Gene Ontology: Ontology Comparison Report

Files used:

  • file 1 (old): go-2011-10-22.obo; date: 21:10:2011 10:06; CVS revision: 1.2341
  • file 2 (new): go-2011-10-29.obo; date: 28:10:2011 16:35; CVS revision: 1.2362

New terms

ID name namespace
GO:0036031 recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex biological_process
GO:0038034 signal transduction in absence of ligand biological_process
GO:0038035 G-protein coupled receptor signaling in absence of ligand biological_process
GO:0038036 sphingosine-1-phosphate receptor activity molecular_function
GO:0044358 envenomation resulting in hemorrhagic damage to other organism biological_process
GO:0044359 modulation of molecular function in other organism biological_process
GO:0044360 modulation of voltage-gated potassium channel activity in other organism biological_process
GO:0044361 negative regulation of voltage-gated potassium channel activity in other organism biological_process
GO:0044362 negative regulation of molecular function in other organism biological_process
GO:0044363 modulation of potassium channel activity in other organism biological_process
GO:0044364 disruption of cells of other organism biological_process
GO:0044365 envenomation resulting in modulation of platelet aggregation in other organism biological_process
GO:0044366 feeding on or from other organism biological_process
GO:0044367 feeding from tissue of other organism biological_process
GO:0044368 feeding from vascular tissue of another organism biological_process
GO:0044369 feeding on blood of other organism biological_process
GO:0044370 injection of substance into other organism during feeding on blood of other organism biological_process
GO:0044371 feeding from phloem of other organism biological_process
GO:0044372 feeding from xylem of other organism biological_process
GO:0052810 1-phosphatidylinositol-5-kinase activity molecular_function
GO:0052811 1-phosphatidylinositol-3-phosphate 4-kinase activity molecular_function
GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity molecular_function
GO:0052813 phosphatidylinositol bisphosphate kinase activity molecular_function
GO:0052814 medium-chain-aldehyde dehydrogenase activity molecular_function
GO:0052815 medium-chain acyl-CoA hydrolase activity molecular_function
GO:0052816 long-chain acyl-CoA hydrolase activity molecular_function
GO:0052817 very long chain acyl-CoA hydrolase activity molecular_function
GO:0052818 heteroglycan 3-alpha-mannosyltransferase activity molecular_function
GO:0052819 heteroglycan 2-alpha-mannosyltransferase activity molecular_function
GO:0052820 DNA-1,N6-ethenoadenine N-glycosylase activity molecular_function
GO:0052821 DNA-7-methyladenine glycosylase activity molecular_function
GO:0052822 DNA-3-methylguanine glycosylase activity molecular_function
GO:0052823 2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity molecular_function
GO:0052824 dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity molecular_function
GO:0090418 positive regulation of transcription involved in S-phase of mitotic cell cycle biological_process
GO:0090419 negative regulation of transcription involved in G2/M-phase of mitotic cell cycle biological_process
GO:2001148 regulation of dipeptide transmembrane transport biological_process
GO:2001149 negative regulation of dipeptide transmembrane transport biological_process
GO:2001150 positive regulation of dipeptide transmembrane transport biological_process
GO:2001151 regulation of renal water transport biological_process
GO:2001152 negative regulation of renal water transport biological_process
GO:2001153 positive regulation of renal water transport biological_process
GO:2001154 regulation of glucose catabolic process to ethanol biological_process
GO:2001155 negative regulation of glucose catabolic process to ethanol biological_process
GO:2001156 regulation of proline catabolic process to glutamate biological_process
GO:2001157 negative regulation of proline catabolic process to glutamate biological_process
GO:2001158 positive regulation of proline catabolic process to glutamate biological_process
GO:2001159 regulation of CVT pathway biological_process
GO:2001160 regulation of histone H3-K79 methylation biological_process
GO:2001161 negative regulation of histone H3-K79 methylation biological_process
GO:2001162 positive regulation of histone H3-K79 methylation biological_process
GO:2001163 regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues biological_process
GO:2001164 negative regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues biological_process
GO:2001165 positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues biological_process
GO:2001166 regulation of histone H2B ubiquitination biological_process
GO:2001167 negative regulation of histone H2B ubiquitination biological_process
GO:2001168 positive regulation of histone H2B ubiquitination biological_process
GO:2001169 regulation of ATP biosynthetic process biological_process
GO:2001170 negative regulation of ATP biosynthetic process biological_process
GO:2001171 positive regulation of ATP biosynthetic process biological_process
GO:2001172 positive regulation of glucose catabolic process to ethanol biological_process

Obsoletions

ID name namespace
GO:0000826 inositol pyrophosphate synthase activity
Consider: GO:0052746
This term was made obsolete because it is incorrectly defined; 'inositol pyrophosphate' is a inositol derivative to which one (or more) pyrophosphate moieties are attached. 'Inositol pyrophosphate synthase' refers to a class of enzymes that catalyze various different reactions that result in the formation of an IP, so one cannot formulate a general reaction for them.
molecular_function
GO:0004428 inositol or phosphatidylinositol kinase activity
Consider: GO:0016307, GO:0019140, GO:0052742, GO:0052813
This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids.
molecular_function
GO:0004437 inositol or phosphatidylinositol phosphatase activity
Consider: GO:0034593, GO:0034594, GO:0052744, GO:0052745
This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids.
molecular_function
GO:0017120 polyphosphatidylinositol phosphatase activity
Consider: GO:0004438, GO:0034593, GO:0043812
This term was made obsolete because it represents a gene product.
molecular_function
GO:0046853 inositol or phosphatidylinositol phosphorylation
Consider: GO:0046854, GO:0052746
This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids.
biological_process

Term merges

Old ID Old name Merged into Merged term name
GO:0016291acyl-CoA thioesterase activityGO:0047617acyl-CoA hydrolase activity
GO:0019282L-methionine biosynthetic process, direct, from O-acetyl-L-homoserineGO:0003961O-acetylhomoserine aminocarboxypropyltransferase activity
GO:0043868N-acetylaminoadipate kinase activityGO:0043744N2-acetyl-L-aminoadipate kinase activity

Term changes

Changes in term-related data
File 1 (21:10:2011 10:06, 1.2341) File 2 (28:10:2011 16:35, 1.2362)
GO:0000009 : alpha-1,6-mannosyltransferase activity
def
Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,6-linkage.
def
Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->6) linkage.
synonym
"1,6-alpha-mannosyltransferase activity" EXACT []
GO:0000016 : lactase activity
xref
Reactome:REACT_112431 "lactose + H2O => D-glucose + D-galactose, Caenorhabditis elegans"
Reactome:REACT_114967 "lactose + H2O => D-glucose + D-galactose, Drosophila melanogaster"
GO:0000026 : alpha-1,2-mannosyltransferase activity
def
Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,2-linkage.
def
Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->2) linkage.
GO:0000033 : alpha-1,3-mannosyltransferase activity
def
Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,3-linkage.
def
Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->3) linkage.
GO:0000048 : peptidyltransferase activity
xref
Reactome:REACT_88081 "Peptide transfer from P-site tRNA to the A-site tRNA, Saccharomyces cerevisiae"
xref
Reactome:REACT_102632 "Peptide transfer from P-site tRNA to the A-site tRNA, Saccharomyces cerevisiae"
Reactome:REACT_112237 "Peptide transfer from P-site tRNA to the A-site tRNA, Bos taurus"
Reactome:REACT_112282 "Peptide transfer from P-site tRNA to the A-site tRNA, Gallus gallus"
Reactome:REACT_115501 "Peptide transfer from P-site tRNA to the A-site tRNA, Rattus norvegicus"
GO:0000050 : urea cycle
xref
Reactome:REACT_105230 "Urea cycle, Sus scrofa"
xref
Reactome:REACT_90565 "Urea cycle, Sus scrofa"
GO:0000064 : L-ornithine transmembrane transporter activity
xref
Reactome:REACT_89637 "ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic), Bos taurus"
GO:0000075 : cell cycle checkpoint
xref
Reactome:REACT_105449 "Cell Cycle Checkpoints, Sus scrofa"
Reactome:REACT_108200 "Cell Cycle Checkpoints, Dictyostelium discoideum"
xref
Reactome:REACT_31789 "Cell Cycle Checkpoints, Dictyostelium discoideum"
Reactome:REACT_79078 "Cell Cycle Checkpoints, Sus scrofa"
GO:0000080 : G1 phase of mitotic cell cycle
xref
Reactome:REACT_106229 "G1 Phase, Sus scrofa"
xref
Reactome:REACT_78866 "G1 Phase, Sus scrofa"
GO:0000082 : G1/S transition of mitotic cell cycle
xref
Reactome:REACT_92675 "G1/S Transition, Sus scrofa"
xref
Reactome:REACT_85355 "G1/S Transition, Sus scrofa"
GO:0000084 : S phase of mitotic cell cycle
xref
Reactome:REACT_31699 "S Phase, Sus scrofa"
xref
Reactome:REACT_85811 "S Phase, Sus scrofa"
GO:0000085 : G2 phase of mitotic cell cycle
xref
Reactome:REACT_104865 "G2 Phase, Drosophila melanogaster"
GO:0000086 : G2/M transition of mitotic cell cycle
xref
Reactome:REACT_114616 "G2/M Transition, Arabidopsis thaliana"
GO:0000115 : regulation of transcription involved in S phase of mitotic cell cycle
xref
Reactome:REACT_871 "S-specific transcription in mitotic cell cycle, Homo sapiens"
GO:0000116 : regulation of transcription involved in G2-phase of mitotic cell cycle
intersection_of
GO:0006355
part_of GO:0000085
GO:0000117 : regulation of transcription involved in G2/M-phase of mitotic cell cycle
xref
Reactome:REACT_335 "G2/M-specific transcription in mitotic cell cycle, Homo sapiens"
intersection_of
GO:0006355
part_of GO:0000086
GO:0000136 : alpha-1,6-mannosyltransferase complex
def
A large, multiprotein complex with alpha-1,6 mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins.
def
A large, multiprotein complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins.
GO:0000148 : 1,3-beta-D-glucan synthase complex
def
A protein complex that catalyzes the transfer of a glucose group from UDP-glucose to a 1,3-beta-D-glucan chain.
def
A protein complex that catalyzes the transfer of a glucose group from UDP-glucose to a (1->3)-beta-D-glucan chain.
synonym
"(1->3)-beta-glucan synthase complex" EXACT [GOC:tb]
GO:0000149 : SNARE binding
xref
Reactome:REACT_104117 "Release of noradrenaline at the synapse, Danio rerio"
Reactome:REACT_105524 "Release of noradrenaline at the synapse, Xenopus tropicalis"
Reactome:REACT_107235 "Vamp8 associated secretory vesicle to plasma membrane transport, Dictyostelium discoideum"
Reactome:REACT_107850 "release of L-Glutamate at the synapse, Danio rerio"
Reactome:REACT_110325 "Vamp8 associated secretory vesicle to plasma membrane transport, Bos taurus"
Reactome:REACT_110416 "Vamp8 associated secretory vesicle to plasma membrane transport, Arabidopsis thaliana"
Reactome:REACT_28124 "Vamp7 associated Lysosome to Plasma membrane transport, Bos taurus"
Reactome:REACT_28160 "Vamp8 associated secretory vesicle to plasma membrane transport, Oryza sativa"
Reactome:REACT_34098 "Release of acetylcholine at the synapse, Danio rerio"
xref
Reactome:REACT_107235 "Vamp2 associated secretory vesicle to plasma membrane transport, Dictyostelium discoideum"
Reactome:REACT_112169 "Acetylcholine synaptic vesicle docking and priming, Caenorhabditis elegans"
Reactome:REACT_112728 "Release of noradrenaline at the synapse, Caenorhabditis elegans"
Reactome:REACT_113606 "Glutamate synaptic vesicle docking and priming, Caenorhabditis elegans"
Reactome:REACT_113753 "Exocytosis of Insulin, Danio rerio"
Reactome:REACT_114225 "Noradrenalin synaptic vesicle docking and priming, Gallus gallus"
Reactome:REACT_114547 "Noradrenalin synaptic vesicle docking and priming, Caenorhabditis elegans"
Reactome:REACT_115054 "release of L-Glutamate at the synapse, Xenopus tropicalis"
Reactome:REACT_115130 "Acetylcholine synaptic vesicle docking and priming, Gallus gallus"
Reactome:REACT_115353 "Release of acetylcholine at the synapse, Xenopus tropicalis"
Reactome:REACT_92466 "Vamp8 associated secretory vesicle to plasma membrane transport, Bos taurus"
Reactome:REACT_99237 "Vamp7 associated Lysosome to Plasma membrane transport, Bos taurus"
GO:0000165 : MAPKKK cascade
xref
Reactome:REACT_112235 "RAF/MAP kinase cascade, Dictyostelium discoideum"
Reactome:REACT_112942 "RAF/MAP kinase cascade, Arabidopsis thaliana"
Reactome:REACT_113285 "RAF/MAP kinase cascade, Oryza sativa"
GO:0000186 : activation of MAPKK activity
xref
Reactome:REACT_113771 "Prolonged ERK activation events, Arabidopsis thaliana"
Reactome:REACT_114228 "Prolonged ERK activation events, Dictyostelium discoideum"
Reactome:REACT_114817 "Prolonged ERK activation events, Oryza sativa"
GO:0000187 : activation of MAPK activity
xref
Reactome:REACT_106895 "activated TAK1 mediates p38 MAPK activation, Caenorhabditis elegans"
Reactome:REACT_80936 "ERK activation, Caenorhabditis elegans"
Reactome:REACT_93683 "activated TAK1 mediates p38 MAPK activation, Schizosaccharomyces pombe"
Reactome:REACT_96987 "activated TAK1 mediates p38 MAPK activation, Saccharomyces cerevisiae"
xref
Reactome:REACT_101870 "ERK activation, Caenorhabditis elegans"
Reactome:REACT_102664 "activated TAK1 mediates p38 MAPK activation, Caenorhabditis elegans"
Reactome:REACT_112664 "ERK activation, Oryza sativa"
Reactome:REACT_113767 "ERK activation, Dictyostelium discoideum"
Reactome:REACT_114778 "ERK activation, Arabidopsis thaliana"
GO:0000189 : MAPK import into nucleus
xref
Reactome:REACT_47300 "Nuclear translocation of phospho-ERK-2 dimer, Sus scrofa"
Reactome:REACT_98625 "Nuclear translocation of phospho-ERK-1 dimer, Saccharomyces cerevisiae"
xref
Reactome:REACT_113196 "Nuclear translocation of phospho-ERK-1 dimer, Oryza sativa"
Reactome:REACT_114932 "Nuclear translocation of phospho-ERK-1 dimer, Dictyostelium discoideum"
Reactome:REACT_115101 "Nuclear translocation of phospho-ERK-1 dimer, Arabidopsis thaliana"
Reactome:REACT_32259 "Nuclear translocation of phospho-ERK-1 dimer, Saccharomyces cerevisiae"
Reactome:REACT_95119 "Nuclear translocation of phospho-ERK-2 dimer, Sus scrofa"
GO:0000216 : M/G1 transition of mitotic cell cycle
xref
Reactome:REACT_110210 "M/G1 Transition, Caenorhabditis elegans"
Reactome:REACT_94911 "M/G1 Transition, Sus scrofa"
xref
Reactome:REACT_103126 "M/G1 Transition, Sus scrofa"
Reactome:REACT_105126 "M/G1 Transition, Caenorhabditis elegans"
GO:0000225 : N-acetylglucosaminylphosphatidylinositol deacetylase activity
xref
Reactome:REACT_31076 "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate, Sus scrofa"
Reactome:REACT_89207 "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate, Saccharomyces cerevisiae"
xref
Reactome:REACT_114989 "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate, Arabidopsis thaliana"
Reactome:REACT_32276 "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate, Saccharomyces cerevisiae"
Reactome:REACT_98776 "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate, Sus scrofa"
GO:0000236 : mitotic prometaphase
xref
Reactome:REACT_34037 "Mitotic Prometaphase, Caenorhabditis elegans"
xref
Reactome:REACT_114704 "Mitotic Prometaphase, Schizosaccharomyces pombe"
Reactome:REACT_31385 "Mitotic Prometaphase, Caenorhabditis elegans"
GO:0000248 : C-5 sterol desaturase activity
xref
Reactome:REACT_102297 "Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol, Arabidopsis thaliana"
GO:0000250 : lanosterol synthase activity
xref
Reactome:REACT_112890 "Squalene 2,3-epoxide cyclizes, forming lanosterol, Oryza sativa"
Reactome:REACT_114747 "Squalene 2,3-epoxide cyclizes, forming lanosterol, Arabidopsis thaliana"
GO:0000252 : C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
xref
Reactome:REACT_90196 "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one, Bos taurus"
xref
Reactome:REACT_106602 "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one, Bos taurus"
Reactome:REACT_112688 "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one, Mycobacterium tuberculosis"
Reactome:REACT_112771 "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one, Escherichia coli"
Reactome:REACT_112854 "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone), Schizosaccharomyces pombe"
Reactome:REACT_112960 "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone), Saccharomyces cerevisiae"
Reactome:REACT_112995 "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one, Schizosaccharomyces pombe"
Reactome:REACT_113072 "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone), Oryza sativa"
Reactome:REACT_113373 "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one, Dictyostelium discoideum"
Reactome:REACT_113553 "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one, Saccharomyces cerevisiae"
Reactome:REACT_114106 "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one, Oryza sativa"
Reactome:REACT_114356 "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone), Dictyostelium discoideum"
Reactome:REACT_115015 "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one, Arabidopsis thaliana"
Reactome:REACT_115441 "4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone), Arabidopsis thaliana"
GO:0000253 : 3-keto sterol reductase activity
xref
Reactome:REACT_97693 "Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol), Sus scrofa"
xref
Reactome:REACT_82943 "Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol), Sus scrofa"
GO:0000254 : C-4 methylsterol oxidase activity
xref
Reactome:REACT_93636 "4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol, Bos taurus"
xref
Reactome:REACT_112865 "4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol, Xenopus tropicalis"
Reactome:REACT_115505 "4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol, Xenopus tropicalis"
Reactome:REACT_97328 "4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol, Bos taurus"
GO:0000278 : mitotic cell cycle
xref
Reactome:REACT_103627 "Cell Cycle, Mitotic, Sus scrofa"
xref
Reactome:REACT_104035 "Cell Cycle, Mitotic, Sus scrofa"
GO:0000288 : nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
xref
Reactome:REACT_81082 "Deadenylation-dependent mRNA decay, Plasmodium falciparum"
xref
Reactome:REACT_105200 "Deadenylation-dependent mRNA decay, Plasmodium falciparum"
GO:0000289 : nuclear-transcribed mRNA poly(A) tail shortening
xref
Reactome:REACT_111968 "Deadenylation of mRNA, Drosophila melanogaster"
GO:0000295 : adenine nucleotide transmembrane transporter activity
xref
Reactome:REACT_113419 "PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP, Oryza sativa"
GO:0000309 : nicotinamide-nucleotide adenylyltransferase activity
xref
Reactome:REACT_108730 "Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT1], Danio rerio"
xref
Reactome:REACT_112138 "Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT2], Arabidopsis thaliana"
Reactome:REACT_112385 "Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT2], Oryza sativa"
Reactome:REACT_114383 "Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT3], Dictyostelium discoideum"
Reactome:REACT_114560 "Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT2], Schizosaccharomyces pombe"
Reactome:REACT_114828 "Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT2], Saccharomyces cerevisiae"
Reactome:REACT_115028 "Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT1], Dictyostelium discoideum"
GO:0000387 : spliceosomal snRNP assembly
xref
Reactome:REACT_88299 "snRNA Cap hypermethylation, Sus scrofa"
Reactome:REACT_92577 "snRNP:Snurportin complex formation, Sus scrofa"
Reactome:REACT_94555 "snRNP complex assembly, Sus scrofa"
xref
Reactome:REACT_112455 "Loading and methylation of Sm proteins onto SMN Complexes, Xenopus tropicalis"
GO:0000398 : nuclear mRNA splicing, via spliceosome
xref
Reactome:REACT_90009 "mRNA Splicing - Minor Pathway, Dictyostelium discoideum"
xref
Reactome:REACT_112200 "mRNA Splicing - Major Pathway, Arabidopsis thaliana"
Reactome:REACT_114266 "mRNA Splicing - Major Pathway, Oryza sativa"
Reactome:REACT_114738 "mRNA Splicing - Major Pathway, Taeniopygia guttata"
Reactome:REACT_34020 "mRNA Splicing - Minor Pathway, Dictyostelium discoideum"
GO:0000703 : oxidized pyrimidine base lesion DNA N-glycosylase activity
xref
Reactome:REACT_104639 "Cleavage of dihydrouracil by hNTH1 glycosylase, Saccharomyces cerevisiae"
Reactome:REACT_106209 "Cleavage of thymine glycol by hNTH1 glycosylase, Saccharomyces cerevisiae"
Reactome:REACT_108989 "Cleavage of formamidopyrimidine by hNTH1 glycosylase, Saccharomyces cerevisiae"
Reactome:REACT_32746 "Cleavage of formamidopyrimidine by hNTH1 glycosylase, Sus scrofa"
Reactome:REACT_86722 "Cleavage of cytosine glycol by hNTH1 glycosylase, Bos taurus"
Reactome:REACT_99711 "Cleavage of cytosine glycol by hNTH1 glycosylase, Saccharomyces cerevisiae"
xref
Reactome:REACT_103837 "Cleavage of formamidopyrimidine by hNTH1 glycosylase, Saccharomyces cerevisiae"
Reactome:REACT_104266 "Cleavage of thymine glycol by hNTH1 glycosylase, Saccharomyces cerevisiae"
Reactome:REACT_107207 "Cleavage of cytosine glycol by hNTH1 glycosylase, Bos taurus"
Reactome:REACT_78298 "Cleavage of dihydrouracil by hNTH1 glycosylase, Saccharomyces cerevisiae"
Reactome:REACT_78343 "Cleavage of formamidopyrimidine by hNTH1 glycosylase, Sus scrofa"
Reactome:REACT_87055 "Cleavage of cytosine glycol by hNTH1 glycosylase, Saccharomyces cerevisiae"
GO:0000715 : nucleotide-excision repair, DNA damage recognition
xref
Reactome:REACT_112311 "DNA Damage Recognition in GG-NER, Caenorhabditis elegans"
Reactome:REACT_115249 "DNA Damage Recognition in GG-NER, Xenopus tropicalis"
GO:0000716 : transcription-coupled nucleotide-excision repair, DNA damage recognition
xref
Reactome:REACT_34608 "RNA Pol II is blocked by the lesion leading to reduced transcription, Saccharomyces cerevisiae"
xref
Reactome:REACT_103224 "RNA Pol II is blocked by the lesion leading to reduced transcription, Saccharomyces cerevisiae"
GO:0000717 : nucleotide-excision repair, DNA duplex unwinding
xref
Reactome:REACT_113177 "Formation of open bubble structure in DNA by helicases, Caenorhabditis elegans"
GO:0000718 : nucleotide-excision repair, DNA damage removal
xref
Reactome:REACT_86542 "Dual incision reaction in GG-NER, Sus scrofa"
xref
Reactome:REACT_89200 "Dual incision reaction in GG-NER, Sus scrofa"
GO:0000722 : telomere maintenance via recombination
xref
Reactome:REACT_104853 "Formation of the Flap Intermediate on the C-strand, Schizosaccharomyces pombe"
Reactome:REACT_107049 "Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere, Saccharomyces cerevisiae"
Reactome:REACT_110309 "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere, Saccharomyces cerevisiae"
Reactome:REACT_77644 "Telomere C-strand synthesis initiation, Plasmodium falciparum"
Reactome:REACT_78865 "Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere, Dictyostelium discoideum"
Reactome:REACT_81386 "RFC binding displaces Pol Alpha on the C-strand of the telomere, Schizosaccharomyces pombe"
Reactome:REACT_92815 "Telomere C-strand synthesis initiation, Schizosaccharomyces pombe"
Reactome:REACT_96478 "RFC dissociates after sliding clamp formation on the C-strand of the telomere, Plasmodium falciparum"
Reactome:REACT_97374 "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere, Saccharomyces cerevisiae"
xref
Reactome:REACT_103350 "Telomere C-strand synthesis initiation, Schizosaccharomyces pombe"
Reactome:REACT_110741 "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere, Saccharomyces cerevisiae"
Reactome:REACT_77906 "RFC dissociates after sliding clamp formation on the C-strand of the telomere, Plasmodium falciparum"
Reactome:REACT_79977 "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere, Saccharomyces cerevisiae"
Reactome:REACT_81258 "RFC binding displaces Pol Alpha on the C-strand of the telomere, Schizosaccharomyces pombe"
Reactome:REACT_96454 "Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere, Saccharomyces cerevisiae"
Reactome:REACT_97849 "Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere, Dictyostelium discoideum"
Reactome:REACT_98885 "Formation of the Flap Intermediate on the C-strand, Schizosaccharomyces pombe"
Reactome:REACT_99836 "Telomere C-strand synthesis initiation, Plasmodium falciparum"
GO:0000723 : telomere maintenance
xref
Reactome:REACT_104812 "Packaging Of Telomere Ends, Gallus gallus"
xref
Reactome:REACT_115102 "Packaging Of Telomere Ends, Canis familiaris"
Reactome:REACT_115503 "Packaging Of Telomere Ends, Danio rerio"
GO:0000724 : double-strand break repair via homologous recombination
xref
Reactome:REACT_30961 "Homologous Recombination Repair, Schizosaccharomyces pombe"
xref
Reactome:REACT_80576 "Homologous Recombination Repair, Schizosaccharomyces pombe"
GO:0000730 : DNA recombinase assembly
xref
Reactome:REACT_99307 "Assembly of the RAD51-ssDNA nucleoprotein complex, Sus scrofa"
xref
Reactome:REACT_79561 "Assembly of the RAD51-ssDNA nucleoprotein complex, Sus scrofa"
GO:0000826 : inositol pyrophosphate synthase activity
def
Catalysis of the phosphorylation of inositol phosphates which possess diphosphate bonds.
is_a
GO:0004428
GO:0016776
def
OBSOLETE. Catalysis of the phosphorylation of inositol phosphates which possess diphosphate bonds.
comment
This term was made obsolete because it is incorrectly defined; 'inositol pyrophosphate' is a inositol derivative to which one (or more) pyrophosphate moieties are attached. 'Inositol pyrophosphate synthase' refers to a class of enzymes that catalyze various different reactions that result in the formation of an IP, so one cannot formulate a general reaction for them.
is_obsolete
true
consider
GO:0052746
GO:0000827 : inositol 1,3,4,5,6-pentakisphosphate kinase activity
is_a
GO:0000826
is_a
GO:0016776
GO:0000828 : inositol hexakisphosphate kinase activity
is_a
GO:0000826
is_a
GO:0016776
GO:0000829 : inositol heptakisphosphate kinase activity
is_a
GO:0000826
is_a
GO:0016776
GO:0001504 : neurotransmitter uptake
xref
Reactome:REACT_34341 "Neurotransmitter uptake and Metabolism In Glial Cells, Sus scrofa"
xref
Reactome:REACT_114027 "Neurotransmitter uptake and Metabolism In Glial Cells, Staphylococcus aureus N315"
Reactome:REACT_89424 "Neurotransmitter uptake and Metabolism In Glial Cells, Sus scrofa"
GO:0001532 : interleukin-21 receptor activity
is_a
GO:0019977
relationship
has_part GO:0019977
GO:0001572 : lactosylceramide biosynthetic process
def
The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal beta(1,4)Glc beta(1,1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides.
def
The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides.
GO:0001575 : globoside metabolic process
def
The chemical reactions and pathways involving globosides, globotetraosylceramides, ceramides containing a core structure of GalNAc-beta-(1,3)-Gal-alpha(1,4)Glc(I). Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes.
def
The chemical reactions and pathways involving globosides, globotetraosylceramides, ceramides containing a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I). Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes.
GO:0001576 : globoside biosynthetic process
def
The chemical reactions and pathways resulting in the formation of a ceramide with a core structure of GalNAc-beta-(1,3)-Gal-alpha(1,4)Glc(I).
def
The chemical reactions and pathways resulting in the formation of a ceramide with a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I).
GO:0001607 : neuromedin U receptor activity
is_a
GO:0042924
relationship
has_part GO:0042924
GO:0001614 : purinergic nucleotide receptor activity
relationship
has_part GO:0017076
GO:0001621 : ADP receptor activity
relationship
has_part GO:0043531
GO:0001646 : cAMP receptor activity
is_a
GO:0030552
relationship
has_part GO:0030552
GO:0001653 : peptide receptor activity
is_a
GO:0042277
relationship
has_part GO:0042277
GO:0001665 : alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity
def
Catalysis of the reaction: CMP-N-acetylneuraminate + glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein = CMP + glycano-(2,6-alpha-N-acetylneuraminyl)-(N-acetyl-D-galactosaminyl)-glycoprotein.
def
Catalysis of the reaction: CMP-N-acetylneuraminate + glycano-(1->3)-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein = CMP + glycano-[(2->6)-alpha-N-acetylneuraminyl]-(N-acetyl-D-galactosaminyl)-glycoprotein.
GO:0001734 : mRNA (N6-adenosine)-methyltransferase activity
xref
Reactome:REACT_85125 "Internal Methylation of mRNA, Saccharomyces cerevisiae"
xref
Reactome:REACT_85371 "Internal Methylation of mRNA, Saccharomyces cerevisiae"
GO:0001792 : polymeric immunoglobulin receptor activity
is_a
GO:0001790
relationship
has_part GO:0001790
GO:0001793 : IgM receptor activity
is_a
GO:0001791
relationship
has_part GO:0001791
GO:0001844 : protein insertion into mitochondrial membrane involved in induction of apoptosis
xref
Reactome:REACT_93779 "Translocation of PUMA protein to mitochondria, Canis familiaris"
xref
Reactome:REACT_112264 "Translocation of activated BAD protein to mitochondria, Xenopus tropicalis"
Reactome:REACT_112484 "Translocation of NOXA to mitochondria, Mus musculus"
Reactome:REACT_112773 "Translocation of NOXA to mitochondria, Rattus norvegicus"
Reactome:REACT_113120 "Translocation of BIM to mitochondria, Xenopus tropicalis"
Reactome:REACT_113968 "Translocation of NOXA to mitochondria, Sus scrofa"
Reactome:REACT_115488 "Translocation of NOXA to mitochondria, Canis familiaris"
GO:0001847 : opsonin receptor activity
is_a
GO:0001846
relationship
has_part GO:0001846
GO:0001857 : complement component C1q receptor activity
is_a
GO:0001849
relationship
has_part GO:0001849
GO:0001858 : complement component iC3b receptor activity
is_a
GO:0001852
relationship
has_part GO:0001852
GO:0001859 : complement component C3dg receptor activity
relationship
has_part GO:0001853
GO:0001860 : complement component C3d receptor activity
relationship
has_part GO:0001854
GO:0001861 : complement component C4b receptor activity
is_a
GO:0001855
relationship
has_part GO:0001855
GO:0001863 : collectin receptor activity
relationship
has_part GO:0001862
GO:0001867 : complement activation, lectin pathway
xref
Reactome:REACT_101763 "Lectin pathway of complement activation, Danio rerio"
xref
Reactome:REACT_114752 "Lectin pathway of complement activation, Canis familiaris"
GO:0001872 : (1->3)-beta-D-glucan binding
name
1,3-beta-D-glucan binding
def
Interacting selectively and non-covalently with 1,3-beta-D-glucans.
name
(1->3)-beta-D-glucan binding
def
Interacting selectively and non-covalently with (1->3)-beta-D-glucans.
synonym
"1,3-beta-D-glucan binding" EXACT []
GO:0001873 : polysaccharide receptor activity
is_a
GO:0030247
relationship
has_part GO:0030247
GO:0001874 : (1->3)-beta-D-glucan receptor activity
name
1,3-beta-D-glucan receptor activity
def
Combining with 1,3-beta-D glucans to initiate a change in cell activity.
synonym
"(1->3)-beta-D-glucan receptor" EXACT []
is_a
GO:0001872
name
(1->3)-beta-D-glucan receptor activity
def
Combining with (1->3)-beta-D-glucans to initiate a change in cell activity.
synonym
"(1,3)-beta-D-glucan receptor activity" EXACT []
"1,3-beta-D-glucan receptor activity" EXACT []
"beta-1,3-D-glucan receptor activity" EXACT []
relationship
has_part GO:0001872
GO:0001875 : lipopolysaccharide receptor activity
is_a
GO:0001530
relationship
has_part GO:0001530
GO:0001877 : lipoarabinomannan receptor activity
is_a
GO:0001876
relationship
has_part GO:0001876
GO:0001888 : glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
def
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1,3)-beta-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-(1,3)-beta-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-D-xylosyl-proteoglycan.
def
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan.
synonym
"UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1,3)-beta-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-D-xylosyl-proteoglycan 4IV-alpha-N-acetyl-D-glucosaminyltransferase activity" EXACT [EC:2.4.1.223]
GO:0001962 : alpha-1,3-galactosyltransferase activity
def
Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-1,3-linkage.
def
Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-(1->3) linkage.
GO:0002114 : interleukin-33 receptor activity
is_a
GO:0002113
relationship
has_part GO:0002113
GO:0002120 : predatory behavior
name
predatory aggressive behavior
name
predatory behavior
synonym
"predatory aggressive behavior" EXACT []
is_a
GO:0044366
GO:0002218 : activation of innate immune response
xref
Reactome:REACT_102126 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Xenopus tropicalis"
Reactome:REACT_105549 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Gallus gallus"
Reactome:REACT_109121 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Mus musculus"
Reactome:REACT_75913 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Homo sapiens"
Reactome:REACT_85368 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Rattus norvegicus"
Reactome:REACT_91372 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Danio rerio"
Reactome:REACT_95496 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Bos taurus"
Reactome:REACT_95597 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Taeniopygia guttata"
Reactome:REACT_97582 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Canis familiaris"
Reactome:REACT_99740 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Sus scrofa"
GO:0002224 : toll-like receptor signaling pathway
xref
Reactome:REACT_8006 "Toll Like Receptor TLR6:TLR2 Cascade, Chlamydia trachomatis"
xref
Reactome:REACT_8006 "Toll Like Receptor TLR6:TLR2 Cascade, Homo sapiens"
GO:0002474 : antigen processing and presentation of peptide antigen via MHC class I
xref
Reactome:REACT_114442 "Class I MHC mediated antigen processing & presentation, Xenopus tropicalis"
GO:0002479 : antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
xref
Reactome:REACT_111056 "Cross-presentation of soluble exogenous antigens (endosomes), Homo sapiens"
Reactome:REACT_111174 "Cross-presentation of particulate exogenous antigens (phagosomes), Homo sapiens"
Reactome:REACT_111178 "ER-Phagosome pathway, Homo sapiens"
GO:0002480 : antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
xref
Reactome:REACT_111168 "Endosomal/Vacuolar pathway, Homo sapiens"
GO:0002576 : platelet degranulation
xref
Reactome:REACT_86087 "Platelet degranulation, Escherichia coli"
GO:0002755 : MyD88-dependent toll-like receptor signaling pathway
xref
Reactome:REACT_29988 "MyD88 cascade initiated on plasma membrane, Dictyostelium discoideum"
Reactome:REACT_86913 "MyD88:Mal cascade initiated on plasma membrane, Caenorhabditis elegans"
Reactome:REACT_95157 "MyD88 cascade initiated on plasma membrane, Sus scrofa"
xref
Reactome:REACT_106952 "MyD88 cascade initiated on plasma membrane, Sus scrofa"
Reactome:REACT_110031 "MyD88 cascade initiated on plasma membrane, Dictyostelium discoideum"
Reactome:REACT_32510 "MyD88:Mal cascade initiated on plasma membrane, Caenorhabditis elegans"
GO:0002756 : MyD88-independent toll-like receptor signaling pathway
xref
Reactome:REACT_102363 "TRAF6 Mediated Induction of proinflammatory cytokines, Caenorhabditis elegans"
xref
Reactome:REACT_106039 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Mus musculus"
Reactome:REACT_110980 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Danio rerio"
Reactome:REACT_114143 "Viral dsRNA:TLR3:TRIF Complex Activates RIP1, Drosophila melanogaster"
Reactome:REACT_25148 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Homo sapiens"
Reactome:REACT_79777 "TRAF6 Mediated Induction of proinflammatory cytokines, Caenorhabditis elegans"
Reactome:REACT_85389 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Rattus norvegicus"
Reactome:REACT_89370 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Xenopus tropicalis"
Reactome:REACT_92796 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Taeniopygia guttata"
Reactome:REACT_96392 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Bos taurus"
Reactome:REACT_97209 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Gallus gallus"
Reactome:REACT_98583 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Sus scrofa"
Reactome:REACT_99202 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Canis familiaris"
GO:0003684 : damaged DNA binding
xref
Reactome:REACT_101374 "Oxidative demethylation of 1-EtA damaged DNA By ABH3, Arabidopsis thaliana"
Reactome:REACT_103614 "Stalling of DNA replication fork and RPA binding, Taeniopygia guttata"
Reactome:REACT_105835 "Stalling of DNA replication fork and RPA binding, Gallus gallus"
Reactome:REACT_109137 "Stalling of DNA replication fork and RPA binding, Rattus norvegicus"
Reactome:REACT_28777 "Oxidative demethylation of 1-EtA damaged DNA By ABH3, Oryza sativa"
Reactome:REACT_6936 "Stalling of DNA replication fork and RPA binding, Homo sapiens"
Reactome:REACT_77532 "Stalling of DNA replication fork and RPA binding, Canis familiaris"
Reactome:REACT_85779 "Oxidative demethylation of 1-MeA damaged DNA By ABH3, Oryza sativa"
Reactome:REACT_86410 "Stalling of DNA replication fork and RPA binding, Mus musculus"
Reactome:REACT_90512 "Stalling of DNA replication fork and RPA binding, Bos taurus"
Reactome:REACT_92706 "Stalling of DNA replication fork and RPA binding, Danio rerio"
Reactome:REACT_94983 "Stalling of DNA replication fork and RPA binding, Xenopus tropicalis"
Reactome:REACT_95130 "Oxidative demethylation of 1-MeA damaged DNA By ABH3, Arabidopsis thaliana"
Reactome:REACT_96445 "Oxidative demethylation of 3-MeC damaged DNA By ABH3, Oryza sativa"
Reactome:REACT_96895 "Oxidative demethylation of 3-MeC damaged DNA By ABH3, Arabidopsis thaliana"
xref
Reactome:REACT_113582 "Oxidative demethylation of 3-MeC damaged DNA By ABH2, Arabidopsis thaliana"
Reactome:REACT_113713 "Oxidative demethylation of 1-EtA damaged DNA By ABH2, Arabidopsis thaliana"
Reactome:REACT_113838 "Oxidative demethylation of 1-EtA damaged DNA By ABH2, Oryza sativa"
Reactome:REACT_114851 "Oxidative demethylation of 3-MeC damaged DNA By ABH2, Oryza sativa"
Reactome:REACT_85779 "Oxidative demethylation of 1-MeA damaged DNA By ABH2, Oryza sativa"
Reactome:REACT_95130 "Oxidative demethylation of 1-MeA damaged DNA By ABH2, Arabidopsis thaliana"
GO:0003689 : DNA clamp loader activity
xref
Reactome:REACT_85266 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Dictyostelium discoideum"
xref
Reactome:REACT_113703 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Gallus gallus"
Reactome:REACT_33572 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Dictyostelium discoideum"
GO:0003708 : retinoic acid receptor activity
relationship
has_part GO:0001972
GO:0003720 : telomerase activity
xref
Reactome:REACT_101043 "Elongation Of The Telomeric Chromosome End, Saccharomyces cerevisiae"
Reactome:REACT_30302 "Elongation Of The Telomeric Chromosome End, Dictyostelium discoideum"
Reactome:REACT_32224 "Elongation of Extended Telomeric Chromosome End, Dictyostelium discoideum"
Reactome:REACT_77982 "Elongation Of The Telomeric Chromosome End, Sus scrofa"
Reactome:REACT_84958 "Elongation of Extended Telomeric Chromosome End, Saccharomyces cerevisiae"
xref
Reactome:REACT_104705 "Elongation of Extended Telomeric Chromosome End, Saccharomyces cerevisiae"
Reactome:REACT_113385 "Elongation Of The Telomeric Chromosome End, Xenopus tropicalis"
Reactome:REACT_114466 "Elongation of Extended Telomeric Chromosome End, Xenopus tropicalis"
Reactome:REACT_30494 "Elongation Of The Telomeric Chromosome End, Sus scrofa"
Reactome:REACT_31549 "Elongation Of The Telomeric Chromosome End, Saccharomyces cerevisiae"
GO:0003724 : RNA helicase activity
xref
Reactome:REACT_93046 "Cap-bound mRNA is activated by helicases, Rattus norvegicus"
xref
Reactome:REACT_112817 "Cap-bound mRNA is activated by helicases, Schizosaccharomyces pombe"
GO:0003726 : double-stranded RNA adenosine deaminase activity
xref
Reactome:REACT_112019 "Deamination at C6 position of adenosine in Editosome (ADAR1), Oryza sativa"
Reactome:REACT_112024 "Deamination at C6 position of adenosine in Editosome (ADAR1), Saccharomyces cerevisiae"
Reactome:REACT_113770 "Deamination at C6 position of adenosine in Editosome (ADAR1), Caenorhabditis elegans"
Reactome:REACT_114900 "Deamination at C6 position of adenosine in Editosome (ADAR1), Arabidopsis thaliana"
Reactome:REACT_115470 "Deamination at C6 position of adenosine in Editosome (ADAR1), Schizosaccharomyces pombe"
GO:0003743 : translation initiation factor activity
xref
Reactome:REACT_112013 "Start codon recognition, Gallus gallus"
Reactome:REACT_114676 "Ribosomal scanning, Gallus gallus"
Reactome:REACT_115071 "Ribosomal scanning, Rattus norvegicus"
Reactome:REACT_115079 "Start codon recognition, Rattus norvegicus"
Reactome:REACT_115451 "Start codon recognition, Bos taurus"
GO:0003777 : microtubule motor activity
xref
Reactome:REACT_83443 "Translocation of Insulin Secretory Granules to Cell Cortex, Gallus gallus"
Reactome:REACT_88648 "Axonal transport of NGF:Trk complexes, Rattus norvegicus"
xref
Reactome:REACT_113466 "Axonal transport of NGF:Trk complexes, Caenorhabditis elegans"
Reactome:REACT_115371 "Translocation of Insulin Secretory Granules to Cell Cortex, Gallus gallus"
GO:0003796 : lysozyme activity
def
Catalysis of the hydrolysis of the 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.
def
Catalysis of the hydrolysis of the beta-(1->4) linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.
GO:0003810 : protein-glutamine gamma-glutamyltransferase activity
xref
Reactome:REACT_112106 "fibrin multimer -> fibrin multimer, crosslinked + NH4+, Drosophila melanogaster"
Reactome:REACT_112367 "fibrin multimer -> fibrin multimer, crosslinked + NH4+, Sus scrofa"
Reactome:REACT_112902 "fibrin multimer -> fibrin multimer, crosslinked + NH4+, Xenopus tropicalis"
GO:0003826 : alpha-ketoacid dehydrogenase activity
xref
Reactome:REACT_113399 "a-ketoisocaproate, a-keto b-methylvalerate, or a-ketoisovalerate + CoA + NAD+ => isovaleryl-CoA, a-methylbutyryl-CoA, or isobuyryl-CoA + CO2 + NADH + H+, Mycobacterium tuberculosis"
GO:0003828 : alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity
def
Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-2,8-alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-R.
synonym
"CMP-NeuAc:LM1(alpha2-8) sialyltranferase activity" EXACT [EC:2.4.99.8]
def
Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R.
synonym
"CMP-NeuAc:LM1 alpha-(2->8)-sialyltranferase activity" EXACT [EC:2.4.99.8]
"CMP-NeuAc:LM1(alpha-2,8) sialyltranferase activity" EXACT [EC:2.4.99.8]
GO:0003829 : beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity
def
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R = UDP + beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R.
def
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R = UDP + beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-D-galactosaminyl-R.
synonym
"uridine diphosphoacetylglucosamine-mucin beta-(1,6)-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.102]
GO:0003831 : beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
def
Catalysis of the reaction: UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminylglycopeptide.
synonym
"beta-N-acetyl-beta1-4-galactosyltransferase activity" EXACT [EC:2.4.1.38]
def
Catalysis of the reaction: UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide.
synonym
"beta-N-acetyl-beta-(1,4)-galactosyltransferase activity" EXACT [EC:2.4.1.38]
"beta-N-acetyl-beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.38]
GO:0003835 : beta-galactoside alpha-2,6-sialyltransferase activity
def
Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-acetyl-beta-D-glucosamine = CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine.
def
Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-acetyl-beta-D-glucosamine = CMP + alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine.
GO:0003836 : beta-galactoside (CMP) alpha-2,3-sialyltransferase activity
def
Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R.
def
Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R = CMP + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R.
GO:0003837 : beta-ureidopropionase activity
xref
Reactome:REACT_112730 "beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2, Schizosaccharomyces pombe"
Reactome:REACT_115012 "beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2, Schizosaccharomyces pombe"
GO:0003840 : gamma-glutamyltransferase activity
xref
Reactome:REACT_28642 "Cleavage of the gamma-glutamyl bond of LTC4 forms LTD4, Drosophila melanogaster"
xref
Reactome:REACT_114722 "Cleavage of the gamma-glutamyl bond of LTC4 forms LTD4, Caenorhabditis elegans"
GO:0003841 : 1-acylglycerol-3-phosphate O-acyltransferase activity
xref
Reactome:REACT_113184 "1-acyl-glycerol 3-phosphate + acyl-CoA => 1,2-diacyl-glycerol 3-phosphate + CoASH, Dictyostelium discoideum"
Reactome:REACT_113260 "1-acyl-glycerol 3-phosphate + acyl-CoA => 1,2-diacyl-glycerol 3-phosphate + CoASH, Arabidopsis thaliana"
Reactome:REACT_115377 "1-acyl-glycerol 3-phosphate + acyl-CoA => 1,2-diacyl-glycerol 3-phosphate + CoASH, Caenorhabditis elegans"
GO:0003843 : 1,3-beta-D-glucan synthase activity
def
Catalysis of the reaction: UDP-glucose + 1,3-beta-D-glucosyl(n) = UDP + 1,3-beta-D-glucosyl(n+1).
def
Catalysis of the reaction: UDP-glucose + [(1->3)-beta-D-glucosyl](n) = UDP + [(1->3)-beta-D-glucosyl](n+1).
GO:0003844 : 1,4-alpha-glucan branching enzyme activity
def
Catalysis of the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxyl group in a similar glucan chain.
def
Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxyl group in a similar glucan chain.
xref
Reactome:REACT_115406 "poly((1,4)-alpha-D-glucosyl) glycogenin => glycogen-glycogenin, Arabidopsis thaliana"
GO:0003845 : 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity
xref
Reactome:REACT_96314 "Oxidation of cortisol to yield cortisone, Mycobacterium tuberculosis"
xref
Reactome:REACT_114165 "Oxidation of cortisol to yield cortisone, Plasmodium falciparum"
GO:0003854 : 3-beta-hydroxy-delta5-steroid dehydrogenase activity
xref
Reactome:REACT_111989 "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol, Mycobacterium tuberculosis"
Reactome:REACT_112248 "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione, Escherichia coli"
Reactome:REACT_113096 "Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione, Mycobacterium tuberculosis"
Reactome:REACT_113257 "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one, Escherichia coli"
Reactome:REACT_113772 "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one, Escherichia coli"
Reactome:REACT_114424 "17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol, Escherichia coli"
Reactome:REACT_114777 "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one, Mycobacterium tuberculosis"
Reactome:REACT_114921 "Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one, Mycobacterium tuberculosis"
Reactome:REACT_115275 "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one, Escherichia coli"
Reactome:REACT_115303 "Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one, Mycobacterium tuberculosis"
GO:0003857 : 3-hydroxyacyl-CoA dehydrogenase activity
xref
Reactome:REACT_100712 "(S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H, Caenorhabditis elegans"
Reactome:REACT_104037 "(S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H, Caenorhabditis elegans"
Reactome:REACT_106331 "(S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H, Caenorhabditis elegans"
Reactome:REACT_106409 "alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+, Caenorhabditis elegans"
Reactome:REACT_106559 "(24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA, Mycobacterium tuberculosis"
Reactome:REACT_106616 "(24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA, Mycobacterium tuberculosis"
Reactome:REACT_110368 "3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+, Mycobacterium tuberculosis"
Reactome:REACT_28990 "(S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H, Escherichia coli"
Reactome:REACT_51199 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Bos taurus"
Reactome:REACT_90995 "(24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA, Saccharomyces cerevisiae"
Reactome:REACT_98365 "(S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H, Escherichia coli"
xref
Reactome:REACT_101468 "(S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H, Caenorhabditis elegans"
Reactome:REACT_103002 "alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+, Caenorhabditis elegans"
Reactome:REACT_110947 "(S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H, Caenorhabditis elegans"
Reactome:REACT_112490 "(S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H, Staphylococcus aureus N315"
Reactome:REACT_113301 "(S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H, Staphylococcus aureus N315"
Reactome:REACT_113705 "(S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H, Staphylococcus aureus N315"
Reactome:REACT_115146 "(S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H, Staphylococcus aureus N315"
Reactome:REACT_115227 "(S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H, Staphylococcus aureus N315"
Reactome:REACT_81715 "(24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA, Saccharomyces cerevisiae"
Reactome:REACT_99158 "(S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H, Caenorhabditis elegans"
Reactome:REACT_99776 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Bos taurus"
GO:0003858 : 3-hydroxybutyrate dehydrogenase activity
xref
Reactome:REACT_100598 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Taeniopygia guttata"
Reactome:REACT_100701 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Gallus gallus"
Reactome:REACT_101032 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Arabidopsis thaliana"
Reactome:REACT_103337 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Saccharomyces cerevisiae"
Reactome:REACT_103885 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Canis familiaris"
Reactome:REACT_108608 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Danio rerio"
Reactome:REACT_108694 "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+, Mycobacterium tuberculosis"
Reactome:REACT_31121 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Bos taurus"
Reactome:REACT_32549 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Oryza sativa"
Reactome:REACT_32582 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Dictyostelium discoideum"
Reactome:REACT_32814 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Rattus norvegicus"
Reactome:REACT_34160 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Drosophila melanogaster"
Reactome:REACT_631 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Homo sapiens"
Reactome:REACT_78212 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Sus scrofa"
Reactome:REACT_81074 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Mus musculus"
Reactome:REACT_81394 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Mycobacterium tuberculosis"
Reactome:REACT_82478 "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+, Arabidopsis thaliana"
Reactome:REACT_84490 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Schizosaccharomyces pombe"
Reactome:REACT_85059 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Xenopus tropicalis"
Reactome:REACT_86958 "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+, Saccharomyces cerevisiae"
Reactome:REACT_89789 "Reduction of Acetoacetate to beta-Hydroxybutyrate, Escherichia coli"
Reactome:REACT_91128 "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+, Dictyostelium discoideum"
Reactome:REACT_92932 "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+, Oryza sativa"
Reactome:REACT_95531 "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+, Drosophila melanogaster"
Reactome:REACT_97350 "D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+, Schizosaccharomyces pombe"
xref
Reactome:REACT_100598 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Taeniopygia guttata"
Reactome:REACT_100701 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Gallus gallus"
Reactome:REACT_103885 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Canis familiaris"
Reactome:REACT_104408 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Sus scrofa"
Reactome:REACT_108608 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Danio rerio"
Reactome:REACT_31121 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Bos taurus"
Reactome:REACT_32814 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Rattus norvegicus"
Reactome:REACT_631 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Homo sapiens"
Reactome:REACT_81074 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Mus musculus"
Reactome:REACT_85059 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Xenopus tropicalis"
Reactome:REACT_89789 "acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+, Escherichia coli"
GO:0003860 : 3-hydroxyisobutyryl-CoA hydrolase activity
xref
Reactome:REACT_115031 "beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA, Arabidopsis thaliana"
GO:0003870 : 5-aminolevulinate synthase activity
xref
Reactome:REACT_103620 "Succinyl CoA and glycine condense to form 5-aminolevulinate (ALA), Schizosaccharomyces pombe"
xref
Reactome:REACT_98622 "Succinyl CoA and glycine condense to form 5-aminolevulinate (ALA), Schizosaccharomyces pombe"
GO:0003872 : 6-phosphofructokinase activity
xref
Reactome:REACT_93423 "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP, Dictyostelium discoideum"
xref
Reactome:REACT_112049 "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP, Oryza sativa"
Reactome:REACT_114580 "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP, Arabidopsis thaliana"
Reactome:REACT_96419 "D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP, Dictyostelium discoideum"
GO:0003874 : 6-pyruvoyltetrahydropterin synthase activity
xref
Reactome:REACT_111082 "DHNTP is dephosphorylated by PTPS to PTHP, Homo sapiens"
GO:0003876 : AMP deaminase activity
xref
Reactome:REACT_85426 "AMP + H2O => IMP + NH3 [AMPD], Schizosaccharomyces pombe"
GO:0003883 : CTP synthase activity
xref
Reactome:REACT_33487 "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2], Sus scrofa"
xref
Reactome:REACT_98846 "UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2], Sus scrofa"
GO:0003884 : D-amino-acid oxidase activity
xref
Reactome:REACT_113962 "glycine + O2 => glyoxylate + H2O2 + NH4+, Schizosaccharomyces pombe"
Reactome:REACT_114219 "glycine + O2 => glyoxylate + H2O2 + NH4+, Drosophila melanogaster"
Reactome:REACT_115360 "glycine + O2 => glyoxylate + H2O2 + NH4+, Mycobacterium tuberculosis"
Reactome:REACT_115482 "glycine + O2 => glyoxylate + H2O2 + NH4+, Caenorhabditis elegans"
GO:0003886 : DNA (cytosine-5-)-methyltransferase activity
synonym
"DNA cytosine c5 methylase activity" EXACT [EC:2.1.1.37]
GO:0003887 : DNA-directed DNA polymerase activity
xref
Reactome:REACT_103629 "Misinsertion of bases opposite to the lesion by HREV1, Saccharomyces cerevisiae"
Reactome:REACT_107698 "Insertion of correct bases opposite to the lesion by Pol eta, Saccharomyces cerevisiae"
Reactome:REACT_110309 "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere, Saccharomyces cerevisiae"
Reactome:REACT_76968 "POL Beta mediated incorporation of the first replacement nucleotide, Bos taurus"
Reactome:REACT_78710 "Elongation by HREV1 protein, Saccharomyces cerevisiae"
Reactome:REACT_79973 "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin, Dictyostelium discoideum"
Reactome:REACT_80652 "Elongation by Pol eta, Saccharomyces cerevisiae"
xref
Reactome:REACT_105070 "Insertion of correct bases opposite to the lesion by Pol eta, Saccharomyces cerevisiae"
Reactome:REACT_112231 "Elongation by Pol zeta complex, Xenopus tropicalis"
Reactome:REACT_112289 "Elongation by Pol zeta complex, Taeniopygia guttata"
Reactome:REACT_112468 "Elongation by Pol zeta complex, Dictyostelium discoideum"
Reactome:REACT_28865 "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin, Dictyostelium discoideum"
Reactome:REACT_79977 "The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere, Saccharomyces cerevisiae"
Reactome:REACT_83674 "Elongation by Pol eta, Saccharomyces cerevisiae"
Reactome:REACT_84407 "Elongation by HREV1 protein, Saccharomyces cerevisiae"
Reactome:REACT_90511 "Misinsertion of bases opposite to the lesion by HREV1, Saccharomyces cerevisiae"
Reactome:REACT_94622 "POL Beta mediated incorporation of the first replacement nucleotide, Bos taurus"
GO:0003899 : DNA-directed RNA polymerase activity
xref
Reactome:REACT_102116 "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Bos taurus"
Reactome:REACT_108565 "Pol II mediated transcription of microRNA genes, Caenorhabditis elegans"
Reactome:REACT_110838 "Addition of the third nucleotide on the nascent transcript, Bos taurus"
Reactome:REACT_29713 "Addition of nucleotides between position +11 and +30, Saccharomyces cerevisiae"
Reactome:REACT_79401 "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Schizosaccharomyces pombe"
Reactome:REACT_80211 "Elongation of pre-rRNA transcript, Bos taurus"
Reactome:REACT_84507 "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin, Dictyostelium discoideum"
Reactome:REACT_88953 "Addition of the third nucleotide on the nascent transcript, Canis familiaris"
Reactome:REACT_97374 "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere, Saccharomyces cerevisiae"
Reactome:REACT_99106 "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Canis familiaris"
xref
Reactome:REACT_109090 "Addition of nucleotides between position +11 and +30, Saccharomyces cerevisiae"
Reactome:REACT_110741 "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere, Saccharomyces cerevisiae"
Reactome:REACT_112737 "Addition of Nucleotides 5 through 9 on the growing Transcript, Gallus gallus"
Reactome:REACT_112968 "Elongation of pre-rRNA transcript, Oryza sativa"
Reactome:REACT_113943 "Elongation of pre-rRNA transcript, Gallus gallus"
Reactome:REACT_28467 "Pol II mediated transcription of microRNA genes, Caenorhabditis elegans"
Reactome:REACT_31554 "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Schizosaccharomyces pombe"
Reactome:REACT_78158 "Elongation of pre-rRNA transcript, Bos taurus"
Reactome:REACT_80464 "The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin, Dictyostelium discoideum"
GO:0003905 : alkylbase DNA N-glycosylase activity
def
Catalysis of the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine. Enzymes with this activity recognize and remove alkylated purines and pyrimidines by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic or apyrimidinic (AP) site.
def
Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site.
