cleft into neurons, Drosophila melanogaster" - xref: Reactome:REACT_101967 "Reuptake of dopamine from the synaptic cleft into neurons, Caenorhabditis elegans" - xref: Reactome:REACT_91449 "Loading of dopamine into synaptic veiscles, Xenopus tropicalis" + xref: Reactome:REACT_30134 "Reuptake of dopamine from the synaptic cleft into neurons, Bos taurus" GO:0008508 : bile acid:sodium symporter activity - xref: Reactome:REACT_28793 "Co-transport (influx) of bile salts and sodium ions by NTCP, Gallus gallus" + xref: Reactome:REACT_112308 "SOAT can transport taurolithocholate-3-sulphate, Staphylococcus aureus N315" + xref: Reactome:REACT_114427 "Co-transport (influx) of bile salts and sodium ions by NTCP, Danio rerio" + xref: Reactome:REACT_114282 "Co-transport (influx) of bile salts and acids and sodium ions by ASBT, Xenopus tropicalis" + xref: Reactome:REACT_114684 "Co-transport (influx) of bile salts and sodium ions by NTCP, Xenopus tropicalis" GO:0008510 : sodium:bicarbonate symporter activity - xref: Reactome:REACT_92350 "Na+-coupled HCO3- cotransport, Sus scrofa" + xref: Reactome:REACT_113404 "Na+-coupled HCO3- cotransport, Dictyostelium discoideum" + xref: Reactome:REACT_86222 "Na+-coupled HCO3- cotransport, Sus scrofa" GO:0008517 : folic acid transporter activity - xref: Reactome:REACT_83407 "Mitochondrial tetrahydrofolate export across the inner mitochondrial membrane, Sus scrofa" - xref: Reactome:REACT_108089 "Cytosolic tetrahydrofolate import across the inner mitochondrial membrane, Dictyostelium discoideum" + xref: Reactome:REACT_98444 "Cytosolic tetrahydrofolate import across the inner mitochondrial membrane, Dictyostelium discoideum" + xref: Reactome:REACT_90989 "Mitochondrial tetrahydrofolate export across the inner mitochondrial membrane, Sus scrofa" GO:0008523 : sodium-dependent multivitamin transmembrane transporter activity - xref: Reactome:REACT_108516 "Biotin transport across the plasma membrane, Sus scrofa" + xref: Reactome:REACT_83124 "Biotin transport across the plasma membrane, Sus scrofa" GO:0008531 : riboflavin kinase activity + xref: Reactome:REACT_114647 "Riboflavin is phosphorylated to FMN, Canis familiaris" GO:0008532 : N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity - synonym: "N-acetyllactosamine beta(1-3)N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.149] - synonym: "UDP-GlcNAc:Galbeta1->4GlcNAcbeta-rbeta1->3-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.149] + synonym: "UDP-GlcNAc:Galbeta-1,4-GlcNAcbeta-beta-1,3-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.149] + synonym: "N-acetyllactosamine beta(1,3)N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.149] + synonym: "UDP-GlcNAc:Galbeta-(1,4)-GlcNAcbeta-r-beta-(1,3)-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.149] + synonym: "uridine diphosphoacetylglucosamine-acetyllactosaminide beta-1,3-acetylglucosaminyltransferase" BROAD [EC:2.4.1.149] GO:0008534 : oxidized purine base lesion DNA N-glycosylase activity - synonym: "fapy-DNA glycosylase activity" EXACT [EC:3.2.2.23] - xref: Reactome:REACT_107147 "Cleavage of formamidopyrimidine by hOGG1 glycosylase, Xenopus tropicalis" - xref: Reactome:REACT_103037 "Cleavage of formamidopyrimidine by hOGG1 glycosylase, Taeniopygia guttata" - xref: Reactome:REACT_90804 "Cleavage of formamidopyrimidine by hOGG1 glycosylase, Saccharomyces cerevisiae" - xref: Reactome:REACT_93190 "Cleavage of 8-oxo guanine by hOGG1 glycosylase, Xenopus tropicalis" - xref: Reactome:REACT_93002 "Cleavage of 8-oxo guanine by hOGG1 glycosylase, Taeniopygia guttata" - xref: Reactome:REACT_31170 "Cleavage of 8-oxo guanine by hOGG1 glycosylase, Saccharomyces cerevisiae" + xref: Reactome:REACT_28730 "Cleavage of 8-oxo guanine by hOGG1 glycosylase, Saccharomyces cerevisiae" + xref: Reactome:REACT_88552 "Cleavage of formamidopyrimidine by hOGG1 glycosylase, Saccharomyces cerevisiae" GO:0008543 : fibroblast growth factor receptor signaling pathway - xref: Reactome:REACT_83604 "Signaling by FGFR, Sus scrofa" + xref: Reactome:REACT_115170 "FGFR1 ligand binding and activation, Caenorhabditis elegans" + xref: Reactome:REACT_102813 "Signaling by FGFR, Sus scrofa" + xref: Reactome:REACT_112148 "FGFR1b ligand binding and activation, Drosophila melanogaster" + xref: Reactome:REACT_114115 "FGFR3 ligand binding and activation, Caenorhabditis elegans" + xref: Reactome:REACT_113040 "FGFR1c ligand binding and activation, Caenorhabditis elegans" + xref: Reactome:REACT_112770 "FGFR2 ligand binding and activation, Caenorhabditis elegans" + xref: Reactome:REACT_113498 "FGFR3b ligand binding and activation, Caenorhabditis elegans" + xref: Reactome:REACT_113682 "FGFR3c ligand binding and activation, Caenorhabditis elegans" + xref: Reactome:REACT_113367 "Signaling by FGFR, Plasmodium falciparum" + xref: Reactome:REACT_114328 "Signaling by FGFR, Saccharomyces cerevisiae" + xref: Reactome:REACT_115356 "FGFR ligand binding and activation, Caenorhabditis elegans" + xref: Reactome:REACT_114162 "FGFR2b ligand binding and activation, Caenorhabditis elegans" + xref: Reactome:REACT_114758 "FGFR2c ligand binding and activation, Caenorhabditis elegans" + xref: Reactome:REACT_115181 "Signaling by FGFR, Schizosaccharomyces pombe" + xref: Reactome:REACT_112458 "Signaling by FGFR, Mycobacterium tuberculosis" + xref: Reactome:REACT_115350 "FGFR4 ligand binding and activation, Caenorhabditis elegans" + xref: Reactome:REACT_114804 "FGFR2b ligand binding and activation, Drosophila melanogaster" + xref: Reactome:REACT_115307 "FGFR1b ligand binding and activation, Caenorhabditis elegans" GO:0008545 : JUN kinase kinase activity - xref: Reactome:REACT_81103 "Phosphorylation of human JNKs by activated MKK4/MKK7, Saccharomyces cerevisiae" - xref: Reactome:REACT_82185 "Phosphorylation of human JNKs by activated MKK4/MKK7, Caenorhabditis elegans" - xref: Reactome:REACT_31247 "Phosphorylation of human JNKs by activated MKK4/MKK7, Schizosaccharomyces pombe" + xref: Reactome:REACT_114469 "Phosphorylation of human JNKs by activated MKK4/MKK7, Dictyostelium discoideum" + xref: Reactome:REACT_112463 "Phosphorylation of human JNKs by activated MKK4/MKK7, Arabidopsis thaliana" + xref: Reactome:REACT_99661 "Phosphorylation of human JNKs by activated MKK4/MKK7, Caenorhabditis elegans" + xref: Reactome:REACT_114896 "Phosphorylation of human JNKs by activated MKK4/MKK7, Oryza sativa" GO:0008551 : cadmium-exporting ATPase activity - synonym: "cd2+-exporting ATPase activity" EXACT [EC:3.6.3.3] GO:0008555 : chloride-transporting ATPase activity - synonym: "cl--transporting ATPase activity" EXACT [EC:3.6.3.11] GO:0008559 : xenobiotic-transporting ATPase activity + xref: Reactome:REACT_111164 "ABCA8, B1 and B5 mediate xenobiotic efflux, Homo sapiens" GO:0008597 : calcium-dependent protein serine/threonine phosphatase regulator activity + xref: Reactome:REACT_113351 "Activation of BAD by calcineurin, Xenopus tropicalis" + xref: Reactome:REACT_113411 "Activation of BAD by calcineurin, Rattus norvegicus" GO:0008599 : protein phosphatase type 1 regulator activity - xref: Reactome:REACT_32210 "DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function, Bos taurus" + xref: Reactome:REACT_110300 "DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function, Bos taurus" GO:0008609 : alkylglycerone-phosphate synthase activity + xref: Reactome:REACT_114920 "1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate, Escherichia coli" + xref: Reactome:REACT_115040 "1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate, Mycobacterium tuberculosis" GO:0008611 : ether lipid biosynthetic process + xref: Reactome:REACT_112332 "Plasmalogen biosynthesis, Mycobacterium tuberculosis" + xref: Reactome:REACT_112578 "Plasmalogen biosynthesis, Escherichia coli" GO:0008612 : peptidyl-lysine modification to hypusine - xref: Reactome:REACT_99882 "Hypusine synthesis from eIF5A-lysine, Plasmodium falciparum" + xref: Reactome:REACT_114795 "Hypusine synthesis from eIF5A-lysine, Caenorhabditis elegans" GO:0008624 : induction of apoptosis by extracellular signals - xref: Reactome:REACT_101011 "FASL binds FAS Receptor, Bos taurus" + xref: Reactome:REACT_113720 "FasL/ CD95L signaling, Xenopus tropicalis" + xref: Reactome:REACT_114928 "Cell death signalling via NRAGE, NRIF and NADE, Dictyostelium discoideum" + xref: Reactome:REACT_89305 "FASL binds FAS Receptor, Bos taurus" + xref: Reactome:REACT_115331 "FASL binds FAS Receptor, Xenopus tropicalis" + xref: Reactome:REACT_113012 "Extrinsic Pathway for Apoptosis, Caenorhabditis elegans" GO:0008629 : induction of apoptosis by intracellular signals + xref: Reactome:REACT_113789 "Intrinsic Pathway for Apoptosis, Oryza sativa" + xref: Reactome:REACT_114326 "Intrinsic Pathway for Apoptosis, Schizosaccharomyces pombe" + xref: Reactome:REACT_113707 "Intrinsic Pathway for Apoptosis, Drosophila melanogaster" + xref: Reactome:REACT_114288 "Intrinsic Pathway for Apoptosis, Arabidopsis thaliana" + xref: Reactome:REACT_113652 "Intrinsic Pathway for Apoptosis, Dictyostelium discoideum" + xref: Reactome:REACT_114572 "Intrinsic Pathway for Apoptosis, Saccharomyces cerevisiae" GO:0008633 : activation of pro-apoptotic gene products - xref: Reactome:REACT_88970 "Activation of PUMA and translocation to mitochondria, Canis familiaris" + xref: Reactome:REACT_112394 "Activation of NOXA and translocation to mitochondria, Canis familiaris" + xref: Reactome:REACT_115317 "Activation of NOXA and translocation to mitochondria, Mus musculus" + xref: Reactome:REACT_115069 "Activation of BAD and translocation to mitochondria, Xenopus tropicalis" + xref: Reactome:REACT_113401 "Activation of NOXA and translocation to mitochondria, Rattus norvegicus" + xref: Reactome:REACT_112867 "Activation of NOXA and translocation to mitochondria, Sus scrofa" + xref: Reactome:REACT_112824 "Caspase-8 is formed from procaspase-8, Caenorhabditis elegans" + xref: Reactome:REACT_112277 "Granzyme-B activates BID by cleavage, Xenopus tropicalis" + xref: Reactome:REACT_112012 "Activation of BIM and translocation to mitochondria, Xenopus tropicalis" GO:0008635 : activation of caspase activity by cytochrome c + xref: Reactome:REACT_114180 "Activation of caspases through apoptosome-mediated cleavage, Canis familiaris" + xref: Reactome:REACT_111966 "Activation of caspases through apoptosome-mediated cleavage, Bos taurus" + xref: Reactome:REACT_114234 "Activation of caspases through apoptosome-mediated cleavage, Sus scrofa" + xref: Reactome:REACT_113336 "Activation of caspases through apoptosome-mediated cleavage, Rattus norvegicus" GO:0008645 : hexose transport - xref: Reactome:REACT_106522 "Hexose transport, Sus scrofa" + xref: Reactome:REACT_112310 "Hexose transport, Mycobacterium tuberculosis" + xref: Reactome:REACT_77191 "Hexose transport, Sus scrofa" + xref: Reactome:REACT_112026 "Hexose transport, Dictyostelium discoideum" GO:0008652 : cellular amino acid biosynthetic process - xref: Reactome:REACT_104217 "Amino acid synthesis and interconversion (transamination), Sus scrofa" + xref: Reactome:REACT_112051 "Amino acid synthesis and interconversion (transamination), Staphylococcus aureus N315" + xref: Reactome:REACT_31295 "Amino acid synthesis and interconversion (transamination), Sus scrofa" GO:0008725 : DNA-3-methyladenine glycosylase activity - name: DNA-3-methyladenine glycosylase I activity + name: DNA-3-methyladenine glycosylase activity - def: Catalysis of the hydrolysis of alkylated DNA; only recognizes and removes the alkylated base 3-methyladenine by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site. + def: Catalysis of the reaction: DNA containing 3-methyladenine + H2O = DNA with abasic site + 3-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methyladenine and the deoxyribose sugar to remove the 3-methyladenine, leaving an abasic site. + synonym: "DNA-3-methyladenine glycosylase I activity" EXACT [] + xref: EC:3.2.2.21 + xref: MetaCyc:3.2.2.21-RXN - is_a: GO:0003905 + is_a: GO:0043733 GO:0008756 : o-succinylbenzoate-CoA ligase activity - synonym: "osb-CoA synthetase activity" EXACT [EC:6.2.1.26] GO:0008783 : agmatinase activity - xref: Reactome:REACT_86058 "Agmatine + H2O <=> putrescine + urea, Oryza sativa" - xref: Reactome:REACT_108668 "Agmatine + H2O <=> putrescine + urea, Arabidopsis thaliana" - xref: Reactome:REACT_102547 "Agmatine + H2O <=> putrescine + urea, Staphylococcus aureus N315" GO:0008792 : arginine decarboxylase activity - xref: Reactome:REACT_84356 "Arginine<=>Agmatine+CO2, Saccharomyces cerevisiae" + xref: Reactome:REACT_115439 "Arginine<=>Agmatine+CO2, Drosophila melanogaster" + xref: Reactome:REACT_29623 "Arginine<=>Agmatine+CO2, Saccharomyces cerevisiae" + xref: Reactome:REACT_112250 "Arginine<=>Agmatine+CO2, Staphylococcus aureus N315" GO:0008802 : betaine-aldehyde dehydrogenase activity - is_a: GO:0016620 + is_a: GO:0004029 GO:0008810 : cellulase activity - def: Catalysis of the endohydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans. + def: Catalysis of the endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans. GO:0008815 : citrate (pro-3S)-lyase activity - xref: Reactome:REACT_81700 "Generation of Cytoplasmic Acetyl CoA from Citrate, Mycobacterium tuberculosis" + xref: Reactome:REACT_114344 "Generation of Cytoplasmic Acetyl CoA from Citrate, Saccharomyces cerevisiae" + xref: Reactome:REACT_114419 "Generation of Cytoplasmic Acetyl CoA from Citrate, Caenorhabditis elegans" GO:0008843 : endochitinase activity - def: Catalysis of the hydrolysis of nonterminal 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, endochitinases cleave randomly within the chitin chain. + def: Catalysis of the hydrolysis of nonterminal (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, endochitinases cleave randomly within the chitin chain. GO:0008891 : glycolate oxidase activity + xref: Reactome:REACT_114154 "glycolate + O2 => glyoxylate + H2O2, Drosophila melanogaster" + xref: Reactome:REACT_112286 "glycolate + O2 => glyoxylate + H2O2, Oryza sativa" + xref: Reactome:REACT_113804 "glycolate + O2 => glyoxylate + H2O2, Arabidopsis thaliana" + xref: Reactome:REACT_112704 "glycolate + O2 => glyoxylate + H2O2, Dictyostelium discoideum" + xref: Reactome:REACT_113493 "glycolate + O2 => glyoxylate + H2O2, Escherichia coli" + xref: Reactome:REACT_112171 "glycolate + O2 => glyoxylate + H2O2, Mycobacterium tuberculosis" GO:0008897 : holo-[acyl-carrier-protein] synthase activity + xref: Reactome:REACT_114181 "Phosphopantetheine conjugation of the ACP domain of FAS, Xenopus tropicalis" + xref: Reactome:REACT_114029 "Phosphopantetheine conjugation of the ACP domain of FAS, Dictyostelium discoideum" GO:0008900 : hydrogen:potassium-exchanging ATPase activity - synonym: "h+/K+-exchanging ATPase activity" EXACT [EC:3.6.3.10] GO:0008911 : lactaldehyde dehydrogenase activity - is_a: GO:0016620 + is_a: GO:0004029 GO:0008932 : lytic endotransglycosylase activity - def: Catalysis of the specific cleavage of the beta-1,4 glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues. Acts on linkages within peptidoglycan chains (i.e. not at the ends) to produce shorter strands with 1,6-anhydromuramic acid ends. + def: Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues. Acts on linkages within peptidoglycan chains (i.e. not at the ends) to produce shorter strands with 1,6-anhydromuramic acid ends. GO:0008933 : lytic transglycosylase activity - def: Catalysis of the specific cleavage of the beta-1,4 glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues. + def: Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues. GO:0008936 : nicotinamidase activity - synonym: "namase activity" EXACT [EC:3.5.1.19] GO:0008957 : phenylacetaldehyde dehydrogenase activity - is_a: GO:0016620 + is_a: GO:0004029 GO:0009021 : tRNA (uracil-5-)-methyltransferase activity - synonym: "m5U-methyltransferase activity" EXACT [EC:2.1.1.35] GO:0009044 : xylan 1,4-beta-xylosidase activity - def: Catalysis of the hydrolysis of 1,4-beta-D-xylans so as to remove successive D-xylose residues from the non-reducing termini. + def: Catalysis of the hydrolysis of (1->4)-beta-D-xylans so as to remove successive D-xylose residues from the non-reducing termini. GO:0009055 : electron carrier activity - xref: Reactome:REACT_93247 "Reducing equivalents from beta-oxidation of fatty acids transfer to ETF, Saccharomyces cerevisiae" + xref: Reactome:REACT_108215 "Reducing equivalents from beta-oxidation of fatty acids transfer to ETF, Saccharomyces cerevisiae" GO:0009083 : branched chain family amino acid catabolic process - xref: Reactome:REACT_89466 "Branched-chain amino acid catabolism, Sus scrofa" + xref: Reactome:REACT_98686 "Branched-chain amino acid catabolism, Sus scrofa" GO:0009108 : coenzyme biosynthetic process - xref: Reactome:REACT_92003 "Coenzyme A biosynthesis, Caenorhabditis elegans" + xref: Reactome:REACT_107153 "Coenzyme A biosynthesis, Caenorhabditis elegans" GO:0009168 : purine ribonucleoside monophosphate biosynthetic process - xref: Reactome:REACT_102227 "Purine ribonucleoside monophosphate biosynthesis, Sus scrofa" - xref: Reactome:REACT_97778 "Purine ribonucleoside monophosphate biosynthesis, Schizosaccharomyces pombe" + xref: Reactome:REACT_33659 "Purine ribonucleoside monophosphate biosynthesis, Sus scrofa" + xref: Reactome:REACT_92811 "Purine ribonucleoside monophosphate biosynthesis, Schizosaccharomyces pombe" GO:0009692 : ethylene metabolic process + xref: Reactome:REACT_112653 "Ethylene is oxidized to Ethylene oxide by CYP1A1, Gallus gallus" + xref: Reactome:REACT_113841 "Ethylene is oxidized to Ethylene oxide by CYP1A1, Danio rerio" GO:0009804 : coumarin metabolic process - xref: Reactome:REACT_88845 "Coumarin is 7-hydroxylated by CYP2A13, Canis familiaris" - xref: Reactome:REACT_108785 "Coumarin is 7-hydroxylated by CYP2A13, Sus scrofa" + xref: Reactome:REACT_112622 "Coumarin is 7-hydroxylated by CYP2A6, Xenopus tropicalis" + xref: Reactome:REACT_113359 "Coumarin is 7-hydroxylated by CYP2A6, Mus musculus" + xref: Reactome:REACT_113450 "Coumarin is 7-hydroxylated by CYP2A6, Rattus norvegicus" + xref: Reactome:REACT_112822 "Coumarin is 7-hydroxylated by CYP2A6, Danio rerio" GO:0009969 : xyloglucan biosynthetic process - def: The chemical reactions and pathways resulting in the formation of xyloglucan, the cross-linking glycan composed of 1->4-beta-D glucan backbone substituted at regular intervals with beta-D-xylosyl-1->6 residues, which is present in the primary cell wall of most higher plants. + def: The chemical reactions and pathways resulting in the formation of xyloglucan, the cross-linking glycan composed of (1->4)-beta-D glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants. GO:0010021 : amylopectin biosynthetic process - def: The chemical reactions and pathways resulting in the formation of amylopectin, the (1,4) linked alpha glucose units with alpha-(1,6) linkages. + def: The chemical reactions and pathways resulting in the formation of amylopectin, the (1->4) linked alpha glucose units with alpha-(1->6) linkages. GO:0010289 : homogalacturonan biosynthetic process - def: The chemical reactions and pathways resulting in the formation of the pectidic homogalacturonan, characterized by a backbone of 1,4-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3. + def: The chemical reactions and pathways resulting in the formation of the pectidic homogalacturonan, characterized by a backbone of (1->4)-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3. GO:0010397 : apiogalacturonan metabolic process - def: The chemical reactions and pathways involving the pectic apiogalacturonan, characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted with apiose and apiobiose (D-apiofuranosyl-beta-(l->3)-D-apiose) side chains via O-2 or O-3 links. + def: The chemical reactions and pathways involving the pectic apiogalacturonan, characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted with apiose and apiobiose (D-apiofuranosyl-beta-(1->3)-D-apiose) side chains via O-2 or O-3 links. GO:0010402 : pectic arabinan metabolic process - def: The chemical reactions and pathways involving arabinan, a polymer with an alpha-(1->5)-linked -L-arabinofuranose (Araf) backbone that can be substituted with Araf-alpha-(1->2)-, Araf-alpha-(1->3)-, and/or Araf-alpha-(1->3)-Araf-alpha-(1->3)-side chains. Arabinan can be found as a side chain of the pectin rhamnogalacturonan I. + def: The chemical reactions and pathways involving arabinan, a polymer with an alpha-(1->5)-linked L-arabinofuranose (Araf) backbone that can be substituted with Araf-alpha-(1->2)-, Araf-alpha-(1->3)-, and/or Araf-alpha-(1->3)-Araf-alpha-(1->3)-side chains. Arabinan can be found as a side chain of the pectin rhamnogalacturonan I. GO:0010403 : pectic arabinogalactan I metabolic process - def: The chemical reactions and pathways involving pectic arabinogalactan I, an alpha-(1->4)-linked D-galactopyranose backbone that is substituted with alpha-l-Araf residues via the O-3 of the D-galactose residues. Arabinogalactan I can be found as a side chain of rhamnogalacturonan I. + def: The chemical reactions and pathways involving pectic arabinogalactan I, an alpha-(1,4)-linked D-galactopyranose backbone that is substituted with alpha-l-Araf residues via the O-3 of the D-galactose residues. Arabinogalactan I can be found as a side chain of rhamnogalacturonan I. GO:0010465 : nerve growth factor receptor activity + relationship: has_part GO:0048406 GO:0010467 : gene expression - xref: Reactome:REACT_30701 "Gene Expression, Sus scrofa" + xref: Reactome:REACT_101952 "Gene Expression, Sus scrofa" GO:0010493 : Lewis a epitope biosynthetic process - def: The chemical reactions and pathways resulting in the formation of a Lewis a epitope, a trisaccharide (Fuc-alpha-1->4(Gal-beta-1->3)GlcNAc) characteristic of plant protein N-linked oligosaccharides. + def: The chemical reactions and pathways resulting in the formation of a Lewis a epitope, a trisaccharide (Fuc-alpha-(1->4)[Gal-beta-(1->3)]GlcNAc) characteristic of plant protein N-linked oligosaccharides. GO:0010510 : regulation of acetyl-CoA biosynthetic process from pyruvate - xref: Reactome:REACT_28764 "Regulation of pyruvate dehydrogenase (PDH) complex, Schizosaccharomyces pombe" GO:0010706 : biosynthesis of lactosylceramide precursor to ganglioside - def: The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal beta(1,4)Glc beta(1,1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group as a precursor of gangliosides. + def: The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group as a precursor of gangliosides. GO:0010707 : biosynthesis of lactosylceramide precursor to globoside - def: The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal beta(1,4)Glc beta(1,1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group as a precursor of globosides. + def: The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group as a precursor of globosides. GO:0010827 : regulation of glucose transport - xref: Reactome:REACT_102535 "Regulation of Glucokinase by Glucokinase Regulatory Protein, Plasmodium falciparum" - xref: Reactome:REACT_80959 "Regulation of Glucokinase by Glucokinase Regulatory Protein, Drosophila melanogaster" + xref: Reactome:REACT_100137 "Regulation of Glucokinase by Glucokinase Regulatory Protein, Plasmodium falciparum" GO:0010843 : promoter binding + consider: GO:0001047 GO:0010908 : regulation of heparan sulfate proteoglycan biosynthetic process - def: Any process that modulates the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating (alpha1->4)-linked hexuronic acid and glucosamine residues. + def: Any process that modulates the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues. GO:0010909 : positive regulation of heparan sulfate proteoglycan biosynthetic process - def: Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating (alpha1->4)-linked hexuronic acid and glucosamine residues. + def: Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues. GO:0014047 : glutamate secretion - xref: Reactome:REACT_80086 "Glutamate Neurotransmitter Release Cycle, Sus scrofa" + xref: Reactome:REACT_94050 "Glutamate Neurotransmitter Release Cycle, Sus scrofa" + xref: Reactome:REACT_112750 "Glutamate Neurotransmitter Release Cycle, Staphylococcus aureus N315" GO:0015012 : heparan sulfate proteoglycan biosynthetic process - def: The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating (alpha1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues. + def: The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues. GO:0015020 : glucuronosyltransferase activity - synonym: "Phenyl-UDP-glucuronosyltransferase activity" NARROW [EC:2.4.1.17] - xref: Reactome:REACT_85610 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Gallus gallus" - xref: Reactome:REACT_93792 "Formation of O-glucuronides, Gallus gallus" - xref: Reactome:REACT_30191 "Formation of O-glucuronides, Canis familiaris" - xref: Reactome:REACT_82301 "Formation of N-glucuronides, Gallus gallus" - xref: Reactome:REACT_80212 "Formation of N-glucuronides, Drosophila melanogaster" - xref: Reactome:REACT_96677 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Sus scrofa" - xref: Reactome:REACT_96026 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Xenopus tropicalis" - xref: Reactome:REACT_94147 "bilirubin monoglucuronide + UDP-glucuronic acid => bilirubin diglucuronide + UDP, Drosophila melanogaster" - xref: Reactome:REACT_32188 "bilirubin monoglucuronide + UDP-glucuronic acid => bilirubin diglucuronide + UDP, Sus scrofa" - xref: Reactome:REACT_30608 "bilirubin monoglucuronide + UDP-glucuronic acid => bilirubin diglucuronide + UDP, Gallus gallus" - xref: Reactome:REACT_32163 "Formation of O-glucuronides, Drosophila melanogaster" - xref: Reactome:REACT_109506 "bilirubin monoglucuronide + UDP-glucuronic acid => bilirubin diglucuronide + UDP, Xenopus tropicalis" - xref: Reactome:REACT_94974 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Drosophila melanogaster" - xref: Reactome:REACT_79398 "Formation of N-glucuronides, Xenopus tropicalis" - xref: Reactome:REACT_93560 "Formation of O-glucuronides, Xenopus tropicalis" + xref: Reactome:REACT_114051 "Formation of N-glucuronides, Caenorhabditis elegans" + xref: Reactome:REACT_112395 "Formation of O-glucuronides, Caenorhabditis elegans" + xref: Reactome:REACT_96318 "bilirubin monoglucuronide + UDP-glucuronic acid => bilirubin diglucuronide + UDP, Sus scrofa" + xref: Reactome:REACT_96239 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Sus scrofa" + xref: Reactome:REACT_114908 "bilirubin monoglucuronide + UDP-glucuronic acid => bilirubin diglucuronide + UDP, Caenorhabditis elegans" + xref: Reactome:REACT_113946 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Caenorhabditis elegans" GO:0015038 : glutathione disulfide oxidoreductase activity - xref: Reactome:REACT_89210 "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized), Schizosaccharomyces pombe" - xref: Reactome:REACT_106153 "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized), Caenorhabditis elegans" - xref: Reactome:REACT_106063 "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized), Saccharomyces cerevisiae" + xref: Reactome:REACT_31672 "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized), Caenorhabditis elegans" + xref: Reactome:REACT_114108 "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized), Oryza sativa" + xref: Reactome:REACT_112460 "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized), Arabidopsis thaliana" + xref: Reactome:REACT_114787 "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized), Plasmodium falciparum" GO:0015078 : hydrogen ion transmembrane transporter activity - xref: Reactome:REACT_102259 "Enzyme-bound ATP is released, Taeniopygia guttata" GO:0015116 : sulfate transmembrane transporter activity + xref: Reactome:REACT_113041 "Group 1 - Sulphate transport, Plasmodium falciparum" + xref: Reactome:REACT_113869 "Group 1 - Sulphate transport, Dictyostelium discoideum" GO:0015125 : bile acid transmembrane transporter activity - xref: Reactome:REACT_82161 "Transport (influx) of glycocholate and taurocholate by OATP-8, Gallus gallus" - xref: Reactome:REACT_51328 "Transport (influx) of glycocholate and taurocholate by OATP-C, Gallus gallus" - xref: Reactome:REACT_87325 "Transport (influx) of bile salts and acids by OATP-A, Gallus gallus" + xref: Reactome:REACT_114986 "Transport (influx) of glycocholate and taurocholate by OATP-8, Danio rerio" + xref: Reactome:REACT_113507 "Transport (influx) of bile salts and acids by OATP-A, Danio rerio" + xref: Reactome:REACT_114243 "Transport (influx) of glycocholate and taurocholate by OATP-C, Danio rerio" GO:0015129 : lactate transmembrane transporter activity - xref: Reactome:REACT_94399 "lactate + H+ [extracellular] <=> lactate + H+ [cytosol], Bos taurus" - xref: Reactome:REACT_34617 "lactate + H+ [cytosol] <=> lactate + H+ [extracellular], Bos taurus" + xref: Reactome:REACT_113117 "lactate + H+ [extracellular] <=> lactate + H+ [cytosol], Drosophila melanogaster" + xref: Reactome:REACT_101266 "lactate + H+ [cytosol] <=> lactate + H+ [extracellular], Bos taurus" + xref: Reactome:REACT_112882 "lactate + H+ [cytosol] <=> lactate + H+ [extracellular], Drosophila melanogaster" + xref: Reactome:REACT_94824 "lactate + H+ [extracellular] <=> lactate + H+ [cytosol], Bos taurus" GO:0015149 : hexose transmembrane transporter activity + xref: Reactome:REACT_114686 "Transport (efflux) of fructose, galactose, and glucose by GLUT2, Mycobacterium tuberculosis" + xref: Reactome:REACT_112973 "Transport (efflux) of fructose, galactose, and glucose by GLUT2, Arabidopsis thaliana" + xref: Reactome:REACT_112649 "Transport (efflux) of fructose, galactose, and glucose by GLUT2, Caenorhabditis elegans" + xref: Reactome:REACT_115118 "Transport (efflux) of fructose, galactose, and glucose by GLUT2, Plasmodium falciparum" + xref: Reactome:REACT_113207 "Transport (efflux) of fructose, galactose, and glucose by GLUT2, Drosophila melanogaster" + xref: Reactome:REACT_114648 "Transport (efflux) of fructose, galactose, and glucose by GLUT2, Oryza sativa" + xref: Reactome:REACT_112037 "Transport (efflux) of fructose, galactose, and glucose by GLUT2, Dictyostelium discoideum" GO:0015166 : polyol transmembrane transporter activity + xref: Reactome:REACT_112673 "Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6, Sus scrofa" GO:0015171 : amino acid transmembrane transporter activity - xref: Reactome:REACT_33631 "SLC7A7 (y+LAT1)-mediated exchange of extracellular leucine for cytosolic arginine, Drosophila melanogaster" - xref: Reactome:REACT_106510 "SLC38A1 (ATA1)-mediated uptake of neutral amino acids, Sus scrofa" - xref: Reactome:REACT_101173 "SLC6A14-mediated uptake of basic and neutral amino acids and of beta-alanine, Staphylococcus aureus N315" - xref: Reactome:REACT_91747 "SLC7A7 (y+LAT1)-mediated exchange of extracellular leucine for cytosolic arginine, Danio rerio" - xref: Reactome:REACT_100518 "SLC7A9-mediated exchange of extracellular arginine, lysine, or cystine for cytosolic leucine, Staphylococcus aureus N315" - xref: Reactome:REACT_96352 "SLC7A10-mediated uptake of small neutral amino acids, Caenorhabditis elegans" - xref: Reactome:REACT_79511 "SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine, Bos taurus" - xref: Reactome:REACT_95711 "SLC7A9-mediated exchange of extracellular arginine, lysine, or cystine for cytosolic leucine, Bos taurus" - xref: Reactome:REACT_85083 "SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine, Danio rerio" - xref: Reactome:REACT_108146 "SLC7A7 (y+LAT1)-mediated exchange of extracellular leucine for cytosolic arginine, Bos taurus" - xref: Reactome:REACT_100089 "SLC7A8-mediated uptake of neutral amino acids, Caenorhabditis elegans" + xref: Reactome:REACT_112482 "L-Glutamate uptake by neurons, Staphylococcus aureus N315" + xref: Reactome:REACT_112402 "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine, Danio rerio" + xref: Reactome:REACT_112929 "SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids, Dictyostelium discoideum" + xref: Reactome:REACT_114242 "SLC6A14-mediated uptake of basic and neutral amino acids and of beta-alanine, Danio rerio" + xref: Reactome:REACT_113003 "SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids, Staphylococcus aureus N315" + xref: Reactome:REACT_89087 "SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine, Bos taurus" + xref: Reactome:REACT_113174 "SLC38A4 (ATA3)-mediated uptake of arginine and lysine, Xenopus tropicalis" + xref: Reactome:REACT_113752 "SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate, Caenorhabditis elegans" + xref: Reactome:REACT_112274 "SLC7A3 (CAT-3)-mediated uptake of cationic amino acids, Dictyostelium discoideum" + xref: Reactome:REACT_112776 "SLC7A3 (CAT-3)-mediated uptake of cationic amino acids, Mycobacterium tuberculosis" + xref: Reactome:REACT_112963 "L-Glutamate uptake by neurons, Caenorhabditis elegans" + xref: Reactome:REACT_113529 "SLC6A6-mediated uptake of taurine and beta-alanine, Staphylococcus aureus N315" + xref: Reactome:REACT_30219 "SLC38A1 (ATA1)-mediated uptake of neutral amino acids, Sus scrofa" + xref: Reactome:REACT_85083 "SLC7A7 (y+LAT1)-mediated exchange of extracellular leucine for cytosolic arginine, Danio rerio" + xref: Reactome:REACT_115430 "SLC16A10-mediated uptake of aromatic amino acids, Saccharomyces cerevisiae" + xref: Reactome:REACT_114801 "SLC43A1 (LAT3)-mediated uptake of large neutral amino acids, Dictyostelium discoideum" + xref: Reactome:REACT_114141 "SLC6A14-mediated uptake of basic and neutral amino acids and of beta-alanine, Drosophila melanogaster" + xref: Reactome:REACT_113768 "SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine, Staphylococcus aureus N315" + xref: Reactome:REACT_112624 "SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids, Mycobacterium tuberculosis" + xref: Reactome:REACT_91835 "SLC7A9-mediated exchange of extracellular arginine, lysine, or cystine for cytosolic leucine, Bos taurus" + xref: Reactome:REACT_112236 "SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane, Staphylococcus aureus N315" + xref: Reactome:REACT_115089 "SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine, Staphylococcus aureus N315" + xref: Reactome:REACT_114819 "SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids, Dictyostelium discoideum" + xref: Reactome:REACT_114980 "SLC7A9-mediated exchange of extracellular arginine, lysine, or cystine for cytosolic leucine, Sus scrofa" + xref: Reactome:REACT_114291 "SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine, Staphylococcus aureus N315" + xref: Reactome:REACT_34240 "SLC7A7 (y+LAT1)-mediated exchange of extracellular leucine for cytosolic arginine, Bos taurus" + xref: Reactome:REACT_114685 "SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine, Staphylococcus aureus N315" + xref: Reactome:REACT_114502 "SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids, Mycobacterium tuberculosis" + xref: Reactome:REACT_113011 "SLC7A5-mediated uptake of neutral amino acids, Drosophila melanogaster" + xref: Reactome:REACT_112436 "SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane, Staphylococcus aureus N315" + xref: Reactome:REACT_115373 "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine, Staphylococcus aureus N315" + xref: Reactome:REACT_113690 "SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids, Staphylococcus aureus N315" + xref: Reactome:REACT_114768 "SLC7A3 (CAT-3)-mediated uptake of cationic amino acids, Staphylococcus aureus N315" GO:0015172 : acidic amino acid transmembrane transporter activity - xref: Reactome:REACT_29456 "aspartate [mitochondrial matrix] + glutamate [cytosol] => aspartate [cytosol] + glutamate [mitochondrial matrix], Saccharomyces cerevisiae" + xref: Reactome:REACT_83233 "aspartate [mitochondrial matrix] + glutamate [cytosol] => aspartate [cytosol] + glutamate [mitochondrial matrix], Saccharomyces cerevisiae" GO:0015207 : adenine transmembrane transporter activity - xref: Reactome:REACT_87825 "ADP-ATP translocase maintains a high ADP:ATP ratio in the matrix, Caenorhabditis elegans" - xref: Reactome:REACT_28807 "ADP-ATP translocase maintains a high ADP:ATP ratio in the matrix, Sus scrofa" - xref: Reactome:REACT_104265 "ADP-ATP translocase maintains a high ADP:ATP ratio in the matrix, Plasmodium falciparum" - xref: Reactome:REACT_29203 "ADP-ATP translocase maintains a high ADP:ATP ratio in the matrix, Bos taurus" + xref: Reactome:REACT_114818 "ADP-ATP translocase maintains a high ADP:ATP ratio in the matrix, Arabidopsis thaliana" + xref: Reactome:REACT_106927 "ADP-ATP translocase maintains a high ADP:ATP ratio in the matrix, Sus scrofa" + xref: Reactome:REACT_29736 "ADP-ATP translocase maintains a high ADP:ATP ratio in the matrix, Bos taurus" + xref: Reactome:REACT_115148 "ADP-ATP translocase maintains a high ADP:ATP ratio in the matrix, Oryza sativa" GO:0015220 : choline transmembrane transporter activity + xref: Reactome:REACT_113748 "Sodium- and chloride-dependent choline transport by CHT, Staphylococcus aureus N315" + xref: Reactome:REACT_115008 "Transport of Choline, Staphylococcus aureus N315" GO:0015227 : acyl carnitine transporter activity - xref: Reactome:REACT_79062 "Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane, Caenorhabditis elegans" + xref: Reactome:REACT_90417 "Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane, Caenorhabditis elegans" + xref: Reactome:REACT_112186 "Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane, Schizosaccharomyces pombe" GO:0015232 : heme transporter activity - xref: Reactome:REACT_110140 "ABCB7-mediated transport, Danio rerio" - xref: Reactome:REACT_88411 "ABCB7-mediated transport, Bos taurus" - xref: Reactome:REACT_104909 "ABCB7-mediated transport, Schizosaccharomyces pombe" - xref: Reactome:REACT_82495 "ABCB7-mediated transport, Arabidopsis thaliana" - xref: Reactome:REACT_109850 "ABCB7-mediated transport, Drosophila melanogaster" - xref: Reactome:REACT_97806 "ABCB7-mediated transport, Rattus norvegicus" - xref: Reactome:REACT_104882 "ABCB7-mediated transport, Oryza sativa" - xref: Reactome:REACT_106955 "ABCB7-mediated transport, Saccharomyces cerevisiae" - xref: Reactome:REACT_22342 "ABCB7-mediated transport, Homo sapiens" - xref: Reactome:REACT_34709 "ABCB7-mediated transport, Sus scrofa" - xref: Reactome:REACT_77717 "ABCB7-mediated transport, Mus musculus" - xref: Reactome:REACT_29208 "ABCB7-mediated transport, Caenorhabditis elegans" - xref: Reactome:REACT_78473 "ABCB7-mediated transport, Canis familiaris" - xref: Reactome:REACT_100385 "ABCB7-mediated transport, Dictyostelium discoideum" - xref: Reactome:REACT_97364 "ABCB7-mediated transport, Xenopus tropicalis" - xref: Reactome:REACT_105656 "ABCB7-mediated transport, Taeniopygia guttata" - xref: Reactome:REACT_94308 "ABCB7-mediated transport, Gallus gallus" + xref: Reactome:REACT_94308 "ABC7, mABC1 and mABC2 mediate heme transport, Gallus gallus" + xref: Reactome:REACT_105656 "ABC7, mABC1 and mABC2 mediate heme transport, Taeniopygia guttata" + xref: Reactome:REACT_97364 "ABC7, mABC1 and mABC2 mediate heme transport, Xenopus tropicalis" + xref: Reactome:REACT_104909 "ABC7, mABC1 and mABC2 mediate heme transport, Schizosaccharomyces pombe" + xref: Reactome:REACT_109850 "ABC7, mABC1 and mABC2 mediate heme transport, Drosophila melanogaster" + xref: Reactome:REACT_100385 "ABC7, mABC1 and mABC2 mediate heme transport, Dictyostelium discoideum" + xref: Reactome:REACT_78473 "ABC7, mABC1 and mABC2 mediate heme transport, Canis familiaris" + xref: Reactome:REACT_114177 "ABC7, mABC1 and mABC2 mediate heme transport, Staphylococcus aureus N315" + xref: Reactome:REACT_22342 "ABC7, mABC1 and mABC2 mediate heme transport, Homo sapiens" + xref: Reactome:REACT_111156 "MTABC3 transports porphyrin into mitochondria, Homo sapiens" + xref: Reactome:REACT_110140 "ABC7, mABC1 and mABC2 mediate heme transport, Danio rerio" + xref: Reactome:REACT_29208 "ABC7, mABC1 and mABC2 mediate heme transport, Caenorhabditis elegans" + xref: Reactome:REACT_114591 "ABC7, mABC1 and mABC2 mediate heme transport, Plasmodium falciparum" + xref: Reactome:REACT_82495 "ABC7, mABC1 and mABC2 mediate heme transport, Arabidopsis thaliana" + xref: Reactome:REACT_106955 "ABC7, mABC1 and mABC2 mediate heme transport, Saccharomyces cerevisiae" + xref: Reactome:REACT_88411 "ABC7, mABC1 and mABC2 mediate heme transport, Bos taurus" + xref: Reactome:REACT_77717 "ABC7, mABC1 and mABC2 mediate heme transport, Mus musculus" + xref: Reactome:REACT_97806 "ABC7, mABC1 and mABC2 mediate heme transport, Rattus norvegicus" + xref: Reactome:REACT_112680 "ABC7, mABC1 and mABC2 mediate heme transport, Mycobacterium tuberculosis" + xref: Reactome:REACT_34709 "ABC7, mABC1 and mABC2 mediate heme transport, Sus scrofa" + xref: Reactome:REACT_104882 "ABC7, mABC1 and mABC2 mediate heme transport, Oryza sativa" GO:0015248 : sterol transporter activity - xref: Reactome:REACT_107624 "ABCG5:ABCG8-mediated export of cholesterol and phytosterols, Arabidopsis thaliana" - xref: Reactome:REACT_97437 "ABCG5:ABCG8-mediated export of cholesterol and phytosterols, Dictyostelium discoideum" - xref: Reactome:REACT_30246 "ABCG5:ABCG8-mediated export of cholesterol and phytosterols, Oryza sativa" + xref: Reactome:REACT_114568 "ABCG5:ABCG8-mediated export of cholesterol and phytosterols, Mycobacterium tuberculosis" + xref: Reactome:REACT_114596 "ABCG5:ABCG8-mediated export of cholesterol and phytosterols, Drosophila melanogaster" + xref: Reactome:REACT_113802 "ABCG5:ABCG8-mediated export of cholesterol and phytosterols, Saccharomyces cerevisiae" GO:0015250 : water channel activity - xref: Reactome:REACT_107896 "Passive Transport of Water out of Cell by Aquaporin-3, Caenorhabditis elegans" GO:0015291 : secondary active transmembrane transporter activity + xref: Reactome:REACT_114308 "CoA transport across the inner mitochondrial membrane, Arabidopsis thaliana" + xref: Reactome:REACT_113603 "CoA transport across the inner mitochondrial membrane, Xenopus tropicalis" + xref: Reactome:REACT_114125 "CoA transport across the inner mitochondrial membrane, Oryza sativa" GO:0015307 : drug:hydrogen antiporter activity + xref: Reactome:REACT_112833 "MATEs mediate extrusion of xenobiotics, Escherichia coli" + xref: Reactome:REACT_113868 "MATEs mediate extrusion of xenobiotics, Oryza sativa" + xref: Reactome:REACT_114597 "MATEs mediate extrusion of xenobiotics, Dictyostelium discoideum" + xref: Reactome:REACT_113029 "MATEs mediate extrusion of xenobiotics, Schizosaccharomyces pombe" + xref: Reactome:REACT_114825 "MATEs mediate extrusion of xenobiotics, Arabidopsis thaliana" + xref: Reactome:REACT_113149 "MATEs mediate extrusion of xenobiotics, Saccharomyces cerevisiae" GO:0015321 : sodium-dependent phosphate transmembrane transporter activity - xref: Reactome:REACT_83291 "Electroneutral Na+/Pi cotransport, Caenorhabditis elegans" - xref: Reactome:REACT_104031 "Type III Na+/Pi cotransport, Caenorhabditis elegans" - xref: Reactome:REACT_32338 "Electrogenic Na+/Pi cotransport, Caenorhabditis elegans" - xref: Reactome:REACT_32759 "Electroneutral Na+/Pi cotransport, Danio rerio" - xref: Reactome:REACT_84409 "Type I Na+-coupled phosphate co-transport, Dictyostelium discoideum" - xref: Reactome:REACT_87531 "Type III Na+/Pi cotransport, Plasmodium falciparum" + xref: Reactome:REACT_113983 "Type I Na+-coupled phosphate co-transport, Staphylococcus aureus N315" + xref: Reactome:REACT_114049 "Type I Na+-coupled phosphate co-transport, Escherichia coli" + xref: Reactome:REACT_115481 "Type I Na+-coupled phosphate co-transport, Caenorhabditis elegans" + xref: Reactome:REACT_112119 "Type I Na+-coupled phosphate co-transport, Oryza sativa" + xref: Reactome:REACT_85878 "Type III Na+/Pi cotransport, Plasmodium falciparum" + xref: Reactome:REACT_114838 "Type III Na+/Pi cotransport, Mycobacterium tuberculosis" + xref: Reactome:REACT_114542 "Type I Na+-coupled phosphate co-transport, Arabidopsis thaliana" + xref: Reactome:REACT_113455 "Electrogenic Na+/Pi cotransport, Escherichia coli" + xref: Reactome:REACT_112519 "Electroneutral Na+/Pi cotransport, Escherichia coli" GO:0015333 : peptide:hydrogen symporter activity + xref: Reactome:REACT_111949 "Proton-coupled histidine and di-peptide cotransport, Saccharomyces cerevisiae" + xref: Reactome:REACT_114016 "Proton-coupled di- and tri-peptide cotransport, Caenorhabditis elegans" + xref: Reactome:REACT_115385 "Proton-coupled histidine and di-peptide cotransport, Schizosaccharomyces pombe" GO:0015367 : oxoglutarate:malate antiporter activity - xref: Reactome:REACT_30925 "malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix], Drosophila melanogaster" + xref: Reactome:REACT_112909 "malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix], Dictyostelium discoideum" GO:0015368 : calcium:cation antiporter activity + xref: Reactome:REACT_112998 "K+-independent Li+/Ca2+ exchanger transport, Arabidopsis thaliana" + xref: Reactome:REACT_114708 "K+-independent Li+/Ca2+ exchanger transport, Oryza sativa" GO:0015378 : sodium:chloride symporter activity + xref: Reactome:REACT_113205 "Na+/Cl- cotransport, Drosophila melanogaster" + xref: Reactome:REACT_114168 "Na+/Cl- cotransport, Caenorhabditis elegans" GO:0015379 : potassium:chloride symporter activity + xref: Reactome:REACT_114447 "K+/Cl- cotransport, Caenorhabditis elegans" GO:0015385 : sodium:hydrogen antiporter activity + xref: Reactome:REACT_112054 "Na+/H+ exchanger transport (at early endosome membrane), Gallus gallus" GO:0015432 : bile acid-exporting ATPase activity - xref: Reactome:REACT_87263 "Transport (efflux) of bile salts by ABCC3 (MRP3), Sus scrofa" - xref: Reactome:REACT_94139 "Transport (efflux) of bile salts by ABCC3 (MRP3), Rattus norvegicus" - xref: Reactome:REACT_31005 "Transport (efflux) of bile salts by ABCC3 (MRP3), Xenopus tropicalis" - xref: Reactome:REACT_79348 "Transport (efflux) of bile salts by ABCC3 (MRP3), Canis familiaris" - xref: Reactome:REACT_77625 "Transport (efflux) of bile salts by ABCC3 (MRP3), Taeniopygia guttata" - xref: Reactome:REACT_102709 "Transport (efflux) of bile salts by ABCC3 (MRP3), Gallus gallus" - xref: Reactome:REACT_83682 "Transport (efflux) of bile salts by ABCC3 (MRP3), Bos taurus" - xref: Reactome:REACT_93084 "Transport (efflux) of bile salts by ABCC3 (MRP3), Mus musculus" + xref: Reactome:REACT_113836 "Transport (efflux) of bile salts by ABCB11 (bile salt export pump), Arabidopsis thaliana" + xref: Reactome:REACT_114961 "Transport (efflux) of bile salts by ABCB11 (bile salt export pump), Oryza sativa" + xref: Reactome:REACT_112416 "Transport (efflux) of bile salts by ABCB11 (bile salt export pump), Dictyostelium discoideum" + xref: Reactome:REACT_113803 "Transport (efflux) of bile salts by ABCB11 (bile salt export pump), Schizosaccharomyces pombe" + xref: Reactome:REACT_112096 "Transport (efflux) of bile salts by ABCB11 (bile salt export pump), Plasmodium falciparum" GO:0015433 : peptide antigen-transporting ATPase activity + xref: Reactome:REACT_111185 "Translocation of antigenic peptides back to phagosomes via TAP, Homo sapiens" GO:0015444 : magnesium-importing ATPase activity - synonym: "mg2+-importing ATPase activity" EXACT [EC:3.6.3.2] GO:0015464 : acetylcholine receptor activity - is_a: GO:0042166 + relationship: has_part GO:0042166 GO:0015467 : G-protein activated inward rectifier potassium channel activity - xref: Reactome:REACT_90601 "Activation of GIRK/Kir3 Channels, Gallus gallus" + xref: Reactome:REACT_114055 "Activation of GIRK/Kir3 Channels, Xenopus tropicalis" GO:0015538 : sialic acid:hydrogen symporter activity - xref: Reactome:REACT_92908 "Proton-coupled sialic acid co-transport, Dictyostelium discoideum" + xref: Reactome:REACT_114441 "Proton-coupled sialic acid co-transport, Staphylococcus aureus N315" + xref: Reactome:REACT_113008 "Proton-coupled sialic acid co-transport, Xenopus tropicalis" + xref: Reactome:REACT_112212 "Proton-coupled sialic acid co-transport, Escherichia coli" + xref: Reactome:REACT_112268 "Proton-coupled sialic acid co-transport, Caenorhabditis elegans" + xref: Reactome:REACT_114194 "Proton-coupled sialic acid co-transport, Oryza sativa" + xref: Reactome:REACT_113908 "Proton-coupled sialic acid co-transport, Arabidopsis thaliana" GO:0015662 : ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism - xref: Reactome:REACT_90831 "ABCC4 accumulation of dense granule contents, Canis familiaris" - xref: Reactome:REACT_78040 "ABCC4 accumulation of dense granule contents, Xenopus tropicalis" - xref: Reactome:REACT_31429 "ABCC4 accumulation of dense granule contents, Taeniopygia guttata" - xref: Reactome:REACT_104048 "ABCC4 accumulation of dense granule contents, Bos taurus" - xref: Reactome:REACT_84400 "ABCC4 accumulation of dense granule contents, Rattus norvegicus" - xref: Reactome:REACT_97312 "ABCC4 accumulation of dense granule contents, Sus scrofa" GO:0015701 : bicarbonate transport + xref: Reactome:REACT_114123 "Bicarbonate transporters, Dictyostelium discoideum" GO:0015721 : bile acid and bile salt transport + xref: Reactome:REACT_114070 "Recycling of bile acids and salts, Oryza sativa" + xref: Reactome:REACT_113431 "Recycling of bile acids and salts, Plasmodium falciparum" + xref: Reactome:REACT_114193 "Recycling of bile acids and salts, Schizosaccharomyces pombe" + xref: Reactome:REACT_114004 "Recycling of bile acids and salts, Arabidopsis thaliana" + xref: Reactome:REACT_112634 "Recycling of bile acids and salts, Dictyostelium discoideum" + xref: Reactome:REACT_113858 "Recycling of bile acids and salts, Saccharomyces cerevisiae" GO:0015758 : glucose transport - xref: Reactome:REACT_106224 "Glucose transport, Sus scrofa" + xref: Reactome:REACT_79237 "Glucose transport, Sus scrofa" + xref: Reactome:REACT_112521 "Glucose transport, Dictyostelium discoideum" + xref: Reactome:REACT_114803 "Glucose transport, Mycobacterium tuberculosis" GO:0015918 : sterol transport + xref: Reactome:REACT_114213 "Trafficking of dietary sterols, Mycobacterium tuberculosis" + xref: Reactome:REACT_111982 "Trafficking of dietary sterols, Plasmodium falciparum" GO:0015939 : pantothenate metabolic process - xref: Reactome:REACT_56657 "Vitamin B5 (pantothenate) metabolism, Caenorhabditis elegans" + xref: Reactome:REACT_83248 "Vitamin B5 (pantothenate) metabolism, Caenorhabditis elegans" GO:0015949 : nucleobase-containing small molecule interconversion - xref: Reactome:REACT_99360 "Synthesis and interconversion of nucleotide di- and triphosphates, Staphylococcus aureus N315" - xref: Reactome:REACT_99115 "Synthesis and interconversion of nucleotide di- and triphosphates, Sus scrofa" + xref: Reactome:REACT_96776 "Synthesis and interconversion of nucleotide di- and triphosphates, Sus scrofa" GO:0016019 : peptidoglycan receptor activity - is_a: GO:0042834 + relationship: has_part GO:0042834 GO:0016153 : urocanate hydratase activity - xref: Reactome:REACT_95592 "urocanate + H2O => 4-imidazolone-5-propionate, Caenorhabditis elegans" + xref: Reactome:REACT_109123 "urocanate + H2O => 4-imidazolone-5-propionate, Caenorhabditis elegans" GO:0016162 : cellulose 1,4-beta-cellobiosidase activity - def: Catalysis of the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains. + def: Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains. GO:0016175 : superoxide-generating NADPH oxidase activity + xref: Reactome:REACT_111243 "Alkalization of the phagosomal lumen by NOX2, Homo sapiens" + xref: Reactome:REACT_111249 "Uncoupled eNOS favours the formation of superoxide, Homo sapiens" GO:0016232 : HNK-1 sulfotransferase activity - def: Catalysis of the synthesis of the HKK-1 carbohydrate epitope; adds a sulfate group to a precursor, GlcA-beta-(1,3)-Gal-beta-(1,4)-GlcNAc-beta-(1->R), forming sulfo-3GlcA-beta-(1,3)-Gal-beta-(1,4)-GlcNAc-beta-(1->R). + def: Catalysis of the synthesis of the HKK-1 carbohydrate epitope; adds a sulfate group to a precursor, GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R), forming sulfo-3GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R). GO:0016233 : telomere capping - xref: Reactome:REACT_50133 "Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure, Gallus gallus" - xref: Reactome:REACT_106265 "Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure, Gallus gallus" + xref: Reactome:REACT_112263 "Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure, Danio rerio" + xref: Reactome:REACT_115404 "Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure, Canis familiaris" + xref: Reactome:REACT_113641 "Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure, Canis familiaris" + xref: Reactome:REACT_114938 "Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure, Danio rerio" GO:0016255 : attachment of GPI anchor to protein + xref: Reactome:REACT_112166 "Attachment of GPI anchor to uPAR, Xenopus tropicalis" GO:0016267 : O-glycan processing, core 1 - def: The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 1 O-glycan structure, Gal-beta-1->3-GalNAc. + def: The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 1 O-glycan structure, Gal-beta-(1->3)-GalNAc. GO:0016268 : O-glycan processing, core 2 - def: The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 2 O-glycan structure, GlcNAc-beta-1->6(Gal-beta-1->3)-GalNAc. + def: The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 2 O-glycan structure, GlcNAc-beta-(1->6)[Gal-beta-(1->3)]-GalNAc. GO:0016269 : O-glycan processing, core 3 - def: The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 3 O-glycan structure, GlcNAc-beta-1->3-GalNAc. + def: The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 3 O-glycan structure, GlcNAc-beta-(1->3)-GalNAc. GO:0016270 : O-glycan processing, core 4 - def: The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 4 O-glycan structure, GlcNAc-beta-1->6(GlcNAc-beta-1->3)-GalNAc. + def: The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 4 O-glycan structure, GlcNAc-beta-(1->6)[GalNAc-beta-(1->3)]-GalNAc. GO:0016274 : protein-arginine N-methyltransferase activity + xref: Reactome:REACT_112455 "Loading and methylation of Sm proteins onto SMN Complexes, Xenopus tropicalis" GO:0016287 : glycerone-phosphate O-acyltransferase activity + xref: Reactome:REACT_114844 "palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH, Escherichia coli" + xref: Reactome:REACT_114425 "palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH, Mycobacterium tuberculosis" GO:0016290 : palmitoyl-CoA hydrolase activity - synonym: "long-chain fatty-acyl-CoA hydrolase activity" EXACT [] + synonym: "long-chain fatty-acyl-CoA hydrolase activity" BROAD [] - is_a: GO:0016291 + is_a: GO:0047617 GO:0016298 : lipase activity - xref: Reactome:REACT_93242 "cholesterol ester + H2O -> cholesterol + fatty acid, Bos taurus" - xref: Reactome:REACT_101475 "diacylglycerol + H2O -> 2-acylglycerol + fatty acid, Drosophila melanogaster" - xref: Reactome:REACT_108697 "cholesterol ester + H2O -> cholesterol + fatty acid, Drosophila melanogaster" + xref: Reactome:REACT_114396 "cholesterol ester + H2O -> cholesterol + fatty acid, Danio rerio" + xref: Reactome:REACT_90239 "cholesterol ester + H2O -> cholesterol + fatty acid, Bos taurus" + xref: Reactome:REACT_112065 "diacylglycerol + H2O -> 2-acylglycerol + fatty acid, Danio rerio" GO:0016301 : kinase activity - xref: Reactome:REACT_90760 "Phosphorylation of APC component of the destruction complex, Caenorhabditis elegans" - xref: Reactome:REACT_83381 "Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3, Sus scrofa" - xref: Reactome:REACT_105360 "Activation of the Anaphase Promoting Complex (APC) by Plk1, Saccharomyces cerevisiae" - xref: Reactome:REACT_96493 "Phosphorylation (Ser5) of RNA pol II CTD, Canis familiaris" - xref: Reactome:REACT_97280 "Phosphorylation of Cdc25A at Ser-123 in response to DNA damage, Dictyostelium discoideum" - xref: Reactome:REACT_63920 "SOS phosphorylation and dissociation (IRS), Bos taurus" - xref: Reactome:REACT_82945 "Phosphorylation of Cdc25C at Ser216, Danio rerio" - xref: Reactome:REACT_92944 "Autophosphorylation of PAK-2p34 in the activation loop, Dictyostelium discoideum" - xref: Reactome:REACT_105836 "Phosphorylation of 4E-BP1 by activated mTORC1, Rattus norvegicus" - xref: Reactome:REACT_94350 "Phosphorylation of DLC1 by MAPK 8, Mus musculus" - xref: Reactome:REACT_108365 "Phosphorylation of histone H2AX at Serine-139 by ATM at the site of DSB, Arabidopsis thaliana" - xref: Reactome:REACT_84361 "Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197, Dictyostelium discoideum" - xref: Reactome:REACT_31296 "Phosphoryation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3, Caenorhabditis elegans" - xref: Reactome:REACT_91575 "Phosphorylation of L1 by ERK, Schizosaccharomyces pombe" - xref: Reactome:REACT_85906 "Phosphorylation of Cyclin D:Cdk4/6 complexes, Bos taurus" - xref: Reactome:REACT_83893 "Phosphorylation of histone H2AX at Serine-139 by ATM at the site of DSB, Xenopus tropicalis" - xref: Reactome:REACT_79440 "Activation of the Anaphase Promoting Complex (APC) by Plk1, Dictyostelium discoideum" - xref: Reactome:REACT_81185 "Phosphorylation and activation of Chk1 by ATM, Schizosaccharomyces pombe" - xref: Reactome:REACT_94361 "Phosphorylation and activation of CHK2 by ATM, Caenorhabditis elegans" - xref: Reactome:REACT_80221 "Intermolecular autophosphorylation of ATM within dimeric ATM complexes, Caenorhabditis elegans" - xref: Reactome:REACT_79451 "Activation of S6K1, Rattus norvegicus" - xref: Reactome:REACT_80679 "Phosphorylation and activation of Chk1 by ATM, Caenorhabditis elegans" - xref: Reactome:REACT_80177 "CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes, Caenorhabditis elegans" - xref: Reactome:REACT_105371 "Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3, Danio rerio" - xref: Reactome:REACT_110063 "Phosphorylation and activation of eIF4G by activated S6K1, Bos taurus" - xref: Reactome:REACT_100988 "Phosphorylation of histone H2AX at Serine-139 by ATM at the site of DSB, Saccharomyces cerevisiae" - xref: Reactome:REACT_80111 "Cdc6 protein is phosphorylated by CDK, Sus scrofa" - xref: Reactome:REACT_81253 "Inactivation of Myt1 kinase, Saccharomyces cerevisiae" - xref: Reactome:REACT_88476 "Phosphorylation of histone H2AX at Serine-139 by ATM at the site of DSB, Schizosaccharomyces pombe" - xref: Reactome:REACT_102691 "CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes, Bos taurus" - xref: Reactome:REACT_101802 "Phosphorylation of MDM2 at serine-395 by ATM kinase, Sus scrofa" - xref: Reactome:REACT_89430 "CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes, Bos taurus" - xref: Reactome:REACT_87470 "Phosphorylation of beta-catenin at Ser45 by CK1 alpha, Caenorhabditis elegans" - xref: Reactome:REACT_81838 "Phosphorylation of AKT2 by PDK1, Dictyostelium discoideum" - xref: Reactome:REACT_82955 "Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes, Sus scrofa" - xref: Reactome:REACT_79478 "Phosphorylation (Ser5) of RNA pol II CTD, Bos taurus" - xref: Reactome:REACT_30381 "Phosphorylation of beta-catenin at Ser45 by CK1 alpha, Danio rerio" - xref: Reactome:REACT_82583 "SOS phosphorylation and dissociation (SHC), Bos taurus" - xref: Reactome:REACT_78012 "Phosphoryation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3, Danio rerio" - xref: Reactome:REACT_96123 "Phosphorylation and activation of eIF4B by activated S6K1, Rattus norvegicus" - xref: Reactome:REACT_28667 "Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3, Sus scrofa" - xref: Reactome:REACT_77104 "Phosphorylation of beta-catenin at Ser45 by CK1 alpha, Sus scrofa" - xref: Reactome:REACT_96416 "Activation of Cdc25C, Dictyostelium discoideum" - xref: Reactome:REACT_92084 "Phosphoryation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3, Sus scrofa" - xref: Reactome:REACT_109807 "Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3, Caenorhabditis elegans" - xref: Reactome:REACT_31035 "Phosphorylation and inactivation of eEF2K by activated S6K1, Sus scrofa" - xref: Reactome:REACT_92398 "Phosphorylation of