GO:0003906 : DNA-(apurinic or apyrimidinic site) lyase activity
xref
Reactome:REACT_86232 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Sus scrofa"
xref
Reactome:REACT_85754 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Sus scrofa"
GO:0003908 : methylated-DNA-[protein]-cysteine S-methyltransferase activity
xref
Reactome:REACT_102469 "MGMT/hAGT mediated DNA Damage Reversal, Escherichia coli"
Reactome:REACT_87264 "MGMT/hAGT mediated DNA Damage Reversal, Sus scrofa"
xref
Reactome:REACT_108289 "MGMT/hAGT mediated DNA Damage Reversal, Sus scrofa"
GO:0003909 : DNA ligase activity
xref
Reactome:REACT_101158 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Saccharomyces cerevisiae"
Reactome:REACT_102434 "Ligation of DNA and formation of Holliday structures following repair synthesis, Caenorhabditis elegans"
Reactome:REACT_80904 "Ligation of DNA at sites of patch replacement, Sus scrofa"
xref
Reactome:REACT_109841 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Saccharomyces cerevisiae"
Reactome:REACT_112118 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Mus musculus"
Reactome:REACT_112246 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Sus scrofa"
Reactome:REACT_113076 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Xenopus tropicalis"
Reactome:REACT_113217 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Gallus gallus"
Reactome:REACT_113661 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Canis familiaris"
Reactome:REACT_113851 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Bos taurus"
Reactome:REACT_114038 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Rattus norvegicus"
Reactome:REACT_114285 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Danio rerio"
Reactome:REACT_114706 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Taeniopygia guttata"
Reactome:REACT_31800 "Ligation of DNA at sites of patch replacement, Sus scrofa"
Reactome:REACT_82930 "Ligation of DNA and formation of Holliday structures following repair synthesis, Caenorhabditis elegans"
GO:0003919 : FMN adenylyltransferase activity
xref
Reactome:REACT_79042 "FMN is futher phosphorylated to FAD, Drosophila melanogaster"
GO:0003921 : GMP synthase activity
xref
Reactome:REACT_114078 "XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate, Xenopus tropicalis"
GO:0003923 : GPI-anchor transamidase activity
xref
Reactome:REACT_78112 "uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide, Bos taurus"
Reactome:REACT_97490 "uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide, Sus scrofa"
xref
Reactome:REACT_113833 "uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide, Xenopus tropicalis"
Reactome:REACT_34799 "uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide, Sus scrofa"
Reactome:REACT_92319 "uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide, Bos taurus"
GO:0003924 : GTPase activity
xref
Reactome:REACT_100393 "Disassembly of COPII coated vesicle, Bos taurus"
Reactome:REACT_104791 "Vesicle Uncoating, Schizosaccharomyces pombe"
Reactome:REACT_105040 "Hydrolysis of eEF1A:GTP, Saccharomyces cerevisiae"
Reactome:REACT_108111 "Hydrolysis of eEF1A:GTP, Oryza sativa"
Reactome:REACT_30005 "Adenylate cyclase increases the GTPase activity of G alpha-olf, Caenorhabditis elegans"
Reactome:REACT_30968 "Adenylate cyclase increases the GTPase activity of G alpha-olf, Dictyostelium discoideum"
Reactome:REACT_31077 "Hydrolysis of eEF1A:GTP, Caenorhabditis elegans"
Reactome:REACT_31604 "G-protein alpha subunit is inactivated, Saccharomyces cerevisiae"
Reactome:REACT_32756 "G-protein alpha subunit is inactivated, Sus scrofa"
Reactome:REACT_39715 "Vesicle Uncoating, Sus scrofa"
Reactome:REACT_63828 "trans-Golgi Network Vesicle Scission, Caenorhabditis elegans"
Reactome:REACT_77877 "Loss of Sar1b GTPase, Caenorhabditis elegans"
Reactome:REACT_80598 "Hydrolysis of eEF1A:GTP, Arabidopsis thaliana"
Reactome:REACT_82856 "G alpha (z) auto-inactivates by hydrolysing GTP to GDP, Caenorhabditis elegans"
Reactome:REACT_84312 "Adenylate cyclase increases the GTPase activity of Gi alpha, Caenorhabditis elegans"
Reactome:REACT_84776 "Loss of Sar1b GTPase, Sus scrofa"
Reactome:REACT_86940 "Disassembly of COPII coated vesicle, Canis familiaris"
Reactome:REACT_87519 "Hydrolysis of eEF1A:GTP, Taeniopygia guttata"
Reactome:REACT_89133 "Adenylaye cyclase increases the GTPase activity of G alpha-olf, Dictyostelium discoideum"
Reactome:REACT_92563 "Vesicle Uncoating, Caenorhabditis elegans"
Reactome:REACT_93472 "Disassembly of COPII coated vesicle, Sus scrofa"
Reactome:REACT_95550 "G alpha (z) auto-inactivates by hydrolysing GTP to GDP, Drosophila melanogaster"
Reactome:REACT_96172 "Loss of Sar1b GTPase, Dictyostelium discoideum"
Reactome:REACT_97130 "Disassembly of COPII coated vesicle, Rattus norvegicus"
Reactome:REACT_97625 "Adenylate cyclase increases the GTPase activity of Gi alpha, Dictyostelium discoideum"
Reactome:REACT_99049 "Hydrolysis of eEF1A:GTP, Xenopus tropicalis"
xref
Reactome:REACT_104739 "Loss of Sar1b GTPase, Dictyostelium discoideum"
Reactome:REACT_105697 "G-protein alpha subunit is inactivated, Saccharomyces cerevisiae"
Reactome:REACT_110931 "G-protein alpha subunit is inactivated, Sus scrofa"
Reactome:REACT_111994 "G alpha (z) auto-inactivates by hydrolysing GTP to GDP, Xenopus tropicalis"
Reactome:REACT_112104 "Endocytosis (internalization) of clathrin-coated vesicle, Sus scrofa"
Reactome:REACT_112254 "Endocytosis (internalization) of clathrin-coated vesicle, Xenopus tropicalis"
Reactome:REACT_112389 "Disassembly of COPII coated vesicle, Gallus gallus"
Reactome:REACT_112587 "trans-Golgi Network Vesicle Scission, Schizosaccharomyces pombe"
Reactome:REACT_112651 "Vesicle Uncoating, Xenopus tropicalis"
Reactome:REACT_112671 "Vesicle Uncoating, Plasmodium falciparum"
Reactome:REACT_113058 "G alpha (s) auto-inactivates by hydrolysing GTP to GDP, Saccharomyces cerevisiae"
Reactome:REACT_113209 "G alpha (z) auto-inactivates by hydrolysing GTP to GDP, Schizosaccharomyces pombe"
Reactome:REACT_113727 "G alpha (q) auto-inactivates by hydrolysing GTP to GDP, Saccharomyces cerevisiae"
Reactome:REACT_113832 "Formation of clathrin coated vesicle, Bos taurus"
Reactome:REACT_113912 "Hydrolysis of eEF1A:GTP, Bos taurus"
Reactome:REACT_113952 "Formation of clathrin coated vesicle, Schizosaccharomyces pombe"
Reactome:REACT_113954 "Endocytosis (internalization) of clathrin-coated vesicle, Schizosaccharomyces pombe"
Reactome:REACT_114148 "G alpha (q) auto-inactivates by hydrolysing GTP to GDP, Schizosaccharomyces pombe"
Reactome:REACT_114153 "Loss of Sar1b GTPase, Xenopus tropicalis"
Reactome:REACT_114188 "Formation of clathrin coated vesicle, Sus scrofa"
Reactome:REACT_114210 "G-protein alpha subunit is inactivated, Schizosaccharomyces pombe"
Reactome:REACT_114331 "trans-Golgi Network Vesicle Scission, Taeniopygia guttata"
Reactome:REACT_114379 "Formation of clathrin coated vesicle, Taeniopygia guttata"
Reactome:REACT_114384 "Hydrolysis of eEF1A:GTP, Gallus gallus"
Reactome:REACT_114532 "Formation of clathrin coated vesicle, Xenopus tropicalis"
Reactome:REACT_114620 "Endocytosis (internalization) of clathrin-coated vesicle, Taeniopygia guttata"
Reactome:REACT_114824 "trans-Golgi Network Lysosomal Vesicle Scission, Taeniopygia guttata"
Reactome:REACT_115229 "G alpha (s) auto-inactivates by hydrolysing GTP to GDP, Schizosaccharomyces pombe"
Reactome:REACT_115324 "Endocytosis (internalization) of clathrin-coated vesicle, Bos taurus"
Reactome:REACT_28065 "Vesicle Uncoating, Sus scrofa"
Reactome:REACT_30707 "trans-Golgi Network Vesicle Scission, Caenorhabditis elegans"
Reactome:REACT_34113 "Vesicle Uncoating, Schizosaccharomyces pombe"
Reactome:REACT_84712 "Hydrolysis of eEF1A:GTP, Saccharomyces cerevisiae"
Reactome:REACT_93305 "Loss of Sar1b GTPase, Sus scrofa"
GO:0003934 : GTP cyclohydrolase I activity
xref
Reactome:REACT_111143 "GCH1 reduces GTP to dihydroneopterin triphosphate, Homo sapiens"
GO:0003937 : IMP cyclohydrolase activity
xref
Reactome:REACT_79931 "FAICAR => IMP + H2O, Caenorhabditis elegans"
xref
Reactome:REACT_101852 "FAICAR => IMP + H2O, Caenorhabditis elegans"
GO:0003945 : N-acetyllactosamine synthase activity
synonym
"beta-N-acetylglucosaminide beta1-4-galactosyltransferase activity" EXACT [EC:2.4.1.90]
"beta1-4-galactosyltransferase activity" EXACT [EC:2.4.1.90]
"beta1-4GalT" RELATED [EC:2.4.1.90]
"N-acetylglucosamine (beta1,4)galactosyltransferase activity" EXACT [EC:2.4.1.90]
"UDP-Gal:N-acetylglucosamine beta1-4-galactosyltransferase activity" EXACT [EC:2.4.1.90]
"UDP-galactose:N-acetylglucosaminide beta1-4-galactosyltransferase activity" EXACT [EC:2.4.1.90]
"UDPgalactose:N-acetylglucosaminyl(beta1-4)galactosyltransferase activity" EXACT [EC:2.4.1.90]
synonym
"beta-(1,4)-galactosyltransferase activity" EXACT [EC:2.4.1.90]
"beta-1,4-GalT" RELATED [EC:2.4.1.90]
"beta-N-acetylglucosaminide beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.90]
"N-acetylglucosamine beta-(1,4)-galactosyltransferase activity" EXACT [EC:2.4.1.90]
"UDP-Gal:N-acetylglucosamine beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.90]
"UDP-galactose:N-acetylglucosaminide beta-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.90]
"UDPgalactose:N-acetylglucosaminyl(beta-1,4)galactosyltransferase activity" EXACT [EC:2.4.1.90]
GO:0003951 : NAD+ kinase activity
xref
Reactome:REACT_109385 "NAD+ is phosphorylated to NADP+, Schizosaccharomyces pombe"
Reactome:REACT_88583 "NAD+ is phosphorylated to NADP+, Staphylococcus aureus N315"
Reactome:REACT_97396 "NAD+ is phosphorylated to NADP+, Saccharomyces cerevisiae"
GO:0003952 : NAD+ synthase (glutamine-hydrolyzing) activity
xref
Reactome:REACT_98752 "Amidation of deamino-NAD+ to NAD+, Dictyostelium discoideum"
xref
Reactome:REACT_112596 "Amidation of deamino-NAD+ to NAD+, Xenopus tropicalis"
Reactome:REACT_84016 "Amidation of deamino-NAD+ to NAD+, Dictyostelium discoideum"
GO:0003961 : O-acetylhomoserine aminocarboxypropyltransferase activity
alt_id
GO:0019282
synonym
"L-methionine anabolism, direct, from O-acetyl-L-homoserine" EXACT [GOC:mah]
"L-methionine biosynthetic process, direct, from O-acetyl-L-homoserine" EXACT []
"L-methionine formation, direct, from O-acetyl-L-homoserine" EXACT [GOC:mah]
"L-methionine synthesis, direct, from O-acetyl-L-homoserine" EXACT [GOC:mah]
"methionine biosynthetic process, direct, from O-acetyl-L-homoserine" EXACT [GOC:mah]
relationship
part_of GO:0071266
GO:0003978 : UDP-glucose 4-epimerase activity
xref
Reactome:REACT_29100 "UDP-galactose <=> UDP-glucose, Dictyostelium discoideum"
Reactome:REACT_31187 "UDP-galactose <=> UDP-glucose, Mycobacterium tuberculosis"
xref
Reactome:REACT_115000 "UDP-galactose <=> UDP-glucose, Arabidopsis thaliana"
Reactome:REACT_115332 "UDP-galactose <=> UDP-glucose, Schizosaccharomyces pombe"
Reactome:REACT_115411 "UDP-galactose <=> UDP-glucose, Oryza sativa"
Reactome:REACT_94034 "UDP-galactose <=> UDP-glucose, Dictyostelium discoideum"
GO:0003979 : UDP-glucose 6-dehydrogenase activity
xref
Reactome:REACT_112524 "UDP-glucose is oxidised to UDP-glucuronate, Escherichia coli"
GO:0003985 : acetyl-CoA C-acetyltransferase activity
xref
Reactome:REACT_100461 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Danio rerio"
Reactome:REACT_102319 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Mycobacterium tuberculosis"
Reactome:REACT_102563 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Rattus norvegicus"
Reactome:REACT_103568 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Drosophila melanogaster"
Reactome:REACT_103940 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Canis familiaris"
Reactome:REACT_104958 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Mus musculus"
Reactome:REACT_105003 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Taeniopygia guttata"
Reactome:REACT_105426 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Bos taurus"
Reactome:REACT_105877 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Mycobacterium tuberculosis"
Reactome:REACT_106542 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Dictyostelium discoideum"
Reactome:REACT_109820 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Dictyostelium discoideum"
Reactome:REACT_109899 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Bos taurus"
Reactome:REACT_28462 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Plasmodium falciparum"
Reactome:REACT_28646 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Canis familiaris"
Reactome:REACT_31739 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Xenopus tropicalis"
Reactome:REACT_31976 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Xenopus tropicalis"
Reactome:REACT_32156 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Gallus gallus"
Reactome:REACT_47 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Homo sapiens"
Reactome:REACT_79103 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Schizosaccharomyces pombe"
Reactome:REACT_79150 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Rattus norvegicus"
Reactome:REACT_80937 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Saccharomyces cerevisiae"
Reactome:REACT_84180 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Gallus gallus"
Reactome:REACT_85056 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Danio rerio"
Reactome:REACT_85622 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Taeniopygia guttata"
Reactome:REACT_884 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Homo sapiens"
Reactome:REACT_92663 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Schizosaccharomyces pombe"
Reactome:REACT_92854 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Mus musculus"
Reactome:REACT_93946 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Drosophila melanogaster"
Reactome:REACT_96819 "2 acetyl-CoA <=> acetoacetyl-CoA+CoA, Plasmodium falciparum"
Reactome:REACT_97821 "acetoacetyl-CoA+CoA <=> 2 acetyl-CoA, Saccharomyces cerevisiae"
xref
Reactome:REACT_100461 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Danio rerio"
Reactome:REACT_102319 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Mycobacterium tuberculosis"
Reactome:REACT_102563 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Rattus norvegicus"
Reactome:REACT_103568 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Drosophila melanogaster"
Reactome:REACT_103940 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Canis familiaris"
Reactome:REACT_104958 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Mus musculus"
Reactome:REACT_105003 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Taeniopygia guttata"
Reactome:REACT_105426 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Bos taurus"
Reactome:REACT_105877 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Mycobacterium tuberculosis"
Reactome:REACT_106542 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Dictyostelium discoideum"
Reactome:REACT_109820 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Dictyostelium discoideum"
Reactome:REACT_109899 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Bos taurus"
Reactome:REACT_112932 "alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA, Caenorhabditis elegans"
Reactome:REACT_113533 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Caenorhabditis elegans"
Reactome:REACT_114812 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Caenorhabditis elegans"
Reactome:REACT_28462 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Plasmodium falciparum"
Reactome:REACT_28646 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Canis familiaris"
Reactome:REACT_31739 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Xenopus tropicalis"
Reactome:REACT_31976 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Xenopus tropicalis"
Reactome:REACT_32156 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Gallus gallus"
Reactome:REACT_47 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Homo sapiens"
Reactome:REACT_79103 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Schizosaccharomyces pombe"
Reactome:REACT_79150 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Rattus norvegicus"
Reactome:REACT_84180 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Gallus gallus"
Reactome:REACT_85056 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Danio rerio"
Reactome:REACT_85622 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Taeniopygia guttata"
Reactome:REACT_884 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Homo sapiens"
Reactome:REACT_92663 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Schizosaccharomyces pombe"
Reactome:REACT_92854 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Mus musculus"
Reactome:REACT_93946 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Drosophila melanogaster"
Reactome:REACT_96819 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Plasmodium falciparum"
Reactome:REACT_97416 "2 acetyl-CoA <=> acetoacetyl-CoA + CoA, Saccharomyces cerevisiae"
Reactome:REACT_97821 "acetoacetyl-CoA + CoA <=> 2 acetyl-CoA, Saccharomyces cerevisiae"
GO:0003986 : acetyl-CoA hydrolase activity
xref
Reactome:REACT_85181 "acetyl-CoA + H2O => acetate + CoASH, Sus scrofa"
xref
Reactome:REACT_89514 "acetyl-CoA + H2O => acetate + CoASH, Sus scrofa"
GO:0003987 : acetate-CoA ligase activity
xref
Reactome:REACT_93730 "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic], Sus scrofa"
xref
Reactome:REACT_112167 "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic], Escherichia coli"
Reactome:REACT_84415 "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic], Sus scrofa"
GO:0003989 : acetyl-CoA carboxylase activity
xref
Reactome:REACT_107532 "Formation of Malonyl-CoA from Acetyl-CoA (muscle), Bos taurus"
Reactome:REACT_28888 "Formation of Malonyl-CoA from Acetyl-CoA (muscle), Caenorhabditis elegans"
Reactome:REACT_77406 "acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate, Caenorhabditis elegans"
Reactome:REACT_78588 "acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate, Plasmodium falciparum"
Reactome:REACT_88371 "Formation of Malonyl-CoA from Acetyl-CoA (muscle), Plasmodium falciparum"
xref
Reactome:REACT_104374 "Formation of Malonyl-CoA from Acetyl-CoA (muscle), Bos taurus"
Reactome:REACT_114007 "Formation of Malonyl-CoA from Acetyl-CoA (muscle), Taeniopygia guttata"
GO:0003993 : acid phosphatase activity
xref
Reactome:REACT_91017 "FMN can be hydrolyzed back to riboflavin, Bos taurus"
xref
Reactome:REACT_82194 "FMN can be hydrolyzed back to riboflavin, Bos taurus"
GO:0003994 : aconitate hydratase activity
xref
Reactome:REACT_30425 "citrate <=> isocitrate, Escherichia coli"
GO:0003995 : acyl-CoA dehydrogenase activity
xref
Reactome:REACT_28144 "lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2, Sus scrofa"
Reactome:REACT_51199 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Bos taurus"
Reactome:REACT_77989 "Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2, Caenorhabditis elegans"
Reactome:REACT_82039 "dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA, Caenorhabditis elegans"
xref
Reactome:REACT_109051 "Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2, Caenorhabditis elegans"
Reactome:REACT_113088 "lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2, Staphylococcus aureus N315"
Reactome:REACT_113123 "myristoyl-CoA+FAD<=>trans-Tetradec-2-enoyl-CoA+FADH2, Staphylococcus aureus N315"
Reactome:REACT_114274 "palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2, Xenopus tropicalis"
Reactome:REACT_82463 "lauroyl-CoA+FAD<=>2-trans-Dodecenoyl-CoA+FADH2, Sus scrofa"
Reactome:REACT_99180 "dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA, Caenorhabditis elegans"
Reactome:REACT_99776 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Bos taurus"
GO:0003997 : acyl-CoA oxidase activity
xref
Reactome:REACT_109839 "25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA, Drosophila melanogaster"
Reactome:REACT_31895 "25(S) THCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA, Drosophila melanogaster"
Reactome:REACT_78265 "25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA, Dictyostelium discoideum"
Reactome:REACT_88619 "25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA, Caenorhabditis elegans"
Reactome:REACT_90244 "25(S) THCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA, Dictyostelium discoideum"
Reactome:REACT_99038 "hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2, Dictyostelium discoideum"
Reactome:REACT_99262 "25(S) THCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA, Caenorhabditis elegans"
xref
Reactome:REACT_114247 "hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2, Caenorhabditis elegans"
Reactome:REACT_115434 "hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2, Drosophila melanogaster"
GO:0003999 : adenine phosphoribosyltransferase activity
xref
Reactome:REACT_31898 "Adenine + PRPP => AMP + PPi, Saccharomyces cerevisiae"
Reactome:REACT_85316 "Adenine + PRPP => AMP + PPi, Arabidopsis thaliana"
Reactome:REACT_89305 "Adenine + PRPP => AMP + PPi, Oryza sativa"
xref
Reactome:REACT_84345 "Adenine + PRPP => AMP + PPi, Saccharomyces cerevisiae"
GO:0004000 : adenosine deaminase activity
xref
Reactome:REACT_29811 "(2'-deoxy)adenosine + H2O => (2'-deoxy)inosine + NH3 [ADA], Taeniopygia guttata"
Reactome:REACT_96491 "(2'-deoxy)adenosine + H2O => (2'-deoxy)inosine + NH3 [ADA], Xenopus tropicalis"
xref
Reactome:REACT_113447 "(2'-deoxy)adenosine + H2O => (2'-deoxy)inosine + NH3 [ADA], Plasmodium falciparum"
Reactome:REACT_114346 "(2'-deoxy)adenosine + H2O => (2'-deoxy)inosine + NH3 [ADA], Mycobacterium tuberculosis"
GO:0004001 : adenosine kinase activity
xref
Reactome:REACT_103469 "(2'-deoxy)adenosine + ATP => (d)AMP + ADP [ADK], Saccharomyces cerevisiae"
Reactome:REACT_107521 "(2'-deoxy)adenosine + ATP => (d)AMP + ADP [ADK], Drosophila melanogaster"
Reactome:REACT_28994 "(2'-deoxy)adenosine + ATP => (d)AMP + ADP [ADK], Sus scrofa"
xref
Reactome:REACT_112074 "(2'-deoxy)adenosine + ATP => (d)AMP + ADP [ADK], Oryza sativa"
Reactome:REACT_114269 "(2'-deoxy)adenosine + ATP => (d)AMP + ADP [ADK], Arabidopsis thaliana"
Reactome:REACT_32035 "(2'-deoxy)adenosine + ATP => (d)AMP + ADP [ADK], Saccharomyces cerevisiae"
Reactome:REACT_78906 "(2'-deoxy)adenosine + ATP => (d)AMP + ADP [ADK], Sus scrofa"
GO:0004008 : copper-exporting ATPase activity
synonym
"cu2+-exporting ATPase activity" EXACT [EC:3.6.3.4]
GO:0004013 : adenosylhomocysteinase activity
xref
Reactome:REACT_104928 "S-adenoylhomocysteine is hydrolyzed, Saccharomyces cerevisiae"
Reactome:REACT_78422 "S-adenoylhomocysteine is hydrolyzed, Plasmodium falciparum"
xref
Reactome:REACT_77951 "S-adenoylhomocysteine is hydrolyzed, Saccharomyces cerevisiae"
GO:0004016 : adenylate cyclase activity
xref
Reactome:REACT_108309 "Adenylate cyclase converts ATP into cyclic AMP, Dictyostelium discoideum"
Reactome:REACT_77141 "Production of Cyclic AMP by Activated Adenylyl Cyclase, Bos taurus"
Reactome:REACT_80895 "Activated Adenylate cyclase catalyses cAMP synthesis, Dictyostelium discoideum"
Reactome:REACT_88926 "Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate, Dictyostelium discoideum"
Reactome:REACT_92888 "Production of Cyclic AMP by Activated Adenylyl Cyclase, Dictyostelium discoideum"
xref
Reactome:REACT_110132 "Production of Cyclic AMP by Activated Adenylyl Cyclase, Bos taurus"
Reactome:REACT_114273 "Production of Cyclic AMP by Activated Adenylyl Cyclase, Xenopus tropicalis"
Reactome:REACT_114694 "Production of Cyclic AMP by Activated Adenylyl Cyclase, Drosophila melanogaster"
GO:0004017 : adenylate kinase activity
xref
Reactome:REACT_106045 "ADP + ADP <=> AMP + ATP [AK2], Saccharomyces cerevisiae"
Reactome:REACT_80241 "AMP + ATP <=> ADP + ADP [AK2], Saccharomyces cerevisiae"
Reactome:REACT_82179 "AMP + ATP <=> ADP + ADP [AK2], Mycobacterium tuberculosis"
Reactome:REACT_84293 "AMP + ATP <=> ADP + ADP [AK2], Staphylococcus aureus N315"
Reactome:REACT_91941 "ADP + ADP <=> AMP + ATP [AK2], Staphylococcus aureus N315"
Reactome:REACT_98422 "ADP + ADP <=> AMP + ATP [AK2], Mycobacterium tuberculosis"
xref
Reactome:REACT_106139 "ADP + ADP <=> AMP + ATP [AK2], Saccharomyces cerevisiae"
Reactome:REACT_114340 "(d)AMP + ATP <=> (d)ADP + ADP [AK1], Escherichia coli"
Reactome:REACT_114949 "(d)ADP + ADP <=> (d)AMP + ATP [AK1], Escherichia coli"
Reactome:REACT_80849 "AMP + ATP <=> ADP + ADP [AK2], Saccharomyces cerevisiae"
GO:0004018 : N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity
xref
Reactome:REACT_92629 "SAICAR => AICAR + Fumarate, Saccharomyces cerevisiae"
xref
Reactome:REACT_99135 "SAICAR => AICAR + Fumarate, Saccharomyces cerevisiae"
GO:0004019 : adenylosuccinate synthase activity
xref
Reactome:REACT_93022 "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS], Saccharomyces cerevisiae"
xref
Reactome:REACT_80422 "IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS], Saccharomyces cerevisiae"
GO:0004020 : adenylylsulfate kinase activity
xref
Reactome:REACT_77274 "adenylyl sulfate (APS) + ATP => PAPS + ADP, Saccharomyces cerevisiae"
Reactome:REACT_89526 "adenylyl sulfate (APS) + ATP => PAPS + ADP, Schizosaccharomyces pombe"
xref
Reactome:REACT_112719 "adenylyl sulfate (APS) + ATP => PAPS + ADP, Escherichia coli"
GO:0004024 : alcohol dehydrogenase activity, zinc-dependent
xref
Reactome:REACT_104324 "ethanol + NAD+ => acetaldehyde + NADH + H+, Caenorhabditis elegans"
Reactome:REACT_87603 "ethanol + NAD+ => acetaldehyde + NADH + H+, Drosophila melanogaster"
GO:0004027 : alcohol sulfotransferase activity
xref
Reactome:REACT_109667 "cholesterol + PAPS => cholesterol sulfate + PAP, Danio rerio"
Reactome:REACT_111003 "27-hydroxycholesterol + PAPS => 27-hydroxycholesterol 3-sulfate + PAP, Danio rerio"
GO:0004028 : 3-chloroallyl aldehyde dehydrogenase activity
xref
Reactome:REACT_92965 "gamma-butyrobetaine semialdehyde + NAD+ => gamma-butyrobetaine + NADH + H+, Schizosaccharomyces pombe"
GO:0004029 : aldehyde dehydrogenase (NAD) activity
xref
Reactome:REACT_103073 "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid, Schizosaccharomyces pombe"
Reactome:REACT_109613 "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial], Saccharomyces cerevisiae"
Reactome:REACT_54956 "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial], Schizosaccharomyces pombe"
Reactome:REACT_57539 "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic], Schizosaccharomyces pombe"
Reactome:REACT_86640 "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial], Sus scrofa"
Reactome:REACT_91697 "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid, Saccharomyces cerevisiae"
Reactome:REACT_99490 "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic], Saccharomyces cerevisiae"
xref
Reactome:REACT_112729 "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial], Dictyostelium discoideum"
Reactome:REACT_112808 "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic], Escherichia coli"
Reactome:REACT_113173 "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic], Rattus norvegicus"
Reactome:REACT_113214 "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid, Dictyostelium discoideum"
Reactome:REACT_113740 "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic], Mycobacterium tuberculosis"
Reactome:REACT_114032 "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid, Escherichia coli"
Reactome:REACT_114609 "5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid, Mycobacterium tuberculosis"
Reactome:REACT_115403 "acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic], Dictyostelium discoideum"
Reactome:REACT_86116 "acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial], Sus scrofa"
GO:0004032 : alditol:NADP+ 1-oxidoreductase activity
xref
Reactome:REACT_32685 "Reduction of isocaproaldehyde to 4-methylpentan-1-ol, Escherichia coli"
Reactome:REACT_93254 "Reduction of isocaproaldehyde to 4-methylpentan-1-ol, Schizosaccharomyces pombe"
xref
Reactome:REACT_112305 "Reduction of isocaproaldehyde to 4-methylpentan-1-ol, Arabidopsis thaliana"
Reactome:REACT_112358 "Reduction of isocaproaldehyde to 4-methylpentan-1-ol, Dictyostelium discoideum"
Reactome:REACT_114284 "Reduction of isocaproaldehyde to 4-methylpentan-1-ol, Oryza sativa"
GO:0004033 : aldo-keto reductase (NADP) activity
xref
Reactome:REACT_100788 "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol, Bos taurus"
Reactome:REACT_101445 "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol, Bos taurus"
Reactome:REACT_102302 "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol, Schizosaccharomyces pombe"
Reactome:REACT_103049 "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol, Rattus norvegicus"
Reactome:REACT_103289 "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol, Schizosaccharomyces pombe"
Reactome:REACT_103314 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Escherichia coli"
Reactome:REACT_105012 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol, Bos taurus"
Reactome:REACT_105354 "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one, Saccharomyces cerevisiae"
Reactome:REACT_105504 "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one, Sus scrofa"
Reactome:REACT_105832 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Schizosaccharomyces pombe"
Reactome:REACT_106044 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one, Schizosaccharomyces pombe"
Reactome:REACT_107571 "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one, Sus scrofa"
Reactome:REACT_108256 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Schizosaccharomyces pombe"
Reactome:REACT_109253 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol, Escherichia coli"
Reactome:REACT_31489 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Sus scrofa"
Reactome:REACT_32461 "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one, Schizosaccharomyces pombe"
Reactome:REACT_32624 "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol, Sus scrofa"
Reactome:REACT_33558 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one, Saccharomyces cerevisiae"
Reactome:REACT_33883 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol, Schizosaccharomyces pombe"
Reactome:REACT_33921 "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one, Schizosaccharomyces pombe"
Reactome:REACT_34226 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Bos taurus"
Reactome:REACT_50447 "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one, Schizosaccharomyces pombe"
Reactome:REACT_78223 "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one, Sus scrofa"
Reactome:REACT_78706 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Escherichia coli"
Reactome:REACT_78718 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol, Sus scrofa"
Reactome:REACT_80222 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Rattus norvegicus"
Reactome:REACT_80277 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol, Rattus norvegicus"
Reactome:REACT_81295 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Sus scrofa"
Reactome:REACT_81743 "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one, Sus scrofa"
Reactome:REACT_82019 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one, Escherichia coli"
Reactome:REACT_82969 "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol, Sus scrofa"
Reactome:REACT_84122 "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol, Rattus norvegicus"
Reactome:REACT_86091 "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol, Sus scrofa"
Reactome:REACT_86813 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one, Sus scrofa"
Reactome:REACT_87218 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Rattus norvegicus"
Reactome:REACT_87709 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Saccharomyces cerevisiae"
Reactome:REACT_89542 "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol, Rattus norvegicus"
Reactome:REACT_89861 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Bos taurus"
Reactome:REACT_90965 "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol, Schizosaccharomyces pombe"
Reactome:REACT_91607 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Saccharomyces cerevisiae"
Reactome:REACT_92432 "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one, Schizosaccharomyces pombe"
Reactome:REACT_94732 "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one, Schizosaccharomyces pombe"
Reactome:REACT_96023 "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one, Escherichia coli"
Reactome:REACT_97873 "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol, Bos taurus"
Reactome:REACT_98297 "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one, Escherichia coli"
Reactome:REACT_99652 "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one, Sus scrofa"
xref
Reactome:REACT_111993 "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one, Dictyostelium discoideum"
Reactome:REACT_112004 "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one, Dictyostelium discoideum"
Reactome:REACT_112078 "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol, Drosophila melanogaster"
Reactome:REACT_112094 "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one, Dictyostelium discoideum"
Reactome:REACT_112136 "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one, Drosophila melanogaster"
Reactome:REACT_112164 "Reduction of semidehydroascorbate to ascorbate, Dictyostelium discoideum"
Reactome:REACT_112352 "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol, Dictyostelium discoideum"
Reactome:REACT_112380 "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one, Oryza sativa"
Reactome:REACT_112446 "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol, Arabidopsis thaliana"
Reactome:REACT_112477 "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol, Drosophila melanogaster"
Reactome:REACT_112538 "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one, Oryza sativa"
Reactome:REACT_112546 "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol, Arabidopsis thaliana"
Reactome:REACT_112547 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol, Arabidopsis thaliana"
Reactome:REACT_112635 "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol, Dictyostelium discoideum"
Reactome:REACT_112765 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Oryza sativa"
Reactome:REACT_112786 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Drosophila melanogaster"
Reactome:REACT_112971 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Drosophila melanogaster"
Reactome:REACT_113067 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Dictyostelium discoideum"
Reactome:REACT_113108 "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one, Dictyostelium discoideum"
Reactome:REACT_113453 "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one, Oryza sativa"
Reactome:REACT_113482 "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one, Drosophila melanogaster"
Reactome:REACT_113545 "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one, Drosophila melanogaster"
Reactome:REACT_113590 "4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one, Arabidopsis thaliana"
Reactome:REACT_113657 "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol, Arabidopsis thaliana"
Reactome:REACT_113694 "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one, Drosophila melanogaster"
Reactome:REACT_113742 "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol, Dictyostelium discoideum"
Reactome:REACT_113762 "5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol, Oryza sativa"
Reactome:REACT_113791 "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one, Arabidopsis thaliana"
Reactome:REACT_113879 "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one, Oryza sativa"
Reactome:REACT_113982 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Arabidopsis thaliana"
Reactome:REACT_114182 "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one, Drosophila melanogaster"
Reactome:REACT_114303 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Arabidopsis thaliana"
Reactome:REACT_114413 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Oryza sativa"
Reactome:REACT_114451 "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol, Oryza sativa"
Reactome:REACT_114529 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol, Drosophila melanogaster"
Reactome:REACT_114561 "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol, Oryza sativa"
Reactome:REACT_114574 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Dictyostelium discoideum"
Reactome:REACT_114601 "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one, Dictyostelium discoideum"
Reactome:REACT_114670 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one, Arabidopsis thaliana"
Reactome:REACT_114682 "4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one, Oryza sativa"
Reactome:REACT_114688 "5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol, Drosophila melanogaster"
Reactome:REACT_114788 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one, Oryza sativa"
Reactome:REACT_114934 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol, Oryza sativa"
Reactome:REACT_114943 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one, Dictyostelium discoideum"
Reactome:REACT_114951 "5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol, Dictyostelium discoideum"
Reactome:REACT_115178 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one, Drosophila melanogaster"
Reactome:REACT_115352 "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one, Arabidopsis thaliana"
Reactome:REACT_115369 "4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one, Arabidopsis thaliana"
Reactome:REACT_115407 "4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one, Arabidopsis thaliana"
Reactome:REACT_79323 "4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one, Saccharomyces cerevisiae"
Reactome:REACT_83433 "4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one, Saccharomyces cerevisiae"
Reactome:REACT_85587 "5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol, Saccharomyces cerevisiae"
Reactome:REACT_95886 "5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol, Saccharomyces cerevisiae"
GO:0004051 : arachidonate 5-lipoxygenase activity
xref
Reactome:REACT_113814 "Dehydration of 5-HpETE to leukotriene A4, Dictyostelium discoideum"
Reactome:REACT_115370 "Oxidation of arachidonic acid to 5-HpETE, Dictyostelium discoideum"
GO:0004053 : arginase activity
xref
Reactome:REACT_89208 "arginine + H2O => ornithine + urea [ARG1], Bos taurus"
xref
Reactome:REACT_112789 "arginine + H2O => ornithine + urea [ARG1], Caenorhabditis elegans"
Reactome:REACT_99000 "arginine + H2O => ornithine + urea [ARG1], Bos taurus"
GO:0004055 : argininosuccinate synthase activity
xref
Reactome:REACT_113640 "ATP + aspartate + citrulline <=> argininosuccinate + AMP + pyrophosphate, Gallus gallus"
GO:0004056 : argininosuccinate lyase activity
xref
Reactome:REACT_113182 "argininosuccinate <=> fumarate + arginine, Staphylococcus aureus N315"
Reactome:REACT_114192 "argininosuccinate <=> fumarate + arginine, Arabidopsis thaliana"
Reactome:REACT_114884 "argininosuccinate <=> fumarate + arginine, Escherichia coli"
Reactome:REACT_115252 "argininosuccinate <=> fumarate + arginine, Oryza sativa"
GO:0004060 : arylamine N-acetyltransferase activity
xref
Reactome:REACT_113266 "NAT1 acetylation, Staphylococcus aureus N315"
Reactome:REACT_115264 "NAT2 acetylation, Staphylococcus aureus N315"
GO:0004062 : aryl sulfotransferase activity
xref
Reactome:REACT_105993 "N-hydroxy-4-aminobiphenyl can form a sulfate conjugate, Gallus gallus"
Reactome:REACT_77257 "Dopamine can form an O-sulfate conjugate, Gallus gallus"
Reactome:REACT_88015 "Phenol can form a sulfate conjugate, Gallus gallus"
Reactome:REACT_99781 "Acetaminophen can form an O- sulfate conjugate, Gallus gallus"
Reactome:REACT_99792 "p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP, Bos taurus"
xref
Reactome:REACT_104618 "p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP, Bos taurus"
Reactome:REACT_112861 "p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP, Rattus norvegicus"
Reactome:REACT_113420 "Dopamine can form an O-sulfate conjugate, Danio rerio"
Reactome:REACT_113755 "Acetaminophen can form an O- sulfate conjugate, Rattus norvegicus"
Reactome:REACT_113826 "Acetaminophen can form an O- sulfate conjugate, Danio rerio"
Reactome:REACT_114350 "Phenol can form a sulfate conjugate, Rattus norvegicus"
Reactome:REACT_114511 "Phenol can form a sulfate conjugate, Danio rerio"
Reactome:REACT_114894 "N-hydroxy-4-aminobiphenyl can form a sulfate conjugate, Danio rerio"
Reactome:REACT_115246 "N-hydroxy-4-aminobiphenyl can form a sulfate conjugate, Rattus norvegicus"
Reactome:REACT_115272 "Dopamine can form an O-sulfate conjugate, Rattus norvegicus"
GO:0004066 : asparagine synthase (glutamine-hydrolyzing) activity
xref
Reactome:REACT_29427 "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS], Dictyostelium discoideum"
xref
Reactome:REACT_112740 "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS], Oryza sativa"
Reactome:REACT_113607 "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS], Arabidopsis thaliana"
Reactome:REACT_114769 "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS], Saccharomyces cerevisiae"
Reactome:REACT_81036 "aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS], Dictyostelium discoideum"
GO:0004069 : L-aspartate:2-oxoglutarate aminotransferase activity
xref
Reactome:REACT_104938 "aspartate + alpha-ketoglutarate <=> oxaloacetate + glutamate [GOT1], Bos taurus"
xref
Reactome:REACT_112410 "aspartate + alpha-ketoglutarate <=> oxaloacetate + glutamate [GOT1], Plasmodium falciparum"
Reactome:REACT_112542 "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2], Plasmodium falciparum"
Reactome:REACT_113079 "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1], Plasmodium falciparum"
Reactome:REACT_115016 "oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2], Rattus norvegicus"
Reactome:REACT_115018 "aspartate + alpha-ketoglutarate <=> oxaloacetate + glutamate [GOT2], Rattus norvegicus"
Reactome:REACT_115062 "aspartate + alpha-ketoglutarate <=> oxaloacetate + glutamate [GOT2], Plasmodium falciparum"
Reactome:REACT_84706 "aspartate + alpha-ketoglutarate <=> oxaloacetate + glutamate [GOT1], Bos taurus"
GO:0004070 : aspartate carbamoyltransferase activity
xref
Reactome:REACT_33708 "carbamoyl phosphate + L-aspartate <=> N-carbamoyl L-aspartate + orthophosphate, Gallus gallus"
Reactome:REACT_88613 "carbamoyl phosphate + L-aspartate <=> N-carbamoyl L-aspartate + orthophosphate, Xenopus tropicalis"
GO:0004084 : branched-chain-amino-acid transaminase activity
xref
Reactome:REACT_81908 "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2], Danio rerio"
xref
Reactome:REACT_112447 "leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1], Xenopus tropicalis"
GO:0004087 : carbamoyl-phosphate synthase (ammonia) activity
xref
Reactome:REACT_112052 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial], Plasmodium falciparum"
Reactome:REACT_112191 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial], Saccharomyces cerevisiae"
Reactome:REACT_112781 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial], Schizosaccharomyces pombe"
GO:0004088 : carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
xref
Reactome:REACT_89022 "L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate, Gallus gallus"
Reactome:REACT_95136 "L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate, Xenopus tropicalis"
GO:0004092 : carnitine O-acetyltransferase activity
xref
Reactome:REACT_108990 "propionyl-CoA + carnitine => propionylcarnitine + CoASH, Caenorhabditis elegans"
Reactome:REACT_81182 "propionyl-CoA + carnitine => propionylcarnitine + CoASH, Drosophila melanogaster"
Reactome:REACT_89111 "acetyl-CoA + carnitine => acetylcarnitine + CoASH, Drosophila melanogaster"
Reactome:REACT_90477 "acetyl-CoA + carnitine => acetylcarnitine + CoASH, Caenorhabditis elegans"
GO:0004096 : catalase activity
xref
Reactome:REACT_89257 "2 H2O2 => O2 + 2 H2O, Sus scrofa"
Reactome:REACT_97652 "2 H2O2 => O2 + 2 H2O, Schizosaccharomyces pombe"
xref
Reactome:REACT_112160 "2 H2O2 => O2 + 2 H2O, Caenorhabditis elegans"
Reactome:REACT_79757 "2 H2O2 => O2 + 2 H2O, Schizosaccharomyces pombe"
Reactome:REACT_89864 "2 H2O2 => O2 + 2 H2O, Sus scrofa"
GO:0004100 : chitin synthase activity
def
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n) = UDP + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n+1).
def
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n) = UDP + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n+1).
GO:0004104 : cholinesterase activity
xref
Reactome:REACT_33172 "Acetylcholine clearance from synaptic cleft, Drosophila melanogaster"
Reactome:REACT_88765 "Acetylcholine clearance from synaptic cleft, Caenorhabditis elegans"
GO:0004108 : citrate (Si)-synthase activity
xref
Reactome:REACT_102926 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Saccharomyces cerevisiae"
Reactome:REACT_30454 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Sus scrofa"
xref
Reactome:REACT_96879 "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA, Sus scrofa"
GO:0004111 : creatine kinase activity
xref
Reactome:REACT_102773 "creatine + ATP => phosphocreatine + ADP [CK octamer], Sus scrofa"
xref
Reactome:REACT_111938 "creatine + ATP => phosphocreatine + ADP [CKB,CKM], Staphylococcus aureus N315"
Reactome:REACT_112531 "creatine + ATP => phosphocreatine + ADP [CK octamer], Staphylococcus aureus N315"
Reactome:REACT_113875 "creatine + ATP => phosphocreatine + ADP [CK octamer], Rattus norvegicus"
Reactome:REACT_34284 "creatine + ATP => phosphocreatine + ADP [CK octamer], Sus scrofa"
GO:0004114 : 3',5'-cyclic-nucleotide phosphodiesterase activity
xref
Reactome:REACT_93497 "Hydrolysis of cAMP to 5' AMP by Phosphorylated PDE3B, Sus scrofa"
xref
Reactome:REACT_114232 "Hydrolysis of cAMP to 5' AMP by Phosphorylated PDE3B, Plasmodium falciparum"
Reactome:REACT_82008 "Hydrolysis of cAMP to 5' AMP by Phosphorylated PDE3B, Sus scrofa"
GO:0004115 : 3',5'-cyclic-AMP phosphodiesterase activity
xref
Reactome:REACT_51952 "cAMP degradation by Phosphodiesterases, Plasmodium falciparum"
xref
Reactome:REACT_112238 "cAMP hydrolysis by PDE 4, Dictyostelium discoideum"
Reactome:REACT_115186 "cAMP hydrolysis by PDE 4, Plasmodium falciparum"
Reactome:REACT_77308 "cAMP degradation by Phosphodiesterases, Plasmodium falciparum"
GO:0004117 : calmodulin-dependent cyclic-nucleotide phosphodiesterase activity
xref
Reactome:REACT_114149 "cAMP hydrolysis by Cam-PDE 1, Dictyostelium discoideum"
Reactome:REACT_114485 "cAMP hydrolysis by Cam-PDE 1, Plasmodium falciparum"
GO:0004128 : cytochrome-b5 reductase activity
xref
Reactome:REACT_91203 "Reduction of ferric cytochrome B5A to ferrous cytochrome B5A, Caenorhabditis elegans"
Reactome:REACT_95013 "Reduction of ferric cytochrome B5A to ferrous cytochrome B5A, Drosophila melanogaster"
GO:0004129 : cytochrome-c oxidase activity
xref
Reactome:REACT_113276 "Electron transfer from reduced cytochrome c to molecular oxygen, Bos taurus"
Reactome:REACT_113311 "Electron transfer from reduced cytochrome c to molecular oxygen, Sus scrofa"
Reactome:REACT_113736 "Electron transfer from reduced cytochrome c to molecular oxygen, Canis familiaris"
Reactome:REACT_115027 "Electron transfer from reduced cytochrome c to molecular oxygen, Rattus norvegicus"
GO:0004134 : 4-alpha-glucanotransferase activity
def
Catalysis of the transfer of a segment of a (1,4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1,4)-alpha-D-glucan.
def
Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1->4)-alpha-D-glucan.
GO:0004135 : amylo-alpha-1,6-glucosidase activity
def
Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the 1,6 glycosidic linkages present.
def
Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the (1->6) glycosidic linkages present.
GO:0004140 : dephospho-CoA kinase activity
xref
Reactome:REACT_80050 "Phosphorylation of dephospho-CoA to produce CoA, Mycobacterium tuberculosis"
xref
Reactome:REACT_112662 "Phosphorylation of dephospho-CoA to produce CoA, Plasmodium falciparum"
GO:0004143 : diacylglycerol kinase activity
xref
Reactome:REACT_100005 "DAG kinase produces phosphatidic acid from DAG, Sus scrofa"
Reactome:REACT_31006 "DAG kinase produces phosphatidic acid from DAG, Dictyostelium discoideum"
xref
Reactome:REACT_100005 "DAG kinase produces phosphatidic acid from DAG, Sus scrofa > GO:"
GO:0004144 : diacylglycerol O-acyltransferase activity
xref
Reactome:REACT_103954 "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2], Drosophila melanogaster"
Reactome:REACT_31508 "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2], Sus scrofa"
Reactome:REACT_94299 "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2], Caenorhabditis elegans"
xref
Reactome:REACT_112540 "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2], Arabidopsis thaliana"
Reactome:REACT_112715 "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2], Schizosaccharomyces pombe"
Reactome:REACT_114635 "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2], Oryza sativa"
Reactome:REACT_28392 "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2], Sus scrofa"
GO:0004145 : diamine N-acetyltransferase activity
xref
Reactome:REACT_87724 "Spermine => N-acetylated spermine, Caenorhabditis elegans"
xref
Reactome:REACT_86359 "Spermine => N-acetylated spermine, Caenorhabditis elegans"
GO:0004146 : dihydrofolate reductase activity
xref
Reactome:REACT_111041 "Salvage - BH2 is reduced to BH4 by DHFR, Homo sapiens"
GO:0004151 : dihydroorotase activity
xref
Reactome:REACT_110467 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Gallus gallus"
Reactome:REACT_77509 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Caenorhabditis elegans"
Reactome:REACT_87197 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Xenopus tropicalis"
xref
Reactome:REACT_33026 "N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O, Caenorhabditis elegans"
GO:0004157 : dihydropyrimidinase activity
xref
Reactome:REACT_82913 "5,6-dihydrothymine + H2O => beta-ureidoisobutyrate, Caenorhabditis elegans"
Reactome:REACT_94118 "5,6-dihydrouracil + H2O => beta-ureidopropionate, Caenorhabditis elegans"
xref
Reactome:REACT_113000 "5,6-dihydrothymine + H2O => beta-ureidoisobutyrate, Drosophila melanogaster"
Reactome:REACT_113669 "5,6-dihydrouracil + H2O => beta-ureidopropionate, Drosophila melanogaster"
GO:0004163 : diphosphomevalonate decarboxylase activity
xref
Reactome:REACT_79689 "Mevalonate-5-pyrophosphate is decarboxylated, Schizosaccharomyces pombe"
xref
Reactome:REACT_33654 "Mevalonate-5-pyrophosphate is decarboxylated, Schizosaccharomyces pombe"
GO:0004174 : electron-transferring-flavoprotein dehydrogenase activity
xref
Reactome:REACT_108818 "Transfer of electrons from ETF to ubiquinone by ETF-QO, Saccharomyces cerevisiae"
Reactome:REACT_94188 "Transfer of electrons from ETF to ubiquinone by ETF-QO, Sus scrofa"
xref
Reactome:REACT_32665 "Transfer of electrons from ETF to ubiquinone by ETF-QO, Saccharomyces cerevisiae"
Reactome:REACT_34198 "Transfer of electrons from ETF to ubiquinone by ETF-QO, Sus scrofa"
GO:0004175 : endopeptidase activity
xref
Reactome:REACT_100671 "Ubiquitinated Cdc6 is degraded by the proteasome, Taeniopygia guttata"
Reactome:REACT_101545 "Degradation of ubiquitinated -beta catenin by the proteasome, Taeniopygia guttata"
Reactome:REACT_102304 "Proteasome mediated degradation of COP1, Arabidopsis thaliana"
Reactome:REACT_102595 "Proteasome mediated degradation of PAK-2p34, Taeniopygia guttata"
Reactome:REACT_102836 "Degradation of multiubiquitinated Cdh1, Arabidopsis thaliana"
Reactome:REACT_104263 "Proteasome mediated degradation of COP1, Taeniopygia guttata"
Reactome:REACT_104484 "Degradation of multiubiquitinated Cdh1, Taeniopygia guttata"
Reactome:REACT_105110 "Ubiquitinated geminin is degraded by the proteasome, Taeniopygia guttata"
Reactome:REACT_106215 "Ubiquitinated Orc1 is degraded by the proteasome, Taeniopygia guttata"
Reactome:REACT_109046 "SCF-mediated degradation of Emi1, Bos taurus"
Reactome:REACT_110179 "Proteolytic degradation of ubiquitinated-Cdc25A, Dictyostelium discoideum"
Reactome:REACT_110886 "SCF-mediated degradation of Emi1, Taeniopygia guttata"
Reactome:REACT_28162 "Ubiquitinated Cdc6 is degraded by the proteasome, Saccharomyces cerevisiae"
Reactome:REACT_28760 "Ubiquitinated Cdc6 is degraded by the proteasome, Schizosaccharomyces pombe"
Reactome:REACT_32577 "Degradation multiubiquitinated Cyclin A, Taeniopygia guttata"
Reactome:REACT_33799 "Proteasome mediated degradation of Cyclin D1, Taeniopygia guttata"
Reactome:REACT_38654 "Ubiquitinated Cdc6 is degraded by the proteasome, Caenorhabditis elegans"
Reactome:REACT_77036 "Degradation of multiubiquitinated Securin, Taeniopygia guttata"
Reactome:REACT_78474 "Degradation of multiubiquitinated cell cycle proteins, Taeniopygia guttata"
Reactome:REACT_81430 "APC/C:Cdh1-mediated degradation of Skp2, Arabidopsis thaliana"
Reactome:REACT_85553 "Ubiquitinated Cdc6 is degraded by the proteasome, Arabidopsis thaliana"
Reactome:REACT_87600 "Proteasome mediated degradation of PAK-2p34, Caenorhabditis elegans"
Reactome:REACT_88805 "Ubiquitinated Orc1 is degraded by the proteasome, Saccharomyces cerevisiae"
Reactome:REACT_89575 "Degradation of multiubiquitinated Securin, Arabidopsis thaliana"
Reactome:REACT_90352 "Proteasome mediated degradation of PAK-2p34, Schizosaccharomyces pombe"
Reactome:REACT_91168 "26S proteosome degrades ODC holoenzyme complex, Taeniopygia guttata"
Reactome:REACT_91983 "Ubiquitinated Orc1 is degraded by the proteasome, Arabidopsis thaliana"
Reactome:REACT_92274 "Proteasome mediated degradation of PAK-2p34, Saccharomyces cerevisiae"
Reactome:REACT_94246 "APC/C:Cdh1-mediated degradation of Skp2, Taeniopygia guttata"
Reactome:REACT_94571 "Ubiquitinated Orc1 is degraded by the proteasome, Schizosaccharomyces pombe"
Reactome:REACT_95228 "Proteolytic degradation of ubiquitinated-Cdc25A, Taeniopygia guttata"
Reactome:REACT_95706 "SCF-mediated degradation of Emi1, Caenorhabditis elegans"
Reactome:REACT_96564 "Proteasome mediated degradation of PAK-2p34, Dictyostelium discoideum"
Reactome:REACT_97537 "SCF-mediated degradation of Emi1, Schizosaccharomyces pombe"
Reactome:REACT_97698 "Degradation of multiubiquitinated cell cycle proteins, Arabidopsis thaliana"
xref
Reactome:REACT_106687 "SCF-mediated degradation of Emi1, Bos taurus"
Reactome:REACT_111098 "Processing of SCF isoform 1, Homo sapiens"
Reactome:REACT_111104 "Proteasomal cleavage of substrate, Homo sapiens"
Reactome:REACT_111172 "Proteasomal clevage of exogenous antigen, Homo sapiens"
Reactome:REACT_112076 "Ubiquitinated Cdc6 is degraded by the proteasome, Sus scrofa"
Reactome:REACT_113623 "Ubiquitinated geminin is degraded by the proteasome, Sus scrofa"
Reactome:REACT_113749 "Ubiquitinated Orc1 is degraded by the proteasome, Sus scrofa"
Reactome:REACT_114002 "Proteasome mediated degradation of PAK-2p34, Sus scrofa"
Reactome:REACT_114449 "Proteasome mediated degradation of Cyclin D1, Sus scrofa"
Reactome:REACT_114993 "Proteasome mediated degradation of COP1, Sus scrofa"
Reactome:REACT_115363 "Proteasome mediated degradation of Cyclin D1, Oryza sativa"
GO:0004177 : aminopeptidase activity
xref
Reactome:REACT_111222 "Trimming of peptides by IRAP in endocytic vesicles, Homo sapiens"
GO:0004190 : aspartic-type endopeptidase activity
xref
Reactome:REACT_100023 "NEXT2 is cleaved to produce NICD2, Taeniopygia guttata"
Reactome:REACT_105745 "NEXT4 is cleaved to produce NICD4, Sus scrofa"
Reactome:REACT_95986 "NEXT2 is cleaved to produce NICD2, Sus scrofa"
xref
Reactome:REACT_114839 "NEXT4 is cleaved to produce NICD4, Xenopus tropicalis"
Reactome:REACT_114927 "NEXT3 is cleaved to produce NICD3, Drosophila melanogaster"
Reactome:REACT_29012 "NEXT4 is cleaved to produce NICD4, Sus scrofa"
Reactome:REACT_93980 "NEXT2 is cleaved to produce NICD2, Sus scrofa"
GO:0004197 : cysteine-type endopeptidase activity
xref
Reactome:REACT_110981 "Caspase-mediated cleavage of claspin, Sus scrofa"
Reactome:REACT_33402 "Caspase-mediated cleavage of E-Cadherin, Xenopus tropicalis"
Reactome:REACT_78903 "Caspase-mediated cleavage of gelsolin, Taeniopygia guttata"
Reactome:REACT_79807 "Caspase-mediated cleavage of gelsolin, Xenopus tropicalis"
xref
Reactome:REACT_111140 "Antigen processing by cathepsin S in endosoytic vesicle, Homo sapiens"
Reactome:REACT_111954 "Cleavage of Procaspase-7 by the apoptosome, Rattus norvegicus"
Reactome:REACT_112287 "Activation of caspase-3, Xenopus tropicalis"
Reactome:REACT_112363 "Cleavage of Procaspase-9 to Caspase-9, Sus scrofa"
Reactome:REACT_112407 "Caspase mediated cleavage of vimentin at IDVD (259), Caenorhabditis elegans"
Reactome:REACT_112426 "Caspase-mediated cleavage of Desmoglein 1, Xenopus tropicalis"
Reactome:REACT_112597 "Caspase-mediated cleavage of Desmoglein 3, Xenopus tropicalis"
Reactome:REACT_112616 "Cleavage of Procaspase-7 by the apoptosome, Sus scrofa"
Reactome:REACT_112859 "Cleavage of Procaspase-7 by the apoptosome, Canis familiaris"
Reactome:REACT_113141 "Cleavage of Procaspase-9 to Caspase-9, Canis familiaris"
Reactome:REACT_113277 "Cleavage of Procaspase-3 by the apoptosome, Canis familiaris"
Reactome:REACT_113588 "Caspase-mediated cleavage of Desmoglein 2, Xenopus tropicalis"
Reactome:REACT_113941 "Cleavage of Procaspase-3 by the apoptosome, Sus scrofa"
Reactome:REACT_114270 "Caspase mediated cleavage of alpha-II-Fodrin, Xenopus tropicalis"
Reactome:REACT_114354 "Cleavage of Procaspase-3 by the apoptosome, Bos taurus"
Reactome:REACT_114571 "Cleavage of Procaspase-7 by the apoptosome, Bos taurus"
Reactome:REACT_114579 "Cleavage of Procaspase-9 to Caspase-9, Rattus norvegicus"
Reactome:REACT_114638 "Caspase-mediated cleavage of Acinus, Xenopus tropicalis"
Reactome:REACT_114872 "Caspase mediated cleavage of BAP31, Caenorhabditis elegans"
Reactome:REACT_115070 "Caspase-mediated cleavage of Rock-1, Canis familiaris"
Reactome:REACT_115257 "Cleavage of Procaspase-3 by the apoptosome, Rattus norvegicus"
Reactome:REACT_115318 "Caspase-mediated cleavage of plectin-1, Taeniopygia guttata"
Reactome:REACT_115379 "Cleavage of Procaspase-9 to Caspase-9, Bos taurus"
Reactome:REACT_91694 "Caspase-mediated cleavage of claspin, Sus scrofa"
GO:0004219 : pyroglutamyl-peptidase I activity
synonym
"pyrase activity" EXACT [EC:3.4.19.3]
GO:0004222 : metalloendopeptidase activity
xref
Reactome:REACT_110874 "Proteolysis of the IGF:IGFBP-4 Complex by PAPP-A, Bos taurus"
Reactome:REACT_86614 "Proteolysis of the IGF:IGFBP-3:ALS Complex by Matrix Metalloproteinase, Bos taurus"
Reactome:REACT_90189 "Proteolysis of the IGF:IGFBP-5:ALS Complex by PAPP-A2, Bos taurus"
xref
Reactome:REACT_102187 "Proteolysis of the IGF:IGFBP-4 Complex by PAPP-A, Bos taurus"
Reactome:REACT_111084 "ADAM17 cleavage of Ghr, Mus musculus"
Reactome:REACT_111197 "Metalloprotease cleavage of GHR, Homo sapiens"
Reactome:REACT_30876 "Proteolysis of the IGF:IGFBP-5:ALS Complex by PAPP-A2, Bos taurus"
Reactome:REACT_32065 "Proteolysis of the IGF:IGFBP-3:ALS Complex by Matrix Metalloproteinase, Bos taurus"
GO:0004252 : serine-type endopeptidase activity
xref
Reactome:REACT_101759 "plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [two-chain] catalyst), Sus scrofa"
Reactome:REACT_104427 "pro-factor X -> factor X + factor X propeptide, Sus scrofa"
Reactome:REACT_105217 "crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain), Sus scrofa"
Reactome:REACT_107130 "Activation of C1S, Danio rerio"
Reactome:REACT_108422 "Activation of C5, Xenopus tropicalis"
Reactome:REACT_29374 "Conversion of C4 into C4a and C4b, Danio rerio"
Reactome:REACT_31776 "Proteolysis of the IGF:IGFBP-3:ALS Complex by Thrombin, Bos taurus"
Reactome:REACT_32038 "crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin, Sus scrofa"
Reactome:REACT_33163 "Cleavage of C3 by C3 convertases, Xenopus tropicalis"
Reactome:REACT_33696 "Proteolysis of the IGF:IGFBP-3:ALS Complex by Cathepsin G, Bos taurus"
Reactome:REACT_34485 "Proteolysis of the IGF:IGFBP-3:ALS Complex by Plasmin, Bos taurus"
Reactome:REACT_78068 "protein C -> activated protein C + protein C heavy chain activation peptide, Danio rerio"
Reactome:REACT_78443 "Notch 2 precursor cleaved to form a heterodimer, Taeniopygia guttata"
Reactome:REACT_79717 "Processing of classical PDGFs, Drosophila melanogaster"
Reactome:REACT_82757 "crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin, Sus scrofa"
Reactome:REACT_83024 "Activation of C1S, Canis familiaris"
Reactome:REACT_83288 "urokinase plasminogen activator (one-chain):uPAR -> urokinase plasminogen activator (two-chain):uPAR, Sus scrofa"
Reactome:REACT_83945 "Processing of classical PDGFs, Caenorhabditis elegans"
Reactome:REACT_84855 "Activation of C1S, Gallus gallus"
Reactome:REACT_84935 "Conversion of C2 into C2a and C2b, Xenopus tropicalis"
Reactome:REACT_90529 "pro-protein S -> protein S + protein S propeptide, Sus scrofa"
Reactome:REACT_91922 "Conversion of C2 into C2a and C2b, Danio rerio"
Reactome:REACT_92283 "Activation of C1S, Taeniopygia guttata"
Reactome:REACT_93023 "Activation of C1R, Canis familiaris"
Reactome:REACT_93607 "Activation of C1R, Gallus gallus"
Reactome:REACT_93727 "pro-factor IX -> factor IX + factor IX propeptide, Sus scrofa"
Reactome:REACT_96691 "Activation of C1R, Taeniopygia guttata"
Reactome:REACT_97222 "pro-prothrombin -> prothrombin + prothrombin propeptide, Sus scrofa"
Reactome:REACT_98087 "plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [one-chain] catalyst), Sus scrofa"
Reactome:REACT_98547 "Activation of C1R, Danio rerio"
xref
Reactome:REACT_102247 "urokinase plasminogen activator (one-chain):uPAR -> urokinase plasminogen activator (two-chain):uPAR, Sus scrofa"
Reactome:REACT_104930 "pro-factor IX -> factor IX + factor IX propeptide, Sus scrofa"
Reactome:REACT_107456 "plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [two-chain] catalyst), Sus scrofa"
Reactome:REACT_107946 "pro-protein S -> protein S + protein S propeptide, Sus scrofa"
Reactome:REACT_111180 "Cleavage of Nodal Proprotein, Mus musculus"
Reactome:REACT_111228 "Cleavage of NODAL Proprotein, Homo sapiens"
Reactome:REACT_112053 "factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst), Canis familiaris"
Reactome:REACT_112058 "factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst), Xenopus tropicalis"
Reactome:REACT_112131 "factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst), Gallus gallus"
Reactome:REACT_112143 "factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst), Bos taurus"
Reactome:REACT_112184 "crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin, Xenopus tropicalis"
Reactome:REACT_112194 "factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst), Danio rerio"
Reactome:REACT_112204 "factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer, Sus scrofa"
Reactome:REACT_112253 "factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides, Danio rerio"
Reactome:REACT_112277 "Granzyme-B activates BID by cleavage, Xenopus tropicalis"
Reactome:REACT_112440 "factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst), Xenopus tropicalis"
Reactome:REACT_112453 "Notch 3 precursor cleaved to form a heterodimer, Drosophila melanogaster"
Reactome:REACT_112489 "factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer, Bos taurus"
Reactome:REACT_112510 "factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer, Rattus norvegicus"
Reactome:REACT_112572 "Cleavage of the Signal Peptide of Preproinsulin, Gallus gallus"
Reactome:REACT_112675 "factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer, Xenopus tropicalis"
Reactome:REACT_112763 "Notch 4 precursor cleaved to form a heterodimer, Xenopus tropicalis"
Reactome:REACT_112800 "Latent TGF-beta1 is cleaved by furin, Caenorhabditis elegans"
Reactome:REACT_112843 "factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst), Xenopus tropicalis"
Reactome:REACT_113002 "factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst), Rattus norvegicus"
Reactome:REACT_113239 "factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer, Gallus gallus"
Reactome:REACT_113539 "factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst), Taeniopygia guttata"
Reactome:REACT_113596 "factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst), Xenopus tropicalis"
Reactome:REACT_113760 "factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst), Sus scrofa"
Reactome:REACT_113831 "crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain), Xenopus tropicalis"
Reactome:REACT_114057 "fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B, Sus scrofa"
Reactome:REACT_114147 "factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer, Mus musculus"
Reactome:REACT_114209 "factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer, Canis familiaris"
Reactome:REACT_114347 "factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides, Xenopus tropicalis"
Reactome:REACT_114464 "crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin, Xenopus tropicalis"
Reactome:REACT_114654 "Cleavage of the Signal Peptide of Preproinsulin, Rattus norvegicus"
Reactome:REACT_115043 "Latent TGF-beta1 is cleaved by furin, Drosophila melanogaster"
Reactome:REACT_115078 "factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer, Danio rerio"
Reactome:REACT_115086 "factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer, Taeniopygia guttata"
Reactome:REACT_115256 "factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst), Mus musculus"
Reactome:REACT_115338 "protein C -> activated protein C + protein C heavy chain activation peptide, Xenopus tropicalis"
Reactome:REACT_28152 "pro-prothrombin -> prothrombin + prothrombin propeptide, Sus scrofa"
Reactome:REACT_78477 "crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain), Sus scrofa"
Reactome:REACT_79426 "crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin, Sus scrofa"
Reactome:REACT_83770 "Proteolysis of the IGF:IGFBP-3:ALS Complex by Cathepsin G, Bos taurus"
Reactome:REACT_84305 "pro-factor X -> factor X + factor X propeptide, Sus scrofa"
Reactome:REACT_89358 "Proteolysis of the IGF:IGFBP-3:ALS Complex by Thrombin, Bos taurus"
Reactome:REACT_89476 "Proteolysis of the IGF:IGFBP-3:ALS Complex by Plasmin, Bos taurus"
Reactome:REACT_92110 "plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [one-chain] catalyst), Sus scrofa"
Reactome:REACT_97801 "crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin, Sus scrofa"
GO:0004300 : enoyl-CoA hydratase activity
xref
Reactome:REACT_34688 "trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA, Escherichia coli"
Reactome:REACT_51199 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Bos taurus"
Reactome:REACT_77517 "trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA, Escherichia coli"
xref
Reactome:REACT_99776 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Bos taurus"
GO:0004304 : estrone sulfotransferase activity
xref
Reactome:REACT_113027 "estrone + PAPS => estrone 3-sulfate + PAP, Gallus gallus"
GO:0004310 : farnesyl-diphosphate farnesyltransferase activity
xref
Reactome:REACT_112589 "Two FPP molecules dimerize to form presqualene diphosphate, Xenopus tropicalis"
Reactome:REACT_112901 "Reduction of presqualene diphosphate to form squalene, Xenopus tropicalis"
GO:0004312 : fatty acid synthase activity
xref
Reactome:REACT_112198 "acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O, Mycobacterium tuberculosis"
Reactome:REACT_113128 "acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O, Dictyostelium discoideum"
GO:0004325 : ferrochelatase activity
xref
Reactome:REACT_31452 "Ferrous iron is inserted into protoporphyrin IX to form heme, Schizosaccharomyces pombe"
Reactome:REACT_86629 "Ferrous iron is inserted into protoporphyrin IX to form heme, Dictyostelium discoideum"
Reactome:REACT_98040 "Ferrous iron is inserted into protoporphyrin IX to form heme, Saccharomyces cerevisiae"
xref
Reactome:REACT_102151 "Ferrous iron is inserted into protoporphyrin IX to form heme, Schizosaccharomyces pombe"
Reactome:REACT_113497 "Ferrous iron is inserted into protoporphyrin IX to form heme, Oryza sativa"
Reactome:REACT_115167 "Ferrous iron is inserted into protoporphyrin IX to form heme, Arabidopsis thaliana"
Reactome:REACT_78000 "Ferrous iron is inserted into protoporphyrin IX to form heme, Dictyostelium discoideum"
Reactome:REACT_96094 "Ferrous iron is inserted into protoporphyrin IX to form heme, Saccharomyces cerevisiae"
GO:0004326 : tetrahydrofolylpolyglutamate synthase activity
xref
Reactome:REACT_107948 "Conversion of cytosolic THF to THF-polyglutamate, Schizosaccharomyces pombe"
Reactome:REACT_110751 "Conversion of cytosolic THF to THF-polyglutamate, Caenorhabditis elegans"
Reactome:REACT_93958 "Conversion of mitochondrial THF to THF-polyglutamate, Bos taurus"
Reactome:REACT_97478 "Conversion of mitochondrial THF to THF-polyglutamate, Sus scrofa"
xref
Reactome:REACT_104661 "Conversion of cytosolic THF to THF-polyglutamate, Caenorhabditis elegans"
Reactome:REACT_109341 "Conversion of cytosolic THF to THF-polyglutamate, Schizosaccharomyces pombe"
Reactome:REACT_78566 "Conversion of mitochondrial THF to THF-polyglutamate, Bos taurus"
Reactome:REACT_83339 "Conversion of mitochondrial THF to THF-polyglutamate, Sus scrofa"
GO:0004329 : formate-tetrahydrofolate ligase activity
xref
Reactome:REACT_101809 "THF polyglutamate + formate + ATP => 10-formylTHF polyglutamate + ADP + orthophosphate, Arabidopsis thaliana"
Reactome:REACT_28707 "THF polyglutamate + formate + ATP => 10-formylTHF polyglutamate + ADP + orthophosphate, Escherichia coli"
Reactome:REACT_33036 "THF polyglutamate + formate + ATP => 10-formylTHF polyglutamate + ADP + orthophosphate, Oryza sativa"
Reactome:REACT_33725 "THF polyglutamate + formate + ATP => 10-formylTHF polyglutamate + ADP + orthophosphate, Dictyostelium discoideum"
Reactome:REACT_82353 "THF polyglutamate + formate + ATP => 10-formylTHF polyglutamate + ADP + orthophosphate, Sus scrofa"
Reactome:REACT_89786 "THF polyglutamate + formate + ATP => 10-formylTHF polyglutamate + ADP + orthophosphate, Staphylococcus aureus N315"
Reactome:REACT_91991 "THF polyglutamate + formate + ATP => 10-formylTHF polyglutamate + ADP + orthophosphate, Caenorhabditis elegans"
xref
Reactome:REACT_112991 "THF polyglutamate + formate + ATP => 10-formylTHF polyglutamate + ADP + orthophosphate, Xenopus tropicalis"
Reactome:REACT_84185 "THF polyglutamate + formate + ATP => 10-formylTHF polyglutamate + ADP + orthophosphate, Sus scrofa"
GO:0004331 : fructose-2,6-bisphosphate 2-phosphatase activity
xref
Reactome:REACT_34437 "Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate, Saccharomyces cerevisiae"
xref
Reactome:REACT_102107 "Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate, Saccharomyces cerevisiae"
Reactome:REACT_113676 "Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate, Gallus gallus"
GO:0004332 : fructose-bisphosphate aldolase activity
xref
Reactome:REACT_32660 "D-fructose 1-phosphate <=> D-glyceraldehyde + dihydroxyacetone phosphate, Dictyostelium discoideum"
Reactome:REACT_80137 "dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate <=> D-fructose 1,6-bisphosphate, Plasmodium falciparum"
xref
Reactome:REACT_80109 "D-fructose 1-phosphate <=> D-glyceraldehyde + dihydroxyacetone phosphate, Dictyostelium discoideum"
Reactome:REACT_88447 "dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate <=> D-fructose 1,6-bisphosphate, Plasmodium falciparum"
GO:0004333 : fumarate hydratase activity
xref
Reactome:REACT_115295 "Fumarate + H2O <=> (S)-Malate, Xenopus tropicalis"
GO:0004334 : fumarylacetoacetase activity
xref
Reactome:REACT_108367 "fumarylacetoacetate => fumarate + acetoacetate, Sus scrofa"
xref
Reactome:REACT_105315 "fumarylacetoacetate => fumarate + acetoacetate, Sus scrofa"
GO:0004335 : galactokinase activity
xref
Reactome:REACT_113809 "ATP + D-galactose => ADP + D-galactose 1-phosphate, Mycobacterium tuberculosis"
GO:0004336 : galactosylceramidase activity
synonym
"galactocerebroside.beta-galactosidase activity" EXACT [EC:3.2.1.46]
"galactosylceramide.beta-galactosidase activity" EXACT [EC:3.2.1.46]
GO:0004338 : glucan exo-1,3-beta-glucosidase activity
def
Catalysis of the successive hydrolysis of beta-D-glucose units from the non-reducing ends of 1,3-beta-D-glucans, releasing alpha-glucose.
def
Catalysis of the successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose.
GO:0004339 : glucan 1,4-alpha-glucosidase activity
def
Catalysis of the hydrolysis of terminal 1,4-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose.
def
Catalysis of the hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose.
GO:0004340 : glucokinase activity
xref
Reactome:REACT_31874 "alpha-D-Glucose + ATP => alpha-D-glucose 6-phosphate + ADP, Drosophila melanogaster"
Reactome:REACT_81299 "alpha-D-Glucose + ATP => alpha-D-glucose 6-phosphate + ADP, Sus scrofa"
Reactome:REACT_96972 "alpha-D-Glucose + ATP => alpha-D-glucose 6-phosphate + ADP, Saccharomyces cerevisiae"
xref
Reactome:REACT_109618 "alpha-D-Glucose + ATP => alpha-D-glucose 6-phosphate + ADP, Sus scrofa"
Reactome:REACT_90073 "alpha-D-Glucose + ATP => alpha-D-glucose 6-phosphate + ADP, Saccharomyces cerevisiae"
GO:0004345 : glucose-6-phosphate dehydrogenase activity
xref
Reactome:REACT_112685 "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+, Plasmodium falciparum"
Reactome:REACT_114196 "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+, Xenopus tropicalis"
Reactome:REACT_114740 "alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+, Dictyostelium discoideum"
GO:0004347 : glucose-6-phosphate isomerase activity
xref
Reactome:REACT_107487 "D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate, Schizosaccharomyces pombe"
xref
Reactome:REACT_103273 "D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate, Schizosaccharomyces pombe"
Reactome:REACT_113483 "alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate, Arabidopsis thaliana"
Reactome:REACT_115143 "D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate, Arabidopsis thaliana"
GO:0004353 : glutamate dehydrogenase [NAD(P)+] activity
xref
Reactome:REACT_81956 "alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1], Sus scrofa"
Reactome:REACT_82949 "alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1], Bos taurus"
Reactome:REACT_88656 "alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1], Rattus norvegicus"
Reactome:REACT_90311 "glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1], Bos taurus"
Reactome:REACT_97135 "glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1], Rattus norvegicus"
Reactome:REACT_97307 "glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1], Sus scrofa"
xref
Reactome:REACT_112437 "alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1], Canis familiaris"
Reactome:REACT_112733 "alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1], Staphylococcus aureus N315"
Reactome:REACT_113249 "glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1], Staphylococcus aureus N315"
Reactome:REACT_114470 "glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1], Canis familiaris"
GO:0004356 : glutamate-ammonia ligase activity
xref
Reactome:REACT_112105 "glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL], Oryza sativa"
Reactome:REACT_115035 "glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL], Arabidopsis thaliana"
GO:0004359 : glutaminase activity
xref
Reactome:REACT_77355 "glutamine + H2O => glutamate + NH4+ [GLS], Bos taurus"
xref
Reactome:REACT_108874 "glutamine + H2O => glutamate + NH4+ [GLS], Bos taurus"
GO:0004361 : glutaryl-CoA dehydrogenase activity
xref
Reactome:REACT_106441 "glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2, Sus scrofa"
xref
Reactome:REACT_110967 "glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2, Sus scrofa"
GO:0004362 : glutathione-disulfide reductase activity
xref
Reactome:REACT_101227 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+, Arabidopsis thaliana"
Reactome:REACT_96541 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+, Oryza sativa"
GO:0004363 : glutathione synthase activity
xref
Reactome:REACT_100506 "gamma-glutamylcysteine combines with glycine to form glutathione, Saccharomyces cerevisiae"
xref
Reactome:REACT_104397 "gamma-glutamylcysteine combines with glycine to form glutathione, Saccharomyces cerevisiae"
GO:0004364 : glutathione transferase activity
xref
Reactome:REACT_113981 "Glutathione conjugation of cytosolic substrates, Oryza sativa"
Reactome:REACT_114178 "Glutathione conjugation of luminal substrates, Plasmodium falciparum"
Reactome:REACT_114437 "Glutathione conjugation of cytosolic substrates, Arabidopsis thaliana"
Reactome:REACT_114776 "Glutathione conjugation of cytosolic substrates, Plasmodium falciparum"
GO:0004365 : glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
xref
Reactome:REACT_78137 "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+, Caenorhabditis elegans"
Reactome:REACT_98912 "D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+, Dictyostelium discoideum"
xref
Reactome:REACT_112334 "D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+, Oryza sativa"
Reactome:REACT_112690 "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+, Drosophila melanogaster"
Reactome:REACT_112805 "D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+, Arabidopsis thaliana"
Reactome:REACT_113461 "D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+, Drosophila melanogaster"
Reactome:REACT_113644 "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+, Xenopus tropicalis"
Reactome:REACT_113850 "D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+, Plasmodium falciparum"
Reactome:REACT_114520 "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+, Plasmodium falciparum"
Reactome:REACT_115033 "D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+, Xenopus tropicalis"
Reactome:REACT_115268 "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+, Oryza sativa"
Reactome:REACT_115436 "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+, Arabidopsis thaliana"
Reactome:REACT_32485 "1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+, Caenorhabditis elegans"
Reactome:REACT_80434 "D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+, Dictyostelium discoideum"
GO:0004366 : glycerol-3-phosphate O-acyltransferase activity
xref
Reactome:REACT_34083 "glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [ER membrane-associated], Sus scrofa"
xref
Reactome:REACT_112568 "glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated], Escherichia coli"
Reactome:REACT_113073 "glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated], Mycobacterium tuberculosis"
Reactome:REACT_114086 "glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [ER membrane-associated], Arabidopsis thaliana"
Reactome:REACT_114724 "glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [ER membrane-associated], Dictyostelium discoideum"
Reactome:REACT_32967 "glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [ER membrane-associated], Sus scrofa"
GO:0004367 : glycerol-3-phosphate dehydrogenase [NAD+] activity
xref
Reactome:REACT_33567 "Conversion of Dihydroxyacetone Phosphate to Glycerol -3- phosphate, Oryza sativa"
Reactome:REACT_79099 "Conversion of Dihydroxyacetone Phosphate to Glycerol -3- phosphate, Drosophila melanogaster"
Reactome:REACT_96383 "Conversion of Dihydroxyacetone Phosphate to Glycerol -3- phosphate, Arabidopsis thaliana"
xref
Reactome:REACT_113156 "Conversion of Dihydroxyacetone Phosphate to Glycerol -3- phosphate, Danio rerio"
Reactome:REACT_115427 "Conversion of Dihydroxyacetone Phosphate to Glycerol -3- phosphate, Caenorhabditis elegans"
GO:0004368 : glycerol-3-phosphate dehydrogenase activity
xref
Reactome:REACT_107630 "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase), Schizosaccharomyces pombe"
Reactome:REACT_77366 "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase), Saccharomyces cerevisiae"
xref
Reactome:REACT_104083 "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase), Saccharomyces cerevisiae"
Reactome:REACT_112809 "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase), Mycobacterium tuberculosis"
Reactome:REACT_114651 "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase), Caenorhabditis elegans"
Reactome:REACT_115394 "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase), Drosophila melanogaster"
Reactome:REACT_77515 "Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase), Schizosaccharomyces pombe"
GO:0004372 : glycine hydroxymethyltransferase activity
xref
Reactome:REACT_34625 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Saccharomyces cerevisiae"
Reactome:REACT_79534 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Caenorhabditis elegans"
xref
Reactome:REACT_110497 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Saccharomyces cerevisiae"
Reactome:REACT_112625 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Mycobacterium tuberculosis"
Reactome:REACT_112714 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Staphylococcus aureus N315"
Reactome:REACT_113302 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Escherichia coli"
Reactome:REACT_113467 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Escherichia coli"
Reactome:REACT_114244 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Escherichia coli"
Reactome:REACT_114305 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Staphylococcus aureus N315"
Reactome:REACT_114385 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Staphylococcus aureus N315"
Reactome:REACT_114576 "Tetrahydrofolate polyglutamate (THF polyglutamate) + serine <=> 5,10-methyleneTHF polyglutamate + glycine, Mycobacterium tuberculosis"
Reactome:REACT_115121 "5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine, Mycobacterium tuberculosis"
Reactome:REACT_91776 "beta-hydroxy-trimethyllysine => gamma-butyrobetaine aldehyde + glycine, Caenorhabditis elegans"
GO:0004373 : glycogen (starch) synthase activity
xref
Reactome:REACT_89752 "8 UDP-glucose + ((1,4)-alpha-D-glucosyl)4 glycogenin => 8 UDP + ((1,4)-alpha-D-glucosyl)8 glycogenin [GYS D form], Bos taurus"
xref
Reactome:REACT_101890 "8 UDP-glucose + ((1,4)-alpha-D-glucosyl)4 glycogenin => 8 UDP + ((1,4)-alpha-D-glucosyl)8 glycogenin [GYS D form], Bos taurus"
GO:0004376 : glycolipid mannosyltransferase activity
xref
Reactome:REACT_100815 "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate, Saccharomyces cerevisiae"
Reactome:REACT_29714 "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate, Saccharomyces cerevisiae"
Reactome:REACT_77543 "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate, Sus scrofa"
Reactome:REACT_90925 "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate, Sus scrofa"
xref
Reactome:REACT_101404 "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate, Saccharomyces cerevisiae"
Reactome:REACT_111941 "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate, Xenopus tropicalis"
Reactome:REACT_78709 "mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate, Sus scrofa"
Reactome:REACT_78994 "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate, Sus scrofa"
Reactome:REACT_89761 "(ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate, Saccharomyces cerevisiae"
GO:0004377 : GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity
name
glycolipid 2-alpha-mannosyltransferase activity
def
Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-1,2-D-mannosyl-D-mannose linkage.
name
GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity
def
Catalysis of the reaction: an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP + 2 H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage.
synonym
"GDP-D-mannose:D-Man-alpha-(1->3)-[D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,2-mannosyltransferase activity" EXACT [EC:2.4.1.131]
"glycolipid 2-alpha-mannosyltransferase activity" EXACT [EC:2.4.1.131]
GO:0004378 : GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity
name
glycolipid 3-alpha-mannosyltransferase activity
def
Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-1,3-D-mannosyl-D-mannose linkage.
name
GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity
def
Catalysis of the reaction: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose = alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP + H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->3)-D-mannosyl-D-mannose linkage.
synonym
"GDP-D-mannose:D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol 3-alpha-mannosyltransferase activity" EXACT systematic_synonym [EC:2.4.1.132]
"glycolipid 3-alpha-mannosyltransferase activity" EXACT [EC:2.4.1.132]
GO:0004381 : fucosylgalactoside 3-alpha-galactosyltransferase activity
synonym
"UDP-galactose:alpha-L-fucosyl-(1,2)-D-galactoside 3-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.37]
"UDPgalactose:alpha-L-fucosyl-(1,2)-D-galactoside 3-alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.37]
"UDPgalactose:O-alpha-L-fucosyl(1,2)D-galactose alpha-D-galactosyltransferase activity" EXACT [EC:2.4.1.37]
GO:0004383 : guanylate cyclase activity
xref
Reactome:REACT_115231 "Soluble guanylate cyclase converts GTP to cGMP, Dictyostelium discoideum"
Reactome:REACT_115362 "Soluble guanylate cyclase converts GTP to cGMP, Mycobacterium tuberculosis"
GO:0004385 : guanylate kinase activity
xref
Reactome:REACT_100024 "(d)GMP + ATP <=> (d)GDP + ADP [GUK1], Saccharomyces cerevisiae"
Reactome:REACT_110329 "(d)GMP + ATP <=> (d)GDP + ADP [GUK1], Caenorhabditis elegans"
Reactome:REACT_31701 "(d)GMP + ATP <=> (d)GDP + ADP [GUK1], Mycobacterium tuberculosis"
Reactome:REACT_32327 "(d)GDP + ADP <=> (d)GMP + ATP [GUK1], Mycobacterium tuberculosis"
Reactome:REACT_92553 "(d)GDP + ADP <=> (d)GMP + ATP [GUK1], Saccharomyces cerevisiae"
xref
Reactome:REACT_112127 "(d)GMP + ATP <=> (d)GDP + ADP [GUK1], Oryza sativa"
Reactome:REACT_114888 "(d)GDP + ADP <=> (d)GMP + ATP [GUK1], Oryza sativa"
Reactome:REACT_115196 "(d)GDP + ADP <=> (d)GMP + ATP [GUK1], Arabidopsis thaliana"
Reactome:REACT_115456 "(d)GMP + ATP <=> (d)GDP + ADP [GUK1], Arabidopsis thaliana"
Reactome:REACT_31346 "(d)GMP + ATP <=> (d)GDP + ADP [GUK1], Caenorhabditis elegans"
GO:0004386 : helicase activity
xref
Reactome:REACT_100335 "RNA Polymerase II Promoter Opening: First Transition, Dictyostelium discoideum"
Reactome:REACT_102116 "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Bos taurus"
Reactome:REACT_110838 "Addition of the third nucleotide on the nascent transcript, Bos taurus"
Reactome:REACT_79401 "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Schizosaccharomyces pombe"
Reactome:REACT_88953 "Addition of the third nucleotide on the nascent transcript, Canis familiaris"
Reactome:REACT_91596 "RNA Polymerase II Promoter Opening: First Transition, Canis familiaris"
Reactome:REACT_91692 "RNA Polymerase II Promoter Opening: First Transition, Bos taurus"
Reactome:REACT_93046 "Cap-bound mRNA is activated by helicases, Rattus norvegicus"
Reactome:REACT_99106 "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Canis familiaris"
xref
Reactome:REACT_103881 "RNA Polymerase II Promoter Opening: First Transition, Dictyostelium discoideum"
Reactome:REACT_112208 "MCM8 mediated fork unwinding, Drosophila melanogaster"
Reactome:REACT_112817 "Cap-bound mRNA is activated by helicases, Schizosaccharomyces pombe"
Reactome:REACT_113177 "Formation of open bubble structure in DNA by helicases, Caenorhabditis elegans"
Reactome:REACT_31554 "Addition of the fourth nucleotide on the Nascent Transcript: Second Transition, Schizosaccharomyces pombe"
GO:0004415 : hyalurononglucosaminidase activity
def
Catalysis of the random hydrolysis of 1,4-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.
def
Catalysis of the random hydrolysis of (1->4) linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.
GO:0004418 : hydroxymethylbilane synthase activity
xref
Reactome:REACT_111975 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Bos taurus"
Reactome:REACT_112064 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Mycobacterium tuberculosis"
Reactome:REACT_112125 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Xenopus tropicalis"
Reactome:REACT_112182 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Saccharomyces cerevisiae"
Reactome:REACT_112379 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Gallus gallus"
Reactome:REACT_112891 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Danio rerio"
Reactome:REACT_112987 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Escherichia coli"
Reactome:REACT_113671 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Dictyostelium discoideum"
Reactome:REACT_113741 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Oryza sativa"
Reactome:REACT_113842 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Schizosaccharomyces pombe"
Reactome:REACT_113975 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Arabidopsis thaliana"
Reactome:REACT_113989 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Mus musculus"
Reactome:REACT_114353 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Rattus norvegicus"
Reactome:REACT_114418 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Staphylococcus aureus N315"
Reactome:REACT_114514 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Plasmodium falciparum"
Reactome:REACT_114679 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Drosophila melanogaster"
Reactome:REACT_114680 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Sus scrofa"
Reactome:REACT_115346 "Four PBGs combine through deamination to form hydroxymethylbilane (HMB), Canis familiaris"
GO:0004419 : hydroxymethylglutaryl-CoA lyase activity
xref
Reactome:REACT_100202 "HMG CoA => acetoacetic acid+ acetyl CoA, Dictyostelium discoideum"
Reactome:REACT_104457 "HMG CoA => acetoacetic acid+ acetyl CoA, Drosophila melanogaster"
Reactome:REACT_105243 "HMG CoA => acetoacetic acid+ acetyl CoA, Canis familiaris"
Reactome:REACT_108952 "HMG CoA => acetoacetic acid+ acetyl CoA, Gallus gallus"
Reactome:REACT_110966 "HMG CoA => acetoacetic acid+ acetyl CoA, Arabidopsis thaliana"
Reactome:REACT_2103 "HMG CoA => acetoacetic acid+ acetyl CoA, Homo sapiens"
Reactome:REACT_29720 "HMG CoA => acetoacetic acid+ acetyl CoA, Oryza sativa"
Reactome:REACT_31175 "HMG CoA => acetoacetic acid+ acetyl CoA, Taeniopygia guttata"
Reactome:REACT_86954 "HMG CoA => acetoacetic acid+ acetyl CoA, Mus musculus"
Reactome:REACT_89460 "HMG CoA => acetoacetic acid+ acetyl CoA, Xenopus tropicalis"
Reactome:REACT_90800 "HMG CoA => acetoacetic acid+ acetyl CoA, Rattus norvegicus"
Reactome:REACT_91737 "HMG CoA => acetoacetic acid+ acetyl CoA, Bos taurus"
Reactome:REACT_99837 "HMG CoA => acetoacetic acid+ acetyl CoA, Danio rerio"
Reactome:REACT_99898 "HMG CoA => acetoacetic acid+ acetyl CoA, Caenorhabditis elegans"
xref
Reactome:REACT_100202 "HMG CoA => acetoacetic acid + acetyl CoA, Dictyostelium discoideum"
Reactome:REACT_104457 "HMG CoA => acetoacetic acid + acetyl CoA, Drosophila melanogaster"
Reactome:REACT_105243 "HMG CoA => acetoacetic acid + acetyl CoA, Canis familiaris"
Reactome:REACT_108952 "HMG CoA => acetoacetic acid + acetyl CoA, Gallus gallus"
Reactome:REACT_110966 "HMG CoA => acetoacetic acid + acetyl CoA, Arabidopsis thaliana"
Reactome:REACT_2103 "HMG CoA => acetoacetic acid + acetyl CoA, Homo sapiens"
Reactome:REACT_29720 "HMG CoA => acetoacetic acid + acetyl CoA, Oryza sativa"
Reactome:REACT_31175 "HMG CoA => acetoacetic acid + acetyl CoA, Taeniopygia guttata"
Reactome:REACT_86954 "HMG CoA => acetoacetic acid + acetyl CoA, Mus musculus"
Reactome:REACT_89460 "HMG CoA => acetoacetic acid + acetyl CoA, Xenopus tropicalis"
Reactome:REACT_90800 "HMG CoA => acetoacetic acid + acetyl CoA, Rattus norvegicus"
Reactome:REACT_91737 "HMG CoA => acetoacetic acid + acetyl CoA, Bos taurus"
Reactome:REACT_99837 "HMG CoA => acetoacetic acid + acetyl CoA, Danio rerio"
Reactome:REACT_99898 "HMG CoA => acetoacetic acid + acetyl CoA, Caenorhabditis elegans"
GO:0004421 : hydroxymethylglutaryl-CoA synthase activity
xref
Reactome:REACT_103557 "acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH, Caenorhabditis elegans"
Reactome:REACT_81885 "Condensation of acetyl CoA with acetoacetyl CoA to form HMG-CoA, Caenorhabditis elegans"
GO:0004427 : inorganic diphosphatase activity
xref
Reactome:REACT_96188 "pyrophosphate + H2O => 2 orthophosphate [cytosolic], Caenorhabditis elegans"
xref
Reactome:REACT_113089 "pyrophosphate + H2O => 2 orthophosphate [cytosolic], Arabidopsis thaliana"
Reactome:REACT_113725 "pyrophosphate + H2O => 2 orthophosphate [cytosolic], Mycobacterium tuberculosis"
Reactome:REACT_114811 "pyrophosphate + H2O => 2 orthophosphate [cytosolic], Oryza sativa"
Reactome:REACT_115460 "pyrophosphate + H2O => 2 orthophosphate [cytosolic], Plasmodium falciparum"
Reactome:REACT_95722 "pyrophosphate + H2O => 2 orthophosphate [cytosolic], Caenorhabditis elegans"
GO:0004428 : inositol or phosphatidylinositol kinase activity
def
Catalysis of the phosphorylation of myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol.
subset
gosubset_prok
is_a
GO:0016301
def
OBSOLETE. Catalysis of the phosphorylation of myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol.
comment
This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids.
is_obsolete
true
consider
GO:0016307
GO:0019140
GO:0052742
GO:0052813
GO:0004435 : phosphatidylinositol phospholipase C activity
xref
Reactome:REACT_16916 "PLC-gamma hydrolyses PIP2, Homo sapiens"
Reactome:REACT_33727 "PIP2 hydrolysis, Sus scrofa"
Reactome:REACT_40672 "PLC-gamma hydrolyses PIP2, Canis familiaris"
Reactome:REACT_47190 "PLC-gamma hydrolyses PIP2, Bos taurus"
Reactome:REACT_73633 "PLC-gamma hydrolyses PIP2, Gallus gallus"
Reactome:REACT_78307 "PLC-gamma hydrolyses PIP2, Rattus norvegicus"
Reactome:REACT_83793 "PLC-gamma hydrolyses PIP2, Mus musculus"
Reactome:REACT_88110 "PLC-gamma hydrolyses PIP2, Drosophila melanogaster"
Reactome:REACT_94157 "PLC-gamma hydrolyses PIP2, Danio rerio"
Reactome:REACT_96001 "PLC-gamma hydrolyses PIP2, Sus scrofa"
Reactome:REACT_96266 "PLC-gamma hydrolyses PIP2, Xenopus tropicalis"
Reactome:REACT_98027 "PLC-gamma hydrolyses PIP2, Taeniopygia guttata"
xref
Reactome:REACT_111977 "PIP2 hydrolysis, Drosophila melanogaster"
Reactome:REACT_112016 "Active PLCG1 hydrolyses PIP2, Arabidopsis thaliana"
Reactome:REACT_112120 "PLC-gamma1 hydrolyses PIP2, Saccharomyces cerevisiae"
Reactome:REACT_112432 "PLC-gamma1 hydrolyses PIP2, Oryza sativa"
Reactome:REACT_112586 "PIP2 hydrolysis, Oryza sativa"
Reactome:REACT_113026 "PLC-gamma1 hydrolyses PIP2, Drosophila melanogaster"
Reactome:REACT_113134 "PIP2 hydrolysis, Schizosaccharomyces pombe"
Reactome:REACT_113176 "PLC-gamma1 hydrolyses PIP2, Arabidopsis thaliana"
Reactome:REACT_113179 "Active PLCG1 hydrolyses PIP2, Saccharomyces cerevisiae"
Reactome:REACT_113201 "PLC-gamma1 hydrolyses PIP2, Plasmodium falciparum"
Reactome:REACT_113580 "PLC-gamma1 hydrolyses PIP2, Dictyostelium discoideum"
Reactome:REACT_113618 "Active PLCG1 hydrolyses PIP2, Plasmodium falciparum"
Reactome:REACT_113733 "Active PLCG1 hydrolyses PIP2, Dictyostelium discoideum"
Reactome:REACT_113827 "PIP2 hydrolysis, Dictyostelium discoideum"
Reactome:REACT_113870 "PLC-gamma1 hydrolyses PIP2, Schizosaccharomyces pombe"
Reactome:REACT_113925 "Active PLCG1 hydrolyses PIP2, Drosophila melanogaster"
Reactome:REACT_113959 "PIP2 hydrolysis, Arabidopsis thaliana"
Reactome:REACT_114034 "PIP2 hydrolysis, Schizosaccharomyces pombe"
Reactome:REACT_114083 "Active PLCG1 hydrolyses PIP2, Oryza sativa"
Reactome:REACT_114101 "PLC-gamma1 hydrolyses PIP2, Caenorhabditis elegans"
Reactome:REACT_114237 "Active PLCG1 hydrolyses PIP2, Caenorhabditis elegans"
Reactome:REACT_114264 "Active PLCG1 hydrolyses PIP2, Schizosaccharomyces pombe"
Reactome:REACT_114329 "PIP2 hydrolysis, Dictyostelium discoideum"
Reactome:REACT_114608 "PIP2 hydrolysis, Saccharomyces cerevisiae"
Reactome:REACT_114663 "PIP2 hydrolysis, Plasmodium falciparum"
Reactome:REACT_114783 "PIP2 hydrolysis, Caenorhabditis elegans"
Reactome:REACT_115119 "PIP2 hydrolysis, Saccharomyces cerevisiae"
Reactome:REACT_90807 "PIP2 hydrolysis, Sus scrofa"
GO:0004437 : inositol or phosphatidylinositol phosphatase activity
def
Catalysis of the removal of a phosphate group from phosphorylated myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol.
subset
gosubset_prok
is_a
GO:0016791
def
OBSOLETE. Catalysis of the removal of a phosphate group from phosphorylated myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol.
comment
This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids.
is_obsolete
true
consider
GO:0034593
GO:0034594
GO:0052744
GO:0052745
GO:0004449 : isocitrate dehydrogenase (NAD+) activity
xref
Reactome:REACT_112010 "isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3], Bos taurus"
Reactome:REACT_113241 "isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3], Canis familiaris"
GO:0004450 : isocitrate dehydrogenase (NADP+) activity
xref
Reactome:REACT_112251 "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+, Plasmodium falciparum"
Reactome:REACT_112495 "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+, Oryza sativa"
Reactome:REACT_113535 "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+, Arabidopsis thaliana"
Reactome:REACT_114848 "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+, Arabidopsis thaliana"
Reactome:REACT_115223 "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+, Plasmodium falciparum"
Reactome:REACT_115270 "isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+, Oryza sativa"
GO:0004452 : isopentenyl-diphosphate delta-isomerase activity
synonym
"ipp isomerase activity" EXACT [EC:5.3.3.2]
"isopentenylpyrophosphate Delta-isomerase activity" EXACT [EC:5.3.3.2]
GO:0004459 : L-lactate dehydrogenase activity
xref
Reactome:REACT_44482 "Pyruvate + NADH + H+ <=> (S)-Lactate + NAD+, Plasmodium falciparum"
Reactome:REACT_79336 "(S)-Lactate + NAD+ <=> Pyruvate + NADH + H+, Plasmodium falciparum"
xref
Reactome:REACT_112284 "Pyruvate + NADH + H+ <=> (S)-Lactate + NAD+, Drosophila melanogaster"
Reactome:REACT_112343 "(S)-Lactate + NAD+ <=> Pyruvate + NADH + H+, Drosophila melanogaster"
Reactome:REACT_112780 "(S)-Lactate + NAD+ <=> Pyruvate + NADH + H+, Arabidopsis thaliana"
Reactome:REACT_112887 "Pyruvate + NADH + H+ <=> (S)-Lactate + NAD+, Arabidopsis thaliana"
Reactome:REACT_113309 "(S)-Lactate + NAD+ <=> Pyruvate + NADH + H+, Oryza sativa"
Reactome:REACT_113500 "Pyruvate + NADH + H+ <=> (S)-Lactate + NAD+, Oryza sativa"
Reactome:REACT_115097 "(S)-Lactate + NAD+ <=> Pyruvate + NADH + H+, Caenorhabditis elegans"
Reactome:REACT_115372 "Pyruvate + NADH + H+ <=> (S)-Lactate + NAD+, Caenorhabditis elegans"
GO:0004463 : leukotriene-A4 hydrolase activity
xref
Reactome:REACT_113583 "LTA4 is hydrolyzed to LTB4, Dictyostelium discoideum"
Reactome:REACT_113737 "LTA4 is hydrolyzed to LTB4, Mycobacterium tuberculosis"
Reactome:REACT_115125 "LTA4 is hydrolyzed to LTB4, Saccharomyces cerevisiae"
Reactome:REACT_115164 "LTA4 is hydrolyzed to LTB4, Schizosaccharomyces pombe"
GO:0004467 : long-chain fatty acid-CoA ligase activity
xref
Reactome:REACT_105550 "THCA is conjugated with Coenzyme A (SLC27A5 BACS), Sus scrofa"
Reactome:REACT_108001 "Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS), Sus scrofa"
Reactome:REACT_108128 "palmitate + CoASH + ATP => palmitoyl-CoA + AMP + pyrophosphate + H2O [ACSL5], Drosophila melanogaster"
Reactome:REACT_109703 "THCA is conjugated with Coenzyme A (SLC27A5 BACS), Bos taurus"
Reactome:REACT_88013 "TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS), Sus scrofa"
Reactome:REACT_88306 "palmitate + CoASH + ATP => palmitoyl-CoA + AMP + pyrophosphate + H2O [ACSL5], Arabidopsis thaliana"
Reactome:REACT_89029 "DHCA is conjugated with Coenzyme A (SLC27A5 BACS), Sus scrofa"
Reactome:REACT_92028 "3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS), Sus scrofa"
Reactome:REACT_93457 "palmitate + CoASH + ATP => palmitoyl-CoA + AMP + pyrophosphate + H2O [ACSL5], Oryza sativa"
xref
Reactome:REACT_100377 "THCA is conjugated with Coenzyme A (SLC27A5 BACS), Bos taurus"
Reactome:REACT_112002 "TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS), Saccharomyces cerevisiae"
Reactome:REACT_112185 "palmitate + CoASH + ATP => palmitoyl-CoA + AMP + pyrophosphate + H2O [ACSL3], Dictyostelium discoideum"
Reactome:REACT_112197 "palmitate + CoASH + ATP => palmitoyl-CoA + AMP + pyrophosphate + H2O [ACSL3], Mycobacterium tuberculosis"
Reactome:REACT_112234 "palmitate + CoASH + ATP => palmitoyl-CoA + AMP + pyrophosphate + H2O [ACSL5], Dictyostelium discoideum"
Reactome:REACT_112314 "3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS), Taeniopygia guttata"
Reactome:REACT_112696 "THCA is conjugated with Coenzyme A (SLC27A5 BACS), Saccharomyces cerevisiae"
Reactome:REACT_113165 "TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS), Saccharomyces cerevisiae"
Reactome:REACT_113283 "DHCA is conjugated with Coenzyme A (SLC27A2 VLCS), Saccharomyces cerevisiae"
Reactome:REACT_113402 "DHCA is conjugated with Coenzyme A (SLC27A2 VLCS), Taeniopygia guttata"
Reactome:REACT_113433 "palmitate + CoASH + ATP => palmitoyl-CoA + AMP + pyrophosphate + H2O [ACSL3], Plasmodium falciparum"
Reactome:REACT_113477 "Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS), Saccharomyces cerevisiae"
Reactome:REACT_113562 "DHCA is conjugated with Coenzyme A (SLC27A5 BACS), Saccharomyces cerevisiae"
Reactome:REACT_113604 "TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS), Taeniopygia guttata"
Reactome:REACT_114408 "3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS), Saccharomyces cerevisiae"
Reactome:REACT_114641 "3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS), Saccharomyces cerevisiae"
Reactome:REACT_114941 "THCA is conjugated with Coenzyme A (SLC27A2 VLCS), Saccharomyces cerevisiae"
Reactome:REACT_115449 "THCA is conjugated with Coenzyme A (SLC27A2 VLCS), Taeniopygia guttata"
Reactome:REACT_115464 "palmitate + CoASH + ATP => palmitoyl-CoA + AMP + pyrophosphate + H2O [ACSL3], Xenopus tropicalis"
GO:0004477 : methenyltetrahydrofolate cyclohydrolase activity
xref
Reactome:REACT_102452 "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate, Saccharomyces cerevisiae"
Reactome:REACT_106007 "10-formylTHF polyglutamate <=> 5,10-methenylTHF polyglutamate + H2O, Escherichia coli"
Reactome:REACT_106128 "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate, Dictyostelium discoideum"
Reactome:REACT_29810 "10-formylTHF polyglutamate <=> 5,10-methenylTHF polyglutamate + H2O, Oryza sativa"
Reactome:REACT_30136 "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate, Arabidopsis thaliana"
Reactome:REACT_32385 "10-formylTHF polyglutamate <=> 5,10-methenylTHF polyglutamate + H2O, Caenorhabditis elegans"
Reactome:REACT_33047 "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate, Oryza sativa"
Reactome:REACT_77264 "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate, Staphylococcus aureus N315"
Reactome:REACT_78768 "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate, Escherichia coli"
Reactome:REACT_84517 "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate, Caenorhabditis elegans"
Reactome:REACT_92875 "10-formylTHF polyglutamate <=> 5,10-methenylTHF polyglutamate + H2O, Arabidopsis thaliana"
Reactome:REACT_94612 "10-formylTHF polyglutamate <=> 5,10-methenylTHF polyglutamate + H2O, Dictyostelium discoideum"
Reactome:REACT_96618 "10-formylTHF polyglutamate <=> 5,10-methenylTHF polyglutamate + H2O, Staphylococcus aureus N315"
xref
Reactome:REACT_100157 "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate, Saccharomyces cerevisiae"
Reactome:REACT_112952 "5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate, Xenopus tropicalis"
Reactome:REACT_114540 "10-formylTHF polyglutamate <=> 5,10-methenylTHF polyglutamate + H2O, Xenopus tropicalis"
GO:0004478 : methionine adenosyltransferase activity
xref
Reactome:REACT_106475 "SAM is sythesized from methionine's reaction with ATP, Dictyostelium discoideum"
Reactome:REACT_33958 "SAM is sythesized from methionine's reaction with ATP, Oryza sativa"
Reactome:REACT_34627 "SAM is sythesized from methionine's reaction with ATP, Plasmodium falciparum"
Reactome:REACT_79723 "SAM is sythesized from methionine's reaction with ATP, Arabidopsis thaliana"
Reactome:REACT_93771 "SAM is sythesized from methionine's reaction with ATP, Saccharomyces cerevisiae"
xref
Reactome:REACT_115032 "SAM is sythesized from methionine's reaction with ATP, Staphylococcus aureus N315"
Reactome:REACT_77762 "SAM is sythesized from methionine's reaction with ATP, Saccharomyces cerevisiae"
GO:0004482 : mRNA (guanine-N7-)-methyltransferase activity
xref
Reactome:REACT_108598 "Methylation of GMP-cap by RNA Methyltransferase, Canis familiaris"
Reactome:REACT_94906 "Methylation of GMP-cap by RNA Methyltransferase, Bos taurus"
GO:0004484 : mRNA guanylyltransferase activity
xref
Reactome:REACT_97660 "Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA, Saccharomyces cerevisiae"
xref
Reactome:REACT_88083 "Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA, Saccharomyces cerevisiae"
GO:0004485 : methylcrotonoyl-CoA carboxylase activity
xref
Reactome:REACT_112537 "beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA], Mycobacterium tuberculosis"
GO:0004486 : methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity
xref
Reactome:REACT_102502 "5,10-methenylTHF polyglutamate + NADPH + H+ <=> 5,10-methyleneTHF polyglutamate + NADP+, Caenorhabditis elegans"
Reactome:REACT_103459 "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+, Escherichia coli"
Reactome:REACT_109615 "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+, Arabidopsis thaliana"
Reactome:REACT_32157 "5,10-methenylTHF polyglutamate + NADPH + H+ <=> 5,10-methyleneTHF polyglutamate + NADP+, Oryza sativa"
Reactome:REACT_33699 "5,10-methenylTHF polyglutamate + NADPH + H+ <=> 5,10-methyleneTHF polyglutamate + NADP+, Arabidopsis thaliana"
Reactome:REACT_79429 "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+, Sus scrofa"
Reactome:REACT_79552 "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+, Caenorhabditis elegans"
Reactome:REACT_81578 "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+, Oryza sativa"
Reactome:REACT_85524 "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+, Dictyostelium discoideum"
Reactome:REACT_87536 "5,10-methenylTHF polyglutamate + NADPH + H+ <=> 5,10-methyleneTHF polyglutamate + NADP+, Staphylococcus aureus N315"
Reactome:REACT_89320 "5,10-methenylTHF polyglutamate + NADPH + H+ <=> 5,10-methyleneTHF polyglutamate + NADP+, Dictyostelium discoideum"
Reactome:REACT_91104 "5,10-methenylTHF polyglutamate + NADPH + H+ <=> 5,10-methyleneTHF polyglutamate + NADP+, Sus scrofa"
Reactome:REACT_92013 "5,10-methenylTHF polyglutamate + NADPH + H+ <=> 5,10-methyleneTHF polyglutamate + NADP+, Escherichia coli"
Reactome:REACT_99867 "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+, Staphylococcus aureus N315"
xref
Reactome:REACT_112142 "5,10-methenylTHF polyglutamate + NADPH + H+ <=> 5,10-methyleneTHF polyglutamate + NADP+, Xenopus tropicalis"
Reactome:REACT_114836 "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+, Xenopus tropicalis"
Reactome:REACT_85239 "5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+, Sus scrofa"
Reactome:REACT_96601 "5,10-methenylTHF polyglutamate + NADPH + H+ <=> 5,10-methyleneTHF polyglutamate + NADP+, Sus scrofa"
GO:0004490 : methylglutaconyl-CoA hydratase activity
xref
Reactome:REACT_114406 "beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA, Mycobacterium tuberculosis"
GO:0004493 : methylmalonyl-CoA epimerase activity
synonym
"dl-methylmalonyl-CoA racemase activity" EXACT [EC:5.1.99.1]
GO:0004494 : methylmalonyl-CoA mutase activity
xref
Reactome:REACT_102288 "L-methylmalonyl-CoA <=> succinyl-CoA, Sus scrofa"
xref
Reactome:REACT_114493 "L-methylmalonyl-CoA <=> succinyl-CoA, Xenopus tropicalis"
Reactome:REACT_95870 "L-methylmalonyl-CoA <=> succinyl-CoA, Sus scrofa"
GO:0004497 : monooxygenase activity
xref
Reactome:REACT_102176 "CYP4F11 omega-hydroxylates 3-hydroxypalmitate, Canis familiaris"
Reactome:REACT_104843 "CYP4F11 omega-hydroxylates 3-hydroxypalmitate, Sus scrofa"
Reactome:REACT_105821 "CYP3A43 catalyzes the 6beta-hydroxylation of testosterone, Rattus norvegicus"
Reactome:REACT_77846 "CYP3A43 catalyzes the 6beta-hydroxylation of testosterone, Canis familiaris"
Reactome:REACT_81830 "CYP3A43 catalyzes the 6beta-hydroxylation of testosterone, Caenorhabditis elegans"
Reactome:REACT_84580 "CYP3A43 catalyzes the 6beta-hydroxylation of testosterone, Bos taurus"
Reactome:REACT_85402 "CYP2W1 can oxidize indole, Taeniopygia guttata"
Reactome:REACT_86737 "FMO2 S-oxidizes the antithyroid drug methimazole, Xenopus tropicalis"
Reactome:REACT_89003 "CYP4F11 omega-hydroxylates 3-hydroxypalmitate, Bos taurus"
xref
Reactome:REACT_113028 "CYP3A43 catalyzes the 6beta-hydroxylation of testosterone, Taeniopygia guttata"
Reactome:REACT_115238 "FMO2 S-oxidizes the antithyroid drug methimazole, Danio rerio"
GO:0004498 : calcidiol 1-monooxygenase activity
synonym
"1-hydroxylase-25-hydroxyvitamin D3" RELATED [EC:1.14.13.13]
xref
Reactome:REACT_30110 "Further hydroxylation of calcidiol in kidney to form calcitriol, Caenorhabditis elegans"
synonym
"1-hydroxylase-25-hydroxyvitamin D3 activity" RELATED [EC:1.14.13.13]
GO:0004499 : flavin-containing monooxygenase activity
xref
Reactome:REACT_90669 "FMO1 N-oxidizes the anti-cancer drug tamoxifen, Dictyostelium discoideum"
xref
Reactome:REACT_113438 "FMO3 N-oxidizes the tertiary amine trimethylamine, Taeniopygia guttata"
Reactome:REACT_114014 "FMO1 N-oxidizes the anti-cancer drug tamoxifen, Danio rerio"
Reactome:REACT_114556 "FMO3 N-oxidizes the tertiary amine trimethylamine, Danio rerio"
Reactome:REACT_84504 "FMO1 N-oxidizes the anti-cancer drug tamoxifen, Dictyostelium discoideum"
GO:0004506 : squalene monooxygenase activity
xref
Reactome:REACT_80174 "Squalene is oxidized to its epoxide, Dictyostelium discoideum"
xref
Reactome:REACT_32861 "Squalene is oxidized to its epoxide, Dictyostelium discoideum"
GO:0004507 : steroid 11-beta-monooxygenase activity
xref
Reactome:REACT_77534 "11-deoxycortisol is oxidised to cortisol by CYP11B1, Caenorhabditis elegans"
Reactome:REACT_80041 "Hydroxylation of 11-deoxycorticosterone to form corticosterone, Caenorhabditis elegans"
GO:0004508 : steroid 17-alpha-monooxygenase activity
xref
Reactome:REACT_86382 "Hydroxylation of pregnenolone to form 17alpha-hydroxypregnenolone, Sus scrofa"
xref
Reactome:REACT_112434 "Side chain cleavage of 17alpha-hydroxyprogesterone to form 4-Androstene-3, 17-dione, Gallus gallus"
Reactome:REACT_113135 "Side chain cleavage of 17alpha-hydroxypregnenolone to yield DHA, Gallus gallus"
Reactome:REACT_113443 "Hydroxylation of progesterone to form 17alpha-hydroxyprogesterone, Gallus gallus"
Reactome:REACT_114963 "Hydroxylation of pregnenolone to form 17alpha-hydroxypregnenolone, Gallus gallus"
Reactome:REACT_85525 "Hydroxylation of pregnenolone to form 17alpha-hydroxypregnenolone, Sus scrofa"
GO:0004510 : tryptophan 5-monooxygenase activity
xref
Reactome:REACT_112261 "Tryptophan is hydroxylated, Dictyostelium discoideum"
GO:0004511 : tyrosine 3-monooxygenase activity
xref
Reactome:REACT_114697 "Tyrosine is hydroxylated to dopa, Dictyostelium discoideum"
GO:0004516 : nicotinate phosphoribosyltransferase activity
xref
Reactome:REACT_89648 "A phosphoribosyl group is added to nicotinate to form nicotinate mononucleotide (NaMN), Caenorhabditis elegans"
xref
Reactome:REACT_79471 "A phosphoribosyl group is added to nicotinate to form nicotinate mononucleotide (NaMN), Caenorhabditis elegans"
GO:0004517 : nitric-oxide synthase activity
xref
Reactome:REACT_30015 "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO), Staphylococcus aureus N315"
Reactome:REACT_30098 "Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO), Escherichia coli"
Reactome:REACT_83313 "NO biosynthesis, Dictyostelium discoideum"
Reactome:REACT_84069 "NO biosynthesis, Sus scrofa"
Reactome:REACT_86943 "NO biosynthesis, Drosophila melanogaster"
xref
Reactome:REACT_113518 "NO biosynthesis, Taeniopygia guttata"
Reactome:REACT_30996 "NO biosynthesis, Sus scrofa"
GO:0004519 : endonuclease activity
xref
Reactome:REACT_112366 "Removal of 3'-phosphoglycolate (PG) moiety from DSB ends, Danio rerio"
Reactome:REACT_112509 "Cleavage of mRNA at the 3'-end, Arabidopsis thaliana"
Reactome:REACT_112615 "Removal of 3'-phosphoglycolate (PG) moiety from DSB ends, Rattus norvegicus"
Reactome:REACT_112782 "Removal of 3'-phosphoglycolate (PG) moiety from DSB ends, Xenopus tropicalis"
Reactome:REACT_113127 "Removal of 3'-phosphoglycolate (PG) moiety from DSB ends, Taeniopygia guttata"
Reactome:REACT_113480 "Removal of 3'-phosphoglycolate (PG) moiety from DSB ends, Gallus gallus"
Reactome:REACT_113819 "Cleavage of mRNA at the 3'-end, Drosophila melanogaster"
Reactome:REACT_114931 "Removal of 3'-phosphoglycolate (PG) moiety from DSB ends, Canis familiaris"
Reactome:REACT_115221 "Removal of 3'-phosphoglycolate (PG) moiety from DSB ends, Mus musculus"
Reactome:REACT_115226 "Removal of 3'-phosphoglycolate (PG) moiety from DSB ends, Bos taurus"
Reactome:REACT_115382 "Removal of 3'-phosphoglycolate (PG) moiety from DSB ends, Sus scrofa"
GO:0004520 : endodeoxyribonuclease activity
xref
Reactome:REACT_102405 "APE1 mediated endonucleolytic cleavage at the 5' side of the base-free deoxyribose residue, Plasmodium falciparum"
Reactome:REACT_104308 "APE1 mediated endonucleolytic cleavage at the 5' side of the base-free deoxyribose residue, Oryza sativa"
Reactome:REACT_104620 "5' incision leading to excision of DNA fragment with lesion in TC-NER, Saccharomyces cerevisiae"
Reactome:REACT_109157 "3' incision of the lesioned strand of DNA in TC-NER, Saccharomyces cerevisiae"
Reactome:REACT_83782 "APE1 mediated endonucleolytic cleavage at the 5' side of the base-free deoxyribose residue, Arabidopsis thaliana"
Reactome:REACT_84229 "5' incision leading to excision of DNA fragment with lesion in TC-NER, Sus scrofa"
Reactome:REACT_91600 "5'-incision of DNA by ERCC1-XPF in GG-NER, Bos taurus"
xref
Reactome:REACT_112122 "5'-incision of DNA by ERCC1-XPF in GG-NER, Xenopus tropicalis"
Reactome:REACT_112152 "3' incision of the lesioned strand of DNA in TC-NER, Taeniopygia guttata"
Reactome:REACT_115154 "5' incision leading to excision of DNA fragment with lesion in TC-NER, Gallus gallus"
Reactome:REACT_115463 "5' incision leading to excision of DNA fragment with lesion in TC-NER, Taeniopygia guttata"
Reactome:REACT_115479 "3' incision of the lesioned strand of DNA in TC-NER, Gallus gallus"
Reactome:REACT_32833 "3' incision of the lesioned strand of DNA in TC-NER, Saccharomyces cerevisiae"
Reactome:REACT_78421 "5' incision leading to excision of DNA fragment with lesion in TC-NER, Sus scrofa"
Reactome:REACT_98405 "5' incision leading to excision of DNA fragment with lesion in TC-NER, Saccharomyces cerevisiae"
GO:0004525 : ribonuclease III activity
xref
Reactome:REACT_85876 "Microprocessor complex cleaves pri-miRNA to pre-miRNA, Caenorhabditis elegans"
xref
Reactome:REACT_115273 "Dicer cleaves pre-miRNA to yield mature miRNA, Caenorhabditis elegans"
Reactome:REACT_92676 "Microprocessor complex cleaves pri-miRNA to pre-miRNA, Caenorhabditis elegans"
GO:0004534 : 5'-3' exoribonuclease activity
xref
Reactome:REACT_87101 "5' to 3' Exoribonuclease Digestion of Decapped mRNA, Rattus norvegicus"
xref
Reactome:REACT_112693 "5' to 3' Exoribonuclease Digestion of Decapped mRNA, Plasmodium falciparum"
Reactome:REACT_112806 "5' to 3' Exoribonuclease Digestion of Decapped mRNA, Dictyostelium discoideum"
GO:0004535 : poly(A)-specific ribonuclease activity
xref
Reactome:REACT_111967 "Deadenylation of mRNA by PARN, Taeniopygia guttata"
Reactome:REACT_112457 "Partial Deadenylation of mRNA by the PAN2-PAN3 Complex, Drosophila melanogaster"
Reactome:REACT_114879 "Deadenylation of mRNA by the CCR4-NOT Complex, Taeniopygia guttata"
GO:0004551 : nucleotide diphosphatase activity
xref
Reactome:REACT_106646 "FAD can be hydrolyzed back to FMN, Caenorhabditis elegans"
Reactome:REACT_97226 "FAD can be hydrolyzed back to FMN, Schizosaccharomyces pombe"
xref
Reactome:REACT_105775 "FAD can be hydrolyzed back to FMN, Schizosaccharomyces pombe"
Reactome:REACT_114734 "FAD can be hydrolyzed back to FMN, Xenopus tropicalis"
GO:0004555 : alpha,alpha-trehalase activity
xref
Reactome:REACT_113083 "trehalose + H2O => 2 D-glucose, Escherichia coli"
GO:0004556 : alpha-amylase activity
def
Catalysis of the endohydrolysis of 1,4-alpha-D-glucosidic linkages in polysaccharides containing three or more 1,4-alpha-linked D-glucose units.
def
Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units.
GO:0004558 : alpha-glucosidase activity
def
Catalysis of the hydrolysis of terminal, non-reducing 1,4-linked alpha-D-glucose residues with release of alpha-D-glucose.
xref
Reactome:REACT_31062 "maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase), Xenopus tropicalis"
Reactome:REACT_32647 "maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase), Rattus norvegicus"
Reactome:REACT_84980 "maltose + H2O => 2 D-glucose (maltase-glucoamylase), Xenopus tropicalis"
Reactome:REACT_98945 "maltose + H2O => 2 D-glucose (maltase-glucoamylase), Rattus norvegicus"
def
Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.
xref
Reactome:REACT_112486 "maltose + H2O => 2 D-glucose (sucrase-isomaltase), Taeniopygia guttata"
Reactome:REACT_113312 "Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose, Taeniopygia guttata"
Reactome:REACT_114036 "maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase), Taeniopygia guttata"
GO:0004568 : chitinase activity
def
Catalysis of the hydrolysis of 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins.
def
Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins.
GO:0004571 : mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
def
Catalysis of the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2).
def
Catalysis of the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2).
GO:0004572 : mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity
def
Catalysis of the hydrolysis of the terminal 1,3- and 1,6-linked alpha-D-mannose residues in the mannosyl-oligosaccharide Man(5)(GlcNAc)(3).
synonym
"alpha1-3,6-mannosidase activity" EXACT [EC:3.2.1.114]
def
Catalysis of the hydrolysis of the terminal (1->3)- and (1->6)-linked alpha-D-mannose residues in the mannosyl-oligosaccharide Man(5)(GlcNAc)(3).
synonym
"alpha-(1,3/6)-mannosidase activity" EXACT [EC:3.2.1.114]
"mannosyl-oligosaccharide (1->3)-(1->6)-alpha-mannosidase activity" EXACT []
"mannosyl-oligosaccharide (1->3,6)-alpha-mannosidase activity" EXACT []
"mannosyl-oligosaccharide (1->3/6)-alpha-mannosidase activity" EXACT []
GO:0004574 : oligo-1,6-glucosidase activity
def
Catalysis of the hydrolysis of 1,6-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose.
def
Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose.
GO:0004575 : sucrose alpha-glucosidase activity
xref
Reactome:REACT_113531 "sucrose + H2O => glucose + fructose, Taeniopygia guttata"
GO:0004582 : dolichyl-phosphate beta-D-mannosyltransferase activity
xref
Reactome:REACT_30274 "dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose, Dictyostelium discoideum"
Reactome:REACT_95320 "dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose, Sus scrofa"
xref
Reactome:REACT_92201 "dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose, Sus scrofa"
Reactome:REACT_95377 "dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose, Dictyostelium discoideum"
GO:0004584 : dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity
synonym
"oligomannosylsynthase activity" EXACT [EC:2.4.1.130]
synonym
"oligomannosylsynthase activity" BROAD [EC:2.4.1.130]
GO:0004586 : ornithine decarboxylase activity
xref
Reactome:REACT_112162 "ornithine => putrescine + CO2, Staphylococcus aureus N315"
Reactome:REACT_112888 "ornithine => putrescine + CO2, Drosophila melanogaster"
GO:0004587 : ornithine-oxo-acid transaminase activity
xref
Reactome:REACT_101723 "ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT], Dictyostelium discoideum"
xref
Reactome:REACT_104089 "ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT], Dictyostelium discoideum"
Reactome:REACT_112121 "glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT], Staphylococcus aureus N315"
Reactome:REACT_113272 "ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT], Staphylococcus aureus N315"
GO:0004594 : pantothenate kinase activity
xref
Reactome:REACT_96176 "Pantothenate is phosphorylated [PANK2], Bos taurus"
xref
Reactome:REACT_102890 "Pantothenate is phosphorylated [PANK2], Bos taurus"
Reactome:REACT_112157 "Pantothenate is phosphorylated [PANK1;3;4], Plasmodium falciparum"
Reactome:REACT_112376 "Pantothenate is phosphorylated [PANK2], Plasmodium falciparum"
Reactome:REACT_113306 "Pantothenate is phosphorylated [PANK1;3;4], Xenopus tropicalis"
GO:0004595 : pantetheine-phosphate adenylyltransferase activity
xref
Reactome:REACT_89354 "Adenylation of phosphopantetheine, Mycobacterium tuberculosis"
xref
Reactome:REACT_113938 "Adenylation of phosphopantetheine, Plasmodium falciparum"
GO:0004601 : peroxidase activity
xref
Reactome:REACT_107922 "Iodide is organified, Sus scrofa"
xref
Reactome:REACT_111983 "Tyrosine is monoiodinated, Dictyostelium discoideum"
Reactome:REACT_112213 "Iodide is organified, Danio rerio"
Reactome:REACT_112249 "Tyrosine is diiodinated, Dictyostelium discoideum"
Reactome:REACT_113235 "Tyrosine is diiodinated, Danio rerio"
Reactome:REACT_113904 "DIT and MIT combine to form triiodothyronine, Dictyostelium discoideum"
Reactome:REACT_113988 "Two DITs combine to form thyroxine, Dictyostelium discoideum"
Reactome:REACT_114100 "Iodide is organified, Dictyostelium discoideum"
Reactome:REACT_114351 "Tyrosine is monoiodinated, Danio rerio"
Reactome:REACT_114796 "DIT and MIT combine to form triiodothyronine, Danio rerio"
Reactome:REACT_115058 "Two DITs combine to form thyroxine, Danio rerio"
Reactome:REACT_97146 "Iodide is organified, Sus scrofa"
GO:0004602 : glutathione peroxidase activity
xref
Reactome:REACT_94600 "2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O, Xenopus tropicalis"
xref
Reactome:REACT_112920 "2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O, Danio rerio"
Reactome:REACT_113573 "2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O, Plasmodium falciparum"
Reactome:REACT_114008 "2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O, Escherichia coli"
GO:0004613 : phosphoenolpyruvate carboxykinase (GTP) activity
xref
Reactome:REACT_80888 "oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix], Gallus gallus"
Reactome:REACT_84871 "oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [cytosol], Dictyostelium discoideum"
Reactome:REACT_95393 "oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix], Bos taurus"
xref
Reactome:REACT_77918 "oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix], Bos taurus"
Reactome:REACT_93986 "oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [cytosol], Dictyostelium discoideum"
GO:0004614 : phosphoglucomutase activity
xref
Reactome:REACT_109722 "alpha-D-Glucose 6-phosphate <=> D-Glucose 1-phosphate, Schizosaccharomyces pombe"
Reactome:REACT_28185 "alpha-D-Glucose 6-phosphate <=> D-Glucose 1-phosphate, Saccharomyces cerevisiae"
Reactome:REACT_32221 "D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate, Staphylococcus aureus N315"
Reactome:REACT_33235 "D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate, Dictyostelium discoideum"
Reactome:REACT_34003 "D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate, Caenorhabditis elegans"
Reactome:REACT_78351 "D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate, Drosophila melanogaster"
Reactome:REACT_92124 "alpha-D-Glucose 6-phosphate <=> D-Glucose 1-phosphate, Staphylococcus aureus N315"
Reactome:REACT_93865 "alpha-D-Glucose 6-phosphate <=> D-Glucose 1-phosphate, Drosophila melanogaster"
Reactome:REACT_94306 "alpha-D-Glucose 6-phosphate <=> D-Glucose 1-phosphate, Caenorhabditis elegans"
xref
Reactome:REACT_107017 "alpha-D-Glucose 6-phosphate <=> D-Glucose 1-phosphate, Schizosaccharomyces pombe"
Reactome:REACT_78611 "D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate, Dictyostelium discoideum"
Reactome:REACT_85304 "alpha-D-Glucose 6-phosphate <=> D-Glucose 1-phosphate, Saccharomyces cerevisiae"
GO:0004618 : phosphoglycerate kinase activity
xref
Reactome:REACT_101746 "1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ADP, Plasmodium falciparum"
Reactome:REACT_34152 "1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ADP, Escherichia coli"
Reactome:REACT_80945 "ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate, Caenorhabditis elegans"
Reactome:REACT_88265 "ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate, Escherichia coli"
Reactome:REACT_93972 "1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ADP, Caenorhabditis elegans"
xref
Reactome:REACT_113751 "ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate, Dictyostelium discoideum"
Reactome:REACT_114935 "1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ADP, Dictyostelium discoideum"
Reactome:REACT_97790 "1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ADP, Plasmodium falciparum"
GO:0004619 : phosphoglycerate mutase activity
xref
Reactome:REACT_110401 "2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate, Taeniopygia guttata"
Reactome:REACT_110510 "3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate, Taeniopygia guttata"
xref
Reactome:REACT_111991 "2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate, Plasmodium falciparum"
Reactome:REACT_112712 "3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate, Plasmodium falciparum"
Reactome:REACT_112969 "2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate, Escherichia coli"
Reactome:REACT_114968 "3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate, Dictyostelium discoideum"
Reactome:REACT_115206 "2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate, Dictyostelium discoideum"
Reactome:REACT_115355 "3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate, Escherichia coli"
GO:0004629 : phospholipase C activity
xref
Reactome:REACT_112092 "PLC gamma 2-mediated PIP2 hydrolysis, Caenorhabditis elegans"
Reactome:REACT_112217 "PLC beta-mediated PIP2 hydrolysis, Schizosaccharomyces pombe"
Reactome:REACT_112221 "Hydrolysis of 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate by Activated Phospholipase C Beta-1, Saccharomyces cerevisiae"
Reactome:REACT_112517 "PLC beta-mediated PIP2 hydrolysis, Saccharomyces cerevisiae"
Reactome:REACT_112637 "PLC gamma 2-mediated PIP2 hydrolysis, Drosophila melanogaster"
Reactome:REACT_112759 "PLC beta-mediated PIP2 hydrolysis, Dictyostelium discoideum"
Reactome:REACT_112950 "PLC gamma 2-mediated PIP2 hydrolysis, Arabidopsis thaliana"
Reactome:REACT_113114 "Hydrolysis of 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate by Activated Phospholipase C Beta-1, Dictyostelium discoideum"
Reactome:REACT_113364 "PLC gamma 2-mediated PIP2 hydrolysis, Dictyostelium discoideum"
Reactome:REACT_113464 "PLC gamma 2-mediated PIP2 hydrolysis, Plasmodium falciparum"
Reactome:REACT_113587 "PLC gamma 2-mediated PIP2 hydrolysis, Saccharomyces cerevisiae"
Reactome:REACT_114558 "Hydrolysis of 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate by Activated Phospholipase C Beta-1, Danio rerio"
Reactome:REACT_114743 "PLC gamma 2-mediated PIP2 hydrolysis, Oryza sativa"
Reactome:REACT_115019 "Hydrolysis of 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate by Activated Phospholipase C Beta-1, Schizosaccharomyces pombe"
Reactome:REACT_115219 "PLC gamma 2-mediated PIP2 hydrolysis, Schizosaccharomyces pombe"
GO:0004632 : phosphopantothenate--cysteine ligase activity
xref
Reactome:REACT_87274 "Condensation of phosphopantothenate with cysteine, Dictyostelium discoideum"
xref
Reactome:REACT_108690 "Condensation of phosphopantothenate with cysteine, Dictyostelium discoideum"
Reactome:REACT_112895 "Condensation of phosphopantothenate with cysteine, Oryza sativa"
Reactome:REACT_113780 "Condensation of phosphopantothenate with cysteine, Arabidopsis thaliana"
GO:0004634 : phosphopyruvate hydratase activity
xref
Reactome:REACT_112068 "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate, Mycobacterium tuberculosis"
Reactome:REACT_112478 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O, Saccharomyces cerevisiae"
Reactome:REACT_112581 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O, Schizosaccharomyces pombe"
Reactome:REACT_112691 "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate, Saccharomyces cerevisiae"
Reactome:REACT_112925 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O, Mycobacterium tuberculosis"
Reactome:REACT_112986 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O, Escherichia coli"
Reactome:REACT_113494 "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate, Dictyostelium discoideum"
Reactome:REACT_113501 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O, Oryza sativa"
Reactome:REACT_113666 "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate, Escherichia coli"
Reactome:REACT_113784 "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate, Arabidopsis thaliana"
Reactome:REACT_113920 "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate, Oryza sativa"
Reactome:REACT_114214 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O, Plasmodium falciparum"
Reactome:REACT_114276 "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate, Schizosaccharomyces pombe"
Reactome:REACT_114578 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O, Staphylococcus aureus N315"
Reactome:REACT_115184 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O, Dictyostelium discoideum"
Reactome:REACT_115250 "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate, Staphylococcus aureus N315"
Reactome:REACT_115259 "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O, Arabidopsis thaliana"
Reactome:REACT_115437 "Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate, Plasmodium falciparum"
GO:0004637 : phosphoribosylamine-glycine ligase activity
xref
Reactome:REACT_28515 "5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi, Caenorhabditis elegans"
xref
Reactome:REACT_93559 "5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi, Caenorhabditis elegans"
GO:0004638 : phosphoribosylaminoimidazole carboxylase activity
xref
Reactome:REACT_97249 "AIR + CO2 => CAIR, Dictyostelium discoideum"
GO:0004639 : phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
xref
Reactome:REACT_89602 "CAIR + Aspartate + ATP => SAICAR + ADP + Pi, Dictyostelium discoideum"
GO:0004642 : phosphoribosylformylglycinamidine synthase activity
xref
Reactome:REACT_108004 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Mycobacterium tuberculosis"
Reactome:REACT_110291 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Saccharomyces cerevisiae"
Reactome:REACT_32434 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Staphylococcus aureus N315"
Reactome:REACT_34081 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Caenorhabditis elegans"
Reactome:REACT_83796 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Oryza sativa"
xref
Reactome:REACT_108774 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Saccharomyces cerevisiae"
Reactome:REACT_112941 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Xenopus tropicalis"
Reactome:REACT_80793 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Caenorhabditis elegans"
GO:0004643 : phosphoribosylaminoimidazolecarboxamide formyltransferase activity
xref
Reactome:REACT_108923 "AICAR + 10-Formyl-THF => FAICAR + THF, Dictyostelium discoideum"
Reactome:REACT_83713 "AICAR + 10-Formyl-THF => FAICAR + THF, Caenorhabditis elegans"
xref
Reactome:REACT_96335 "AICAR + 10-Formyl-THF => FAICAR + THF, Caenorhabditis elegans"
Reactome:REACT_98007 "AICAR + 10-Formyl-THF => FAICAR + THF, Dictyostelium discoideum"
GO:0004650 : polygalacturonase activity
def
Catalysis of the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans.
def
Catalysis of the random hydrolysis of (1->4)-alpha-D-galactosiduronic linkages in pectate and other galacturonans.