PDE3B, Sus scrofa" - xref: Reactome:REACT_106651 "CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes, Sus scrofa" - xref: Reactome:REACT_82555 "Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3, Danio rerio" - xref: Reactome:REACT_79233 "Phosphorylation of histone H2AX at Serine-139 by ATM at the site of DSB, Oryza sativa" - xref: Reactome:REACT_86472 "Phosphorylation of APC component of the destruction complex, Danio rerio" - xref: Reactome:REACT_85274 "Activation of Cdc25C, Danio rerio" - xref: Reactome:REACT_91734 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Bos taurus" - xref: Reactome:REACT_97613 "Phosphorylation of APC component of the destruction complex, Sus scrofa" - xref: Reactome:REACT_100400 "CAK-mediated phosphorylation of Cyclin E:Cdk2, Bos taurus" - xref: Reactome:REACT_94648 "Regulation of NudC by phosphorylation, Schizosaccharomyces pombe" - xref: Reactome:REACT_78393 "Phosphorylation of Cyclin B1 in the CRS domain, Caenorhabditis elegans" - xref: Reactome:REACT_33110 "Phosphorylation (Ser5) of RNA pol II CTD, Schizosaccharomyces pombe" - xref: Reactome:REACT_93474 "Phosphorylation of Cdc25A at Ser-123 by Chk2, Dictyostelium discoideum" - xref: Reactome:REACT_110996 "CAK-mediated phosphorylation of Cyclin A:Cdk2, Bos taurus" - xref: Reactome:REACT_31799 "Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3, Caenorhabditis elegans" - xref: Reactome:REACT_89572 "Phosphorylation of histone H2AX at Serine-139 by ATM at the site of DSB, Drosophila melanogaster" + xref: Reactome:REACT_113569 "Activation of Cdc25C, Saccharomyces cerevisiae" + xref: Reactome:REACT_112101 "Phosphorylation of L1 by CK-II, Xenopus tropicalis" + xref: Reactome:REACT_112892 "Phosphorylation of BRCA1 at multiple sites by ATM, Oryza sativa" + xref: Reactome:REACT_114434 "Autophosphorylation of DNA-PKcs, Taeniopygia guttata" + xref: Reactome:REACT_113435 "Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta, Oryza sativa" + xref: Reactome:REACT_110296 "Phosphorylation and activation of Chk1 by ATM, Schizosaccharomyces pombe" + xref: Reactome:REACT_113051 "Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta, Arabidopsis thaliana" + xref: Reactome:REACT_112360 "Regulation of MKLP-1 by phosphorylation, Dictyostelium discoideum" + xref: Reactome:REACT_114255 "Autophosphorylation of DNA-PKcs, Mus musculus" + xref: Reactome:REACT_86533 "Cdc6 protein is phosphorylated by CDK, Sus scrofa" + xref: Reactome:REACT_113894 "PIP2 conversion to PIP3, Caenorhabditis elegans" + xref: Reactome:REACT_114323 "Activation of Cdc25C, Caenorhabditis elegans" + xref: Reactome:REACT_112270 "Akt1 phosphorylates BAD protein, Xenopus tropicalis" + xref: Reactome:REACT_114624 "Phosphorylation of Cyclin E1:Cdk2 complexes by Myt1, Drosophila melanogaster" + xref: Reactome:REACT_114198 "Phosphorylation of the Scc1:Cohesion Complex, Schizosaccharomyces pombe" + xref: Reactome:REACT_80632 "Phosphorylation of L1 by ERK, Schizosaccharomyces pombe" + xref: Reactome:REACT_114984 "Autophosphorylation of DNA-PKcs, Xenopus tropicalis" + xref: Reactome:REACT_94248 "SOS phosphorylation and dissociation (SHC), Bos taurus" + xref: Reactome:REACT_29759 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Bos taurus" + xref: Reactome:REACT_111124 "FGFR associated PI3K phosphorylates PIP2 to PIP3, Homo sapiens" + xref: Reactome:REACT_114207 "Phosphorylation of Cdc25A at Ser-123 by Chk1, Schizosaccharomyces pombe" + xref: Reactome:REACT_115199 "Autophosphorylation of DNA-PKcs, Canis familiaris" + xref: Reactome:REACT_111930 "Phosphorylation of Cdc25A at Ser-123 by Chk2, Caenorhabditis elegans" + xref: Reactome:REACT_114280 "Phosphorylation of Cdc25A at Ser-123 in response to DNA damage, Saccharomyces cerevisiae" + xref: Reactome:REACT_115384 "CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes, Schizosaccharomyces pombe" + xref: Reactome:REACT_114522 "Phosphorylation of BRCA1 at multiple sites by ATM, Arabidopsis thaliana" + xref: Reactome:REACT_115472 "Phosphorylation of the SA2 Cohesion Complex, Schizosaccharomyces pombe" + xref: Reactome:REACT_113990 "Activation of Cdc25C, Schizosaccharomyces pombe" + xref: Reactome:REACT_79125 "SOS phosphorylation and dissociation (IRS), Bos taurus" + xref: Reactome:REACT_114395 "Phosphorylation of DLC1 by MAPK 8, Xenopus tropicalis" + xref: Reactome:REACT_114461 "Phosphorylation of AKT2 by PDK1, Schizosaccharomyces pombe" + xref: Reactome:REACT_86211 "Activation of the Anaphase Promoting Complex (APC) by Plk1, Saccharomyces cerevisiae" + xref: Reactome:REACT_85449 "Phosphorylation and activation of eIF4G by activated S6K1, Bos taurus" + xref: Reactome:REACT_114233 "Autophosphorylation of DNA-PKcs, Sus scrofa" + xref: Reactome:REACT_114227 "Phosphorylation of Cyclin E1:Cdk2 complexes by Myt1, Schizosaccharomyces pombe" + xref: Reactome:REACT_112075 "Mcm2-7 is phosphorylated by DDK, Drosophila melanogaster" + xref: Reactome:REACT_112545 "Phosphorylation and activation of eIF4G by activated S6K1, Drosophila melanogaster" + xref: Reactome:REACT_114599 "Phosphorylation of TSC2 by PKB, Schizosaccharomyces pombe" + xref: Reactome:REACT_113121 "Phosphorylation and activation of eIF4B by activated S6K1, Schizosaccharomyces pombe" + xref: Reactome:REACT_96877 "Phosphorylation of MDM2 at serine-395 by ATM kinase, Sus scrofa" + xref: Reactome:REACT_113820 "Phosphorylation of Cyclin B1 in the CRS domain, Saccharomyces cerevisiae" + xref: Reactome:REACT_112790 "Phosphorylation of Cdc25A at Ser-123 in response to DNA damage, Caenorhabditis elegans" + xref: Reactome:REACT_83089 "Inactivation of Myt1 kinase, Saccharomyces cerevisiae" + xref: Reactome:REACT_112948 "Autophosphorylation of DNA-PKcs, Rattus norvegicus" + xref: Reactome:REACT_113244 "CAK-mediated phosphorylation of Cyclin E:Cdk2, Drosophila melanogaster" + xref: Reactome:REACT_114771 "Phosphorylation of Ribosomal protein S6 by activated S6K1, Canis familiaris" + xref: Reactome:REACT_115527 "Phosphorylation of Cdc25A at Ser-123 by Chk2, Schizosaccharomyces pombe" + xref: Reactome:REACT_112846 "Phosphorylation of Cyclin E1:Cdk2 complexes by Myt1, Saccharomyces cerevisiae" + xref: Reactome:REACT_112298 "Autophosphorylation of DNA-PKcs, Dictyostelium discoideum" + xref: Reactome:REACT_115135 "Phosphorylation and activation of eIF4G by activated S6K1, Dictyostelium discoideum" + xref: Reactome:REACT_113269 "Activation of S6K1, Saccharomyces cerevisiae" + xref: Reactome:REACT_114160 "CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes, Saccharomyces cerevisiae" + xref: Reactome:REACT_113527 "Autophosphorylation of DNA-PKcs, Bos taurus" + xref: Reactome:REACT_113022 "Phosphorylation of Cyclin B1 in the CRS domain, Schizosaccharomyces pombe" + xref: Reactome:REACT_115358 "Phosphorylation of Cyclin E:Cdk2 complexes by Wee-1, Drosophila melanogaster" + xref: Reactome:REACT_96088 "Phosphorylation of PDE3B, Sus scrofa" + xref: Reactome:REACT_112633 "CAK-mediated phosphorylation of Cyclin E:Cdk2, Saccharomyces cerevisiae" + xref: Reactome:REACT_112413 "Phosphorylation of Cdc25A at Ser-123 by Chk2, Saccharomyces cerevisiae" + xref: Reactome:REACT_114906 "Phosphorylation and activation of eIF4G by activated S6K1, Arabidopsis thaliana" + xref: Reactome:REACT_115475 "CAK-mediated phosphorylation of Cyclin E:Cdk2, Schizosaccharomyces pombe" + xref: Reactome:REACT_113929 "Phosphorylation of Cdc25A at Ser-123 by Chk1, Caenorhabditis elegans" + xref: Reactome:REACT_32906 "Phosphorylation and inactivation of eEF2K by activated S6K1, Sus scrofa" + xref: Reactome:REACT_83110 "Phosphorylation (Ser5) of RNA pol II CTD, Schizosaccharomyces pombe" + xref: Reactome:REACT_112324 "Phosphorylation and activation of eIF4G by activated S6K1, Oryza sativa" + xref: Reactome:REACT_112709 "Phosphorylation of L1 by ERK, Saccharomyces cerevisiae" + xref: Reactome:REACT_111171 "FGFR-associated PI3K phosphorylates PIP2 to PIP3, Homo sapiens" + xref: Reactome:REACT_114319 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Caenorhabditis elegans" + xref: Reactome:REACT_113811 "Phosphorylation of Ribosomal protein S6 by activated S6K1, Bos taurus" + xref: Reactome:REACT_112214 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Schizosaccharomyces pombe" + xref: Reactome:REACT_115168 "Autophosphorylation of DNA-PKcs, Gallus gallus" + xref: Reactome:REACT_115521 "Autophosphorylation of DNA-PKcs, Danio rerio" + xref: Reactome:REACT_112722 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Drosophila melanogaster" + xref: Reactome:REACT_115006 "Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta, Caenorhabditis elegans" + xref: Reactome:REACT_112156 "Phosphorylation of AKT2 by PDK1, Saccharomyces cerevisiae" + xref: Reactome:REACT_113227 "Phosphorylation of Ribosomal protein S6 by activated S6K1, Saccharomyces cerevisiae" + xref: Reactome:REACT_115440 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Danio rerio" + xref: Reactome:REACT_114268 "Phosphorylation of Cdc25A at Ser-123 in response to DNA damage, Schizosaccharomyces pombe" + xref: Reactome:REACT_114553 "Phosphorylation of Cdc25A at Ser-123 by Chk1, Saccharomyces cerevisiae" + xref: Reactome:REACT_97458 "Activation of the Anaphase Promoting Complex (APC) by Plk1, Dictyostelium discoideum" + xref: Reactome:REACT_112480 "Inactivation of Wee1 kinase, Dictyostelium discoideum" GO:0016307 : phosphatidylinositol phosphate kinase activity - def: Catalysis of the phosphorylation of phosphatidylinositol phosphate to produce phosphatidylinositol bisphosphate. + def: Catalysis of the reaction: ATP + a phosphatidylinositol phosphate = ADP + a phosphatidylinositol bisphosphate. - is_a: GO:0004428 + is_a: GO:0016301 GO:0016314 : phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity - xref: Reactome:REACT_77049 "PTEN dephosphorylates PIP3, Caenorhabditis elegans" - xref: Reactome:REACT_109476 "Hydrolysis of PIP3 to PIP2, Sus scrofa" - xref: Reactome:REACT_77912 "Hydrolysis of PIP3 to PI(3,4)P2, Sus scrofa" + xref: Reactome:REACT_82001 "Hydrolysis of PIP3 to PIP2, Sus scrofa" + xref: Reactome:REACT_115120 "PTEN dephosphorylates PIP3, Dictyostelium discoideum" + xref: Reactome:REACT_114681 "Hydrolysis of PIP3 to PIP2, Dictyostelium discoideum" + xref: Reactome:REACT_109496 "Hydrolysis of PIP3 to PI(3,4)P2, Sus scrofa" + xref: Reactome:REACT_103500 "PTEN dephosphorylates PIP3, Caenorhabditis elegans" GO:0016362 : activin receptor activity, type II - xref: Reactome:REACT_87581 "Type II receptor phosphorylates type I receptor, Sus scrofa" + xref: Reactome:REACT_91116 "Type II receptor phosphorylates type I receptor, Sus scrofa" GO:0016402 : pristanoyl-CoA oxidase activity - xref: Reactome:REACT_104641 "(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX2), Dictyostelium discoideum" - xref: Reactome:REACT_99484 "(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX2), Drosophila melanogaster" - xref: Reactome:REACT_31617 "(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX2), Caenorhabditis elegans" + xref: Reactome:REACT_113674 "(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3), Xenopus tropicalis" GO:0016405 : CoA-ligase activity - xref: Reactome:REACT_98425 "benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate, Sus scrofa" - xref: Reactome:REACT_33784 "phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate, Danio rerio" - xref: Reactome:REACT_102995 "benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate, Gallus gallus" - xref: Reactome:REACT_34379 "benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate, Danio rerio" - xref: Reactome:REACT_106980 "phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate, Taeniopygia guttata" - xref: Reactome:REACT_34468 "salicylic acid + Coenzyme A + ATP => salicylate-CoA + AMP + pyrophosphate, Taeniopygia guttata" - xref: Reactome:REACT_83697 "salicylic acid + Coenzyme A + ATP => salicylate-CoA + AMP + pyrophosphate, Sus scrofa" - xref: Reactome:REACT_33833 "benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate, Taeniopygia guttata" - xref: Reactome:REACT_90522 "salicylic acid + Coenzyme A + ATP => salicylate-CoA + AMP + pyrophosphate, Gallus gallus" - xref: Reactome:REACT_93894 "salicylic acid + Coenzyme A + ATP => salicylate-CoA + AMP + pyrophosphate, Danio rerio" - xref: Reactome:REACT_107257 "phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate, Gallus gallus" + xref: Reactome:REACT_113679 "phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate, Dictyostelium discoideum" + xref: Reactome:REACT_112778 "salicylic acid + Coenzyme A + ATP => salicylate-CoA + AMP + pyrophosphate, Dictyostelium discoideum" + xref: Reactome:REACT_91132 "benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate, Sus scrofa" + xref: Reactome:REACT_107383 "salicylic acid + Coenzyme A + ATP => salicylate-CoA + AMP + pyrophosphate, Sus scrofa" + xref: Reactome:REACT_112091 "benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate, Dictyostelium discoideum" GO:0016407 : acetyltransferase activity + xref: Reactome:REACT_115357 "Acetylation of SL1, Xenopus tropicalis" GO:0016463 : zinc-exporting ATPase activity - synonym: "zn2+-exporting ATPase activity" EXACT [EC:3.6.3.5] GO:0016491 : oxidoreductase activity + xref: Reactome:REACT_115316 "palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR1], Drosophila melanogaster" GO:0016493 : C-C chemokine receptor activity - is_a: GO:0019957 + relationship: has_part GO:0019957 GO:0016494 : C-X-C chemokine receptor activity - is_a: GO:0019958 + relationship: has_part GO:0019958 GO:0016495 : C-X3-C chemokine receptor activity - is_a: GO:0019960 + relationship: has_part GO:0019960 GO:0016502 : nucleotide receptor activity + relationship: has_part GO:0000166 GO:0016508 : long-chain-enoyl-CoA hydratase activity - xref: Reactome:REACT_29741 "trans-2,3-dehydrohexacosanoyl-CoA + H2O => 3-hydroxyhexacosanoyl-CoA, Dictyostelium discoideum" - xref: Reactome:REACT_99663 "trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA, Mycobacterium tuberculosis" + xref: Reactome:REACT_107128 "trans-2,3-dehydrohexacosanoyl-CoA + H2O => 3-hydroxyhexacosanoyl-CoA, Dictyostelium discoideum" GO:0016515 : interleukin-13 receptor activity - is_a: GO:0019973 + relationship: has_part GO:0019973 GO:0016517 : interleukin-12 receptor activity - is_a: GO:0019972 + relationship: has_part GO:0019972 GO:0016518 : interleukin-14 receptor activity - is_a: GO:0019974 + relationship: has_part GO:0019974 GO:0016556 : mRNA modification - xref: Reactome:REACT_29993 "mRNA Editing, Sus scrofa" + xref: Reactome:REACT_114458 "mRNA Editing, Schizosaccharomyces pombe" + xref: Reactome:REACT_113194 "mRNA Editing, Caenorhabditis elegans" + xref: Reactome:REACT_114695 "mRNA Editing, Saccharomyces cerevisiae" + xref: Reactome:REACT_29117 "mRNA Editing, Sus scrofa" GO:0016651 : oxidoreductase activity, acting on NADH or NADPH - xref: Reactome:REACT_110665 "Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA, Mycobacterium tuberculosis" GO:0016746 : transferase activity, transferring acyl groups - xref: Reactome:REACT_28750 "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine, Sus scrofa" + xref: Reactome:REACT_99705 "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine, Sus scrofa" + xref: Reactome:REACT_113663 "Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate, Gallus gallus" + xref: Reactome:REACT_115059 "Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate, Gallus gallus" + xref: Reactome:REACT_115499 "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine, Gallus gallus" GO:0016768 : spermine synthase activity - xref: Reactome:REACT_104354 "dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine, Rattus norvegicus" + xref: Reactome:REACT_112099 "dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine, Oryza sativa" + xref: Reactome:REACT_114841 "dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine, Arabidopsis thaliana" + xref: Reactome:REACT_113566 "dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine, Mycobacterium tuberculosis" GO:0016780 : phosphotransferase activity, for other substituted phosphate groups - xref: Reactome:REACT_33481 "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol, Sus scrofa" - xref: Reactome:REACT_79100 "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol, Dictyostelium discoideum" - xref: Reactome:REACT_100281 "mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (acyl-GPI) + diacylglycerol, Sus scrofa" - xref: Reactome:REACT_85831 "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol, Saccharomyces cerevisiae" + xref: Reactome:REACT_111955 "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol, Xenopus tropicalis" + xref: Reactome:REACT_83736 "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol, Saccharomyces cerevisiae" + xref: Reactome:REACT_104119 "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol, Dictyostelium discoideum" + xref: Reactome:REACT_32683 "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol, Sus scrofa" + xref: Reactome:REACT_113237 "(ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI, Saccharomyces cerevisiae" + xref: Reactome:REACT_84128 "mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (acyl-GPI) + diacylglycerol, Sus scrofa" + xref: Reactome:REACT_114047 "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol, Drosophila melanogaster" + xref: Reactome:REACT_113436 "mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (acyl-GPI) + diacylglycerol, Saccharomyces cerevisiae" GO:0016787 : hydrolase activity + xref: Reactome:REACT_111159 "Partial proteolysis of antigen in phagolysosomes, Homo sapiens" GO:0016788 : hydrolase activity, acting on ester bonds - xref: Reactome:REACT_30929 "uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid, Sus scrofa" + xref: Reactome:REACT_112177 "uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid, Xenopus tropicalis" + xref: Reactome:REACT_88314 "uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid, Sus scrofa" GO:0016831 : carboxy-lyase activity - xref: Reactome:REACT_30017 "2-amino-3-carboxymuconate semialdehyde => 2-aminomuconate semialdehyde + CO2, Bos taurus" + xref: Reactome:REACT_30831 "2-amino-3-carboxymuconate semialdehyde => 2-aminomuconate semialdehyde + CO2, Bos taurus" GO:0016860 : intramolecular oxidoreductase activity - xref: Reactome:REACT_88198 "Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA, Bos taurus" + xref: Reactome:REACT_34789 "Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA, Bos taurus" GO:0016887 : ATPase activity + xref: Reactome:REACT_113271 "Trafficking of GluR2-containing AMPA receptors to synapse, Xenopus tropicalis" GO:0016896 : exoribonuclease activity, producing 5'-phosphomonoesters - xref: Reactome:REACT_101255 "Decapping of mRNA by the DCP1-DCP2 Complex, Rattus norvegicus" GO:0016985 : mannan endo-1,4-beta-mannosidase activity - def: Catalysis of the random hydrolysis of 1,4-beta-D-mannosidic linkages in mannans, galactomannans, glucomannans, and galactoglucomannans. + def: Catalysis of the random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans, glucomannans, and galactoglucomannans. GO:0017018 : myosin phosphatase activity - xref: Reactome:REACT_99052 "ATP Hydrolysis By Myosin, Drosophila melanogaster" GO:0017040 : ceramidase activity + xref: Reactome:REACT_112467 "ceramide + H2O <=> stearate + sphingosine [endoplasmic reticulum], Oryza sativa" + xref: Reactome:REACT_115217 "ceramide + H2O <=> stearate + sphingosine [endoplasmic reticulum], Drosophila melanogaster" + xref: Reactome:REACT_112340 "ceramide + H2O <=> stearate + sphingosine [endoplasmic reticulum], Arabidopsis thaliana" + xref: Reactome:REACT_113430 "ceramide + H2O => stearate + sphingosine [Golgi], Oryza sativa" + xref: Reactome:REACT_115458 "ceramide + H2O => stearate + sphingosine [Golgi], Arabidopsis thaliana" + xref: Reactome:REACT_113330 "ceramide + H2O => stearate + sphingosine [Golgi], Dictyostelium discoideum" + xref: Reactome:REACT_114429 "ceramide + H2O <=> stearate + sphingosine [endoplasmic reticulum], Dictyostelium discoideum" GO:0017050 : D-erythro-sphingosine kinase activity + xref: Reactome:REACT_114199 "sphingosine +ATP => sphingosine 1-phosphate + ADP, Caenorhabditis elegans" GO:0017057 : 6-phosphogluconolactonase activity - xref: Reactome:REACT_94359 "D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate, Sus scrofa" + xref: Reactome:REACT_110192 "D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate, Sus scrofa" GO:0017060 : 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity - synonym: "alpha-(1->4)-L-fucosyltransferase activity" EXACT [EC:2.4.1.65] - synonym: "alpha-(1,3/1,4) fucosyltransferase III activity" EXACT [EC:2.4.1.65] - synonym: "blood-group substance Lea-dependent fucosyltransferase" NARROW [EC:2.4.1.65] - synonym: "Lewis FT activity" NARROW [EC:2.4.1.65] - synonym: "FucT-II activity" EXACT [EC:2.4.1.65] - synonym: "blood group Lewis alpha-4-fucosyltransferase" NARROW [EC:2.4.1.65] - synonym: "Lewis blood group alpha-(1->3/4)-fucosyltransferase activity" NARROW [EC:2.4.1.65] - synonym: "blood-group substance Le(a)-dependent fucosyltransferase activity" NARROW [EC:2.4.1.65] - synonym: "alpha-4-L-fucosyltransferase activity" EXACT [EC:2.4.1.65] - synonym: "(Le(a))-dependent (alpha-3/4)-fucosyltransferase activity" NARROW [EC:2.4.1.65] - synonym: "blood group Lewis alpha-4-fucosyltransferase activity" NARROW [EC:2.4.1.65] - synonym: "Lewis(Le) blood group gene-dependent alpha-(1->3/4)-L-fucosyltransferase" NARROW [EC:2.4.1.65] - synonym: "alpha(1,4)-L-fucosyltransferase activity" EXACT [] - synonym: "galactoside 3(4)-L-fucosyltransferase activity" EXACT [] - synonym: "Lewis alpha-(1->3/4)-fucosyltransferase" NARROW [EC:2.4.1.65] - synonym: "Lewis alpha-(1->3/4)-fucosyltransferase activity" NARROW [EC:2.4.1.65] - synonym: "alpha(1,3/1,4) fucosyltransferase III" RELATED [EC:2.4.1.65] - synonym: "Lewis blood group alpha-(1->3/4)-fucosyltransferase" NARROW [EC:2.4.1.65] - synonym: "beta-acetylglucosaminylsaccharide fucosyltransferase activity" EXACT [EC:2.4.1.65] - synonym: "(Lea)-dependent (alpha-3/4)-fucosyltransferase activity" EXACT [EC:2.4.1.65] + synonym: "alpha-(1,3/1,4) fucosyltransferase III activity" BROAD [EC:2.4.1.65] + synonym: "alpha-(1->4)-L-fucosyltransferase activity" BROAD [EC:2.4.1.65] + synonym: "(Lea)-dependent (alpha-3/4)-fucosyltransferase activity" BROAD [EC:2.4.1.65] + synonym: "Lewis(Le) blood group gene-dependent alpha-(1,3/4)-L-fucosyltransferase activity" BROAD [] + synonym: "Lewis FT activity" BROAD [EC:2.4.1.65] + synonym: "blood-group substance Le(a)-dependent fucosyltransferase activity" BROAD [EC:2.4.1.65] + synonym: "Lewis blood group alpha-(1,3/4)-fucosyltransferase activity" BROAD [EC:2.4.1.65] + synonym: "blood-group substance Lea-dependent fucosyltransferase" BROAD [EC:2.4.1.65] + synonym: "blood group Lewis alpha-4-fucosyltransferase activity" BROAD [EC:2.4.1.65] + synonym: "Lewis alpha-(1,3/4)-fucosyltransferase activity" BROAD [EC:2.4.1.65] + synonym: "galactoside 3(4)-L-fucosyltransferase activity" BROAD [] + synonym: "FucT-II activity" BROAD [EC:2.4.1.65] + synonym: "Lewis blood group alpha-(1->3/4)-fucosyltransferase activity" BROAD [EC:2.4.1.65] + synonym: "alpha-(1,4)-L-fucosyltransferase activity" BROAD [EC:2.4.1.65] + synonym: "Lewis alpha-(1->3/4)-fucosyltransferase activity" BROAD [EC:2.4.1.65] + synonym: "(Le(a))-dependent (alpha-3/4)-fucosyltransferase activity" BROAD [EC:2.4.1.65] + synonym: "alpha(1,4)-L-fucosyltransferase activity" BROAD [] + synonym: "alpha-4-L-fucosyltransferase activity" BROAD [EC:2.4.1.65] + synonym: "beta-acetylglucosaminylsaccharide fucosyltransferase activity" BROAD [EC:2.4.1.65] GO:0017081 : chloride channel regulator activity - xref: Reactome:REACT_96291 "HCO3- transport through ion channel, Caenorhabditis elegans" + xref: Reactome:REACT_112601 "HCO3- transport through ion channel, Escherichia coli" GO:0017120 : polyphosphatidylinositol phosphatase activity - def: Catalysis of the conversion of phosphatidylinositol-3-phosphate, phosphatidylinositol-4-phosphate, and phosphatidylinositol-3,5-bisphosphate, but not PI-4,5-bisphosphate, to phosphatidylinositol; PPIPase activity is a key regulator of membrane trafficking and actin cytoskeleton organization. + def: OBSOLETE. Catalysis of the conversion of phosphatidylinositol-3-phosphate, phosphatidylinositol-4-phosphate, and phosphatidylinositol-3,5-bisphosphate, but not PI-4,5-bisphosphate, to phosphatidylinositol; PPIPase activity is a key regulator of membrane trafficking and actin cytoskeleton organization. + comment: This term was made obsolete because it represents a gene product. - is_a: GO:0016791 + is_obsolete: true + consider: GO:0004438 + consider: GO:0034593 + consider: GO:0043812 GO:0017127 : cholesterol transporter activity - xref: Reactome:REACT_109869 "NPC1L1-mediated phytosterol uptake, Drosophila melanogaster" - xref: Reactome:REACT_71556 "NPC1L1-mediated cholesterol uptake, Sus scrofa" - xref: Reactome:REACT_79442 "NPC1L1-mediated cholesterol uptake, Caenorhabditis elegans" - xref: Reactome:REACT_88915 "NPC1L1-mediated cholesterol uptake, Drosophila melanogaster" + xref: Reactome:REACT_113155 "ABCG1-mediated transport of intracellular cholesterol to the cell surface, Taeniopygia guttata" + xref: Reactome:REACT_112797 "NPC1L1-mediated cholesterol uptake, Plasmodium falciparum" + xref: Reactome:REACT_111034 "ABCG4 may mediate cholesterol efflux, Homo sapiens" + xref: Reactome:REACT_84159 "NPC1L1-mediated cholesterol uptake, Caenorhabditis elegans" + xref: Reactome:REACT_113203 "ABCG1-mediated transport of intracellular cholesterol to the cell surface, Xenopus tropicalis" + xref: Reactome:REACT_112970 "NPC1L1-mediated phytosterol uptake, Plasmodium falciparum" + xref: Reactome:REACT_31143 "NPC1L1-mediated cholesterol uptake, Sus scrofa" GO:0017144 : drug metabolic process - xref: Reactome:REACT_80439 "Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI), Xenopus tropicalis" GO:0017187 : peptidyl-glutamic acid carboxylation + xref: Reactome:REACT_113315 "Gamma-carboxylation, transport, and amino-terminal cleavage of proteins, Drosophila melanogaster" GO:0018279 : protein N-linked glycosylation via asparagine - xref: Reactome:REACT_30384 "Synthesis of dolichyl-phosphate-glucose, Schizosaccharomyces pombe" + xref: Reactome:REACT_31319 "Synthesis of dolichyl-phosphate-glucose, Schizosaccharomyces pombe" GO:0018467 : formaldehyde dehydrogenase activity - is_a: GO:0016620 + is_a: GO:0004029 GO:0018474 : 2-carboxybenzaldehyde dehydrogenase activity - is_a: GO:0016620 + is_a: GO:0004029 GO:0018477 : benzaldehyde dehydrogenase (NADP+) activity - is_a: GO:0016620 + is_a: GO:0033721 GO:0018479 : benzaldehyde dehydrogenase (NAD+) activity - is_a: GO:0016620 + is_a: GO:0004029 GO:0018484 : 4-hydroxybenzaldehyde dehydrogenase activity - is_a: GO:0016620 + is_a: GO:0004029 GO:0018485 : salicylaldehyde dehydrogenase activity - is_a: GO:0016620 + is_a: GO:0004029 GO:0018564 : carbazole 1,9a-dioxygenase activity + synonym: "carbazole 1,9alpha-dioxygenase activity" EXACT [] GO:0018771 : 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity - name: 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase activity + name: 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity - def: Catalysis of the reaction: 2-hydroxy-6-keto-nona-2,4-dienedioate + OH- = cis-2-hydroxypenta-2,4-dienoate + succinate. + def: Catalysis of the reaction: (2E,4Z)-2-hydroxy-6-oxonona-2,4-dienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + H+ + succinate. + synonym: "(2E,4Z)-2-hydroxy-6-oxona-2,4-dienedioate succinylhydrolase activity" EXACT systematic_synonym [EC:3.7.1.14] + synonym: "2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase activity" EXACT [UM-BBD_reactionID:r0438] - xref: EC:3.7.1.