GO:0004652 : polynucleotide adenylyltransferase activity
xref
Reactome:REACT_101636 "mRNA polyadenylation, Rattus norvegicus"
xref
Reactome:REACT_111985 "mRNA polyadenylation, Arabidopsis thaliana"
Reactome:REACT_112181 "mRNA polyadenylation, Caenorhabditis elegans"
Reactome:REACT_113637 "mRNA polyadenylation, Oryza sativa"
Reactome:REACT_113649 "mRNA polyadenylation, Drosophila melanogaster"
GO:0004657 : proline dehydrogenase activity
xref
Reactome:REACT_102643 "proline => L-1-pyrroline-5-carboxylate, Saccharomyces cerevisiae"
Reactome:REACT_103115 "proline => L-1-pyrroline-5-carboxylate, Schizosaccharomyces pombe"
GO:0004666 : prostaglandin-endoperoxide synthase activity
xref
Reactome:REACT_101630 "Arachidonic acid oxidised to PGG2, Sus scrofa"
Reactome:REACT_101694 "Arachidonic acid oxidised to PGG2, Bos taurus"
xref
Reactome:REACT_30504 "Arachidonic acid oxidised to PGG2, Sus scrofa"
Reactome:REACT_85880 "Arachidonic acid oxidised to PGG2, Bos taurus"
GO:0004672 : protein kinase activity
xref
Reactome:REACT_6862 "Multiple IRAK1 autophosphorylation steps, Chlamydia trachomatis"
Reactome:REACT_80082 "Phosphorylation and release of IRF3/IRF7, Sus scrofa"
Reactome:REACT_85508 "LKB1 phosphorylates the alpha subunit of AMPK heterotrimer, Saccharomyces cerevisiae"
xref
Reactome:REACT_111075 "Phosphorylation of LIN52 component of MuvB by DYRK1A, Homo sapiens"
Reactome:REACT_111995 "Phosphorylation of p130Cas by SRC-FADK1 complex, Drosophila melanogaster"
Reactome:REACT_112267 "Autophosphorylation of FADK1 at Y397, Drosophila melanogaster"
Reactome:REACT_112918 "Phosphorylation and activation of Ezrin, Caenorhabditis elegans"
Reactome:REACT_113100 "Activated Src activates ERK, Drosophila melanogaster"
Reactome:REACT_113334 "PKC phosphorylates GRK2, Caenorhabditis elegans"
Reactome:REACT_113440 "Phosphorylation and release of IRF3/IRF7, Xenopus tropicalis"
Reactome:REACT_113589 "Phosphorylation of pFADK1 by SRC, Drosophila melanogaster"
Reactome:REACT_113821 "Activated Src activates ERK, Caenorhabditis elegans"
Reactome:REACT_114093 "LKB1 phosphorylates the alpha subunit of AMPK heterotrimer, Danio rerio"
Reactome:REACT_114693 "Phosphorylation of pFADK1 by SRC, Xenopus tropicalis"
Reactome:REACT_6862 "Multiple IRAK1 autophosphorylation steps, Homo sapiens"
Reactome:REACT_88178 "Phosphorylation and release of IRF3/IRF7, Sus scrofa"
GO:0004674 : protein serine/threonine kinase activity
synonym
"glycogen synthase a kinase activity" NARROW [EC:2.7.11.1]
xref
Reactome:REACT_100705 "AKT phosphorylates CREB, Drosophila melanogaster"
Reactome:REACT_100983 "PKA phosphorylates CREB, Drosophila melanogaster"
Reactome:REACT_101144 "TORC2 (mTOR) phosphorylates AKT at S473, Dictyostelium discoideum"
Reactome:REACT_102500 "AKT can phosphorylate SRK, Rattus norvegicus"
Reactome:REACT_102840 "MAPKAPK2 phosphorylates CREB at Serine 133, Drosophila melanogaster"
Reactome:REACT_104657 "MSK1 activates ATF1, Drosophila melanogaster"
Reactome:REACT_105863 "Phosphorylation of LIMK-1 by PAK, Bos taurus"
Reactome:REACT_106970 "AKT phosphorylates GSK3, Dictyostelium discoideum"
Reactome:REACT_108115 "Phosphorylation of cofilin by LIMK-1, Bos taurus"
Reactome:REACT_108360 "AKT phosphorylates GSK3, Caenorhabditis elegans"
Reactome:REACT_108483 "MAP kinase activates MAPKAPK2, MAPKAPK3 and MSK1, Saccharomyces cerevisiae"
Reactome:REACT_110094 "AKT can phosphorylate SRK, Taeniopygia guttata"
Reactome:REACT_110258 "Active p38 MAPK phosphorylates MAPKAPK2 or 3, Saccharomyces cerevisiae"
Reactome:REACT_110482 "AKT can phosphorylate SRK, Dictyostelium discoideum"
Reactome:REACT_12485 "AKT can phosphorylate SRK, Homo sapiens"
Reactome:REACT_25097 "IRAK4 autophosphorylation in the complex with activated TLR:MyD88:Mal, Chlamydia trachomatis"
Reactome:REACT_28277 "PDK1 phosphorylates AKT at T308, Dictyostelium discoideum"
Reactome:REACT_28491 "Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9, Sus scrofa"
Reactome:REACT_29796 "Myosin regulatory light chain phosphorylation by ROCK, Sus scrofa"
Reactome:REACT_32495 "Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9, Sus scrofa"
Reactome:REACT_33772 "MSK1 activates CREB, Drosophila melanogaster"
Reactome:REACT_34316 "Phosphorylation of cofilin by LIMK-1, Rattus norvegicus"
Reactome:REACT_34471 "Transphosphorylation of pLIMK1, Drosophila melanogaster"
Reactome:REACT_34701 "AKT can phosphorylate SRK, Bos taurus"
Reactome:REACT_6728 "Phosphorylation of IRF-3/IRF7 and their release from the activated TLR4 complex, Chlamydia trachomatis"
Reactome:REACT_6794 "Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal, Chlamydia trachomatis"
Reactome:REACT_6833 "First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal, Chlamydia trachomatis"
Reactome:REACT_6973 "RIP1 facilitates IKK complex phosphorylation, Homo sapiens"
Reactome:REACT_81707 "First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9, Sus scrofa"
Reactome:REACT_82094 "AKT can phosphorylate SRK, Canis familiaris"
Reactome:REACT_82420 "Active p38 MAPK phosphorylates MAPKAPK2 or 3, Schizosaccharomyces pombe"
Reactome:REACT_83130 "LIM kinase phosphorylation by ROCK, Bos taurus"
Reactome:REACT_83305 "Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9, Drosophila melanogaster"
Reactome:REACT_84316 "Phosphorylation of Cdc25C at Ser 216 by Chk1, Danio rerio"
Reactome:REACT_84544 "First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9, Drosophila melanogaster"
Reactome:REACT_85988 "Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9, Drosophila melanogaster"
Reactome:REACT_86248 "Myosin regulatory light chain phosphorylation by ROCK, Drosophila melanogaster"
Reactome:REACT_87109 "Autophosphorylation of IRE1 dimer, Caenorhabditis elegans"
Reactome:REACT_88834 "Inactivation of MEK1 by p34cdc2, Sus scrofa"
Reactome:REACT_91635 "MAP kinase activates MAPKAPK2, MAPKAPK3 and MSK1, Schizosaccharomyces pombe"
Reactome:REACT_92561 "Phosphorylation of PKC theta, Dictyostelium discoideum"
Reactome:REACT_92752 "IRAK is activated, Sus scrofa"
Reactome:REACT_93573 "AKT can phosphorylate SRK, Caenorhabditis elegans"
Reactome:REACT_93892 "hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP, Drosophila melanogaster"
Reactome:REACT_94439 "monophospho-CERT + 2 ATP => multiphospho-CERT + 2 ADP, Xenopus tropicalis"
Reactome:REACT_96427 "AKT can phosphorylate SRK, Drosophila melanogaster"
Reactome:REACT_96890 "RSK1/2/3 phosphorylates CREB at Serine 133, Drosophila melanogaster"
Reactome:REACT_96902 "MEK1 phosphorylates ERK-1, Saccharomyces cerevisiae"
Reactome:REACT_97853 "AKT can phosphorylate SRK, Mus musculus"
Reactome:REACT_97916 "Transphosphorylation of pLIMK1, Bos taurus"
Reactome:REACT_99441 "RSK1/2/3 phosphorylates CREB at Serine 133, Sus scrofa"
xref
Reactome:REACT_102053 "MEK1 phosphorylates ERK-1, Saccharomyces cerevisiae"
Reactome:REACT_102500 "AKT can phosphorylate RSK, Rattus norvegicus"
Reactome:REACT_110094 "AKT can phosphorylate RSK, Taeniopygia guttata"
Reactome:REACT_111058 "Phosphorylation of Smad2 by Nodal Receptor, Homo sapiens"
Reactome:REACT_111063 "SPRY2 is phosphorylated by phosphorylated MNK1, Homo sapiens"
Reactome:REACT_111068 "ACVR2A/B (ActRIIA/B) Phosphorylates ACVR1B (ActRIB, ALK4) in Response to Activin, Homo sapiens"
Reactome:REACT_111117 "p-MEK phosphorylates ERK, Homo sapiens"
Reactome:REACT_111130 "Type II Activin Receptor (ActRIIB/ACVR2B) Phosphorylates Type I Activin Receptor (ActRIC/ACVR1C) in Response to NODAL, Homo sapiens"
Reactome:REACT_111131 "Type II Activin Receptor (ActRII/ACVR2) Phosphorylates Type I Activin Receptor (ActRIB/ACVR1B) in Response to NODAL, Homo sapiens"
Reactome:REACT_111138 "Phosphorylation of R-SMAD2/3 by NODAL Receptor, Homo sapiens"
Reactome:REACT_111196 "PKC alpha interacts with and phosphorylates KIT, Homo sapiens"
Reactome:REACT_111939 "Activated TAK1 mediates phosphorylation of the IKK Complex, Xenopus tropicalis"
Reactome:REACT_111972 "Autophosphorylation of IRE1 dimer, Arabidopsis thaliana"
Reactome:REACT_112003 "Phosphorylation of PKC theta, Saccharomyces cerevisiae"
Reactome:REACT_112061 "Phosphorylation of Cdc25C at Ser 216 by Chk1, Schizosaccharomyces pombe"
Reactome:REACT_112107 "AKT phosphorylates caspase-9, Gallus gallus"
Reactome:REACT_112321 "Phosphorylation of L1 by p90rsk, Schizosaccharomyces pombe"
Reactome:REACT_112392 "AKT phosphorylates FOXO1A, Canis familiaris"
Reactome:REACT_112393 "AKT phosphorylates p21Cip1 and p27Kip1, Gallus gallus"
Reactome:REACT_112404 "Inactivation of MEK1 by p34cdc2, Saccharomyces cerevisiae"
Reactome:REACT_112488 "Inactivation of MEK1 by p34cdc2, Schizosaccharomyces pombe"
Reactome:REACT_112501 "Phosphorylation of L1 by p90rsk, Saccharomyces cerevisiae"
Reactome:REACT_112505 "TORC2 (mTOR) phosphorylates AKT at S473, Schizosaccharomyces pombe"
Reactome:REACT_112514 "Activation of IKK complex, Xenopus tropicalis"
Reactome:REACT_112516 "TORC2 (mTOR) phosphorylates AKT at S473, Saccharomyces cerevisiae"
Reactome:REACT_112550 "AKT phosphorylates GSK3, Schizosaccharomyces pombe"
Reactome:REACT_112561 "AKT phosphorylates FOXO1A, Bos taurus"
Reactome:REACT_112583 "AKT phosphorylates GSK3, Gallus gallus"
Reactome:REACT_112607 "AKT can phosphorylate RSK, Schizosaccharomyces pombe"
Reactome:REACT_112628 "AKT phosphorylates FOXO1A, Taeniopygia guttata"
Reactome:REACT_112928 "Autophosphorylation of IRE1 dimer, Xenopus tropicalis"
Reactome:REACT_112965 "AKT can phosphorylate RSK, Saccharomyces cerevisiae"
Reactome:REACT_113006 "ERK1/2 phosphorylates MSK1, Oryza sativa"
Reactome:REACT_113045 "AKT phosphorylates FOXO1A, Drosophila melanogaster"
Reactome:REACT_113059 "Autophosphorylation of IRE1 dimer, Dictyostelium discoideum"
Reactome:REACT_113062 "CERT + ATP => monophospho-CERT + ADP, Sus scrofa"
Reactome:REACT_113187 "ERK1/2 phosphorylates MSK1, Dictyostelium discoideum"
Reactome:REACT_113199 "Activation of NF-kB complex, Taeniopygia guttata"
Reactome:REACT_113389 "AKT phosphorylates FOXO1A, Mus musculus"
Reactome:REACT_113424 "PDK1 phosphorylates AKT at T308, Gallus gallus"
Reactome:REACT_113479 "ERK1/2 activates ELK1, Taeniopygia guttata"
Reactome:REACT_113486 "AKT phosphorylates TSC2, inhibiting it, Gallus gallus"
Reactome:REACT_113508 "AKT phosphorylates GSK3, Drosophila melanogaster"
Reactome:REACT_113549 "ERK1/2/5 activate RSK1/2/3, Oryza sativa"
Reactome:REACT_113560 "AKT interacts and phosphorylates Cot, Gallus gallus"
Reactome:REACT_113575 "MEK1 phosphorylates ERK-1, Arabidopsis thaliana"
Reactome:REACT_113600 "Phosphorylation of PKC theta, Schizosaccharomyces pombe"
Reactome:REACT_113619 "PDK1 phosphorylates AKT at T308, Saccharomyces cerevisiae"
Reactome:REACT_113634 "Activated TAK1 mediates phosphorylation of the IKK Complex, Drosophila melanogaster"
Reactome:REACT_113693 "MEK1 phosphorylates ERK-1, Oryza sativa"
Reactome:REACT_113717 "AKT can phosphorylate NUR77, Drosophila melanogaster"
Reactome:REACT_113719 "ERK1/2 phosphorylates MSK1, Schizosaccharomyces pombe"
Reactome:REACT_113729 "AKT phosphorylates TSC2, inhibiting it, Schizosaccharomyces pombe"
Reactome:REACT_113732 "p38MAPK phosphorylates MSK1, Arabidopsis thaliana"
Reactome:REACT_113744 "ERK1/2/5 activate RSK1/2/3, Schizosaccharomyces pombe"
Reactome:REACT_113764 "Phosphorylation of cofilin by LIMK-1, Danio rerio"
Reactome:REACT_113794 "Phospho-IKK Complex phosphorylates IkB within the IkB:NFkB Complex, Xenopus tropicalis"
Reactome:REACT_113810 "Phosphorylation of Bcl10, Xenopus tropicalis"
Reactome:REACT_113830 "MEK1 phosphorylates ERK-1, Dictyostelium discoideum"
Reactome:REACT_113835 "Transphosphorylation of pLIMK1, Taeniopygia guttata"
Reactome:REACT_113900 "CERT + ATP => monophospho-CERT + ADP, Caenorhabditis elegans"
Reactome:REACT_113949 "p38MAPK phosphorylates MSK1, Schizosaccharomyces pombe"
Reactome:REACT_114044 "Autophosphorylation of IRE1 dimer, Oryza sativa"
Reactome:REACT_114079 "PDK1 phosphorylates AKT at T308, Schizosaccharomyces pombe"
Reactome:REACT_114092 "AKT phosphorylates CREB, Gallus gallus"
Reactome:REACT_114136 "hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP, Caenorhabditis elegans"
Reactome:REACT_114306 "ERK1/2 phosphorylates MSK1, Arabidopsis thaliana"
Reactome:REACT_114321 "AKT phosphorylates IKKalpha, Gallus gallus"
Reactome:REACT_114322 "AKT phosphorylates FOXO1A, Rattus norvegicus"
Reactome:REACT_114335 "MSK1 activates CREB, Xenopus tropicalis"
Reactome:REACT_114476 "p38MAPK phosphorylates MSK1, Dictyostelium discoideum"
Reactome:REACT_114479 "AKT can phosphorylate NUR77, Caenorhabditis elegans"
Reactome:REACT_114548 "AKT phosphorylates MDM2, Gallus gallus"
Reactome:REACT_114581 "AKT can phosphorylate forkhead box transcription factors, Gallus gallus"
Reactome:REACT_114650 "ERK1/2 phosphorylates MSK1, Xenopus tropicalis"
Reactome:REACT_114660 "ERK1/2 activates ELK1, Xenopus tropicalis"
Reactome:REACT_114718 "ERK1/2 activates ELK1, Caenorhabditis elegans"
Reactome:REACT_114782 "ERK1/2/5 activate RSK1/2/3, Dictyostelium discoideum"
Reactome:REACT_114835 "AKT can phosphorylate forkhead box transcription factors, Drosophila melanogaster"
Reactome:REACT_114899 "MSK1 activates ATF1, Xenopus tropicalis"
Reactome:REACT_114971 "Phosphorylation of MARCKS by Protein kinase C, alpha type, Drosophila melanogaster"
Reactome:REACT_115073 "TORC2 (mTOR) phosphorylates AKT at S473, Gallus gallus"
Reactome:REACT_115253 "p38MAPK phosphorylates MSK1, Xenopus tropicalis"
Reactome:REACT_115290 "p38MAPK phosphorylates MSK1, Oryza sativa"
Reactome:REACT_115293 "Phosphorylation of Cdc25C at Ser 216 by Chk1, Saccharomyces cerevisiae"
Reactome:REACT_115340 "AKT phosphorylates FOXO1A, Gallus gallus"
Reactome:REACT_115364 "CERT + ATP => monophospho-CERT + ADP, Drosophila melanogaster"
Reactome:REACT_115391 "ERK1/2/5 activate RSK1/2/3, Arabidopsis thaliana"
Reactome:REACT_115462 "Phosphorylation of Cdc25C at Ser 216 by Chk1, Caenorhabditis elegans"
Reactome:REACT_115474 "AKT phosphorylates BAD, Xenopus tropicalis"
Reactome:REACT_12485 "AKT can phosphorylate RSK, Homo sapiens"
Reactome:REACT_25097 "IRAK4 autophosphorylation in the complex with activated TLR:MyD88:Mal, Homo sapiens"
Reactome:REACT_34104 "RSK1/2/3 phosphorylates CREB at Serine 133, Sus scrofa"
Reactome:REACT_34701 "AKT can phosphorylate RSK, Bos taurus"
Reactome:REACT_6728 "Phosphorylation of IRF-3/IRF7 and their release from the activated TLR4 complex, Homo sapiens"
Reactome:REACT_6794 "Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal, Homo sapiens"
Reactome:REACT_6833 "First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal, Homo sapiens"
Reactome:REACT_79081 "Autophosphorylation of IRE1 dimer, Caenorhabditis elegans"
Reactome:REACT_82094 "AKT can phosphorylate RSK, Canis familiaris"
Reactome:REACT_82465 "Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9, Sus scrofa"
Reactome:REACT_87625 "First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9, Sus scrofa"
Reactome:REACT_91830 "Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9, Sus scrofa"
Reactome:REACT_93998 "AKT can phosphorylate RSK, Caenorhabditis elegans"
Reactome:REACT_96427 "AKT can phosphorylate RSK, Drosophila melanogaster"
Reactome:REACT_96825 "IRAK is activated, Sus scrofa"
Reactome:REACT_97853 "AKT can phosphorylate RSK, Mus musculus"
GO:0004675 : transmembrane receptor protein serine/threonine kinase activity
xref
Reactome:REACT_106768 "Activated type I receptor phosphorylates R-SMAD directly, Canis familiaris"
Reactome:REACT_30655 "Activated type I receptor phosphorylates R-SMAD directly, Mus musculus"
Reactome:REACT_31200 "Activated type I receptor phosphorylates R-SMAD directly, Rattus norvegicus"
Reactome:REACT_31836 "Activated type I receptor phosphorylates R-SMAD directly, Danio rerio"
Reactome:REACT_31960 "Activated type I receptor phosphorylates R-SMAD directly, Xenopus tropicalis"
Reactome:REACT_6879 "Activated type I receptor phosphorylates R-SMAD directly, Homo sapiens"
Reactome:REACT_77790 "Activated type I receptor phosphorylates R-SMAD directly, Taeniopygia guttata"
Reactome:REACT_80118 "Activated type I receptor phosphorylates R-SMAD directly, Bos taurus"
Reactome:REACT_80791 "Activated type I receptor phosphorylates R-SMAD directly, Gallus gallus"
Reactome:REACT_81763 "Activated type I receptor phosphorylates R-SMAD directly, Sus scrofa"
xref
Reactome:REACT_106768 "Activated type I receptor phosphorylates SMAD2/3 directly, Canis familiaris"
Reactome:REACT_114102 "Activated type I receptor phosphorylates SMAD2/3 directly, Drosophila melanogaster"
Reactome:REACT_30655 "Activated type I receptor phosphorylates SMAD2/3 directly, Mus musculus"
Reactome:REACT_31200 "Activated type I receptor phosphorylates SMAD2/3 directly, Rattus norvegicus"
Reactome:REACT_31836 "Activated type I receptor phosphorylates SMAD2/3 directly, Danio rerio"
Reactome:REACT_31960 "Activated type I receptor phosphorylates SMAD2/3 directly, Xenopus tropicalis"
Reactome:REACT_6879 "Activated type I receptor phosphorylates SMAD2/3 directly, Homo sapiens"
Reactome:REACT_77790 "Activated type I receptor phosphorylates SMAD2/3 directly, Taeniopygia guttata"
Reactome:REACT_80118 "Activated type I receptor phosphorylates SMAD2/3 directly, Bos taurus"
Reactome:REACT_80791 "Activated type I receptor phosphorylates SMAD2/3 directly, Gallus gallus"
Reactome:REACT_81763 "Activated type I receptor phosphorylates SMAD2/3 directly, Sus scrofa"
GO:0004676 : 3-phosphoinositide-dependent protein kinase activity
xref
Reactome:REACT_104844 "PDK1 activates PKC zeta, Dictyostelium discoideum"
Reactome:REACT_29542 "PDK1 activates PKC zeta, Caenorhabditis elegans"
xref
Reactome:REACT_112574 "PDK1 activates PKC zeta, Schizosaccharomyces pombe"
Reactome:REACT_112723 "PDK1 activates PKC zeta, Gallus gallus"
Reactome:REACT_115114 "PDK1 activates PKC zeta, Saccharomyces cerevisiae"
GO:0004679 : AMP-activated protein kinase activity
xref
Reactome:REACT_101245 "Phosphorylation of ChREBP at Serine 568 by AMPK, Caenorhabditis elegans"
Reactome:REACT_79108 "pAMPK inactivates ACC2 inhibiting malonyl-CoA synthesis, Caenorhabditis elegans"
xref
Reactome:REACT_113551 "Phosphorylation of ChREBP at Serine 568 by AMPK, Danio rerio"
Reactome:REACT_114056 "pAMPK inactivates ACC2 inhibiting malonyl-CoA synthesis, Danio rerio"
Reactome:REACT_115260 "pAMPK inactivates ACC2 inhibiting malonyl-CoA synthesis, Taeniopygia guttata"
Reactome:REACT_115507 "Phosphorylation of ChREBP at Serine 568 by AMPK, Xenopus tropicalis"
GO:0004683 : calmodulin-dependent protein kinase activity
xref
Reactome:REACT_112694 "CaMK IV autophosphorylation, Xenopus tropicalis"
Reactome:REACT_113927 "CaMK IV phosphorylates CREB, Xenopus tropicalis"
Reactome:REACT_114360 "CaMK IV autophosphorylation, Dictyostelium discoideum"
GO:0004689 : phosphorylase kinase activity
synonym
"phosphorylase b kinase activity" EXACT [EC:2.7.11.19]
xref
Reactome:REACT_112850 "glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP, Danio rerio"
Reactome:REACT_113997 "glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP, Drosophila melanogaster"
Reactome:REACT_114606 "glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP, Xenopus tropicalis"
GO:0004691 : cAMP-dependent protein kinase activity
xref
Reactome:REACT_23999 "The common beta chain is phosphorylated on Ser-585, Homo sapiens"
Reactome:REACT_80893 "Phosphorylation of PF2K-Pase by PKA catalytic subunit, Saccharomyces cerevisiae"
Reactome:REACT_87995 "PKA phosphorylates PDE4B, Drosophila melanogaster"
Reactome:REACT_88070 "Phosphorylation of PF2K-Pase by PKA catalytic subunit, Schizosaccharomyces pombe"
Reactome:REACT_92457 "Phosphorylation of PF2K-Pase by PKA catalytic subunit, Drosophila melanogaster"
xref
Reactome:REACT_108468 "Phosphorylation of PF2K-Pase by PKA catalytic subunit, Schizosaccharomyces pombe"
Reactome:REACT_112372 "Phosphorylation of ChREBP at Thr(666) by PKA, Xenopus tropicalis"
Reactome:REACT_112409 "Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA), Xenopus tropicalis"
Reactome:REACT_112611 "Phosphorylation of pChREBP (Thr 666) at Ser(196) by PKA, Xenopus tropicalis"
Reactome:REACT_113680 "Phosphorylation of PF2K-Pase by PKA catalytic subunit, Gallus gallus"
Reactome:REACT_114719 "PKA phosphorylates DARPP-32 on Thr34, Xenopus tropicalis"
Reactome:REACT_114883 "PKA phosphorylates PDE4B, Plasmodium falciparum"
Reactome:REACT_115177 "PKA phosphorylates PDE4B, Caenorhabditis elegans"
Reactome:REACT_115301 "PKA phosphorylates PDE4B, Dictyostelium discoideum"
Reactome:REACT_23999 "IL3RB is phosphorylated on Ser-585, Homo sapiens"
Reactome:REACT_94203 "Phosphorylation of PF2K-Pase by PKA catalytic subunit, Saccharomyces cerevisiae"
GO:0004692 : cGMP-dependent protein kinase activity
xref
Reactome:REACT_111129 "Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II, Homo sapiens"
Reactome:REACT_111245 "PTPS is phosphorylated by cGMP-dependant protein kinase II, Homo sapiens"
Reactome:REACT_114536 "PKG1 phosphorylates IRAG:IP3R1 inhibiting IP3-stimulated Ca2+ release, Xenopus tropicalis"
GO:0004693 : cyclin-dependent protein kinase activity
xref
Reactome:REACT_104569 "Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160), Drosophila melanogaster"
Reactome:REACT_79948 "Phosphorylation of Cdh1 by Cyclin B1:Cdc2, Caenorhabditis elegans"
Reactome:REACT_82588 "Phosphorylation of M phase proteins by active Cyclin B1:Cdc2 complexes, Caenorhabditis elegans"
Reactome:REACT_85295 "Cyclin E:Cdk2-mediated phosphorylation of Rb, Sus scrofa"
xref
Reactome:REACT_111206 "Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex, Homo sapiens"
Reactome:REACT_111248 "Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex, Homo sapiens"
Reactome:REACT_112082 "Cyclin D:Cdk4/6 mediated phosphorylation of Rb and dissociation of phospho-Rb from the E2F1/2/3:DP-1 complexes, Xenopus tropicalis"
Reactome:REACT_112868 "Cyclin B/Cdk1 mediate phosphorylation of NuMA, Xenopus tropicalis"
Reactome:REACT_113042 "Phosphorylation of Cdh1 by Cyclin B1:Cdc2, Saccharomyces cerevisiae"
Reactome:REACT_113645 "Cyclin E:Cdk2-mediated phosphorylation of Rb, Xenopus tropicalis"
Reactome:REACT_113808 "Phosphorylation of Cdh1 by Cyclin B1:Cdc2, Schizosaccharomyces pombe"
Reactome:REACT_113866 "Phosphorylation of M phase proteins by active Cyclin B1:Cdc2 complexes, Schizosaccharomyces pombe"
Reactome:REACT_115193 "CDK5 phosphorylates DARPP-32 on Thr75, Xenopus tropicalis"
Reactome:REACT_115457 "Phosphorylation of M phase proteins by active Cyclin B1:Cdc2 complexes, Saccharomyces cerevisiae"
Reactome:REACT_91084 "Cyclin E:Cdk2-mediated phosphorylation of Rb, Sus scrofa"
GO:0004697 : protein kinase C activity
xref
Reactome:REACT_105020 "DAG stimulates protein kinase C-delta, Dictyostelium discoideum"
Reactome:REACT_91630 "DAG stimulates protein kinase C-delta, Sus scrofa"
xref
Reactome:REACT_113213 "DAG stimulates protein kinase C-delta, Saccharomyces cerevisiae"
Reactome:REACT_113684 "DAG stimulates protein kinase C-delta, Schizosaccharomyces pombe"
Reactome:REACT_28264 "DAG stimulates protein kinase C-delta, Sus scrofa"
GO:0004698 : calcium-dependent protein kinase C activity
xref
Reactome:REACT_32031 "Phosphorylation of Platelet Sec-1, Dictyostelium discoideum"
Reactome:REACT_91722 "Phosphorylation of Syntaxin-4, Dictyostelium discoideum"
xref
Reactome:REACT_111973 "Phosphorylation of Syntaxin-4, Saccharomyces cerevisiae"
Reactome:REACT_111980 "Phosphorylation of Syntaxin-4, Schizosaccharomyces pombe"
Reactome:REACT_112603 "Phosphorylation of Platelet Sec-1, Schizosaccharomyces pombe"
Reactome:REACT_112939 "Endocytosis of Ca impermeable AMPA receptors, Xenopus tropicalis"
Reactome:REACT_113338 "Phosphorylation of Platelet Sec-1, Saccharomyces cerevisiae"
Reactome:REACT_115137 "Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites, Xenopus tropicalis"
GO:0004705 : JUN kinase activity
xref
Reactome:REACT_113885 "JNK phosphorylates BIM, BAD and other targets, Xenopus tropicalis"
GO:0004707 : MAP kinase activity
xref
Reactome:REACT_83486 "Activation of p38MAPK by DSCAM, Drosophila melanogaster"
xref
Reactome:REACT_111161 "Activated ERK1/2 threonine-phosphorylate FRS2alpha., Homo sapiens"
Reactome:REACT_115393 "Phosphorylation of UBF-1:rDNA Promoter, Rattus norvegicus"
GO:0004709 : MAP kinase kinase kinase activity
xref
Reactome:REACT_114785 "Akt:pCot phosphorylates NIK, Gallus gallus"
GO:0004712 : protein serine/threonine/tyrosine kinase activity
xref
Reactome:REACT_106337 "activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3, Schizosaccharomyces pombe"
Reactome:REACT_95515 "activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3, Saccharomyces cerevisiae"
GO:0004713 : protein tyrosine kinase activity
xref
Reactome:REACT_105313 "Activation of Src, Bos taurus"
Reactome:REACT_106096 "SHC becomes phosphorylated, Gallus gallus"
Reactome:REACT_106379 "Phosphorylation of Cbl (EGFR:Cbl), Xenopus tropicalis"
Reactome:REACT_107024 "Activation of Vav1, Sus scrofa"
Reactome:REACT_107486 "Phosphorylation of ITAM motifs in CD3 complexes, Sus scrofa"
Reactome:REACT_108276 "SHC becomes phosphorylated, Mus musculus"
Reactome:REACT_109237 "Phosphorylation of Cbl (EGFR:Cbl:Grb2), Mus musculus"
Reactome:REACT_12424 "Phosphorylation of Cbl (EGFR:Cbl), Homo sapiens"
Reactome:REACT_12491 "Phosphorylation of Cbl (EGFR:Cbl:Grb2), Homo sapiens"
Reactome:REACT_21344 "SHC becomes phosphorylated, Homo sapiens"
Reactome:REACT_28594 "Autophosphorylation of PDGF alpha receptors, Drosophila melanogaster"
Reactome:REACT_29123 "Phosphorylation of Cbl (EGFR:Cbl:Grb2), Bos taurus"
Reactome:REACT_29482 "Activation of Lck, Sus scrofa"
Reactome:REACT_30339 "Autophosphorylation of PDGF beta receptors, Drosophila melanogaster"
Reactome:REACT_31634 "Phosphorylation of Cbl (EGFR:Cbl:Grb2), Danio rerio"
Reactome:REACT_32619 "Phosphorylation of TBSMs in LAT, Sus scrofa"
Reactome:REACT_33766 "SHC becomes phosphorylated, Taeniopygia guttata"
Reactome:REACT_34183 "Phosphorylation of DCC by Fyn, Taeniopygia guttata"
Reactome:REACT_34631 "Phosphorylation of Cbl (EGFR:Cbl), Mus musculus"
Reactome:REACT_77187 "Phosphorylation of Cbl (EGFR:Cbl:Grb2), Rattus norvegicus"
Reactome:REACT_78499 "Change of PKC theta conformation, Sus scrofa"
Reactome:REACT_79877 "Autophosphorylation of PDGF alpha/beta receptors, Drosophila melanogaster"
Reactome:REACT_81025 "SHC becomes phosphorylated, Rattus norvegicus"
Reactome:REACT_81472 "SHC becomes phosphorylated, Xenopus tropicalis"
Reactome:REACT_82597 "Phosphorylation of Cbl (EGFR:Cbl:Grb2), Xenopus tropicalis"
Reactome:REACT_83830 "SHC becomes phosphorylated, Danio rerio"
Reactome:REACT_84824 "Phosphorylation of Cbl (EGFR:Cbl:Grb2), Gallus gallus"
Reactome:REACT_84931 "Phosphorylation of nephrin by the Src family kinase Fyn, Bos taurus"
Reactome:REACT_85443 "Phosphorylation of Cbl (EGFR:Cbl:Grb2), Taeniopygia guttata"
Reactome:REACT_86510 "Phosphorylation of Cbl (EGFR:Cbl), Canis familiaris"
Reactome:REACT_87034 "SHC becomes phosphorylated, Canis familiaris"
Reactome:REACT_87633 "Phosphorylation of L1 by EPHB2, Drosophila melanogaster"
Reactome:REACT_88507 "Phosphorylation of ZAP-70 by Lck, Sus scrofa"
Reactome:REACT_88609 "Phosphorylation of SLP-76, Sus scrofa"
Reactome:REACT_89762 "Phosphorylation of Cbl (EGFR:Cbl:Grb2), Canis familiaris"
Reactome:REACT_90342 "Phosphorylation of Cbl (EGFR:Cbl), Taeniopygia guttata"
Reactome:REACT_90842 "Phosphorylation of L1 by EPHB2, Caenorhabditis elegans"
Reactome:REACT_91362 "Inactivation of Lck by Csk, Sus scrofa"
Reactome:REACT_93370 "Recruitment of FAK to NCAM1:Fyn in lipid rafts, Caenorhabditis elegans"
Reactome:REACT_94045 "SHC becomes phosphorylated, Sus scrofa"
Reactome:REACT_94150 "Phosphorylation of Unc5C, Taeniopygia guttata"
Reactome:REACT_94384 "Phosphorylation of Cbl (EGFR:Cbl), Danio rerio"
Reactome:REACT_95250 "Activation of ZAP-70, Sus scrofa"
Reactome:REACT_97562 "Phosphorylation of Cbl (EGFR:Cbl), Rattus norvegicus"
Reactome:REACT_97992 "SEMA4D interacts with Plexin-B1:ErbB2, Bos taurus"
Reactome:REACT_99315 "SHC becomes phosphorylated, Bos taurus"
xref
Reactome:REACT_100038 "Phosphorylation of nephrin by the Src family kinase Fyn, Bos taurus"
Reactome:REACT_106379 "Phosphorylation of CBL (EGFR:CBL), Xenopus tropicalis"
Reactome:REACT_109237 "Phosphorylation of CBL (EGFR:GRB2:CBL), Mus musculus"
Reactome:REACT_111070 "Phosphorylation of JAK2, Homo sapiens"
Reactome:REACT_111072 "Phosphorylation and activation of VAV1, Homo sapiens"
Reactome:REACT_111096 "SRC phosphorylates SPRY2 on Y55 and Y227, Homo sapiens"
Reactome:REACT_111103 "Autophosphorylation of KIT, Homo sapiens"
Reactome:REACT_111110 "SHC1 is phosphorylated, Homo sapiens"
Reactome:REACT_111112 "Phosphorylation of APS, Homo sapiens"
Reactome:REACT_111134 "Phosphorylation of PLCgamma by PDGFR, Homo sapiens"
Reactome:REACT_111147 "JAK2 phosphorylation of GHR, Homo sapiens"
Reactome:REACT_111152 "Phosphorylation of SHP2 by SFKs, Homo sapiens"
Reactome:REACT_111186 "Phosphorylation of GAB2 by SFKs, Homo sapiens"
Reactome:REACT_111201 "Phosphorylation of FRS2-beta by activated FGFR, Homo sapiens"
Reactome:REACT_111218 "STAT5 tyrosine phosphorylation, Homo sapiens"
Reactome:REACT_111244 "Phosphorylation of STATs, Homo sapiens"
Reactome:REACT_111246 "Autocatalytic phosphorylation of BetaKlotho-bound FGFR4, Homo sapiens"
Reactome:REACT_111958 "Phosphorylation of APS, Rattus norvegicus"
Reactome:REACT_112027 "Autophosphorylation of KIT, Xenopus tropicalis"
Reactome:REACT_112044 "Autocatalytic phosphorylation of FGFR2b, Caenorhabditis elegans"
Reactome:REACT_112047 "Phosphorylation of Unc5C, Gallus gallus"
Reactome:REACT_112071 "Phosphorylation and activation of VAV1, Canis familiaris"
Reactome:REACT_112170 "Binding and activation of MAP Kinase, Oryza sativa"
Reactome:REACT_112193 "Autophosphorylation of KIT, Rattus norvegicus"
Reactome:REACT_112269 "Phosphorylation of L1 by SRC, Drosophila melanogaster"
Reactome:REACT_112299 "PLC gamma phosphorylation by FGFR, Drosophila melanogaster"
Reactome:REACT_112349 "SYK activation by SRC, Drosophila melanogaster"
Reactome:REACT_112362 "Phosphorylation of FADK1, Xenopus tropicalis"
Reactome:REACT_112411 "PLC gamma phosphorylation by FGFR, Caenorhabditis elegans"
Reactome:REACT_112557 "Autocatalytic phosphorylation of FGFR4, Caenorhabditis elegans"
Reactome:REACT_112582 "Phosphorylation of FRS2-beta by activated FGFR, Drosophila melanogaster"
Reactome:REACT_112962 "Phosphorylation of APS, Bos taurus"
Reactome:REACT_112967 "Phosphorylation of APS, Canis familiaris"
Reactome:REACT_113016 "Phosphorylation of FRS2-beta by activated FGFR, Gallus gallus"
Reactome:REACT_113054 "Autocatalytic phosphorylation of FGFR3c, Caenorhabditis elegans"
Reactome:REACT_113122 "Autocatalytic phosphorylation of FGFR1c, Caenorhabditis elegans"
Reactome:REACT_113138 "Phosphorylation of FRS2-beta by activated FGFR, Caenorhabditis elegans"
Reactome:REACT_113262 "Phosphorylation of APS, Xenopus tropicalis"
Reactome:REACT_113307 "Phosphorylation and activation of VAV1, Bos taurus"
Reactome:REACT_113363 "Phosphorylation of nephrin by the Src family kinase Fyn, Xenopus tropicalis"
Reactome:REACT_113366 "Phosphorylation of nephrin by the Src family kinase Fyn, Caenorhabditis elegans"
Reactome:REACT_113372 "Phosphorylation of L1 by SRC, Caenorhabditis elegans"
Reactome:REACT_113384 "Autophosphorylation of SRC, Xenopus tropicalis"
Reactome:REACT_113409 "Autophosphorylation of KIT, Canis familiaris"
Reactome:REACT_113474 "Autophosphorylation of KIT, Gallus gallus"
Reactome:REACT_113502 "Phosphorylation of FAK by Src kinase, Drosophila melanogaster"
Reactome:REACT_113605 "Phosphorylation and activation of VAV1, Mus musculus"
Reactome:REACT_113630 "Phosphorylation and activation of VAV1, Xenopus tropicalis"
Reactome:REACT_113647 "Autophosphorylation of KIT, Taeniopygia guttata"
Reactome:REACT_113655 "Autophosphorylation of KIT, Mus musculus"
Reactome:REACT_113678 "SHP2 is phosphorylated by activated FGFR, Caenorhabditis elegans"
Reactome:REACT_113688 "Phosphorylation of ITIM in SIRP alpha, Sus scrofa"
Reactome:REACT_113709 "Phosphorylation of CD28, Xenopus tropicalis"
Reactome:REACT_113738 "Autophosphorylation of KIT, Sus scrofa"
Reactome:REACT_113759 "Phosphorylation of ITIM in SIRP alpha, Taeniopygia guttata"
Reactome:REACT_113828 "Autophosphorylation of PDGF beta receptors, Xenopus tropicalis"
Reactome:REACT_113861 "Phosphorylation of APS, Gallus gallus"
Reactome:REACT_113884 "Phosphorylation of APS, Sus scrofa"
Reactome:REACT_113926 "Phosphorylation of APS, Mus musculus"
Reactome:REACT_114012 "Phosphorylation of FRS2-beta by activated FGFR, Canis familiaris"
Reactome:REACT_114045 "Autocatalytic phosphorylation of FGFR1b, Caenorhabditis elegans"
Reactome:REACT_114111 "Phosphorylation of Unc5C, Drosophila melanogaster"
Reactome:REACT_114124 "Phosphorylation of PLC-gamma1, Xenopus tropicalis"
Reactome:REACT_114129 "Phosphorylation of FRS2-alpha by activated FGFR, Caenorhabditis elegans"
Reactome:REACT_114167 "Phosphorylation of APS, Danio rerio"
Reactome:REACT_114185 "Phosphorylation of nephrin by the Src family kinase Fyn, Drosophila melanogaster"
Reactome:REACT_114530 "Phosphorylation of FRS2-beta by activated FGFR, Xenopus tropicalis"
Reactome:REACT_114569 "Phosphorylation of ITIM in SIRP alpha, Bos taurus"
Reactome:REACT_114600 "Binding and activation of MAP Kinase, Dictyostelium discoideum"
Reactome:REACT_114640 "Phosphorylation of APS, Taeniopygia guttata"
Reactome:REACT_114674 "Autophosphorylation of KIT, Bos taurus"
Reactome:REACT_114702 "Autocatalytic phosphorylation of FGFR3b, Caenorhabditis elegans"
Reactome:REACT_114781 "Binding and activation of MAP Kinase, Arabidopsis thaliana"
Reactome:REACT_114786 "Autophosphorylation of KIT, Danio rerio"
Reactome:REACT_114856 "Phosphorylation of FRS2-beta by activated FGFR, Danio rerio"
Reactome:REACT_114870 "Phosphorylation of FRS2-beta by activated FGFR, Rattus norvegicus"
Reactome:REACT_114895 "Activation of SRC by Ral-GTP, Drosophila melanogaster"
Reactome:REACT_114914 "Phosphorylation of FRS2-beta by activated FGFR, Mus musculus"
Reactome:REACT_114996 "Autophosphorylation of NCAM1 bound Fyn, Drosophila melanogaster"
Reactome:REACT_114997 "Phosphorylation and activation of VAV1, Sus scrofa"
Reactome:REACT_115017 "Phosphorylation of FRS2-beta by activated FGFR, Taeniopygia guttata"
Reactome:REACT_115067 "Autocatalytic phosphorylation of FGFR2c, Caenorhabditis elegans"
Reactome:REACT_115068 "Phosphorylation of ITIM in SIRP alpha, Gallus gallus"
Reactome:REACT_115305 "Phosphorylation of DCC by Fyn, Gallus gallus"
Reactome:REACT_115354 "Phosphorylation of FRS2-beta by activated FGFR, Bos taurus"
Reactome:REACT_115375 "Autocatalytic phosphorylation of FGFR1b, Drosophila melanogaster"
Reactome:REACT_115402 "Phosphorylation of FRS2-beta by activated FGFR, Sus scrofa"
Reactome:REACT_115418 "Autocatalytic phosphorylation of FGFR2b, Drosophila melanogaster"
Reactome:REACT_115469 "Autophosphorylation of SRC, Drosophila melanogaster"
Reactome:REACT_115514 "Phosphorylation of Unc5C, Caenorhabditis elegans"
Reactome:REACT_12424 "Phosphorylation of CBL (EGFR:CBL), Homo sapiens"
Reactome:REACT_12491 "Phosphorylation of CBL (EGFR:GRB2:CBL), Homo sapiens"
Reactome:REACT_29123 "Phosphorylation of CBL (EGFR:GRB2:CBL), Bos taurus"
Reactome:REACT_31634 "Phosphorylation of CBL (EGFR:GRB2:CBL), Danio rerio"
Reactome:REACT_33942 "Activation of Src, Bos taurus"
Reactome:REACT_34631 "Phosphorylation of CBL (EGFR:CBL), Mus musculus"
Reactome:REACT_77187 "Phosphorylation of CBL (EGFR:GRB2:CBL), Rattus norvegicus"
Reactome:REACT_80684 "Activation of Vav1, Sus scrofa"
Reactome:REACT_82597 "Phosphorylation of CBL (EGFR:GRB2:CBL), Xenopus tropicalis"
Reactome:REACT_83486 "Binding and activation of MAP Kinase, Drosophila melanogaster"
Reactome:REACT_84824 "Phosphorylation of CBL (EGFR:GRB2:CBL), Gallus gallus"
Reactome:REACT_85443 "Phosphorylation of CBL (EGFR:GRB2:CBL), Taeniopygia guttata"
Reactome:REACT_86510 "Phosphorylation of CBL (EGFR:CBL), Canis familiaris"
Reactome:REACT_89762 "Phosphorylation of CBL (EGFR:GRB2:CBL), Canis familiaris"
Reactome:REACT_90301 "SEMA4D interacts with Plexin-B1:ErbB2, Bos taurus"
Reactome:REACT_94384 "Phosphorylation of CBL (EGFR:CBL), Danio rerio"
Reactome:REACT_97562 "Phosphorylation of CBL (EGFR:CBL), Rattus norvegicus"
GO:0004714 : transmembrane receptor protein tyrosine kinase activity
xref
Reactome:REACT_100726 "ARMS is phosphorylated by active TrkA receptor, Sus scrofa"
Reactome:REACT_104778 "Shc phosphorylation by phospho-EGFR:EGF, Taeniopygia guttata"
Reactome:REACT_107918 "Shc phosphorylation by phospho-EGFR:EGF, Gallus gallus"
Reactome:REACT_12592 "Shc phosphorylation by phospho-EGFR:EGF, Homo sapiens"
Reactome:REACT_87015 "Shc phosphorylation by phospho-EGFR:EGF, Mus musculus"
Reactome:REACT_91057 "Shc phosphorylation by phospho-EGFR:EGF, Xenopus tropicalis"
Reactome:REACT_91374 "Shc phosphorylation by phospho-EGFR:EGF, Canis familiaris"
Reactome:REACT_93045 "Shc phosphorylation by phospho-EGFR:EGF, Danio rerio"
Reactome:REACT_95686 "Shc phosphorylation by phospho-EGFR:EGF, Rattus norvegicus"
xref
Reactome:REACT_104778 "SHC1 phosphorylation by phosphorylated EGFR, Taeniopygia guttata"
Reactome:REACT_107918 "SHC1 phosphorylation by phosphorylated EGFR, Gallus gallus"
Reactome:REACT_12592 "SHC1 phosphorylation by phosphorylated EGFR, Homo sapiens"
Reactome:REACT_87015 "SHC1 phosphorylation by phosphorylated EGFR, Mus musculus"
Reactome:REACT_91057 "SHC1 phosphorylation by phosphorylated EGFR, Xenopus tropicalis"
Reactome:REACT_91374 "SHC1 phosphorylation by phosphorylated EGFR, Canis familiaris"
Reactome:REACT_93045 "SHC1 phosphorylation by phosphorylated EGFR, Danio rerio"
Reactome:REACT_95686 "SHC1 phosphorylation by phosphorylated EGFR, Rattus norvegicus"
GO:0004715 : non-membrane spanning protein tyrosine kinase activity
xref
Reactome:REACT_111142 "Jak2 phosphorylates Stat1/Stat3, Mus musculus"
Reactome:REACT_111190 "JAK2 phosphorylation of IRS-1/2, Homo sapiens"
Reactome:REACT_111207 "JAK2 phosphorylates STAT1/STAT3, Homo sapiens"
Reactome:REACT_111211 "Stat5 tyrosine phosphorylation, Mus musculus"
Reactome:REACT_111235 "Lyn activates ERK, Homo sapiens"
Reactome:REACT_112025 "Fgr may phosphorylate p38 MAPK, Dictyostelium discoideum"
Reactome:REACT_112421 "Fgr may phosphorylate p38 MAPK, Drosophila melanogaster"
Reactome:REACT_112972 "Fgr may phosphorylate p38 MAPK, Oryza sativa"
Reactome:REACT_113743 "Fgr may phosphorylate p38 MAPK, Arabidopsis thaliana"
Reactome:REACT_27185 "SHP2 is phosphorylated, Homo sapiens"
GO:0004721 : phosphoprotein phosphatase activity
xref
Reactome:REACT_107782 "Pp2a mediated localization of Rb protein in chromatin, Danio rerio"
Reactome:REACT_28065 "Pp2a mediated localization of Rb protein in chromatin, Arabidopsis thaliana"
Reactome:REACT_79518 "Hypophosphorylation of RNA Pol II CTD by FCP1P protein, Saccharomyces cerevisiae"
Reactome:REACT_80852 "Dephosphorylation of nuclear Cyclin A:phosph-Cdc2 complexes, Sus scrofa"
Reactome:REACT_82328 "Dephosphorylation of phospho-Cdh1, Saccharomyces cerevisiae"
Reactome:REACT_83901 "Pp2a mediated localization of Rb protein in chromatin, Gallus gallus"
Reactome:REACT_88974 "Hypophosphorylation of RNA Pol II CTD by FCP1P protein, Canis familiaris"
Reactome:REACT_92030 "Hypophosphorylation of RNA Pol II CTD by FCP1P protein, Bos taurus"
Reactome:REACT_92277 "Pp2a mediated localization of Rb protein in chromatin, Bos taurus"
Reactome:REACT_95002 "Pp2a mediated localization of Rb protein in chromatin, Sus scrofa"
Reactome:REACT_95610 "Dephosphorylation of cyclin B2:phospho-Cdc2 (Thr 14) by Cdc25, Sus scrofa"
Reactome:REACT_96195 "Pp2a mediated localization of Rb protein in chromatin, Rattus norvegicus"
Reactome:REACT_96431 "Pp2a mediated localization of Rb protein in chromatin, Oryza sativa"
xref
Reactome:REACT_111148 "Dephosphorylation of p107 (RBL1) by PP2A, Homo sapiens"
Reactome:REACT_111170 "Dephosphorylation of p130 (RBL2) by PP2A, Homo sapiens"
Reactome:REACT_112020 "Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A, Drosophila melanogaster"
Reactome:REACT_112348 "Dephosphorylation of cyclin B2:phospho-Cdc2 (Thr 14) by Cdc25, Saccharomyces cerevisiae"
Reactome:REACT_112617 "Dephosphorylation of cytoplasmic Cyclin B1:phospho-Cdc2 (Thr 14, Tyr 15) complexes by Cdc25 phosphatases, Saccharomyces cerevisiae"
Reactome:REACT_112795 "Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A, Saccharomyces cerevisiae"
Reactome:REACT_112811 "Pp2a mediated localization of Rb protein in chromatin, Xenopus tropicalis"
Reactome:REACT_112981 "Dephosphorylation of cyclin B2:phospho-Cdc2 (Thr 14) by Cdc25, Schizosaccharomyces pombe"
Reactome:REACT_113855 "Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases, Schizosaccharomyces pombe"
Reactome:REACT_114200 "Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A, Schizosaccharomyces pombe"
Reactome:REACT_114550 "Dephosphorylation of cytoplasmic Cyclin B1:phospho-Cdc2 (Thr 14, Tyr 15) complexes by Cdc25 phosphatases, Schizosaccharomyces pombe"
Reactome:REACT_115084 "Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases, Saccharomyces cerevisiae"
Reactome:REACT_78414 "Hypophosphorylation of RNA Pol II CTD by FCP1P protein, Saccharomyces cerevisiae"
Reactome:REACT_98946 "Dephosphorylation of phospho-Cdh1, Saccharomyces cerevisiae"
GO:0004722 : protein serine/threonine phosphatase activity
xref
Reactome:REACT_106486 "AMPK is dephosphorylated, Bos taurus"
Reactome:REACT_28811 "PHLPP dephosphorylates S473 in AKT, Caenorhabditis elegans"
Reactome:REACT_80063 "DARPP-32 is dephosphorylated on Thr34 by PP2B, Sus scrofa"
xref
Reactome:REACT_108076 "DARPP-32 is dephosphorylated on Thr34 by PP2B, Sus scrofa"
Reactome:REACT_111094 "PPA2A dephosphorylates SPRY2, Homo sapiens"
Reactome:REACT_112210 "DARPP-32 is dephosphorylated on Thr34 by PP2B, Rattus norvegicus"
Reactome:REACT_112525 "PHLPP dephosphorylates S473 in AKT, Gallus gallus"
Reactome:REACT_112659 "AMPK is dephosphorylated, Saccharomyces cerevisiae"
Reactome:REACT_113935 "PHLPP dephosphorylates S473 in AKT, Xenopus tropicalis"
Reactome:REACT_114990 "DARPP-32 is dephosphorylated on Thr34 by PP2B, Xenopus tropicalis"
GO:0004725 : protein tyrosine phosphatase activity
xref
Reactome:REACT_23816 "SHP1 and SHP2 dephosphorylate Bc Y628, Homo sapiens"
Reactome:REACT_82026 "Dephosphorylation of Lck-pY505 by CD45, Sus scrofa"
xref
Reactome:REACT_111038 "Ptp1b dephosphorylates Jak2, Mus musculus"
Reactome:REACT_111048 "SHP1 (PTPN6) dephosphorylates JAK2, Homo sapiens"
Reactome:REACT_111061 "PTP1B dephosphorylates GHR, Homo sapiens"
Reactome:REACT_111128 "PTP1B dephosphorylates JAK2, Homo sapiens"
Reactome:REACT_111157 "SHP2 dephosphorylates SPRY2, Homo sapiens"
Reactome:REACT_111193 "Shp1 (Ptpn6) dephosphorylates Jak2, Mus musculus"
Reactome:REACT_112085 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Oryza sativa"
Reactome:REACT_112153 "Dephosphorylation of inactive SRC by PTPB1, Drosophila melanogaster"
Reactome:REACT_113070 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Caenorhabditis elegans"
Reactome:REACT_114866 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Arabidopsis thaliana"
Reactome:REACT_115220 "ERKs are inactivated by dual-specific phosphatases (DUSPs), Dictyostelium discoideum"
Reactome:REACT_115381 "Dephosphorylation of inactive SRC by PTPB1, Xenopus tropicalis"
Reactome:REACT_23816 "SHP1 and SHP2 dephosphorylate Y628 of IL3RB, Homo sapiens"
GO:0004729 : oxygen-dependent protoporphyrinogen oxidase activity
xref
Reactome:REACT_28216 "Oxidation of protoporphyrinogen IX to protoporphyrin IX, Dictyostelium discoideum"
xref
Reactome:REACT_81276 "Oxidation of protoporphyrinogen IX to protoporphyrin IX, Dictyostelium discoideum"
GO:0004731 : purine-nucleoside phosphorylase activity
xref
Reactome:REACT_83767 "(deoxy)inosine + orthophosphate <=> hypoxanthine + (deoxy)ribose 1-phosphate [NP], Bos taurus"
Reactome:REACT_92324 "guanine + (deoxy)ribose 1-phosphate <=> (deoxy)guanosine + orthophosphate [NP], Saccharomyces cerevisiae"
Reactome:REACT_95388 "hypoxanthine + (deoxy)ribose 1-phosphate <=> (deoxy)inosine + orthophosphate [NP], Saccharomyces cerevisiae"
xref
Reactome:REACT_109206 "guanine + (deoxy)ribose 1-phosphate <=> (deoxy)guanosine + orthophosphate [NP], Saccharomyces cerevisiae"
Reactome:REACT_84275 "hypoxanthine + (deoxy)ribose 1-phosphate <=> (deoxy)inosine + orthophosphate [NP], Saccharomyces cerevisiae"
Reactome:REACT_95751 "(deoxy)inosine + orthophosphate <=> hypoxanthine + (deoxy)ribose 1-phosphate [NP], Bos taurus"
GO:0004735 : pyrroline-5-carboxylate reductase activity
xref
Reactome:REACT_113065 "L-1-pyrroline-5-carboxylate + NADPH + H+ => proline + NADP+, Oryza sativa"
Reactome:REACT_113362 "L-1-pyrroline-5-carboxylate + NADPH + H+ => proline + NADP+, Arabidopsis thaliana"
Reactome:REACT_113421 "L-1-pyrroline-5-carboxylate + NADPH + H+ => proline + NADP+, Plasmodium falciparum"
Reactome:REACT_114311 "L-1-pyrroline-5-carboxylate + NADPH + H+ => proline + NADP+, Sus scrofa"
GO:0004740 : pyruvate dehydrogenase (acetyl-transferring) kinase activity
xref
Reactome:REACT_78327 "PDK-catalyzed phosphorylation (inactivation) of PDC E1 alpha subunit, Schizosaccharomyces pombe"
GO:0004743 : pyruvate kinase activity
xref
Reactome:REACT_94102 "phosphoenolpyruvate + ADP => pyruvate + ATP, Sus scrofa"
xref
Reactome:REACT_112705 "phosphoenolpyruvate + ADP => pyruvate + ATP, Oryza sativa"
Reactome:REACT_114095 "phosphoenolpyruvate + ADP => pyruvate + ATP, Arabidopsis thaliana"
Reactome:REACT_114481 "phosphoenolpyruvate + ADP => pyruvate + ATP, Plasmodium falciparum"
Reactome:REACT_91947 "phosphoenolpyruvate + ADP => pyruvate + ATP, Sus scrofa"
GO:0004748 : ribonucleoside-diphosphate reductase activity
xref
Reactome:REACT_110451 "NDP + reduced glutaredoxin => dNDP + oxidized glutaredoxin + H2O, Saccharomyces cerevisiae"
Reactome:REACT_31285 "NDP + reduced thioredoxin => dNDP + oxidized thioredoxin + H2O, Schizosaccharomyces pombe"
Reactome:REACT_79810 "NDP + reduced glutaredoxin => dNDP + oxidized glutaredoxin + H2O, Schizosaccharomyces pombe"
Reactome:REACT_81083 "NDP + reduced thioredoxin => dNDP + oxidized thioredoxin + H2O, Schizosaccharomyces pombe"
Reactome:REACT_91522 "NDP + reduced thioredoxin => dNDP + oxidized thioredoxin + H2O, Bos taurus"
xref
Reactome:REACT_113565 "NDP + reduced thioredoxin => dNDP + oxidized thioredoxin + H2O, Caenorhabditis elegans"
Reactome:REACT_115326 "NDP + reduced thioredoxin => dNDP + oxidized thioredoxin + H2O, Caenorhabditis elegans"
Reactome:REACT_34006 "NDP + reduced thioredoxin => dNDP + oxidized thioredoxin + H2O, Bos taurus"
GO:0004749 : ribose phosphate diphosphokinase activity
xref
Reactome:REACT_100928 "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate, Taeniopygia guttata"
Reactome:REACT_32768 "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate, Taeniopygia guttata"
Reactome:REACT_79866 "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate, Saccharomyces cerevisiae"
Reactome:REACT_84508 "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate, Bos taurus"
Reactome:REACT_99413 "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate, Sus scrofa"
xref
Reactome:REACT_101576 "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate, Saccharomyces cerevisiae"
Reactome:REACT_113259 "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate, Xenopus tropicalis"
Reactome:REACT_114942 "D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate, Xenopus tropicalis"
Reactome:REACT_31823 "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate, Bos taurus"
Reactome:REACT_94569 "D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate, Sus scrofa"
GO:0004750 : ribulose-phosphate 3-epimerase activity
xref
Reactome:REACT_34090 "xylulose 5-phosphate <=> D-ribulose 5-phosphate, Bos taurus"
xref
Reactome:REACT_113659 "D-ribulose 5-phosphate <=> xylulose 5-phosphate, Sus scrofa"
Reactome:REACT_114208 "xylulose 5-phosphate <=> D-ribulose 5-phosphate, Sus scrofa"
Reactome:REACT_81057 "xylulose 5-phosphate <=> D-ribulose 5-phosphate, Bos taurus"
GO:0004751 : ribose-5-phosphate isomerase activity
xref
Reactome:REACT_110556 "D-ribulose 5-phosphate <=> ribose 5-phosphate, Plasmodium falciparum"
xref
Reactome:REACT_113206 "D-ribulose 5-phosphate <=> ribose 5-phosphate, Arabidopsis thaliana"
Reactome:REACT_114043 "ribose 5-phosphate <=> D-ribulose 5-phosphate, Oryza sativa"
Reactome:REACT_115286 "ribose 5-phosphate <=> D-ribulose 5-phosphate, Arabidopsis thaliana"
Reactome:REACT_115365 "D-ribulose 5-phosphate <=> ribose 5-phosphate, Oryza sativa"
Reactome:REACT_34759 "D-ribulose 5-phosphate <=> ribose 5-phosphate, Plasmodium falciparum"
GO:0004757 : sepiapterin reductase activity
xref
Reactome:REACT_111093 "PTHP is reduced to BH4 by sepiapterin reductase (SPR), Homo sapiens"
Reactome:REACT_111234 "Salvage - Sepiapterin is reduced to BH2, Homo sapiens"
GO:0004758 : serine C-palmitoyltransferase activity
xref
Reactome:REACT_113202 "palmitoyl-CoA + serine => 3-ketosphinganine + CoASH + CO2, Plasmodium falciparum"
GO:0004766 : spermidine synthase activity
xref
Reactome:REACT_29263 "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine, Dictyostelium discoideum"
Reactome:REACT_87445 "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine, Mycobacterium tuberculosis"
xref
Reactome:REACT_31767 "Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine, Dictyostelium discoideum"
GO:0004767 : sphingomyelin phosphodiesterase activity
xref
Reactome:REACT_102767 "Production of ceramide which can activate JNK and other targets, Sus scrofa"
xref
Reactome:REACT_88771 "Production of ceramide which can activate JNK and other targets, Sus scrofa"
GO:0004769 : steroid delta-isomerase activity
xref
Reactome:REACT_32083 "Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol, Bos taurus"
xref
Reactome:REACT_112222 "Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone, Mycobacterium tuberculosis"
Reactome:REACT_112738 "Pregn-5-ene-3,20-dione isomerizes to progesterone, Escherichia coli"
Reactome:REACT_113344 "Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone, Escherichia coli"
Reactome:REACT_113857 "Pregn-5-ene-3,20-dione isomerizes to progesterone, Mycobacterium tuberculosis"
Reactome:REACT_113969 "DHA isomerizes to 4-Androstene3,17-dione, Mycobacterium tuberculosis"
Reactome:REACT_114179 "DHA isomerizes to 4-Androstene3,17-dione, Escherichia coli"
Reactome:REACT_114390 "Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol, Arabidopsis thaliana"
Reactome:REACT_114902 "Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol, Oryza sativa"
Reactome:REACT_93338 "Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol, Bos taurus"
GO:0004775 : succinate-CoA ligase (ADP-forming) activity
xref
Reactome:REACT_106724 "ADP + Orthophosphate + Succinyl-CoA <=> ATP + Succinate + CoA, Dictyostelium discoideum"
Reactome:REACT_34061 "ADP + Orthophosphate + Succinyl-CoA <=> ATP + Succinate + CoA, Saccharomyces cerevisiae"
Reactome:REACT_79399 "ADP + Orthophosphate + Succinyl-CoA <=> ATP + Succinate + CoA, Schizosaccharomyces pombe"
Reactome:REACT_87261 "ADP + Orthophosphate + Succinyl-CoA <=> ATP + Succinate + CoA, Plasmodium falciparum"
GO:0004776 : succinate-CoA ligase (GDP-forming) activity
xref
Reactome:REACT_31838 "GDP + Orthophosphate + Succinyl-CoA <=> GTP + Succinate + CoA, Dictyostelium discoideum"
Reactome:REACT_77973 "GDP + Orthophosphate + Succinyl-CoA <=> GTP + Succinate + CoA, Oryza sativa"
Reactome:REACT_80781 "GDP + Orthophosphate + Succinyl-CoA <=> GTP + Succinate + CoA, Arabidopsis thaliana"
GO:0004781 : sulfate adenylyltransferase (ATP) activity
xref
Reactome:REACT_106092 "ATP + sulfate => adenylyl sulfate (APS) + pyrophosphate, Saccharomyces cerevisiae"
Reactome:REACT_33321 "ATP + sulfate => adenylyl sulfate (APS) + pyrophosphate, Schizosaccharomyces pombe"
xref
Reactome:REACT_112565 "ATP + sulfate => adenylyl sulfate (APS) + pyrophosphate, Escherichia coli"
GO:0004788 : thiamine diphosphokinase activity
xref
Reactome:REACT_101961 "Thiamin is pyrophosphorylated, Bos taurus"
xref
Reactome:REACT_29244 "Thiamin is pyrophosphorylated, Bos taurus"
GO:0004791 : thioredoxin-disulfide reductase activity
xref
Reactome:REACT_114582 "thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+, Caenorhabditis elegans"
GO:0004801 : sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity
xref
Reactome:REACT_101200 "D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate, Saccharomyces cerevisiae"
Reactome:REACT_93089 "D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate, Schizosaccharomyces pombe"
xref
Reactome:REACT_100775 "D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate, Schizosaccharomyces pombe"
Reactome:REACT_105812 "D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate, Saccharomyces cerevisiae"
GO:0004806 : triglyceride lipase activity
xref
Reactome:REACT_96952 "triacylglycerol + H2O -> diacylglycerol + fatty acid, Drosophila melanogaster"
xref
Reactome:REACT_113800 "triacylglycerol + H2O -> diacylglycerol + fatty acid, Danio rerio"
GO:0004807 : triose-phosphate isomerase activity
xref
Reactome:REACT_107741 "D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate, Oryza sativa"
Reactome:REACT_89134 "dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate, Arabidopsis thaliana"
Reactome:REACT_94073 "dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate, Schizosaccharomyces pombe"
Reactome:REACT_96255 "D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate, Arabidopsis thaliana"
Reactome:REACT_99351 "dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate, Oryza sativa"
xref
Reactome:REACT_32420 "dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate, Schizosaccharomyces pombe"
GO:0004813 : alanine-tRNA ligase activity
xref
Reactome:REACT_80161 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate, Bos taurus"
xref
Reactome:REACT_112870 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate, Staphylococcus aureus N315"
Reactome:REACT_112886 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate, Caenorhabditis elegans"
Reactome:REACT_113119 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate, Oryza sativa"
Reactome:REACT_114744 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate, Arabidopsis thaliana"
Reactome:REACT_114834 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate, Arabidopsis thaliana"
Reactome:REACT_114863 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate, Drosophila melanogaster"
Reactome:REACT_114945 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate, Oryza sativa"
Reactome:REACT_89789 "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate, Bos taurus"
GO:0004814 : arginine-tRNA ligase activity
xref
Reactome:REACT_110209 "arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate, Staphylococcus aureus N315"
Reactome:REACT_30179 "arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate, Mycobacterium tuberculosis"
Reactome:REACT_98705 "arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate, Bos taurus"
Reactome:REACT_99992 "arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate, Dictyostelium discoideum"
xref
Reactome:REACT_101377 "arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate, Bos taurus"
Reactome:REACT_101912 "arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate, Dictyostelium discoideum"
Reactome:REACT_114854 "arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate, Arabidopsis thaliana"
GO:0004815 : aspartate-tRNA ligase activity
xref
Reactome:REACT_109531 "aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate, Plasmodium falciparum"
Reactome:REACT_28643 "aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate, Dictyostelium discoideum"
Reactome:REACT_99417 "aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate, Bos taurus"
xref
Reactome:REACT_112613 "aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate, Arabidopsis thaliana"
Reactome:REACT_31439 "aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate, Bos taurus"
Reactome:REACT_93154 "aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate, Dictyostelium discoideum"
GO:0004816 : asparagine-tRNA ligase activity
xref
Reactome:REACT_84108 "asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate, Staphylococcus aureus N315"
xref
Reactome:REACT_115176 "asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate, Staphylococcus aureus N315"
GO:0004817 : cysteine-tRNA ligase activity
xref
Reactome:REACT_100589 "cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate, Sus scrofa"
Reactome:REACT_105688 "cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate, Mycobacterium tuberculosis"
Reactome:REACT_90834 "cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate, Mycobacterium tuberculosis"
xref
Reactome:REACT_33699 "cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate, Sus scrofa"
GO:0004818 : glutamate-tRNA ligase activity
xref
Reactome:REACT_33213 "glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate, Escherichia coli"
Reactome:REACT_79886 "glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate, Bos taurus"
Reactome:REACT_82819 "glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate, Dictyostelium discoideum"
xref
Reactome:REACT_112102 "glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate, Arabidopsis thaliana"
Reactome:REACT_79594 "glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate, Dictyostelium discoideum"
Reactome:REACT_99054 "glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate, Bos taurus"
GO:0004819 : glutamine-tRNA ligase activity
xref
Reactome:REACT_114946 "glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate, Arabidopsis thaliana"
GO:0004820 : glycine-tRNA ligase activity
xref
Reactome:REACT_100213 "glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate, Dictyostelium discoideum"
Reactome:REACT_98118 "glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate, Bos taurus"
xref
Reactome:REACT_104151 "glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate, Bos taurus"
Reactome:REACT_29415 "glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate, Dictyostelium discoideum"
GO:0004821 : histidine-tRNA ligase activity
xref
Reactome:REACT_79169 "histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate, Bos taurus"
Reactome:REACT_86803 "histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate, Dictyostelium discoideum"
Reactome:REACT_87118 "histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate, Bos taurus"
xref
Reactome:REACT_104519 "histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate, Bos taurus"
Reactome:REACT_30681 "histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate, Bos taurus"
Reactome:REACT_86389 "histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate, Dictyostelium discoideum"
GO:0004822 : isoleucine-tRNA ligase activity
xref
Reactome:REACT_112356 "isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate, Plasmodium falciparum"
Reactome:REACT_112543 "isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate, Arabidopsis thaliana"
GO:0004823 : leucine-tRNA ligase activity
xref
Reactome:REACT_113044 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate, Arabidopsis thaliana"
GO:0004824 : lysine-tRNA ligase activity
xref
Reactome:REACT_112280 "lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate, Staphylococcus aureus N315"
Reactome:REACT_112322 "lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate, Arabidopsis thaliana"
Reactome:REACT_113853 "lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate, Arabidopsis thaliana"
GO:0004825 : methionine-tRNA ligase activity
xref
Reactome:REACT_112098 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Dictyostelium discoideum"
Reactome:REACT_112796 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Sus scrofa"
Reactome:REACT_112814 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Oryza sativa"
Reactome:REACT_112913 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Rattus norvegicus"
Reactome:REACT_112985 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Saccharomyces cerevisiae"
Reactome:REACT_113327 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Schizosaccharomyces pombe"
Reactome:REACT_113473 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Bos taurus"
Reactome:REACT_113488 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Taeniopygia guttata"
Reactome:REACT_113546 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Arabidopsis thaliana"
Reactome:REACT_113638 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Plasmodium falciparum"
Reactome:REACT_113646 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Danio rerio"
Reactome:REACT_113871 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Arabidopsis thaliana"
Reactome:REACT_114216 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Mus musculus"
Reactome:REACT_114281 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Canis familiaris"
Reactome:REACT_114409 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Gallus gallus"
Reactome:REACT_114525 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Drosophila melanogaster"
Reactome:REACT_114728 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Staphylococcus aureus N315"
Reactome:REACT_114871 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Xenopus tropicalis"
Reactome:REACT_114923 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Mycobacterium tuberculosis"
Reactome:REACT_115107 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Caenorhabditis elegans"
Reactome:REACT_115242 "methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate, Escherichia coli"
GO:0004826 : phenylalanine-tRNA ligase activity
xref
Reactome:REACT_34242 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Caenorhabditis elegans"
xref
Reactome:REACT_112009 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Oryza sativa"
Reactome:REACT_112342 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Gallus gallus"
Reactome:REACT_112442 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Schizosaccharomyces pombe"
Reactome:REACT_112609 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Arabidopsis thaliana"
Reactome:REACT_113739 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Drosophila melanogaster"
Reactome:REACT_114559 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Caenorhabditis elegans"
Reactome:REACT_114632 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Plasmodium falciparum"
Reactome:REACT_114633 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Saccharomyces cerevisiae"
Reactome:REACT_114689 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Dictyostelium discoideum"
Reactome:REACT_115103 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Xenopus tropicalis"
Reactome:REACT_77960 "phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate, Caenorhabditis elegans"
GO:0004827 : proline-tRNA ligase activity
xref
Reactome:REACT_85055 "proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate, Schizosaccharomyces pombe"
xref
Reactome:REACT_113180 "proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate, Arabidopsis thaliana"
Reactome:REACT_34251 "proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate, Schizosaccharomyces pombe"
GO:0004828 : serine-tRNA ligase activity
xref
Reactome:REACT_77123 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate, Staphylococcus aureus N315"
Reactome:REACT_85157 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate, Mycobacterium tuberculosis"
Reactome:REACT_90889 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate, Escherichia coli"
Reactome:REACT_98765 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate, Bos taurus"
xref
Reactome:REACT_105286 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate, Bos taurus"
Reactome:REACT_112205 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate, Staphylococcus aureus N315"
Reactome:REACT_113323 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate, Mycobacterium tuberculosis"
Reactome:REACT_114211 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate, Plasmodium falciparum"
Reactome:REACT_115009 "serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate, Escherichia coli"
GO:0004829 : threonine-tRNA ligase activity
xref
Reactome:REACT_106118 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Drosophila melanogaster"
Reactome:REACT_29947 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Schizosaccharomyces pombe"
Reactome:REACT_33550 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Schizosaccharomyces pombe"
Reactome:REACT_33563 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Saccharomyces cerevisiae"
Reactome:REACT_33606 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Caenorhabditis elegans"
Reactome:REACT_78111 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Dictyostelium discoideum"
Reactome:REACT_83289 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Drosophila melanogaster"
Reactome:REACT_90829 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Saccharomyces cerevisiae"
Reactome:REACT_97397 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Caenorhabditis elegans"
Reactome:REACT_99099 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Dictyostelium discoideum"
xref
Reactome:REACT_112924 "threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate, Xenopus tropicalis"
GO:0004830 : tryptophan-tRNA ligase activity
xref
Reactome:REACT_92679 "tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate, Dictyostelium discoideum"
xref
Reactome:REACT_104142 "tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate, Dictyostelium discoideum"
GO:0004831 : tyrosine-tRNA ligase activity
xref
Reactome:REACT_113020 "tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate, Drosophila melanogaster"
Reactome:REACT_113391 "tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate, Escherichia coli"
GO:0004832 : valine-tRNA ligase activity
xref
Reactome:REACT_114299 "valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate, Mycobacterium tuberculosis"
GO:0004838 : L-tyrosine:2-oxoglutarate aminotransferase activity
xref
Reactome:REACT_83064 "tyrosine + alpha-ketoglutarate <=> p-hydroxyphenylpyruvate + glutamate, Bos taurus"
xref
Reactome:REACT_96541 "tyrosine + alpha-ketoglutarate <=> p-hydroxyphenylpyruvate + glutamate, Bos taurus"
GO:0004842 : ubiquitin-protein ligase activity
xref
Reactome:REACT_100102 "Ubiquitination of stimulated EGFR (Cbl:Grb2), Rattus norvegicus"
Reactome:REACT_100856 "Cbl ubiquitinates Sprouty, Danio rerio"
Reactome:REACT_101051 "Multiubiquitination of APC/C-associated Cdh1, Arabidopsis thaliana"
Reactome:REACT_101216 "Cbl ubiquitinates Sprouty, Rattus norvegicus"
Reactome:REACT_101217 "Cbl binds and ubiquitinates Phospho-Sprouty, Rattus norvegicus"
Reactome:REACT_101618 "Ubiquitination of Cyclin A by APC/C:Cdc20 complex, Arabidopsis thaliana"
Reactome:REACT_101822 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Mus musculus"
Reactome:REACT_102841 "Ubiquitination of stimulated EGFR (Cbl:Grb2), Bos taurus"
Reactome:REACT_103376 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Taeniopygia guttata"
Reactome:REACT_103721 "Cbl-mediated ubiquitination of CIN85, Rattus norvegicus"
Reactome:REACT_104593 "Autoubiquitination of phospho-COP1(Ser-387 ), Arabidopsis thaliana"
Reactome:REACT_104803 "Cbl ubiquitinates Sprouty, Canis familiaris"
Reactome:REACT_106407 "Cbl binds and ubiquitinates Phospho-Sprouty, Mus musculus"
Reactome:REACT_106416 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Sus scrofa"
Reactome:REACT_106527 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Gallus gallus"
Reactome:REACT_106550 "Ubiquitination of Emi1 by SCF-beta-TrCP, Caenorhabditis elegans"
Reactome:REACT_107859 "Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex, Arabidopsis thaliana"
Reactome:REACT_108400 "Ubiquitination of stimulated EGFR (Cbl), Taeniopygia guttata"
Reactome:REACT_109798 "Cbl-mediated ubiquitination of CIN85, Mus musculus"
Reactome:REACT_12381 "Cbl ubiquitinates Sprouty, Homo sapiens"
Reactome:REACT_12432 "Cbl binds and ubiquitinates Phospho-Sprouty, Homo sapiens"
Reactome:REACT_12451 "Cbl escapes Cdc42-mediated inhibition by down-regulating the adaptor molecule betaPix, Homo sapiens"
Reactome:REACT_12515 "Ubiquitination of stimulated EGFR (Cbl), Homo sapiens"
Reactome:REACT_12520 "Cbl-mediated ubiquitination of CIN85, Homo sapiens"
Reactome:REACT_12562 "Ubiquitination of stimulated EGFR (Cbl:Grb2), Homo sapiens"
Reactome:REACT_29045 "Cbl ubiquitinates Sprouty, Xenopus tropicalis"
Reactome:REACT_32642 "Cbl ubiquitinates Sprouty, Taeniopygia guttata"
Reactome:REACT_33488 "Cbl binds and ubiquitinates Phospho-Sprouty, Danio rerio"
Reactome:REACT_34698 "Ubiquitination of Securin by phospho-APC/C:Cdc20 complex, Arabidopsis thaliana"
Reactome:REACT_62571 "Ubiquitination of stimulated EGFR (Cbl:Grb2), Gallus gallus"
Reactome:REACT_6786 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Homo sapiens"
Reactome:REACT_78171 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Canis familiaris"
Reactome:REACT_78373 "Ubiquitination of stimulated EGFR (Cbl), Xenopus tropicalis"
Reactome:REACT_80572 "Cbl-mediated ubiquitination of CIN85, Taeniopygia guttata"
Reactome:REACT_80813 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Rattus norvegicus"
Reactome:REACT_81041 "Cbl escapes Cdc42-mediated inhibition by down-regulating the adaptor molecule betaPix, Mus musculus"
Reactome:REACT_81526 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Bos taurus"
Reactome:REACT_82956 "Cbl-mediated ubiquitination of CIN85, Bos taurus"
Reactome:REACT_84282 "Ubiquitination of stimulated EGFR (Cbl), Danio rerio"
Reactome:REACT_84826 "Ubiquitination of stimulated EGFR (Cbl), Mus musculus"
Reactome:REACT_85337 "Cbl binds and ubiquitinates Phospho-Sprouty, Canis familiaris"
Reactome:REACT_85348 "Cbl-mediated ubiquitination of CIN85, Gallus gallus"
Reactome:REACT_86879 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Danio rerio"
Reactome:REACT_88011 "Ubiquitination of Emi1 by SCF-beta-TrCP, Schizosaccharomyces pombe"
Reactome:REACT_88911 "Cbl ubiquitinates Sprouty, Mus musculus"
Reactome:REACT_89086 "Ubiquitination of stimulated EGFR (Cbl), Canis familiaris"
Reactome:REACT_89324 "Cbl-mediated ubiquitination of CIN85, Danio rerio"
Reactome:REACT_90441 "Cbl-mediated ubiquitination of CIN85, Canis familiaris"
Reactome:REACT_91446 "Ubiquitination of stimulated EGFR (Cbl:Grb2), Xenopus tropicalis"
Reactome:REACT_91516 "Ubiquitination of PER Proteins, Caenorhabditis elegans"
Reactome:REACT_92278 "Cbl escapes Cdc42-mediated inhibition by down-regulating the adaptor molecule betaPix, Rattus norvegicus"
Reactome:REACT_92445 "Cbl binds and ubiquitinates Phospho-Sprouty, Xenopus tropicalis"
Reactome:REACT_93808 "Ubiquitination of stimulated EGFR (Cbl:Grb2), Danio rerio"
Reactome:REACT_93940 "Cbl-mediated ubiquitination of CIN85, Drosophila melanogaster"
Reactome:REACT_94165 "Cbl escapes Cdc42-mediated inhibition by down-regulating the adaptor molecule betaPix, Danio rerio"
Reactome:REACT_94265 "Cbl-mediated ubiquitination of CIN85, Caenorhabditis elegans"
Reactome:REACT_94525 "Cbl escapes Cdc42-mediated inhibition by down-regulating the adaptor molecule betaPix, Xenopus tropicalis"
Reactome:REACT_94564 "Cbl escapes Cdc42-mediated inhibition by down-regulating the adaptor molecule betaPix, Taeniopygia guttata"
Reactome:REACT_94789 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Drosophila melanogaster"
Reactome:REACT_95866 "Ubiquitination of stimulated EGFR (Cbl:Grb2), Taeniopygia guttata"
Reactome:REACT_96059 "Ubiquitination of stimulated EGFR (Cbl:Grb2), Canis familiaris"
Reactome:REACT_96591 "Cbl-mediated ubiquitination of CIN85, Xenopus tropicalis"
Reactome:REACT_96771 "Ubiquitin-dependent degradation controls basal levels of R-SMAD, Xenopus tropicalis"
Reactome:REACT_97242 "Cbl binds and ubiquitinates Phospho-Sprouty, Taeniopygia guttata"
Reactome:REACT_97494 "Ubiquitination of stimulated EGFR (Cbl:Grb2), Mus musculus"
Reactome:REACT_99285 "Ubiquitination of stimulated EGFR (Cbl), Rattus norvegicus"
xref
Reactome:REACT_100102 "Ubiquitination of stimulated EGFR (CBL:GRB2), Rattus norvegicus"
Reactome:REACT_100856 "CBL ubiquitinates Sprouty, Danio rerio"
Reactome:REACT_101216 "CBL ubiquitinates Sprouty, Rattus norvegicus"
Reactome:REACT_101217 "CBL binds and ubiquitinates phosphorylated Sprouty, Rattus norvegicus"
Reactome:REACT_101822 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Mus musculus"
Reactome:REACT_102841 "Ubiquitination of stimulated EGFR (CBL:GRB2), Bos taurus"
Reactome:REACT_103376 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Taeniopygia guttata"
Reactome:REACT_103721 "CBL-mediated ubiquitination of CIN85, Rattus norvegicus"
Reactome:REACT_104803 "CBL ubiquitinates Sprouty, Canis familiaris"
Reactome:REACT_106407 "CBL binds and ubiquitinates phosphorylated Sprouty, Mus musculus"
Reactome:REACT_106416 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Sus scrofa"
Reactome:REACT_106527 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Gallus gallus"
Reactome:REACT_109798 "CBL-mediated ubiquitination of CIN85, Mus musculus"
Reactome:REACT_111089 "Ubiquitination of p130 (RBL2) by SCF (Skp2), Homo sapiens"
Reactome:REACT_111141 "Phosphorylated SPRY2 is ubiquitinated by CBL, Homo sapiens"
Reactome:REACT_111231 "CBL ubiquitinates FRS2 and FGFR, Homo sapiens"
Reactome:REACT_112355 "Auto-ubiquitination of TRAF6, Bos taurus"
Reactome:REACT_112414 "Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling, Danio rerio"
Reactome:REACT_112448 "Ubiquitination of NEMO by TRAF6, Xenopus tropicalis"
Reactome:REACT_112669 "CBL ubiquitinates Sprouty, Drosophila melanogaster"
Reactome:REACT_113192 "CBL ubiquitinates Sprouty, Bos taurus"
Reactome:REACT_113956 "Monoubiquitination of FANCI by the FA ubiquitin ligase complex, Xenopus tropicalis"
Reactome:REACT_114042 "Auto-ubiquitination of TRAF6, Gallus gallus"
Reactome:REACT_114074 "CBL ubiquitinates Sprouty, Gallus gallus"
Reactome:REACT_114376 "Ubiquitination of Cyclin A by APC/C:Cdc20 complex, Oryza sativa"
Reactome:REACT_114678 "Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling, Danio rerio"
Reactome:REACT_115172 "Multiubiquitination of Nek2A, Dictyostelium discoideum"
Reactome:REACT_115175 "Ubiquitination of NEMO by TRAF6, Bos taurus"
Reactome:REACT_12381 "CBL ubiquitinates Sprouty, Homo sapiens"
Reactome:REACT_12432 "CBL binds and ubiquitinates phosphorylated Sprouty, Homo sapiens"
Reactome:REACT_12451 "CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix, Homo sapiens"
Reactome:REACT_12515 "Ubiquitination of stimulated EGFR (CBL), Homo sapiens"
Reactome:REACT_12520 "CBL-mediated ubiquitination of CIN85, Homo sapiens"
Reactome:REACT_12562 "Ubiquitination of stimulated EGFR (CBL:GRB2), Homo sapiens"
Reactome:REACT_29045 "CBL ubiquitinates Sprouty, Xenopus tropicalis"
Reactome:REACT_32642 "CBL ubiquitinates Sprouty, Taeniopygia guttata"
Reactome:REACT_33488 "CBL binds and ubiquitinates phosphorylated Sprouty, Danio rerio"
Reactome:REACT_62571 "Ubiquitination of stimulated EGFR (CBL:GRB2), Gallus gallus"
Reactome:REACT_6786 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Homo sapiens"
Reactome:REACT_78171 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Canis familiaris"
Reactome:REACT_78373 "Ubiquitination of stimulated EGFR (CBL), Xenopus tropicalis"
Reactome:REACT_80572 "CBL-mediated ubiquitination of CIN85, Taeniopygia guttata"
Reactome:REACT_80813 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Rattus norvegicus"
Reactome:REACT_81041 "CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix, Mus musculus"
Reactome:REACT_81526 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Bos taurus"
Reactome:REACT_82956 "CBL-mediated ubiquitination of CIN85, Bos taurus"
Reactome:REACT_84282 "Ubiquitination of stimulated EGFR (CBL), Danio rerio"
Reactome:REACT_84826 "Ubiquitination of stimulated EGFR (CBL), Mus musculus"
Reactome:REACT_85337 "CBL binds and ubiquitinates phosphorylated Sprouty, Canis familiaris"
Reactome:REACT_85348 "CBL-mediated ubiquitination of CIN85, Gallus gallus"
Reactome:REACT_86879 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Danio rerio"
Reactome:REACT_88911 "CBL ubiquitinates Sprouty, Mus musculus"
Reactome:REACT_89086 "Ubiquitination of stimulated EGFR (CBL), Canis familiaris"
Reactome:REACT_89324 "CBL-mediated ubiquitination of CIN85, Danio rerio"
Reactome:REACT_90441 "CBL-mediated ubiquitination of CIN85, Canis familiaris"
Reactome:REACT_91446 "Ubiquitination of stimulated EGFR (CBL:GRB2), Xenopus tropicalis"
Reactome:REACT_92278 "CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix, Rattus norvegicus"
Reactome:REACT_92445 "CBL binds and ubiquitinates phosphorylated Sprouty, Xenopus tropicalis"
Reactome:REACT_93808 "Ubiquitination of stimulated EGFR (CBL:GRB2), Danio rerio"
Reactome:REACT_93940 "CBL-mediated ubiquitination of CIN85, Drosophila melanogaster"
Reactome:REACT_94165 "CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix, Danio rerio"
Reactome:REACT_94525 "CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix, Xenopus tropicalis"
Reactome:REACT_94789 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Drosophila melanogaster"
Reactome:REACT_95866 "Ubiquitination of stimulated EGFR (CBL:GRB2), Taeniopygia guttata"
Reactome:REACT_96059 "Ubiquitination of stimulated EGFR (CBL:GRB2), Canis familiaris"
Reactome:REACT_96591 "CBL-mediated ubiquitination of CIN85, Xenopus tropicalis"
Reactome:REACT_96771 "Ubiquitin-dependent degradation controls basal levels of SMAD2/3, Xenopus tropicalis"
Reactome:REACT_97494 "Ubiquitination of stimulated EGFR (CBL:GRB2), Mus musculus"
Reactome:REACT_99285 "Ubiquitination of stimulated EGFR (CBL), Rattus norvegicus"
GO:0004844 : uracil DNA N-glycosylase activity
xref
Reactome:REACT_79040 "Cleavage of uracil by UNG2 glycosylase, Danio rerio"
Reactome:REACT_83829 "Cleavage of uracil by UNG2 glycosylase, Saccharomyces cerevisiae"
Reactome:REACT_84632 "Cleavage of uracil by UNG2 glycosylase, Schizosaccharomyces pombe"
Reactome:REACT_85604 "Cleavage of 5-hydroxyluracil by UNG2 glycosylase, Schizosaccharomyces pombe"
Reactome:REACT_87147 "Cleavage of 5-hydroxyluracil by UNG2 glycosylase, Saccharomyces cerevisiae"
Reactome:REACT_92529 "Cleavage of 5-hydroxyluracil by UNG2 glycosylase, Danio rerio"
GO:0004855 : xanthine oxidase activity
xref
Reactome:REACT_108625 "Xanthine + H2O + O2 => Urate + H2O2, Bos taurus"
xref
Reactome:REACT_113063 "Hypoxanthine + H2O + O2 => Xanthine + H2O2, Escherichia coli"
Reactome:REACT_113246 "Xanthine + H2O + O2 => Urate + H2O2, Escherichia coli"
Reactome:REACT_113574 "Xanthine + H2O + O2 => Urate + H2O2, Mycobacterium tuberculosis"
Reactome:REACT_114235 "Hypoxanthine + H2O + O2 => Xanthine + H2O2, Dictyostelium discoideum"
Reactome:REACT_114723 "Xanthine + H2O + O2 => Urate + H2O2, Dictyostelium discoideum"
Reactome:REACT_115203 "Hypoxanthine + H2O + O2 => Xanthine + H2O2, Mycobacterium tuberculosis"
Reactome:REACT_87777 "Xanthine + H2O + O2 => Urate + H2O2, Bos taurus"
GO:0004862 : cAMP-dependent protein kinase inhibitor activity
xref
Reactome:REACT_114726 "DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function, Xenopus tropicalis"
GO:0004867 : serine-type endopeptidase inhibitor activity
xref
Reactome:REACT_110581 "urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 2 (PAI-2) -> PAI-2:urokinase plasminogen activator (two-chain):uPAR, Sus scrofa"
Reactome:REACT_32455 "fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1, Caenorhabditis elegans"
Reactome:REACT_33331 "fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1, Caenorhabditis elegans"
Reactome:REACT_97566 "alpha-2-antiplasmin + plasmin -> alpha-2-antiplasmin:plasmin, Sus scrofa"
xref
Reactome:REACT_106218 "alpha-2-antiplasmin + plasmin -> alpha-2-antiplasmin:plasmin, Sus scrofa"
Reactome:REACT_113222 "alpha-2-antiplasmin + plasmin -> alpha-2-antiplasmin:plasmin, Xenopus tropicalis"
Reactome:REACT_83397 "urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 2 (PAI-2) -> PAI-2:urokinase plasminogen activator (two-chain):uPAR, Sus scrofa"
GO:0004875 : complement receptor activity
is_a
GO:0001848
relationship
has_part GO:0001848
GO:0004877 : complement component C3b receptor activity
is_a
GO:0001850
relationship
has_part GO:0001850
has_part GO:0001851
GO:0004878 : complement component C5a receptor activity
is_a
GO:0001856
relationship
has_part GO:0001856
GO:0004880 : juvenile hormone receptor activity
relationship
has_part GO:0005500
GO:0004882 : androgen receptor activity
relationship
has_part GO:0005497
GO:0004887 : thyroid hormone receptor activity
relationship
has_part GO:0070324
GO:0004896 : cytokine receptor activity
is_a
GO:0019955
relationship
has_part GO:0019955
GO:0004897 : ciliary neurotrophic factor receptor activity
relationship
has_part GO:0070119
GO:0004901 : granulocyte macrophage colony-stimulating factor receptor activity
relationship
has_part GO:0042021
GO:0004902 : granulocyte colony-stimulating factor receptor activity
relationship
has_part GO:0051916
GO:0004904 : interferon receptor activity
is_a
GO:0019961
relationship
has_part GO:0019961
GO:0004905 : type I interferon receptor activity
is_a
GO:0019962
relationship
has_part GO:0019962
GO:0004906 : interferon-gamma receptor activity
is_a
GO:0019964
relationship
has_part GO:0019964
GO:0004908 : interleukin-1 receptor activity
is_a
GO:0019966
relationship
has_part GO:0019966
GO:0004911 : interleukin-2 receptor activity
is_a
GO:0019976
relationship
has_part GO:0019976
GO:0004912 : interleukin-3 receptor activity
is_a
GO:0019978
relationship
has_part GO:0019978
GO:0004913 : interleukin-4 receptor activity
is_a
GO:0019979
relationship
has_part GO:0019979
GO:0004914 : interleukin-5 receptor activity
is_a
GO:0019980
relationship
has_part GO:0019980
GO:0004915 : interleukin-6 receptor activity
is_a
GO:0019981
relationship
has_part GO:0019981
GO:0004917 : interleukin-7 receptor activity
is_a
GO:0019982
relationship
has_part GO:0019982
GO:0004918 : interleukin-8 receptor activity
is_a
GO:0019959
relationship
has_part GO:0019959
GO:0004919 : interleukin-9 receptor activity
is_a
GO:0019983
relationship
has_part GO:0019983
GO:0004920 : interleukin-10 receptor activity
is_a
GO:0019969
relationship
has_part GO:0019969
GO:0004921 : interleukin-11 receptor activity
is_a
GO:0019970
relationship
has_part GO:0019970
GO:0004948 : calcitonin receptor activity
relationship
has_part GO:0032841
GO:0004950 : chemokine receptor activity
is_a
GO:0019956
is_a
GO:0004896
relationship
has_part GO:0019956
GO:0004952 : dopamine receptor activity
is_a
GO:0035240
relationship
has_part GO:0035240
GO:0004968 : gonadotropin-releasing hormone receptor activity
relationship
has_part GO:0051448
GO:0004978 : corticotropin receptor activity
is_a
GO:0042562
relationship
has_part GO:0042562
GO:0004980 : melanocyte-stimulating hormone receptor activity
is_a
GO:0042562
relationship
has_part GO:0042562
GO:0005030 : neurotrophin receptor activity
is_a
GO:0043121
relationship
has_part GO:0043121
GO:0005031 : tumor necrosis factor-activated receptor activity
name
tumor necrosis factor receptor activity
is_a
GO:0043120
name
tumor necrosis factor-activated receptor activity
synonym
"tumor necrosis factor receptor activity" EXACT [GOC:bf, GOC:signaling]
relationship
has_part GO:0043120
GO:0005040 : decoy death receptor activity
is_a
GO:0005488
relationship
has_part GO:0005488
GO:0005041 : low-density lipoprotein receptor activity
is_a
GO:0030169
relationship
has_part GO:0030169
GO:0005047 : signal recognition particle binding
xref
Reactome:REACT_103640 "Interaction between SRP and SRP Receptor, Saccharomyces cerevisiae"
Reactome:REACT_30696 "Interaction between SRP and SRP Receptor, Bos taurus"
xref
Reactome:REACT_28177 "Interaction between SRP and SRP Receptor, Saccharomyces cerevisiae"
Reactome:REACT_94115 "Interaction between SRP and SRP Receptor, Bos taurus"
GO:0005048 : signal sequence binding
xref
Reactome:REACT_112627 "Signal Recognition (Preproinsulin), Rattus norvegicus"
Reactome:REACT_112794 "Signal Recognition (Preproinsulin), Bos taurus"
Reactome:REACT_113110 "Signal Recognition (Preproinsulin), Gallus gallus"
Reactome:REACT_113489 "Signal Recognition (Preprolactin), Gallus gallus"
Reactome:REACT_113823 "Signal Recognition (Preprolactin), Bos taurus"
Reactome:REACT_115380 "Signal Recognition (Preprolactin), Rattus norvegicus"
GO:0005049 : nuclear export signal receptor activity
def
Combining with a nuclear export signal to initiate a change in cell activity.
is_a
GO:0005515
def
Combining with a nuclear export signal (NES) to mediate transport of the NES-containing protein through the nuclear pore to the cytoplasm.
is_a
GO:0008565
relationship
part_of GO:0006611
GO:0005085 : guanyl-nucleotide exchange factor activity
xref
Reactome:REACT_100221 "Regeneration of eEF1A:GTP by eEF1B activity, Arabidopsis thaliana"
Reactome:REACT_100888 "Gq activation by TP receptor, Drosophila melanogaster"
Reactome:REACT_101345 "Regeneration of eEF1A:GTP by eEF1B activity, Oryza sativa"
Reactome:REACT_102212 "Activation of Gq by Muscarinic Acetylcholine Receptor M3, Drosophila melanogaster"
Reactome:REACT_109172 "C3G stimulates nucleotide exchange on Rap1, Sus scrofa"
Reactome:REACT_109777 "Liganded G12/13-activating GPCR acts as a GEF for G12/13, Caenorhabditis elegans"
Reactome:REACT_110192 "Gs activation by prostacyclin receptor, Drosophila melanogaster"
Reactome:REACT_110552 "Regeneration of eEF1A:GTP by eEF1B activity, Saccharomyces cerevisiae"
Reactome:REACT_110899 "Regeneration of eEF1A:GTP by eEF1B activity, Schizosaccharomyces pombe"
Reactome:REACT_28165 "Activation of Rap1 by membrane-associated GEFs, Dictyostelium discoideum"
Reactome:REACT_33310 "Liganded Gz-activating GPCR acts as a GEF for Gz, Drosophila melanogaster"
Reactome:REACT_34343 "Liganded Gi-activating GPCR acts as a GEF for Gi, Caenorhabditis elegans"
Reactome:REACT_79051 "G13 activation by TP receptor, Drosophila melanogaster"
Reactome:REACT_80201 "p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor, Arabidopsis thaliana"
Reactome:REACT_80698 "Regeneration of eEF1A:GTP by eEF1B activity, Caenorhabditis elegans"
Reactome:REACT_83698 "Liganded Gz-activating GPCR acts as a GEF for Gz, Caenorhabditis elegans"
Reactome:REACT_85329 "VAV3 is a GEF for Rho/Rac family kinases, Taeniopygia guttata"
Reactome:REACT_87231 "Liganded Gz-activating GPCR acts as a GEF for Gz, Sus scrofa"
Reactome:REACT_87937 "Liganded G12/13-activating GPCR acts as a GEF for G12/13, Sus scrofa"
Reactome:REACT_88096 "Activation of Gq by Muscarinic Acetylcholine Receptor M3, Caenorhabditis elegans"
Reactome:REACT_90940 "VAV3 is a GEF for Rho/Rac family kinases, Xenopus tropicalis"
Reactome:REACT_92764 "Liganded G12/13-activating GPCR acts as a GEF for G12/13, Drosophila melanogaster"
Reactome:REACT_95317 "Activation of Rap1 by membrane-associated GEFs, Sus scrofa"
Reactome:REACT_95747 "p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor, Oryza sativa"
Reactome:REACT_97664 "Liganded Gq/11-activating GPCRs act as GEFs for Gq/11, Bos taurus"
Reactome:REACT_98554 "Regeneration of eEF1A:GTP by eEF1B activity, Dictyostelium discoideum"
Reactome:REACT_99828 "Sar1p Activation And Membrane Binding, Caenorhabditis elegans"
xref
Reactome:REACT_101114 "Activation of Rap1 by membrane-associated GEFs, Sus scrofa"
Reactome:REACT_111195 "Activation of RAC1, Homo sapiens"
Reactome:REACT_112168 "Activation of Gq by Muscarinic Acetylcholine Receptor M3, Danio rerio"
Reactome:REACT_112243 "Activation of RAC1, Xenopus tropicalis"
Reactome:REACT_112276 "VAV2 is a GEF for Rho/Rac family kinases, Schizosaccharomyces pombe"
Reactome:REACT_112354 "Activation of RAC1, Mus musculus"
Reactome:REACT_112768 "Activation of RAC1, Bos taurus"
Reactome:REACT_113007 "Activation of RAC1, Canis familiaris"
Reactome:REACT_113090 "p115-RhoGEF activation of Rac1, Caenorhabditis elegans"
Reactome:REACT_113408 "VAV2 is a GEF for Rho/Rac family kinases, Saccharomyces cerevisiae"
Reactome:REACT_113526 "Activation of Rap1 by membrane-associated GEFs, Drosophila melanogaster"
Reactome:REACT_113541 "p115-RhoGEF activation of Rac1, Xenopus tropicalis"
Reactome:REACT_113598 "p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor, Dictyostelium discoideum"
Reactome:REACT_114659 "Activation of Gq by Fatty Acid Receptor 1: Fatty Acid Complex, Danio rerio"
Reactome:REACT_114904 "VAV3 is a GEF for Rho/Rac family kinases, Saccharomyces cerevisiae"
Reactome:REACT_115094 "VAV1 is a GEF for Rho/Rac family kinases, Caenorhabditis elegans"
Reactome:REACT_115111 "VAV3 is a GEF for Rho/Rac family kinases, Schizosaccharomyces pombe"
Reactome:REACT_115210 "Activation of RAC1, Drosophila melanogaster"
Reactome:REACT_29380 "Liganded G12/13-activating GPCR acts as a GEF for G12/13, Sus scrofa"
Reactome:REACT_90952 "Liganded Gz-activating GPCR acts as a GEF for Gz, Sus scrofa"
Reactome:REACT_92743 "Liganded Gq/11-activating GPCRs act as GEFs for Gq/11, Bos taurus"
GO:0005086 : ARF guanyl-nucleotide exchange factor activity
xref
Reactome:REACT_30645 "Arf1 Activation by GBF1, Schizosaccharomyces pombe"
Reactome:REACT_64759 "trans-Golgi Network Coat Activation, Saccharomyces cerevisiae"
Reactome:REACT_83517 "Arf1 Activation by GBF1, Saccharomyces cerevisiae"
xref
Reactome:REACT_90928 "Arf1 Activation by GBF1, Schizosaccharomyces pombe"
GO:0005088 : Ras guanyl-nucleotide exchange factor activity
xref
Reactome:REACT_100714 "Sos-mediated nucleotide exchange of Ras (PDGF receptor:Grb2:Sos), Drosophila melanogaster"
Reactome:REACT_101653 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2), Bos taurus"
Reactome:REACT_102004 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2), Danio rerio"
Reactome:REACT_102156 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2), Rattus norvegicus"
Reactome:REACT_102522 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2:Shc), Gallus gallus"
Reactome:REACT_103870 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2:Shc), Rattus norvegicus"
Reactome:REACT_106236 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2:Shc), Taeniopygia guttata"
Reactome:REACT_12386 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2), Homo sapiens"
Reactome:REACT_12402 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2:Shc), Homo sapiens"
Reactome:REACT_77034 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2), Gallus gallus"
Reactome:REACT_77575 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2:Shc), Mus musculus"
Reactome:REACT_79439 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2:Shc), Bos taurus"
Reactome:REACT_87691 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2), Xenopus tropicalis"
Reactome:REACT_88657 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2), Canis familiaris"
Reactome:REACT_88810 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2), Mus musculus"
Reactome:REACT_93477 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2), Taeniopygia guttata"
Reactome:REACT_96781 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2:Shc), Canis familiaris"
Reactome:REACT_98264 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2:Shc), Danio rerio"
Reactome:REACT_98780 "Sos-mediated nucleotide exchange of Ras (EGF:EGFR-Sos:Grb2:Shc), Xenopus tropicalis"
xref
Reactome:REACT_101653 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1), Bos taurus"
Reactome:REACT_102004 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1), Danio rerio"
Reactome:REACT_102156 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1), Rattus norvegicus"
Reactome:REACT_102522 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1), Gallus gallus"
Reactome:REACT_103870 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1), Rattus norvegicus"
Reactome:REACT_106236 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1), Taeniopygia guttata"
Reactome:REACT_111091 "Activation of RAS by p-KIT bound SOS1, Homo sapiens"
Reactome:REACT_111095 "Ras nucleotide exchange by GRB2:SOS1 through p-SHC, Homo sapiens"
Reactome:REACT_111126 "Ras nucleotide exchange by GRB2:SOS1 bound to p-FRS2:activated FGFR, Homo sapiens"
Reactome:REACT_12386 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1), Homo sapiens"
Reactome:REACT_12402 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1), Homo sapiens"
Reactome:REACT_77034 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1), Gallus gallus"
Reactome:REACT_77575 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1), Mus musculus"
Reactome:REACT_79439 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1), Bos taurus"
Reactome:REACT_87691 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1), Xenopus tropicalis"
Reactome:REACT_88657 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1), Canis familiaris"
Reactome:REACT_88810 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1), Mus musculus"
Reactome:REACT_93477 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1), Taeniopygia guttata"
Reactome:REACT_96781 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1), Canis familiaris"
Reactome:REACT_98264 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1), Danio rerio"
Reactome:REACT_98780 "SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1), Xenopus tropicalis"
GO:0005089 : Rho guanyl-nucleotide exchange factor activity
xref
Reactome:REACT_32109 "Activation of Rac1, Taeniopygia guttata"
Reactome:REACT_88977 "Activation of Cdc42, Taeniopygia guttata"
Reactome:REACT_90495 "Activation of Cdc42, Sus scrofa"
xref
Reactome:REACT_112014 "RhoA is activated by nucleotide exchange and inhibits axonal growth, Danio rerio"
Reactome:REACT_114452 "RhoA is activated by nucleotide exchange and inhibits axonal growth, Xenopus tropicalis"
Reactome:REACT_114487 "RhoA is activated by nucleotide exchange and inhibits axonal growth, Rattus norvegicus"
Reactome:REACT_96181 "Activation of Cdc42, Sus scrofa"
GO:0005096 : GTPase activator activity
xref
Reactome:REACT_104681 "TSC2 activates intrinsic GTPase activity of Rheb, Bos taurus"
Reactome:REACT_79656 "GAPs inactivate Rho GTPase:GTP by hydrolysis, Schizosaccharomyces pombe"
Reactome:REACT_86672 "Hydrolysis of Arf1-GTP to Arf1-GDP, Oryza sativa"
Reactome:REACT_88349 "Hydrolysis of Arf1-GTP to Arf1-GDP, Dictyostelium discoideum"
xref
Reactome:REACT_105205 "TSC2 activates intrinsic GTPase activity of Rheb, Bos taurus"
Reactome:REACT_112033 "Hydrolysis of Arf1-GTP to Arf1-GDP, Saccharomyces cerevisiae"
Reactome:REACT_115083 "Inactivation of R-Ras by Sema3A-Plexin-A GAP activity, Xenopus tropicalis"
Reactome:REACT_115497 "Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity, Xenopus tropicalis"
Reactome:REACT_29936 "GAPs inactivate Rho GTPase:GTP by hydrolysis, Schizosaccharomyces pombe"
Reactome:REACT_85789 "Hydrolysis of Arf1-GTP to Arf1-GDP, Dictyostelium discoideum"
GO:0005100 : Rho GTPase activator activity
xref
Reactome:REACT_114368 "Inactivation of Rho-GTP by p190RhoGAP, Danio rerio"
Reactome:REACT_115214 "Inactivation of Rho-GTP by p190RhoGAP, Rattus norvegicus"
GO:0005160 : transforming growth factor beta receptor binding
xref
Reactome:REACT_99071 "BMP2 binds to the receptor complex, Sus scrofa"
xref
Reactome:REACT_105409 "BMP2 binds to the receptor complex, Sus scrofa"
GO:0005231 : excitatory extracellular ligand-gated ion channel activity
xref
Reactome:REACT_112215 "Activation of Ca permeable AMPA receptors, Caenorhabditis elegans"
Reactome:REACT_112384 "Membrane depolarization upon activation of Ca impermeable AMPA receptors, Caenorhabditis elegans"
Reactome:REACT_112847 "Unblocking of NMDA receptor, Caenorhabditis elegans"
Reactome:REACT_112878 "Membrane depolarization upon activation of Ca impermeable AMPA receptors, Xenopus tropicalis"
Reactome:REACT_113112 "Unblocking of NMDA receptor, Xenopus tropicalis"
Reactome:REACT_113296 "Activation of Ca impermeable AMPA receptors, Xenopus tropicalis"
Reactome:REACT_115321 "Activation of Ca permeable AMPA receptors, Caenorhabditis elegans"
Reactome:REACT_115442 "Activation of Ca impermeable AMPA receptors, Caenorhabditis elegans"
GO:0005242 : inward rectifier potassium channel activity
xref
Reactome:REACT_75911 "Activation of ATP sensitive Potassium channels, Homo sapiens"
xref
Reactome:REACT_111144 "Activation of ATP sensitive Potassium channels in muscle cells, Homo sapiens"
Reactome:REACT_75911 "Activation of ATP sensitive Potassium channels in neuroendocrine cells, Homo sapiens"
GO:0005243 : gap junction channel activity
xref
Reactome:REACT_94968 "Connexin 62 mediated neuronal gap junction communication, Danio rerio"
xref
Reactome:REACT_112884 "Connexin 62 mediated neuronal gap junction communication, Xenopus tropicalis"
Reactome:REACT_115511 "Pannexin 1/Pannexin2 mediated neuronal gap junction communication, Xenopus tropicalis"
GO:0005253 : anion channel activity
xref
Reactome:REACT_102125 "Passive Transport of Anions into Vesicles by Aquaporin-6, Arabidopsis thaliana"
Reactome:REACT_33152 "Passive Transport of Anions out of Vesicles by Aquaporin-6, Arabidopsis thaliana"
Reactome:REACT_79379 "Passive Transport of Anions out of Vesicles by Aquaporin-6, Oryza sativa"
Reactome:REACT_82075 "Passive Transport of Anions into Vesicles by Aquaporin-6, Oryza sativa"
xref
Reactome:REACT_112326 "Passive Transport of Anions out of Vesicles by Aquaporin-6, Drosophila melanogaster"
Reactome:REACT_115452 "Passive Transport of Anions into Vesicles by Aquaporin-6, Drosophila melanogaster"
Reactome:REACT_115461 "Passive Transport of Anions into Vesicles by Aquaporin-6, Escherichia coli"
GO:0005254 : chloride channel activity
xref
Reactome:REACT_78973 "Group 3 - Selective Cl- transport, Caenorhabditis elegans"
Reactome:REACT_83769 "Group 3 - Selective Cl- transport, Drosophila melanogaster"
xref
Reactome:REACT_112123 "Group 3 - Selective Cl- transport, Plasmodium falciparum"
Reactome:REACT_114749 "Group 3 - Selective Cl- transport, Dictyostelium discoideum"
GO:0005261 : cation channel activity
xref
Reactome:REACT_112207 "Release of calcium from intracellular stores by IP3 receptor activation, Caenorhabditis elegans"
GO:0005262 : calcium channel activity
xref
Reactome:REACT_92531 "Ca2+ influx through voltage gated Ca2+ channels, Gallus gallus"
xref
Reactome:REACT_112515 "P2X1-mediated entry of Ca++ from plasma, Xenopus tropicalis"
Reactome:REACT_112676 "Transport of Ca++ from platelet dense tubular system to cytoplasm, Caenorhabditis elegans"
Reactome:REACT_114130 "Ca2+ influx through voltage gated Ca2+ channels, Xenopus tropicalis"
GO:0005276 : vesicular hydrogen:amino acid antiporter activity
xref
Reactome:REACT_112465 "Vesicular inhibitory amino acid transport, Saccharomyces cerevisiae"
Reactome:REACT_113824 "Vesicular inhibitory amino acid transport, Dictyostelium discoideum"
Reactome:REACT_114586 "Vesicular inhibitory amino acid transport, Arabidopsis thaliana"
Reactome:REACT_114587 "Vesicular inhibitory amino acid transport, Oryza sativa"
GO:0005277 : acetylcholine transmembrane transporter activity
xref
Reactome:REACT_112785 "Loading of acetylcholine in synaptic vesicle, Drosophila melanogaster"
Reactome:REACT_113105 "Loading of acetylcholine in synaptic vesicle, Xenopus tropicalis"
Reactome:REACT_114068 "Loading of acetylcholine in synaptic vesicle, Gallus gallus"
GO:0005309 : creatine:sodium symporter activity
xref
Reactome:REACT_112702 "Creatine transport across the plasma membrane, Gallus gallus"
Reactome:REACT_113563 "Creatine transport across the plasma membrane, Taeniopygia guttata"
Reactome:REACT_115072 "Creatine transport across the plasma membrane, Staphylococcus aureus N315"
Reactome:REACT_115159 "Creatine transport across the plasma membrane, Sus scrofa"
GO:0005310 : dicarboxylic acid transmembrane transporter activity
xref
Reactome:REACT_92805 "malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix], Bos taurus"
xref
Reactome:REACT_112858 "malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix], Oryza sativa"
Reactome:REACT_113407 "malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix], Drosophila melanogaster"
Reactome:REACT_113778 "malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix], Arabidopsis thaliana"
Reactome:REACT_90846 "malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix], Bos taurus"
GO:0005313 : L-glutamate transmembrane transporter activity
xref
Reactome:REACT_97115 "Vesicular glutamate transport, Dictyostelium discoideum"
xref
Reactome:REACT_112266 "Vesicular glutamate transport, Staphylococcus aureus N315"
Reactome:REACT_112417 "Vesicular glutamate transport, Arabidopsis thaliana"
Reactome:REACT_113125 "Vesicular glutamate transport, Oryza sativa"
Reactome:REACT_113198 "Vesicular glutamate transport, Escherichia coli"
Reactome:REACT_114619 "L-Glutamate loading of synaptic vesicle, Drosophila melanogaster"
Reactome:REACT_115281 "L-Glutamate loading of synaptic vesicle, Caenorhabditis elegans"
GO:0005314 : high-affinity glutamate transmembrane transporter activity
xref
Reactome:REACT_112875 "Glutamate transport, Drosophila melanogaster"
Reactome:REACT_114169 "Glutamate transport, Staphylococcus aureus N315"
GO:0005319 : lipid transporter activity
xref
Reactome:REACT_101503 "ABCA6, 10 and 12 in macrophage lipid homeostasis, Bos taurus"
Reactome:REACT_15303 "ABCA6, 10 and 12 in macrophage lipid homeostasis, Homo sapiens"
Reactome:REACT_77602 "ABCA6, 10 and 12 in macrophage lipid homeostasis, Taeniopygia guttata"
Reactome:REACT_97936 "ABCA6, 10 and 12 in macrophage lipid homeostasis, Gallus gallus"
xref
Reactome:REACT_111067 "ABCAs mediate lipid efflux, Homo sapiens"
Reactome:REACT_111169 "ABCAs mediate lipid influx, Homo sapiens"
Reactome:REACT_111998 "ABCAs mediate lipid efflux, Xenopus tropicalis"
Reactome:REACT_112083 "ABCAs mediate lipid efflux, Mycobacterium tuberculosis"
Reactome:REACT_112225 "ABCAs mediate lipid influx, Xenopus tropicalis"
Reactome:REACT_112273 "ABCAs mediate lipid influx, Canis familiaris"
Reactome:REACT_112420 "ABCAs mediate lipid efflux, Sus scrofa"
Reactome:REACT_112734 "ABCAs mediate lipid influx, Mus musculus"
Reactome:REACT_112793 "ABCAs mediate lipid influx, Drosophila melanogaster"
Reactome:REACT_112990 "ABCAs mediate lipid efflux, Drosophila melanogaster"
Reactome:REACT_113370 "ABCAs mediate lipid influx, Mycobacterium tuberculosis"
Reactome:REACT_113696 "ABCAs mediate lipid influx, Taeniopygia guttata"
Reactome:REACT_113865 "ABCAs mediate lipid influx, Danio rerio"
Reactome:REACT_113910 "ABCAs mediate lipid efflux, Canis familiaris"
Reactome:REACT_114060 "ABCAs mediate lipid efflux, Bos taurus"
Reactome:REACT_114336 "ABCAs mediate lipid efflux, Danio rerio"
Reactome:REACT_114700 "ABCAs mediate lipid efflux, Mus musculus"
Reactome:REACT_114808 "ABCAs mediate lipid efflux, Rattus norvegicus"
Reactome:REACT_114875 "ABCAs mediate lipid influx, Rattus norvegicus"
Reactome:REACT_114929 "ABCAs mediate lipid influx, Bos taurus"
Reactome:REACT_115011 "ABCAs mediate lipid influx, Sus scrofa"
Reactome:REACT_115076 "ABCAs mediate lipid influx, Gallus gallus"
Reactome:REACT_115091 "ABCAs mediate lipid efflux, Gallus gallus"
Reactome:REACT_115251 "ABCAs mediate lipid efflux, Taeniopygia guttata"
GO:0005324 : long-chain fatty acid transporter activity
xref
Reactome:REACT_101477 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Drosophila melanogaster"
Reactome:REACT_101752 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Saccharomyces cerevisiae"
Reactome:REACT_105421 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Dictyostelium discoideum"
Reactome:REACT_106740 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Mus musculus"
Reactome:REACT_15322 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Homo sapiens"
Reactome:REACT_29426 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Taeniopygia guttata"
Reactome:REACT_34095 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Caenorhabditis elegans"
Reactome:REACT_34135 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Danio rerio"
Reactome:REACT_34416 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Bos taurus"
Reactome:REACT_59791 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Sus scrofa"
Reactome:REACT_78591 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Canis familiaris"
Reactome:REACT_85267 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Gallus gallus"
Reactome:REACT_86284 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Xenopus tropicalis"
Reactome:REACT_91468 "ABCD1/ABCD3 mediates long chain fatty acid transport in to peroxisomes, Rattus norvegicus"
xref
Reactome:REACT_101477 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Drosophila melanogaster"
Reactome:REACT_101752 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Saccharomyces cerevisiae"
Reactome:REACT_106740 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Mus musculus"
Reactome:REACT_112344 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Escherichia coli"
Reactome:REACT_113806 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Mycobacterium tuberculosis"
Reactome:REACT_15322 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Homo sapiens"
Reactome:REACT_29426 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Taeniopygia guttata"
Reactome:REACT_34095 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Caenorhabditis elegans"
Reactome:REACT_34135 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Danio rerio"
Reactome:REACT_34416 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Bos taurus"
Reactome:REACT_59791 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Sus scrofa"
Reactome:REACT_78591 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Canis familiaris"
Reactome:REACT_85267 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Gallus gallus"
Reactome:REACT_86284 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Xenopus tropicalis"
Reactome:REACT_91468 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Rattus norvegicus"
Reactome:REACT_95170 "ABCD1/D2/D3 mediate long chain fatty acid transport in to peroxisomes, Dictyostelium discoideum"
GO:0005325 : peroxisomal fatty-acyl-CoA transporter activity
xref
Reactome:REACT_33050 "Peroxisomal uptake of very long-chain fatty acyl CoA, Taeniopygia guttata"
xref
Reactome:REACT_112629 "Peroxisomal uptake of very long-chain fatty acyl CoA, Escherichia coli"
Reactome:REACT_113055 "Peroxisomal uptake of very long-chain fatty acyl CoA, Mycobacterium tuberculosis"
GO:0005326 : neurotransmitter transporter activity
xref
Reactome:REACT_29685 "Uptake of Noradrenaline, Drosophila melanogaster"
xref
Reactome:REACT_112831 "Uptake of Noradrenaline, Xenopus tropicalis"
Reactome:REACT_114411 "Uptake of Noradrenaline, Danio rerio"
GO:0005337 : nucleoside transmembrane transporter activity
xref
Reactome:REACT_108665 "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1, Saccharomyces cerevisiae"
Reactome:REACT_77332 "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2, Saccharomyces cerevisiae"
Reactome:REACT_87112 "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1, Saccharomyces cerevisiae"
Reactome:REACT_98724 "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2, Saccharomyces cerevisiae"
xref
Reactome:REACT_104920 "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1, Saccharomyces cerevisiae"
Reactome:REACT_112137 "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2, Dictyostelium discoideum"
Reactome:REACT_112369 "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1, Dictyostelium discoideum"
Reactome:REACT_112717 "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1, Dictyostelium discoideum"
Reactome:REACT_112837 "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1, Drosophila melanogaster"
Reactome:REACT_113428 "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2, Dictyostelium discoideum"
Reactome:REACT_113840 "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2, Drosophila melanogaster"
Reactome:REACT_114976 "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2, Drosophila melanogaster"
Reactome:REACT_115150 "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1, Drosophila melanogaster"
Reactome:REACT_81421 "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2, Saccharomyces cerevisiae"
Reactome:REACT_87106 "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1, Saccharomyces cerevisiae"
Reactome:REACT_94316 "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2, Saccharomyces cerevisiae"
GO:0005353 : fructose transmembrane transporter activity
xref
Reactome:REACT_80040 "Transport (influx) of fructose by GLUT5, Drosophila melanogaster"
xref
Reactome:REACT_112097 "Transport (influx) of fructose by GLUT5, Mycobacterium tuberculosis"
Reactome:REACT_113496 "Transport (influx) of fructose by GLUT5, Dictyostelium discoideum"
Reactome:REACT_113519 "Transport (influx) of fructose by GLUT5, Oryza sativa"
Reactome:REACT_114250 "Transport (influx) of fructose by GLUT5, Plasmodium falciparum"
Reactome:REACT_114334 "Transport (influx) of fructose by GLUT5, Arabidopsis thaliana"
GO:0005355 : glucose transmembrane transporter activity
xref
Reactome:REACT_112687 "alpha-D-glucose (extracellular) <=> alpha-D-glucose (cytosol), Oryza sativa"
Reactome:REACT_113469 "alpha-D-glucose (extracellular) <=> alpha-D-glucose (cytosol), Dictyostelium discoideum"
Reactome:REACT_114420 "alpha-D-glucose (extracellular) <=> alpha-D-glucose (cytosol), Plasmodium falciparum"
Reactome:REACT_114521 "alpha-D-glucose (extracellular) <=> alpha-D-glucose (cytosol), Caenorhabditis elegans"
Reactome:REACT_114545 "alpha-D-glucose (extracellular) <=> alpha-D-glucose (cytosol), Drosophila melanogaster"
Reactome:REACT_114814 "alpha-D-glucose (extracellular) <=> alpha-D-glucose (cytosol), Arabidopsis thaliana"
Reactome:REACT_114865 "alpha-D-glucose (extracellular) <=> alpha-D-glucose (cytosol), Mycobacterium tuberculosis"
GO:0005366 : myo-inositol:hydrogen symporter activity
xref
Reactome:REACT_98349 "HMIT co-transports myo-inositol with a proton, Sus scrofa"
xref
Reactome:REACT_113525 "HMIT co-transports myo-inositol with a proton, Dictyostelium discoideum"
Reactome:REACT_114462 "HMIT co-transports myo-inositol with a proton, Gallus gallus"
Reactome:REACT_84498 "HMIT co-transports myo-inositol with a proton, Sus scrofa"
GO:0005375 : copper ion transmembrane transporter activity
xref
Reactome:REACT_101681 "Cellular copper transport is mediated by human copper transporter 1 hCTR1, Saccharomyces cerevisiae"
Reactome:REACT_107013 "Cellular copper transport is mediated by human copper transporter 1 hCTR1, Caenorhabditis elegans"
Reactome:REACT_29863 "Cellular copper transport is mediated by human copper transporter 1 hCTR1, Schizosaccharomyces pombe"
Reactome:REACT_31800 "Cellular copper transport is mediated by human copper transporter 1 hCTR1, Drosophila melanogaster"
Reactome:REACT_99232 "Cellular copper transport is mediated by human copper transporter 1 hCTR1, Dictyostelium discoideum"
xref
Reactome:REACT_82127 "Cellular copper transport is mediated by human copper transporter 1 hCTR1, Dictyostelium discoideum"
GO:0005381 : iron ion transmembrane transporter activity
xref
Reactome:REACT_113775 "DCT1 (NRAMP2) mediates divalent iron uptake across the apical membrane of enterocytes, Staphylococcus aureus N315"
GO:0005385 : zinc ion transmembrane transporter activity
xref
Reactome:REACT_74679 "ZnT1 mediates the efflux of zinc from the cell, Dictyostelium discoideum"
Reactome:REACT_86184 "ZnT1 mediates the efflux of zinc from the cell, Caenorhabditis elegans"
xref
Reactome:REACT_113068 "ZnT5 transports zinc into secretory granules in pancreatic beta cells, Arabidopsis thaliana"
Reactome:REACT_113230 "ZnT7 transports zinc into the golgi apparatus, Arabidopsis thaliana"
Reactome:REACT_113286 "ZnT7 transports zinc into the golgi apparatus, Oryza sativa"
Reactome:REACT_115265 "ZnT5 transports zinc into secretory granules in pancreatic beta cells, Oryza sativa"
Reactome:REACT_88379 "ZnT1 mediates the efflux of zinc from the cell, Dictyostelium discoideum"
GO:0005388 : calcium-transporting ATPase activity
xref
Reactome:REACT_28803 "PMCA extrusion of Ca2+, Saccharomyces cerevisiae"
Reactome:REACT_79077 "PMCA extrusion of Ca2+, Dictyostelium discoideum"
Reactome:REACT_92801 "PMCA extrusion of Ca2+, Schizosaccharomyces pombe"
GO:0005391 : sodium:potassium-exchanging ATPase activity
synonym
"na+/K+-exchanging ATPase activity" EXACT [EC:3.6.3.9]
GO:0005412 : glucose:sodium symporter activity
xref
Reactome:REACT_114364 "Co-transport (influx) of glucose and Na+ ions by SGLT2, Xenopus tropicalis"
GO:0005432 : calcium:sodium antiporter activity
xref
Reactome:REACT_113595 "Na+/Ca2+ exchanger transport, Drosophila melanogaster"
Reactome:REACT_115279 "Na+/Ca2+ exchanger transport, Caenorhabditis elegans"
GO:0005452 : inorganic anion exchanger activity
xref
Reactome:REACT_111979 "Cl-/HCO3- exchanger transport, Caenorhabditis elegans"
Reactome:REACT_112953 "Na+-driven Cl-/HCO3- exchanger transport, Dictyostelium discoideum"
Reactome:REACT_114173 "Cl-/HCO3- exchanger transport, Dictyostelium discoideum"
Reactome:REACT_114293 "Group 2 - Cl-/HCO3- exchanger transport, Dictyostelium discoideum"
Reactome:REACT_114573 "Group 2 - Cl-/HCO3- exchanger transport, Plasmodium falciparum"
GO:0005461 : UDP-glucuronic acid transmembrane transporter activity
xref
Reactome:REACT_113825 "UDP-glucuronate transport from the cytosol to ER lumen, Dictyostelium discoideum"
GO:0005487 : nucleocytoplasmic transporter activity
xref
Reactome:REACT_91299 "GCK1:GKRP [cytosol] => GCK1:GKRP [nucleoplasm], Canis familiaris"
xref
Reactome:REACT_114315 "GCK1:GKRP [cytosol] => GCK1:GKRP [nucleoplasm], Xenopus tropicalis"
GO:0005515 : protein binding
xref
Reactome:REACT_100108 "Formation of the IGF:IGFBP-5:ALS Complex, Bos taurus"
Reactome:REACT_102457 "An anchoring protein, SARA, recruits R-SMAD, Canis familiaris"
Reactome:REACT_104488 "Formation of the IGF:IGFBP-3:ALS Complex, Bos taurus"
Reactome:REACT_29941 "Formation of the IGF:IGFBP-4 Complex, Bos taurus"
Reactome:REACT_31648 "An anchoring protein, SARA, recruits R-SMAD, Mus musculus"
Reactome:REACT_33135 "An anchoring protein, SARA, recruits R-SMAD, Rattus norvegicus"
Reactome:REACT_6923 "An anchoring protein, SARA, recruits R-SMAD, Homo sapiens"
Reactome:REACT_77120 "Formation of the IGF:IGFBP-2 Complex, Bos taurus"
Reactome:REACT_85975 "An anchoring protein, SARA, recruits R-SMAD, Danio rerio"
Reactome:REACT_87187 "An anchoring protein, SARA, recruits R-SMAD, Xenopus tropicalis"
Reactome:REACT_90666 "An anchoring protein, SARA, recruits R-SMAD, Sus scrofa"
Reactome:REACT_93596 "Formation of the IGF:IGFBP-6 Complex, Bos taurus"
Reactome:REACT_98807 "An anchoring protein, SARA, recruits R-SMAD, Bos taurus"
xref
Reactome:REACT_102457 "An anchoring protein, SARA, recruits SMAD2/3, Canis familiaris"
Reactome:REACT_104029 "Formation of the IGF:IGFBP-6 Complex, Bos taurus"
Reactome:REACT_105895 "Formation of the IGF:IGFBP-4 Complex, Bos taurus"
Reactome:REACT_106168 "Formation of the IGF:IGFBP-2 Complex, Bos taurus"
Reactome:REACT_31648 "An anchoring protein, SARA, recruits SMAD2/3, Mus musculus"
Reactome:REACT_33135 "An anchoring protein, SARA, recruits SMAD2/3, Rattus norvegicus"
Reactome:REACT_6923 "An anchoring protein, SARA, recruits SMAD2/3, Homo sapiens"
Reactome:REACT_85975 "An anchoring protein, SARA, recruits SMAD2/3, Danio rerio"
Reactome:REACT_87187 "An anchoring protein, SARA, recruits SMAD2/3, Xenopus tropicalis"
Reactome:REACT_87652 "Formation of the IGF:IGFBP-5:ALS Complex, Bos taurus"
Reactome:REACT_90666 "An anchoring protein, SARA, recruits SMAD2/3, Sus scrofa"
Reactome:REACT_95647 "Formation of the IGF:IGFBP-3:ALS Complex, Bos taurus"
Reactome:REACT_98807 "An anchoring protein, SARA, recruits SMAD2/3, Bos taurus"
GO:0005524 : ATP binding
xref
Reactome:REACT_115254 "Closing of Inward Rectifying, ATP-sensitive Potassium Channels (KATP channels), Drosophila melanogaster"
GO:0005975 : carbohydrate metabolic process
xref
Reactome:REACT_101193 "Metabolism of carbohydrates, Sus scrofa"
xref
Reactome:REACT_90099 "Metabolism of carbohydrates, Sus scrofa"
GO:0005977 : glycogen metabolic process
def
The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha(1->4) glycosidic linkage, joined together by alpha(1->6) glycosidic linkages.
def
The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.
GO:0005978 : glycogen biosynthetic process
xref
Reactome:REACT_110962 "Glycogen synthesis, Staphylococcus aureus N315"
Reactome:REACT_89012 "Glycogen synthesis, Sus scrofa"
xref
Reactome:REACT_78900 "Glycogen synthesis, Sus scrofa"
GO:0005980 : glycogen catabolic process
xref
Reactome:REACT_107066 "Glycogen breakdown (glycogenolysis), Staphylococcus aureus N315"
Reactome:REACT_86564 "Glycogen breakdown (glycogenolysis), Dictyostelium discoideum"
Reactome:REACT_92711 "Glycogen breakdown (glycogenolysis), Sus scrofa"
xref
Reactome:REACT_79214 "Glycogen breakdown (glycogenolysis), Sus scrofa"
Reactome:REACT_88320 "Glycogen breakdown (glycogenolysis), Dictyostelium discoideum"
GO:0006001 : fructose catabolic process
xref
Reactome:REACT_33549 "Fructose catabolism, Sus scrofa"
xref
Reactome:REACT_94187 "Fructose catabolism, Sus scrofa"
GO:0006006 : glucose metabolic process
xref
Reactome:REACT_77853 "Glucose metabolism, Schizosaccharomyces pombe"
Reactome:REACT_88065 "Glucose metabolism, Sus scrofa"
xref
Reactome:REACT_30713 "Glucose metabolism, Schizosaccharomyces pombe"
Reactome:REACT_32548 "Glucose metabolism, Sus scrofa"
GO:0006015 : 5-phosphoribose 1-diphosphate biosynthetic process
xref
Reactome:REACT_100133 "5-Phosphoribose 1-diphosphate biosynthesis, Sus scrofa"
Reactome:REACT_107995 "5-Phosphoribose 1-diphosphate biosynthesis, Taeniopygia guttata"
xref
Reactome:REACT_105953 "5-Phosphoribose 1-diphosphate biosynthesis, Sus scrofa"
Reactome:REACT_113394 "5-Phosphoribose 1-diphosphate biosynthesis, Xenopus tropicalis"
GO:0006030 : chitin metabolic process
def
The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues.
def
The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.
GO:0006031 : chitin biosynthetic process
def
The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues.
def
The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.
GO:0006032 : chitin catabolic process
def
The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues.
def
The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.
GO:0006034 : cuticle chitin metabolic process
def
The chemical reactions and pathways involving cuticle chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in cuticles.
def
The chemical reactions and pathways involving cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles.
GO:0006035 : cuticle chitin biosynthetic process
def
The chemical reactions and pathways resulting in the formation of cuticle chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in cuticles.
def
The chemical reactions and pathways resulting in the formation of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles.
GO:0006036 : cuticle chitin catabolic process
def
The chemical reactions and pathways resulting in the breakdown of cuticle chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in cuticles.
def
The chemical reactions and pathways resulting in the breakdown of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles.
GO:0006037 : cell wall chitin metabolic process
def
The chemical reactions and pathways involving cell wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of cells.
def
The chemical reactions and pathways involving cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells.
GO:0006038 : cell wall chitin biosynthetic process
def
The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of cells.
def
The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells.
GO:0006039 : cell wall chitin catabolic process
def
The chemical reactions and pathways resulting in the breakdown of cell wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of cells.
def
The chemical reactions and pathways resulting in the breakdown of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells.
GO:0006065 : UDP-glucuronate biosynthetic process
xref
Reactome:REACT_86979 "Formation of the active cofactor, UDP-glucuronate, Sus scrofa"
xref
Reactome:REACT_107830 "Formation of the active cofactor, UDP-glucuronate, Sus scrofa"
Reactome:REACT_113773 "Formation of the active cofactor, UDP-glucuronate, Escherichia coli"
GO:0006069 : ethanol oxidation
xref
Reactome:REACT_78153 "Ethanol oxidation, Schizosaccharomyces pombe"
Reactome:REACT_86838 "Ethanol oxidation, Saccharomyces cerevisiae"
Reactome:REACT_92892 "Ethanol oxidation, Sus scrofa"
xref
Reactome:REACT_113258 "Ethanol oxidation, Dictyostelium discoideum"
Reactome:REACT_114164 "Ethanol oxidation, Escherichia coli"
Reactome:REACT_86318 "Ethanol oxidation, Sus scrofa"
GO:0006074 : (1->3)-beta-D-glucan metabolic process
name
1,3-beta-D-glucan metabolic process
def
The chemical reactions and pathways involving beta-1,3 glucans, compounds composed of glucose residues linked by 1,3-beta-D-glucosidic bonds.
synonym
"1,3-beta-glucan metabolism" EXACT []
name
(1->3)-beta-D-glucan metabolic process
def
The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds.
synonym
"1,3-beta-D-glucan metabolic process" BROAD [GOC:tb]
"1,3-beta-D-glucan metabolism" EXACT []
GO:0006075 : (1->3)-beta-D-glucan biosynthetic process
name
1,3-beta-D-glucan biosynthetic process
def
The chemical reactions and pathways resulting in the formation of beta-1,3 glucans, compounds composed of glucose residues linked by 1,3-beta-D-glucosidic bonds.
synonym
"1,3-beta-glucan biosynthetic process" BROAD [GOC:tb]
name
(1->3)-beta-D-glucan biosynthetic process
def
The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds.
synonym
"1,3-beta-D-glucan biosynthetic process" EXACT []
GO:0006076 : (1->3)-beta-D-glucan catabolic process
name
1,3-beta-D-glucan catabolic process
def
The chemical reactions and pathways resulting in the breakdown of beta-1,3 glucans.
synonym
"1,3-beta-glucan catabolic process" BROAD [GOC:tb]
name
(1->3)-beta-D-glucan catabolic process
def
The chemical reactions and pathways resulting in the breakdown of (1->3)-beta-D-glucans.
synonym
"1,3-beta-D-glucan catabolic process" EXACT []
GO:0006077 : (1->6)-beta-D-glucan metabolic process
name
1,6-beta-glucan metabolic process
def
The chemical reactions and pathways involving beta-1,6 glucans, compounds composed of glucose residues linked by 1,6-beta-D-glucosidic bonds.
name
(1->6)-beta-D-glucan metabolic process
def
The chemical reactions and pathways involving (1->6)-beta-D-glucans, compounds composed of glucose residues linked by (1->6)-beta-D-glucosidic bonds.
synonym
"1,6-beta-glucan metabolic process" EXACT []
GO:0006078 : (1->6)-beta-D-glucan biosynthetic process
name
1,6-beta-glucan biosynthetic process
def
The chemical reactions and pathways resulting in the formation of beta-1,6 glucans.
name
(1->6)-beta-D-glucan biosynthetic process
def
The chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans.
synonym
"1,6-beta-glucan biosynthetic process" EXACT []
GO:0006079 : (1->6)-beta-D-glucan catabolic process
name
1,6-beta-glucan catabolic process
def
The chemical reactions and pathways resulting in the breakdown of beta-1,6 glucans.
synonym
"1,6-beta-glucan breakdown" EXACT []
"1,6-beta-glucan catabolism" EXACT []
"1,6-beta-glucan degradation" EXACT []
name
(1->6)-beta-D-glucan catabolic process
def
The chemical reactions and pathways resulting in the breakdown of (1->6)-beta-D-glucans.