- - xref: UM-BBD_enzymeID:e0310 + xref: EC:3.7.1.14 + xref: UM-BBD_reactionID:r0438 + xref: MetaCyc:MHPCHYDROL-RXN + xref: RHEA:24792 GO:0018885 : carbon tetrachloride metabolic process - xref: Reactome:REACT_104637 "Dehalogenation of carbon tetrachloride to form a free radical, Sus scrofa" - xref: Reactome:REACT_31583 "Dehalogenation of carbon tetrachloride to form a free radical, Xenopus tropicalis" + xref: Reactome:REACT_32769 "Dehalogenation of carbon tetrachloride to form a free radical, Sus scrofa" GO:0018910 : benzene metabolic process - xref: Reactome:REACT_101063 "Benzene is hydroxylated to phenol, Xenopus tropicalis" - xref: Reactome:REACT_55692 "Benzene is hydroxylated to phenol, Sus scrofa" + xref: Reactome:REACT_31871 "Benzene is hydroxylated to phenol, Sus scrofa" GO:0019001 : guanyl nucleotide binding - xref: Reactome:REACT_76983 "eEF1A complexes with GTP, Xenopus tropicalis" - xref: Reactome:REACT_84736 "eEF1A complexes with GTP, Sus scrofa" - xref: Reactome:REACT_99590 "eEF1A complexes with GTP, Saccharomyces cerevisiae" - xref: Reactome:REACT_90492 "eEF1A complexes with GTP, Taeniopygia guttata" - xref: Reactome:REACT_98519 "eEF1A complexes with GTP, Oryza sativa" - xref: Reactome:REACT_87810 "eEF1A complexes with GTP, Arabidopsis thaliana" - xref: Reactome:REACT_84177 "eEF1A complexes with GTP, Caenorhabditis elegans" + xref: Reactome:REACT_106634 "eEF1A complexes with GTP, Saccharomyces cerevisiae" GO:0019104 : DNA N-glycosylase activity - xref: Reactome:REACT_85718 "Cleavage of ethenocytosine by TDG glycosylase, Schizosaccharomyces pombe" + xref: Reactome:REACT_104604 "Cleavage of ethenocytosine by TDG glycosylase, Schizosaccharomyces pombe" GO:0019107 : myristoyltransferase activity - xref: Reactome:REACT_100750 "Myristoylation of tBID by NMT1, Bos taurus" + xref: Reactome:REACT_32161 "Myristoylation of tBID by NMT1, Bos taurus" GO:0019108 : aryl-aldehyde dehydrogenase (NAD) activity - is_a: GO:0016620 + is_a: GO:0004029 GO:0019115 : benzaldehyde dehydrogenase activity - is_a: GO:0016620 + is_a: GO:0004030 GO:0019135 : deoxyhypusine monooxygenase activity - xref: Reactome:REACT_92455 "EIF5A(Dhp) + O2 => EIF5A(Hyp), Plasmodium falciparum" + xref: Reactome:REACT_114901 "EIF5A(Dhp) + O2 => EIF5A(Hyp), Caenorhabditis elegans" GO:0019140 : inositol 3-kinase activity - is_a: GO:0004428 + is_a: GO:0016301 GO:0019145 : aminobutyraldehyde dehydrogenase activity - is_a: GO:0016620 + is_a: GO:0004029 GO:0019187 : beta-1,4-mannosyltransferase activity - def: Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming a beta-1,4-linkage. + def: Catalysis of the transfer of a mannose residue to an oligosaccharide, forming a beta-(1->4) linkage. GO:0019206 : nucleoside kinase activity - xref: Reactome:REACT_82505 "cytidine or uridine + ATP => CMP or UMP + ADP [UCK2], Danio rerio" - xref: Reactome:REACT_81871 "cytidine or uridine + ATP => CMP or UMP + ADP [UCK2], Sus scrofa" - xref: Reactome:REACT_91512 "cytidine or uridine + ATP => CMP or UMP + ADP [UCK1], Drosophila melanogaster" + xref: Reactome:REACT_112294 "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP [AK5], Caenorhabditis elegans" + xref: Reactome:REACT_113383 "(d)AMP or (d)CMP + ATP <=> (d)ADP or (d)CDP + ADP [AK5], Caenorhabditis elegans" + xref: Reactome:REACT_114962 "(d)AMP or (d)CMP + ATP <=> (d)ADP or (d)CDP + ADP [AK5], Xenopus tropicalis" + xref: Reactome:REACT_114509 "deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2], Oryza sativa" + xref: Reactome:REACT_100134 "cytidine or uridine + ATP => CMP or UMP + ADP [UCK2], Sus scrofa" + xref: Reactome:REACT_114837 "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP [AK5], Xenopus tropicalis" + xref: Reactome:REACT_112935 "thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1], Arabidopsis thaliana" + xref: Reactome:REACT_115045 "cytidine or uridine + ATP => CMP or UMP + ADP [UCK1], Oryza sativa" + xref: Reactome:REACT_112874 "cytidine or uridine + ATP => CMP or UMP + ADP [UCK1], Arabidopsis thaliana" + xref: Reactome:REACT_112710 "cytidine or uridine + ATP => CMP or UMP + ADP [UCK1], Dictyostelium discoideum" + xref: Reactome:REACT_113048 "cytidine or uridine + ATP => CMP or UMP + ADP [UCK1], Drosophila melanogaster" + xref: Reactome:REACT_113816 "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP [AK5], Escherichia coli" + xref: Reactome:REACT_113015 "(d)AMP or (d)CMP + ATP <=> (d)ADP or (d)CDP + ADP [AK5], Escherichia coli" + xref: Reactome:REACT_113689 "deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2], Arabidopsis thaliana" GO:0019244 : lactate biosynthetic process from pyruvate + synonym: "pyruvate fermentation to lactate" EXACT [] GO:0019246 : L(+)-lactate biosynthetic process from pyruvate - def: The chemical reactions and pathways resulting in the formation of L(+)lactate from other compounds, including pyruvate. + def: The chemical reactions and pathways resulting in the formation of L(+)-lactate from other compounds, including pyruvate. + synonym: "S-lactate biosynthetic process from pyruvate" EXACT [] + xref: MetaCyc:PWY-5481 GO:0019370 : leukotriene biosynthetic process + xref: Reactome:REACT_113490 "Leukotriene synthesis, Mycobacterium tuberculosis" GO:0019388 : galactose catabolic process - xref: Reactome:REACT_92286 "Galactose catabolism, Sus scrofa" + xref: Reactome:REACT_33886 "Galactose catabolism, Sus scrofa" GO:0019432 : triglyceride biosynthetic process - xref: Reactome:REACT_96275 "Triglyceride Biosynthesis, Schizosaccharomyces pombe" + xref: Reactome:REACT_81530 "Triglyceride Biosynthesis, Schizosaccharomyces pombe" GO:0019433 : triglyceride catabolic process + xref: Reactome:REACT_115465 "Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis, Staphylococcus aureus N315" + xref: Reactome:REACT_112141 "Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis, Oryza sativa" + xref: Reactome:REACT_114503 "Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis, Arabidopsis thaliana" GO:0019674 : NAD metabolic process - xref: Reactome:REACT_80887 "Nicotinate metabolism, Dictyostelium discoideum" + xref: Reactome:REACT_105395 "Nicotinate metabolism, Dictyostelium discoideum" GO:0019763 : immunoglobulin receptor activity - is_a: GO:0019865 + relationship: has_part GO:0019865 GO:0019766 : IgA receptor activity - is_a: GO:0019862 + relationship: has_part GO:0019862 GO:0019767 : IgE receptor activity - is_a: GO:0019863 + relationship: has_part GO:0019863 GO:0019770 : IgG receptor activity - is_a: GO:0019864 + relationship: has_part GO:0019864 GO:0019825 : oxygen binding - xref: Reactome:REACT_104903 "CYP4F12 hydroxylates arachidonic acid, Bos taurus" - xref: Reactome:REACT_87157 "CYP4F8 hydroxylates prostaglandin H2, Canis familiaris" - xref: Reactome:REACT_108791 "CYP3A5 oxidises aflatoxin B1 to aflatoxin-8,9-oxide, Rattus norvegicus" - xref: Reactome:REACT_79362 "CYP4F2 omega-hydroxylates leukotriene B4, thus inactivating it, Bos taurus" - xref: Reactome:REACT_100468 "MEOS oxidizes ethanol to acetaldehyde, Xenopus tropicalis" - xref: Reactome:REACT_98733 "CYP4F12 hydroxylates arachidonic acid, Canis familiaris" - xref: Reactome:REACT_108293 "CYP3A7 can 6beta-hydroxylate testosterone, Bos taurus" - xref: Reactome:REACT_105335 "CYP3A4 can N-demethylate loperaminde, Caenorhabditis elegans" - xref: Reactome:REACT_91396 "CYP3A4 can N-demethylate loperaminde, Bos taurus" - xref: Reactome:REACT_98613 "CYP2U1 can omega-hydroxylate arachidonate, Caenorhabditis elegans" - xref: Reactome:REACT_92861 "CYP4F3 omega-hydroxylates leukotriene B4, thus inactivating it, Bos taurus" - xref: Reactome:REACT_30377 "CYP4F12 hydroxylates arachidonic acid, Sus scrofa" - xref: Reactome:REACT_104637 "Dehalogenation of carbon tetrachloride to form a free radical, Sus scrofa" - xref: Reactome:REACT_97637 "CYP2C19 5-hydroxylates omeprazole, Xenopus tropicalis" - xref: Reactome:REACT_82285 "CYP3A7 can 6beta-hydroxylate testosterone, Canis familiaris" - xref: Reactome:REACT_103342 "N-hydroxylation of 4-aminobiphenyl, Bos taurus" - xref: Reactome:REACT_28328 "CYP3A5 oxidises aflatoxin B1 to aflatoxin-8,9-oxide, Caenorhabditis elegans" - xref: Reactome:REACT_31583 "Dehalogenation of carbon tetrachloride to form a free radical, Xenopus tropicalis" - xref: Reactome:REACT_80439 "Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI), Xenopus tropicalis" - xref: Reactome:REACT_54494 "CYP3A4 can N-demethylate loperaminde, Rattus norvegicus" - xref: Reactome:REACT_28179 "CYP3A7 can 6beta-hydroxylate testosterone, Rattus norvegicus" - xref: Reactome:REACT_98611 "CYP3A4 can N-demethylate loperaminde, Canis familiaris" - xref: Reactome:REACT_106170 "Vinyl chloride is oxidized to 2-Chloroethylene oxide, Sus scrofa" - xref: Reactome:REACT_104205 "CYP2U1 can omega-hydroxylate arachidonate, Drosophila melanogaster" - xref: Reactome:REACT_79520 "CYP4F2 omega-hydroxylates leukotriene B4, thus inactivating it, Canis familiaris" - xref: Reactome:REACT_105192 "CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation, Xenopus tropicalis" - xref: Reactome:REACT_101063 "Benzene is hydroxylated to phenol, Xenopus tropicalis" - xref: Reactome:REACT_107892 "S-atom dealkylation of 6-methylmercaptopurine, Sus scrofa" - xref: Reactome:REACT_55692 "Benzene is hydroxylated to phenol, Sus scrofa" - xref: Reactome:REACT_87584 "CYP3A5 oxidises aflatoxin B1 to aflatoxin-8,9-oxide, Canis familiaris" - xref: Reactome:REACT_83612 "CYP3A5 oxidises aflatoxin B1 to aflatoxin-8,9-oxide, Bos taurus" - xref: Reactome:REACT_85590 "CYP4F8 hydroxylates prostaglandin H2, Bos taurus" - xref: Reactome:REACT_92591 "Vinyl chloride is oxidized to 2-Chloroethylene oxide, Xenopus tropicalis" - xref: Reactome:REACT_92887 "CYP4F2 omega-hydroxylates leukotriene B4, thus inactivating it, Sus scrofa" - xref: Reactome:REACT_97585 "Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide, Xenopus tropicalis" - xref: Reactome:REACT_102873 "CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation, Xenopus tropicalis" - xref: Reactome:REACT_94199 "CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation, Xenopus tropicalis" - xref: Reactome:REACT_106014 "CYP3A7 can 6beta-hydroxylate testosterone, Caenorhabditis elegans" + xref: Reactome:REACT_113292 "N-hydroxylation of 4-aminobiphenyl, Danio rerio" + xref: Reactome:REACT_31871 "Benzene is hydroxylated to phenol, Sus scrofa" + xref: Reactome:REACT_93076 "Vinyl chloride is oxidized to 2-Chloroethylene oxide, Sus scrofa" + xref: Reactome:REACT_112331 "S-atom dealkylation of 6-methylmercaptopurine, Danio rerio" + xref: Reactome:REACT_113220 "CYP3A5 oxidises aflatoxin B1 to aflatoxin-8,9-oxide, Taeniopygia guttata" + xref: Reactome:REACT_79087 "N-hydroxylation of 4-aminobiphenyl, Bos taurus" + xref: Reactome:REACT_112900 "N-atom dealkylation of caffeine, Gallus gallus" + xref: Reactome:REACT_102736 "S-atom dealkylation of 6-methylmercaptopurine, Sus scrofa" + xref: Reactome:REACT_112751 "CYP1B1 4-hydroxylates estradiol-17beta, Danio rerio" + xref: Reactome:REACT_112032 "CYP3A4 can N-demethylate loperaminde, Taeniopygia guttata" + xref: Reactome:REACT_32769 "Dehalogenation of carbon tetrachloride to form a free radical, Sus scrofa" + xref: Reactome:REACT_112653 "Ethylene is oxidized to Ethylene oxide by CYP1A1, Gallus gallus" + xref: Reactome:REACT_33304 "CYP4F3 omega-hydroxylates leukotriene B4, thus inactivating it, Bos taurus" + xref: Reactome:REACT_113841 "Ethylene is oxidized to Ethylene oxide by CYP1A1, Danio rerio" + xref: Reactome:REACT_112584 "S-atom dealkylation of 6-methylmercaptopurine, Gallus gallus" + xref: Reactome:REACT_114039 "N-hydroxylation of 4-aminobiphenyl, Gallus gallus" + xref: Reactome:REACT_114317 "CYP3A7 can 6beta-hydroxylate testosterone, Taeniopygia guttata" + xref: Reactome:REACT_112347 "N-atom dealkylation of caffeine, Danio rerio" GO:0022416 : chaeta development - name: bristle development + name: chaeta development - def: The process whose specific outcome is the progression of the bristle over time, from its formation to the mature structure. A bristle is an insect sensory organ. + def: The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell. + synonym: "bristle development" NARROW [GOC:bf, GOC:dos] GO:0022803 : passive transmembrane transporter activity - xref: Reactome:REACT_30399 "Passive I- efflux mediated by SMCT1, Gallus gallus" - xref: Reactome:REACT_84103 "Passive I- efflux mediated by SMCT1, Danio rerio" - xref: Reactome:REACT_91343 "Passive I- efflux mediated by SMCT1, Rattus norvegicus" - xref: Reactome:REACT_108557 "Passive I- efflux mediated by SMCT1, Xenopus tropicalis" - xref: Reactome:REACT_96728 "Passive I- efflux mediated by SMCT1, Staphylococcus aureus N315" - xref: Reactome:REACT_90623 "Passive I- efflux mediated by SMCT1, Bos taurus" - xref: Reactome:REACT_105657 "Passive I- efflux mediated by SMCT1, Sus scrofa" - xref: Reactome:REACT_86462 "Passive I- efflux mediated by SMCT1, Mus musculus" - xref: Reactome:REACT_95668 "Passive I- efflux mediated by SMCT1, Canis familiaris" - xref: Reactome:REACT_31260 "Passive I- efflux mediated by SMCT1, Taeniopygia guttata" GO:0022857 : transmembrane transporter activity - xref: Reactome:REACT_80497 "GLUT9 transports glucose, fructose and urate, Drosophila melanogaster" + xref: Reactome:REACT_113829 "GLUT9 transports glucose, fructose and urate, Arabidopsis thaliana" + xref: Reactome:REACT_114161 "GLUT9 transports glucose, fructose and urate, Oryza sativa" + xref: Reactome:REACT_111933 "GLUT9 transports glucose, fructose and urate, Plasmodium falciparum" + xref: Reactome:REACT_113047 "GLUT9 transports glucose, fructose and urate, Dictyostelium discoideum" + xref: Reactome:REACT_113116 "GLUT9 transports glucose, fructose and urate, Mycobacterium tuberculosis" + xref: Reactome:REACT_111088 "Egress of internalized antigen to the cytosol via sec61, Homo sapiens" GO:0030060 : L-malate dehydrogenase activity - xref: Reactome:REACT_97973 "Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+, Oryza sativa" - xref: Reactome:REACT_97671 "(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+, Arabidopsis thaliana" - xref: Reactome:REACT_29753 "(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+, Oryza sativa" - xref: Reactome:REACT_100902 "Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+, Saccharomyces cerevisiae" - xref: Reactome:REACT_92950 "Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+, Arabidopsis thaliana" - xref: Reactome:REACT_91255 "(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+, Saccharomyces cerevisiae" GO:0030168 : platelet activation - xref: Reactome:REACT_29092 "Platelet Activation, Caenorhabditis elegans" - xref: Reactome:REACT_88938 "Platelet Activation, Gallus gallus" - xref: Reactome:REACT_109042 "Platelet Activation, Arabidopsis thaliana" - xref: Reactome:REACT_83720 "Platelet Activation, Dictyostelium discoideum" - xref: Reactome:REACT_28166 "Platelet Activation, Rattus norvegicus" - xref: Reactome:REACT_86767 "Platelet Activation, Taeniopygia guttata" - xref: Reactome:REACT_82375 "Platelet Activation, Sus scrofa" - xref: Reactome:REACT_97013 "Platelet Activation, Plasmodium falciparum" - xref: Reactome:REACT_108920 "Platelet Activation, Saccharomyces cerevisiae" - xref: Reactome:REACT_88667 "Platelet Activation, Drosophila melanogaster" - xref: Reactome:REACT_105599 "Platelet Activation, Danio rerio" - xref: Reactome:REACT_85922 "Platelet Activation, Canis familiaris" - xref: Reactome:REACT_103583 "Platelet Activation, Mus musculus" - xref: Reactome:REACT_92635 "Platelet Activation, Oryza sativa" - xref: Reactome:REACT_32211 "Platelet Activation, Bos taurus" - xref: Reactome:REACT_100921 "Platelet Activation, Escherichia coli" - xref: Reactome:REACT_96250 "Platelet Activation, Schizosaccharomyces pombe" - xref: Reactome:REACT_798 "Platelet Activation, Homo sapiens" - xref: Reactome:REACT_29357 "Platelet Activation, Staphylococcus aureus N315" - xref: Reactome:REACT_82964 "Platelet Activation, Mycobacterium tuberculosis" - xref: Reactome:REACT_86968 "Platelet Activation, Xenopus tropicalis" + xref: Reactome:REACT_88938 "Platelet activation, signaling and aggregation, Gallus gallus" + xref: Reactome:REACT_105599 "Platelet activation, signaling and aggregation, Danio rerio" + xref: Reactome:REACT_86767 "Platelet activation, signaling and aggregation, Taeniopygia guttata" + xref: Reactome:REACT_86968 "Platelet activation, signaling and aggregation, Xenopus tropicalis" + xref: Reactome:REACT_108920 "Platelet activation, signaling and aggregation, Saccharomyces cerevisiae" + xref: Reactome:REACT_83720 "Platelet activation, signaling and aggregation, Dictyostelium discoideum" + xref: Reactome:REACT_82964 "Platelet activation, signaling and aggregation, Mycobacterium tuberculosis" + xref: Reactome:REACT_109042 "Platelet activation, signaling and aggregation, Arabidopsis thaliana" + xref: Reactome:REACT_29357 "Platelet activation, signaling and aggregation, Staphylococcus aureus N315" + xref: Reactome:REACT_97013 "Platelet activation, signaling and aggregation, Plasmodium falciparum" + xref: Reactome:REACT_32211 "Platelet activation, signaling and aggregation, Bos taurus" + xref: Reactome:REACT_28166 "Platelet activation, signaling and aggregation, Rattus norvegicus" + xref: Reactome:REACT_798 "Platelet activation, signaling and aggregation, Homo sapiens" + xref: Reactome:REACT_92635 "Platelet activation, signaling and aggregation, Oryza sativa" + xref: Reactome:REACT_103583 "Platelet activation, signaling and aggregation, Mus musculus" + xref: Reactome:REACT_29092 "Platelet activation, signaling and aggregation, Caenorhabditis elegans" + xref: Reactome:REACT_96250 "Platelet activation, signaling and aggregation, Schizosaccharomyces pombe" + xref: Reactome:REACT_85922 "Platelet activation, signaling and aggregation, Canis familiaris" + xref: Reactome:REACT_82375 "Platelet activation, signaling and aggregation, Sus scrofa" + xref: Reactome:REACT_88667 "Platelet activation, signaling and aggregation, Drosophila melanogaster" GO:0030200 : heparan sulfate proteoglycan catabolic process - def: The chemical reactions and pathways resulting in the breakdown of proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha1->4 linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups. + def: The chemical reactions and pathways resulting in the breakdown of proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4) linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups. GO:0030201 : heparan sulfate proteoglycan metabolic process - def: The chemical reactions and pathways involving any proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha1->4 linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups. + def: The chemical reactions and pathways involving any proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups. GO:0030202 : heparin metabolic process - def: The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha1->4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. + def: The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. GO:0030210 : heparin biosynthetic process - def: The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha1->4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. + def: The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. GO:0030211 : heparin catabolic process - def: The chemical reactions and pathways resulting in the breakdown of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha1->4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. + def: The chemical reactions and pathways resulting in the breakdown of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. GO:0030226 : apolipoprotein receptor activity - is_a: GO:0034185 + relationship: has_part GO:0034185 GO:0030228 : lipoprotein particle receptor activity - is_a: GO:0071813 + relationship: has_part GO:0071813 GO:0030229 : very-low-density lipoprotein particle receptor activity - is_a: GO:0034189 + relationship: has_part GO:0034189 GO:0030267 : glyoxylate reductase (NADP) activity - xref: Reactome:REACT_104358 "glyoxylate + NADPH + H+ => glycolate + NADP+, Sus scrofa" - xref: Reactome:REACT_103015 "glyoxylate + NADPH + H+ => glycolate + NADP+, Saccharomyces cerevisiae" + xref: Reactome:REACT_29565 "glyoxylate + NADPH + H+ => glycolate + NADP+, Sus scrofa" GO:0030342 : 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity - xref: Reactome:REACT_103292 "CYP24A1 catalyzes the initial step in the deactivation of the hormonally active form of vitamin D3, Caenorhabditis elegans" - xref: Reactome:REACT_108673 "1,25-dihydroxyvitamin D3 is deactivated, Caenorhabditis elegans" GO:0030368 : interleukin-17 receptor activity - is_a: GO:0019975 + relationship: has_part GO:0019975 GO:0030412 : formimidoyltetrahydrofolate cyclodeaminase activity - xref: Reactome:REACT_94892 "N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate, Bos taurus" + xref: Reactome:REACT_103744 "N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate, Bos taurus" GO:0030429 : kynureninase activity - synonym: "l-kynurenine hydrolase activity" EXACT [EC:3.7.1.3] + xref: Reactome:REACT_114922 "3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine, Xenopus tropicalis" GO:0030491 : heteroduplex formation - xref: Reactome:REACT_817 "Heteroduplex formation, Homo sapiens" - xref: Reactome:REACT_881 "Synaptic stable pairing/D-loop structure formation between recombining DNA molecules, Homo sapiens" GO:0030509 : BMP signaling pathway - xref: Reactome:REACT_107985 "Signaling by BMP, Caenorhabditis elegans" GO:0030512 : negative regulation of transforming growth factor beta receptor signaling pathway - xref: Reactome:REACT_93061 "I-SMAD competes with R-SMAD for type I receptor, Xenopus tropicalis" - xref: Reactome:REACT_6909 "I-SMAD competes with R-SMAD for type I receptor, Homo sapiens" - xref: Reactome:REACT_82804 "I-SMAD competes with R-SMAD for type I receptor, Canis familiaris" - xref: Reactome:REACT_105250 "I-SMAD competes with R-SMAD for type I receptor, Danio rerio" - xref: Reactome:REACT_90968 "I-SMAD competes with R-SMAD for type I receptor, Rattus norvegicus" - xref: Reactome:REACT_81179 "I-SMAD competes with R-SMAD for type I receptor, Mus musculus" - xref: Reactome:REACT_93800 "I-SMAD competes with R-SMAD for type I receptor, Bos taurus" - xref: Reactome:REACT_95269 "I-SMAD competes with R-SMAD for type I receptor, Sus scrofa" + xref: Reactome:REACT_6909 "I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1), Homo sapiens" + xref: Reactome:REACT_82804 "I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1), Canis familiaris" + xref: Reactome:REACT_95269 "I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1), Sus scrofa" + xref: Reactome:REACT_105250 "I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1), Danio rerio" + xref: Reactome:REACT_113798 "SKI complexes with the SMAD complex, suppressing TGF-beta signaling, Danio rerio" + xref: Reactome:REACT_81179 "I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1), Mus musculus" + xref: Reactome:REACT_93061 "I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1), Xenopus tropicalis" + xref: Reactome:REACT_90968 "I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1), Rattus norvegicus" + xref: Reactome:REACT_93800 "I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1), Bos taurus" GO:0030594 : neurotransmitter receptor activity - is_a: GO:0042165 + relationship: has_part GO:0042165 GO:0030676 : Rac guanyl-nucleotide exchange factor activity + xref: Reactome:REACT_112997 "Activation of Rac1 by FARP2, Xenopus tropicalis" GO:0030776 : (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity - synonym: "(rs)-tetrahydrobenzylisoquinoline N-methyltransferase activity" EXACT [EC:2.1.1.115] GO:0030785 : [ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity - synonym: "rubisco methyltransferase activity" EXACT [EC:2.1.1.127] GO:0031018 : endocrine pancreas development - xref: Reactome:REACT_84766 "Regulation of beta-cell development, Plasmodium falciparum" - xref: Reactome:REACT_97063 "Regulation of gene expression in beta cells, Dictyostelium discoideum" + xref: Reactome:REACT_79285 "Regulation of gene expression in beta cells, Dictyostelium discoideum" + xref: Reactome:REACT_112937 "Regulation of gene expression in beta cells, Mycobacterium tuberculosis" + xref: Reactome:REACT_114067 "Regulation of beta-cell development, Mycobacterium tuberculosis" + xref: Reactome:REACT_80121 "Regulation of beta-cell development, Plasmodium falciparum" GO:0031041 : O-glycan processing, core 5 - def: The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 5 O-glycan structure, GalNAc-alpha-1->3-GalNAc. + def: The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 5 O-glycan structure, GalNAc-alpha-(1->3)-GalNAc. GO:0031042 : O-glycan processing, core 6 - def: The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 6 O-glycan structure, GlcNAc-beta-1->6-GalNAc. + def: The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 6 O-glycan structure, GlcNAc-beta-(1->6)-GalNAc. GO:0031043 : O-glycan processing, core 7 - def: The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 7 O-glycan structure, GalNAc-alpha-1->6-GalNAc. + def: The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 7 O-glycan structure, GalNAc-alpha-(1->6)-GalNAc. GO:0031044 : O-glycan processing, core 8 - def: The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 8 O-glycan structure, Gal-alpha-1->3-GalNAc. + def: The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 8 O-glycan structure, Gal-alpha-(1->3)-GalNAc. GO:0031071 : cysteine desulfurase activity - synonym: "NifS" RELATED [EC:2.8.1.7] GO:0031124 : mRNA 3'-end processing - xref: Reactome:REACT_33629 "mRNA 3'-end processing, Rattus norvegicus" + xref: Reactome:REACT_115007 "mRNA 3'-end processing, Oryza sativa" + xref: Reactome:REACT_114937 "mRNA 3'-end processing, Arabidopsis thaliana" + xref: Reactome:REACT_113053 "mRNA 3'-end processing, Caenorhabditis elegans" + xref: Reactome:REACT_112683 "mRNA 3'-end processing, Drosophila melanogaster" GO:0031127 : alpha-(1,2)-fucosyltransferase activity - name: alpha(1,2)-fucosyltransferase activity + name: alpha-(1,2)-fucosyltransferase activity - def: Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha(1,2)-linkage. + def: Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->2) linkage. + synonym: "alpha-(1->2)-fucosyltransferase activity" EXACT [] + synonym: "alpha-1,2-fucosyltransferase activity" EXACT [] GO:0031145 : anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process - xref: Reactome:REACT_80330 "APC/C-mediated degradation of cell cycle proteins, Caenorhabditis elegans" - xref: Reactome:REACT_89027 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A, Arabidopsis thaliana" - xref: Reactome:REACT_94347 "APC/C:Cdc20 mediated degradation of Securin, Arabidopsis thaliana" + xref: Reactome:REACT_114974 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A, Oryza sativa" GO:0031176 : endo-1,4-beta-xylanase activity - def: Catalysis of the endohydrolysis of 1,4-beta-D-xylosidic linkages in xylans. + def: Catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans. - synonym: "endo-1,4-b-xylanase activity" EXACT [] + synonym: "endo-(1,4)-beta-xylanase(1,4)-beta-xylan 4-xylanohydrolase activity" EXACT [EC:3.2.1.8] GO:0031217 : glucan 1,4-beta-glucosidase activity - def: Catalysis of the hydrolysis of 1,4-linkages in 1,4-beta-D-glucans, to remove successive glucose units. + def: Catalysis of the hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans, to remove successive glucose units. GO:0031218 : arabinogalactan endo-1,4-beta-galactosidase activity - def: Catalysis of the endohydrolysis of 1,4-beta-D-galactosidic linkages in arabinogalactans. + def: Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in arabinogalactans. GO:0031295 : T cell costimulation - xref: Reactome:REACT_30717 "Costimulation by the CD28 family, Dictyostelium discoideum" - xref: Reactome:REACT_92669 "CD28 co-stimulation, Dictyostelium discoideum" - xref: Reactome:REACT_103203 "CD28 co-stimulation, Schizosaccharomyces pombe" + xref: Reactome:REACT_34507 "CD28 co-stimulation, Schizosaccharomyces pombe" GO:0031551 : regulation of brain-derived neurotrophic factor-activated receptor activity - is_a: GO:0043393 GO:0031552 : negative regulation of brain-derived neurotrophic factor-activated receptor activity - is_a: GO:0032091 GO:0031553 : positive regulation of brain-derived neurotrophic factor-activated receptor activity - is_a: GO:0032092 GO:0031581 : hemidesmosome assembly - xref: Reactome:REACT_80480 "Type I hemidesmosome assembly, Drosophila melanogaster" - xref: Reactome:REACT_99612 "Type I hemidesmosome assembly, Caenorhabditis elegans" + xref: Reactome:REACT_112964 "Type I hemidesmosome assembly, Taeniopygia guttata" + xref: Reactome:REACT_113284 "Type I hemidesmosome assembly, Xenopus tropicalis" GO:0032001 : 1,4-alpha-glucan 6-alpha-glucosyltransferase activity - def: Catalysis of the transfer an alpha-D-glucosyl residue in a 1,4-alpha-D-glucan to the primary hydroxy group of glucose, free or combined in a 1,4-alpha-D-glucan. + def: Catalysis of the transfer an alpha-D-glucosyl residue in a (1->4)-alpha-D-glucan to the primary hydroxy group of glucose, free or combined in a (1->4)-alpha-D-glucan. GO:0032259 : methylation - xref: Reactome:REACT_82195 "Methylation, Plasmodium falciparum" GO:0032393 : MHC class I receptor activity + relationship: has_part GO:0042288 GO:0032394 : MHC class Ib receptor activity + relationship: has_part GO:0023029 GO:0032395 : MHC class II receptor activity + relationship: has_part GO:0042289 GO:0032952 : regulation of (1->3)-beta-D-glucan metabolic process - name: regulation of 1,3-beta-D-glucan metabolic process + name: regulation of (1->3)-beta-D-glucan metabolic process - def: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving beta-1,3 glucans. + def: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-beta-D-glucans. + synonym: "regulation of 1,3-beta-D-glucan metabolic process" EXACT [] + synonym: "regulation of (1->3)-beta-D-glucan metabolism" EXACT [] GO:0032953 : regulation of (1->3)-beta-D-glucan biosynthetic process - name: regulation of 1,3-beta-D-glucan biosynthetic process + name: regulation of (1->3)-beta-D-glucan biosynthetic process - def: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta-1,3 glucans. + def: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans. GO:0033164 : glycolipid 6-alpha-mannosyltransferase activity - def: Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-1,6-D-mannosyl-D-mannose linkage. + def: Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->6)-D-mannosyl-D-mannose linkage. + synonym: "GDP-mannose:oligosaccharide 6-alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.232] GO:0033188 : sphingomyelin synthase activity - xref: Reactome:REACT_84431 "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS1], Sus scrofa" - xref: Reactome:REACT_28466 "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS2], Caenorhabditis elegans" - xref: Reactome:REACT_108706 "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS1], Caenorhabditis elegans" + xref: Reactome:REACT_88038 "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS1], Sus scrofa" GO:0033300 : dehydroascorbic acid transporter activity + xref: Reactome:REACT_112507 "Dehydroascorbate transport across the plasma membrane, Mycobacterium tuberculosis" + xref: Reactome:REACT_112481 "Dehydroascorbate transport across the plasma membrane, Arabidopsis thaliana" + xref: Reactome:REACT_114727 "Dehydroascorbate transport across the plasma membrane, Plasmodium falciparum" + xref: Reactome:REACT_113721 "Dehydroascorbate transport across the plasma membrane, Oryza sativa" + xref: Reactome:REACT_112454 "Dehydroascorbate transport across the plasma membrane, Dictyostelium discoideum" + xref: Reactome:REACT_112492 "Dehydroascorbate transport across the plasma membrane, Caenorhabditis elegans" + xref: Reactome:REACT_111999 "Dehydroascorbate transport across the plasma membrane, Drosophila melanogaster" GO:0033560 : folate reductase activity - xref: Reactome:REACT_78107 "Folate is reduced to dihydrofolate (DHF), Saccharomyces cerevisiae" + xref: Reactome:REACT_112030 "Folate is reduced to