synonym
"1,6-beta-D-glucan breakdown" EXACT []
"1,6-beta-D-glucan catabolic process" EXACT []
"1,6-beta-D-glucan catabolism" EXACT []
"1,6-beta-D-glucan degradation" EXACT []
GO:0006090 : pyruvate metabolic process
xref
Reactome:REACT_30108 "Pyruvate metabolism, Plasmodium falciparum"
Reactome:REACT_98406 "Pyruvate metabolism, Sus scrofa"
xref
Reactome:REACT_101182 "Pyruvate metabolism, Sus scrofa"
Reactome:REACT_112876 "Pyruvate metabolism, Drosophila melanogaster"
GO:0006094 : gluconeogenesis
xref
Reactome:REACT_31854 "Gluconeogenesis, Sus scrofa"
xref
Reactome:REACT_78124 "Gluconeogenesis, Sus scrofa"
GO:0006096 : glycolysis
xref
Reactome:REACT_110298 "Glycolysis, Sus scrofa"
xref
Reactome:REACT_99995 "Glycolysis, Sus scrofa"
GO:0006098 : pentose-phosphate shunt
xref
Reactome:REACT_109960 "Pentose phosphate pathway (hexose monophosphate shunt), Sus scrofa"
xref
Reactome:REACT_81319 "Pentose phosphate pathway (hexose monophosphate shunt), Sus scrofa"
GO:0006099 : tricarboxylic acid cycle
xref
Reactome:REACT_83444 "Citric acid cycle (TCA cycle), Sus scrofa"
xref
Reactome:REACT_89038 "Citric acid cycle (TCA cycle), Sus scrofa"
GO:0006112 : energy reserve metabolic process
xref
Reactome:REACT_80630 "Integration of energy metabolism, Sus scrofa"
xref
Reactome:REACT_98844 "Integration of energy metabolism, Sus scrofa"
GO:0006121 : mitochondrial electron transport, succinate to ubiquinone
xref
Reactome:REACT_91586 "Transfer of electrons through the succinate dehydrogenase complex, Saccharomyces cerevisiae"
xref
Reactome:REACT_88562 "Transfer of electrons through the succinate dehydrogenase complex, Saccharomyces cerevisiae"
GO:0006122 : mitochondrial electron transport, ubiquinol to cytochrome c
xref
Reactome:REACT_112720 "Electron transfer from ubiquinol to cytochrome c of complex III, Canis familiaris"
Reactome:REACT_112947 "Electron transfer from ubiquinol to cytochrome c of complex III, Drosophila melanogaster"
Reactome:REACT_113468 "Electron transfer from ubiquinol to cytochrome c of complex III, Rattus norvegicus"
Reactome:REACT_113728 "Electron transfer from ubiquinol to cytochrome c of complex III, Bos taurus"
Reactome:REACT_115341 "Electron transfer from ubiquinol to cytochrome c of complex III, Sus scrofa"
GO:0006123 : mitochondrial electron transport, cytochrome c to oxygen
xref
Reactome:REACT_113276 "Electron transfer from reduced cytochrome c to molecular oxygen, Bos taurus"
Reactome:REACT_113311 "Electron transfer from reduced cytochrome c to molecular oxygen, Sus scrofa"
Reactome:REACT_113736 "Electron transfer from reduced cytochrome c to molecular oxygen, Canis familiaris"
Reactome:REACT_115027 "Electron transfer from reduced cytochrome c to molecular oxygen, Rattus norvegicus"
GO:0006144 : purine base metabolic process
xref
Reactome:REACT_77402 "Purine metabolism, Sus scrofa"
xref
Reactome:REACT_80519 "Purine metabolism, Sus scrofa"
GO:0006195 : purine nucleotide catabolic process
xref
Reactome:REACT_99545 "Purine catabolism, Sus scrofa"
xref
Reactome:REACT_113844 "Purine catabolism, Plasmodium falciparum"
Reactome:REACT_95337 "Purine catabolism, Sus scrofa"
GO:0006206 : pyrimidine base metabolic process
xref
Reactome:REACT_32378 "Pyrimidine metabolism, Schizosaccharomyces pombe"
Reactome:REACT_78271 "Pyrimidine metabolism, Sus scrofa"
xref
Reactome:REACT_30436 "Pyrimidine metabolism, Schizosaccharomyces pombe"
Reactome:REACT_33296 "Pyrimidine metabolism, Sus scrofa"
GO:0006260 : DNA replication
xref
Reactome:REACT_85266 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Dictyostelium discoideum"
xref
Reactome:REACT_112472 "Activation of ATR in response to replication stress, Saccharomyces cerevisiae"
Reactome:REACT_113703 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Gallus gallus"
Reactome:REACT_33572 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Dictyostelium discoideum"
GO:0006270 : DNA-dependent DNA replication initiation
xref
Reactome:REACT_85264 "DNA replication initiation, Sus scrofa"
xref
Reactome:REACT_77017 "DNA replication initiation, Sus scrofa"
GO:0006271 : DNA strand elongation involved in DNA replication
xref
Reactome:REACT_88412 "DNA strand elongation, Sus scrofa"
xref
Reactome:REACT_95055 "DNA strand elongation, Sus scrofa"
GO:0006281 : DNA repair
xref
Reactome:REACT_33728 "DNA Damage Reversal, Sus scrofa"
Reactome:REACT_34272 "DNA Repair, Dictyostelium discoideum"
Reactome:REACT_83599 "DNA Repair, Sus scrofa"
Reactome:REACT_89358 "DNA Damage Reversal, Escherichia coli"
xref
Reactome:REACT_94204 "DNA Repair, Sus scrofa"
Reactome:REACT_95050 "DNA Damage Reversal, Sus scrofa"
Reactome:REACT_96052 "DNA Repair, Dictyostelium discoideum"
GO:0006283 : transcription-coupled nucleotide-excision repair
xref
Reactome:REACT_109110 "Transcription-coupled NER (TC-NER), Dictyostelium discoideum"
xref
Reactome:REACT_81637 "Transcription-coupled NER (TC-NER), Dictyostelium discoideum"
GO:0006284 : base-excision repair
xref
Reactome:REACT_85616 "Base Excision Repair, Dictyostelium discoideum"
xref
Reactome:REACT_91955 "Base Excision Repair, Dictyostelium discoideum"
GO:0006286 : base-excision repair, base-free sugar-phosphate removal
xref
Reactome:REACT_86232 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Sus scrofa"
xref
Reactome:REACT_85754 "Excision of the abasic sugar phosphate (dRP) residue at the strand break, Sus scrofa"
GO:0006288 : base-excision repair, DNA ligation
xref
Reactome:REACT_80904 "Ligation of DNA at sites of patch replacement, Sus scrofa"
xref
Reactome:REACT_31800 "Ligation of DNA at sites of patch replacement, Sus scrofa"
GO:0006289 : nucleotide-excision repair
xref
Reactome:REACT_105090 "Nucleotide Excision Repair, Sus scrofa"
xref
Reactome:REACT_30685 "Nucleotide Excision Repair, Sus scrofa"
GO:0006293 : nucleotide-excision repair, preincision complex stabilization
xref
Reactome:REACT_96915 "Binding of ERCC1-XPF to preincision complex, Saccharomyces cerevisiae"
xref
Reactome:REACT_114006 "Binding of ERCC1-XPF to preincision complex, Caenorhabditis elegans"
Reactome:REACT_28578 "Binding of ERCC1-XPF to preincision complex, Saccharomyces cerevisiae"
GO:0006294 : nucleotide-excision repair, preincision complex assembly
xref
Reactome:REACT_107925 "Recruitment of repair factors to form preincision complex, Bos taurus"
xref
Reactome:REACT_112711 "Recruitment of repair factors to form preincision complex, Xenopus tropicalis"
GO:0006296 : nucleotide-excision repair, DNA incision, 5'-to lesion
xref
Reactome:REACT_91600 "5'-incision of DNA by ERCC1-XPF in GG-NER, Bos taurus"
xref
Reactome:REACT_112122 "5'-incision of DNA by ERCC1-XPF in GG-NER, Xenopus tropicalis"
GO:0006303 : double-strand break repair via nonhomologous end joining
xref
Reactome:REACT_114794 "Nonhomologous End-joining (NHEJ), Xenopus tropicalis"
GO:0006307 : DNA dealkylation involved in DNA repair
xref
Reactome:REACT_102469 "MGMT/hAGT mediated DNA Damage Reversal, Escherichia coli"
Reactome:REACT_87264 "MGMT/hAGT mediated DNA Damage Reversal, Sus scrofa"
xref
Reactome:REACT_108289 "MGMT/hAGT mediated DNA Damage Reversal, Sus scrofa"
Reactome:REACT_113126 "ABH2 mediated Reversal of Alkylation Damage, Oryza sativa"
Reactome:REACT_113979 "ABH2 mediated Reversal of Alkylation Damage, Arabidopsis thaliana"
GO:0006309 : DNA fragmentation involved in apoptotic nuclear change
xref
Reactome:REACT_113418 "Apoptosis induced DNA fragmentation, Plasmodium falciparum"
GO:0006360 : transcription from RNA polymerase I promoter
xref
Reactome:REACT_96840 "RNA Polymerase I Transcription, Sus scrofa"
xref
Reactome:REACT_77153 "RNA Polymerase I Transcription, Sus scrofa"
GO:0006361 : transcription initiation from RNA polymerase I promoter
xref
Reactome:REACT_106811 "RNA Polymerase I Transcription Initiation, Sus scrofa"
Reactome:REACT_109032 "RNA Polymerase I Promoter Opening, Sus scrofa"
Reactome:REACT_29994 "RNA Polymerase I Promoter Clearance, Dictyostelium discoideum"
Reactome:REACT_85489 "RNA Polymerase I Promoter Escape, Bos taurus"
Reactome:REACT_89661 "RNA Polymerase I Promoter Escape, Canis familiaris"
Reactome:REACT_96041 "RNA Polymerase I Promoter Clearance, Sus scrofa"
xref
Reactome:REACT_108556 "RNA Polymerase I Promoter Clearance, Dictyostelium discoideum"
Reactome:REACT_112001 "RNA Polymerase I Promoter Escape, Oryza sativa"
Reactome:REACT_112095 "RNA Polymerase I Promoter Opening, Rattus norvegicus"
Reactome:REACT_113247 "RNA Polymerase I Promoter Escape, Gallus gallus"
Reactome:REACT_114933 "RNA Polymerase I Promoter Escape, Rattus norvegicus"
Reactome:REACT_28247 "RNA Polymerase I Transcription Initiation, Sus scrofa"
Reactome:REACT_28672 "RNA Polymerase I Promoter Clearance, Sus scrofa"
Reactome:REACT_80295 "RNA Polymerase I Promoter Opening, Sus scrofa"
GO:0006362 : transcription elongation from RNA polymerase I promoter
xref
Reactome:REACT_112721 "RNA Polymerase I Chain Elongation, Oryza sativa"
Reactome:REACT_115044 "RNA Polymerase I Chain Elongation, Gallus gallus"
GO:0006363 : termination of RNA polymerase I transcription
xref
Reactome:REACT_113509 "RNA Polymerase I Transcription Termination, Gallus gallus"
GO:0006368 : transcription elongation from RNA polymerase II promoter
xref
Reactome:REACT_112408 "Formation of RNA Pol II elongation complex, Drosophila melanogaster"
Reactome:REACT_112630 "Formation of RNA Pol II elongation complex, Schizosaccharomyces pombe"
Reactome:REACT_113325 "Formation of RNA Pol II elongation complex, Caenorhabditis elegans"
Reactome:REACT_115524 "Formation of RNA Pol II elongation complex, Danio rerio"
GO:0006369 : termination of RNA polymerase II transcription
xref
Reactome:REACT_32387 "RNA Polymerase II Transcription Termination, Sus scrofa"
Reactome:REACT_81555 "Cleavage of Growing Transcript in the Termination Region, Sus scrofa"
xref
Reactome:REACT_112978 "RNA Polymerase II Transcription Termination, Drosophila melanogaster"
Reactome:REACT_113157 "RNA Polymerase II Transcription Termination, Arabidopsis thaliana"
Reactome:REACT_113171 "Cleavage of Growing Transcript in the Termination Region, Drosophila melanogaster"
Reactome:REACT_114593 "Cleavage of Growing Transcript in the Termination Region, Danio rerio"
Reactome:REACT_114998 "RNA Polymerase II Transcription Termination, Danio rerio"
Reactome:REACT_115466 "Cleavage of Growing Transcript in the Termination Region, Arabidopsis thaliana"
GO:0006370 : mRNA capping
xref
Reactome:REACT_87402 "mRNA Capping, Dictyostelium discoideum"
xref
Reactome:REACT_114999 "mRNA Capping, Plasmodium falciparum"
Reactome:REACT_96579 "mRNA Capping, Dictyostelium discoideum"
GO:0006382 : adenosine to inosine editing
xref
Reactome:REACT_112523 "mRNA Editing: A to I Conversion, Saccharomyces cerevisiae"
Reactome:REACT_112594 "mRNA Editing: A to I Conversion, Caenorhabditis elegans"
Reactome:REACT_112784 "mRNA Editing: A to I Conversion, Arabidopsis thaliana"
Reactome:REACT_112897 "mRNA Editing: A to I Conversion, Oryza sativa"
Reactome:REACT_113069 "mRNA Editing: A to I Conversion, Schizosaccharomyces pombe"
GO:0006383 : transcription from RNA polymerase III promoter
xref
Reactome:REACT_112623 "RNA Polymerase III Abortive Initiation At Type 3 Open Promoters, Drosophila melanogaster"
Reactome:REACT_112804 "RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters, Dictyostelium discoideum"
Reactome:REACT_113692 "RNA Polymerase III Abortive Initiation At Type 2 Open Promoters, Dictyostelium discoideum"
Reactome:REACT_114988 "RNA Polymerase III Simple Start Sequence Initiation At Type 3 Promoters, Drosophila melanogaster"
GO:0006397 : mRNA processing
xref
Reactome:REACT_113864 "Processing of Capped Intronless Pre-mRNA, Saccharomyces cerevisiae"
Reactome:REACT_114358 "Processing of Capped Intronless Pre-mRNA, Schizosaccharomyces pombe"
Reactome:REACT_115262 "Processing of Capped Intronless Pre-mRNA, Arabidopsis thaliana"
GO:0006405 : RNA export from nucleus
xref
Reactome:REACT_109623 "Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC, Drosophila melanogaster"
Reactome:REACT_28678 "Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC, Drosophila melanogaster"
Reactome:REACT_77395 "Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC, Drosophila melanogaster"
xref
Reactome:REACT_114184 "Recruitment of TAP to the EJC, Drosophila melanogaster"
GO:0006406 : mRNA export from nucleus
xref
Reactome:REACT_100049 "Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC, Drosophila melanogaster"
Reactome:REACT_102246 "Transport of the export-competent complex through the NPC, Xenopus tropicalis"
Reactome:REACT_109313 "Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex, Drosophila melanogaster"
Reactome:REACT_91579 "Release from the NPC and Disassembly of the mRNP, Drosophila melanogaster"
Reactome:REACT_92048 "Release of the SLBP independent Histone mRNA from the NPC, Drosophila melanogaster"
Reactome:REACT_96477 "Transport of Mature mRNAs Derived from Intronless Transcripts, Drosophila melanogaster"
xref
Reactome:REACT_112057 "Docking of Mature Replication Dependent Histone mRNA with the NPC, Danio rerio"
Reactome:REACT_113695 "Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC, Danio rerio"
Reactome:REACT_114603 "Docking of Mature Histone mRNA complex:TAP at the NPC, Danio rerio"
GO:0006412 : translation
xref
Reactome:REACT_84182 "Translation, Sus scrofa"
xref
Reactome:REACT_100338 "Translation, Sus scrofa"
GO:0006413 : translational initiation
xref
Reactome:REACT_101789 "Eukaryotic Translation Initiation, Gallus gallus"
Reactome:REACT_104290 "Eukaryotic Translation Initiation, Xenopus tropicalis"
Reactome:REACT_2159 "Eukaryotic Translation Initiation, Homo sapiens"
Reactome:REACT_29447 "Eukaryotic Translation Initiation, Dictyostelium discoideum"
Reactome:REACT_30389 "Eukaryotic Translation Initiation, Oryza sativa"
Reactome:REACT_33969 "Eukaryotic Translation Initiation, Caenorhabditis elegans"
Reactome:REACT_34354 "Eukaryotic Translation Initiation, Taeniopygia guttata"
Reactome:REACT_77252 "Eukaryotic Translation Initiation, Drosophila melanogaster"
Reactome:REACT_79705 "Eukaryotic Translation Initiation, Rattus norvegicus"
Reactome:REACT_85780 "Eukaryotic Translation Initiation, Bos taurus"
Reactome:REACT_88031 "Eukaryotic Translation Initiation, Schizosaccharomyces pombe"
Reactome:REACT_91066 "Eukaryotic Translation Initiation, Arabidopsis thaliana"
Reactome:REACT_95293 "Eukaryotic Translation Initiation, Plasmodium falciparum"
Reactome:REACT_95552 "Eukaryotic Translation Initiation, Mus musculus"
Reactome:REACT_95685 "Eukaryotic Translation Initiation, Canis familiaris"
Reactome:REACT_97707 "Eukaryotic Translation Initiation, Sus scrofa"
Reactome:REACT_98138 "Eukaryotic Translation Initiation, Saccharomyces cerevisiae"
Reactome:REACT_99004 "Eukaryotic Translation Initiation, Danio rerio"
GO:0006414 : translational elongation
xref
Reactome:REACT_109322 "Eukaryotic Translation Elongation, Sus scrofa"
Reactome:REACT_97803 "Eukaryotic Translation Elongation, Dictyostelium discoideum"
xref
Reactome:REACT_100207 "Eukaryotic Translation Elongation, Dictyostelium discoideum"
Reactome:REACT_31079 "Eukaryotic Translation Elongation, Sus scrofa"
GO:0006415 : translational termination
xref
Reactome:REACT_106717 "Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex, Dictyostelium discoideum"
xref
Reactome:REACT_112381 "GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex, Gallus gallus"
Reactome:REACT_112559 "GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex, Rattus norvegicus"
Reactome:REACT_112632 "Eukaryotic Translation Termination, Rattus norvegicus"
Reactome:REACT_113540 "GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex, Gallus gallus"
Reactome:REACT_114142 "Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex, Bos taurus"
Reactome:REACT_114287 "Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex, Gallus gallus"
Reactome:REACT_114807 "Eukaryotic Translation Termination, Gallus gallus"
Reactome:REACT_115292 "Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex, Rattus norvegicus"
Reactome:REACT_115309 "GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex, Bos taurus"
Reactome:REACT_115424 "Eukaryotic Translation Termination, Bos taurus"
Reactome:REACT_33545 "Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex, Dictyostelium discoideum"
GO:0006418 : tRNA aminoacylation for protein translation
xref
Reactome:REACT_104322 "Cytosolic tRNA aminoacylation, Sus scrofa"
Reactome:REACT_90554 "tRNA Aminoacylation, Sus scrofa"
xref
Reactome:REACT_100416 "Cytosolic tRNA aminoacylation, Sus scrofa"
Reactome:REACT_81425 "tRNA Aminoacylation, Sus scrofa"
GO:0006488 : dolichol-linked oligosaccharide biosynthetic process
xref
Reactome:REACT_79420 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein, Caenorhabditis elegans"
xref
Reactome:REACT_30432 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein, Caenorhabditis elegans"
GO:0006501 : C-terminal protein lipidation
xref
Reactome:REACT_87521 "Post-translational modification: synthesis of GPI-anchored proteins, Sus scrofa"
xref
Reactome:REACT_106946 "Post-translational modification: synthesis of GPI-anchored proteins, Sus scrofa"
GO:0006548 : histidine catabolic process
xref
Reactome:REACT_102083 "Histidine catabolism, Sus scrofa"
xref
Reactome:REACT_103575 "Histidine catabolism, Sus scrofa"
GO:0006554 : lysine catabolic process
xref
Reactome:REACT_100380 "Lysine catabolism, Sus scrofa"
xref
Reactome:REACT_113274 "Lysine catabolism, Escherichia coli"
Reactome:REACT_88111 "Lysine catabolism, Sus scrofa"
GO:0006559 : L-phenylalanine catabolic process
xref
Reactome:REACT_89997 "Phenylalanine and tyrosine catabolism, Sus scrofa"
xref
Reactome:REACT_98835 "Phenylalanine and tyrosine catabolism, Sus scrofa"
GO:0006569 : tryptophan catabolic process
xref
Reactome:REACT_103644 "Tryptophan catabolism, Sus scrofa"
xref
Reactome:REACT_76959 "Tryptophan catabolism, Sus scrofa"
GO:0006600 : creatine metabolic process
xref
Reactome:REACT_90153 "Creatine metabolism, Sus scrofa"
xref
Reactome:REACT_112303 "Creatine metabolism, Staphylococcus aureus N315"
Reactome:REACT_87835 "Creatine metabolism, Sus scrofa"
GO:0006629 : lipid metabolic process
xref
Reactome:REACT_98052 "Lipid digestion, mobilization, and transport, Caenorhabditis elegans"
xref
Reactome:REACT_114669 "Lipid digestion, mobilization, and transport, Staphylococcus aureus N315"
Reactome:REACT_87884 "Lipid digestion, mobilization, and transport, Caenorhabditis elegans"
GO:0006635 : fatty acid beta-oxidation
xref
Reactome:REACT_110665 "Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA, Mycobacterium tuberculosis"
Reactome:REACT_51199 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Bos taurus"
Reactome:REACT_76961 "Mitochondrial Fatty Acid Beta-Oxidation, Sus scrofa"
Reactome:REACT_82039 "dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA, Caenorhabditis elegans"
Reactome:REACT_88198 "Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA, Bos taurus"
xref
Reactome:REACT_113891 "Mitochondrial Fatty Acid Beta-Oxidation, Staphylococcus aureus N315"
Reactome:REACT_34789 "Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA, Bos taurus"
Reactome:REACT_81660 "Mitochondrial Fatty Acid Beta-Oxidation, Sus scrofa"
Reactome:REACT_99180 "dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA, Caenorhabditis elegans"
Reactome:REACT_99776 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Bos taurus"
GO:0006665 : sphingolipid metabolic process
xref
Reactome:REACT_112370 "Sphingolipid metabolism, Escherichia coli"
GO:0006692 : prostanoid metabolic process
xref
Reactome:REACT_113225 "Prostanoid metabolism, Mycobacterium tuberculosis"
GO:0006695 : cholesterol biosynthetic process
xref
Reactome:REACT_90089 "Cholesterol biosynthesis, Schizosaccharomyces pombe"
xref
Reactome:REACT_105508 "Cholesterol biosynthesis, Schizosaccharomyces pombe"
GO:0006699 : bile acid biosynthetic process
xref
Reactome:REACT_104896 "Synthesis of bile acids and bile salts via 27-hydroxycholesterol, Schizosaccharomyces pombe"
Reactome:REACT_31259 "Synthesis of bile acids and bile salts via 27-hydroxycholesterol, Caenorhabditis elegans"
Reactome:REACT_89285 "Synthesis of bile acids and bile salts via 24-hydroxycholesterol, Schizosaccharomyces pombe"
xref
Reactome:REACT_112535 "Synthesis of bile acids and bile salts via 24-hydroxycholesterol, Dictyostelium discoideum"
Reactome:REACT_113154 "Synthesis of bile acids and bile salts via 24-hydroxycholesterol, Oryza sativa"
Reactome:REACT_113534 "Synthesis of bile acids and bile salts via 27-hydroxycholesterol, Mycobacterium tuberculosis"
Reactome:REACT_113599 "Synthesis of bile acids and bile salts via 27-hydroxycholesterol, Oryza sativa"
Reactome:REACT_113889 "Synthesis of bile acids and bile salts, Plasmodium falciparum"
Reactome:REACT_114349 "Synthesis of bile acids and bile salts via 27-hydroxycholesterol, Arabidopsis thaliana"
Reactome:REACT_114625 "Synthesis of bile acids and bile salts via 27-hydroxycholesterol, Dictyostelium discoideum"
Reactome:REACT_114646 "Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol, Plasmodium falciparum"
GO:0006700 : C21-steroid hormone biosynthetic process
xref
Reactome:REACT_84578 "Pregnenolone biosynthesis, Escherichia coli"
Reactome:REACT_92167 "Pregnenolone biosynthesis, Schizosaccharomyces pombe"
xref
Reactome:REACT_113158 "Pregnenolone biosynthesis, Dictyostelium discoideum"
Reactome:REACT_115282 "Pregnenolone biosynthesis, Oryza sativa"
Reactome:REACT_115412 "Pregnenolone biosynthesis, Arabidopsis thaliana"
GO:0006702 : androgen biosynthetic process
xref
Reactome:REACT_104244 "Androgen biosynthesis, Caenorhabditis elegans"
Reactome:REACT_32608 "Androgen biosynthesis, Dictyostelium discoideum"
xref
Reactome:REACT_112163 "Androgen biosynthesis, Escherichia coli"
Reactome:REACT_112753 "Androgen biosynthesis, Mycobacterium tuberculosis"
Reactome:REACT_98944 "Androgen biosynthesis, Dictyostelium discoideum"
GO:0006704 : glucocorticoid biosynthetic process
xref
Reactome:REACT_96615 "Glucocorticoid biosynthesis, Caenorhabditis elegans"
xref
Reactome:REACT_112672 "Glucocorticoid biosynthesis, Plasmodium falciparum"
Reactome:REACT_113066 "Glucocorticoid biosynthesis, Escherichia coli"
GO:0006705 : mineralocorticoid biosynthetic process
xref
Reactome:REACT_107471 "Mineralocorticoid biosynthesis, Caenorhabditis elegans"
xref
Reactome:REACT_112957 "Mineralocorticoid biosynthesis, Escherichia coli"
Reactome:REACT_113805 "Mineralocorticoid biosynthesis, Mycobacterium tuberculosis"
GO:0006740 : NADPH regeneration
xref
Reactome:REACT_113557 "NADPH regeneration, Arabidopsis thaliana"
Reactome:REACT_114218 "NADPH regeneration, Plasmodium falciparum"
Reactome:REACT_115247 "NADPH regeneration, Oryza sativa"
GO:0006754 : ATP biosynthetic process
xref
Reactome:REACT_85973 "ADP and Pi bind to ATPase, Taeniopygia guttata"
Reactome:REACT_94502 "ATP is synthesized from ADP and Pi by ATPase, Taeniopygia guttata"
GO:0006769 : nicotinamide metabolic process
xref
Reactome:REACT_81936 "Nicotinamide salvaging, Plasmodium falciparum"
xref
Reactome:REACT_104665 "Nicotinamide salvaging, Plasmodium falciparum"
GO:0006778 : porphyrin-containing compound metabolic process
xref
Reactome:REACT_112552 "Metabolism of porphyrins, Caenorhabditis elegans"
GO:0006789 : bilirubin conjugation
xref
Reactome:REACT_85610 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Gallus gallus"
Reactome:REACT_94974 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Drosophila melanogaster"
Reactome:REACT_96026 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Xenopus tropicalis"
Reactome:REACT_96677 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Sus scrofa"
xref
Reactome:REACT_113946 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Caenorhabditis elegans"
Reactome:REACT_96239 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Sus scrofa"
GO:0006805 : xenobiotic metabolic process
xref
Reactome:REACT_102079 "Phase 1 - Functionalization of compounds, Sus scrofa"
Reactome:REACT_102277 "Biological oxidations, Sus scrofa"
Reactome:REACT_103704 "Conjugation of salicylate with glycine, Gallus gallus"
Reactome:REACT_28583 "Conjugation of carboxylic acids, Taeniopygia guttata"
Reactome:REACT_29864 "Conjugation of salicylate with glycine, Taeniopygia guttata"
Reactome:REACT_79356 "Conjugation of phenylacetate with glutamine, Gallus gallus"
Reactome:REACT_81348 "Amino Acid conjugation, Taeniopygia guttata"
Reactome:REACT_83267 "Conjugation of benzoate with glycine, Taeniopygia guttata"
Reactome:REACT_86211 "Conjugation of phenylacetate with glutamine, Danio rerio"
Reactome:REACT_89442 "Phase II conjugation, Sus scrofa"
Reactome:REACT_94547 "Amino Acid conjugation, Gallus gallus"
Reactome:REACT_97512 "Conjugation of benzoate with glycine, Gallus gallus"
Reactome:REACT_98034 "Conjugation of carboxylic acids, Gallus gallus"
Reactome:REACT_99732 "Conjugation of phenylacetate with glutamine, Taeniopygia guttata"
xref
Reactome:REACT_110976 "Biological oxidations, Sus scrofa"
Reactome:REACT_112180 "Conjugation of phenylacetate with glutamine, Dictyostelium discoideum"
Reactome:REACT_112300 "Amino Acid conjugation, Dictyostelium discoideum"
Reactome:REACT_112424 "Conjugation of salicylate with glycine, Dictyostelium discoideum"
Reactome:REACT_114132 "Conjugation of benzoate with glycine, Dictyostelium discoideum"
Reactome:REACT_115263 "Phase 1 - Functionalization of compounds, Escherichia coli"
Reactome:REACT_115368 "Conjugation of carboxylic acids, Dictyostelium discoideum"
Reactome:REACT_78563 "Phase 1 - Functionalization of compounds, Sus scrofa"
Reactome:REACT_89167 "Phase II conjugation, Sus scrofa"
GO:0006833 : water transport
xref
Reactome:REACT_100528 "Aquaporin-mediated transport, Saccharomyces cerevisiae"
Reactome:REACT_101266 "Aquaporin-mediated transport, Oryza sativa"
Reactome:REACT_28487 "Aquaporin-mediated transport, Arabidopsis thaliana"
Reactome:REACT_77446 "Passive Transport by Aquaporins, Arabidopsis thaliana"
Reactome:REACT_88899 "Regulation of Water Balance by Renal Aquaporins, Oryza sativa"
Reactome:REACT_94824 "Passive Transport by Aquaporins, Oryza sativa"
Reactome:REACT_98054 "Regulation of Water Balance by Renal Aquaporins, Arabidopsis thaliana"
xref
Reactome:REACT_108009 "Aquaporin-mediated transport, Saccharomyces cerevisiae"
Reactome:REACT_112337 "Passive Transport by Aquaporins, Escherichia coli"
Reactome:REACT_113611 "Passive Transport by Aquaporins, Drosophila melanogaster"
GO:0006853 : carnitine shuttle
xref
Reactome:REACT_108710 "Import of palmitoyl-CoA into the mitochondrial matrix, Plasmodium falciparum"
Reactome:REACT_77467 "Import of palmitoyl-CoA into the mitochondrial matrix, Sus scrofa"
xref
Reactome:REACT_84030 "Import of palmitoyl-CoA into the mitochondrial matrix, Sus scrofa"
GO:0006865 : amino acid transport
xref
Reactome:REACT_112073 "Amino acid transport across the plasma membrane, Mycobacterium tuberculosis"
Reactome:REACT_115423 "Amino acid transport across the plasma membrane, Saccharomyces cerevisiae"
GO:0006879 : cellular iron ion homeostasis
xref
Reactome:REACT_95122 "Iron uptake and transport, Dictyostelium discoideum"
xref
Reactome:REACT_113782 "Iron uptake and transport, Staphylococcus aureus N315"
Reactome:REACT_92578 "Iron uptake and transport, Dictyostelium discoideum"
GO:0006888 : ER to Golgi vesicle-mediated transport
xref
Reactome:REACT_97917 "ER to Golgi Transport, Caenorhabditis elegans"
GO:0006892 : post-Golgi vesicle-mediated transport
xref
Reactome:REACT_34456 "trans-Golgi Network Vesicle Budding, Saccharomyces cerevisiae"
GO:0006898 : receptor-mediated endocytosis
xref
Reactome:REACT_111177 "Movement of clathrin coated vesicles into early endosome, Homo sapiens"
Reactome:REACT_112262 "LDLR [endosome membrane] => LDLR [plasma membrane], Taeniopygia guttata"
Reactome:REACT_113143 "LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane], Taeniopygia guttata"
Reactome:REACT_113715 "LDLR [endosome membrane] => LDLR [plasma membrane], Drosophila melanogaster"
Reactome:REACT_114061 "LDLR:LDL complex => LDLR + LDL, Taeniopygia guttata"
Reactome:REACT_114157 "chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex, Xenopus tropicalis"
Reactome:REACT_114755 "LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent), Taeniopygia guttata"
Reactome:REACT_114861 "LDL + LDLR => LDL:LDLR complex, Taeniopygia guttata"
Reactome:REACT_115278 "LDL-mediated lipid transport, Caenorhabditis elegans"
Reactome:REACT_115471 "LDLR [endosome membrane] => LDLR [plasma membrane], Caenorhabditis elegans"
Reactome:REACT_115520 "LDL-mediated lipid transport, Drosophila melanogaster"
GO:0006915 : apoptosis
xref
Reactome:REACT_101916 "Apoptosis, Saccharomyces cerevisiae"
xref
Reactome:REACT_111964 "NRAGE signals death through JNK, Dictyostelium discoideum"
Reactome:REACT_28087 "Apoptosis, Saccharomyces cerevisiae"
GO:0006936 : muscle contraction
xref
Reactome:REACT_80035 "Smooth Muscle Contraction, Caenorhabditis elegans"
Reactome:REACT_90741 "Smooth Muscle Contraction, Dictyostelium discoideum"
Reactome:REACT_97034 "Smooth Muscle Contraction, Drosophila melanogaster"
xref
Reactome:REACT_92442 "Smooth Muscle Contraction, Dictyostelium discoideum"
GO:0006956 : complement activation
xref
Reactome:REACT_84310 "Activation of C3 and C5, Xenopus tropicalis"
GO:0006958 : complement activation, classical pathway
xref
Reactome:REACT_86322 "Classical antibody-mediated complement activation, Taeniopygia guttata"
Reactome:REACT_86543 "Classical antibody-mediated complement activation, Danio rerio"
Reactome:REACT_90437 "Classical antibody-mediated complement activation, Canis familiaris"
Reactome:REACT_91430 "Classical antibody-mediated complement activation, Gallus gallus"
GO:0006977 : DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
xref
Reactome:REACT_104601 "p53-Dependent G1 DNA Damage Response, Sus scrofa"
Reactome:REACT_99984 "p53-Dependent G1 DNA Damage Response, Dictyostelium discoideum"
xref
Reactome:REACT_33731 "p53-Dependent G1 DNA Damage Response, Dictyostelium discoideum"
Reactome:REACT_97071 "p53-Dependent G1 DNA Damage Response, Sus scrofa"
GO:0007004 : telomere maintenance via telomerase
xref
Reactome:REACT_101043 "Elongation Of The Telomeric Chromosome End, Saccharomyces cerevisiae"
Reactome:REACT_101432 "Recruitment of Telomerase RNP to the Telomeric Chromosome End, Dictyostelium discoideum"
Reactome:REACT_102517 "Disassociation of Telomerase RNP and the Chromosome End, Dictyostelium discoideum"
Reactome:REACT_105068 "Alignment Of The RNA Template On The Telomeric Chromosome End, Dictyostelium discoideum"
Reactome:REACT_109384 "Disassociation of Telomerase RNP and the Chromosome End, Saccharomyces cerevisiae"
Reactome:REACT_110598 "Alignment Of The RNA Template On The Telomeric Chromosome End, Sus scrofa"
Reactome:REACT_30302 "Elongation Of The Telomeric Chromosome End, Dictyostelium discoideum"
Reactome:REACT_30646 "Alignment Of The RNA Template On The Telomeric Chromosome End, Saccharomyces cerevisiae"
Reactome:REACT_32224 "Elongation of Extended Telomeric Chromosome End, Dictyostelium discoideum"
Reactome:REACT_33186 "Recruitment of Telomerase RNP to the Telomeric Chromosome End, Saccharomyces cerevisiae"
Reactome:REACT_77982 "Elongation Of The Telomeric Chromosome End, Sus scrofa"
Reactome:REACT_84958 "Elongation of Extended Telomeric Chromosome End, Saccharomyces cerevisiae"
Reactome:REACT_86897 "Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End, Dictyostelium discoideum"
Reactome:REACT_91666 "Disassociation of Telomerase RNP and the Chromosome End, Sus scrofa"
Reactome:REACT_93266 "Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End, Saccharomyces cerevisiae"
Reactome:REACT_95862 "Recruitment of Telomerase RNP to the Telomeric Chromosome End, Sus scrofa"
Reactome:REACT_98714 "Telomere Extension By Telomerase, Dictyostelium discoideum"
xref
Reactome:REACT_103846 "Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End, Saccharomyces cerevisiae"
Reactome:REACT_104705 "Elongation of Extended Telomeric Chromosome End, Saccharomyces cerevisiae"
Reactome:REACT_112155 "Alignment Of The RNA Template On The Telomeric Chromosome End, Xenopus tropicalis"
Reactome:REACT_112178 "Telomere Extension By Telomerase, Xenopus tropicalis"
Reactome:REACT_113385 "Elongation Of The Telomeric Chromosome End, Xenopus tropicalis"
Reactome:REACT_113614 "Recruitment of Telomerase RNP to the Telomeric Chromosome End, Xenopus tropicalis"
Reactome:REACT_114466 "Elongation of Extended Telomeric Chromosome End, Xenopus tropicalis"
Reactome:REACT_114887 "Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End, Xenopus tropicalis"
Reactome:REACT_115312 "Disassociation of Telomerase RNP and the Chromosome End, Xenopus tropicalis"
Reactome:REACT_30494 "Elongation Of The Telomeric Chromosome End, Sus scrofa"
Reactome:REACT_31549 "Elongation Of The Telomeric Chromosome End, Saccharomyces cerevisiae"
Reactome:REACT_90274 "Alignment Of The RNA Template On The Telomeric Chromosome End, Sus scrofa"
Reactome:REACT_91078 "Disassociation of Telomerase RNP and the Chromosome End, Sus scrofa"
Reactome:REACT_92196 "Alignment Of The RNA Template On The Telomeric Chromosome End, Saccharomyces cerevisiae"
Reactome:REACT_92694 "Recruitment of Telomerase RNP to the Telomeric Chromosome End, Sus scrofa"
Reactome:REACT_93253 "Disassociation of Telomerase RNP and the Chromosome End, Saccharomyces cerevisiae"
Reactome:REACT_99699 "Recruitment of Telomerase RNP to the Telomeric Chromosome End, Saccharomyces cerevisiae"
GO:0007018 : microtubule-based movement
xref
Reactome:REACT_88648 "Axonal transport of NGF:Trk complexes, Rattus norvegicus"
xref
Reactome:REACT_113466 "Axonal transport of NGF:Trk complexes, Caenorhabditis elegans"
GO:0007023 : post-chaperonin tubulin folding pathway
xref
Reactome:REACT_87963 "Post-chaperonin tubulin folding pathway, Schizosaccharomyces pombe"
Reactome:REACT_98225 "Post-chaperonin tubulin folding pathway, Saccharomyces cerevisiae"
xref
Reactome:REACT_112813 "Post-chaperonin tubulin folding pathway, Dictyostelium discoideum"
Reactome:REACT_113555 "Post-chaperonin tubulin folding pathway, Plasmodium falciparum"
Reactome:REACT_114764 "Post-chaperonin tubulin folding pathway, Caenorhabditis elegans"
Reactome:REACT_115188 "Post-chaperonin tubulin folding pathway, Arabidopsis thaliana"
Reactome:REACT_115383 "Post-chaperonin tubulin folding pathway, Oryza sativa"
GO:0007062 : sister chromatid cohesion
xref
Reactome:REACT_115472 "Phosphorylation of the SA2 Cohesion Complex, Schizosaccharomyces pombe"
GO:0007091 : mitotic metaphase/anaphase transition
xref
Reactome:REACT_113057 "Mitotic Metaphase/Anaphase Transition, Schizosaccharomyces pombe"
GO:0007092 : activation of mitotic anaphase-promoting complex activity
xref
Reactome:REACT_105360 "Activation of the Anaphase Promoting Complex (APC) by Plk1, Saccharomyces cerevisiae"
Reactome:REACT_79440 "Activation of the Anaphase Promoting Complex (APC) by Plk1, Dictyostelium discoideum"
xref
Reactome:REACT_86211 "Activation of the Anaphase Promoting Complex (APC) by Plk1, Saccharomyces cerevisiae"
Reactome:REACT_97458 "Activation of the Anaphase Promoting Complex (APC) by Plk1, Dictyostelium discoideum"
GO:0007094 : mitotic cell cycle spindle assembly checkpoint
xref
Reactome:REACT_108546 "Mitotic Spindle Checkpoint, Caenorhabditis elegans"
GO:0007165 : signal transduction
xref
Reactome:REACT_112130 "EGFR interacts with phospholipase C-gamma, Oryza sativa"
Reactome:REACT_112549 "EGFR interacts with phospholipase C-gamma, Arabidopsis thaliana"
Reactome:REACT_113151 "EGFR interacts with phospholipase C-gamma, Mycobacterium tuberculosis"
Reactome:REACT_113601 "EGFR interacts with phospholipase C-gamma, Drosophila melanogaster"
Reactome:REACT_113964 "EGFR interacts with phospholipase C-gamma, Bos taurus"
Reactome:REACT_114657 "EGFR interacts with phospholipase C-gamma, Dictyostelium discoideum"
Reactome:REACT_114690 "EGFR interacts with phospholipase C-gamma, Saccharomyces cerevisiae"
Reactome:REACT_114820 "EGFR interacts with phospholipase C-gamma, Sus scrofa"
Reactome:REACT_114910 "EGFR interacts with phospholipase C-gamma, Caenorhabditis elegans"
Reactome:REACT_115037 "EGFR interacts with phospholipase C-gamma, Plasmodium falciparum"
Reactome:REACT_115147 "EGFR interacts with phospholipase C-gamma, Schizosaccharomyces pombe"
GO:0007173 : epidermal growth factor receptor signaling pathway
xref
Reactome:REACT_112423 "Signaling by EGFR, Arabidopsis thaliana"
Reactome:REACT_114174 "Signaling by EGFR, Mycobacterium tuberculosis"
Reactome:REACT_114791 "Signaling by EGFR, Dictyostelium discoideum"
Reactome:REACT_114965 "Signaling by EGFR, Plasmodium falciparum"
Reactome:REACT_115105 "Signaling by EGFR, Oryza sativa"
GO:0007179 : transforming growth factor beta receptor signaling pathway
xref
Reactome:REACT_114882 "Signaling by TGF beta, Caenorhabditis elegans"
GO:0007189 : activation of adenylate cyclase activity by G-protein signaling pathway
xref
Reactome:REACT_80869 "Adenylate cyclase activating pathway, Dictyostelium discoideum"
GO:0007190 : activation of adenylate cyclase activity
xref
Reactome:REACT_98661 "Galpha-olf:GTP binds to adenylate cyclase and activates it, Dictyostelium discoideum"
GO:0007193 : inhibition of adenylate cyclase activity by G-protein signaling pathway
xref
Reactome:REACT_103667 "Adenylate cyclase inhibitory pathway, Dictyostelium discoideum"
Reactome:REACT_104417 "Adenylate cyclase inhibitory pathway, Caenorhabditis elegans"
GO:0007202 : activation of phospholipase C activity
xref
Reactome:REACT_34163 "PLC-gamma1 signalling, Sus scrofa"
xref
Reactome:REACT_114294 "PLC-gamma1 signalling, Plasmodium falciparum"
Reactome:REACT_114701 "PLC-gamma1 signalling, Oryza sativa"
Reactome:REACT_115230 "PLC-gamma1 signalling, Arabidopsis thaliana"
Reactome:REACT_98083 "PLC-gamma1 signalling, Sus scrofa"
GO:0007219 : Notch signaling pathway
xref
Reactome:REACT_107428 "Signaling by Notch, Sus scrofa"
xref
Reactome:REACT_76949 "Signaling by Notch, Sus scrofa"
GO:0007243 : intracellular protein kinase cascade
xref
Reactome:REACT_107888 "PKA-mediated phosphorylation of key metabolic factors, Drosophila melanogaster"
Reactome:REACT_85634 "PKA-mediated phosphorylation of key metabolic factors, Caenorhabditis elegans"
GO:0007254 : JNK cascade
xref
Reactome:REACT_32253 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1, Saccharomyces cerevisiae"
Reactome:REACT_79751 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1, Schizosaccharomyces pombe"
xref
Reactome:REACT_112172 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1, Arabidopsis thaliana"
Reactome:REACT_114741 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1, Oryza sativa"
Reactome:REACT_114745 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1, Dictyostelium discoideum"
GO:0007264 : small GTPase mediated signal transduction
xref
Reactome:REACT_113091 "Signalling to p38 via RIT and RIN, Oryza sativa"
Reactome:REACT_114399 "Signalling to p38 via RIT and RIN, Arabidopsis thaliana"
Reactome:REACT_115149 "Signalling to p38 via RIT and RIN, Dictyostelium discoideum"
GO:0007265 : Ras protein signal transduction
xref
Reactome:REACT_114204 "Signalling to RAS, Oryza sativa"
Reactome:REACT_114859 "Signalling to RAS, Arabidopsis thaliana"
Reactome:REACT_115010 "Signalling to RAS, Dictyostelium discoideum"
GO:0007268 : synaptic transmission
xref
Reactome:REACT_102748 "Synaptic Transmission, Saccharomyces cerevisiae"
Reactome:REACT_104894 "Synaptic Transmission, Xenopus tropicalis"
Reactome:REACT_13685 "Synaptic Transmission, Homo sapiens"
Reactome:REACT_29254 "Synaptic Transmission, Danio rerio"
Reactome:REACT_29595 "Synaptic Transmission, Caenorhabditis elegans"
Reactome:REACT_33322 "Synaptic Transmission, Taeniopygia guttata"
Reactome:REACT_33434 "Synaptic Transmission, Escherichia coli"
Reactome:REACT_77013 "Transmission across Chemical Synapses, Sus scrofa"
Reactome:REACT_78038 "Synaptic Transmission, Rattus norvegicus"
Reactome:REACT_78409 "Synaptic Transmission, Sus scrofa"
Reactome:REACT_80052 "Synaptic Transmission, Schizosaccharomyces pombe"
Reactome:REACT_82746 "Synaptic Transmission, Arabidopsis thaliana"
Reactome:REACT_86563 "Synaptic Transmission, Mus musculus"
Reactome:REACT_86628 "Synaptic Transmission, Canis familiaris"
Reactome:REACT_88599 "Synaptic Transmission, Bos taurus"
Reactome:REACT_88891 "Synaptic Transmission, Mycobacterium tuberculosis"
Reactome:REACT_89065 "Synaptic Transmission, Gallus gallus"
Reactome:REACT_89149 "Synaptic Transmission, Dictyostelium discoideum"
Reactome:REACT_89785 "Synaptic Transmission, Drosophila melanogaster"
Reactome:REACT_99952 "Synaptic Transmission, Oryza sativa"
xref
Reactome:REACT_102748 "Neuronal System, Saccharomyces cerevisiae"
Reactome:REACT_104894 "Neuronal System, Xenopus tropicalis"
Reactome:REACT_107151 "Neuronal System, Sus scrofa"
Reactome:REACT_112265 "Transmission across Chemical Synapses, Staphylococcus aureus N315"
Reactome:REACT_113444 "Neuronal System, Staphylococcus aureus N315"
Reactome:REACT_13685 "Neuronal System, Homo sapiens"
Reactome:REACT_29254 "Neuronal System, Danio rerio"
Reactome:REACT_29595 "Neuronal System, Caenorhabditis elegans"
Reactome:REACT_30266 "Transmission across Chemical Synapses, Sus scrofa"
Reactome:REACT_33322 "Neuronal System, Taeniopygia guttata"
Reactome:REACT_33434 "Neuronal System, Escherichia coli"
Reactome:REACT_78038 "Neuronal System, Rattus norvegicus"
Reactome:REACT_80052 "Neuronal System, Schizosaccharomyces pombe"
Reactome:REACT_82746 "Neuronal System, Arabidopsis thaliana"
Reactome:REACT_86563 "Neuronal System, Mus musculus"
Reactome:REACT_86628 "Neuronal System, Canis familiaris"
Reactome:REACT_88599 "Neuronal System, Bos taurus"
Reactome:REACT_88891 "Neuronal System, Mycobacterium tuberculosis"
Reactome:REACT_89065 "Neuronal System, Gallus gallus"
Reactome:REACT_89149 "Neuronal System, Dictyostelium discoideum"
Reactome:REACT_89785 "Neuronal System, Drosophila melanogaster"
Reactome:REACT_99952 "Neuronal System, Oryza sativa"
GO:0007269 : neurotransmitter secretion
xref
Reactome:REACT_95869 "Neurotransmitter Release Cycle, Sus scrofa"
xref
Reactome:REACT_110862 "Neurotransmitter Release Cycle, Sus scrofa"
Reactome:REACT_113329 "Neurotransmitter Release Cycle, Staphylococcus aureus N315"
Reactome:REACT_115061 "Neurotransmitter Release Cycle, Dictyostelium discoideum"
GO:0007411 : axon guidance
xref
Reactome:REACT_109333 "Axon guidance, Schizosaccharomyces pombe"
xref
Reactome:REACT_108197 "Axon guidance, Schizosaccharomyces pombe"
Reactome:REACT_112315 "Axon guidance, Plasmodium falciparum"
Reactome:REACT_114665 "Axon guidance, Arabidopsis thaliana"
Reactome:REACT_115127 "Axon guidance, Oryza sativa"
GO:0007588 : excretion
is_a
GO:0046903
GO:0007596 : blood coagulation
xref
Reactome:REACT_108655 "Hemostasis, Escherichia coli"
xref
Reactome:REACT_113650 "Common Pathway, Drosophila melanogaster"
Reactome:REACT_114152 "Formation of Fibrin Clot (Clotting Cascade), Drosophila melanogaster"
GO:0008028 : monocarboxylic acid transmembrane transporter activity
xref
Reactome:REACT_106228 "Na+-dependent monocarboxylate transport by SMCT, Rattus norvegicus"
Reactome:REACT_109633 "Na+-dependent monocarboxylate transport by SMCT, Mus musculus"
Reactome:REACT_29629 "Na+-dependent monocarboxylate transport by SMCT, Sus scrofa"
Reactome:REACT_29913 "Na+-dependent monocarboxylate transport by SMCT, Gallus gallus"
Reactome:REACT_31459 "Na+-dependent monocarboxylate transport by SMCT, Staphylococcus aureus N315"
Reactome:REACT_34564 "Na+-dependent monocarboxylate transport by SMCT, Xenopus tropicalis"
Reactome:REACT_82190 "Na+-dependent monocarboxylate transport by SMCT, Canis familiaris"
Reactome:REACT_85102 "Na+-dependent monocarboxylate transport by SMCT, Danio rerio"
Reactome:REACT_87687 "Na+-dependent monocarboxylate transport by SMCT, Bos taurus"
Reactome:REACT_93426 "Na+-dependent monocarboxylate transport by SMCT, Taeniopygia guttata"
xref
Reactome:REACT_114096 "MCTs mediate proton-coupled transport of monocarboxylates and ketone bodies, Drosophila melanogaster"
Reactome:REACT_115467 "MCTs mediate proton-coupled transport of monocarboxylates and ketone bodies, Saccharomyces cerevisiae"
GO:0008029 : pentraxin receptor activity
is_a
GO:0001864
relationship
has_part GO:0001864
GO:0008061 : chitin binding
def
Interacting selectively and non-covalently with chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues.
def
Interacting selectively and non-covalently with chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.
GO:0008063 : Toll signaling pathway
xref
Reactome:REACT_79117 "Toll Like Receptor 4 (TLR4) Cascade, Caenorhabditis elegans"
xref
Reactome:REACT_109528 "Toll Like Receptor 4 (TLR4) Cascade, Caenorhabditis elegans"
GO:0008066 : glutamate receptor activity
relationship
has_part GO:0016595
GO:0008116 : prostaglandin-I synthase activity
xref
Reactome:REACT_112323 "Prostacyclin synthase (CYP8A1) mediates the isomerization of prostaglandin H2 to prostaglandin I2, Mycobacterium tuberculosis"
Reactome:REACT_113532 "Prostacyclin synthase (CYP8A1) mediates the isomerization of prostaglandin H2 to prostaglandin I2, Arabidopsis thaliana"
Reactome:REACT_114097 "Prostacyclin synthase (CYP8A1) mediates the isomerization of prostaglandin H2 to prostaglandin I2, Dictyostelium discoideum"
Reactome:REACT_114523 "Prostacyclin synthase (CYP8A1) mediates the isomerization of prostaglandin H2 to prostaglandin I2, Oryza sativa"
GO:0008117 : sphinganine-1-phosphate aldolase activity
xref
Reactome:REACT_113234 "sphinganine 1-phosphate => phosphoethanolamine + hexadecanal, Caenorhabditis elegans"
Reactome:REACT_113298 "sphinganine 1-phosphate => phosphoethanolamine + hexadecanal, Escherichia coli"
Reactome:REACT_113335 "sphingosine 1-phosphate => phosphoethanolamine + hexadec-2-enal, Caenorhabditis elegans"
Reactome:REACT_114175 "sphingosine 1-phosphate => phosphoethanolamine + hexadec-2-enal, Escherichia coli"
GO:0008119 : thiopurine S-methyltransferase activity
xref
Reactome:REACT_96049 "6-mercaptopurine can be S-methylated, Sus scrofa"
xref
Reactome:REACT_30624 "6-mercaptopurine can be S-methylated, Sus scrofa"
GO:0008123 : cholesterol 7-alpha-monooxygenase activity
xref
Reactome:REACT_112443 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Mycobacterium tuberculosis"
Reactome:REACT_113215 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Arabidopsis thaliana"
Reactome:REACT_114538 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Oryza sativa"
Reactome:REACT_114617 "Cholesterol is hydroxylated to 7alpha-hydroxycholesterol by CYP7A1, Dictyostelium discoideum"
GO:0008124 : 4-alpha-hydroxytetrahydrobiopterin dehydratase activity
xref
Reactome:REACT_113243 "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O, Caenorhabditis elegans"
GO:0008131 : primary amine oxidase activity
xref
Reactome:REACT_30414 "Oxidation of 3-Methoxytyramine to homovanillic acid, Bos taurus"
Reactome:REACT_77866 "Dietary tyramine is oxidatively deaminated to an aldehyde by MAOB, Gallus gallus"
Reactome:REACT_78571 "oxidation of dopamine to 3,4dihydroxyphenylacetic acid (DOPAC), Bos taurus"
xref
Reactome:REACT_100172 "oxidation of dopamine to 3,4dihydroxyphenylacetic acid (DOPAC), Bos taurus"
Reactome:REACT_104381 "Oxidation of 3-Methoxytyramine to homovanillic acid, Bos taurus"
Reactome:REACT_112132 "Oxidative deamination of 5-Hydroxytryptamine by MAOA, Dictyostelium discoideum"
Reactome:REACT_112188 "oxidation of dopamine to 3,4dihydroxyphenylacetic acid (DOPAC), Dictyostelium discoideum"
Reactome:REACT_112919 "Oxidative deamination of Phenyethylamine by MAOB, Dictyostelium discoideum"
Reactome:REACT_113622 "Dietary tyramine is oxidatively deaminated to an aldehyde by MAOB, Dictyostelium discoideum"
Reactome:REACT_114320 "Oxidation of 3-Methoxytyramine to homovanillic acid, Dictyostelium discoideum"
Reactome:REACT_115498 "Metabolism of Noradrenaline, Dictyostelium discoideum"
GO:0008146 : sulfotransferase activity
xref
Reactome:REACT_87853 "taurolithocholate + PAPS => taurolithocholate sulfate + PAP, Danio rerio"
Reactome:REACT_92241 "N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP, Taeniopygia guttata"
Reactome:REACT_92715 "lithocholate + PAPS => lithocholate sulfate + PAP, Danio rerio"
Reactome:REACT_93270 "N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP, Gallus gallus"
xref
Reactome:REACT_113711 "N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP, Danio rerio"
GO:0008158 : hedgehog receptor activity
def
Combining with the hedgehog protein to initiate a change in cell activity.
def
Combining with a hedgehog protein to initiate a change in cell activity.
relationship
has_part GO:0097108
GO:0008168 : methyltransferase activity
xref
Reactome:REACT_80424 "Methylation of 3,4-dihydroxypheylacetic acid to homovanillic acid, Bos taurus"
Reactome:REACT_80832 "methylation of Dopamine to form 3-Methoxytyramine, Bos taurus"
xref
Reactome:REACT_100745 "Methylation of 3,4-dihydroxypheylacetic acid to homovanillic acid, Bos taurus"
Reactome:REACT_29020 "methylation of Dopamine to form 3-Methoxytyramine, Bos taurus"
GO:0008173 : RNA methyltransferase activity
xref
Reactome:REACT_88299 "snRNA Cap hypermethylation, Sus scrofa"
GO:0008177 : succinate dehydrogenase (ubiquinone) activity
xref
Reactome:REACT_91586 "Transfer of electrons through the succinate dehydrogenase complex, Saccharomyces cerevisiae"
xref
Reactome:REACT_88562 "Transfer of electrons through the succinate dehydrogenase complex, Saccharomyces cerevisiae"
GO:0008179 : adenylate cyclase binding
xref
Reactome:REACT_98661 "Galpha-olf:GTP binds to adenylate cyclase and activates it, Dictyostelium discoideum"
GO:0008184 : glycogen phosphorylase activity
xref
Reactome:REACT_84225 "glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL], Saccharomyces cerevisiae"
xref
Reactome:REACT_107584 "glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL], Saccharomyces cerevisiae"
Reactome:REACT_112008 "poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB], Caenorhabditis elegans"
Reactome:REACT_112419 "poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL], Danio rerio"
Reactome:REACT_112518 "glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL], Arabidopsis thaliana"
Reactome:REACT_112595 "glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB], Arabidopsis thaliana"
Reactome:REACT_112994 "poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL], Caenorhabditis elegans"
Reactome:REACT_113339 "poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB], Arabidopsis thaliana"
Reactome:REACT_113449 "poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL], Arabidopsis thaliana"
Reactome:REACT_113915 "glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL], Caenorhabditis elegans"
Reactome:REACT_114127 "glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB], Caenorhabditis elegans"
Reactome:REACT_114709 "glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB], Xenopus tropicalis"
Reactome:REACT_114725 "poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB], Xenopus tropicalis"
Reactome:REACT_115476 "glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL], Danio rerio"
GO:0008188 : neuropeptide receptor activity
is_a
GO:0042923
relationship
has_part GO:0042923
GO:0008194 : UDP-glycosyltransferase activity
xref
Reactome:REACT_89213 "phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP, Sus scrofa"
xref
Reactome:REACT_92152 "phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP, Sus scrofa"
GO:0008195 : phosphatidate phosphatase activity
xref
Reactome:REACT_102146 "Dephosphorylation of AKT by PP2A, Dictyostelium discoideum"
xref
Reactome:REACT_112281 "1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate, Drosophila melanogaster"
GO:0008201 : heparin binding
def
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha1-4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
def
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
GO:0008202 : steroid metabolic process
xref
Reactome:REACT_31074 "Metabolism of steroid hormones and vitamins A and D, Plasmodium falciparum"
xref
Reactome:REACT_97355 "Metabolism of steroid hormones and vitamins A and D, Plasmodium falciparum"
GO:0008206 : bile acid metabolic process
xref
Reactome:REACT_28750 "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine, Sus scrofa"
xref
Reactome:REACT_113960 "Bile acid and bile salt metabolism, Plasmodium falciparum"
Reactome:REACT_115499 "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine, Gallus gallus"
Reactome:REACT_99705 "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine, Sus scrofa"
GO:0008215 : spermine metabolic process
xref
Reactome:REACT_78052 "Spermine is oxidized to spermidine, Saccharomyces cerevisiae"
xref
Reactome:REACT_114114 "Spermine is oxidized to spermidine, Caenorhabditis elegans"
Reactome:REACT_114150 "Spermine is oxidized to spermidine, Drosophila melanogaster"
Reactome:REACT_84703 "Spermine is oxidized to spermidine, Saccharomyces cerevisiae"
GO:0008237 : metallopeptidase activity
xref
Reactome:REACT_104946 "Notch 2-ligand complex is cleaved to produce NEXT2, Taeniopygia guttata"
Reactome:REACT_106676 "Notch 2-ligand complex is cleaved to produce NEXT2, Sus scrofa"
Reactome:REACT_90446 "Notch 4-ligand complex is cleaved to produce NEXT4, Sus scrofa"
xref
Reactome:REACT_100129 "Notch 4-ligand complex is cleaved to produce NEXT4, Sus scrofa"
Reactome:REACT_114094 "Notch 3-ligand complex is cleaved to produce NEXT3, Drosophila melanogaster"
Reactome:REACT_115138 "Notch 4-ligand complex is cleaved to produce NEXT4, Xenopus tropicalis"
Reactome:REACT_83310 "Notch 2-ligand complex is cleaved to produce NEXT2, Sus scrofa"
GO:0008253 : 5'-nucleotidase activity
xref
Reactome:REACT_77651 "CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E], Drosophila melanogaster"
Reactome:REACT_81698 "AMP, dAMP, GMP, or IMP + H2O => adenosine, deoxyadenosine, guanosine, or inosine + orthophosphate [NT5E], Drosophila melanogaster"
GO:0008260 : 3-oxoacid CoA-transferase activity
xref
Reactome:REACT_101965 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Rattus norvegicus"
Reactome:REACT_110993 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Bos taurus"
Reactome:REACT_1796 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Homo sapiens"
Reactome:REACT_28387 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Gallus gallus"
Reactome:REACT_31223 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Danio rerio"
Reactome:REACT_33458 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Caenorhabditis elegans"
Reactome:REACT_81222 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Drosophila melanogaster"
Reactome:REACT_82464 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Mycobacterium tuberculosis"
Reactome:REACT_86080 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Mus musculus"
Reactome:REACT_88464 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Dictyostelium discoideum"
Reactome:REACT_89608 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Canis familiaris"
Reactome:REACT_90429 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Taeniopygia guttata"
Reactome:REACT_90587 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Escherichia coli"
Reactome:REACT_95458 "acetoacetate+succinyl-CoA <=> acetoacetyl-CoA+succinate, Sus scrofa"
xref
Reactome:REACT_101965 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Rattus norvegicus"
Reactome:REACT_110993 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Bos taurus"
Reactome:REACT_112252 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Xenopus tropicalis"
Reactome:REACT_1796 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Homo sapiens"
Reactome:REACT_28387 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Gallus gallus"
Reactome:REACT_31223 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Danio rerio"
Reactome:REACT_33458 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Caenorhabditis elegans"
Reactome:REACT_81222 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Drosophila melanogaster"
Reactome:REACT_82464 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Mycobacterium tuberculosis"
Reactome:REACT_86080 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Mus musculus"
Reactome:REACT_88464 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Dictyostelium discoideum"
Reactome:REACT_89608 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Canis familiaris"
Reactome:REACT_90429 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Taeniopygia guttata"
Reactome:REACT_95458 "acetoacetate + succinyl-CoA <=> acetoacetyl-CoA + succinate, Sus scrofa"
GO:0008262 : importin-alpha export receptor activity
is_a
GO:0008565
GO:0008286 : insulin receptor signaling pathway
xref
Reactome:REACT_108250 "Signaling by Insulin receptor, Dictyostelium discoideum"
xref
Reactome:REACT_103763 "Signaling by Insulin receptor, Dictyostelium discoideum"
GO:0008294 : calcium- and calmodulin-responsive adenylate cyclase activity
xref
Reactome:REACT_104598 "Adenylate cyclase produces cAMP, Dictyostelium discoideum"
GO:0008321 : Ral guanyl-nucleotide exchange factor activity
xref
Reactome:REACT_87405 "Guanine nucleotide exchange on Ral, Caenorhabditis elegans"
xref
Reactome:REACT_111942 "Guanine nucleotide exchange on Ral, Xenopus tropicalis"
Reactome:REACT_115506 "Guanine nucleotide exchange on Ral, Taeniopygia guttata"
GO:0008329 : pattern recognition receptor activity
relationship
has_part GO:0001871
GO:0008334 : histone mRNA metabolic process
xref
Reactome:REACT_103016 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs, Sus scrofa"
Reactome:REACT_105929 "Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA, Sus scrofa"
Reactome:REACT_81694 "Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA, Sus scrofa"
Reactome:REACT_90689 "SLBP independent Processing of Histone Pre-mRNAs, Sus scrofa"
xref
Reactome:REACT_112727 "SLBP independent Processing of Histone Pre-mRNAs, Danio rerio"
Reactome:REACT_112752 "Binding of SLBP to Replication-Dependent Histone Pre-mRNA, Caenorhabditis elegans"
Reactome:REACT_112829 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs, Caenorhabditis elegans"
Reactome:REACT_113324 "Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA, Danio rerio"
Reactome:REACT_113499 "Binding of SLBP to Replication-Dependent Histone Pre-mRNA, Dictyostelium discoideum"
Reactome:REACT_113687 "Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA, Caenorhabditis elegans"
Reactome:REACT_113849 "Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA, Drosophila melanogaster"
Reactome:REACT_113897 "Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA, Drosophila melanogaster"
Reactome:REACT_114009 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs, Drosophila melanogaster"
Reactome:REACT_114040 "SLBP independent Processing of Histone Pre-mRNAs, Drosophila melanogaster"
Reactome:REACT_114133 "Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA, Caenorhabditis elegans"
Reactome:REACT_114241 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs, Dictyostelium discoideum"
Reactome:REACT_115024 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs, Danio rerio"
Reactome:REACT_115064 "Binding of SLBP to Replication-Dependent Histone Pre-mRNA, Drosophila melanogaster"
Reactome:REACT_115116 "Binding of SLBP to Replication-Dependent Histone Pre-mRNA, Danio rerio"
Reactome:REACT_115510 "Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA, Danio rerio"
Reactome:REACT_115517 "SLBP independent Processing of Histone Pre-mRNAs, Caenorhabditis elegans"
Reactome:REACT_84828 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs, Sus scrofa"
GO:0008336 : gamma-butyrobetaine dioxygenase activity
xref
Reactome:REACT_114022 "gamma-butyrobetaine + alpha-ketoglutarate + O2 => carnitine + succinate + CO2, Saccharomyces cerevisiae"
GO:0008374 : O-acyltransferase activity
xref
Reactome:REACT_28943 "glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH, Saccharomyces cerevisiae"
Reactome:REACT_84008 "glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH, Sus scrofa"
xref
Reactome:REACT_78639 "glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH, Saccharomyces cerevisiae"
Reactome:REACT_90799 "glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH, Sus scrofa"
GO:0008380 : RNA splicing
xref
Reactome:REACT_113880 "mRNA Splicing, Taeniopygia guttata"
GO:0008386 : cholesterol monooxygenase (side-chain-cleaving) activity
xref
Reactome:REACT_28582 "Oxidation of cholesterol to 22beta-hydroxycholesterol, Caenorhabditis elegans"
Reactome:REACT_34495 "20alpha,22beta-hydroxycholesterol is cleaved by CYP11A1 to yield pregnenolone and isocaproaldehyde, Caenorhabditis elegans"
Reactome:REACT_79782 "Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol, Caenorhabditis elegans"
GO:0008389 : coumarin 7-hydroxylase activity
xref
Reactome:REACT_108785 "Coumarin is 7-hydroxylated by CYP2A13, Sus scrofa"
Reactome:REACT_88845 "Coumarin is 7-hydroxylated by CYP2A13, Canis familiaris"
xref
Reactome:REACT_112622 "Coumarin is 7-hydroxylated by CYP2A6, Xenopus tropicalis"
Reactome:REACT_112822 "Coumarin is 7-hydroxylated by CYP2A6, Danio rerio"
Reactome:REACT_113359 "Coumarin is 7-hydroxylated by CYP2A6, Mus musculus"
Reactome:REACT_113450 "Coumarin is 7-hydroxylated by CYP2A6, Rattus norvegicus"
GO:0008395 : steroid hydroxylase activity
xref
Reactome:REACT_102026 "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA), Caenorhabditis elegans"
Reactome:REACT_102407 "5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al, Caenorhabditis elegans"
Reactome:REACT_103979 "3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA), Caenorhabditis elegans"
Reactome:REACT_104501 "Cholesterol is hydroxylated to 27-hydroxycholesterol by CYP27, Caenorhabditis elegans"
Reactome:REACT_108033 "Hydroxylation of corticosterone to form 18-hydroxycorticosterone, Caenorhabditis elegans"
Reactome:REACT_108747 "5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al, Caenorhabditis elegans"
Reactome:REACT_34510 "5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al, Caenorhabditis elegans"
Reactome:REACT_78684 "Conversion of 18-hydroxycorticosterone to aldosterone, Caenorhabditis elegans"
Reactome:REACT_80351 "5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al, Caenorhabditis elegans"
Reactome:REACT_83402 "5beta-cholestan-3alpha, 7alpha, 12alpha-triol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 12alpha, 27-tetrol, Caenorhabditis elegans"
Reactome:REACT_86874 "3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA), Caenorhabditis elegans"
Reactome:REACT_88364 "5beta-cholestan-3alpha,7alpha,24(S)-triol is hydroxylated to 5beta-cholestan-3alpha,7alpha,24(S), 27-tetrol, Caenorhabditis elegans"
Reactome:REACT_89675 "5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol, Sus scrofa"
Reactome:REACT_90245 "5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol, Caenorhabditis elegans"
Reactome:REACT_92991 "5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol, Caenorhabditis elegans"
Reactome:REACT_94011 "3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA), Caenorhabditis elegans"
xref
Reactome:REACT_112201 "Cholesterol is hydroxylated to 25-hydroxycholesterol, Xenopus tropicalis"
Reactome:REACT_28778 "5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol, Sus scrofa"
GO:0008396 : oxysterol 7-alpha-hydroxylase activity
xref
Reactome:REACT_112158 "24-hydroxycholesterol is 7alpha-hydroxylated to yield cholest-5-ene-3beta,7alpha,24-triol, Dictyostelium discoideum"
Reactome:REACT_112291 "25-hydroxycholesterol is 7alpha-hydroxylated by CYP7B1, Oryza sativa"
Reactome:REACT_112636 "27-hydroxycholesterol is 7alpha-hydroxylated, Arabidopsis thaliana"
Reactome:REACT_112857 "27-hydroxycholesterol is 7alpha-hydroxylated, Dictyostelium discoideum"
Reactome:REACT_113559 "27-hydroxycholesterol is 7alpha-hydroxylated, Oryza sativa"
Reactome:REACT_113710 "27-hydroxycholesterol is 7alpha-hydroxylated, Mycobacterium tuberculosis"
Reactome:REACT_114515 "25-hydroxycholesterol is 7alpha-hydroxylated by CYP7B1, Dictyostelium discoideum"
Reactome:REACT_114585 "24-hydroxycholesterol is 7alpha-hydroxylated to yield cholest-5-ene-3beta,7alpha,24-triol, Arabidopsis thaliana"
Reactome:REACT_114797 "25-hydroxycholesterol is 7alpha-hydroxylated by CYP7B1, Arabidopsis thaliana"
Reactome:REACT_114849 "25-hydroxycholesterol is 7alpha-hydroxylated by CYP7B1, Mycobacterium tuberculosis"
Reactome:REACT_115480 "24-hydroxycholesterol is 7alpha-hydroxylated to yield cholest-5-ene-3beta,7alpha,24-triol, Oryza sativa"
Reactome:REACT_115504 "24-hydroxycholesterol is 7alpha-hydroxylated to yield cholest-5-ene-3beta,7alpha,24-triol, Mycobacterium tuberculosis"
GO:0008398 : sterol 14-demethylase activity
xref
Reactome:REACT_88673 "Lanosterol is oxidatively demethylated to 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol, Sus scrofa"
Reactome:REACT_98968 "Lanosterol is oxidatively demethylated to 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol, Rattus norvegicus"
xref
Reactome:REACT_29216 "Lanosterol is oxidatively demethylated to 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol, Sus scrofa"
GO:0008407 : chaeta morphogenesis
name
bristle morphogenesis
def
The process in which the anatomical structures of the bristle are generated and organized.
name
chaeta morphogenesis
def
The process in which the anatomical structures of the chaeta are generated and organized. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.
synonym
"bristle morphogenesis" NARROW [GOC:bf, GOC:dos]
GO:0008424 : glycoprotein 6-alpha-L-fucosyltransferase activity
synonym
"GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1,6)fucosyltransferase activity" EXACT [EC:2.4.1.68]
"GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1,6)fucosyltransferase activity" EXACT [EC:2.4.1.68]
GO:0008442 : 3-hydroxyisobutyrate dehydrogenase activity
xref
Reactome:REACT_87005 "beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+, Caenorhabditis elegans"
xref
Reactome:REACT_95495 "beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+, Caenorhabditis elegans"
GO:0008455 : alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
synonym
"UDP-GlcNAc:mannoside alpha-1-6 acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143]
"UDP-GlcNAc:mannoside alpha1-6 acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143]
"uridine diphosphoacetylglucosamine-alpha-1,6-mannosylglycoprotein beta-1-2-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143]
"uridine diphosphoacetylglucosamine-alpha-D-mannoside beta-1-2-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143]
"uridine diphosphoacetylglucosamine-alpha-D-mannoside beta1-2-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143]
"uridine diphosphoacetylglucosamine-mannoside alpha-1->6-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143]
"uridine diphosphoacetylglucosamine-mannoside alpha1->6-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143]
synonym
"UDP-GlcNAc:mannoside alpha-(1,6) acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143]
"UDP-GlcNAc:mannoside alpha-1,6 acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143]
"uridine diphosphoacetylglucosamine-alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143]
"uridine diphosphoacetylglucosamine-alpha-D-mannoside beta(1,2)-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143]
"uridine diphosphoacetylglucosamine-alpha-D-mannoside beta-1,2-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143]
"uridine diphosphoacetylglucosamine-mannoside alpha(1,6)-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143]
"uridine diphosphoacetylglucosamine-mannoside alpha-1,6-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.143]
GO:0008466 : glycogenin glucosyltransferase activity
xref
Reactome:REACT_113130 "8 UDP-glucose + glycogenin dimer => 8 UDP + {(1,4)-alpha-D-glucosyl}4 glycogenin dimer, Arabidopsis thaliana"
GO:0008470 : isovaleryl-CoA dehydrogenase activity
xref
Reactome:REACT_77372 "isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2, Caenorhabditis elegans"
xref
Reactome:REACT_28761 "isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2, Caenorhabditis elegans"
GO:0008481 : sphinganine kinase activity
xref
Reactome:REACT_112755 "sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP, Caenorhabditis elegans"
GO:0008496 : mannan endo-1,6-alpha-mannosidase activity
def
Catalysis of the random hydrolysis of 1,6-alpha-D-mannosidic linkages in unbranched 1,6-mannans.
def
Catalysis of the random hydrolysis of (1->6)-alpha-D-mannosidic linkages in unbranched (1->6)-mannans.
GO:0008504 : monoamine transmembrane transporter activity
xref
Reactome:REACT_101967 "Reuptake of dopamine from the synaptic cleft into neurons, Caenorhabditis elegans"
Reactome:REACT_105284 "Reuptake of dopamine from the synaptic cleft into neurons, Drosophila melanogaster"
Reactome:REACT_109976 "loading of Serotonin in synaptic vesicles, Xenopus tropicalis"
Reactome:REACT_80372 "Reuptake of dopamine from the synaptic cleft into neurons, Bos taurus"
Reactome:REACT_91449 "Loading of dopamine into synaptic veiscles, Xenopus tropicalis"
xref
Reactome:REACT_30134 "Reuptake of dopamine from the synaptic cleft into neurons, Bos taurus"
GO:0008508 : bile acid:sodium symporter activity
xref
Reactome:REACT_28793 "Co-transport (influx) of bile salts and sodium ions by NTCP, Gallus gallus"
xref
Reactome:REACT_112308 "SOAT can transport taurolithocholate-3-sulphate, Staphylococcus aureus N315"
Reactome:REACT_114282 "Co-transport (influx) of bile salts and acids and sodium ions by ASBT, Xenopus tropicalis"
Reactome:REACT_114427 "Co-transport (influx) of bile salts and sodium ions by NTCP, Danio rerio"
Reactome:REACT_114684 "Co-transport (influx) of bile salts and sodium ions by NTCP, Xenopus tropicalis"
GO:0008510 : sodium:bicarbonate symporter activity
xref
Reactome:REACT_92350 "Na+-coupled HCO3- cotransport, Sus scrofa"
xref
Reactome:REACT_113404 "Na+-coupled HCO3- cotransport, Dictyostelium discoideum"
Reactome:REACT_86222 "Na+-coupled HCO3- cotransport, Sus scrofa"
GO:0008517 : folic acid transporter activity
xref
Reactome:REACT_108089 "Cytosolic tetrahydrofolate import across the inner mitochondrial membrane, Dictyostelium discoideum"
Reactome:REACT_83407 "Mitochondrial tetrahydrofolate export across the inner mitochondrial membrane, Sus scrofa"
xref
Reactome:REACT_90989 "Mitochondrial tetrahydrofolate export across the inner mitochondrial membrane, Sus scrofa"
Reactome:REACT_98444 "Cytosolic tetrahydrofolate import across the inner mitochondrial membrane, Dictyostelium discoideum"
GO:0008523 : sodium-dependent multivitamin transmembrane transporter activity
xref
Reactome:REACT_108516 "Biotin transport across the plasma membrane, Sus scrofa"
xref
Reactome:REACT_83124 "Biotin transport across the plasma membrane, Sus scrofa"
GO:0008531 : riboflavin kinase activity
xref
Reactome:REACT_114647 "Riboflavin is phosphorylated to FMN, Canis familiaris"
GO:0008532 : N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity
synonym
"N-acetyllactosamine beta(1-3)N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.149]
"UDP-GlcNAc:Galbeta1->4GlcNAcbeta-rbeta1->3-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.149]
synonym
"N-acetyllactosamine beta(1,3)N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.149]
"UDP-GlcNAc:Galbeta-(1,4)-GlcNAcbeta-r-beta-(1,3)-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.149]
"UDP-GlcNAc:Galbeta-1,4-GlcNAcbeta-beta-1,3-N-acetylglucosaminyltransferase activity" EXACT [EC:2.4.1.149]
"uridine diphosphoacetylglucosamine-acetyllactosaminide beta-1,3-acetylglucosaminyltransferase" BROAD [EC:2.4.1.149]
GO:0008534 : oxidized purine base lesion DNA N-glycosylase activity
synonym
"fapy-DNA glycosylase activity" EXACT [EC:3.2.2.23]
xref
Reactome:REACT_103037 "Cleavage of formamidopyrimidine by hOGG1 glycosylase, Taeniopygia guttata"
Reactome:REACT_107147 "Cleavage of formamidopyrimidine by hOGG1 glycosylase, Xenopus tropicalis"
Reactome:REACT_31170 "Cleavage of 8-oxo guanine by hOGG1 glycosylase, Saccharomyces cerevisiae"
Reactome:REACT_90804 "Cleavage of formamidopyrimidine by hOGG1 glycosylase, Saccharomyces cerevisiae"
Reactome:REACT_93002 "Cleavage of 8-oxo guanine by hOGG1 glycosylase, Taeniopygia guttata"
Reactome:REACT_93190 "Cleavage of 8-oxo guanine by hOGG1 glycosylase, Xenopus tropicalis"
xref
Reactome:REACT_28730 "Cleavage of 8-oxo guanine by hOGG1 glycosylase, Saccharomyces cerevisiae"
Reactome:REACT_88552 "Cleavage of formamidopyrimidine by hOGG1 glycosylase, Saccharomyces cerevisiae"
GO:0008543 : fibroblast growth factor receptor signaling pathway
xref
Reactome:REACT_83604 "Signaling by FGFR, Sus scrofa"
xref
Reactome:REACT_102813 "Signaling by FGFR, Sus scrofa"
Reactome:REACT_112148 "FGFR1b ligand binding and activation, Drosophila melanogaster"
Reactome:REACT_112458 "Signaling by FGFR, Mycobacterium tuberculosis"
Reactome:REACT_112770 "FGFR2 ligand binding and activation, Caenorhabditis elegans"
Reactome:REACT_113040 "FGFR1c ligand binding and activation, Caenorhabditis elegans"
Reactome:REACT_113367 "Signaling by FGFR, Plasmodium falciparum"
Reactome:REACT_113498 "FGFR3b ligand binding and activation, Caenorhabditis elegans"
Reactome:REACT_113682 "FGFR3c ligand binding and activation, Caenorhabditis elegans"
Reactome:REACT_114115 "FGFR3 ligand binding and activation, Caenorhabditis elegans"
Reactome:REACT_114162 "FGFR2b ligand binding and activation, Caenorhabditis elegans"
Reactome:REACT_114328 "Signaling by FGFR, Saccharomyces cerevisiae"
Reactome:REACT_114758 "FGFR2c ligand binding and activation, Caenorhabditis elegans"
Reactome:REACT_114804 "FGFR2b ligand binding and activation, Drosophila melanogaster"
Reactome:REACT_115170 "FGFR1 ligand binding and activation, Caenorhabditis elegans"
Reactome:REACT_115181 "Signaling by FGFR, Schizosaccharomyces pombe"
Reactome:REACT_115307 "FGFR1b ligand binding and activation, Caenorhabditis elegans"
Reactome:REACT_115350 "FGFR4 ligand binding and activation, Caenorhabditis elegans"
Reactome:REACT_115356 "FGFR ligand binding and activation, Caenorhabditis elegans"
GO:0008545 : JUN kinase kinase activity
xref
Reactome:REACT_31247 "Phosphorylation of human JNKs by activated MKK4/MKK7, Schizosaccharomyces pombe"
Reactome:REACT_81103 "Phosphorylation of human JNKs by activated MKK4/MKK7, Saccharomyces cerevisiae"
Reactome:REACT_82185 "Phosphorylation of human JNKs by activated MKK4/MKK7, Caenorhabditis elegans"
xref
Reactome:REACT_112463 "Phosphorylation of human JNKs by activated MKK4/MKK7, Arabidopsis thaliana"
Reactome:REACT_114469 "Phosphorylation of human JNKs by activated MKK4/MKK7, Dictyostelium discoideum"
Reactome:REACT_114896 "Phosphorylation of human JNKs by activated MKK4/MKK7, Oryza sativa"
Reactome:REACT_99661 "Phosphorylation of human JNKs by activated MKK4/MKK7, Caenorhabditis elegans"
GO:0008551 : cadmium-exporting ATPase activity
synonym
"cd2+-exporting ATPase activity" EXACT [EC:3.6.3.3]
GO:0008555 : chloride-transporting ATPase activity
synonym
"cl--transporting ATPase activity" EXACT [EC:3.6.3.11]
GO:0008559 : xenobiotic-transporting ATPase activity
xref
Reactome:REACT_111164 "ABCA8, B1 and B5 mediate xenobiotic efflux, Homo sapiens"
GO:0008597 : calcium-dependent protein serine/threonine phosphatase regulator activity
xref
Reactome:REACT_113351 "Activation of BAD by calcineurin, Xenopus tropicalis"
Reactome:REACT_113411 "Activation of BAD by calcineurin, Rattus norvegicus"
GO:0008599 : protein phosphatase type 1 regulator activity
xref
Reactome:REACT_32210 "DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function, Bos taurus"
xref
Reactome:REACT_110300 "DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function, Bos taurus"
GO:0008609 : alkylglycerone-phosphate synthase activity
xref
Reactome:REACT_114920 "1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate, Escherichia coli"
Reactome:REACT_115040 "1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate, Mycobacterium tuberculosis"
GO:0008611 : ether lipid biosynthetic process
xref
Reactome:REACT_112332 "Plasmalogen biosynthesis, Mycobacterium tuberculosis"
Reactome:REACT_112578 "Plasmalogen biosynthesis, Escherichia coli"
GO:0008612 : peptidyl-lysine modification to hypusine
xref
Reactome:REACT_99882 "Hypusine synthesis from eIF5A-lysine, Plasmodium falciparum"
xref
Reactome:REACT_114795 "Hypusine synthesis from eIF5A-lysine, Caenorhabditis elegans"
GO:0008624 : induction of apoptosis by extracellular signals
xref
Reactome:REACT_101011 "FASL binds FAS Receptor, Bos taurus"
xref
Reactome:REACT_113012 "Extrinsic Pathway for Apoptosis, Caenorhabditis elegans"
Reactome:REACT_113720 "FasL/ CD95L signaling, Xenopus tropicalis"
Reactome:REACT_114928 "Cell death signalling via NRAGE, NRIF and NADE, Dictyostelium discoideum"
Reactome:REACT_115331 "FASL binds FAS Receptor, Xenopus tropicalis"
Reactome:REACT_89305 "FASL binds FAS Receptor, Bos taurus"
GO:0008629 : induction of apoptosis by intracellular signals
xref
Reactome:REACT_113652 "Intrinsic Pathway for Apoptosis, Dictyostelium discoideum"
Reactome:REACT_113707 "Intrinsic Pathway for Apoptosis, Drosophila melanogaster"
Reactome:REACT_113789 "Intrinsic Pathway for Apoptosis, Oryza sativa"
Reactome:REACT_114288 "Intrinsic Pathway for Apoptosis, Arabidopsis thaliana"
Reactome:REACT_114326 "Intrinsic Pathway for Apoptosis, Schizosaccharomyces pombe"
Reactome:REACT_114572 "Intrinsic Pathway for Apoptosis, Saccharomyces cerevisiae"
GO:0008633 : activation of pro-apoptotic gene products
xref
Reactome:REACT_88970 "Activation of PUMA and translocation to mitochondria, Canis familiaris"
xref
Reactome:REACT_112012 "Activation of BIM and translocation to mitochondria, Xenopus tropicalis"
Reactome:REACT_112277 "Granzyme-B activates BID by cleavage, Xenopus tropicalis"
Reactome:REACT_112394 "Activation of NOXA and translocation to mitochondria, Canis familiaris"
Reactome:REACT_112824 "Caspase-8 is formed from procaspase-8, Caenorhabditis elegans"
Reactome:REACT_112867 "Activation of NOXA and translocation to mitochondria, Sus scrofa"
Reactome:REACT_113401 "Activation of NOXA and translocation to mitochondria, Rattus norvegicus"
Reactome:REACT_115069 "Activation of BAD and translocation to mitochondria, Xenopus tropicalis"
Reactome:REACT_115317 "Activation of NOXA and translocation to mitochondria, Mus musculus"
GO:0008635 : activation of caspase activity by cytochrome c
xref
Reactome:REACT_111966 "Activation of caspases through apoptosome-mediated cleavage, Bos taurus"
Reactome:REACT_113336 "Activation of caspases through apoptosome-mediated cleavage, Rattus norvegicus"
Reactome:REACT_114180 "Activation of caspases through apoptosome-mediated cleavage, Canis familiaris"
Reactome:REACT_114234 "Activation of caspases through apoptosome-mediated cleavage, Sus scrofa"
GO:0008645 : hexose transport
xref
Reactome:REACT_106522 "Hexose transport, Sus scrofa"
xref
Reactome:REACT_112026 "Hexose transport, Dictyostelium discoideum"
Reactome:REACT_112310 "Hexose transport, Mycobacterium tuberculosis"
Reactome:REACT_77191 "Hexose transport, Sus scrofa"
GO:0008652 : cellular amino acid biosynthetic process
xref
Reactome:REACT_104217 "Amino acid synthesis and interconversion (transamination), Sus scrofa"
xref
Reactome:REACT_112051 "Amino acid synthesis and interconversion (transamination), Staphylococcus aureus N315"
Reactome:REACT_31295 "Amino acid synthesis and interconversion (transamination), Sus scrofa"
GO:0008725 : DNA-3-methyladenine glycosylase activity
name
DNA-3-methyladenine glycosylase I activity
def
Catalysis of the hydrolysis of alkylated DNA; only recognizes and removes the alkylated base 3-methyladenine by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site.
is_a
GO:0003905
name
DNA-3-methyladenine glycosylase activity
def
Catalysis of the reaction: DNA containing 3-methyladenine + H2O = DNA with abasic site + 3-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methyladenine and the deoxyribose sugar to remove the 3-methyladenine, leaving an abasic site.
synonym
"DNA-3-methyladenine glycosylase I activity" EXACT []
xref
EC:3.2.2.21
MetaCyc:3.2.2.21-RXN
is_a
GO:0043733
GO:0008756 : o-succinylbenzoate-CoA ligase activity
synonym
"osb-CoA synthetase activity" EXACT [EC:6.2.1.26]
GO:0008783 : agmatinase activity
xref
Reactome:REACT_102547 "Agmatine + H2O <=> putrescine + urea, Staphylococcus aureus N315"
Reactome:REACT_108668 "Agmatine + H2O <=> putrescine + urea, Arabidopsis thaliana"
Reactome:REACT_86058 "Agmatine + H2O <=> putrescine + urea, Oryza sativa"
GO:0008792 : arginine decarboxylase activity
xref
Reactome:REACT_84356 "Arginine<=>Agmatine+CO2, Saccharomyces cerevisiae"
xref
Reactome:REACT_112250 "Arginine<=>Agmatine+CO2, Staphylococcus aureus N315"
Reactome:REACT_115439 "Arginine<=>Agmatine+CO2, Drosophila melanogaster"
Reactome:REACT_29623 "Arginine<=>Agmatine+CO2, Saccharomyces cerevisiae"
GO:0008802 : betaine-aldehyde dehydrogenase activity
is_a
GO:0016620
is_a
GO:0004029
GO:0008810 : cellulase activity
def
Catalysis of the endohydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
def
Catalysis of the endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
GO:0008815 : citrate (pro-3S)-lyase activity
xref
Reactome:REACT_81700 "Generation of Cytoplasmic Acetyl CoA from Citrate, Mycobacterium tuberculosis"
xref
Reactome:REACT_114344 "Generation of Cytoplasmic Acetyl CoA from Citrate, Saccharomyces cerevisiae"
Reactome:REACT_114419 "Generation of Cytoplasmic Acetyl CoA from Citrate, Caenorhabditis elegans"
GO:0008843 : endochitinase activity
def
Catalysis of the hydrolysis of nonterminal 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, endochitinases cleave randomly within the chitin chain.
def
Catalysis of the hydrolysis of nonterminal (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, endochitinases cleave randomly within the chitin chain.
GO:0008891 : glycolate oxidase activity
xref
Reactome:REACT_112171 "glycolate + O2 => glyoxylate + H2O2, Mycobacterium tuberculosis"
Reactome:REACT_112286 "glycolate + O2 => glyoxylate + H2O2, Oryza sativa"
Reactome:REACT_112704 "glycolate + O2 => glyoxylate + H2O2, Dictyostelium discoideum"
Reactome:REACT_113493 "glycolate + O2 => glyoxylate + H2O2, Escherichia coli"
Reactome:REACT_113804 "glycolate + O2 => glyoxylate + H2O2, Arabidopsis thaliana"
Reactome:REACT_114154 "glycolate + O2 => glyoxylate + H2O2, Drosophila melanogaster"
GO:0008897 : holo-[acyl-carrier-protein] synthase activity
xref
Reactome:REACT_114029 "Phosphopantetheine conjugation of the ACP domain of FAS, Dictyostelium discoideum"
Reactome:REACT_114181 "Phosphopantetheine conjugation of the ACP domain of FAS, Xenopus tropicalis"
GO:0008900 : hydrogen:potassium-exchanging ATPase activity
synonym
"h+/K+-exchanging ATPase activity" EXACT [EC:3.6.3.10]
GO:0008911 : lactaldehyde dehydrogenase activity
is_a
GO:0016620
is_a
GO:0004029
GO:0008932 : lytic endotransglycosylase activity
def
Catalysis of the specific cleavage of the beta-1,4 glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues. Acts on linkages within peptidoglycan chains (i.e. not at the ends) to produce shorter strands with 1,6-anhydromuramic acid ends.
def
Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues. Acts on linkages within peptidoglycan chains (i.e. not at the ends) to produce shorter strands with 1,6-anhydromuramic acid ends.
GO:0008933 : lytic transglycosylase activity
def
Catalysis of the specific cleavage of the beta-1,4 glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues.
def
Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues.
GO:0008936 : nicotinamidase activity
synonym
"namase activity" EXACT [EC:3.5.1.19]
GO:0008957 : phenylacetaldehyde dehydrogenase activity
is_a
GO:0016620
is_a
GO:0004029
GO:0009021 : tRNA (uracil-5-)-methyltransferase activity
synonym
"m5U-methyltransferase activity" EXACT [EC:2.1.1.35]
GO:0009044 : xylan 1,4-beta-xylosidase activity
def
Catalysis of the hydrolysis of 1,4-beta-D-xylans so as to remove successive D-xylose residues from the non-reducing termini.
def
Catalysis of the hydrolysis of (1->4)-beta-D-xylans so as to remove successive D-xylose residues from the non-reducing termini.
GO:0009055 : electron carrier activity
xref
Reactome:REACT_93247 "Reducing equivalents from beta-oxidation of fatty acids transfer to ETF, Saccharomyces cerevisiae"
xref
Reactome:REACT_108215 "Reducing equivalents from beta-oxidation of fatty acids transfer to ETF, Saccharomyces cerevisiae"
GO:0009083 : branched chain family amino acid catabolic process
xref
Reactome:REACT_89466 "Branched-chain amino acid catabolism, Sus scrofa"
xref
Reactome:REACT_98686 "Branched-chain amino acid catabolism, Sus scrofa"
GO:0009108 : coenzyme biosynthetic process
xref
Reactome:REACT_92003 "Coenzyme A biosynthesis, Caenorhabditis elegans"
xref
Reactome:REACT_107153 "Coenzyme A biosynthesis, Caenorhabditis elegans"
GO:0009168 : purine ribonucleoside monophosphate biosynthetic process
xref
Reactome:REACT_102227 "Purine ribonucleoside monophosphate biosynthesis, Sus scrofa"
Reactome:REACT_97778 "Purine ribonucleoside monophosphate biosynthesis, Schizosaccharomyces pombe"
xref
Reactome:REACT_33659 "Purine ribonucleoside monophosphate biosynthesis, Sus scrofa"
Reactome:REACT_92811 "Purine ribonucleoside monophosphate biosynthesis, Schizosaccharomyces pombe"
GO:0009692 : ethylene metabolic process
xref
Reactome:REACT_112653 "Ethylene is oxidized to Ethylene oxide by CYP1A1, Gallus gallus"
Reactome:REACT_113841 "Ethylene is oxidized to Ethylene oxide by CYP1A1, Danio rerio"
GO:0009804 : coumarin metabolic process
xref
Reactome:REACT_108785 "Coumarin is 7-hydroxylated by CYP2A13, Sus scrofa"
Reactome:REACT_88845 "Coumarin is 7-hydroxylated by CYP2A13, Canis familiaris"
xref
Reactome:REACT_112622 "Coumarin is 7-hydroxylated by CYP2A6, Xenopus tropicalis"
Reactome:REACT_112822 "Coumarin is 7-hydroxylated by CYP2A6, Danio rerio"
Reactome:REACT_113359 "Coumarin is 7-hydroxylated by CYP2A6, Mus musculus"
Reactome:REACT_113450 "Coumarin is 7-hydroxylated by CYP2A6, Rattus norvegicus"
GO:0009969 : xyloglucan biosynthetic process
def
The chemical reactions and pathways resulting in the formation of xyloglucan, the cross-linking glycan composed of 1->4-beta-D glucan backbone substituted at regular intervals with beta-D-xylosyl-1->6 residues, which is present in the primary cell wall of most higher plants.
def
The chemical reactions and pathways resulting in the formation of xyloglucan, the cross-linking glycan composed of (1->4)-beta-D glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants.
GO:0010021 : amylopectin biosynthetic process
def
The chemical reactions and pathways resulting in the formation of amylopectin, the (1,4) linked alpha glucose units with alpha-(1,6) linkages.
def
The chemical reactions and pathways resulting in the formation of amylopectin, the (1->4) linked alpha glucose units with alpha-(1->6) linkages.
GO:0010289 : homogalacturonan biosynthetic process
def
The chemical reactions and pathways resulting in the formation of the pectidic homogalacturonan, characterized by a backbone of 1,4-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.
def
The chemical reactions and pathways resulting in the formation of the pectidic homogalacturonan, characterized by a backbone of (1->4)-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.
GO:0010397 : apiogalacturonan metabolic process
def
The chemical reactions and pathways involving the pectic apiogalacturonan, characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted with apiose and apiobiose (D-apiofuranosyl-beta-(l->3)-D-apiose) side chains via O-2 or O-3 links.
def
The chemical reactions and pathways involving the pectic apiogalacturonan, characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted with apiose and apiobiose (D-apiofuranosyl-beta-(1->3)-D-apiose) side chains via O-2 or O-3 links.
GO:0010402 : pectic arabinan metabolic process
def
The chemical reactions and pathways involving arabinan, a polymer with an alpha-(1->5)-linked -L-arabinofuranose (Araf) backbone that can be substituted with Araf-alpha-(1->2)-, Araf-alpha-(1->3)-, and/or Araf-alpha-(1->3)-Araf-alpha-(1->3)-side chains. Arabinan can be found as a side chain of the pectin rhamnogalacturonan I.
def
The chemical reactions and pathways involving arabinan, a polymer with an alpha-(1->5)-linked L-arabinofuranose (Araf) backbone that can be substituted with Araf-alpha-(1->2)-, Araf-alpha-(1->3)-, and/or Araf-alpha-(1->3)-Araf-alpha-(1->3)-side chains. Arabinan can be found as a side chain of the pectin rhamnogalacturonan I.
GO:0010403 : pectic arabinogalactan I metabolic process
def
The chemical reactions and pathways involving pectic arabinogalactan I, an alpha-(1->4)-linked D-galactopyranose backbone that is substituted with alpha-l-Araf residues via the O-3 of the D-galactose residues. Arabinogalactan I can be found as a side chain of rhamnogalacturonan I.
def
The chemical reactions and pathways involving pectic arabinogalactan I, an alpha-(1,4)-linked D-galactopyranose backbone that is substituted with alpha-l-Araf residues via the O-3 of the D-galactose residues. Arabinogalactan I can be found as a side chain of rhamnogalacturonan I.
GO:0010465 : nerve growth factor receptor activity
relationship
has_part GO:0048406
GO:0010467 : gene expression
xref
Reactome:REACT_30701 "Gene Expression, Sus scrofa"
xref
Reactome:REACT_101952 "Gene Expression, Sus scrofa"
GO:0010493 : Lewis a epitope biosynthetic process
def
The chemical reactions and pathways resulting in the formation of a Lewis a epitope, a trisaccharide (Fuc-alpha-1->4(Gal-beta-1->3)GlcNAc) characteristic of plant protein N-linked oligosaccharides.
def
The chemical reactions and pathways resulting in the formation of a Lewis a epitope, a trisaccharide (Fuc-alpha-(1->4)[Gal-beta-(1->3)]GlcNAc) characteristic of plant protein N-linked oligosaccharides.
GO:0010510 : regulation of acetyl-CoA biosynthetic process from pyruvate
xref
Reactome:REACT_28764 "Regulation of pyruvate dehydrogenase (PDH) complex, Schizosaccharomyces pombe"
GO:0010706 : biosynthesis of lactosylceramide precursor to ganglioside
def
The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal beta(1,4)Glc beta(1,1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group as a precursor of gangliosides.
def
The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group as a precursor of gangliosides.
GO:0010707 : biosynthesis of lactosylceramide precursor to globoside
def
The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal beta(1,4)Glc beta(1,1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group as a precursor of globosides.
def
The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group as a precursor of globosides.
GO:0010827 : regulation of glucose transport
xref
Reactome:REACT_102535 "Regulation of Glucokinase by Glucokinase Regulatory Protein, Plasmodium falciparum"
Reactome:REACT_80959 "Regulation of Glucokinase by Glucokinase Regulatory Protein, Drosophila melanogaster"
xref
Reactome:REACT_100137 "Regulation of Glucokinase by Glucokinase Regulatory Protein, Plasmodium falciparum"
GO:0010843 : promoter binding
consider
GO:0001047
GO:0010908 : regulation of heparan sulfate proteoglycan biosynthetic process
def
Any process that modulates the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating (alpha1->4)-linked hexuronic acid and glucosamine residues.
def
Any process that modulates the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues.
GO:0010909 : positive regulation of heparan sulfate proteoglycan biosynthetic process
def
Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating (alpha1->4)-linked hexuronic acid and glucosamine residues.
def
Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues.
GO:0014047 : glutamate secretion
xref
Reactome:REACT_80086 "Glutamate Neurotransmitter Release Cycle, Sus scrofa"
xref
Reactome:REACT_112750 "Glutamate Neurotransmitter Release Cycle, Staphylococcus aureus N315"
Reactome:REACT_94050 "Glutamate Neurotransmitter Release Cycle, Sus scrofa"
GO:0015012 : heparan sulfate proteoglycan biosynthetic process
def
The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating (alpha1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues.
def
The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues.
GO:0015020 : glucuronosyltransferase activity
synonym
"Phenyl-UDP-glucuronosyltransferase activity" NARROW [EC:2.4.1.17]
xref
Reactome:REACT_109506 "bilirubin monoglucuronide + UDP-glucuronic acid => bilirubin diglucuronide + UDP, Xenopus tropicalis"
Reactome:REACT_30191 "Formation of O-glucuronides, Canis familiaris"
Reactome:REACT_30608 "bilirubin monoglucuronide + UDP-glucuronic acid => bilirubin diglucuronide + UDP, Gallus gallus"
Reactome:REACT_32163 "Formation of O-glucuronides, Drosophila melanogaster"
Reactome:REACT_32188 "bilirubin monoglucuronide + UDP-glucuronic acid => bilirubin diglucuronide + UDP, Sus scrofa"
Reactome:REACT_79398 "Formation of N-glucuronides, Xenopus tropicalis"
Reactome:REACT_80212 "Formation of N-glucuronides, Drosophila melanogaster"
Reactome:REACT_82301 "Formation of N-glucuronides, Gallus gallus"
Reactome:REACT_85610 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Gallus gallus"
Reactome:REACT_93560 "Formation of O-glucuronides, Xenopus tropicalis"
Reactome:REACT_93792 "Formation of O-glucuronides, Gallus gallus"
Reactome:REACT_94147 "bilirubin monoglucuronide + UDP-glucuronic acid => bilirubin diglucuronide + UDP, Drosophila melanogaster"
Reactome:REACT_94974 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Drosophila melanogaster"
Reactome:REACT_96026 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Xenopus tropicalis"
Reactome:REACT_96677 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Sus scrofa"
xref
Reactome:REACT_112395 "Formation of O-glucuronides, Caenorhabditis elegans"
Reactome:REACT_113946 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Caenorhabditis elegans"
Reactome:REACT_114051 "Formation of N-glucuronides, Caenorhabditis elegans"
Reactome:REACT_114908 "bilirubin monoglucuronide + UDP-glucuronic acid => bilirubin diglucuronide + UDP, Caenorhabditis elegans"
Reactome:REACT_96239 "bilirubin + UDP-glucuronic acid => bilirubin monoglucuronide + UDP, Sus scrofa"
Reactome:REACT_96318 "bilirubin monoglucuronide + UDP-glucuronic acid => bilirubin diglucuronide + UDP, Sus scrofa"
GO:0015038 : glutathione disulfide oxidoreductase activity
xref
Reactome:REACT_106063 "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized), Saccharomyces cerevisiae"
Reactome:REACT_106153 "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized), Caenorhabditis elegans"
Reactome:REACT_89210 "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized), Schizosaccharomyces pombe"
xref
Reactome:REACT_112460 "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized), Arabidopsis thaliana"
Reactome:REACT_114108 "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized), Oryza sativa"
Reactome:REACT_114787 "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized), Plasmodium falciparum"
Reactome:REACT_31672 "glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized), Caenorhabditis elegans"
GO:0015078 : hydrogen ion transmembrane transporter activity
xref
Reactome:REACT_102259 "Enzyme-bound ATP is released, Taeniopygia guttata"
GO:0015116 : sulfate transmembrane transporter activity
xref
Reactome:REACT_113041 "Group 1 - Sulphate transport, Plasmodium falciparum"
Reactome:REACT_113869 "Group 1 - Sulphate transport, Dictyostelium discoideum"
GO:0015125 : bile acid transmembrane transporter activity
xref
Reactome:REACT_51328 "Transport (influx) of glycocholate and taurocholate by OATP-C, Gallus gallus"
Reactome:REACT_82161 "Transport (influx) of glycocholate and taurocholate by OATP-8, Gallus gallus"
Reactome:REACT_87325 "Transport (influx) of bile salts and acids by OATP-A, Gallus gallus"
xref
Reactome:REACT_113507 "Transport (influx) of bile salts and acids by OATP-A, Danio rerio"
Reactome:REACT_114243 "Transport (influx) of glycocholate and taurocholate by OATP-C, Danio rerio"
Reactome:REACT_114986 "Transport (influx) of glycocholate and taurocholate by OATP-8, Danio rerio"
GO:0015129 : lactate transmembrane transporter activity
xref
Reactome:REACT_34617 "lactate + H+ [cytosol] <=> lactate + H+ [extracellular], Bos taurus"
Reactome:REACT_94399 "lactate + H+ [extracellular] <=> lactate + H+ [cytosol], Bos taurus"
xref
Reactome:REACT_101266 "lactate + H+ [cytosol] <=> lactate + H+ [extracellular], Bos taurus"
Reactome:REACT_112882 "lactate + H+ [cytosol] <=> lactate + H+ [extracellular], Drosophila melanogaster"
Reactome:REACT_113117 "lactate + H+ [extracellular] <=> lactate + H+ [cytosol], Drosophila melanogaster"
Reactome:REACT_94824 "lactate + H+ [extracellular] <=> lactate + H+ [cytosol], Bos taurus"
GO:0015149 : hexose transmembrane transporter activity
xref
Reactome:REACT_112037 "Transport (efflux) of fructose, galactose, and glucose by GLUT2, Dictyostelium discoideum"
Reactome:REACT_112649 "Transport (efflux) of fructose, galactose, and glucose by GLUT2, Caenorhabditis elegans"
Reactome:REACT_112973 "Transport (efflux) of fructose, galactose, and glucose by GLUT2, Arabidopsis thaliana"
Reactome:REACT_113207 "Transport (efflux) of fructose, galactose, and glucose by GLUT2, Drosophila melanogaster"
Reactome:REACT_114648 "Transport (efflux) of fructose, galactose, and glucose by GLUT2, Oryza sativa"
Reactome:REACT_114686 "Transport (efflux) of fructose, galactose, and glucose by GLUT2, Mycobacterium tuberculosis"
Reactome:REACT_115118 "Transport (efflux) of fructose, galactose, and glucose by GLUT2, Plasmodium falciparum"
GO:0015166 : polyol transmembrane transporter activity
xref
Reactome:REACT_112673 "Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6, Sus scrofa"
GO:0015171 : amino acid transmembrane transporter activity
xref
Reactome:REACT_100089 "SLC7A8-mediated uptake of neutral amino acids, Caenorhabditis elegans"
Reactome:REACT_100518 "SLC7A9-mediated exchange of extracellular arginine, lysine, or cystine for cytosolic leucine, Staphylococcus aureus N315"
Reactome:REACT_101173 "SLC6A14-mediated uptake of basic and neutral amino acids and of beta-alanine, Staphylococcus aureus N315"
Reactome:REACT_106510 "SLC38A1 (ATA1)-mediated uptake of neutral amino acids, Sus scrofa"
Reactome:REACT_108146 "SLC7A7 (y+LAT1)-mediated exchange of extracellular leucine for cytosolic arginine, Bos taurus"
Reactome:REACT_33631 "SLC7A7 (y+LAT1)-mediated exchange of extracellular leucine for cytosolic arginine, Drosophila melanogaster"
Reactome:REACT_79511 "SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine, Bos taurus"
Reactome:REACT_85083 "SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine, Danio rerio"
Reactome:REACT_91747 "SLC7A7 (y+LAT1)-mediated exchange of extracellular leucine for cytosolic arginine, Danio rerio"
Reactome:REACT_95711 "SLC7A9-mediated exchange of extracellular arginine, lysine, or cystine for cytosolic leucine, Bos taurus"
Reactome:REACT_96352 "SLC7A10-mediated uptake of small neutral amino acids, Caenorhabditis elegans"
xref
Reactome:REACT_112236 "SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane, Staphylococcus aureus N315"
Reactome:REACT_112274 "SLC7A3 (CAT-3)-mediated uptake of cationic amino acids, Dictyostelium discoideum"
Reactome:REACT_112402 "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine, Danio rerio"
Reactome:REACT_112436 "SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane, Staphylococcus aureus N315"
Reactome:REACT_112482 "L-Glutamate uptake by neurons, Staphylococcus aureus N315"
Reactome:REACT_112624 "SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids, Mycobacterium tuberculosis"
Reactome:REACT_112776 "SLC7A3 (CAT-3)-mediated uptake of cationic amino acids, Mycobacterium tuberculosis"
Reactome:REACT_112929 "SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids, Dictyostelium discoideum"
Reactome:REACT_112963 "L-Glutamate uptake by neurons, Caenorhabditis elegans"
Reactome:REACT_113003 "SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids, Staphylococcus aureus N315"
Reactome:REACT_113011 "SLC7A5-mediated uptake of neutral amino acids, Drosophila melanogaster"
Reactome:REACT_113174 "SLC38A4 (ATA3)-mediated uptake of arginine and lysine, Xenopus tropicalis"
Reactome:REACT_113529 "SLC6A6-mediated uptake of taurine and beta-alanine, Staphylococcus aureus N315"
Reactome:REACT_113690 "SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids, Staphylococcus aureus N315"
Reactome:REACT_113752 "SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate, Caenorhabditis elegans"
Reactome:REACT_113768 "SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine, Staphylococcus aureus N315"
Reactome:REACT_114141 "SLC6A14-mediated uptake of basic and neutral amino acids and of beta-alanine, Drosophila melanogaster"
Reactome:REACT_114242 "SLC6A14-mediated uptake of basic and neutral amino acids and of beta-alanine, Danio rerio"
Reactome:REACT_114291 "SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine, Staphylococcus aureus N315"
Reactome:REACT_114502 "SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids, Mycobacterium tuberculosis"
Reactome:REACT_114685 "SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine, Staphylococcus aureus N315"
Reactome:REACT_114768 "SLC7A3 (CAT-3)-mediated uptake of cationic amino acids, Staphylococcus aureus N315"
Reactome:REACT_114801 "SLC43A1 (LAT3)-mediated uptake of large neutral amino acids, Dictyostelium discoideum"
Reactome:REACT_114819 "SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids, Dictyostelium discoideum"
Reactome:REACT_114980 "SLC7A9-mediated exchange of extracellular arginine, lysine, or cystine for cytosolic leucine, Sus scrofa"
Reactome:REACT_115089 "SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine, Staphylococcus aureus N315"
Reactome:REACT_115373 "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine, Staphylococcus aureus N315"
Reactome:REACT_115430 "SLC16A10-mediated uptake of aromatic amino acids, Saccharomyces cerevisiae"
Reactome:REACT_30219 "SLC38A1 (ATA1)-mediated uptake of neutral amino acids, Sus scrofa"
Reactome:REACT_34240 "SLC7A7 (y+LAT1)-mediated exchange of extracellular leucine for cytosolic arginine, Bos taurus"
Reactome:REACT_85083 "SLC7A7 (y+LAT1)-mediated exchange of extracellular leucine for cytosolic arginine, Danio rerio"
Reactome:REACT_89087 "SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine, Bos taurus"
Reactome:REACT_91835 "SLC7A9-mediated exchange of extracellular arginine, lysine, or cystine for cytosolic leucine, Bos taurus"
GO:0015172 : acidic amino acid transmembrane transporter activity
xref
Reactome:REACT_29456 "aspartate [mitochondrial matrix] + glutamate [cytosol] => aspartate [cytosol] + glutamate [mitochondrial matrix], Saccharomyces cerevisiae"
xref
Reactome:REACT_83233 "aspartate [mitochondrial matrix] + glutamate [cytosol] => aspartate [cytosol] + glutamate [mitochondrial matrix], Saccharomyces cerevisiae"
GO:0015207 : adenine transmembrane transporter activity
xref
Reactome:REACT_104265 "ADP-ATP translocase maintains a high ADP:ATP ratio in the matrix, Plasmodium falciparum"
Reactome:REACT_28807 "ADP-ATP translocase maintains a high ADP:ATP ratio in the matrix, Sus scrofa"
Reactome:REACT_29203 "ADP-ATP translocase maintains a high ADP:ATP ratio in the matrix, Bos taurus"
Reactome:REACT_87825 "ADP-ATP translocase maintains a high ADP:ATP ratio in the matrix, Caenorhabditis elegans"
xref
Reactome:REACT_106927 "ADP-ATP translocase maintains a high ADP:ATP ratio in the matrix, Sus scrofa"
Reactome:REACT_114818 "ADP-ATP translocase maintains a high ADP:ATP ratio in the matrix, Arabidopsis thaliana"
Reactome:REACT_115148 "ADP-ATP translocase maintains a high ADP:ATP ratio in the matrix, Oryza sativa"
Reactome:REACT_29736 "ADP-ATP translocase maintains a high ADP:ATP ratio in the matrix, Bos taurus"
GO:0015220 : choline transmembrane transporter activity
xref
Reactome:REACT_113748 "Sodium- and chloride-dependent choline transport by CHT, Staphylococcus aureus N315"
Reactome:REACT_115008 "Transport of Choline, Staphylococcus aureus N315"
GO:0015227 : acyl carnitine transporter activity
xref
Reactome:REACT_79062 "Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane, Caenorhabditis elegans"
xref
Reactome:REACT_112186 "Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane, Schizosaccharomyces pombe"
Reactome:REACT_90417 "Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane, Caenorhabditis elegans"
GO:0015232 : heme transporter activity
xref
Reactome:REACT_100385 "ABCB7-mediated transport, Dictyostelium discoideum"
Reactome:REACT_104882 "ABCB7-mediated transport, Oryza sativa"
Reactome:REACT_104909 "ABCB7-mediated transport, Schizosaccharomyces pombe"
Reactome:REACT_105656 "ABCB7-mediated transport, Taeniopygia guttata"
Reactome:REACT_106955 "ABCB7-mediated transport, Saccharomyces cerevisiae"
Reactome:REACT_109850 "ABCB7-mediated transport, Drosophila melanogaster"
Reactome:REACT_110140 "ABCB7-mediated transport, Danio rerio"
Reactome:REACT_22342 "ABCB7-mediated transport, Homo sapiens"
Reactome:REACT_29208 "ABCB7-mediated transport, Caenorhabditis elegans"
Reactome:REACT_34709 "ABCB7-mediated transport, Sus scrofa"
Reactome:REACT_77717 "ABCB7-mediated transport, Mus musculus"
Reactome:REACT_78473 "ABCB7-mediated transport, Canis familiaris"
Reactome:REACT_82495 "ABCB7-mediated transport, Arabidopsis thaliana"
Reactome:REACT_88411 "ABCB7-mediated transport, Bos taurus"
Reactome:REACT_94308 "ABCB7-mediated transport, Gallus gallus"
Reactome:REACT_97364 "ABCB7-mediated transport, Xenopus tropicalis"
Reactome:REACT_97806 "ABCB7-mediated transport, Rattus norvegicus"
xref
Reactome:REACT_100385 "ABC7, mABC1 and mABC2 mediate heme transport, Dictyostelium discoideum"
Reactome:REACT_104882 "ABC7, mABC1 and mABC2 mediate heme transport, Oryza sativa"
Reactome:REACT_104909 "ABC7, mABC1 and mABC2 mediate heme transport, Schizosaccharomyces pombe"
Reactome:REACT_105656 "ABC7, mABC1 and mABC2 mediate heme transport, Taeniopygia guttata"
Reactome:REACT_106955 "ABC7, mABC1 and mABC2 mediate heme transport, Saccharomyces cerevisiae"
Reactome:REACT_109850 "ABC7, mABC1 and mABC2 mediate heme transport, Drosophila melanogaster"
Reactome:REACT_110140 "ABC7, mABC1 and mABC2 mediate heme transport, Danio rerio"
Reactome:REACT_111156 "MTABC3 transports porphyrin into mitochondria, Homo sapiens"
Reactome:REACT_112680 "ABC7, mABC1 and mABC2 mediate heme transport, Mycobacterium tuberculosis"
Reactome:REACT_114177 "ABC7, mABC1 and mABC2 mediate heme transport, Staphylococcus aureus N315"
Reactome:REACT_114591 "ABC7, mABC1 and mABC2 mediate heme transport, Plasmodium falciparum"
Reactome:REACT_22342 "ABC7, mABC1 and mABC2 mediate heme transport, Homo sapiens"
Reactome:REACT_29208 "ABC7, mABC1 and mABC2 mediate heme transport, Caenorhabditis elegans"
Reactome:REACT_34709 "ABC7, mABC1 and mABC2 mediate heme transport, Sus scrofa"
Reactome:REACT_77717 "ABC7, mABC1 and mABC2 mediate heme transport, Mus musculus"
Reactome:REACT_78473 "ABC7, mABC1 and mABC2 mediate heme transport, Canis familiaris"
Reactome:REACT_82495 "ABC7, mABC1 and mABC2 mediate heme transport, Arabidopsis thaliana"
Reactome:REACT_88411 "ABC7, mABC1 and mABC2 mediate heme transport, Bos taurus"
Reactome:REACT_94308 "ABC7, mABC1 and mABC2 mediate heme transport, Gallus gallus"
Reactome:REACT_97364 "ABC7, mABC1 and mABC2 mediate heme transport, Xenopus tropicalis"
Reactome:REACT_97806 "ABC7, mABC1 and mABC2 mediate heme transport, Rattus norvegicus"
GO:0015248 : sterol transporter activity
xref
Reactome:REACT_107624 "ABCG5:ABCG8-mediated export of cholesterol and phytosterols, Arabidopsis thaliana"
Reactome:REACT_30246 "ABCG5:ABCG8-mediated export of cholesterol and phytosterols, Oryza sativa"
Reactome:REACT_97437 "ABCG5:ABCG8-mediated export of cholesterol and phytosterols, Dictyostelium discoideum"
xref
Reactome:REACT_113802 "ABCG5:ABCG8-mediated export of cholesterol and phytosterols, Saccharomyces cerevisiae"
Reactome:REACT_114568 "ABCG5:ABCG8-mediated export of cholesterol and phytosterols, Mycobacterium tuberculosis"
Reactome:REACT_114596 "ABCG5:ABCG8-mediated export of cholesterol and phytosterols, Drosophila melanogaster"
GO:0015250 : water channel activity
xref
Reactome:REACT_107896 "Passive Transport of Water out of Cell by Aquaporin-3, Caenorhabditis elegans"
GO:0015291 : secondary active transmembrane transporter activity
xref
Reactome:REACT_113603 "CoA transport across the inner mitochondrial membrane, Xenopus tropicalis"
Reactome:REACT_114125 "CoA transport across the inner mitochondrial membrane, Oryza sativa"
Reactome:REACT_114308 "CoA transport across the inner mitochondrial membrane, Arabidopsis thaliana"
GO:0015307 : drug:hydrogen antiporter activity
xref
Reactome:REACT_112833 "MATEs mediate extrusion of xenobiotics, Escherichia coli"
Reactome:REACT_113029 "MATEs mediate extrusion of xenobiotics, Schizosaccharomyces pombe"
Reactome:REACT_113149 "MATEs mediate extrusion of xenobiotics, Saccharomyces cerevisiae"
Reactome:REACT_113868 "MATEs mediate extrusion of xenobiotics, Oryza sativa"
Reactome:REACT_114597 "MATEs mediate extrusion of xenobiotics, Dictyostelium discoideum"
Reactome:REACT_114825 "MATEs mediate extrusion of xenobiotics, Arabidopsis thaliana"
GO:0015321 : sodium-dependent phosphate transmembrane transporter activity
xref
Reactome:REACT_104031 "Type III Na+/Pi cotransport, Caenorhabditis elegans"
Reactome:REACT_32338 "Electrogenic Na+/Pi cotransport, Caenorhabditis elegans"
Reactome:REACT_32759 "Electroneutral Na+/Pi cotransport, Danio rerio"
Reactome:REACT_83291 "Electroneutral Na+/Pi cotransport, Caenorhabditis elegans"
Reactome:REACT_84409 "Type I Na+-coupled phosphate co-transport, Dictyostelium discoideum"
Reactome:REACT_87531 "Type III Na+/Pi cotransport, Plasmodium falciparum"
xref
Reactome:REACT_112119 "Type I Na+-coupled phosphate co-transport, Oryza sativa"
Reactome:REACT_112519 "Electroneutral Na+/Pi cotransport, Escherichia coli"
Reactome:REACT_113455 "Electrogenic Na+/Pi cotransport, Escherichia coli"
Reactome:REACT_113983 "Type I Na+-coupled phosphate co-transport, Staphylococcus aureus N315"
Reactome:REACT_114049 "Type I Na+-coupled phosphate co-transport, Escherichia coli"
Reactome:REACT_114542 "Type I Na+-coupled phosphate co-transport, Arabidopsis thaliana"
Reactome:REACT_114838 "Type III Na+/Pi cotransport, Mycobacterium tuberculosis"
Reactome:REACT_115481 "Type I Na+-coupled phosphate co-transport, Caenorhabditis elegans"
Reactome:REACT_85878 "Type III Na+/Pi cotransport, Plasmodium falciparum"
GO:0015333 : peptide:hydrogen symporter activity
xref
Reactome:REACT_111949 "Proton-coupled histidine and di-peptide cotransport, Saccharomyces cerevisiae"
Reactome:REACT_114016 "Proton-coupled di- and tri-peptide cotransport, Caenorhabditis elegans"
Reactome:REACT_115385 "Proton-coupled histidine and di-peptide cotransport, Schizosaccharomyces pombe"
GO:0015367 : oxoglutarate:malate antiporter activity
xref
Reactome:REACT_30925 "malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix], Drosophila melanogaster"
xref
Reactome:REACT_112909 "malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix], Dictyostelium discoideum"
GO:0015368 : calcium:cation antiporter activity
xref
Reactome:REACT_112998 "K+-independent Li+/Ca2+ exchanger transport, Arabidopsis thaliana"
Reactome:REACT_114708 "K+-independent Li+/Ca2+ exchanger transport, Oryza sativa"
GO:0015378 : sodium:chloride symporter activity
xref
Reactome:REACT_113205 "Na+/Cl- cotransport, Drosophila melanogaster"
Reactome:REACT_114168 "Na+/Cl- cotransport, Caenorhabditis elegans"
GO:0015379 : potassium:chloride symporter activity
xref
Reactome:REACT_114447 "K+/Cl- cotransport, Caenorhabditis elegans"
GO:0015385 : sodium:hydrogen antiporter activity
xref
Reactome:REACT_112054 "Na+/H+ exchanger transport (at early endosome membrane), Gallus gallus"
GO:0015432 : bile acid-exporting ATPase activity
xref
Reactome:REACT_102709 "Transport (efflux) of bile salts by ABCC3 (MRP3), Gallus gallus"
Reactome:REACT_31005 "Transport (efflux) of bile salts by ABCC3 (MRP3), Xenopus tropicalis"
Reactome:REACT_77625 "Transport (efflux) of bile salts by ABCC3 (MRP3), Taeniopygia guttata"
Reactome:REACT_79348 "Transport (efflux) of bile salts by ABCC3 (MRP3), Canis familiaris"
Reactome:REACT_83682 "Transport (efflux) of bile salts by ABCC3 (MRP3), Bos taurus"
Reactome:REACT_87263 "Transport (efflux) of bile salts by ABCC3 (MRP3), Sus scrofa"
Reactome:REACT_93084 "Transport (efflux) of bile salts by ABCC3 (MRP3), Mus musculus"
Reactome:REACT_94139 "Transport (efflux) of bile salts by ABCC3 (MRP3), Rattus norvegicus"
xref
Reactome:REACT_112096 "Transport (efflux) of bile salts by ABCB11 (bile salt export pump), Plasmodium falciparum"
Reactome:REACT_112416 "Transport (efflux) of bile salts by ABCB11 (bile salt export pump), Dictyostelium discoideum"
Reactome:REACT_113803 "Transport (efflux) of bile salts by ABCB11 (bile salt export pump), Schizosaccharomyces pombe"
Reactome:REACT_113836 "Transport (efflux) of bile salts by ABCB11 (bile salt export pump), Arabidopsis thaliana"
Reactome:REACT_114961 "Transport (efflux) of bile salts by ABCB11 (bile salt export pump), Oryza sativa"
GO:0015433 : peptide antigen-transporting ATPase activity
xref
Reactome:REACT_111185 "Translocation of antigenic peptides back to phagosomes via TAP, Homo sapiens"
GO:0015444 : magnesium-importing ATPase activity
synonym
"mg2+-importing ATPase activity" EXACT [EC:3.6.3.2]
GO:0015464 : acetylcholine receptor activity
is_a
GO:0042166
relationship
has_part GO:0042166
GO:0015467 : G-protein activated inward rectifier potassium channel activity
xref
Reactome:REACT_90601 "Activation of GIRK/Kir3 Channels, Gallus gallus"
xref
Reactome:REACT_114055 "Activation of GIRK/Kir3 Channels, Xenopus tropicalis"
GO:0015538 : sialic acid:hydrogen symporter activity
xref
Reactome:REACT_92908 "Proton-coupled sialic acid co-transport, Dictyostelium discoideum"
xref
Reactome:REACT_112212 "Proton-coupled sialic acid co-transport, Escherichia coli"
Reactome:REACT_112268 "Proton-coupled sialic acid co-transport, Caenorhabditis elegans"
Reactome:REACT_113008 "Proton-coupled sialic acid co-transport, Xenopus tropicalis"
Reactome:REACT_113908 "Proton-coupled sialic acid co-transport, Arabidopsis thaliana"
Reactome:REACT_114194 "Proton-coupled sialic acid co-transport, Oryza sativa"
Reactome:REACT_114441 "Proton-coupled sialic acid co-transport, Staphylococcus aureus N315"
GO:0015662 : ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
xref
Reactome:REACT_104048 "ABCC4 accumulation of dense granule contents, Bos taurus"
Reactome:REACT_31429 "ABCC4 accumulation of dense granule contents, Taeniopygia guttata"
Reactome:REACT_78040 "ABCC4 accumulation of dense granule contents, Xenopus tropicalis"
Reactome:REACT_84400 "ABCC4 accumulation of dense granule contents, Rattus norvegicus"
Reactome:REACT_90831 "ABCC4 accumulation of dense granule contents, Canis familiaris"
Reactome:REACT_97312 "ABCC4 accumulation of dense granule contents, Sus scrofa"
GO:0015701 : bicarbonate transport
xref
Reactome:REACT_114123 "Bicarbonate transporters, Dictyostelium discoideum"
GO:0015721 : bile acid and bile salt transport
xref
Reactome:REACT_112634 "Recycling of bile acids and salts, Dictyostelium discoideum"
Reactome:REACT_113431 "Recycling of bile acids and salts, Plasmodium falciparum"
Reactome:REACT_113858 "Recycling of bile acids and salts, Saccharomyces cerevisiae"
Reactome:REACT_114004 "Recycling of bile acids and salts, Arabidopsis thaliana"
Reactome:REACT_114070 "Recycling of bile acids and salts, Oryza sativa"
Reactome:REACT_114193 "Recycling of bile acids and salts, Schizosaccharomyces pombe"
GO:0015758 : glucose transport
xref
Reactome:REACT_106224 "Glucose transport, Sus scrofa"
xref
Reactome:REACT_112521 "Glucose transport, Dictyostelium discoideum"
Reactome:REACT_114803 "Glucose transport, Mycobacterium tuberculosis"
Reactome:REACT_79237 "Glucose transport, Sus scrofa"
GO:0015918 : sterol transport
xref
Reactome:REACT_111982 "Trafficking of dietary sterols, Plasmodium falciparum"
Reactome:REACT_114213 "Trafficking of dietary sterols, Mycobacterium tuberculosis"
GO:0015939 : pantothenate metabolic process
xref
Reactome:REACT_56657 "Vitamin B5 (pantothenate) metabolism, Caenorhabditis elegans"
xref
Reactome:REACT_83248 "Vitamin B5 (pantothenate) metabolism, Caenorhabditis elegans"
GO:0015949 : nucleobase-containing small molecule interconversion
xref
Reactome:REACT_99115 "Synthesis and interconversion of nucleotide di- and triphosphates, Sus scrofa"
Reactome:REACT_99360 "Synthesis and interconversion of nucleotide di- and triphosphates, Staphylococcus aureus N315"
xref
Reactome:REACT_96776 "Synthesis and interconversion of nucleotide di- and triphosphates, Sus scrofa"
GO:0016019 : peptidoglycan receptor activity
is_a
GO:0042834
relationship
has_part GO:0042834
GO:0016153 : urocanate hydratase activity
xref
Reactome:REACT_95592 "urocanate + H2O => 4-imidazolone-5-propionate, Caenorhabditis elegans"
xref
Reactome:REACT_109123 "urocanate + H2O => 4-imidazolone-5-propionate, Caenorhabditis elegans"
GO:0016162 : cellulose 1,4-beta-cellobiosidase activity
def
Catalysis of the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains.
def
Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains.
GO:0016175 : superoxide-generating NADPH oxidase activity
xref
Reactome:REACT_111243 "Alkalization of the phagosomal lumen by NOX2, Homo sapiens"
Reactome:REACT_111249 "Uncoupled eNOS favours the formation of superoxide, Homo sapiens"
GO:0016232 : HNK-1 sulfotransferase activity
def
Catalysis of the synthesis of the HKK-1 carbohydrate epitope; adds a sulfate group to a precursor, GlcA-beta-(1,3)-Gal-beta-(1,4)-GlcNAc-beta-(1->R), forming sulfo-3GlcA-beta-(1,3)-Gal-beta-(1,4)-GlcNAc-beta-(1->R).
def
Catalysis of the synthesis of the HKK-1 carbohydrate epitope; adds a sulfate group to a precursor, GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R), forming sulfo-3GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R).
GO:0016233 : telomere capping
xref
Reactome:REACT_106265 "Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure, Gallus gallus"
Reactome:REACT_50133 "Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure, Gallus gallus"
xref
Reactome:REACT_112263 "Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure, Danio rerio"
Reactome:REACT_113641 "Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure, Canis familiaris"
Reactome:REACT_114938 "Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure, Danio rerio"
Reactome:REACT_115404 "Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure, Canis familiaris"
GO:0016255 : attachment of GPI anchor to protein
xref
Reactome:REACT_112166 "Attachment of GPI anchor to uPAR, Xenopus tropicalis"
GO:0016267 : O-glycan processing, core 1
def
The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 1 O-glycan structure, Gal-beta-1->3-GalNAc.
def
The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 1 O-glycan structure, Gal-beta-(1->3)-GalNAc.
GO:0016268 : O-glycan processing, core 2
def
The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 2 O-glycan structure, GlcNAc-beta-1->6(Gal-beta-1->3)-GalNAc.
def
The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 2 O-glycan structure, GlcNAc-beta-(1->6)[Gal-beta-(1->3)]-GalNAc.
GO:0016269 : O-glycan processing, core 3
def
The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 3 O-glycan structure, GlcNAc-beta-1->3-GalNAc.
def
The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 3 O-glycan structure, GlcNAc-beta-(1->3)-GalNAc.
GO:0016270 : O-glycan processing, core 4
def
The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 4 O-glycan structure, GlcNAc-beta-1->6(GlcNAc-beta-1->3)-GalNAc.
def
The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 4 O-glycan structure, GlcNAc-beta-(1->6)[GalNAc-beta-(1->3)]-GalNAc.
GO:0016274 : protein-arginine N-methyltransferase activity
xref
Reactome:REACT_112455 "Loading and methylation of Sm proteins onto SMN Complexes, Xenopus tropicalis"
GO:0016287 : glycerone-phosphate O-acyltransferase activity
xref
Reactome:REACT_114425 "palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH, Mycobacterium tuberculosis"
Reactome:REACT_114844 "palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH, Escherichia coli"
GO:0016290 : palmitoyl-CoA hydrolase activity
synonym
"long-chain fatty-acyl-CoA hydrolase activity" EXACT []
is_a
GO:0016291
synonym
"long-chain fatty-acyl-CoA hydrolase activity" BROAD []
is_a
GO:0047617
GO:0016298 : lipase activity
xref
Reactome:REACT_101475 "diacylglycerol + H2O -> 2-acylglycerol + fatty acid, Drosophila melanogaster"
Reactome:REACT_108697 "cholesterol ester + H2O -> cholesterol + fatty acid, Drosophila melanogaster"
Reactome:REACT_93242 "cholesterol ester + H2O -> cholesterol + fatty acid, Bos taurus"
xref
Reactome:REACT_112065 "diacylglycerol + H2O -> 2-acylglycerol + fatty acid, Danio rerio"
Reactome:REACT_114396 "cholesterol ester + H2O -> cholesterol + fatty acid, Danio rerio"
Reactome:REACT_90239 "cholesterol ester + H2O -> cholesterol + fatty acid, Bos taurus"
GO:0016301 : kinase activity
xref
Reactome:REACT_100400 "CAK-mediated phosphorylation of Cyclin E:Cdk2, Bos taurus"
Reactome:REACT_100988 "Phosphorylation of histone H2AX at Serine-139 by ATM at the site of DSB, Saccharomyces cerevisiae"
Reactome:REACT_101802 "Phosphorylation of MDM2 at serine-395 by ATM kinase, Sus scrofa"
Reactome:REACT_102691 "CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes, Bos taurus"
Reactome:REACT_105360 "Activation of the Anaphase Promoting Complex (APC) by Plk1, Saccharomyces cerevisiae"
Reactome:REACT_105371 "Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3, Danio rerio"
Reactome:REACT_105836 "Phosphorylation of 4E-BP1 by activated mTORC1, Rattus norvegicus"
Reactome:REACT_106651 "CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes, Sus scrofa"
Reactome:REACT_108365 "Phosphorylation of histone H2AX at Serine-139 by ATM at the site of DSB, Arabidopsis thaliana"
Reactome:REACT_109807 "Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3, Caenorhabditis elegans"
Reactome:REACT_110063 "Phosphorylation and activation of eIF4G by activated S6K1, Bos taurus"
Reactome:REACT_110996 "CAK-mediated phosphorylation of Cyclin A:Cdk2, Bos taurus"
Reactome:REACT_28667 "Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3, Sus scrofa"
Reactome:REACT_30381 "Phosphorylation of beta-catenin at Ser45 by CK1 alpha, Danio rerio"
Reactome:REACT_31035 "Phosphorylation and inactivation of eEF2K by activated S6K1, Sus scrofa"
Reactome:REACT_31296 "Phosphoryation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3, Caenorhabditis elegans"
Reactome:REACT_31799 "Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3, Caenorhabditis elegans"
Reactome:REACT_33110 "Phosphorylation (Ser5) of RNA pol II CTD, Schizosaccharomyces pombe"
Reactome:REACT_63920 "SOS phosphorylation and dissociation (IRS), Bos taurus"
Reactome:REACT_77104 "Phosphorylation of beta-catenin at Ser45 by CK1 alpha, Sus scrofa"
Reactome:REACT_78012 "Phosphoryation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3, Danio rerio"
Reactome:REACT_78393 "Phosphorylation of Cyclin B1 in the CRS domain, Caenorhabditis elegans"
Reactome:REACT_79233 "Phosphorylation of histone H2AX at Serine-139 by ATM at the site of DSB, Oryza sativa"
Reactome:REACT_79440 "Activation of the Anaphase Promoting Complex (APC) by Plk1, Dictyostelium discoideum"
Reactome:REACT_79451 "Activation of S6K1, Rattus norvegicus"
Reactome:REACT_79478 "Phosphorylation (Ser5) of RNA pol II CTD, Bos taurus"
Reactome:REACT_80111 "Cdc6 protein is phosphorylated by CDK, Sus scrofa"
Reactome:REACT_80177 "CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes, Caenorhabditis elegans"
Reactome:REACT_80221 "Intermolecular autophosphorylation of ATM within dimeric ATM complexes, Caenorhabditis elegans"
Reactome:REACT_80679 "Phosphorylation and activation of Chk1 by ATM, Caenorhabditis elegans"
Reactome:REACT_81185 "Phosphorylation and activation of Chk1 by ATM, Schizosaccharomyces pombe"
Reactome:REACT_81253 "Inactivation of Myt1 kinase, Saccharomyces cerevisiae"
Reactome:REACT_81838 "Phosphorylation of AKT2 by PDK1, Dictyostelium discoideum"
Reactome:REACT_82555 "Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3, Danio rerio"
Reactome:REACT_82583 "SOS phosphorylation and dissociation (SHC), Bos taurus"
Reactome:REACT_82945 "Phosphorylation of Cdc25C at Ser216, Danio rerio"
Reactome:REACT_82955 "Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes, Sus scrofa"
Reactome:REACT_83381 "Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3, Sus scrofa"
Reactome:REACT_83893 "Phosphorylation of histone H2AX at Serine-139 by ATM at the site of DSB, Xenopus tropicalis"
Reactome:REACT_84361 "Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197, Dictyostelium discoideum"
Reactome:REACT_85274 "Activation of Cdc25C, Danio rerio"
Reactome:REACT_85906 "Phosphorylation of Cyclin D:Cdk4/6 complexes, Bos taurus"
Reactome:REACT_86472 "Phosphorylation of APC component of the destruction complex, Danio rerio"
Reactome:REACT_87470 "Phosphorylation of beta-catenin at Ser45 by CK1 alpha, Caenorhabditis elegans"
Reactome:REACT_88476 "Phosphorylation of histone H2AX at Serine-139 by ATM at the site of DSB, Schizosaccharomyces pombe"
Reactome:REACT_89430 "CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes, Bos taurus"
Reactome:REACT_89572 "Phosphorylation of histone H2AX at Serine-139 by ATM at the site of DSB, Drosophila melanogaster"
Reactome:REACT_90760 "Phosphorylation of APC component of the destruction complex, Caenorhabditis elegans"
Reactome:REACT_91575 "Phosphorylation of L1 by ERK, Schizosaccharomyces pombe"
Reactome:REACT_91734 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Bos taurus"
Reactome:REACT_92084 "Phosphoryation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3, Sus scrofa"
Reactome:REACT_92398 "Phosphorylation of PDE3B, Sus scrofa"
Reactome:REACT_92944 "Autophosphorylation of PAK-2p34 in the activation loop, Dictyostelium discoideum"
Reactome:REACT_93474 "Phosphorylation of Cdc25A at Ser-123 by Chk2, Dictyostelium discoideum"
Reactome:REACT_94350 "Phosphorylation of DLC1 by MAPK 8, Mus musculus"
Reactome:REACT_94361 "Phosphorylation and activation of CHK2 by ATM, Caenorhabditis elegans"
Reactome:REACT_94648 "Regulation of NudC by phosphorylation, Schizosaccharomyces pombe"
Reactome:REACT_96123 "Phosphorylation and activation of eIF4B by activated S6K1, Rattus norvegicus"
Reactome:REACT_96416 "Activation of Cdc25C, Dictyostelium discoideum"
Reactome:REACT_96493 "Phosphorylation (Ser5) of RNA pol II CTD, Canis familiaris"
Reactome:REACT_97280 "Phosphorylation of Cdc25A at Ser-123 in response to DNA damage, Dictyostelium discoideum"
Reactome:REACT_97613 "Phosphorylation of APC component of the destruction complex, Sus scrofa"
xref
Reactome:REACT_110296 "Phosphorylation and activation of Chk1 by ATM, Schizosaccharomyces pombe"
Reactome:REACT_111124 "FGFR associated PI3K phosphorylates PIP2 to PIP3, Homo sapiens"
Reactome:REACT_111171 "FGFR-associated PI3K phosphorylates PIP2 to PIP3, Homo sapiens"
Reactome:REACT_111930 "Phosphorylation of Cdc25A at Ser-123 by Chk2, Caenorhabditis elegans"
Reactome:REACT_112075 "Mcm2-7 is phosphorylated by DDK, Drosophila melanogaster"
Reactome:REACT_112101 "Phosphorylation of L1 by CK-II, Xenopus tropicalis"
Reactome:REACT_112156 "Phosphorylation of AKT2 by PDK1, Saccharomyces cerevisiae"
Reactome:REACT_112214 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Schizosaccharomyces pombe"
Reactome:REACT_112270 "Akt1 phosphorylates BAD protein, Xenopus tropicalis"
Reactome:REACT_112298 "Autophosphorylation of DNA-PKcs, Dictyostelium discoideum"
Reactome:REACT_112324 "Phosphorylation and activation of eIF4G by activated S6K1, Oryza sativa"
Reactome:REACT_112360 "Regulation of MKLP-1 by phosphorylation, Dictyostelium discoideum"
Reactome:REACT_112413 "Phosphorylation of Cdc25A at Ser-123 by Chk2, Saccharomyces cerevisiae"
Reactome:REACT_112480 "Inactivation of Wee1 kinase, Dictyostelium discoideum"
Reactome:REACT_112545 "Phosphorylation and activation of eIF4G by activated S6K1, Drosophila melanogaster"
Reactome:REACT_112633 "CAK-mediated phosphorylation of Cyclin E:Cdk2, Saccharomyces cerevisiae"
Reactome:REACT_112709 "Phosphorylation of L1 by ERK, Saccharomyces cerevisiae"
Reactome:REACT_112722 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Drosophila melanogaster"
Reactome:REACT_112790 "Phosphorylation of Cdc25A at Ser-123 in response to DNA damage, Caenorhabditis elegans"
Reactome:REACT_112846 "Phosphorylation of Cyclin E1:Cdk2 complexes by Myt1, Saccharomyces cerevisiae"
Reactome:REACT_112892 "Phosphorylation of BRCA1 at multiple sites by ATM, Oryza sativa"
Reactome:REACT_112948 "Autophosphorylation of DNA-PKcs, Rattus norvegicus"
Reactome:REACT_113022 "Phosphorylation of Cyclin B1 in the CRS domain, Schizosaccharomyces pombe"
Reactome:REACT_113051 "Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta, Arabidopsis thaliana"
Reactome:REACT_113121 "Phosphorylation and activation of eIF4B by activated S6K1, Schizosaccharomyces pombe"
Reactome:REACT_113227 "Phosphorylation of Ribosomal protein S6 by activated S6K1, Saccharomyces cerevisiae"
Reactome:REACT_113244 "CAK-mediated phosphorylation of Cyclin E:Cdk2, Drosophila melanogaster"
Reactome:REACT_113269 "Activation of S6K1, Saccharomyces cerevisiae"
Reactome:REACT_113435 "Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta, Oryza sativa"
Reactome:REACT_113527 "Autophosphorylation of DNA-PKcs, Bos taurus"
Reactome:REACT_113569 "Activation of Cdc25C, Saccharomyces cerevisiae"
Reactome:REACT_113811 "Phosphorylation of Ribosomal protein S6 by activated S6K1, Bos taurus"
Reactome:REACT_113820 "Phosphorylation of Cyclin B1 in the CRS domain, Saccharomyces cerevisiae"
Reactome:REACT_113894 "PIP2 conversion to PIP3, Caenorhabditis elegans"
Reactome:REACT_113929 "Phosphorylation of Cdc25A at Ser-123 by Chk1, Caenorhabditis elegans"
Reactome:REACT_113990 "Activation of Cdc25C, Schizosaccharomyces pombe"
Reactome:REACT_114160 "CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes, Saccharomyces cerevisiae"
Reactome:REACT_114198 "Phosphorylation of the Scc1:Cohesion Complex, Schizosaccharomyces pombe"
Reactome:REACT_114207 "Phosphorylation of Cdc25A at Ser-123 by Chk1, Schizosaccharomyces pombe"
Reactome:REACT_114227 "Phosphorylation of Cyclin E1:Cdk2 complexes by Myt1, Schizosaccharomyces pombe"
Reactome:REACT_114233 "Autophosphorylation of DNA-PKcs, Sus scrofa"
Reactome:REACT_114255 "Autophosphorylation of DNA-PKcs, Mus musculus"
Reactome:REACT_114268 "Phosphorylation of Cdc25A at Ser-123 in response to DNA damage, Schizosaccharomyces pombe"
Reactome:REACT_114280 "Phosphorylation of Cdc25A at Ser-123 in response to DNA damage, Saccharomyces cerevisiae"
Reactome:REACT_114319 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Caenorhabditis elegans"
Reactome:REACT_114323 "Activation of Cdc25C, Caenorhabditis elegans"
Reactome:REACT_114395 "Phosphorylation of DLC1 by MAPK 8, Xenopus tropicalis"
Reactome:REACT_114434 "Autophosphorylation of DNA-PKcs, Taeniopygia guttata"
Reactome:REACT_114461 "Phosphorylation of AKT2 by PDK1, Schizosaccharomyces pombe"
Reactome:REACT_114522 "Phosphorylation of BRCA1 at multiple sites by ATM, Arabidopsis thaliana"
Reactome:REACT_114553 "Phosphorylation of Cdc25A at Ser-123 by Chk1, Saccharomyces cerevisiae"
Reactome:REACT_114599 "Phosphorylation of TSC2 by PKB, Schizosaccharomyces pombe"
Reactome:REACT_114624 "Phosphorylation of Cyclin E1:Cdk2 complexes by Myt1, Drosophila melanogaster"
Reactome:REACT_114771 "Phosphorylation of Ribosomal protein S6 by activated S6K1, Canis familiaris"
Reactome:REACT_114906 "Phosphorylation and activation of eIF4G by activated S6K1, Arabidopsis thaliana"
Reactome:REACT_114984 "Autophosphorylation of DNA-PKcs, Xenopus tropicalis"
Reactome:REACT_115006 "Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta, Caenorhabditis elegans"
Reactome:REACT_115135 "Phosphorylation and activation of eIF4G by activated S6K1, Dictyostelium discoideum"
Reactome:REACT_115168 "Autophosphorylation of DNA-PKcs, Gallus gallus"
Reactome:REACT_115199 "Autophosphorylation of DNA-PKcs, Canis familiaris"
Reactome:REACT_115358 "Phosphorylation of Cyclin E:Cdk2 complexes by Wee-1, Drosophila melanogaster"
Reactome:REACT_115384 "CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes, Schizosaccharomyces pombe"
Reactome:REACT_115440 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Danio rerio"
Reactome:REACT_115472 "Phosphorylation of the SA2 Cohesion Complex, Schizosaccharomyces pombe"
Reactome:REACT_115475 "CAK-mediated phosphorylation of Cyclin E:Cdk2, Schizosaccharomyces pombe"
Reactome:REACT_115521 "Autophosphorylation of DNA-PKcs, Danio rerio"
Reactome:REACT_115527 "Phosphorylation of Cdc25A at Ser-123 by Chk2, Schizosaccharomyces pombe"
Reactome:REACT_29759 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex, Bos taurus"
Reactome:REACT_32906 "Phosphorylation and inactivation of eEF2K by activated S6K1, Sus scrofa"
Reactome:REACT_79125 "SOS phosphorylation and dissociation (IRS), Bos taurus"
Reactome:REACT_80632 "Phosphorylation of L1 by ERK, Schizosaccharomyces pombe"
Reactome:REACT_83089 "Inactivation of Myt1 kinase, Saccharomyces cerevisiae"
Reactome:REACT_83110 "Phosphorylation (Ser5) of RNA pol II CTD, Schizosaccharomyces pombe"
Reactome:REACT_85449 "Phosphorylation and activation of eIF4G by activated S6K1, Bos taurus"
Reactome:REACT_86211 "Activation of the Anaphase Promoting Complex (APC) by Plk1, Saccharomyces cerevisiae"
Reactome:REACT_86533 "Cdc6 protein is phosphorylated by CDK, Sus scrofa"
Reactome:REACT_94248 "SOS phosphorylation and dissociation (SHC), Bos taurus"
Reactome:REACT_96088 "Phosphorylation of PDE3B, Sus scrofa"
Reactome:REACT_96877 "Phosphorylation of MDM2 at serine-395 by ATM kinase, Sus scrofa"
Reactome:REACT_97458 "Activation of the Anaphase Promoting Complex (APC) by Plk1, Dictyostelium discoideum"
GO:0016307 : phosphatidylinositol phosphate kinase activity
def
Catalysis of the phosphorylation of phosphatidylinositol phosphate to produce phosphatidylinositol bisphosphate.