dihydrofolate (DHF), Staphylococcus aureus N315" + xref: Reactome:REACT_115392 "DHF is reduced to tetrahydrofolate (THF), Dictyostelium discoideum" + xref: Reactome:REACT_78748 "Folate is reduced to dihydrofolate (DHF), Saccharomyces cerevisiae" + xref: Reactome:REACT_114371 "Folate is reduced to dihydrofolate (DHF), Escherichia coli" + xref: Reactome:REACT_112218 "DHF is reduced to tetrahydrofolate (THF), Staphylococcus aureus N315" + xref: Reactome:REACT_114850 "DHF is reduced to tetrahydrofolate (THF), Escherichia coli" + xref: Reactome:REACT_114217 "Folate is reduced to dihydrofolate (DHF), Dictyostelium discoideum" GO:0033723 : fluoroacetaldehyde dehydrogenase activity - is_a: GO:0016620 + is_a: GO:0004029 GO:0033745 : L-methionine-(R)-S-oxide reductase activity - synonym: "fRMsr" RELATED [EC:1.8.4.14] GO:0033778 : 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity + xref: Reactome:REACT_112283 "4-Cholesten-7alpha,27-diol-3-one is 12alpha-hydroxylated to 4-Cholesten-7alpha,12alpha,27-triol-3-one, Dictyostelium discoideum" + xref: Reactome:REACT_114278 "4-Cholesten-7alpha,24(S)-diol-3-one is 12alpha-hydroxylated to 4-cholesten-7-alpha,12-alpha,24(S)-triol-3-one, Arabidopsis thaliana" + xref: Reactome:REACT_113628 "4-Cholesten-7alpha-ol-3-one is 12alpha-hydroxylated to 7-alpha,12-alpha-dihydroxycholest-4-en-3-one, Arabidopsis thaliana" + xref: Reactome:REACT_114957 "4-Cholesten-7alpha,24(S)-diol-3-one is 12alpha-hydroxylated to 4-cholesten-7-alpha,12-alpha,24(S)-triol-3-one, Mycobacterium tuberculosis" + xref: Reactome:REACT_115216 "4-Cholesten-7alpha,27-diol-3-one is 12alpha-hydroxylated to 4-Cholesten-7alpha,12alpha,27-triol-3-one, Arabidopsis thaliana" + xref: Reactome:REACT_114416 "4-Cholesten-7alpha-ol-3-one is 12alpha-hydroxylated to 7-alpha,12-alpha-dihydroxycholest-4-en-3-one, Oryza sativa" + xref: Reactome:REACT_115030 "4-Cholesten-7alpha-ol-3-one is 12alpha-hydroxylated to 7-alpha,12-alpha-dihydroxycholest-4-en-3-one, Dictyostelium discoideum" + xref: Reactome:REACT_115313 "4-Cholesten-7alpha,24(S)-diol-3-one is 12alpha-hydroxylated to 4-cholesten-7-alpha,12-alpha,24(S)-triol-3-one, Oryza sativa" + xref: Reactome:REACT_115001 "4-Cholesten-7alpha-ol-3-one is 12alpha-hydroxylated to 7-alpha,12-alpha-dihydroxycholest-4-en-3-one, Mycobacterium tuberculosis" + xref: Reactome:REACT_114554 "4-Cholesten-7alpha,27-diol-3-one is 12alpha-hydroxylated to 4-Cholesten-7alpha,12alpha,27-triol-3-one, Oryza sativa" + xref: Reactome:REACT_114504 "4-Cholesten-7alpha,24(S)-diol-3-one is 12alpha-hydroxylated to 4-cholesten-7-alpha,12-alpha,24(S)-triol-3-one, Dictyostelium discoideum" GO:0033781 : cholesterol 24-hydroxylase activity - xref: Reactome:REACT_90474 "Cholesterol is hydroxylated to 24-hydroxycholesterol by CYP46A1, Mycobacterium tuberculosis" - xref: Reactome:REACT_87342 "Cholesterol is hydroxylated to 24-hydroxycholesterol by CYP46A1, Arabidopsis thaliana" - xref: Reactome:REACT_100143 "Cholesterol is hydroxylated to 24-hydroxycholesterol by CYP46A1, Drosophila melanogaster" - xref: Reactome:REACT_100082 "Cholesterol is hydroxylated to 24-hydroxycholesterol by CYP46A1, Saccharomyces cerevisiae" GO:0033903 : endo-1,3(4)-beta-glucanase activity - synonym: "endo-beta-(1-3)-D-glucanase activity" BROAD [EC:3.2.1.6] + synonym: "endo-beta-(1,3)-D-glucanase activity" BROAD [EC:3.2.1.6] GO:0033905 : xylan endo-1,3-beta-xylosidase activity - def: Catalysis of the random hydrolysis of 1,3-beta-D-glycosidic linkages in 1,3-beta-D-xylans. + def: Catalysis of the random hydrolysis of (1->3)-beta-D-glycosidic linkages in (1->3)-beta-D-xylans. GO:0033910 : glucan 1,4-alpha-maltotetraohydrolase activity - def: Catalysis of the hydrolysis of 1,4-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotetraose residues from the non-reducing chain ends. + def: Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotetraose residues from the non-reducing chain ends. GO:0033912 : 2,6-beta-fructan 6-levanbiohydrolase activity - def: Catalysis of the hydrolysis of 2,6-beta-D-fructofuranan, to remove successive disaccharide residues as levanbiose, i.e. 6-(beta-D-fructofuranosyl)-D-fructose, from the end of the chain. + def: Catalysis of the hydrolysis of (2->6)-beta-D-fructofuranan, to remove successive disaccharide residues as levanbiose, i.e. 6-(beta-D-fructofuranosyl)-D-fructose, from the end of the chain. GO:0033913 : glucan endo-1,2-beta-glucosidase activity - def: Catalysis of the random hydrolysis of 1,2-glucosidic linkages in 1,2-beta-D-glucans. + def: Catalysis of the random hydrolysis of (1->2)-glucosidic linkages in (1->2)-beta-D-glucans. GO:0033914 : xylan 1,3-beta-xylosidase activity - def: Catalysis of the hydrolysis of successive xylose residues from the non-reducing termini of 1,3-beta-D-xylans. + def: Catalysis of the hydrolysis of successive xylose residues from the non-reducing termini of (1->3)-beta-D-xylans. GO:0033915 : mannan 1,2-(1,3)-alpha-mannosidase activity - def: Catalysis of the hydrolysis of 1,2- and 1,3-linkages in mannan, releasing mannose. + def: Catalysis of the hydrolysis of (1->2) and (1->3) linkages in mannan, releasing mannose. GO:0033916 : beta-agarase activity - def: Catalysis of the hydrolysis of 1,4-beta-D-galactosidic linkages in agarose, giving the tetramer as the predominant product. + def: Catalysis of the hydrolysis of (1->4)-beta-D-galactosidic linkages in agarose, giving the tetramer as the predominant product. GO:0033919 : glucan 1,3-alpha-glucosidase activity - def: Catalysis of the hydrolysis of terminal 1,3-alpha-D-glucosidic links in 1,3-alpha-D-glucans. + def: Catalysis of the hydrolysis of terminal (1->3)-alpha-D-glucosidic links in 1,3-alpha-D-glucans. GO:0033921 : capsular-polysaccharide endo-1,3-alpha-galactosidase activity - def: Catalysis of the random hydrolysis of 1,3-alpha-D-galactosidic linkages in Aerobacter aerogenes capsular polysaccharide. + def: Catalysis of the random hydrolysis of (1->3)-alpha-D-galactosidic linkages in Aerobacter aerogenes capsular polysaccharide. GO:0033923 : glucan 1,6-alpha-isomaltosidase activity - def: Catalysis of the hydrolysis of 1,6-alpha-D-glucosidic linkages in polysaccharides, to remove successive isomaltose units from the non-reducing ends of the chains. + def: Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in polysaccharides, to remove successive isomaltose units from the non-reducing ends of the chains. GO:0033924 : dextran 1,6-alpha-isomaltotriosidase activity - def: Catalysis of the hydrolysis of 1,6-alpha-D-glucosidic linkages in dextrans, to remove successive isomaltotriose units from the non-reducing ends of the chains. + def: Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in dextrans, to remove successive isomaltotriose units from the non-reducing ends of the chains. GO:0033927 : glucan 1,4-alpha-maltohexaosidase activity - def: Catalysis of the hydrolysis of 1,4-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltohexaose residues from the non-reducing chain ends. + def: Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltohexaose residues from the non-reducing chain ends. GO:0033928 : mannan 1,4-mannobiosidase activity - def: Catalysis of the hydrolysis of 1,4-beta-D-mannosidic linkages in 1,4-beta-D-mannans, to remove successive mannobiose residues from the non-reducing chain ends. + def: Catalysis of the hydrolysis of (1->4)-beta-D-mannosidic linkages in (1->4)-beta-D-mannans, to remove successive mannobiose residues from the non-reducing chain ends. GO:0033929 : blood-group-substance endo-1,4-beta-galactosidase activity - def: Catalysis of the endohydrolysis of 1,4-beta-D-galactosidic linkages in blood group A and B substances. + def: Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in blood group A and B substances. GO:0033930 : keratan-sulfate endo-1,4-beta-galactosidase activity - def: Catalysis of the endohydrolysis of 1,4-beta-D-galactosidic linkages in keratan sulfate. + def: Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in keratan sulfate. GO:0033931 : endogalactosaminidase activity - def: Catalysis of the endohydrolysis of 1,4-alpha-D-galactosaminidic linkages in poly(D-galactosamine). + def: Catalysis of the endohydrolysis of (1->4)-alpha-D-galactosaminidic linkages in poly(D-galactosamine). GO:0033932 : 1,3-alpha-L-fucosidase activity - def: Catalysis of the hydrolysis of 1,3-linkages between alpha-L-fucose and N-acetylglucosamine residues in glycoproteins. + def: Catalysis of the hydrolysis of (1->3) linkages between alpha-L-fucose and N-acetylglucosamine residues in glycoproteins. GO:0033933 : branched-dextran exo-1,2-alpha-glucosidase activity - def: Catalysis of the hydrolysis of 1,2-alpha-D-glucosidic linkages at the branch points of dextrans and related polysaccharides, producing free D-glucose. + def: Catalysis of the hydrolysis of (1->2)-alpha-D-glucosidic linkages at the branch points of dextrans and related polysaccharides, producing free D-glucose. GO:0033934 : glucan 1,4-alpha-maltotriohydrolase activity - def: Catalysis of the hydrolysis of 1,4-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotriose residues from the non-reducing chain ends. + def: Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotriose residues from the non-reducing chain ends. GO:0033935 : oligoxyloglucan beta-glycosidase activity - def: Catalysis of the hydrolysis of 1,4-beta-D-glucosidic links in oligoxyloglucans so as to remove successive isoprimeverose (i.e. alpha-xylo-1,6-beta-D-glucosyl-) residues from the non-reducing chain ends. + def: Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic links in oligoxyloglucans so as to remove successive isoprimeverose (i.e. alpha-xylo-1,6-beta-D-glucosyl-) residues from the non-reducing chain ends. GO:0033938 : 1,6-alpha-L-fucosidase activity - def: Catalysis of the hydrolysis of 1,6-linkages between alpha-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin. + def: Catalysis of the hydrolysis of (1->6) linkages between alpha-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin. GO:0033939 : xylan alpha-1,2-glucuronosidase activity - def: Catalysis of the hydrolysis of alpha-D-1,2-(4-O-methyl)glucuronosyl links in the main chain of hardwood xylans. + def: Catalysis of the hydrolysis of alpha-D-(1->2)-(4-O-methyl)glucuronosyl links in the main chain of hardwood xylans. GO:0033940 : glucuronoarabinoxylan endo-1,4-beta-xylanase activity - def: Catalysis of the endohydrolysis of 1,4-beta-D-xylosyl links in some glucuronoarabinoxylans. + def: Catalysis of the endohydrolysis of (1->4)-beta-D-xylosyl links in some glucuronoarabinoxylans. GO:0033941 : mannan exo-1,2-1,6-alpha-mannosidase activity - def: Catalysis of the hydrolysis of 1,2-alpha-D- and 1,6-alpha-D- linkages in mannan, releasing D-mannose. + def: Catalysis of the hydrolysis of (1->2)-alpha-D- and (1->6)-alpha-D- linkages in mannan, releasing D-mannose. GO:0033942 : 4-alpha-D-\{(1->4)-alpha-D-glucano}trehalose trehalohydrolase activity + synonym: "4-alpha-D-{(1,4)-alpha-D-glucano}trehalose glucanohydrolase (trehalose-producing) activity" EXACT [EC:3.2.1.141] GO:0033943 : galactan 1,3-beta-galactosidase activity + synonym: "galactan (1,3)-beta-D-galactosidase activity" EXACT [EC:3.2.1.145] GO:0033945 : oligoxyloglucan reducing-end-specific cellobiohydrolase activity - def: Catalysis of the hydrolysis of cellobiose from the reducing end of xyloglucans consisting of a beta-1,4-linked glucan carrying alpha-D-xylosyl groups on O-6 of the glucose residues. To be a substrate, the first residue must be unsubstituted, the second residue may bear a xylosyl group, whether further glycosylated or not, and the third residue, which becomes the new terminus by the action of the enzyme, is preferably xylosylated, but this xylose residue must not be further substituted. + def: Catalysis of the hydrolysis of cellobiose from the reducing end of xyloglucans consisting of a beta-(1->4) linked glucan carrying alpha-D-xylosyl groups on O-6 of the glucose residues. To be a substrate, the first residue must be unsubstituted, the second residue may bear a xylosyl group, whether further glycosylated or not, and the third residue, which becomes the new terminus by the action of the enzyme, is preferably xylosylated, but this xylose residue must not be further substituted. GO:0033946 : xyloglucan-specific endo-beta-1,4-glucanase activity - def: Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the endohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan. + def: Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the endohydrolysis of (1->4)-beta-D-glucosidic linkages in xyloglucan. GO:0033948 : fructan beta-(2,1)-fructosidase activity - def: Catalysis of the hydrolysis of terminal, non-reducing 2,1-linked beta-D-fructofuranose residues in fructans. + def: Catalysis of the hydrolysis of terminal, non-reducing (2->1) linked beta-D-fructofuranose residues in fructans. - synonym: "beta-(2-1)-linkage-specific fructan-beta-fructosidase activity" EXACT [EC:3.2.1.153] - synonym: "beta-(2-1)-D-fructan fructohydrolase activity" EXACT [EC:3.2.1.153] - synonym: "beta-(2-1)fructan exohydrolase activity" EXACT [EC:3.2.1.153] + synonym: "beta-(2,1)-fructan exohydrolase activity" EXACT [EC:3.2.1.153] + synonym: "beta-(2,1)-linkage-specific fructan-beta-fructosidase activity" EXACT [EC:3.2.1.153] GO:0033949 : fructan beta-(2,6)-fructosidase activity - def: Catalysis of the hydrolysis of terminal, non-reducing 2,6-linked beta-D-fructofuranose residues in fructans. + def: Catalysis of the hydrolysis of terminal, non-reducing (2->6) linked beta-D-fructofuranose residues in fructans. - synonym: "beta-(2-6)-fructan exohydrolase activity" EXACT [EC:3.2.1.154] + synonym: "beta-(2,6)-fructan exohydrolase activity" EXACT [EC:3.2.1.154] GO:0033989 : 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity - xref: Reactome:REACT_110153 "25(S) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA, Mycobacterium tuberculosis" - xref: Reactome:REACT_89457 "25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA, Mycobacterium tuberculosis" GO:0033994 : glucuronan lyase activity - def: Catalysis of the reaction: (1,4)-beta-D-glucuronan = an oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl end + (1,4)-beta-D-glucuronan. This reaction is the eliminative cleavage of (1->4)-beta-D-glucuronans to give oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl groups at their non-reducing ends. Complete degradation of glucuronans results in the formation of tetrasaccharides. + def: Catalysis of the reaction: (1->4)-beta-D-glucuronan = an oligosaccharide with 4-deoxy-beta-D-gluc-4-enuronosyl end + (1->4)-beta-D-glucuronan. This reaction is the eliminative cleavage of (1->4)-beta-D-glucuronans to give oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl groups at their non-reducing ends. Complete degradation of glucuronans results in the formation of tetrasaccharides. GO:0034007 : S-linalool synthase activity - synonym: "Lis" RELATED [EC:4.2.3.25] GO:0034038 : deoxyhypusine synthase activity - xref: Reactome:REACT_88614 "EIF5A(Dhp) + 1,3-diaminopropane <=> EIF5A + spermidine, Plasmodium falciparum" - xref: Reactome:REACT_33278 "EIF5A + spermidine <=> EIF5A(Dhp) + 1,3-diaminopropane, Plasmodium falciparum" + xref: Reactome:REACT_115046 "EIF5A + spermidine <=> EIF5A(Dhp) + 1,3-diaminopropane, Caenorhabditis elegans" + xref: Reactome:REACT_113251 "EIF5A(Dhp) + 1,3-diaminopropane <=> EIF5A + spermidine, Caenorhabditis elegans" GO:0034130 : toll-like receptor 1 signaling pathway - xref: Reactome:REACT_8005 "Toll Like Receptor TLR1:TLR2 Cascade, Chlamydia trachomatis" + xref: Reactome:REACT_8005 "Toll Like Receptor TLR1:TLR2 Cascade, Homo sapiens" GO:0034134 : toll-like receptor 2 signaling pathway - xref: Reactome:REACT_92918 "Toll Like Receptor 2 Cascade, Arabidopsis thaliana" - xref: Reactome:REACT_97650 "Toll Like Receptor 2 Cascade, Sus scrofa" - xref: Reactome:REACT_65361 "Toll Like Receptor 2 Cascade, Gallus gallus" - xref: Reactome:REACT_110359 "Toll Like Receptor 2 Cascade, Danio rerio" - xref: Reactome:REACT_81077 "Toll Like Receptor 2 Cascade, Canis familiaris" - xref: Reactome:REACT_29705 "Toll Like Receptor 2 Cascade, Oryza sativa" - xref: Reactome:REACT_30806 "Toll Like Receptor 2 Cascade, Taeniopygia guttata" - xref: Reactome:REACT_94528 "Toll Like Receptor 2 Cascade, Caenorhabditis elegans" - xref: Reactome:REACT_92534 "Toll Like Receptor 2 Cascade, Rattus norvegicus" - xref: Reactome:REACT_7980 "Toll Like Receptor 2 Cascade, Homo sapiens" - xref: Reactome:REACT_98284 "Toll Like Receptor 2 Cascade, Schizosaccharomyces pombe" - xref: Reactome:REACT_101124 "Toll Like Receptor 2 Cascade, Dictyostelium discoideum" - xref: Reactome:REACT_32312 "Toll Like Receptor 2 Cascade, Saccharomyces cerevisiae" - xref: Reactome:REACT_31781 "Toll Like Receptor 2 Cascade, Bos taurus" - xref: Reactome:REACT_91964 "Toll Like Receptor 2 Cascade, Mus musculus" - xref: Reactome:REACT_109921 "Toll Like Receptor 2 Cascade, Xenopus tropicalis" - xref: Reactome:REACT_109018 "Toll Like Receptor 2 Cascade, Drosophila melanogaster" + xref: Reactome:REACT_31781 "Toll Like Receptor 2 (TLR2) Cascade, Bos taurus" + xref: Reactome:REACT_29705 "Toll Like Receptor 2 (TLR2) Cascade, Oryza sativa" + xref: Reactome:REACT_101124 "Toll Like Receptor 2 (TLR2) Cascade, Dictyostelium discoideum" + xref: Reactome:REACT_7980 "Toll Like Receptor 2 (TLR2) Cascade, Homo sapiens" + xref: Reactome:REACT_109921 "Toll Like Receptor 2 (TLR2) Cascade, Xenopus tropicalis" + xref: Reactome:REACT_65361 "Toll Like Receptor 2 (TLR2) Cascade, Gallus gallus" + xref: Reactome:REACT_109018 "Toll Like Receptor 2 (TLR2) Cascade, Drosophila melanogaster" + xref: Reactome:REACT_30806 "Toll Like Receptor 2 (TLR2) Cascade, Taeniopygia guttata" + xref: Reactome:REACT_97650 "Toll Like Receptor 2 (TLR2) Cascade, Sus scrofa" + xref: Reactome:REACT_94528 "Toll Like Receptor 2 (TLR2) Cascade, Caenorhabditis elegans" + xref: Reactome:REACT_98284 "Toll Like Receptor 2 (TLR2) Cascade, Schizosaccharomyces pombe" + xref: Reactome:REACT_32312 "Toll Like Receptor 2 (TLR2) Cascade, Saccharomyces cerevisiae" + xref: Reactome:REACT_81077 "Toll Like Receptor 2 (TLR2) Cascade, Canis familiaris" + xref: Reactome:REACT_92918 "Toll Like Receptor 2 (TLR2) Cascade, Arabidopsis thaliana" + xref: Reactome:REACT_92534 "Toll Like Receptor 2 (TLR2) Cascade, Rattus norvegicus" + xref: Reactome:REACT_110359 "Toll Like Receptor 2 (TLR2) Cascade, Danio rerio" + xref: Reactome:REACT_91964 "Toll Like Receptor 2 (TLR2) Cascade, Mus musculus" GO:0034188 : apolipoprotein A-I receptor activity - is_a: GO:0034186 + relationship: has_part GO:0034186 GO:0034199 : activation of protein kinase A activity - xref: Reactome:REACT_103211 "PKA activation, Caenorhabditis elegans" + xref: Reactome:REACT_92035 "PKA activation, Caenorhabditis elegans" + xref: Reactome:REACT_111951 "PKA activation, Plasmodium falciparum" GO:0034220 : ion transmembrane transport - xref: Reactome:REACT_99181 "Ion channel transport, Dictyostelium discoideum" - xref: Reactome:REACT_84760 "Ion transport by P-type ATPases, Schizosaccharomyces pombe" - xref: Reactome:REACT_105437 "Ion channel transport, Saccharomyces cerevisiae" - xref: Reactome:REACT_96459 "Ion transport by P-type ATPases, Saccharomyces cerevisiae" - xref: Reactome:REACT_95760 "Ion channel transport, Schizosaccharomyces pombe" - xref: Reactome:REACT_28150 "Ion transport by P-type ATPases, Dictyostelium discoideum" GO:0034329 : cell junction assembly - xref: Reactome:REACT_33407 "Cell junction organization, Dictyostelium discoideum" GO:0034332 : adherens junction organization - xref: Reactome:REACT_31798 "Adherens junctions interactions, Sus scrofa" + xref: Reactome:REACT_108185 "Adherens junctions interactions, Sus scrofa" + xref: Reactome:REACT_115366 "Adherens junctions interactions, Drosophila melanogaster" GO:0034348 : type III interferon receptor activity - is_a: GO:0034347 + relationship: has_part GO:0034347 GO:0034407 : cell wall (1->3)-beta-D-glucan metabolic process - name: cell wall 1,3-beta-D-glucan metabolic process + name: cell wall (1->3)-beta-D-glucan metabolic process - def: The chemical reactions and pathways involving beta-1,3 glucans, compounds composed of glucose residues linked by 1,3-beta-D-glucosidic bonds, found in the walls of cells. + def: The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells. + synonym: "cell wall 1,3-beta-D-glucan metabolic process" EXACT [] GO:0034409 : ascospore wall (1->3)-beta-D-glucan metabolic process - name: ascospore wall 1,3-beta-D-glucan metabolic process + name: ascospore wall (1->3)-beta-D-glucan metabolic process - def: The chemical reactions and pathways involving beta-1,3 glucans, compounds composed of glucose residues linked by 1,3-beta-D-glucosidic bonds, found in the walls of ascospores. + def: The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores. + synonym: "ascospore wall 1,3-beta-D-glucan metabolic process" EXACT [] GO:0034411 : cell wall (1->3)-beta-D-glucan biosynthetic process - name: cell wall 1,3-beta-D-glucan biosynthetic process + name: cell wall (1->3)-beta-D-glucan biosynthetic process - def: The chemical reactions and pathways resulting in the formation of 1,3-beta-glucans, compounds composed of glucose residues linked by 1,3-beta-D-glucosidic bonds, found in the walls of cells. + def: The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells. + synonym: "cell wall 1,3-beta-D-glucan biosynthetic process" BROAD [] GO:0034413 : ascospore wall (1->3)-beta-D-glucan biosynthetic process - name: ascospore wall 1,3-beta-D-glucan biosynthetic process + name: ascospore wall (1->3)-beta-D-glucan biosynthetic process - def: The chemical reactions and pathways resulting in the formation of 1,3-beta-glucans, compounds composed of glucose residues linked by 1,3-beta-D-glucosidic bonds, found in the walls of ascospores. + def: The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores. + synonym: "ascospore wall 1,3-beta-D-glucan biosynthetic process" BROAD [] GO:0034520 : 2-naphthaldehyde dehydrogenase activity - is_a: GO:0016620 + is_a: GO:0004029 GO:0034530 : 4-hydroxymethylsalicyaldehyde dehydrogenase activity - is_a: GO:0016620 + is_a: GO:0004029 GO:0034593 : phosphatidylinositol bisphosphate phosphatase activity - is_a: GO:0004437 + is_a: GO:0016791 GO:0034594 : phosphatidylinositol trisphosphate phosphatase activity - is_a: GO:0004437 + is_a: GO:0016791 GO:0034595 : phosphatidylinositol phosphate 5-phosphatase activity - is_a: GO:0004437 + is_a: GO:0016791 GO:0034596 : phosphatidylinositol phosphate 4-phosphatase activity - is_a: GO:0004437 + is_a: GO:0016791 GO:0034602 : oxoglutarate dehydrogenase (NAD+) activity - xref: Reactome:REACT_79126 "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+, Saccharomyces cerevisiae" + xref: Reactome:REACT_30875 "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+, Saccharomyces cerevisiae" + xref: Reactome:REACT_115419 "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+, Arabidopsis thaliana" + xref: Reactome:REACT_113722 "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+, Oryza sativa" + xref: Reactome:REACT_115335 "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+, Escherichia coli" + xref: Reactome:REACT_114766 "alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+, Oryza sativa" + xref: Reactome:REACT_112439 "alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+, Escherichia coli" + xref: Reactome:REACT_115236 "alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+, Arabidopsis thaliana" GO:0034641 : cellular nitrogen compound metabolic process - xref: Reactome:REACT_102044 "Metabolism of amino acids and derivatives, Sus scrofa" + xref: Reactome:REACT_109042 "Metabolism of amino acids and derivatives, Sus scrofa" GO:0035004 : phosphatidylinositol 3-kinase activity + xref: Reactome:REACT_111081 "Synthesis of PIP3 from PIP2 by PI3K, Homo sapiens" GO:0035005 : 1-phosphatidylinositol-4-phosphate 3-kinase activity - name: phosphatidylinositol-4-phosphate 3-kinase activity + name: 1-phosphatidylinositol-4-phosphate 3-kinase activity + synonym: "phosphatidylinositol-4-phosphate 3-kinase activity" EXACT [] GO:0035299 : inositol pentakisphosphate 2-kinase activity - is_a: GO:0004428 + is_a: GO:0016301 GO:0035338 : long-chain fatty-acyl-CoA biosynthetic process + xref: Reactome:REACT_112257 "Synthesis of very long-chain fatty acyl-CoAs, Dictyostelium discoideum" + xref: Reactome:REACT_112844 "Synthesis of very long-chain fatty acyl-CoAs, Plasmodium falciparum" + xref: Reactome:REACT_113523 "Synthesis of very long-chain fatty acyl-CoAs, Mycobacterium tuberculosis" GO:0035643 : L-DOPA receptor activity - is_a: GO:0072544 + relationship: has_part GO:0072544 GO:0035666 : TRIF-dependent toll-like receptor signaling pathway + xref: Reactome:REACT_111135 "TRIF mediated TLR3 signaling, Homo sapiens" + xref: Reactome:REACT_111936 "TRIF mediated TLR3 signaling, Schizosaccharomyces pombe" + xref: Reactome:REACT_112079 "TRIF mediated TLR3 signaling, Caenorhabditis elegans" + xref: Reactome:REACT_112508 "TRIF mediated TLR3 signaling, Taeniopygia guttata" + xref: Reactome:REACT_112658 "TRIF mediated TLR3 signaling, Xenopus tropicalis" + xref: Reactome:REACT_112958 "TRIF mediated TLR3 signaling, Danio rerio" + xref: Reactome:REACT_113472 "TRIF mediated TLR3 signaling, Sus scrofa" + xref: Reactome:REACT_113475 "TRIF mediated TLR3 signaling, Oryza sativa" + xref: Reactome:REACT_113731 "TRIF mediated TLR3 signaling, Gallus gallus" + xref: Reactome:REACT_113758 "TRIF mediated TLR3 signaling, Dictyostelium discoideum" + xref: Reactome:REACT_114089 "TRIF mediated TLR3 signaling, Canis familiaris" + xref: Reactome:REACT_114251 "TRIF mediated TLR3 signaling, Saccharomyces cerevisiae" + xref: Reactome:REACT_114313 "TRIF mediated TLR3 signaling, Drosophila melanogaster" + xref: Reactome:REACT_114629 "TRIF mediated TLR3 signaling, Mus musculus" + xref: Reactome:REACT_114730 "TRIF mediated TLR3 signaling, Bos taurus" + xref: Reactome:REACT_115269 "TRIF mediated TLR3 signaling, Rattus norvegicus" + xref: Reactome:REACT_115453 "TRIF mediated TLR3 signaling, Arabidopsis thaliana" GO:0035738 : envenomation - def: The process by which venom is forced into an organism by the bite or sting of another organism. + def: The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the manifestation of damage to the bitten organism. GO:0035821 : modification of morphology or physiology of other organism - is_a: GO:0044419 + is_a: GO:0051704 GO:0035872 : nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway + xref: Reactome:REACT_102126 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Xenopus tropicalis" + xref: Reactome:REACT_105549 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Gallus gallus" + xref: Reactome:REACT_109121 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Mus musculus" + xref: Reactome:REACT_112945 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Drosophila melanogaster" + xref: Reactome:REACT_75913 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Homo sapiens" + xref: Reactome:REACT_85368 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Rattus norvegicus" + xref: Reactome:REACT_91372 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Danio rerio" + xref: Reactome:REACT_95496 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Bos taurus" + xref: Reactome:REACT_95597 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Taeniopygia guttata" + xref: Reactome:REACT_97582 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Canis familiaris" + xref: Reactome:REACT_99740 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Sus scrofa" GO:0035892 : modulation of platelet aggregation in other organism + is_a: GO:0044364 GO:0035916 : modulation of calcium channel activity in other organism - is_a: GO:0035821 + is_a: GO:0044359 GO:0035917 : negative regulation of calcium channel activity in other organism + is_a: GO:0044362 + is_a: GO:0052204 GO:0042008 : interleukin-18 receptor activity - is_a: GO:0042007 + relationship: has_part GO:0042007 GO:0042010 : interleukin-15 receptor activity - is_a: GO:0042009 + relationship: has_part GO:0042009 GO:0042012 : interleukin-16 receptor activity - is_a: GO:0042011 + relationship: has_part GO:0042011 GO:0042014 : interleukin-19 receptor activity - is_a: GO:0042013 + relationship: has_part GO:0042013 GO:0042016 : interleukin-20 receptor activity - is_a: GO:0042015 + relationship: has_part GO:0042015 GO:0042018 : interleukin-22 receptor activity - is_a: GO:0042017 + relationship: has_part GO:0042017 GO:0042020 : interleukin-23 receptor activity - is_a: GO:0042019 + relationship: has_part GO:0042019 GO:0042124 : 1,3-beta-glucanosyltransferase activity - def: Catalysis of the splitting and linkage of 1,3-beta-glucan molecules, resulting in 1,3-beta-glucan chain elongation. + def: Catalysis of the splitting and linkage of (1->3)-beta-D-glucan molecules, resulting in (1->3)-beta-D-glucan chain elongation. GO:0042132 : fructose 1,6-bisphosphate 1-phosphatase activity + xref: Reactome:REACT_113175 "D-fructose 1,6-bisphosphate + H2O => D-fructose 6-phosphate + orthophosphate, Escherichia coli" GO:0042133 : neurotransmitter metabolic process + xref: Reactome:REACT_115498 "Metabolism of Noradrenaline, Dictyostelium discoideum" GO:0042136 : neurotransmitter biosynthetic process - xref: Reactome:REACT_88812 "Neurotransmitter Clearance In The Synaptic Cleft, Saccharomyces cerevisiae" - xref: Reactome:REACT_86523 "Neurotransmitter Clearance In The Synaptic Cleft, Schizosaccharomyces pombe" + xref: Reactome:REACT_107523 "Neurotransmitter Clearance In The Synaptic Cleft, Schizosaccharomyces pombe" + xref: Reactome:REACT_112396 "Neurotransmitter Clearance In The Synaptic Cleft, Escherichia coli" + xref: Reactome:REACT_115066 "Neurotransmitter Clearance In The Synaptic Cleft, Dictyostelium discoideum" GO:0042148 : strand invasion - xref: Reactome:REACT_972 "Strand invasion, Homo sapiens" GO:0042157 : lipoprotein metabolic process + xref: Reactome:REACT_112911 "apolipoprotein(a) + LDL => Lp(a), Xenopus tropicalis" GO:0042167 : heme catabolic process + xref: Reactome:REACT_114440 "Heme degradation, Caenorhabditis elegans" GO:0042197 : halogenated hydrocarbon metabolic process - xref: Reactome:REACT_97585 "Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide, Xenopus tropicalis" GO:0042304 : regulation of fatty acid biosynthetic process + xref: Reactome:REACT_112072 "AMPK inhibits chREBP transcriptional activation activity, Danio rerio" GO:0042359 : vitamin D metabolic process - xref: Reactome:REACT_101026 "Vitamin D (calciferol) metabolism, Caenorhabditis elegans" GO:0042392 : sphingosine-1-phosphate phosphatase activity - xref: Reactome:REACT_82438 "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - PPAP], Drosophila melanogaster" - xref: Reactome:REACT_33509 "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [extracellular], Drosophila melanogaster" + xref: Reactome:REACT_114519 "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - SGPP], Saccharomyces cerevisiae" + xref: Reactome:REACT_113452 "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - SGPP], Schizosaccharomyces pombe" GO:0042446 : hormone biosynthetic process - xref: Reactome:REACT_102442 "Biosynthesis of amine and peptide hormones, Sus scrofa" - xref: Reactome:REACT_104251 "Biosynthesis of amine and peptide hormones, Arabidopsis thaliana" - xref: Reactome:REACT_105476 "Biosynthesis of amine and peptide hormones, Rattus norvegicus" - xref: Reactome:REACT_107945 "Biosynthesis of amine and peptide hormones, Drosophila melanogaster" - xref: Reactome:REACT_110983 "Biosynthesis of amine and peptide hormones, Canis familiaris" - xref: Reactome:REACT_15314 "Biosynthesis of amine and peptide hormones, Homo sapiens" - xref: Reactome:REACT_32056 "Biosynthesis of amine and peptide hormones, Staphylococcus aureus N315" - xref: Reactome:REACT_33912 "Biosynthesis of amine and peptide hormones, Gallus gallus" - xref: Reactome:REACT_80318 "Biosynthesis of amine and peptide hormones, Danio rerio" - xref: Reactome:REACT_85276 "Biosynthesis of amine and peptide hormones, Bos taurus" - xref: Reactome:REACT_85503 "Biosynthesis of amine and peptide hormones, Taeniopygia guttata" - xref: Reactome:REACT_86029 "Biosynthesis of amine and peptide hormones, Mycobacterium tuberculosis" - xref: Reactome:REACT_87059 "Biosynthesis of amine and peptide hormones, Dictyostelium discoideum" - xref: Reactome:REACT_88717 "Biosynthesis of amine and peptide hormones, Mus musculus" - xref: Reactome:REACT_91733 "Biosynthesis of amine and peptide hormones, Xenopus tropicalis" - xref: Reactome:REACT_92236 "Biosynthesis of amine and peptide hormones, Caenorhabditis elegans" - xref: Reactome:REACT_99547 "Biosynthesis of amine and peptide hormones, Oryza sativa" GO:0042590 : antigen processing and presentation of exogenous peptide antigen via MHC class I + xref: Reactome:REACT_111119 "Antigen processing-Cross presentation, Homo sapiens" GO:0042626 : ATPase activity, coupled to transmembrane movement of substances - xref: Reactome:REACT_81764 "LTC4 is exported from the cell, Schizosaccharomyces pombe" - xref: Reactome:REACT_94905 "LTC4 is exported from the cell, Canis familiaris" - xref: Reactome:REACT_29118 "LTC4 is exported from the cell, Mus musculus" - xref: Reactome:REACT_91861 "LTC4 is exported from the cell, Bos taurus" - xref: Reactome:REACT_104723 "LTC4 is exported from the cell, Sus scrofa" - xref: Reactome:REACT_29646 "LTC4 is exported from the cell, Taeniopygia guttata" - xref: Reactome:REACT_78784 "LTC4 is exported from the cell, Saccharomyces cerevisiae" - xref: Reactome:REACT_31426 "LTC4 is exported from the cell, Rattus norvegicus" - xref: Reactome:REACT_81345 "LTC4 is exported from the cell, Gallus gallus" - xref: Reactome:REACT_87167 "LTC4 is exported from the cell, Dictyostelium discoideum" - xref: Reactome:REACT_101912 "LTC4 is exported from the cell, Danio rerio" - xref: Reactome:REACT_15474 "LTC4 is exported from the cell, Homo sapiens" - xref: Reactome:REACT_103276 "LTC4 is exported from the cell, Drosophila melanogaster" - xref: Reactome:REACT_108270 "LTC4 is exported from the cell, Oryza sativa" - xref: Reactome:REACT_102827 "LTC4 is exported from the cell, Caenorhabditis elegans" - xref: Reactome:REACT_81117 "LTC4 is exported from the cell, Arabidopsis thaliana" - xref: Reactome:REACT_30914 "LTC4 is exported from the cell, Xenopus tropicalis" + xref: Reactome:REACT_111189 "ABCA4 mediates retinal transport, Homo sapiens" + xref: Reactome:REACT_15474 "ABCC1 mediates LTC4 export from the cell, Homo sapiens" GO:0042654 : ecdysis-triggering hormone receptor activity - is_a: GO:0042562 + relationship: has_part GO:0042562 GO:0042692 : muscle cell differentiation + xref: Reactome:REACT_113484 "Myogenesis, Caenorhabditis elegans" GO:0042730 : fibrinolysis - xref: Reactome:REACT_29927 "Dissolution of Fibrin Clot, Caenorhabditis elegans" GO:0042776 : mitochondrial ATP synthesis coupled proton transport - xref: Reactome:REACT_102259 "Enzyme-bound ATP is released, Taeniopygia guttata" - xref: Reactome:REACT_76939 "Formation of ATP by chemiosmotic coupling, Taeniopygia guttata" GO:0042781 : 3'-tRNA processing endoribonuclease activity - synonym: "tRNase Z" RELATED [EC:3.1.26.11] GO:0042787 : protein ubiquitination involved in ubiquitin-dependent protein catabolic process - xref: Reactome:REACT_101051 "Multiubiquitination of APC/C-associated Cdh1, Arabidopsis thaliana" - xref: Reactome:REACT_101618 "Ubiquitination of Cyclin A by APC/C:Cdc20 complex, Arabidopsis thaliana" - xref: Reactome:REACT_107859 "Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex, Arabidopsis thaliana" - xref: Reactome:REACT_34698 "Ubiquitination of Securin by phospho-APC/C:Cdc20 complex, Arabidopsis thaliana" + xref: Reactome:REACT_114376 "Ubiquitination of Cyclin A by APC/C:Cdc20 complex, Oryza sativa" GO:0042972 : licheninase activity - def: Catalysis of the hydrolysis of 1,4-beta-D-glucosidic linkages in beta-D-glucans containing 1,3- and 1,4-bonds. + def: Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3) and (1->4) bonds. GO:0042973 : glucan endo-1,3-beta-D-glucosidase activity - def: Catalysis of the hydrolysis of 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans. + def: Catalysis of the hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans. GO:0042981 : regulation of apoptosis - xref: Reactome:REACT_91144 "Regulation of Apoptosis, Schizosaccharomyces pombe" - xref: Reactome:REACT_103151 "Regulation of Apoptosis, Saccharomyces cerevisiae" - xref: Reactome:REACT_95902 "Regulation of Apoptosis, Dictyostelium discoideum" GO:0043097 : pyrimidine nucleoside salvage - xref: Reactome:REACT_92837 "Pyrimidine salvage reactions, Sus scrofa" + xref: Reactome:REACT_101113 "Pyrimidine salvage reactions, Sus scrofa" GO:0043101 : purine-containing compound salvage - xref: Reactome:REACT_103029 "Purine salvage, Sus scrofa" + xref: Reactome:REACT_88584 "Purine salvage, Sus scrofa" GO:0043123 : positive regulation of I-kappaB kinase/NF-kappaB cascade - xref: Reactome:REACT_24918 "IRAK1 recruits IKK comlex, Homo sapiens" + xref: Reactome:REACT_24918 "IRAK1 recruits IKK complex, Homo sapiens" GO:0043161 : proteasomal ubiquitin-dependent protein catabolic process - xref: Reactome:REACT_32577 "Degradation multiubiquitinated Cyclin A, Taeniopygia guttata" GO:0043225 : anion transmembrane-transporting ATPase activity + xref: Reactome:REACT_111162 "The ABCC family mediates organic anion transport, Homo sapiens" GO:0043252 : sodium-independent organic anion transport - xref: Reactome:REACT_34045 "Transport of organic anions, Gallus gallus" + xref: Reactome:REACT_113843 "Transport of organic anions, Danio rerio" GO:0043404 : corticotropin-releasing hormone receptor activity - is_a: GO:0051424 + relationship: has_part GO:0051424 GO:0043441 : acetoacetic acid biosynthetic process - xref: Reactome:REACT_102599 "Formation of Acetoacetic Acid, Mycobacterium tuberculosis" - xref: Reactome:REACT_103100 "Formation of Acetoacetic Acid, Mus musculus" - xref: Reactome:REACT_103442 "Formation of Acetoacetic Acid, Canis familiaris" - xref: Reactome:REACT_103949 "Formation of Acetoacetic Acid, Gallus gallus" - xref: Reactome:REACT_105058 "Formation of Acetoacetic Acid, Danio rerio" - xref: Reactome:REACT_105676 "Formation of Acetoacetic Acid, Plasmodium falciparum" - xref: Reactome:REACT_110249 "Formation of Acetoacetic Acid, Taeniopygia guttata" - xref: Reactome:REACT_1733 "Formation of Acetoacetic Acid, Homo sapiens" - xref: Reactome:REACT_28148 "Formation of Acetoacetic Acid, Xenopus tropicalis" - xref: Reactome:REACT_30761 "Formation of Acetoacetic Acid, Schizosaccharomyces pombe" - xref: Reactome:REACT_80115 "Formation of Acetoacetic Acid, Oryza sativa" - xref: Reactome:REACT_80443 "Formation of Acetoacetic Acid, Rattus norvegicus" - xref: Reactome:REACT_80856 "Formation of Acetoacetic Acid, Bos taurus" - xref: Reactome:REACT_85987 "Formation of Acetoacetic Acid, Caenorhabditis elegans" - xref: Reactome:REACT_86901 "Formation of Acetoacetic Acid, Sus scrofa" - xref: Reactome:REACT_87123 "Formation of Acetoacetic Acid, Staphylococcus aureus N315" - xref: Reactome:REACT_87774 "Formation of Acetoacetic Acid, Drosophila melanogaster" - xref: Reactome:REACT_94761 "Formation of Acetoacetic Acid, Arabidopsis thaliana" - xref: Reactome:REACT_94961 "Formation of Acetoacetic Acid, Saccharomyces cerevisiae" - xref: Reactome:REACT_95940 "Formation of Acetoacetic Acid, Dictyostelium discoideum" GO:0043687 : post-translational protein modification - xref: Reactome:REACT_89099 "Post-translational modification: gamma carboxylation and hypusine formation, Plasmodium falciparum" + xref: Reactome:REACT_113592 "Post-translational modification: gamma carboxylation and hypusine formation, Caenorhabditis elegans" GO:0043733 : DNA-3-methylbase glycosylase activity - name: DNA-3-methyladenine glycosylase III activity + name: DNA-3-methylbase glycosylase activity - def: Catalysis of the hydrolysis of alkylated DNA; recognizes and removes alkylated 3-methylpurines and pyrimidines by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic or apyrimidinic (AP) site. + def: Catalysis of the reaction: DNA containing 3-methylbase + H2O = DNA with abasic site + 3-methylbase. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylpurine or 3-methylpyrimidine base and the deoxyribose sugar to remove the methylated base, leaving an apurinic or apyrimidinic site. + synonym: "DNA-3-methyladenine glycosylase III" RELATED [] GO:0043734 : DNA-N1-methyladenine dioxygenase activity - synonym: "alkB" NARROW [] GO:0043744 : N2-acetyl-L-aminoadipate kinase activity + alt_id: GO:0043868 - def: Catalysis of the reaction: N2-acetyl-L-aminoadipate + ATP = N2-acetyl-L-aminoadipyl-delta-phosphate + ADP. + def: Catalysis of the reaction: ATP + N-acetyl-L-aminoadipate = ADP + N-acetyl-L-aminoadipate 5-phosphate. + synonym: "LysZ" RELATED [] + synonym: "N-acetyl-L-aminoadipate 5-phosphotransferase activity" EXACT [] + synonym: "N-acetylaminoadipate kinase activity" EXACT [] + synonym: "acetylaminoadipate kinase activity" EXACT [] GO:0043896 : glucan 1,6-alpha-glucosidase activity - def: Catalysis of the hydrolysis of 1,6-alpha-D-glucosidic linkages in 1,6-alpha-D-glucans and derived oligosaccharides. + def: Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in (1->6)-alpha-D-glucans and derived oligosaccharides. GO:0043916 : DNA-7-methylguanine glycosylase activity - def: Catalysis of the hydrolysis of alkylated DNA; recognizes and removes the alkylated base 7-methylguanine. + def: Catalysis of the reaction: DNA containing 7-methylguanine + H2O = DNA with abasic site + 7-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methylguanine and the deoxyribose sugar to remove the 7-methylguanine, leaving an abasic site. - xref: EC:3.2.2.- + xref: EC:3.2.2.21 + xref: MetaCyc:3.2.2.21-RXN GO:0043928 : exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay - xref: Reactome:REACT_101018 "mRNA Decay by 5' to 3' Exoribonuclease, Caenorhabditis elegans" - xref: Reactome:REACT_99503 "mRNA Decay by 3' to 5' Exoribonuclease, Schizosaccharomyces pombe" - xref: Reactome:REACT_100454 "mRNA Decay by 5' to 3' Exoribonuclease, Rattus norvegicus" + xref: Reactome:REACT_30153 "mRNA Decay by 3' to 5' Exoribonuclease, Schizosaccharomyces pombe" + xref: Reactome:REACT_34492 "mRNA Decay by 5' to 3' Exoribonuclease, Caenorhabditis elegans" GO:0044245 : polysaccharide digestion + xref: Reactome:REACT_114891 "Digestion of dietary carbohydrate, Escherichia coli" GO:0044255 : cellular lipid metabolic process - xref: Reactome:REACT_104402 "Fatty acid, triacylglycerol, and ketone body metabolism, Dictyostelium discoideum" - xref: Reactome:REACT_94266 "Fatty acid, triacylglycerol, and ketone body metabolism, Sus scrofa" + xref: Reactome:REACT_83359 "Fatty acid, triacylglycerol, and ketone body metabolism, Sus scrofa" + xref: Reactome:REACT_112736 "Peroxisomal lipid metabolism, Plasmodium falciparum" + xref: Reactome:REACT_89268 "Fatty acid, triacylglycerol, and ketone body metabolism, Dictyostelium discoideum" GO:0044257 : cellular protein catabolic process - xref: Reactome:REACT_103470 "Degradation of newly synthesized ApoB-48, Bos taurus" + xref: Reactome:REACT_86672 "Degradation of newly synthesized ApoB-48, Bos taurus" GO:0044267 : cellular protein metabolic process - xref: Reactome:REACT_98814 "Metabolism of proteins, Sus scrofa" + xref: Reactome:REACT_81994 "Metabolism of proteins, Sus scrofa" GO:0044281 : small molecule metabolic process + xref: Reactome:REACT_111217 "Metabolism, Homo sapiens" + xref: Reactome:REACT_112077 "Metabolism, Xenopus tropicalis" + xref: Reactome:REACT_112140 "Metabolism, Dictyostelium discoideum" + xref: Reactome:REACT_112621 "Metabolism, Mus musculus" + xref: Reactome:REACT_112912 "Metabolism, Arabidopsis thaliana" + xref: Reactome:REACT_113131 "Metabolism, Schizosaccharomyces pombe" + xref: Reactome:REACT_113305 "Metabolism, Canis familiaris" + xref: Reactome:REACT_113457 "Metabolism, Mycobacterium tuberculosis" + xref: Reactome:REACT_113568 "Metabolism, Rattus norvegicus" + xref: Reactome:REACT_113610 "Metabolism, Caenorhabditis elegans" + xref: Reactome:REACT_113934 "Metabolism, Escherichia coli" + xref: Reactome:REACT_114081 "Metabolism, Gallus gallus" + xref: Reactome:REACT_114137 "Metabolism, Sus scrofa" + xref: Reactome:REACT_114421 "Metabolism, Saccharomyces cerevisiae" + xref: Reactome:REACT_114473 "Metabolism, Danio rerio" + xref: Reactome:REACT_114495 "Metabolism, Staphylococcus aureus N315" + xref: Reactome:REACT_114668 "Metabolism, Plasmodium falciparum" + xref: Reactome:REACT_114983 "Metabolism, Drosophila melanogaster" + xref: Reactome:REACT_115063 "Metabolism, Taeniopygia guttata" + xref: Reactome:REACT_115388 "Metabolism, Oryza sativa" + xref: Reactome:REACT_115420 "Metabolism, Bos taurus" GO:0044284 : mitochondrial crista junction - name: crista junction + name: mitochondrial crista junction - def: Tubular structures of relatively uniform size that connect mitochondrial cristae to the inner mitchondrial membrane. + def: A tubular structure of relatively uniform size that connects a mitochondrial crista to the mitochondrial inner boundary membrane. + synonym: "crista junction" EXACT [] + synonym: "cristae junction" EXACT [] + relationship: part_of GO:0005743 GO:0045007 : depurination - xref: Reactome:REACT_107234 "Recognition and association of DNA glycosylase with site containing an affected purine, Schizosaccharomyces pombe" + xref: Reactome:REACT_99935 "Recognition and association of DNA glycosylase with site containing an affected purine, Schizosaccharomyces pombe" GO:0045087 : innate immune response - xref: Reactome:REACT_81815 "Innate Immunity Signaling, Saccharomyces cerevisiae" - xref: Reactome:REACT_31297 "Innate Immunity Signaling, Xenopus tropicalis" - xref: Reactome:REACT_90618 "Innate Immunity Signaling, Caenorhabditis elegans" - xref: Reactome:REACT_110518 "Innate Immunity Signaling, Taeniopygia guttata" - xref: Reactome:REACT_95642 "Innate Immunity Signaling, Oryza sativa" - xref: Reactome:REACT_99610 "Innate Immunity Signaling, Danio rerio" - xref: Reactome:REACT_78575 "Innate Immunity Signaling, Canis familiaris" - xref: Reactome:REACT_81962 "Innate Immunity Signaling, Dictyostelium discoideum" - xref: Reactome:REACT_94451 "Innate Immunity Signaling, Rattus norvegicus" - xref: Reactome:REACT_108180 "Innate Immunity Signaling, Arabidopsis thaliana" - xref: Reactome:REACT_90753 "Innate Immunity Signaling, Schizosaccharomyces pombe" - xref: Reactome:REACT_32992 "Innate Immunity Signaling, Gallus gallus" - xref: Reactome:REACT_6802 "Innate Immunity Signaling, Homo sapiens" - xref: Reactome:REACT_95471 "Innate Immunity Signaling, Sus scrofa" - xref: Reactome:REACT_101086 "Innate Immunity Signaling, Bos taurus" - xref: Reactome:REACT_86987 "Innate Immunity Signaling, Mus musculus" - xref: Reactome:REACT_88681 "Innate Immunity Signaling, Drosophila melanogaster" + xref: Reactome:REACT_101086 "Innate Immune System, Bos taurus" + xref: Reactome:REACT_95471 "Innate Immune System, Sus scrofa" + xref: Reactome:REACT_81962 "Innate Immune System, Dictyostelium discoideum" + xref: Reactome:REACT_94451 "Innate Immune System, Rattus norvegicus" + xref: Reactome:REACT_90753 "Innate Immune System, Schizosaccharomyces pombe" + xref: Reactome:REACT_88681 "Innate Immune System, Drosophila melanogaster" + xref: Reactome:REACT_31297 "Innate Immune System, Xenopus tropicalis" + xref: Reactome:REACT_86987 "Innate Immune System, Mus musculus" + xref: Reactome:REACT_32992 "Innate Immune System, Gallus gallus" + xref: Reactome:REACT_108180 "Innate Immune System, Arabidopsis thaliana" + xref: Reactome:REACT_78575 "Innate Immune System, Canis familiaris" + xref: Reactome:REACT_110518 "Innate Immune System, Taeniopygia guttata" + xref: Reactome:REACT_6802 "Innate Immune System, Homo sapiens" + xref: Reactome:REACT_90618 "Innate Immune System, Caenorhabditis elegans" + xref: Reactome:REACT_99610 "Innate Immune System, Danio rerio" + xref: Reactome:REACT_81815 "Innate Immune System, Saccharomyces cerevisiae" + xref: Reactome:REACT_95642 "Innate Immune System, Oryza sativa" GO:0045153 : electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity + xref: Reactome:REACT_113728 "Electron transfer from ubiquinol to cytochrome c of complex III, Bos taurus" + xref: Reactome:REACT_112720 "Electron transfer from ubiquinol to cytochrome c of complex III, Canis familiaris" + xref: Reactome:REACT_113468 "Electron transfer from ubiquinol to cytochrome c of complex III, Rattus norvegicus" + xref: Reactome:REACT_115341 "Electron transfer from ubiquinol to cytochrome c of complex III, Sus scrofa" + xref: Reactome:REACT_112947 "Electron transfer from ubiquinol to cytochrome c of complex III, Drosophila melanogaster" GO:0045174 : glutathione dehydrogenase (ascorbate) activity - xref: Reactome:REACT_107653 "Reduction of dehydroascorbate to ascorbate, Caenorhabditis elegans" + xref: Reactome:REACT_114703 "Reduction of dehydroascorbate to ascorbate, Danio rerio" + xref: Reactome:REACT_114537 "Reduction of dehydroascorbate to ascorbate, Oryza sativa" + xref: Reactome:REACT_114041 "Reduction of dehydroascorbate to ascorbate, Arabidopsis thaliana" GO:0045216 : cell-cell junction organization + xref: Reactome:REACT_114636 "Cell-cell junction organization, Drosophila melanogaster" GO:0045329 : carnitine biosynthetic process - xref: Reactome:REACT_95542 "Carnitine synthesis, Sus scrofa" + xref: Reactome:REACT_91272 "Carnitine synthesis, Sus scrofa" + xref: Reactome:REACT_115191 "Carnitine synthesis, Staphylococcus aureus N315" + xref: Reactome:REACT_115020 "Carnitine synthesis, Mycobacterium tuberculosis" GO:0045506 : interleukin-24 receptor activity - is_a: GO:0045510 + relationship: has_part GO:0045510 GO:0045507 : interleukin-25 receptor activity - is_a: GO:0045511 + relationship: has_part GO:0045511 GO:0045508 : interleukin-26 receptor activity - is_a: GO:0045512 + relationship: has_part GO:0045512 GO:0045509 : interleukin-27 receptor activity - is_a: GO:0045513 + relationship: has_part GO:0045513 GO:0045786 : negative regulation of cell cycle + xref: Reactome:REACT_112803 "p75NTR negatively regulates cell cycle via SC1, Drosophila melanogaster" GO:0046134 : pyrimidine nucleoside biosynthetic process - xref: Reactome:REACT_29545 "Pyrimidine biosynthesis, Sus scrofa" + xref: Reactome:REACT_29226 "Pyrimidine biosynthesis, Sus scrofa" GO:0046135 : pyrimidine nucleoside catabolic process - xref: Reactome:REACT_77811 "Pyrimidine catabolism, Sus scrofa" + xref: Reactome:REACT_29523 "Pyrimidine catabolism, Sus scrofa" + xref: Reactome:REACT_113010 "Pyrimidine catabolism, Schizosaccharomyces pombe" GO:0046209 : nitric oxide metabolic process - xref: Reactome:REACT_79883 "Metabolism of nitric oxide, Escherichia coli" - xref: Reactome:REACT_86871 "Metabolism of nitric oxide, Dictyostelium discoideum" - xref: Reactome:REACT_31937 "Metabolism of nitric oxide, Drosophila melanogaster" - xref: Reactome:REACT_102514 "Metabolism of nitric oxide, Staphylococcus aureus N315" + xref: Reactome:REACT_114905 "Metabolism of nitric oxide, Taeniopygia guttata" GO:0046320 : regulation of fatty acid oxidation - xref: Reactome:REACT_102936 "Activated AMPK stimulates fatty-acid oxidation in muscle, Plasmodium falciparum" + xref: Reactome:REACT_114959 "Activated AMPK stimulates fatty-acid oxidation in muscle, Mycobacterium tuberculosis" GO:0046478 : lactosylceramide metabolic process - def: The chemical reactions and pathways involving lactosylceramides, Gal beta(1,4)Glc beta(1,1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides. + def: The chemical reactions and pathways involving lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides. GO:0046487 : glyoxylate metabolic process + xref: Reactome:REACT_115415 "Glyoxylate metabolism, Schizosaccharomyces pombe" + xref: Reactome:REACT_115484 "Glyoxylate metabolism, Mycobacterium tuberculosis" GO:0046557 : glucan endo-1,6-beta-glucosidase activity - def: Catalysis of the random hydrolysis of 1,6-linkages in 1,6-beta-D-glucans. + def: Catalysis of the random hydrolysis of (1->6) linkages in (1->6)-beta-D-glucans. GO:0046558 : arabinan endo-1,5-alpha-L-arabinosidase activity - def: Catalysis of the endohydrolysis of 1,5-alpha-arabinofuranosidic linkages in 1,5-arabinans. + def: Catalysis of the endohydrolysis of (1->5)-alpha-arabinofuranosidic linkages in (1->5) arabinans. - synonym: "endo-1,5-a-L-arabinanase activity" EXACT [] GO:0046592 : polyamine oxidase activity - xref: Reactome:REACT_78052 "Spermine is oxidized to spermidine, Saccharomyces cerevisiae" - xref: Reactome:REACT_86745 "N-acetylspermidine is oxidized to putrescine, Saccharomyces cerevisiae" - xref: Reactome:REACT_85463 "N-acetylspermine is oxidised to spermidine, Saccharomyces cerevisiae" + xref: Reactome:REACT_112199 "N-acetylspermidine is oxidized to putrescine, Drosophila melanogaster" + xref: Reactome:REACT_114114 "Spermine is oxidized to spermidine, Caenorhabditis elegans" + xref: Reactome:REACT_114621 "N-acetylspermidine is oxidized to putrescine, Caenorhabditis elegans" + xref: Reactome:REACT_112853 "N-acetylspermine is oxidised to spermidine, Drosophila melanogaster" + xref: Reactome:REACT_108826 "N-acetylspermine is oxidised to spermidine, Saccharomyces cerevisiae" + xref: Reactome:REACT_114150 "Spermine is oxidized to spermidine, Drosophila melanogaster" + xref: Reactome:REACT_78001 "N-acetylspermidine is oxidized to putrescine, Saccharomyces cerevisiae" + xref: Reactome:REACT_114231 "N-acetylspermine is oxidised to spermidine, Caenorhabditis elegans" + xref: Reactome:REACT_84703 "Spermine is oxidized to spermidine, Saccharomyces cerevisiae" GO:0046777 : protein autophosphorylation - xref: Reactome:REACT_80221 "Intermolecular autophosphorylation of ATM within dimeric ATM complexes, Caenorhabditis elegans" GO:0046853 : inositol or phosphatidylinositol phosphorylation - def: The process of introducing a phosphate group into inositol or a phosphatidylinositol. Inositol is the cyclic alcohol 1,2,3,4,5,6-cyclohexanehexol, which is widely distributed in nature and acts as a growth factor in animals and microorganisms. + def: OBSOLETE. The process of introducing a phosphate group into inositol or a phosphatidylinositol. Inositol is the cyclic alcohol 1,2,3,4,5,6-cyclohexanehexol, which is widely distributed in nature and acts as a growth factor in animals and microorganisms. + comment: This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids. - subset: gosubset_prok - is_a: GO:0006020 - is_a: GO:0046835 + is_obsolete: true + consider: GO:0046854 + consider: GO:0052746 GO:0046920 : alpha-(1->3)-fucosyltransferase activity - name: alpha(1,3)-fucosyltransferase activity + name: alpha-(1->3)-fucosyltransferase activity - def: Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha(1,3)-linkage. + def: Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->6) linkage. + synonym: "alpha(1,3)-fucosyltransferase activity" EXACT [] + synonym: "alpha-(1,3)-fucosyltransferase activity" EXACT [] + synonym: "alpha-1,3-fucosyltransferase activity" EXACT [] GO:0046921 : alpha-(1->6)-fucosyltransferase activity - name: alpha(1,6)-fucosyltransferase activity + name: alpha-(1->6)-fucosyltransferase activity - def: Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha(1,6)-linkage. + def: Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->6) linkage. + synonym: "alpha(1,6)-fucosyltransferase activity" EXACT [] + synonym: "alpha-(1,6)-fucosyltransferase activity" EXACT [] + synonym: "alpha-1,6-fucosyltransferase activity" EXACT [] GO:0046933 : hydrogen ion transporting ATP synthase activity, rotational mechanism - xref: Reactome:REACT_94502 "ATP is synthesized from ADP and Pi by ATPase, Taeniopygia guttata" GO:0046934 : phosphatidylinositol-4,5-bisphosphate 3-kinase activity - xref: Reactome:REACT_83904 "PI3K converts Phosphatidylinositol-4,5-bisphosphate to Phosphatidylinositol-3,4,5-trisphosphate, Bos taurus" - xref: Reactome:REACT_84814 "PI3K converts Phosphatidylinositol-4,5-bisphosphate to Phosphatidylinositol-3,4,5-trisphosphate, Mus musculus" - xref: Reactome:REACT_80332 "PI3K converts Phosphatidylinositol-4,5-bisphosphate to Phosphatidylinositol-3,4,5-trisphosphate, Canis familiaris" - xref: Reactome:REACT_92080 "PI3K catalyses the phosphorylation of PIP2 to PIP3, Drosophila melanogaster" - xref: Reactome:REACT_12636 "PI3K converts Phosphatidylinositol-4,5-bisphosphate to Phosphatidylinositol-3,4,5-trisphosphate, Homo sapiens" - xref: Reactome:REACT_94133 "PI3K converts Phosphatidylinositol-4,5-bisphosphate to Phosphatidylinositol-3,4,5-trisphosphate, Danio rerio" - xref: Reactome:REACT_32593 "PI3K converts Phosphatidylinositol-4,5-bisphosphate to Phosphatidylinositol-3,4,5-trisphosphate, Rattus norvegicus" - xref: Reactome:REACT_100772 "PI3K converts Phosphatidylinositol-4,5-bisphosphate to Phosphatidylinositol-3,4,5-trisphosphate, Xenopus tropicalis" - xref: Reactome:REACT_110694 "PI3K converts Phosphatidylinositol-4,5-bisphosphate to Phosphatidylinositol-3,4,5-trisphosphate, Taeniopygia guttata" - xref: Reactome:REACT_90594 "PI3K converts Phosphatidylinositol-4,5-bisphosphate to Phosphatidylinositol-3,4,5-trisphosphate, Gallus gallus" + xref: Reactome:REACT_115133 "PI3K phosphorylates PIP2 to PIP3, Xenopus tropicalis" + xref: Reactome:REACT_90594 "PIK3 converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3), Gallus gallus" + xref: Reactome:REACT_84814 "PIK3 converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3), Mus musculus" + xref: Reactome:REACT_32593 "PIK3 converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3), Rattus norvegicus" + xref: Reactome:REACT_94133 "PIK3 converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3), Danio rerio" + xref: Reactome:REACT_100772 "PIK3 converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3), Xenopus tropicalis" + xref: Reactome:REACT_110694 "PIK3 converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3), Taeniopygia guttata" + xref: Reactome:REACT_12636 "PIK3 converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3), Homo sapiens" + xref: Reactome:REACT_83904 "PIK3 converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3), Bos taurus" + xref: Reactome:REACT_80332 "PIK3 converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3), Canis familiaris" - is_a: GO:0035004 + is_a: GO:0052813 GO:0046950 : cellular ketone body metabolic process - xref: Reactome:REACT_84796 "Ketone body metabolism, Sus scrofa" + xref: Reactome:REACT_107371 "Ketone body metabolism, Sus scrofa" GO:0046951 : ketone body biosynthetic process - xref: Reactome:REACT_32527 "Synthesis of Ketone Bodies, Sus scrofa" + xref: Reactome:REACT_92114 "Synthesis of Ketone Bodies, Sus scrofa" GO:0046952 : ketone body catabolic process - xref: Reactome:REACT_33641 "Utilization of Ketone Bodies, Oryza sativa" - xref: Reactome:REACT_79469 "Utilization of Ketone Bodies, Arabidopsis thaliana" - xref: Reactome:REACT_96439 "Utilization of Ketone Bodies, Sus scrofa" + xref: Reactome:REACT_33137 "Utilization of Ketone Bodies, Sus scrofa" GO:0047057 : vitamin-K-epoxide reductase (warfarin-sensitive) activity - xref: Reactome:REACT_85801 "vitamin K epoxide -> vitamin K hydroquinone, Sus scrofa" + xref: Reactome:REACT_106636 "vitamin K epoxide -> vitamin K hydroquinone, Sus scrofa" + xref: Reactome:REACT_113699 "vitamin K epoxide -> vitamin K hydroquinone, Drosophila melanogaster" GO:0047069 : 7,8-dihydroxykynurenate 8,8a-dioxygenase activity + synonym: "7,8-dihydroxykynurenate:oxygen 8,8alpha-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.10] GO:0047106 : 4-hydroxyphenylacetaldehyde dehydrogenase activity - is_a: GO:0016620 + is_a: GO:0004029 GO:0047107 : gamma-guanidinobutyraldehyde dehydrogenase activity - is_a: GO:0016620 + is_a: GO:0004029 GO:0047207 : 1,2-beta-fructan 1F-fructosyltransferase activity - def: Catalysis of the reaction: (1,2-beta-D-fructosyl)(n) + (1,2-beta-D-fructosyl)(m) = (1,2-beta-D-fructosyl)(n+1) + (1,2-beta-D-fructosyl)(m-1). + def: Catalysis of the reaction: [(1->2)-beta-D-fructosyl](n) + [(1->2)-beta-D-fructosyl](m) = [(1->2)-beta-D-fructosyl](n+1) + [(1->2)-beta-D-fructosyl](m-1). GO:0047252 : beta-mannosylphosphodecaprenol-mannooligosaccharide 6-mannosyltransferase activity - def: Catalysis of the reaction: 1,6-alpha-D-mannosyloligodaccharide + beta-D-mannosylphosphodecaprenol = 1,6-alpha-D-mannosyl-1,6-alpha-D-mannosyl-oligosaccharide + decaprenol phosphate. + def: Catalysis of the reaction: (1->6)-alpha-D-mannosyloligosaccharide + beta-D-mannosylphosphodecaprenol = (1->6)-alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-oligosaccharide + decaprenol phosphate. GO:0047255 : galactogen 6-beta-galactosyltransferase activity - synonym: "beta-(1-6)-D-galactosyltransferase activity" EXACT [EC:2.4.1.205] + synonym: "beta-(1,6)-D-galactosyltransferase activity" EXACT [EC:2.4.1.205] GO:0047264 : heteroglycan alpha-mannosyltransferase activity - def: Catalysis of the reactions: heteroglycan + GDP-mannose = 1,2-alpha-D-mannosylheteroglycan + GDP, and heteroglycan + GDP-mannose = 1,3-alpha-D-mannosylheteroglycan + GDP. + def: Catalysis of the reaction: heteroglycan + GDP-mannose = alpha-D-mannosylheteroglycan + GDP. - xref: MetaCyc:2.4.1.48-RXN GO:0047290 : (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity - synonym: "neuac-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase activity" EXACT [EC:2.4.99.7] GO:0047309 : dihydroxyphenylalanine transaminase activity - synonym: "dopa aminotransferase activity" EXACT [EC:2.6.1.49] GO:0047360 : undecaprenyl-phosphate galactose phosphotransferase activity - synonym: "Poly(isoprenol)-phosphate galactosephosphotransferase activity" EXACT [EC:2.7.8.6] GO:0047372 : acylglycerol lipase activity - xref: Reactome:REACT_86016 "2-AG hydrolysis to arachidonate by MAGL, Dictyostelium discoideum" - xref: Reactome:REACT_95587 "2-acylglycerol + H2O -> glycerol + fatty acid, Saccharomyces cerevisiae" + xref: Reactome:REACT_113210 "Digestion of triacylglycerols by extracellular PTL:colipase, Gallus gallus" + xref: Reactome:REACT_112247 "Digestion of diacylglycerols by extracellular PTL:colipase, Xenopus tropicalis" + xref: Reactome:REACT_112608 "2-AG hydrolysis to arachidonate by MAGL, Arabidopsis thaliana" + xref: Reactome:REACT_112520 "DAG is metabolized by DAGL to 2-AG, Arabidopsis thaliana" + xref: Reactome:REACT_115325 "DAG is metabolized by DAGL to 2-AG, Caenorhabditis elegans" + xref: Reactome:REACT_114438 "2-acylglycerol + H2O -> glycerol + fatty acid, Staphylococcus aureus N315" + xref: Reactome:REACT_94131 "2-acylglycerol + H2O -> glycerol + fatty acid, Saccharomyces cerevisiae" + xref: Reactome:REACT_81812 "2-AG hydrolysis to arachidonate by MAGL, Dictyostelium discoideum" + xref: Reactome:REACT_114496 "Digestion of triacylglycerols by extracellular PTL:colipase, Xenopus tropicalis" + xref: Reactome:REACT_113735 "2-acylglycerol + H2O -> glycerol + fatty acid, Arabidopsis thaliana" + xref: Reactome:REACT_114762 "Digestion of diacylglycerols by extracellular PTL:colipase, Gallus gallus" + xref: Reactome:REACT_112674 "DAG is metabolized by DAGL to 2-AG, Oryza sativa" + xref: Reactome:REACT_115200 "2-AG hydrolysis to arachidonate by MAGL, Oryza sativa" + xref: Reactome:REACT_115057 "2-AG hydrolysis to arachidonate by MAGL, Staphylococcus aureus N315" + xref: Reactome:REACT_114842 "2-acylglycerol + H2O -> glycerol + fatty acid, Oryza sativa" GO:0047379 : ADP-dependent short-chain-acyl-CoA hydrolase activity - synonym: "propionyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.18] - synonym: "propionyl-CoA thioesterase activity" EXACT [EC:3.1.2.18] - synonym: "propionyl-CoA hydrolase activity" EXACT [EC:3.1.2.18] - synonym: "short-chain acyl-CoA hydrolase activity" EXACT [EC:3.1.2.18] - synonym: "short-chain acyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.18] - synonym: "short-chain acyl-CoA thioesterase activity" EXACT [EC:3.1.2.18] + synonym: "ADP-dependent propionyl coenzyme A hydrolase activity" NARROW [EC:3.1.2.18] + synonym: "ADP-dependent propionyl-CoA thioesterase activity" NARROW [EC:3.1.2.18] + synonym: "ADP-dependent short-chain acyl-CoA thioesterase activity" EXACT [EC:3.1.2.18] + synonym: "ADP-dependent propionyl-CoA hydrolase activity" NARROW [EC:3.1.2.18] + synonym: "ADP-dependent short-chain acyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.18] + synonym: "ADP-dependent short-chain acyl-CoA hydrolase activity" EXACT [EC:3.1.2.18] GO:0047380 : ADP-dependent medium-chain-acyl-CoA hydrolase activity - synonym: "medium-chain acyl-thioester hydrolase activity" EXACT [EC:3.1.2.19] - synonym: "medium-chain acyl-CoA hydrolase activity" EXACT [EC:3.1.2.19] - synonym: "medium-chain hydrolase activity" EXACT [EC:3.1.2.19] - synonym: "medium-chain acyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.19] - synonym: "myristoyl-CoA thioesterase activity" EXACT [EC:3.1.2.19] + synonym: "ADP-dependent medium-chain acyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.19] + synonym: "ADP-dependent medium-chain acyl-CoA hydrolase activity" EXACT [EC:3.1.2.19] + synonym: "ADP-dependent medium-chain hydrolase activity" EXACT [EC:3.1.2.19] + synonym: "ADP-dependent medium-chain acyl-thioester hydrolase activity" EXACT [EC:3.1.2.19] + synonym: "ADP-dependent myristoyl-CoA thioesterase activity" NARROW [EC:3.1.2.19] GO:0047470 : (1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase activity - def: Catalysis of the reaction: 4-(1,4-alpha-D-glucosyl)(n-1)-D-glucose = 1-alpha-D-(1,4-alpha-D-glucosyl)(n-1)-alpha-D-glucopyranoside. + def: Catalysis of the reaction: 4-[(1->4)-alpha-D-glucosyl](n-1)-D-glucose = 1-alpha-D-[(1->4)-alpha-D-glucosyl](n-1)-alpha-D-glucopyranoside. GO:0047514 : 1,3-beta-D-glucan phosphorylase activity - def: Catalysis of the reaction: 1,3-beta-D-glucosyl(n) + phosphate = 1,3-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate; substrates include laminarin. + def: Catalysis of the reaction: [(1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate; substrates include laminarin. GO:0047515 : 1,3-beta-oligoglucan phosphorylase activity - def: Catalysis of the reaction: oligomeric 1,3-beta-D-glucosyl(n) + phosphate = 1,3-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate. + def: Catalysis of the reaction: [oligomeric (1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate. GO:0047517 : 1,4-beta-D-xylan synthase activity - def: Catalysis of the reaction: UDP-D-xylose + 1,4-beta-D-xylan(n) = UDP + 1,4-beta-D-xylan(n+1). + def: Catalysis of the reaction: UDP-D-xylose + [(1->4)-beta-D-xylan](n) = UDP + [(1->4)-beta-D-xylan](n+1). GO:0047536 : 2-aminoadipate transaminase activity + xref: Reactome:REACT_112934 "alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate, Escherichia coli" + xref: Reactome:REACT_113111 "alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate, Staphylococcus aureus N315" + xref: Reactome:REACT_114940 "alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate, Schizosaccharomyces pombe" + xref: Reactome:REACT_113427 "alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate, Saccharomyces cerevisiae" GO:0047551 : 2-oxoaldehyde dehydrogenase (NAD) activity - is_a: GO:0016620 + is_a: GO:0004029 GO:0047552 : 2-oxoaldehyde dehydrogenase (NADP+) activity - is_a: GO:0016620 + is_a: GO:0033721 GO:0047555 : 3',5'-cyclic-GMP phosphodiesterase activity + xref: Reactome:REACT_115190 "cGMP is degraded by PDEs, Plasmodium falciparum" GO:0047560 : 3-dehydrosphinganine reductase activity - xref: Reactome:REACT_80028 "3-ketosphinganine + NADPH + H+ => sphinganine + NADP+, Dictyostelium discoideum" - xref: Reactome:REACT_106626 "3-ketosphinganine + NADPH + H+ => sphinganine + NADP+, Schizosaccharomyces pombe" - xref: Reactome:REACT_34769 "3-ketosphinganine + NADPH + H+ => sphinganine + NADP+, Mycobacterium tuberculosis" - xref: Reactome:REACT_82369 "3-ketosphinganine + NADPH + H+ => sphinganine + NADP+, Saccharomyces cerevisiae" + xref: Reactome:REACT_104625 "3-ketosphinganine + NADPH + H+ => sphinganine + NADP+, Dictyostelium discoideum" GO:0047617 : acyl-CoA hydrolase activity + alt_id: GO:0008778 + alt_id: GO:0016291 + alt_id: GO:0016292 + synonym: "acyl-CoA thioesterase I activity" NARROW [] + synonym: "acyl-CoA thiolesterase activity" EXACT [] + synonym: "acyl-CoA thioesterase activity" EXACT [] + synonym: "acyl-CoA thioesterase II activity" NARROW [] + xref: EC:3.1.2.- GO:0047657 : alpha-1,3-glucan synthase activity - synonym: "UDPglucose:alpha-D-(1-3)-glucan 3-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.183] - synonym: "UDP-glucose:alpha-D-(1-3)-glucan 3-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.183] + synonym: "UDP-glucose:alpha-D-(1->3)-glucan 3-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.183] + synonym: "UDPglucose:alpha-D-(1->3)-glucan 3-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.183] GO:0047683 : aryl-aldehyde dehydrogenase (NADP+) activity - is_a: GO:0016620 + is_a: GO:0033721 GO:0047712 : Cypridina-luciferin 2-monooxygenase activity - synonym: "cypridina-type luciferase activity" EXACT [EC:1.13.12.6] GO:0047787 : delta4-3-oxosteroid 5beta-reductase activity - synonym: "delta-4-3-oxosteroid 5-beta-reductase activity" EXACT [] + synonym: "delta4-3-oxosteroid 5-beta-reductase activity" EXACT [] GO:0047911 : galacturan 1,4-alpha-galacturonidase activity - def: Catalysis of the reaction: 1,4-alpha-D-galacturonide(n) + H2O = 1,4-alpha-D-galacturonide(n-1) + D-galacturonate. + def: Catalysis of the reaction: [(1->4)-alpha-D-galacturonide](n) + H2O = [(1->4)-alpha-D-galacturonide](n-1) + D-galacturonate. - synonym: "galacturan 1,4-a-galacturonidase activity" EXACT [] + synonym: "galacturan alpha-1,4-galacturonidase activity" EXACT [] GO:0047962 : glycine N-benzoyltransferase activity - xref: Reactome:REACT_87885 "salicylate-CoA + glycine => salicyluric acid + Coenzyme A, Sus scrofa" - xref: Reactome:REACT_103512 "benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A, Sus scrofa" + xref: Reactome:REACT_81307 "salicylate-CoA + glycine => salicyluric acid + Coenzyme A, Sus scrofa" + xref: Reactome:REACT_100176 "benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A, Sus scrofa" GO:0047969 : glyoxylate oxidase activity + xref: Reactome:REACT_112040 "Conversion of glyoxylate to oxalate, Dictyostelium discoideum" + xref: Reactome:REACT_114948 "Conversion of glyoxylate to oxalate, Oryza sativa" + xref: Reactome:REACT_112724 "Conversion of glyoxylate to oxalate, Drosophila melanogaster" + xref: Reactome:REACT_113190 "Conversion of glyoxylate to oxalate, Escherichia coli" + xref: Reactome:REACT_113242 "Conversion of glyoxylate to oxalate, Mycobacterium tuberculosis" + xref: Reactome:REACT_112588 "Conversion of glyoxylate to oxalate, Arabidopsis thaliana" GO:0048011 : nerve growth factor receptor signaling pathway - xref: Reactome:REACT_34527 "Signalling by NGF, Sus scrofa" + xref: Reactome:REACT_112151 "Signalling by NGF, Plasmodium falciparum" + xref: Reactome:REACT_112852 "p75 NTR receptor-mediated signalling, Dictyostelium discoideum" + xref: Reactome:REACT_33617 "Signalling by NGF, Sus scrofa" GO:0048106 : establishment of thoracic bristle planar orientation - name: establishment of body bristle planar orientation + name: establishment of thoracic bristle planar orientation + synonym: "establishment of body bristle planar orientation" EXACT [GOC:bf] GO:0048205 : COPI coating of Golgi vesicle - xref: Reactome:REACT_33523 "COPI Mediated Transport, Schizosaccharomyces pombe" + xref: Reactome:REACT_34581 "COPI Mediated Transport, Schizosaccharomyces pombe" GO:0048208 : COPII vesicle coating - xref: Reactome:REACT_104797 "COPII (Coat Protein 2) Mediated Vesicle Transport, Plasmodium falciparum" - xref: Reactome:REACT_109280 "COPII (Coat Protein 2) Mediated Vesicle Transport, Caenorhabditis elegans" + xref: Reactome:REACT_83562 "COPII (Coat Protein 2) Mediated Vesicle Transport, Plasmodium falciparum" GO:0048718 : cibarial fish-trap bristle morphogenesis - name: fish trap bristle morphogenesis + name: cibarial fish-trap bristle morphogenesis - def: The process in which the anatomical structures of a fish trap bristle are generated and organized. + def: The process in which the anatomical structures of a cibarial fish-trap bristle are generated and organized. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium. + synonym: "fish trap bristle morphogenesis" RELATED [GOC:rc] GO:0048725 : cibarial fish-trap bristle development - name: fish trap bristle development + name: cibarial fish-trap bristle development - def: The process whose specific outcome is the progression of the fish trap bristle over time, from its formation to the mature structure. + def: The process whose specific outcome is the progression of the cibarial fish-trap bristle over time, from its formation to the mature structure. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium. + synonym: "fish-trap bristle development" EXACT [GOC:rc] GO:0050061 : long-chain-aldehyde dehydrogenase activity - def: Catalysis of the reaction: a long-chain aldehyde + NAD+ = a long-chain carboxylate + NADH + H+. + def: Catalysis of the reaction: a long-chain aldehyde + NAD+ = a long-chain carboxylate + NADH + H+. A long-chain aldehyde is one with more than 12 carbons. - is_a: GO:0016620 + is_a: GO:0004029 GO:0050145 : nucleoside phosphate kinase activity - xref: Reactome:REACT_34318 "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP [CMPK1], Caenorhabditis elegans" - xref: Reactome:REACT_79145 "(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP [CMPK1], Caenorhabditis elegans" - xref: Reactome:REACT_85344 "dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK], Caenorhabditis elegans" + xref: Reactome:REACT_112761 "(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP [CMPK1], Escherichia coli" + xref: Reactome:REACT_83351 "(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP [CMPK1], Caenorhabditis elegans" + xref: Reactome:REACT_88127 "dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK], Caenorhabditis elegans" + xref: Reactome:REACT_90614 "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP [CMPK1], Caenorhabditis elegans" + xref: Reactome:REACT_112506 "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP [CMPK1], Escherichia coli" GO:0050197 : phytanate-CoA ligase activity + xref: Reactome:REACT_114248 "phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate, Saccharomyces cerevisiae" + xref: Reactome:REACT_113403 "phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate, Taeniopygia guttata" GO:0050248 : Renilla-luciferin 2-monooxygenase activity - synonym: "renilla-type luciferase activity" EXACT [EC:1.13.12.5] GO:0050269 : coniferyl-aldehyde dehydrogenase activity - is_a: GO:0016620 + is_a: GO:0004030 GO:0050291 : sphingosine N-acyltransferase activity + xref: Reactome:REACT_115485 "sphinganine + stearyl-CoA => dihydroceramide + CoASH, Drosophila melanogaster" GO:0050294 : steroid sulfotransferase activity + xref: Reactome:REACT_112914 "beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP, Danio rerio" + xref: Reactome:REACT_115144 "beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP, Gallus gallus" GO:0050327 : testosterone 17-beta-dehydrogenase (NAD+) activity - xref: Reactome:REACT_78645 "Reduction of androstenedione to testosterone, Caenorhabditis elegans" + xref: Reactome:REACT_112435 "Reduction of androstenedione to testosterone, Mycobacterium tuberculosis" GO:0050353 : trimethyllysine dioxygenase activity - xref: Reactome:REACT_105506 "trimethyllysine + alpha-ketoglutarate + O2 => beta-hydroxy-trimethyllysine + succinate + CO2, Saccharomyces cerevisiae" - xref: Reactome:REACT_102702 "trimethyllysine + alpha-ketoglutarate + O2 => beta-hydroxy-trimethyllysine + succinate + CO2, Bos taurus" + xref: Reactome:REACT_97973 "trimethyllysine + alpha-ketoglutarate + O2 => beta-hydroxy-trimethyllysine + succinate + CO2, Bos taurus" GO:0050390 : valine decarboxylase activity - synonym: "l-valine carboxy-lyase activity" EXACT [EC:4.1.1.14] GO:0050397 : Watasenia-luciferin 2-monooxygenase activity - synonym: "watasenia-type luciferase activity" EXACT [EC:1.13.12.8] GO:0050427 : 3'-phosphoadenosine 5'-phosphosulfate metabolic process - xref: Reactome:REACT_29071 "Cytosolic sulfonation of small molecules, Saccharomyces cerevisiae" - xref: Reactome:REACT_105535 "Cytosolic sulfonation of small molecules, Schizosaccharomyces pombe" + xref: Reactome:REACT_114637 "Cytosolic sulfonation of small molecules, Escherichia coli" GO:0050428 : 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process - xref: Reactome:REACT_107642 "Formation of PAPS, Saccharomyces cerevisiae" - xref: Reactome:REACT_97279 "Formation of PAPS, Schizosaccharomyces pombe" + xref: Reactome:REACT_114402 "Formation of PAPS, Escherichia coli" GO:0050442 : 3-propylmalate synthase activity - synonym: "n-propylmalate synthase activity" EXACT [EC:2.3.3.12] GO:0050471 : uracilylalanine synthase activity - synonym: "willardiine synthase activity" EXACT [EC:2.5.1.53] GO:0050500 : 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase activity - def: Catalysis of the reaction: phosphate + beta-D-galactopyranosyl-(1,3)-N-acetyl-D-glucosamine = N-acetyl-D-glucosamine + alpha-D-galactopyranose 1-phosphate. + def: Catalysis of the reaction: phosphate + beta-D-galactopyranosyl-(1->3)-N-acetyl-D-glucosamine = N-acetyl-D-glucosamine + alpha-D-galactopyranose 1-phosphate. - synonym: "1,3-b-galactosyl-N-acetylhexosamine phosphorylase activity" EXACT [] + synonym: "beta-D-galactopyranosyl-(1,3)-N-acetyl-D-hexosamine:phosphate galactosyltransferase activity" EXACT [EC:2.4.1.211] + synonym: "beta-1,3-galactosyl-N-acetylhexosamine phosphorylase activity" EXACT [] GO:0050501 : hyaluronan synthase activity - def: Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl(1,4)beta-D-glucuronosyl(1,3)](n) + 2n UDP. + def: Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)](n) + 2n UDP. - synonym: "HAS activity" EXACT [EC:2.4.1.212] + synonym: "HAS activity" BROAD [EC:2.4.1.212] + synonym: "alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1,3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1,4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity" EXACT [EC:2.4.1.212] GO:0050512 : lactosylceramide 4-alpha-galactosyltransferase activity - synonym: "Gal-beta-1-4Glc-beta-1-Cer alpha-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.228] - synonym: "galbeta1-4Glcbeta1-Cer alpha1,4-galactosyltransferase activity" EXACT [EC:2.4.1.228] + synonym: "Gal-beta-1,4-Glc-beta-1-Cer alpha-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.228] + synonym: "Gal-beta-(1,4)-Glc-beta-1-Cer alpha-(1,4)-galactosyltransferase activity" EXACT [EC:2.4.1.228] GO:0050513 : glycoprotein 2-beta-D-xylosyltransferase activity - synonym: "beta1,2-xylosyltransferase activity" EXACT [EC:2.4.2.38] + synonym: "1,2-beta-xylosyltransferase activity" EXACT [EC:2.4.2.38] GO:0050567 : glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity - synonym: "glu-tRNA(gln) amidotransferase activity" EXACT [EC:6.3.5.-] GO:0050569 : glycolaldehyde dehydrogenase activity - is_a: GO:0016620 + is_a: GO:0004029 GO:0050613 : delta14-sterol reductase activity + xref: Reactome:REACT_113353 "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR], Drosophila melanogaster" + xref: Reactome:REACT_115123 "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2], Drosophila melanogaster" GO:0050614 : delta24-sterol reductase activity - xref: Reactome:REACT_33198 "Reduction of desmosterol to cholesterol, Caenorhabditis elegans" GO:0050632 : propionyl-CoA C2-trimethyltridecanoyltransferase activity - xref: Reactome:REACT_81883 "3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA, Drosophila melanogaster" - xref: Reactome:REACT_88640 "Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA, Drosophila melanogaster" - xref: Reactome:REACT_81247 "Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA, Drosophila melanogaster" - xref: Reactome:REACT_29142 "3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA, Sus scrofa" + xref: Reactome:REACT_106600 "3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA, Sus scrofa" GO:0050633 : acetyl-CoA C-myristoyltransferase activity - xref: Reactome:REACT_110772 "3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA, Escherichia coli" - xref: Reactome:REACT_94959 "3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA, Escherichia coli" - xref: Reactome:REACT_100645 "3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA, Caenorhabditis elegans" - xref: Reactome:REACT_34047 "3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA, Escherichia coli" - xref: Reactome:REACT_106290 "3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA, Escherichia coli" - xref: Reactome:REACT_100898 "3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA, Escherichia coli" - xref: Reactome:REACT_79953 "3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA, Caenorhabditis elegans" - xref: Reactome:REACT_87877 "3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA, Escherichia coli" - xref: Reactome:REACT_51199 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Bos taurus" + xref: Reactome:REACT_103468 "3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA, Caenorhabditis elegans" + xref: Reactome:REACT_90562 "3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA, Caenorhabditis elegans" + xref: Reactome:REACT_99776 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Bos taurus" GO:0050772 : positive regulation of axonogenesis + xref: Reactome:REACT_112731 "Axonal growth stimulation, Danio rerio" + xref: Reactome:REACT_113936 "Axonal growth stimulation, Rattus norvegicus" GO:0050796 : regulation of insulin secretion - xref: Reactome:REACT_79002 "Regulation of Insulin Secretion, Plasmodium falciparum" + xref: Reactome:REACT_114911 "Regulation of Insulin Secretion, Arabidopsis thaliana" + xref: Reactome:REACT_115218 "Regulation of Insulin Secretion, Schizosaccharomyces pombe" + xref: Reactome:REACT_114277 "Regulation of Insulin Secretion, Saccharomyces cerevisiae" + xref: Reactome:REACT_114254 "Regulation of Insulin Secretion, Oryza sativa" GO:0050852 : T cell receptor signaling pathway + xref: Reactome:REACT_112881 "TCR signaling, Plasmodium falciparum" GO:0050999 : regulation of nitric-oxide synthase activity - xref: Reactome:REACT_89487 "eNOS activation and regulation, Dictyostelium discoideum" - xref: Reactome:REACT_28565 "eNOS activation, Staphylococcus aureus N315" - xref: Reactome:REACT_87573 "eNOS activation and regulation, Staphylococcus aureus N315" - xref: Reactome:REACT_84429 "eNOS activation, Drosophila melanogaster" - xref: Reactome:REACT_82873 "eNOS activation, Escherichia coli" - xref: Reactome:REACT_32691 "eNOS activation, Dictyostelium discoideum" - xref: Reactome:REACT_88732 "eNOS activation and regulation, Drosophila melanogaster" - xref: Reactome:REACT_104392 "eNOS activation and regulation, Escherichia coli" + xref: Reactome:REACT_114898 "eNOS activation, Taeniopygia guttata" + xref: Reactome:REACT_112087 "eNOS activation and regulation, Taeniopygia guttata" GO:0051084 : 'de novo' posttranslational protein folding - xref: Reactome:REACT_30483 "Protein folding, Plasmodium falciparum" + xref: Reactome:REACT_90293 "Protein folding, Plasmodium falciparum" GO:0051092 : positive regulation of NF-kappaB transcription factor activity + xref: Reactome:REACT_113766 "TAK1 activates NFkB by phosphorylation and activation of IKKs complex, Drosophila melanogaster" + xref: Reactome:REACT_113398 "TAK1 activates NFkB by phosphorylation and activation of IKKs complex, Taeniopygia guttata" GO:0051118 : glucan endo-1,3-alpha-glucosidase activity - def: Catalysis of the endohydrolysis of 1,3-alpha-D-glucosidic linkages in isolichenin, pseudonigeran and nigeran. + def: Catalysis of the endohydrolysis of (1->3)-alpha-D-glucosidic linkages in isolichenin, pseudonigeran and nigeran. GO:0051119 : sugar transmembrane transporter activity - xref: Reactome:REACT_81012 "GLUT7 and GLUT11 transport glucose and fructose, Drosophila melanogaster" + xref: Reactome:REACT_113992 "GLUT7 and GLUT11 transport glucose and fructose, Arabidopsis thaliana" + xref: Reactome:REACT_113932 "GLUT7 and GLUT11 transport glucose and fructose, Mycobacterium tuberculosis" + xref: Reactome:REACT_113009 "GLUT7 and GLUT11 transport glucose and fructose, Dictyostelium discoideum" + xref: Reactome:REACT_113132 "GLUT7 and GLUT11 transport glucose and fructose, Oryza sativa" + xref: Reactome:REACT_112187 "GLUT7 and GLUT11 transport glucose and fructose, Plasmodium falciparum" GO:0051139 : metal ion:hydrogen antiporter activity + xref: Reactome:REACT_112591 "NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages, Staphylococcus aureus N315" GO:0051149 : positive regulation of muscle cell differentiation + xref: Reactome:REACT_113620 "CDO in myogenesis, Caenorhabditis elegans" GO:0051168 : nuclear export + xref: Reactome:REACT_113944 "Nuclear export of snRNA transcripts, Danio rerio" + xref: Reactome:REACT_112801 "Nuclear export of snRNA transcripts, Drosophila melanogaster" GO:0051170 : nuclear import - xref: Reactome:REACT_86962 "snRNP nuclear import and release, Bos taurus" GO:0051394 : regulation of nerve growth factor receptor activity - is_a: GO:0043393 GO:0051395 : negative regulation of nerve growth factor receptor activity - is_a: GO:0032091 GO:0051396 : positive regulation of nerve growth factor receptor activity - is_a: GO:0032092 GO:0051421 : regulation of endo-1,4-beta-xylanase activity - def: Any process that modulates the frequency, rate or extent of endo-1,4-beta-xylanase activity, the catalysis of the endohydrolysis of 1,4-beta-D-xylosidic linkages in xylans. + def: Any process that modulates the frequency, rate or extent of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans. GO:0051422 : negative regulation of endo-1,4-beta-xylanase activity - def: Any process that stops or reduces the rate of endo-1,4-beta-xylanase activity, the catalysis of the endohydrolysis of 1,4-beta-D-xylosidic linkages in xylans. + def: Any process that stops or reduces the rate of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans. GO:0051423 : positive regulation of endo-1,4-beta-xylanase activity - def: Any process that activates or increases the frequency, rate or extent of endo-1,4-beta-xylanase activity, the catalysis of the endohydrolysis of 1,4-beta-D-xylosidic linkages in xylans. + def: Any process that activates or increases the frequency, rate or extent of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans. GO:0051436 : negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle - xref: Reactome:REACT_87706 "Association of Emi1 with Cdh1, Sus scrofa" - xref: Reactome:REACT_79948 "Phosphorylation of Cdh1 by Cyclin B1:Cdc2, Caenorhabditis elegans" - xref: Reactome:REACT_79515 "Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components, Caenorhabditis elegans" - xref: Reactome:REACT_106068 "Autodegradation of Cdh1 by Cdh1:APC/C, Arabidopsis thaliana" + xref: Reactome:REACT_113195 "Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components, Arabidopsis thaliana" + xref: Reactome:REACT_101227 "Association of Emi1 with Cdh1, Sus scrofa" + xref: Reactome:REACT_113042 "Phosphorylation of Cdh1 by Cyclin B1:Cdc2, Saccharomyces cerevisiae" + xref: Reactome:REACT_113808 "Phosphorylation of Cdh1 by Cyclin B1:Cdc2, Schizosaccharomyces pombe" + xref: Reactome:REACT_114563 "Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components, Oryza sativa" GO:0051437 : positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle - xref: Reactome:REACT_87110 "Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1, Drosophila melanogaster" - xref: Reactome:REACT_101549 "SCF-beta-TrCP mediated degradation of Emi1, Schizosaccharomyces pombe" - xref: Reactome:REACT_93035 "SCF-beta-TrCP mediated degradation of Emi1, Caenorhabditis elegans" + xref: Reactome:REACT_112598 "Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1, Bos taurus" + xref: Reactome:REACT_113510 "Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1, Arabidopsis thaliana" GO:0051439 : regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle - xref: Reactome:REACT_103190 "Regulation of APC/C activators between G1/S and early anaphase, Caenorhabditis elegans" + xref: Reactome:REACT_114183 "Regulation of APC/C activators between G1/S and early anaphase, Saccharomyces cerevisiae" GO:0051726 : regulation of cell cycle - xref: Reactome:REACT_81253 "Inactivation of Myt1 kinase, Saccharomyces cerevisiae" - xref: Reactome:REACT_96416 "Activation of Cdc25C, Dictyostelium discoideum" - xref: Reactome:REACT_85274 "Activation of Cdc25C, Danio rerio" + xref: Reactome:REACT_113569 "Activation of Cdc25C, Saccharomyces cerevisiae" + xref: Reactome:REACT_114323 "Activation of Cdc25C, Caenorhabditis elegans" + xref: Reactome:REACT_113990 "Activation of Cdc25C, Schizosaccharomyces pombe" + xref: Reactome:REACT_83089 "Inactivation of Myt1 kinase, Saccharomyces cerevisiae" + xref: Reactome:REACT_112480 "Inactivation of Wee1 kinase, Dictyostelium discoideum" GO:0051751 : alpha-1,4-mannosyltransferase activity - def: Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,4-linkage. + def: Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->4) linkage. GO:0051753 : mannan synthase activity - def: Catalysis of the reaction: mannan(n) + GDP-mannose = mannan(n+1) + GDP. This reaction is the formation of the beta-1,4-linked mannan backbone in substrates such as galactomannan. + def: Catalysis of the reaction: mannan(n) + GDP-mannose = mannan(n+1) + GDP. This reaction is the formation of the beta-(1->4)-linked mannan backbone in substrates such as galactomannan. GO:0051765 : inositol tetrakisphosphate kinase activity - is_a: GO:0004428 + is_a: GO:0016301 GO:0051766 : inositol trisphosphate kinase activity - is_a: GO:0004428 + is_a: GO:0016301 GO:0051818 : disruption of cells of other organism involved in symbiotic interaction + is_a: GO:0044364 GO:0051899 : membrane depolarization - xref: Reactome:REACT_81474 "Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels, Gallus gallus" + xref: Reactome:REACT_114683 "Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels, Xenopus tropicalis" GO:0052204 : negative regulation of molecular function in other organism involved in symbiotic interaction + is_a: GO:0044362 GO:0052205 : modulation of molecular function in other organism involved in symbiotic interaction + is_a: GO:0044359 GO:0052725 : inositol-1,3,4-trisphosphate 6-kinase activity - xref: Reactome:REACT_25214 "ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5/6-P4, Homo sapiens" GO:0052726 : inositol-1,3,4-trisphosphate 5-kinase activity - xref: Reactome:REACT_25214 "ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5/6-P4, Homo sapiens" GO:0052742 : phosphatidylinositol kinase activity - is_a: GO:0004428 + is_a: GO:0016301 GO:0052744 : phosphatidylinositol monophosphate phosphatase activity - is_a: GO:0004437 + is_a: GO:0016791 GO:0052745 : inositol phosphate phosphatase activity - is_a: GO:0004437 + is_a: GO:0016791 GO:0052756 : chitobiose phosphorylase activity - def: Catalysis of the reaction: chitobiose + phosphate = N-acetyl-D-glucosamine + N-acetyl-alpha-D-glucosamine 1-phosphate. This reaction is the phosphorolysis of chitobiose, (GlcNAc)2, a dimer of beta-1,4-linked glucosamine units. + def: Catalysis of the reaction: chitobiose + phosphate = N-acetyl-D-glucosamine + N-acetyl-alpha-D-glucosamine 1-phosphate. This reaction is the phosphorolysis of chitobiose, (GlcNAc)2, a dimer of beta-(1->4) linked glucosamine units. GO:0052761 : exo-1,4-beta-D-glucosaminidase activity - def: Catalysis of the reaction: [beta-(1,4)-D-glucosamine]n-[N-acetyl-D-glucosamine]m = D-glucosamine + [beta-(1,4)-D-glucosamine](n-1)-[N-acetyl-D-glucosamine]m. This reaction is the hydrolysis of chitosan or chitosan oligosaccharides to remove a D-glucosamine residue from the non-reducing termini; chitosan is a linear polysaccharide composed of randomly distributed beta-(1,4)-linked D-glucosamine and N-acetyl-D-glucosamine units. + def: Catalysis of the reaction: [beta-(1->4)-D-glucosamine]n-[N-acetyl-D-glucosamine]m = D-glucosamine + [beta-(1->4)-D-glucosamine](n-1)-[N-acetyl-D-glucosamine]m. This reaction is the hydrolysis of chitosan or chitosan oligosaccharides to remove a D-glucosamine residue from the non-reducing termini; chitosan is a linear polysaccharide composed of randomly distributed beta-(1->4)-linked D-glucosamine and N-acetyl-D-glucosamine units. GO:0052762 : gellan lyase activity - def: Catalysis of the reaction: gellan = n beta-D-4-deoxy-delta4,5-GlcAp-(1,4)-beta-D-Glcp-(1,4)-alpha-L-Rhap-(1,3)-beta-D-Glcp. This reaction is the eliminative cleavage of beta-D-glucopyranosyl-(1,4)-beta-D-glucopyranosyluronate bonds of gellan backbone, releasing tetrasaccharides containing a 4-deoxy-4,5-unsaturated D-glucopyranosyluronic acid at the non-reducing end; in the product, the abbreviations are D-glucose (Glc), D-glucuronic acid (GlcA), and L-rhamnose (Rha). + def: Catalysis of the reaction: gellan = n beta-D-4-deoxy-delta4,5-GlcAp-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp. This reaction is the eliminative cleavage of beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyluronate bonds of gellan backbone, releasing tetrasaccharides containing a 4-deoxy-4,5-unsaturated D-glucopyranosyluronic acid at the non-reducing end; in the product, the abbreviations are D-glucose (Glc), D-glucuronic acid (GlcA), and L-rhamnose (Rha). GO:0052763 : ulvan lyase activity - def: Catalysis of the cleavage of a carbon-oxygen bond in ulvan, a carbohydrate composed of a repeating structure of [->4)-beta-D-GlcA-(1,4)-alpha-L-Rha 3S-(1,4)-alpha-L-IdoA-(1,4)-alpha-L-Rha 3S-(1->]n. Continued digest of ulvan with an enzyme that can catalyze this reaction results in ulvanobiouronic acid A 3-sulfate [->4)-beta-D-GlcpA-(1,4)-alpha-L-Rhap 3-sulfate-(1->]n with 4-deoxy-L-threo-hex-4-enopyranosiduronic acid at the non-reducing end. + def: Catalysis of the cleavage of a carbon-oxygen bond in ulvan, a carbohydrate composed of a repeating structure of [->4)-beta-D-GlcA-(1,4)-alpha-L-Rha 3S-(1->4)-alpha-L-IdoA-(1->4)-alpha-L-Rha 3S-(1-]n. Continued digest of ulvan with an enzyme that can catalyze this reaction results in ulvanobiouronic acid A 3-sulfate [->4)-beta-D-GlcpA-(1->4)-alpha-L-Rhap 3-sulfate-(1-]n with 4-deoxy-L-threo-hex-4-enopyranosiduronic acid at the non-reducing end. GO:0052764 : exo-oligoalginate lyase activity - def: Catalysis of the cleavage of glycosidic bonds through a beta-elimination reaction on alginate, a linear polysaccharide consisting of guluronate (G) and mannuronate (M) as the monomer constituents. An oligoalginate is a linear polymer of two, three or four units of (1,4) alpha-L-guluronic acid and beta-D-mannuronic acid, releasing monosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends. + def: Catalysis of the cleavage of glycosidic bonds through a beta-elimination reaction on alginate, a linear polysaccharide consisting of guluronate (G) and mannuronate (M) as the monomer constituents. An oligoalginate is a linear polymer of two, three or four units of (1->4)-alpha-L-guluronic acid and beta-D-mannuronic acid, releasing monosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends. GO:0052766 : mannoside alpha-1,4-mannosidase activity - def: Catalysis of the hydrolysis of the alpha-1,4 linkage of the terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. + def: Catalysis of the hydrolysis of the alpha-(1->4) linkage of the terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. GO:0052767 : mannosyl-oligosaccharide 1,6-alpha-mannosidase activity - def: Catalysis of the hydrolysis of the alpha-1,6 bonds of alpha-D-mannose residues in mannosyl-oligosaccharide. + def: Catalysis of the hydrolysis of the alpha-(1->6) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide. + synonym: "alpha-1,6-mannosyl-oligosaccharide alpha-D-mannohydrolase activity" EXACT [] GO:0052768 : mannosyl-oligosaccharide 1,3-alpha-mannosidase activity - def: Catalysis of the hydrolysis of the alpha-1,3 bonds of alpha-D-mannose residues in mannosyl-oligosaccharide. + def: Catalysis of the hydrolysis of the alpha-(1->3) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide. - synonym: "1,4-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity" EXACT [] - synonym: "1,4-alpha-mannosidase activity" BROAD [] - synonym: "alpha-1,4-mannosidase activity" BROAD [] + synonym: "1,3-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity" EXACT [] + synonym: "1,3-alpha-mannosidase activity" BROAD [] + synonym: "alpha-1,3-mannosyl-oligosaccharide alpha-D-mannohydrolase activity" EXACT [] + synonym: "alpha-1,3-mannosidase activity" BROAD [] GO:0052769 : beta-6-sulfate-N-acetylglucosaminidase activity + synonym: "beta-6-SO3-N-acetylglucosaminidase activity" BROAD [] GO:0052775 : endo-1,3-alpha-L-rhamnosidase activity - def: Catalysis of the reaction: R1-L-rhamnose-(1,3)-alpha-L-rhamnose-R2 + H2O = R1-L-rhamnose + L-rhamnose-R2. This reaction is the hydrolysis of an alpha-1,3-linkage between two rhamnose residues in a polysaccharide chain. + def: Catalysis of the reaction: R1-L-rhamnose-(1->3)-alpha-L-rhamnose-R2 + H2O = R1-L-rhamnose + L-rhamnose-R2. This reaction is the hydrolysis of an alpha-(1->3) linkage between two rhamnose residues in a polysaccharide chain. + synonym: "endo-(1->3)-alpha-L-rhamnosidase activity" EXACT [] + synonym: "endo-(1,3)-alpha-L-rhamnosidase activity" EXACT [] GO:0052786 : alpha-linked polysaccharide catabolism to maltotriose - def: The breakdown of large alpha-linked polysaccharides by hydrolysis of 1,4-alpha-D-glucosidic linkages to yield maltotriose. + def: The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltotriose. GO:0052787 : alpha-linked polysaccharide catabolism to maltopentaose - def: The breakdown of large alpha-linked polysaccharides by hydrolysis of 1,4-alpha-D-glucosidic linkages to yield maltopentaose. + def: The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltopentaose. GO:0052789 : mannan 1,3-beta-mannosidase activity - def: Catalysis of the hydrolysis of 1,3-beta-D-mannosidic linkages in mannans, releasing mannose. + def: Catalysis of the hydrolysis of (1->3)-beta-D-mannosidic linkages in mannans, releasing mannose. GO:0052790 : chitooligosaccharide deacetylase activity - def: Catalysis of the reaction: chitooligosaccharide with N-acetylglucosamine at nonreducing terminal + H2O = chitooligosaccharide with glucosamine at nonreducing terminal + acetate. This reaction is the deacetylation of a chitooligosaccharide at the nonreducing N-acetylglucosamine residue; chitooligosaccharide are composed of -1,4-linked-D-glucosamine (GlcN) and N-acetyl-D-glucosamine (GlcNAc) in varying proportions. + def: Catalysis of the reaction: chitooligosaccharide with N-acetylglucosamine at nonreducing terminal + H2O = chitooligosaccharide with glucosamine at nonreducing terminal + acetate. This reaction is the deacetylation of a chitooligosaccharide at the nonreducing N-acetylglucosamine residue; chitooligosaccharide are composed of (1->4)-linked D-glucosamine (GlcN) and N-acetyl-D-glucosamine (GlcNAc) in varying proportions. GO:0052794 : exo-alpha-(2->3)-sialidase activity - name: exo-alpha-(2,3)-sialidase activity + name: exo-alpha-(2->3)-sialidase activity + synonym: "exo-alpha-(2,3)-sialidase activity" EXACT [] + synonym: "exo-alpha-2,3-sialidase activity" EXACT [] GO:0052795 : exo-alpha-(2->6)-sialidase activity - name: exo-alpha-(2,6)-sialidase activity + name: exo-alpha-(2->6)-sialidase activity + synonym: "exo-alpha-(2,6)-sialidase activity" EXACT [] + synonym: "exo-alpha-2,6-sialidase activity" EXACT [] GO:0052796 : exo-alpha-(2->8)-sialidase activity - name: exo-alpha-(2,8)-sialidase activity + name: exo-alpha-(2->8)-sialidase activity + synonym: "exo-alpha-(2,8)-sialidase activity" EXACT [] + synonym: "exo-alpha-2,8-sialidase activity" EXACT [] GO:0055056 : D-glucose transmembrane transporter activity - xref: Reactome:REACT_83648 "Glucose transport by class III GLUTs, Drosophila melanogaster" - xref: Reactome:REACT_109737 "Glucose transport by class III GLUTs, Mycobacterium tuberculosis" - xref: Reactome:REACT_87643 "Glucose transport by class III GLUTs, Escherichia coli" - xref: Reactome:REACT_34322 "Glucose transport by class III GLUTs, Dictyostelium discoideum" - xref: Reactome:REACT_79045 "Glucose transport by class III GLUTs, Sus scrofa" + xref: Reactome:REACT_114069 "Glucose transport by class I GLUTs, Dictyostelium discoideum" + xref: Reactome:REACT_81510 "Glucose transport by class III GLUTs, Sus scrofa" + xref: Reactome:REACT_115387 "Glucose transport by class I GLUTs, Oryza sativa" + xref: Reactome:REACT_114121 "Glucose transport by class I GLUTs, Mycobacterium tuberculosis" + xref: Reactome:REACT_113478 "Glucose transport by class I GLUTs, Caenorhabditis elegans" + xref: Reactome:REACT_114492 "Glucose transport by class I GLUTs, Arabidopsis thaliana" + xref: Reactome:REACT_114352 "Glucose transport by class I GLUTs, Drosophila melanogaster" + xref: Reactome:REACT_113923 "Glucose transport by class I GLUTs, Plasmodium falciparum" GO:0055085 : transmembrane transport - xref: Reactome:REACT_28801 "Transmembrane transport of small molecules, Sus scrofa" - xref: Reactome:REACT_32562 "SLC-mediated transmembrane transport, Sus scrofa" + xref: Reactome:REACT_114546 "ABC-family proteins mediated transport, Staphylococcus aureus N315" + xref: Reactome:REACT_96633 "Transmembrane transport of small molecules, Sus scrofa" + xref: Reactome:REACT_114763 "ABC-family proteins mediated transport, Escherichia coli" + xref: Reactome:REACT_101975 "SLC-mediated transmembrane transport, Sus scrofa" + xref: Reactome:REACT_115378 "ABC-family proteins mediated transport, Mycobacterium tuberculosis" + xref: Reactome:REACT_114890 "ABC-family proteins mediated transport, Plasmodium falciparum" GO:0055086 : nucleobase-containing small molecule metabolic process - xref: Reactome:REACT_90371 "Metabolism of nucleotides, Sus scrofa" + xref: Reactome:REACT_31512 "Metabolism of nucleotides, Sus scrofa" GO:0060397 : JAK-STAT cascade involved in growth hormone signaling pathway + xref: Reactome:REACT_111133 "Growth hormone receptor signaling, Homo sapiens" GO:0060624 : regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process - name: regulation of ascospore wall 1,3-beta-D-glucan biosynthetic process + name: regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process - def: Any process that modulates the rate, frequency, or extent of ascospore wall 1,3-beta-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of 1,3-beta-glucans, compounds composed of glucose residues linked by 1,3-beta-D-glucosidic bonds, found in the walls of ascospores. + def: Any process that modulates the rate, frequency, or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D--glucosidic bonds, found in the walls of ascospores. + synonym: "regulation of ascospore wall 1,3-beta-D-glucan biosynthetic process" BROAD [] GO:0060634 : regulation of 4,6-pyruvylated galactose residue biosynthetic process - def: Any process that modulates the rate, frequency, or extent of 4,6-pyruvylated galactose residue biosynthetic process, the chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain. + def: Any process that modulates the rate, frequency, or extent of 4,6-pyruvylated galactose residue biosynthetic process, the chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-(1->3)-. The galactose residue is part of a larger polysaccharide chain. GO:0060635 : positive regulation of (1->3)-beta-D-glucan biosynthetic process - name: positive regulation of 1,3-beta-D-glucan biosynthetic process + name: positive regulation of (1->3)-beta-D-glucan biosynthetic process - def: Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta-1,3 glucans. + def: Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans. - synonym: "positive regulation of 1,3-beta-glucan biosynthetic process" BROAD [] + synonym: "positive regulation of 1,3-beta-D-glucan biosynthetic process" EXACT [] GO:0060636 : negative regulation of (1->3)-beta-D-glucan biosynthetic process - name: negative regulation of 1,3-beta-D-glucan biosynthetic process + name: negative regulation of (1->3)-beta-D-glucan biosynthetic process - def: Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta-1,3 glucans. + def: Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans. - synonym: "negative regulation of 1,3-beta-glucan biosynthetic process" BROAD [] + synonym: "negative regulation of 1,3-beta-D-glucan biosynthetic process" EXACT [] GO:0060917 : regulation of (1->6)-beta-D-glucan biosynthetic process - name: regulation of 1,6-beta-glucan biosynthetic process + name: regulation of (1->6)-beta-D-glucan biosynthetic process - def: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta-1,6 glucans. + def: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans. + synonym: "regulation of 1,6-beta-glucan biosynthetic process" EXACT [] GO:0070251 : pristanate-CoA ligase activity + xref: Reactome:REACT_113004 "pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate, Saccharomyces cerevisiae" + xref: Reactome:REACT_112851 "pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate, Taeniopygia guttata" GO:0070371 : ERK1 and ERK2 cascade + xref: Reactome:REACT_112819 "ERK2 activation, Dictyostelium discoideum" + xref: Reactome:REACT_112775 "ERK2 activation, Arabidopsis thaliana" + xref: Reactome:REACT_115367 "ERK2 activation, Oryza sativa" GO:0070380 : high mobility group box 1 receptor activity - is_a: GO:0070379 + relationship: has_part GO:0070379 GO:0070423 : nucleotide-binding oligomerization domain containing signaling pathway + xref: Reactome:REACT_112657 "NOD1/2 Signaling Pathway, Drosophila melanogaster" GO:0070506 : high-density lipoprotein particle receptor activity - is_a: GO:0008035 + relationship: has_part GO:0008035 GO:0070595 : (1->3)-alpha-glucan metabolic process - name: 1,3-alpha-glucan metabolic process + name: (1->3)-alpha-glucan metabolic process - def: The chemical reactions and pathways involving alpha-1,3 glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds. + def: The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds. + synonym: "1,3-alpha-glucan metabolic process" EXACT [GOC:mah] GO:0070596 : (1->3)-alpha-glucan biosynthetic process - name: 1,3-alpha-glucan biosynthetic process + name: (1->3)-alpha-glucan biosynthetic process - def: The chemical reactions and pathways resulting in the formation of alpha-1,3 glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds. + def: The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds. + synonym: "1,3-alpha-glucan biosynthetic process" EXACT [GOC:mah] GO:0070597 : cell wall (1->3)-alpha-glucan metabolic process - name: cell wall 1,3-alpha-glucan metabolic process + name: cell wall (1->3)-alpha-glucan metabolic process - def: The chemical reactions and pathways involving alpha-1,3 glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds, found in the walls of cells. + def: The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells. + synonym: "cell wall 1,3-alpha-glucan metabolic process" EXACT [GOC:mah] GO:0070598 : cell wall (1->3)-alpha-glucan biosynthetic process - name: cell wall 1,3-alpha-glucan biosynthetic process + name: cell wall (1->3)-alpha-glucan biosynthetic process - def: The chemical reactions and pathways resulting in the formation of 1,3-alpha-glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds, found in the walls of cells. + def: The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-glucosidic bonds, found in the walls of cells. + synonym: "cell wall 1,3-alpha-glucan biosynthetic process" EXACT [GOC:mah] GO:0070599 : fungal-type cell wall (1->3)-alpha-glucan metabolic process - name: fungal-type cell wall 1,3-alpha-glucan metabolic process + name: fungal-type cell wall (1->3)-alpha-glucan metabolic process - def: The chemical reactions and pathways involving alpha-1,3 glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds, found in the walls of ascospores. + def: The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores. + synonym: "ascospore wall 1,3-alpha-glucan metabolic process" EXACT [GOC:mah] GO:0070600 : fungal-type cell wall (1->3)-alpha-glucan biosynthetic process - name: fungal-type cell wall 1,3-alpha-glucan biosynthetic process + name: fungal-type cell wall (1->3)-alpha-glucan biosynthetic process - def: The chemical reactions and pathways resulting in the formation of 1,3-alpha-glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores. + def: The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores. + synonym: "fungal-type cell wall 1,3-alpha-glucan biosynthetic process" EXACT [GOC:mah] GO:0070605 : regulation of (1->3)-alpha-glucan metabolic process - name: regulation of 1,3-alpha-glucan metabolic process + name: regulation of (1->3)-alpha-glucan metabolic process - def: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving alpha-1,3 glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds. + def: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds. + synonym: "regulation of 1,3-alpha-glucan metabolic process" EXACT [GOC:mah] GO:0070606 : regulation of (1->3)-alpha-glucan biosynthetic process - name: regulation of 1,3-alpha-glucan biosynthetic process + name: regulation of (1->3)-alpha-glucan biosynthetic process - def: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of alpha-1,3 glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds. + def: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds. + synonym: "regulation of 1,3-alpha-glucan biosynthetic process" EXACT [GOC:mah] GO:0070607 : regulation of cell wall (1->3)-alpha-glucan metabolic process - name: regulation of cell wall 1,3-alpha-glucan metabolic process + name: regulation of cell wall (1->3)-alpha-glucan metabolic process - def: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving alpha-1,3 glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds, found in the walls of cells. + def: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells. + synonym: "regulation of cell wall 1,3-alpha-glucan metabolic process" EXACT [GOC:mah] GO:0070608 : regulation of cell wall (1->3)-alpha-glucan biosynthetic process - name: regulation of cell wall 1,3-alpha-glucan biosynthetic process + name: regulation of cell wall (1->3)-alpha-glucan biosynthetic process - def: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of 1,3-alpha-glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds, found in the walls of cells. + def: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells. + synonym: "regulation of cell wall 1,3-alpha-glucan biosynthetic process" EXACT [GOC:mah] GO:0070609 : regulation of fungal-type cell wall (1->3)-alpha-glucan metabolic process - name: regulation of fungal-type cell wall 1,3-alpha-glucan metabolic process + name: regulation of fungal-type cell wall (1->3)-alpha-glucan metabolic process - def: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving alpha-1,3 glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds, found in the walls of ascospores. + def: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores. + synonym: "regulation of fungal-type cell wall 1,3-alpha-glucan metabolic process" EXACT [GOC:mah] GO:0070610 : regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process - name: regulation of fungal-type cell wall 1,3-alpha-glucan biosynthetic process + name: regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process - def: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of 1,3-alpha-glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores. + def: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores. - synonym: "regulation of fungal type cell wall 1,3-alpha-glucan biosynthetic process" RELATED [GOC:dph, GOC:tb] + synonym: "regulation of fungal type cell wall 1,3-alpha-glucan biosynthetic process" EXACT [GOC:dph, GOC:tb] GO:0070629 : (1->4)-alpha-glucan metabolic process - name: 1,4-alpha-glucan metabolic process + name: (1->4)-alpha-glucan metabolic process - def: The chemical reactions and pathways involving alpha-1,4 glucans, compounds composed of glucose residues linked by 1,4-alpha-D-glucosidic bonds. + def: The chemical reactions and pathways involving (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds. + synonym: "(1->4)-alpha-D-glucan metabolism" EXACT [GOC:mah] + synonym: "1,4-alpha-D-glucan metabolism" EXACT [GOC:mah] GO:0070630 : (1->4)-alpha-glucan biosynthetic process - name: 1,4-alpha-glucan biosynthetic process + name: (1->4)-alpha-glucan biosynthetic process - def: The chemical reactions and pathways resulting in the formation of alpha-1,4 glucans, compounds composed of glucose residues linked by 1,4-alpha-D-glucosidic bonds. + def: The chemical reactions and pathways resulting in the formation of (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds. + synonym: "(1->4)-alpha-D-glucan formation" EXACT [GOC:mah] + synonym: "(1->4)-alpha-D-glucan synthesis" EXACT [GOC:mah] + synonym: "(1->4)-alpha-D-glucan biosynthesis" EXACT [GOC:mah] + synonym: "1,4-alpha-glucan biosynthetic process" EXACT [GOC:mah] + synonym: "(1->4)-alpha-D-glucan anabolism" EXACT [GOC:mah] GO:0070747 : interleukin-35 receptor activity - is_a: GO:0070746 + relationship: has_part GO:0070746 GO:0070780 : dihydrosphingosine-1-phosphate phosphatase activity + xref: Reactome:REACT_113400 "sphinganine 1-phosphate + H2O => sphinganine + orthophosphate, Schizosaccharomyces pombe" + xref: Reactome:REACT_114387 "sphinganine 1-phosphate + H2O => sphinganine + orthophosphate, Saccharomyces cerevisiae" GO:0070892 : lipoteichoic acid receptor activity - is_a: GO:0070891 + relationship: has_part GO:0070891 GO:0070915 : lysophosphatidic acid receptor activity - def: Combining with lysophosphatidic acid to initiate a change in cell activity. + def: Combining with the phospholipid derivative lysophosphatidic acid, and transmitting the signal across the membrane by activating an associated G-protein. + synonym: "LPA receptor activity" EXACT [PMID:15755723] + relationship: has_part GO:0035727 GO:0071344 : diphosphate metabolic process - xref: Reactome:REACT_28188 "Pyrophosphate hydrolysis, Sus scrofa" - xref: Reactome:REACT_99059 "Pyrophosphate hydrolysis, Caenorhabditis elegans" - xref: Reactome:REACT_107476 "Pyrophosphate hydrolysis, Schizosaccharomyces pombe" + xref: Reactome:REACT_114742 "Pyrophosphate hydrolysis, Arabidopsis thaliana" + xref: Reactome:REACT_34239 "Pyrophosphate hydrolysis, Schizosaccharomyces pombe" + xref: Reactome:REACT_113577 "Pyrophosphate hydrolysis, Plasmodium falciparum" + xref: Reactome:REACT_81374 "Pyrophosphate hydrolysis, Caenorhabditis elegans" + xref: Reactome:REACT_112316 "Pyrophosphate hydrolysis, Oryza sativa" + xref: Reactome:REACT_100411 "Pyrophosphate hydrolysis, Sus scrofa" + xref: Reactome:REACT_115179 "Pyrophosphate hydrolysis, Mycobacterium tuberculosis" GO:0071377 : cellular response to glucagon stimulus + xref: Reactome:REACT_113140 "Glucagon signaling in metabolic regulation, Plasmodium falciparum" GO:0071553 : G-protein coupled pyrimidinergic nucleotide receptor activity + relationship: has_part GO:0019103 GO:0071634 : regulation of transforming growth factor beta production - synonym: "regulation of TGFb production" EXACT [GOC:mah] GO:0071635 : negative regulation of transforming growth factor beta production - synonym: "negative regulation of TGFb production" EXACT [GOC:mah] GO:0071636 : positive regulation of transforming growth factor beta production - synonym: "positive regulation of TGFb production" EXACT [GOC:mah] GO:0071898 : regulation of estrogen receptor binding - is_a: GO:0043393 GO:0071969 : fungal-type cell wall (1->3)-beta-D-glucan metabolic process - name: fungal-type cell wall 1,3-beta-D-glucan metabolic process + name: fungal-type cell wall (1->3)-beta-D-glucan metabolic process - def: The chemical reactions and pathways involving 1,3-beta-glucans, compounds composed of glucose residues linked by 1,3-beta-D-glucosidic bonds, found in the walls of ascospores. + def: The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores. - synonym: "fungal-type cell wall 1,3-beta-glucan metabolic process" BROAD [] + synonym: "fungal-type cell wall 1,3-beta-D-glucan metabolic process" EXACT [] GO:0071970 : fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process - name: fungal-type cell wall 1,3-beta-D-glucan biosynthetic process + name: fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process - def: The chemical reactions and pathways resulting in the formation of 1,3-beta-glucans, compounds composed of glucose residues linked by 1,3-beta-D-glucosidic bonds, found in the walls of ascospores. + def: The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores. - synonym: "fungal-type cell wall 1,3-beta-glucan biosynthetic process" BROAD [] + synonym: "fungal-type cell wall 1,3-beta-D-glucan biosynthetic process" EXACT [] GO:0072078 : nephron tubule morphogenesis - relationship: part_of GO:0072028 GO:0072088 : nephron epithelium morphogenesis + relationship: part_of GO:0072028 GO:0090282 : positive regulation of transcription involved in G2/M-phase of mitotic cell cycle + intersection_of: GO:0045893 + intersection_of: part_of GO:0000086 GO:0090334 : regulation of cell wall (1->3)-beta-D-glucan biosynthetic process - name: regulation of cell wall 1,3-beta-D-glucan biosynthetic process + name: regulation of cell wall (1->3)-beta-D-glucan biosynthetic process - def: Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of 1,3-beta-glucans, compounds composed of glucose residues linked by 1,3-beta-D-glucosidic bonds, found in the walls of cells. + def: Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells. + synonym: "regulation of cell wall 1,3-beta-D-glucan biosynthetic process" BROAD [] GO:0097003 : adipokinetic hormone receptor activity + relationship: has_part GO:0055100 + relationship: has_part GO:0097004 GO:2001077 : (1->3),(1->4)-beta-glucan binding - name: beta-1,3-1,4-glucan binding + name: (1->3),(1->4)-beta-glucan binding - def: Interacting selectively and non-covalently with beta-1,3-1,4-glucan. + def: Interacting selectively and non-covalently with (1->3),(1->4)-beta-glucan. + synonym: "(1,3),(1,4)-beta-glucan binding" EXACT [] + synonym: "1->3,1->4-beta-glucan binding" EXACT [] + synonym: "beta-(1,3),(1,4)-glucan binding" EXACT [] + synonym: "beta-(1->3),(1->4)-glucan binding" EXACT [] + synonym: "beta-1,3-1,4-glucan binding" EXACT [] + synonym: "beta-1->3,1->4-glucan binding" EXACT [] GO:2001078 : (1->6)-beta-D-glucan binding - name: beta-1,6-D-glucan binding + name: (1->6)-beta-D-glucan binding - def: Interacting selectively and non-covalently with beta-1,6-D-glucan. + def: Interacting selectively and non-covalently with (1->6)-beta-D-glucan. + synonym: "(1,6)-beta-D-glucan binding" EXACT [] + synonym: "1,6-beta-D-glucan binding" EXACT [] + synonym: "1->6-beta-D-glucan binding" EXACT [] + synonym: "beta-(1,6)-D-glucan binding" EXACT [] + synonym: "beta-(1->6)-D-glucan binding" EXACT [] + synonym: "beta-1,6-D-glucan binding" EXACT [] + synonym: "beta-1->6-D-glucan binding" EXACT [] GO:2001081 : (1->4)-beta-D-galactan binding + synonym: "(1,4)-beta-D-galactan binding" EXACT [] FILE STATS ========== Term counts for the old and new files Ontology Old file New file Change molecular function 9138 9148 +10 (9138 defined) (9148 defined) cellular component 2918 2918 (2918 defined) (2918 defined) biological process 21506 21549 +43 (21506 defined) (21549 defined) Obsolete 1592 1597 +5 (4.5% of total) (4.5% of total) (+0.3%) Totals 33562 33615 +58 (+0.2%) 33562 (100.0%) defined 33615 (100.0%) defined 35154 inc. obs 35212 inc. obs