is_a
GO:0004428
def
Catalysis of the reaction: ATP + a phosphatidylinositol phosphate = ADP + a phosphatidylinositol bisphosphate.
is_a
GO:0016301
GO:0016314 : phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
xref
Reactome:REACT_109476 "Hydrolysis of PIP3 to PIP2, Sus scrofa"
Reactome:REACT_77049 "PTEN dephosphorylates PIP3, Caenorhabditis elegans"
Reactome:REACT_77912 "Hydrolysis of PIP3 to PI(3,4)P2, Sus scrofa"
xref
Reactome:REACT_103500 "PTEN dephosphorylates PIP3, Caenorhabditis elegans"
Reactome:REACT_109496 "Hydrolysis of PIP3 to PI(3,4)P2, Sus scrofa"
Reactome:REACT_114681 "Hydrolysis of PIP3 to PIP2, Dictyostelium discoideum"
Reactome:REACT_115120 "PTEN dephosphorylates PIP3, Dictyostelium discoideum"
Reactome:REACT_82001 "Hydrolysis of PIP3 to PIP2, Sus scrofa"
GO:0016362 : activin receptor activity, type II
xref
Reactome:REACT_87581 "Type II receptor phosphorylates type I receptor, Sus scrofa"
xref
Reactome:REACT_91116 "Type II receptor phosphorylates type I receptor, Sus scrofa"
GO:0016402 : pristanoyl-CoA oxidase activity
xref
Reactome:REACT_104641 "(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX2), Dictyostelium discoideum"
Reactome:REACT_31617 "(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX2), Caenorhabditis elegans"
Reactome:REACT_99484 "(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX2), Drosophila melanogaster"
xref
Reactome:REACT_113674 "(2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3), Xenopus tropicalis"
GO:0016405 : CoA-ligase activity
xref
Reactome:REACT_102995 "benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate, Gallus gallus"
Reactome:REACT_106980 "phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate, Taeniopygia guttata"
Reactome:REACT_107257 "phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate, Gallus gallus"
Reactome:REACT_33784 "phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate, Danio rerio"
Reactome:REACT_33833 "benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate, Taeniopygia guttata"
Reactome:REACT_34379 "benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate, Danio rerio"
Reactome:REACT_34468 "salicylic acid + Coenzyme A + ATP => salicylate-CoA + AMP + pyrophosphate, Taeniopygia guttata"
Reactome:REACT_83697 "salicylic acid + Coenzyme A + ATP => salicylate-CoA + AMP + pyrophosphate, Sus scrofa"
Reactome:REACT_90522 "salicylic acid + Coenzyme A + ATP => salicylate-CoA + AMP + pyrophosphate, Gallus gallus"
Reactome:REACT_93894 "salicylic acid + Coenzyme A + ATP => salicylate-CoA + AMP + pyrophosphate, Danio rerio"
Reactome:REACT_98425 "benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate, Sus scrofa"
xref
Reactome:REACT_107383 "salicylic acid + Coenzyme A + ATP => salicylate-CoA + AMP + pyrophosphate, Sus scrofa"
Reactome:REACT_112091 "benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate, Dictyostelium discoideum"
Reactome:REACT_112778 "salicylic acid + Coenzyme A + ATP => salicylate-CoA + AMP + pyrophosphate, Dictyostelium discoideum"
Reactome:REACT_113679 "phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate, Dictyostelium discoideum"
Reactome:REACT_91132 "benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate, Sus scrofa"
GO:0016407 : acetyltransferase activity
xref
Reactome:REACT_115357 "Acetylation of SL1, Xenopus tropicalis"
GO:0016463 : zinc-exporting ATPase activity
synonym
"zn2+-exporting ATPase activity" EXACT [EC:3.6.3.5]
GO:0016491 : oxidoreductase activity
xref
Reactome:REACT_115316 "palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR1], Drosophila melanogaster"
GO:0016493 : C-C chemokine receptor activity
is_a
GO:0019957
relationship
has_part GO:0019957
GO:0016494 : C-X-C chemokine receptor activity
is_a
GO:0019958
relationship
has_part GO:0019958
GO:0016495 : C-X3-C chemokine receptor activity
is_a
GO:0019960
relationship
has_part GO:0019960
GO:0016502 : nucleotide receptor activity
relationship
has_part GO:0000166
GO:0016508 : long-chain-enoyl-CoA hydratase activity
xref
Reactome:REACT_29741 "trans-2,3-dehydrohexacosanoyl-CoA + H2O => 3-hydroxyhexacosanoyl-CoA, Dictyostelium discoideum"
Reactome:REACT_99663 "trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA, Mycobacterium tuberculosis"
xref
Reactome:REACT_107128 "trans-2,3-dehydrohexacosanoyl-CoA + H2O => 3-hydroxyhexacosanoyl-CoA, Dictyostelium discoideum"
GO:0016515 : interleukin-13 receptor activity
is_a
GO:0019973
relationship
has_part GO:0019973
GO:0016517 : interleukin-12 receptor activity
is_a
GO:0019972
relationship
has_part GO:0019972
GO:0016518 : interleukin-14 receptor activity
is_a
GO:0019974
relationship
has_part GO:0019974
GO:0016556 : mRNA modification
xref
Reactome:REACT_29993 "mRNA Editing, Sus scrofa"
xref
Reactome:REACT_113194 "mRNA Editing, Caenorhabditis elegans"
Reactome:REACT_114458 "mRNA Editing, Schizosaccharomyces pombe"
Reactome:REACT_114695 "mRNA Editing, Saccharomyces cerevisiae"
Reactome:REACT_29117 "mRNA Editing, Sus scrofa"
GO:0016651 : oxidoreductase activity, acting on NADH or NADPH
xref
Reactome:REACT_110665 "Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA, Mycobacterium tuberculosis"
GO:0016746 : transferase activity, transferring acyl groups
xref
Reactome:REACT_28750 "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine, Sus scrofa"
xref
Reactome:REACT_113663 "Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate, Gallus gallus"
Reactome:REACT_115059 "Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate, Gallus gallus"
Reactome:REACT_115499 "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine, Gallus gallus"
Reactome:REACT_99705 "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine, Sus scrofa"
GO:0016768 : spermine synthase activity
xref
Reactome:REACT_104354 "dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine, Rattus norvegicus"
xref
Reactome:REACT_112099 "dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine, Oryza sativa"
Reactome:REACT_113566 "dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine, Mycobacterium tuberculosis"
Reactome:REACT_114841 "dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine, Arabidopsis thaliana"
GO:0016780 : phosphotransferase activity, for other substituted phosphate groups
xref
Reactome:REACT_100281 "mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (acyl-GPI) + diacylglycerol, Sus scrofa"
Reactome:REACT_33481 "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol, Sus scrofa"
Reactome:REACT_79100 "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol, Dictyostelium discoideum"
Reactome:REACT_85831 "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol, Saccharomyces cerevisiae"
xref
Reactome:REACT_104119 "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol, Dictyostelium discoideum"
Reactome:REACT_111955 "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol, Xenopus tropicalis"
Reactome:REACT_113237 "(ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI, Saccharomyces cerevisiae"
Reactome:REACT_113436 "mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (acyl-GPI) + diacylglycerol, Saccharomyces cerevisiae"
Reactome:REACT_114047 "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol, Drosophila melanogaster"
Reactome:REACT_32683 "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol, Sus scrofa"
Reactome:REACT_83736 "mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol, Saccharomyces cerevisiae"
Reactome:REACT_84128 "mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (acyl-GPI) + diacylglycerol, Sus scrofa"
GO:0016787 : hydrolase activity
xref
Reactome:REACT_111159 "Partial proteolysis of antigen in phagolysosomes, Homo sapiens"
GO:0016788 : hydrolase activity, acting on ester bonds
xref
Reactome:REACT_30929 "uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid, Sus scrofa"
xref
Reactome:REACT_112177 "uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid, Xenopus tropicalis"
Reactome:REACT_88314 "uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid, Sus scrofa"
GO:0016831 : carboxy-lyase activity
xref
Reactome:REACT_30017 "2-amino-3-carboxymuconate semialdehyde => 2-aminomuconate semialdehyde + CO2, Bos taurus"
xref
Reactome:REACT_30831 "2-amino-3-carboxymuconate semialdehyde => 2-aminomuconate semialdehyde + CO2, Bos taurus"
GO:0016860 : intramolecular oxidoreductase activity
xref
Reactome:REACT_88198 "Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA, Bos taurus"
xref
Reactome:REACT_34789 "Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA, Bos taurus"
GO:0016887 : ATPase activity
xref
Reactome:REACT_113271 "Trafficking of GluR2-containing AMPA receptors to synapse, Xenopus tropicalis"
GO:0016896 : exoribonuclease activity, producing 5'-phosphomonoesters
xref
Reactome:REACT_101255 "Decapping of mRNA by the DCP1-DCP2 Complex, Rattus norvegicus"
GO:0016985 : mannan endo-1,4-beta-mannosidase activity
def
Catalysis of the random hydrolysis of 1,4-beta-D-mannosidic linkages in mannans, galactomannans, glucomannans, and galactoglucomannans.
def
Catalysis of the random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans, glucomannans, and galactoglucomannans.
GO:0017018 : myosin phosphatase activity
xref
Reactome:REACT_99052 "ATP Hydrolysis By Myosin, Drosophila melanogaster"
GO:0017040 : ceramidase activity
xref
Reactome:REACT_112340 "ceramide + H2O <=> stearate + sphingosine [endoplasmic reticulum], Arabidopsis thaliana"
Reactome:REACT_112467 "ceramide + H2O <=> stearate + sphingosine [endoplasmic reticulum], Oryza sativa"
Reactome:REACT_113330 "ceramide + H2O => stearate + sphingosine [Golgi], Dictyostelium discoideum"
Reactome:REACT_113430 "ceramide + H2O => stearate + sphingosine [Golgi], Oryza sativa"
Reactome:REACT_114429 "ceramide + H2O <=> stearate + sphingosine [endoplasmic reticulum], Dictyostelium discoideum"
Reactome:REACT_115217 "ceramide + H2O <=> stearate + sphingosine [endoplasmic reticulum], Drosophila melanogaster"
Reactome:REACT_115458 "ceramide + H2O => stearate + sphingosine [Golgi], Arabidopsis thaliana"
GO:0017050 : D-erythro-sphingosine kinase activity
xref
Reactome:REACT_114199 "sphingosine +ATP => sphingosine 1-phosphate + ADP, Caenorhabditis elegans"
GO:0017057 : 6-phosphogluconolactonase activity
xref
Reactome:REACT_94359 "D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate, Sus scrofa"
xref
Reactome:REACT_110192 "D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate, Sus scrofa"
GO:0017060 : 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity
synonym
"(Le(a))-dependent (alpha-3/4)-fucosyltransferase activity" NARROW [EC:2.4.1.65]
"(Lea)-dependent (alpha-3/4)-fucosyltransferase activity" EXACT [EC:2.4.1.65]
"alpha(1,3/1,4) fucosyltransferase III" RELATED [EC:2.4.1.65]
"alpha(1,4)-L-fucosyltransferase activity" EXACT []
"alpha-(1,3/1,4) fucosyltransferase III activity" EXACT [EC:2.4.1.65]
"alpha-(1->4)-L-fucosyltransferase activity" EXACT [EC:2.4.1.65]
"alpha-4-L-fucosyltransferase activity" EXACT [EC:2.4.1.65]
"beta-acetylglucosaminylsaccharide fucosyltransferase activity" EXACT [EC:2.4.1.65]
"blood group Lewis alpha-4-fucosyltransferase activity" NARROW [EC:2.4.1.65]
"blood group Lewis alpha-4-fucosyltransferase" NARROW [EC:2.4.1.65]
"blood-group substance Le(a)-dependent fucosyltransferase activity" NARROW [EC:2.4.1.65]
"blood-group substance Lea-dependent fucosyltransferase" NARROW [EC:2.4.1.65]
"FucT-II activity" EXACT [EC:2.4.1.65]
"galactoside 3(4)-L-fucosyltransferase activity" EXACT []
"Lewis alpha-(1->3/4)-fucosyltransferase activity" NARROW [EC:2.4.1.65]
"Lewis alpha-(1->3/4)-fucosyltransferase" NARROW [EC:2.4.1.65]
"Lewis blood group alpha-(1->3/4)-fucosyltransferase activity" NARROW [EC:2.4.1.65]
"Lewis blood group alpha-(1->3/4)-fucosyltransferase" NARROW [EC:2.4.1.65]
"Lewis FT activity" NARROW [EC:2.4.1.65]
"Lewis(Le) blood group gene-dependent alpha-(1->3/4)-L-fucosyltransferase" NARROW [EC:2.4.1.65]
synonym
"(Le(a))-dependent (alpha-3/4)-fucosyltransferase activity" BROAD [EC:2.4.1.65]
"(Lea)-dependent (alpha-3/4)-fucosyltransferase activity" BROAD [EC:2.4.1.65]
"alpha(1,4)-L-fucosyltransferase activity" BROAD []
"alpha-(1,3/1,4) fucosyltransferase III activity" BROAD [EC:2.4.1.65]
"alpha-(1,4)-L-fucosyltransferase activity" BROAD [EC:2.4.1.65]
"alpha-(1->4)-L-fucosyltransferase activity" BROAD [EC:2.4.1.65]
"alpha-4-L-fucosyltransferase activity" BROAD [EC:2.4.1.65]
"beta-acetylglucosaminylsaccharide fucosyltransferase activity" BROAD [EC:2.4.1.65]
"blood group Lewis alpha-4-fucosyltransferase activity" BROAD [EC:2.4.1.65]
"blood-group substance Le(a)-dependent fucosyltransferase activity" BROAD [EC:2.4.1.65]
"blood-group substance Lea-dependent fucosyltransferase" BROAD [EC:2.4.1.65]
"FucT-II activity" BROAD [EC:2.4.1.65]
"galactoside 3(4)-L-fucosyltransferase activity" BROAD []
"Lewis alpha-(1,3/4)-fucosyltransferase activity" BROAD [EC:2.4.1.65]
"Lewis alpha-(1->3/4)-fucosyltransferase activity" BROAD [EC:2.4.1.65]
"Lewis blood group alpha-(1,3/4)-fucosyltransferase activity" BROAD [EC:2.4.1.65]
"Lewis blood group alpha-(1->3/4)-fucosyltransferase activity" BROAD [EC:2.4.1.65]
"Lewis FT activity" BROAD [EC:2.4.1.65]
"Lewis(Le) blood group gene-dependent alpha-(1,3/4)-L-fucosyltransferase activity" BROAD []
GO:0017081 : chloride channel regulator activity
xref
Reactome:REACT_96291 "HCO3- transport through ion channel, Caenorhabditis elegans"
xref
Reactome:REACT_112601 "HCO3- transport through ion channel, Escherichia coli"
GO:0017120 : polyphosphatidylinositol phosphatase activity
def
Catalysis of the conversion of phosphatidylinositol-3-phosphate, phosphatidylinositol-4-phosphate, and phosphatidylinositol-3,5-bisphosphate, but not PI-4,5-bisphosphate, to phosphatidylinositol; PPIPase activity is a key regulator of membrane trafficking and actin cytoskeleton organization.
is_a
GO:0016791
def
OBSOLETE. Catalysis of the conversion of phosphatidylinositol-3-phosphate, phosphatidylinositol-4-phosphate, and phosphatidylinositol-3,5-bisphosphate, but not PI-4,5-bisphosphate, to phosphatidylinositol; PPIPase activity is a key regulator of membrane trafficking and actin cytoskeleton organization.
comment
This term was made obsolete because it represents a gene product.
is_obsolete
true
consider
GO:0004438
GO:0034593
GO:0043812
GO:0017127 : cholesterol transporter activity
xref
Reactome:REACT_109869 "NPC1L1-mediated phytosterol uptake, Drosophila melanogaster"
Reactome:REACT_71556 "NPC1L1-mediated cholesterol uptake, Sus scrofa"
Reactome:REACT_79442 "NPC1L1-mediated cholesterol uptake, Caenorhabditis elegans"
Reactome:REACT_88915 "NPC1L1-mediated cholesterol uptake, Drosophila melanogaster"
xref
Reactome:REACT_111034 "ABCG4 may mediate cholesterol efflux, Homo sapiens"
Reactome:REACT_112797 "NPC1L1-mediated cholesterol uptake, Plasmodium falciparum"
Reactome:REACT_112970 "NPC1L1-mediated phytosterol uptake, Plasmodium falciparum"
Reactome:REACT_113155 "ABCG1-mediated transport of intracellular cholesterol to the cell surface, Taeniopygia guttata"
Reactome:REACT_113203 "ABCG1-mediated transport of intracellular cholesterol to the cell surface, Xenopus tropicalis"
Reactome:REACT_31143 "NPC1L1-mediated cholesterol uptake, Sus scrofa"
Reactome:REACT_84159 "NPC1L1-mediated cholesterol uptake, Caenorhabditis elegans"
GO:0017144 : drug metabolic process
xref
Reactome:REACT_80439 "Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI), Xenopus tropicalis"
GO:0017187 : peptidyl-glutamic acid carboxylation
xref
Reactome:REACT_113315 "Gamma-carboxylation, transport, and amino-terminal cleavage of proteins, Drosophila melanogaster"
GO:0018279 : protein N-linked glycosylation via asparagine
xref
Reactome:REACT_30384 "Synthesis of dolichyl-phosphate-glucose, Schizosaccharomyces pombe"
xref
Reactome:REACT_31319 "Synthesis of dolichyl-phosphate-glucose, Schizosaccharomyces pombe"
GO:0018467 : formaldehyde dehydrogenase activity
is_a
GO:0016620
is_a
GO:0004029
GO:0018474 : 2-carboxybenzaldehyde dehydrogenase activity
is_a
GO:0016620
is_a
GO:0004029
GO:0018477 : benzaldehyde dehydrogenase (NADP+) activity
is_a
GO:0016620
is_a
GO:0033721
GO:0018479 : benzaldehyde dehydrogenase (NAD+) activity
is_a
GO:0016620
is_a
GO:0004029
GO:0018484 : 4-hydroxybenzaldehyde dehydrogenase activity
is_a
GO:0016620
is_a
GO:0004029
GO:0018485 : salicylaldehyde dehydrogenase activity
is_a
GO:0016620
is_a
GO:0004029
GO:0018564 : carbazole 1,9a-dioxygenase activity
synonym
"carbazole 1,9alpha-dioxygenase activity" EXACT []
GO:0018771 : 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity
name
2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase activity
def
Catalysis of the reaction: 2-hydroxy-6-keto-nona-2,4-dienedioate + OH- = cis-2-hydroxypenta-2,4-dienoate + succinate.
xref
EC:3.7.1.-
UM-BBD_enzymeID:e0310
name
2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity
def
Catalysis of the reaction: (2E,4Z)-2-hydroxy-6-oxonona-2,4-dienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + H+ + succinate.
synonym
"(2E,4Z)-2-hydroxy-6-oxona-2,4-dienedioate succinylhydrolase activity" EXACT systematic_synonym [EC:3.7.1.14]
"2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase activity" EXACT [UM-BBD_reactionID:r0438]
xref
EC:3.7.1.14
MetaCyc:MHPCHYDROL-RXN
RHEA:24792
UM-BBD_reactionID:r0438
GO:0018885 : carbon tetrachloride metabolic process
xref
Reactome:REACT_104637 "Dehalogenation of carbon tetrachloride to form a free radical, Sus scrofa"
Reactome:REACT_31583 "Dehalogenation of carbon tetrachloride to form a free radical, Xenopus tropicalis"
xref
Reactome:REACT_32769 "Dehalogenation of carbon tetrachloride to form a free radical, Sus scrofa"
GO:0018910 : benzene metabolic process
xref
Reactome:REACT_101063 "Benzene is hydroxylated to phenol, Xenopus tropicalis"
Reactome:REACT_55692 "Benzene is hydroxylated to phenol, Sus scrofa"
xref
Reactome:REACT_31871 "Benzene is hydroxylated to phenol, Sus scrofa"
GO:0019001 : guanyl nucleotide binding
xref
Reactome:REACT_76983 "eEF1A complexes with GTP, Xenopus tropicalis"
Reactome:REACT_84177 "eEF1A complexes with GTP, Caenorhabditis elegans"
Reactome:REACT_84736 "eEF1A complexes with GTP, Sus scrofa"
Reactome:REACT_87810 "eEF1A complexes with GTP, Arabidopsis thaliana"
Reactome:REACT_90492 "eEF1A complexes with GTP, Taeniopygia guttata"
Reactome:REACT_98519 "eEF1A complexes with GTP, Oryza sativa"
Reactome:REACT_99590 "eEF1A complexes with GTP, Saccharomyces cerevisiae"
xref
Reactome:REACT_106634 "eEF1A complexes with GTP, Saccharomyces cerevisiae"
GO:0019104 : DNA N-glycosylase activity
xref
Reactome:REACT_85718 "Cleavage of ethenocytosine by TDG glycosylase, Schizosaccharomyces pombe"
xref
Reactome:REACT_104604 "Cleavage of ethenocytosine by TDG glycosylase, Schizosaccharomyces pombe"
GO:0019107 : myristoyltransferase activity
xref
Reactome:REACT_100750 "Myristoylation of tBID by NMT1, Bos taurus"
xref
Reactome:REACT_32161 "Myristoylation of tBID by NMT1, Bos taurus"
GO:0019108 : aryl-aldehyde dehydrogenase (NAD) activity
is_a
GO:0016620
is_a
GO:0004029
GO:0019115 : benzaldehyde dehydrogenase activity
is_a
GO:0016620
is_a
GO:0004030
GO:0019135 : deoxyhypusine monooxygenase activity
xref
Reactome:REACT_92455 "EIF5A(Dhp) + O2 => EIF5A(Hyp), Plasmodium falciparum"
xref
Reactome:REACT_114901 "EIF5A(Dhp) + O2 => EIF5A(Hyp), Caenorhabditis elegans"
GO:0019140 : inositol 3-kinase activity
is_a
GO:0004428
is_a
GO:0016301
GO:0019145 : aminobutyraldehyde dehydrogenase activity
is_a
GO:0016620
is_a
GO:0004029
GO:0019187 : beta-1,4-mannosyltransferase activity
def
Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming a beta-1,4-linkage.
def
Catalysis of the transfer of a mannose residue to an oligosaccharide, forming a beta-(1->4) linkage.
GO:0019206 : nucleoside kinase activity
xref
Reactome:REACT_81871 "cytidine or uridine + ATP => CMP or UMP + ADP [UCK2], Sus scrofa"
Reactome:REACT_82505 "cytidine or uridine + ATP => CMP or UMP + ADP [UCK2], Danio rerio"
Reactome:REACT_91512 "cytidine or uridine + ATP => CMP or UMP + ADP [UCK1], Drosophila melanogaster"
xref
Reactome:REACT_100134 "cytidine or uridine + ATP => CMP or UMP + ADP [UCK2], Sus scrofa"
Reactome:REACT_112294 "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP [AK5], Caenorhabditis elegans"
Reactome:REACT_112710 "cytidine or uridine + ATP => CMP or UMP + ADP [UCK1], Dictyostelium discoideum"
Reactome:REACT_112874 "cytidine or uridine + ATP => CMP or UMP + ADP [UCK1], Arabidopsis thaliana"
Reactome:REACT_112935 "thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1], Arabidopsis thaliana"
Reactome:REACT_113015 "(d)AMP or (d)CMP + ATP <=> (d)ADP or (d)CDP + ADP [AK5], Escherichia coli"
Reactome:REACT_113048 "cytidine or uridine + ATP => CMP or UMP + ADP [UCK1], Drosophila melanogaster"
Reactome:REACT_113383 "(d)AMP or (d)CMP + ATP <=> (d)ADP or (d)CDP + ADP [AK5], Caenorhabditis elegans"
Reactome:REACT_113689 "deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2], Arabidopsis thaliana"
Reactome:REACT_113816 "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP [AK5], Escherichia coli"
Reactome:REACT_114509 "deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2], Oryza sativa"
Reactome:REACT_114837 "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP [AK5], Xenopus tropicalis"
Reactome:REACT_114962 "(d)AMP or (d)CMP + ATP <=> (d)ADP or (d)CDP + ADP [AK5], Xenopus tropicalis"
Reactome:REACT_115045 "cytidine or uridine + ATP => CMP or UMP + ADP [UCK1], Oryza sativa"
GO:0019244 : lactate biosynthetic process from pyruvate
synonym
"pyruvate fermentation to lactate" EXACT []
GO:0019246 : L(+)-lactate biosynthetic process from pyruvate
def
The chemical reactions and pathways resulting in the formation of L(+)lactate from other compounds, including pyruvate.
def
The chemical reactions and pathways resulting in the formation of L(+)-lactate from other compounds, including pyruvate.
synonym
"S-lactate biosynthetic process from pyruvate" EXACT []
xref
MetaCyc:PWY-5481
GO:0019370 : leukotriene biosynthetic process
xref
Reactome:REACT_113490 "Leukotriene synthesis, Mycobacterium tuberculosis"
GO:0019388 : galactose catabolic process
xref
Reactome:REACT_92286 "Galactose catabolism, Sus scrofa"
xref
Reactome:REACT_33886 "Galactose catabolism, Sus scrofa"
GO:0019432 : triglyceride biosynthetic process
xref
Reactome:REACT_96275 "Triglyceride Biosynthesis, Schizosaccharomyces pombe"
xref
Reactome:REACT_81530 "Triglyceride Biosynthesis, Schizosaccharomyces pombe"
GO:0019433 : triglyceride catabolic process
xref
Reactome:REACT_112141 "Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis, Oryza sativa"
Reactome:REACT_114503 "Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis, Arabidopsis thaliana"
Reactome:REACT_115465 "Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis, Staphylococcus aureus N315"
GO:0019674 : NAD metabolic process
xref
Reactome:REACT_80887 "Nicotinate metabolism, Dictyostelium discoideum"
xref
Reactome:REACT_105395 "Nicotinate metabolism, Dictyostelium discoideum"
GO:0019763 : immunoglobulin receptor activity
is_a
GO:0019865
relationship
has_part GO:0019865
GO:0019766 : IgA receptor activity
is_a
GO:0019862
relationship
has_part GO:0019862
GO:0019767 : IgE receptor activity
is_a
GO:0019863
relationship
has_part GO:0019863
GO:0019770 : IgG receptor activity
is_a
GO:0019864
relationship
has_part GO:0019864
GO:0019825 : oxygen binding
xref
Reactome:REACT_100468 "MEOS oxidizes ethanol to acetaldehyde, Xenopus tropicalis"
Reactome:REACT_101063 "Benzene is hydroxylated to phenol, Xenopus tropicalis"
Reactome:REACT_102873 "CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation, Xenopus tropicalis"
Reactome:REACT_103342 "N-hydroxylation of 4-aminobiphenyl, Bos taurus"
Reactome:REACT_104205 "CYP2U1 can omega-hydroxylate arachidonate, Drosophila melanogaster"
Reactome:REACT_104637 "Dehalogenation of carbon tetrachloride to form a free radical, Sus scrofa"
Reactome:REACT_104903 "CYP4F12 hydroxylates arachidonic acid, Bos taurus"
Reactome:REACT_105192 "CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation, Xenopus tropicalis"
Reactome:REACT_105335 "CYP3A4 can N-demethylate loperaminde, Caenorhabditis elegans"
Reactome:REACT_106014 "CYP3A7 can 6beta-hydroxylate testosterone, Caenorhabditis elegans"
Reactome:REACT_106170 "Vinyl chloride is oxidized to 2-Chloroethylene oxide, Sus scrofa"
Reactome:REACT_107892 "S-atom dealkylation of 6-methylmercaptopurine, Sus scrofa"
Reactome:REACT_108293 "CYP3A7 can 6beta-hydroxylate testosterone, Bos taurus"
Reactome:REACT_108791 "CYP3A5 oxidises aflatoxin B1 to aflatoxin-8,9-oxide, Rattus norvegicus"
Reactome:REACT_28179 "CYP3A7 can 6beta-hydroxylate testosterone, Rattus norvegicus"
Reactome:REACT_28328 "CYP3A5 oxidises aflatoxin B1 to aflatoxin-8,9-oxide, Caenorhabditis elegans"
Reactome:REACT_30377 "CYP4F12 hydroxylates arachidonic acid, Sus scrofa"
Reactome:REACT_31583 "Dehalogenation of carbon tetrachloride to form a free radical, Xenopus tropicalis"
Reactome:REACT_54494 "CYP3A4 can N-demethylate loperaminde, Rattus norvegicus"
Reactome:REACT_55692 "Benzene is hydroxylated to phenol, Sus scrofa"
Reactome:REACT_79362 "CYP4F2 omega-hydroxylates leukotriene B4, thus inactivating it, Bos taurus"
Reactome:REACT_79520 "CYP4F2 omega-hydroxylates leukotriene B4, thus inactivating it, Canis familiaris"
Reactome:REACT_80439 "Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI), Xenopus tropicalis"
Reactome:REACT_82285 "CYP3A7 can 6beta-hydroxylate testosterone, Canis familiaris"
Reactome:REACT_83612 "CYP3A5 oxidises aflatoxin B1 to aflatoxin-8,9-oxide, Bos taurus"
Reactome:REACT_85590 "CYP4F8 hydroxylates prostaglandin H2, Bos taurus"
Reactome:REACT_87157 "CYP4F8 hydroxylates prostaglandin H2, Canis familiaris"
Reactome:REACT_87584 "CYP3A5 oxidises aflatoxin B1 to aflatoxin-8,9-oxide, Canis familiaris"
Reactome:REACT_91396 "CYP3A4 can N-demethylate loperaminde, Bos taurus"
Reactome:REACT_92591 "Vinyl chloride is oxidized to 2-Chloroethylene oxide, Xenopus tropicalis"
Reactome:REACT_92861 "CYP4F3 omega-hydroxylates leukotriene B4, thus inactivating it, Bos taurus"
Reactome:REACT_92887 "CYP4F2 omega-hydroxylates leukotriene B4, thus inactivating it, Sus scrofa"
Reactome:REACT_94199 "CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation, Xenopus tropicalis"
Reactome:REACT_97585 "Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide, Xenopus tropicalis"
Reactome:REACT_97637 "CYP2C19 5-hydroxylates omeprazole, Xenopus tropicalis"
Reactome:REACT_98611 "CYP3A4 can N-demethylate loperaminde, Canis familiaris"
Reactome:REACT_98613 "CYP2U1 can omega-hydroxylate arachidonate, Caenorhabditis elegans"
Reactome:REACT_98733 "CYP4F12 hydroxylates arachidonic acid, Canis familiaris"
xref
Reactome:REACT_102736 "S-atom dealkylation of 6-methylmercaptopurine, Sus scrofa"
Reactome:REACT_112032 "CYP3A4 can N-demethylate loperaminde, Taeniopygia guttata"
Reactome:REACT_112331 "S-atom dealkylation of 6-methylmercaptopurine, Danio rerio"
Reactome:REACT_112347 "N-atom dealkylation of caffeine, Danio rerio"
Reactome:REACT_112584 "S-atom dealkylation of 6-methylmercaptopurine, Gallus gallus"
Reactome:REACT_112653 "Ethylene is oxidized to Ethylene oxide by CYP1A1, Gallus gallus"
Reactome:REACT_112751 "CYP1B1 4-hydroxylates estradiol-17beta, Danio rerio"
Reactome:REACT_112900 "N-atom dealkylation of caffeine, Gallus gallus"
Reactome:REACT_113220 "CYP3A5 oxidises aflatoxin B1 to aflatoxin-8,9-oxide, Taeniopygia guttata"
Reactome:REACT_113292 "N-hydroxylation of 4-aminobiphenyl, Danio rerio"
Reactome:REACT_113841 "Ethylene is oxidized to Ethylene oxide by CYP1A1, Danio rerio"
Reactome:REACT_114039 "N-hydroxylation of 4-aminobiphenyl, Gallus gallus"
Reactome:REACT_114317 "CYP3A7 can 6beta-hydroxylate testosterone, Taeniopygia guttata"
Reactome:REACT_31871 "Benzene is hydroxylated to phenol, Sus scrofa"
Reactome:REACT_32769 "Dehalogenation of carbon tetrachloride to form a free radical, Sus scrofa"
Reactome:REACT_33304 "CYP4F3 omega-hydroxylates leukotriene B4, thus inactivating it, Bos taurus"
Reactome:REACT_79087 "N-hydroxylation of 4-aminobiphenyl, Bos taurus"
Reactome:REACT_93076 "Vinyl chloride is oxidized to 2-Chloroethylene oxide, Sus scrofa"
GO:0022416 : chaeta development
name
bristle development
def
The process whose specific outcome is the progression of the bristle over time, from its formation to the mature structure. A bristle is an insect sensory organ.
name
chaeta development
def
The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.
synonym
"bristle development" NARROW [GOC:bf, GOC:dos]
GO:0022803 : passive transmembrane transporter activity
xref
Reactome:REACT_105657 "Passive I- efflux mediated by SMCT1, Sus scrofa"
Reactome:REACT_108557 "Passive I- efflux mediated by SMCT1, Xenopus tropicalis"
Reactome:REACT_30399 "Passive I- efflux mediated by SMCT1, Gallus gallus"
Reactome:REACT_31260 "Passive I- efflux mediated by SMCT1, Taeniopygia guttata"
Reactome:REACT_84103 "Passive I- efflux mediated by SMCT1, Danio rerio"
Reactome:REACT_86462 "Passive I- efflux mediated by SMCT1, Mus musculus"
Reactome:REACT_90623 "Passive I- efflux mediated by SMCT1, Bos taurus"
Reactome:REACT_91343 "Passive I- efflux mediated by SMCT1, Rattus norvegicus"
Reactome:REACT_95668 "Passive I- efflux mediated by SMCT1, Canis familiaris"
Reactome:REACT_96728 "Passive I- efflux mediated by SMCT1, Staphylococcus aureus N315"
GO:0022857 : transmembrane transporter activity
xref
Reactome:REACT_80497 "GLUT9 transports glucose, fructose and urate, Drosophila melanogaster"
xref
Reactome:REACT_111088 "Egress of internalized antigen to the cytosol via sec61, Homo sapiens"
Reactome:REACT_111933 "GLUT9 transports glucose, fructose and urate, Plasmodium falciparum"
Reactome:REACT_113047 "GLUT9 transports glucose, fructose and urate, Dictyostelium discoideum"
Reactome:REACT_113116 "GLUT9 transports glucose, fructose and urate, Mycobacterium tuberculosis"
Reactome:REACT_113829 "GLUT9 transports glucose, fructose and urate, Arabidopsis thaliana"
Reactome:REACT_114161 "GLUT9 transports glucose, fructose and urate, Oryza sativa"
GO:0030060 : L-malate dehydrogenase activity
xref
Reactome:REACT_100902 "Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+, Saccharomyces cerevisiae"
Reactome:REACT_29753 "(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+, Oryza sativa"
Reactome:REACT_91255 "(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+, Saccharomyces cerevisiae"
Reactome:REACT_92950 "Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+, Arabidopsis thaliana"
Reactome:REACT_97671 "(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+, Arabidopsis thaliana"
Reactome:REACT_97973 "Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+, Oryza sativa"
GO:0030168 : platelet activation
xref
Reactome:REACT_100921 "Platelet Activation, Escherichia coli"
Reactome:REACT_103583 "Platelet Activation, Mus musculus"
Reactome:REACT_105599 "Platelet Activation, Danio rerio"
Reactome:REACT_108920 "Platelet Activation, Saccharomyces cerevisiae"
Reactome:REACT_109042 "Platelet Activation, Arabidopsis thaliana"
Reactome:REACT_28166 "Platelet Activation, Rattus norvegicus"
Reactome:REACT_29092 "Platelet Activation, Caenorhabditis elegans"
Reactome:REACT_29357 "Platelet Activation, Staphylococcus aureus N315"
Reactome:REACT_32211 "Platelet Activation, Bos taurus"
Reactome:REACT_798 "Platelet Activation, Homo sapiens"
Reactome:REACT_82375 "Platelet Activation, Sus scrofa"
Reactome:REACT_82964 "Platelet Activation, Mycobacterium tuberculosis"
Reactome:REACT_83720 "Platelet Activation, Dictyostelium discoideum"
Reactome:REACT_85922 "Platelet Activation, Canis familiaris"
Reactome:REACT_86767 "Platelet Activation, Taeniopygia guttata"
Reactome:REACT_86968 "Platelet Activation, Xenopus tropicalis"
Reactome:REACT_88667 "Platelet Activation, Drosophila melanogaster"
Reactome:REACT_88938 "Platelet Activation, Gallus gallus"
Reactome:REACT_92635 "Platelet Activation, Oryza sativa"
Reactome:REACT_96250 "Platelet Activation, Schizosaccharomyces pombe"
Reactome:REACT_97013 "Platelet Activation, Plasmodium falciparum"
xref
Reactome:REACT_103583 "Platelet activation, signaling and aggregation, Mus musculus"
Reactome:REACT_105599 "Platelet activation, signaling and aggregation, Danio rerio"
Reactome:REACT_108920 "Platelet activation, signaling and aggregation, Saccharomyces cerevisiae"
Reactome:REACT_109042 "Platelet activation, signaling and aggregation, Arabidopsis thaliana"
Reactome:REACT_28166 "Platelet activation, signaling and aggregation, Rattus norvegicus"
Reactome:REACT_29092 "Platelet activation, signaling and aggregation, Caenorhabditis elegans"
Reactome:REACT_29357 "Platelet activation, signaling and aggregation, Staphylococcus aureus N315"
Reactome:REACT_32211 "Platelet activation, signaling and aggregation, Bos taurus"
Reactome:REACT_798 "Platelet activation, signaling and aggregation, Homo sapiens"
Reactome:REACT_82375 "Platelet activation, signaling and aggregation, Sus scrofa"
Reactome:REACT_82964 "Platelet activation, signaling and aggregation, Mycobacterium tuberculosis"
Reactome:REACT_83720 "Platelet activation, signaling and aggregation, Dictyostelium discoideum"
Reactome:REACT_85922 "Platelet activation, signaling and aggregation, Canis familiaris"
Reactome:REACT_86767 "Platelet activation, signaling and aggregation, Taeniopygia guttata"
Reactome:REACT_86968 "Platelet activation, signaling and aggregation, Xenopus tropicalis"
Reactome:REACT_88667 "Platelet activation, signaling and aggregation, Drosophila melanogaster"
Reactome:REACT_88938 "Platelet activation, signaling and aggregation, Gallus gallus"
Reactome:REACT_92635 "Platelet activation, signaling and aggregation, Oryza sativa"
Reactome:REACT_96250 "Platelet activation, signaling and aggregation, Schizosaccharomyces pombe"
Reactome:REACT_97013 "Platelet activation, signaling and aggregation, Plasmodium falciparum"
GO:0030200 : heparan sulfate proteoglycan catabolic process
def
The chemical reactions and pathways resulting in the breakdown of proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha1->4 linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups.
def
The chemical reactions and pathways resulting in the breakdown of proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4) linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups.
GO:0030201 : heparan sulfate proteoglycan metabolic process
def
The chemical reactions and pathways involving any proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha1->4 linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups.
def
The chemical reactions and pathways involving any proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups.
GO:0030202 : heparin metabolic process
def
The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha1->4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
def
The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
GO:0030210 : heparin biosynthetic process
def
The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha1->4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
def
The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
GO:0030211 : heparin catabolic process
def
The chemical reactions and pathways resulting in the breakdown of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha1->4-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
def
The chemical reactions and pathways resulting in the breakdown of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
GO:0030226 : apolipoprotein receptor activity
is_a
GO:0034185
relationship
has_part GO:0034185
GO:0030228 : lipoprotein particle receptor activity
is_a
GO:0071813
relationship
has_part GO:0071813
GO:0030229 : very-low-density lipoprotein particle receptor activity
is_a
GO:0034189
relationship
has_part GO:0034189
GO:0030267 : glyoxylate reductase (NADP) activity
xref
Reactome:REACT_103015 "glyoxylate + NADPH + H+ => glycolate + NADP+, Saccharomyces cerevisiae"
Reactome:REACT_104358 "glyoxylate + NADPH + H+ => glycolate + NADP+, Sus scrofa"
xref
Reactome:REACT_29565 "glyoxylate + NADPH + H+ => glycolate + NADP+, Sus scrofa"
GO:0030342 : 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity
xref
Reactome:REACT_103292 "CYP24A1 catalyzes the initial step in the deactivation of the hormonally active form of vitamin D3, Caenorhabditis elegans"
Reactome:REACT_108673 "1,25-dihydroxyvitamin D3 is deactivated, Caenorhabditis elegans"
GO:0030368 : interleukin-17 receptor activity
is_a
GO:0019975
relationship
has_part GO:0019975
GO:0030412 : formimidoyltetrahydrofolate cyclodeaminase activity
xref
Reactome:REACT_94892 "N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate, Bos taurus"
xref
Reactome:REACT_103744 "N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate, Bos taurus"
GO:0030429 : kynureninase activity
synonym
"l-kynurenine hydrolase activity" EXACT [EC:3.7.1.3]
xref
Reactome:REACT_114922 "3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine, Xenopus tropicalis"
GO:0030491 : heteroduplex formation
xref
Reactome:REACT_817 "Heteroduplex formation, Homo sapiens"
Reactome:REACT_881 "Synaptic stable pairing/D-loop structure formation between recombining DNA molecules, Homo sapiens"
GO:0030509 : BMP signaling pathway
xref
Reactome:REACT_107985 "Signaling by BMP, Caenorhabditis elegans"
GO:0030512 : negative regulation of transforming growth factor beta receptor signaling pathway
xref
Reactome:REACT_105250 "I-SMAD competes with R-SMAD for type I receptor, Danio rerio"
Reactome:REACT_6909 "I-SMAD competes with R-SMAD for type I receptor, Homo sapiens"
Reactome:REACT_81179 "I-SMAD competes with R-SMAD for type I receptor, Mus musculus"
Reactome:REACT_82804 "I-SMAD competes with R-SMAD for type I receptor, Canis familiaris"
Reactome:REACT_90968 "I-SMAD competes with R-SMAD for type I receptor, Rattus norvegicus"
Reactome:REACT_93061 "I-SMAD competes with R-SMAD for type I receptor, Xenopus tropicalis"
Reactome:REACT_93800 "I-SMAD competes with R-SMAD for type I receptor, Bos taurus"
Reactome:REACT_95269 "I-SMAD competes with R-SMAD for type I receptor, Sus scrofa"
xref
Reactome:REACT_105250 "I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1), Danio rerio"
Reactome:REACT_113798 "SKI complexes with the SMAD complex, suppressing TGF-beta signaling, Danio rerio"
Reactome:REACT_6909 "I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1), Homo sapiens"
Reactome:REACT_81179 "I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1), Mus musculus"
Reactome:REACT_82804 "I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1), Canis familiaris"
Reactome:REACT_90968 "I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1), Rattus norvegicus"
Reactome:REACT_93061 "I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1), Xenopus tropicalis"
Reactome:REACT_93800 "I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1), Bos taurus"
Reactome:REACT_95269 "I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1), Sus scrofa"
GO:0030594 : neurotransmitter receptor activity
is_a
GO:0042165
relationship
has_part GO:0042165
GO:0030676 : Rac guanyl-nucleotide exchange factor activity
xref
Reactome:REACT_112997 "Activation of Rac1 by FARP2, Xenopus tropicalis"
GO:0030776 : (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity
synonym
"(rs)-tetrahydrobenzylisoquinoline N-methyltransferase activity" EXACT [EC:2.1.1.115]
GO:0030785 : [ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity
synonym
"rubisco methyltransferase activity" EXACT [EC:2.1.1.127]
GO:0031018 : endocrine pancreas development
xref
Reactome:REACT_84766 "Regulation of beta-cell development, Plasmodium falciparum"
Reactome:REACT_97063 "Regulation of gene expression in beta cells, Dictyostelium discoideum"
xref
Reactome:REACT_112937 "Regulation of gene expression in beta cells, Mycobacterium tuberculosis"
Reactome:REACT_114067 "Regulation of beta-cell development, Mycobacterium tuberculosis"
Reactome:REACT_79285 "Regulation of gene expression in beta cells, Dictyostelium discoideum"
Reactome:REACT_80121 "Regulation of beta-cell development, Plasmodium falciparum"
GO:0031041 : O-glycan processing, core 5
def
The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 5 O-glycan structure, GalNAc-alpha-1->3-GalNAc.
def
The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 5 O-glycan structure, GalNAc-alpha-(1->3)-GalNAc.
GO:0031042 : O-glycan processing, core 6
def
The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 6 O-glycan structure, GlcNAc-beta-1->6-GalNAc.
def
The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 6 O-glycan structure, GlcNAc-beta-(1->6)-GalNAc.
GO:0031043 : O-glycan processing, core 7
def
The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 7 O-glycan structure, GalNAc-alpha-1->6-GalNAc.
def
The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 7 O-glycan structure, GalNAc-alpha-(1->6)-GalNAc.
GO:0031044 : O-glycan processing, core 8
def
The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 8 O-glycan structure, Gal-alpha-1->3-GalNAc.
def
The stepwise addition of sugar residues to the initially added O-linked sugar (usually GalNAc) to form the core 8 O-glycan structure, Gal-alpha-(1->3)-GalNAc.
GO:0031071 : cysteine desulfurase activity
synonym
"NifS" RELATED [EC:2.8.1.7]
GO:0031124 : mRNA 3'-end processing
xref
Reactome:REACT_33629 "mRNA 3'-end processing, Rattus norvegicus"
xref
Reactome:REACT_112683 "mRNA 3'-end processing, Drosophila melanogaster"
Reactome:REACT_113053 "mRNA 3'-end processing, Caenorhabditis elegans"
Reactome:REACT_114937 "mRNA 3'-end processing, Arabidopsis thaliana"
Reactome:REACT_115007 "mRNA 3'-end processing, Oryza sativa"
GO:0031127 : alpha-(1,2)-fucosyltransferase activity
name
alpha(1,2)-fucosyltransferase activity
def
Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha(1,2)-linkage.
name
alpha-(1,2)-fucosyltransferase activity
def
Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->2) linkage.
synonym
"alpha-(1->2)-fucosyltransferase activity" EXACT []
"alpha-1,2-fucosyltransferase activity" EXACT []
GO:0031145 : anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
xref
Reactome:REACT_80330 "APC/C-mediated degradation of cell cycle proteins, Caenorhabditis elegans"
Reactome:REACT_89027 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A, Arabidopsis thaliana"
Reactome:REACT_94347 "APC/C:Cdc20 mediated degradation of Securin, Arabidopsis thaliana"
xref
Reactome:REACT_114974 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A, Oryza sativa"
GO:0031176 : endo-1,4-beta-xylanase activity
def
Catalysis of the endohydrolysis of 1,4-beta-D-xylosidic linkages in xylans.
synonym
"endo-1,4-b-xylanase activity" EXACT []
def
Catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
synonym
"endo-(1,4)-beta-xylanase(1,4)-beta-xylan 4-xylanohydrolase activity" EXACT [EC:3.2.1.8]
GO:0031217 : glucan 1,4-beta-glucosidase activity
def
Catalysis of the hydrolysis of 1,4-linkages in 1,4-beta-D-glucans, to remove successive glucose units.
def
Catalysis of the hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans, to remove successive glucose units.
GO:0031218 : arabinogalactan endo-1,4-beta-galactosidase activity
def
Catalysis of the endohydrolysis of 1,4-beta-D-galactosidic linkages in arabinogalactans.
def
Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in arabinogalactans.
GO:0031295 : T cell costimulation
xref
Reactome:REACT_103203 "CD28 co-stimulation, Schizosaccharomyces pombe"
Reactome:REACT_30717 "Costimulation by the CD28 family, Dictyostelium discoideum"
Reactome:REACT_92669 "CD28 co-stimulation, Dictyostelium discoideum"
xref
Reactome:REACT_34507 "CD28 co-stimulation, Schizosaccharomyces pombe"
GO:0031551 : regulation of brain-derived neurotrophic factor-activated receptor activity
is_a
GO:0043393
GO:0031552 : negative regulation of brain-derived neurotrophic factor-activated receptor activity
is_a
GO:0032091
GO:0031553 : positive regulation of brain-derived neurotrophic factor-activated receptor activity
is_a
GO:0032092
GO:0031581 : hemidesmosome assembly
xref
Reactome:REACT_80480 "Type I hemidesmosome assembly, Drosophila melanogaster"
Reactome:REACT_99612 "Type I hemidesmosome assembly, Caenorhabditis elegans"
xref
Reactome:REACT_112964 "Type I hemidesmosome assembly, Taeniopygia guttata"
Reactome:REACT_113284 "Type I hemidesmosome assembly, Xenopus tropicalis"
GO:0032001 : 1,4-alpha-glucan 6-alpha-glucosyltransferase activity
def
Catalysis of the transfer an alpha-D-glucosyl residue in a 1,4-alpha-D-glucan to the primary hydroxy group of glucose, free or combined in a 1,4-alpha-D-glucan.
def
Catalysis of the transfer an alpha-D-glucosyl residue in a (1->4)-alpha-D-glucan to the primary hydroxy group of glucose, free or combined in a (1->4)-alpha-D-glucan.
GO:0032259 : methylation
xref
Reactome:REACT_82195 "Methylation, Plasmodium falciparum"
GO:0032393 : MHC class I receptor activity
relationship
has_part GO:0042288
GO:0032394 : MHC class Ib receptor activity
relationship
has_part GO:0023029
GO:0032395 : MHC class II receptor activity
relationship
has_part GO:0042289
GO:0032952 : regulation of (1->3)-beta-D-glucan metabolic process
name
regulation of 1,3-beta-D-glucan metabolic process
def
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving beta-1,3 glucans.
name
regulation of (1->3)-beta-D-glucan metabolic process
def
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-beta-D-glucans.
synonym
"regulation of (1->3)-beta-D-glucan metabolism" EXACT []
"regulation of 1,3-beta-D-glucan metabolic process" EXACT []
GO:0032953 : regulation of (1->3)-beta-D-glucan biosynthetic process
name
regulation of 1,3-beta-D-glucan biosynthetic process
def
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta-1,3 glucans.
name
regulation of (1->3)-beta-D-glucan biosynthetic process
def
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.
GO:0033164 : glycolipid 6-alpha-mannosyltransferase activity
def
Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-1,6-D-mannosyl-D-mannose linkage.
def
Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->6)-D-mannosyl-D-mannose linkage.
synonym
"GDP-mannose:oligosaccharide 6-alpha-D-mannosyltransferase activity" EXACT [EC:2.4.1.232]
GO:0033188 : sphingomyelin synthase activity
xref
Reactome:REACT_108706 "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS1], Caenorhabditis elegans"
Reactome:REACT_28466 "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS2], Caenorhabditis elegans"
Reactome:REACT_84431 "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS1], Sus scrofa"
xref
Reactome:REACT_88038 "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS1], Sus scrofa"
GO:0033300 : dehydroascorbic acid transporter activity
xref
Reactome:REACT_111999 "Dehydroascorbate transport across the plasma membrane, Drosophila melanogaster"
Reactome:REACT_112454 "Dehydroascorbate transport across the plasma membrane, Dictyostelium discoideum"
Reactome:REACT_112481 "Dehydroascorbate transport across the plasma membrane, Arabidopsis thaliana"
Reactome:REACT_112492 "Dehydroascorbate transport across the plasma membrane, Caenorhabditis elegans"
Reactome:REACT_112507 "Dehydroascorbate transport across the plasma membrane, Mycobacterium tuberculosis"
Reactome:REACT_113721 "Dehydroascorbate transport across the plasma membrane, Oryza sativa"
Reactome:REACT_114727 "Dehydroascorbate transport across the plasma membrane, Plasmodium falciparum"
GO:0033560 : folate reductase activity
xref
Reactome:REACT_78107 "Folate is reduced to dihydrofolate (DHF), Saccharomyces cerevisiae"
xref
Reactome:REACT_112030 "Folate is reduced to dihydrofolate (DHF), Staphylococcus aureus N315"
Reactome:REACT_112218 "DHF is reduced to tetrahydrofolate (THF), Staphylococcus aureus N315"
Reactome:REACT_114217 "Folate is reduced to dihydrofolate (DHF), Dictyostelium discoideum"
Reactome:REACT_114371 "Folate is reduced to dihydrofolate (DHF), Escherichia coli"
Reactome:REACT_114850 "DHF is reduced to tetrahydrofolate (THF), Escherichia coli"
Reactome:REACT_115392 "DHF is reduced to tetrahydrofolate (THF), Dictyostelium discoideum"
Reactome:REACT_78748 "Folate is reduced to dihydrofolate (DHF), Saccharomyces cerevisiae"
GO:0033723 : fluoroacetaldehyde dehydrogenase activity
is_a
GO:0016620
is_a
GO:0004029
GO:0033745 : L-methionine-(R)-S-oxide reductase activity
synonym
"fRMsr" RELATED [EC:1.8.4.14]
GO:0033778 : 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity
xref
Reactome:REACT_112283 "4-Cholesten-7alpha,27-diol-3-one is 12alpha-hydroxylated to 4-Cholesten-7alpha,12alpha,27-triol-3-one, Dictyostelium discoideum"
Reactome:REACT_113628 "4-Cholesten-7alpha-ol-3-one is 12alpha-hydroxylated to 7-alpha,12-alpha-dihydroxycholest-4-en-3-one, Arabidopsis thaliana"
Reactome:REACT_114278 "4-Cholesten-7alpha,24(S)-diol-3-one is 12alpha-hydroxylated to 4-cholesten-7-alpha,12-alpha,24(S)-triol-3-one, Arabidopsis thaliana"
Reactome:REACT_114416 "4-Cholesten-7alpha-ol-3-one is 12alpha-hydroxylated to 7-alpha,12-alpha-dihydroxycholest-4-en-3-one, Oryza sativa"
Reactome:REACT_114504 "4-Cholesten-7alpha,24(S)-diol-3-one is 12alpha-hydroxylated to 4-cholesten-7-alpha,12-alpha,24(S)-triol-3-one, Dictyostelium discoideum"
Reactome:REACT_114554 "4-Cholesten-7alpha,27-diol-3-one is 12alpha-hydroxylated to 4-Cholesten-7alpha,12alpha,27-triol-3-one, Oryza sativa"
Reactome:REACT_114957 "4-Cholesten-7alpha,24(S)-diol-3-one is 12alpha-hydroxylated to 4-cholesten-7-alpha,12-alpha,24(S)-triol-3-one, Mycobacterium tuberculosis"
Reactome:REACT_115001 "4-Cholesten-7alpha-ol-3-one is 12alpha-hydroxylated to 7-alpha,12-alpha-dihydroxycholest-4-en-3-one, Mycobacterium tuberculosis"
Reactome:REACT_115030 "4-Cholesten-7alpha-ol-3-one is 12alpha-hydroxylated to 7-alpha,12-alpha-dihydroxycholest-4-en-3-one, Dictyostelium discoideum"
Reactome:REACT_115216 "4-Cholesten-7alpha,27-diol-3-one is 12alpha-hydroxylated to 4-Cholesten-7alpha,12alpha,27-triol-3-one, Arabidopsis thaliana"
Reactome:REACT_115313 "4-Cholesten-7alpha,24(S)-diol-3-one is 12alpha-hydroxylated to 4-cholesten-7-alpha,12-alpha,24(S)-triol-3-one, Oryza sativa"
GO:0033781 : cholesterol 24-hydroxylase activity
xref
Reactome:REACT_100082 "Cholesterol is hydroxylated to 24-hydroxycholesterol by CYP46A1, Saccharomyces cerevisiae"
Reactome:REACT_100143 "Cholesterol is hydroxylated to 24-hydroxycholesterol by CYP46A1, Drosophila melanogaster"
Reactome:REACT_87342 "Cholesterol is hydroxylated to 24-hydroxycholesterol by CYP46A1, Arabidopsis thaliana"
Reactome:REACT_90474 "Cholesterol is hydroxylated to 24-hydroxycholesterol by CYP46A1, Mycobacterium tuberculosis"
GO:0033903 : endo-1,3(4)-beta-glucanase activity
synonym
"endo-beta-(1-3)-D-glucanase activity" BROAD [EC:3.2.1.6]
synonym
"endo-beta-(1,3)-D-glucanase activity" BROAD [EC:3.2.1.6]
GO:0033905 : xylan endo-1,3-beta-xylosidase activity
def
Catalysis of the random hydrolysis of 1,3-beta-D-glycosidic linkages in 1,3-beta-D-xylans.
def
Catalysis of the random hydrolysis of (1->3)-beta-D-glycosidic linkages in (1->3)-beta-D-xylans.
GO:0033910 : glucan 1,4-alpha-maltotetraohydrolase activity
def
Catalysis of the hydrolysis of 1,4-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotetraose residues from the non-reducing chain ends.
def
Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotetraose residues from the non-reducing chain ends.
GO:0033912 : 2,6-beta-fructan 6-levanbiohydrolase activity
def
Catalysis of the hydrolysis of 2,6-beta-D-fructofuranan, to remove successive disaccharide residues as levanbiose, i.e. 6-(beta-D-fructofuranosyl)-D-fructose, from the end of the chain.
def
Catalysis of the hydrolysis of (2->6)-beta-D-fructofuranan, to remove successive disaccharide residues as levanbiose, i.e. 6-(beta-D-fructofuranosyl)-D-fructose, from the end of the chain.
GO:0033913 : glucan endo-1,2-beta-glucosidase activity
def
Catalysis of the random hydrolysis of 1,2-glucosidic linkages in 1,2-beta-D-glucans.
def
Catalysis of the random hydrolysis of (1->2)-glucosidic linkages in (1->2)-beta-D-glucans.
GO:0033914 : xylan 1,3-beta-xylosidase activity
def
Catalysis of the hydrolysis of successive xylose residues from the non-reducing termini of 1,3-beta-D-xylans.
def
Catalysis of the hydrolysis of successive xylose residues from the non-reducing termini of (1->3)-beta-D-xylans.
GO:0033915 : mannan 1,2-(1,3)-alpha-mannosidase activity
def
Catalysis of the hydrolysis of 1,2- and 1,3-linkages in mannan, releasing mannose.
def
Catalysis of the hydrolysis of (1->2) and (1->3) linkages in mannan, releasing mannose.
GO:0033916 : beta-agarase activity
def
Catalysis of the hydrolysis of 1,4-beta-D-galactosidic linkages in agarose, giving the tetramer as the predominant product.
def
Catalysis of the hydrolysis of (1->4)-beta-D-galactosidic linkages in agarose, giving the tetramer as the predominant product.
GO:0033919 : glucan 1,3-alpha-glucosidase activity
def
Catalysis of the hydrolysis of terminal 1,3-alpha-D-glucosidic links in 1,3-alpha-D-glucans.
def
Catalysis of the hydrolysis of terminal (1->3)-alpha-D-glucosidic links in 1,3-alpha-D-glucans.
GO:0033921 : capsular-polysaccharide endo-1,3-alpha-galactosidase activity
def
Catalysis of the random hydrolysis of 1,3-alpha-D-galactosidic linkages in Aerobacter aerogenes capsular polysaccharide.
def
Catalysis of the random hydrolysis of (1->3)-alpha-D-galactosidic linkages in Aerobacter aerogenes capsular polysaccharide.
GO:0033923 : glucan 1,6-alpha-isomaltosidase activity
def
Catalysis of the hydrolysis of 1,6-alpha-D-glucosidic linkages in polysaccharides, to remove successive isomaltose units from the non-reducing ends of the chains.
def
Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in polysaccharides, to remove successive isomaltose units from the non-reducing ends of the chains.
GO:0033924 : dextran 1,6-alpha-isomaltotriosidase activity
def
Catalysis of the hydrolysis of 1,6-alpha-D-glucosidic linkages in dextrans, to remove successive isomaltotriose units from the non-reducing ends of the chains.
def
Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in dextrans, to remove successive isomaltotriose units from the non-reducing ends of the chains.
GO:0033927 : glucan 1,4-alpha-maltohexaosidase activity
def
Catalysis of the hydrolysis of 1,4-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltohexaose residues from the non-reducing chain ends.
def
Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltohexaose residues from the non-reducing chain ends.
GO:0033928 : mannan 1,4-mannobiosidase activity
def
Catalysis of the hydrolysis of 1,4-beta-D-mannosidic linkages in 1,4-beta-D-mannans, to remove successive mannobiose residues from the non-reducing chain ends.
def
Catalysis of the hydrolysis of (1->4)-beta-D-mannosidic linkages in (1->4)-beta-D-mannans, to remove successive mannobiose residues from the non-reducing chain ends.
GO:0033929 : blood-group-substance endo-1,4-beta-galactosidase activity
def
Catalysis of the endohydrolysis of 1,4-beta-D-galactosidic linkages in blood group A and B substances.
def
Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in blood group A and B substances.
GO:0033930 : keratan-sulfate endo-1,4-beta-galactosidase activity
def
Catalysis of the endohydrolysis of 1,4-beta-D-galactosidic linkages in keratan sulfate.
def
Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in keratan sulfate.
GO:0033931 : endogalactosaminidase activity
def
Catalysis of the endohydrolysis of 1,4-alpha-D-galactosaminidic linkages in poly(D-galactosamine).
def
Catalysis of the endohydrolysis of (1->4)-alpha-D-galactosaminidic linkages in poly(D-galactosamine).
GO:0033932 : 1,3-alpha-L-fucosidase activity
def
Catalysis of the hydrolysis of 1,3-linkages between alpha-L-fucose and N-acetylglucosamine residues in glycoproteins.
def
Catalysis of the hydrolysis of (1->3) linkages between alpha-L-fucose and N-acetylglucosamine residues in glycoproteins.
GO:0033933 : branched-dextran exo-1,2-alpha-glucosidase activity
def
Catalysis of the hydrolysis of 1,2-alpha-D-glucosidic linkages at the branch points of dextrans and related polysaccharides, producing free D-glucose.
def
Catalysis of the hydrolysis of (1->2)-alpha-D-glucosidic linkages at the branch points of dextrans and related polysaccharides, producing free D-glucose.
GO:0033934 : glucan 1,4-alpha-maltotriohydrolase activity
def
Catalysis of the hydrolysis of 1,4-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotriose residues from the non-reducing chain ends.
def
Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotriose residues from the non-reducing chain ends.
GO:0033935 : oligoxyloglucan beta-glycosidase activity
def
Catalysis of the hydrolysis of 1,4-beta-D-glucosidic links in oligoxyloglucans so as to remove successive isoprimeverose (i.e. alpha-xylo-1,6-beta-D-glucosyl-) residues from the non-reducing chain ends.
def
Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic links in oligoxyloglucans so as to remove successive isoprimeverose (i.e. alpha-xylo-1,6-beta-D-glucosyl-) residues from the non-reducing chain ends.
GO:0033938 : 1,6-alpha-L-fucosidase activity
def
Catalysis of the hydrolysis of 1,6-linkages between alpha-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin.
def
Catalysis of the hydrolysis of (1->6) linkages between alpha-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin.
GO:0033939 : xylan alpha-1,2-glucuronosidase activity
def
Catalysis of the hydrolysis of alpha-D-1,2-(4-O-methyl)glucuronosyl links in the main chain of hardwood xylans.
def
Catalysis of the hydrolysis of alpha-D-(1->2)-(4-O-methyl)glucuronosyl links in the main chain of hardwood xylans.
GO:0033940 : glucuronoarabinoxylan endo-1,4-beta-xylanase activity
def
Catalysis of the endohydrolysis of 1,4-beta-D-xylosyl links in some glucuronoarabinoxylans.
def
Catalysis of the endohydrolysis of (1->4)-beta-D-xylosyl links in some glucuronoarabinoxylans.
GO:0033941 : mannan exo-1,2-1,6-alpha-mannosidase activity
def
Catalysis of the hydrolysis of 1,2-alpha-D- and 1,6-alpha-D- linkages in mannan, releasing D-mannose.
def
Catalysis of the hydrolysis of (1->2)-alpha-D- and (1->6)-alpha-D- linkages in mannan, releasing D-mannose.
GO:0033942 : 4-alpha-D-\{(1->4)-alpha-D-glucano}trehalose trehalohydrolase activity
synonym
"4-alpha-D-{(1,4)-alpha-D-glucano}trehalose glucanohydrolase (trehalose-producing) activity" EXACT [EC:3.2.1.141]
GO:0033943 : galactan 1,3-beta-galactosidase activity
synonym
"galactan (1,3)-beta-D-galactosidase activity" EXACT [EC:3.2.1.145]
GO:0033945 : oligoxyloglucan reducing-end-specific cellobiohydrolase activity
def
Catalysis of the hydrolysis of cellobiose from the reducing end of xyloglucans consisting of a beta-1,4-linked glucan carrying alpha-D-xylosyl groups on O-6 of the glucose residues. To be a substrate, the first residue must be unsubstituted, the second residue may bear a xylosyl group, whether further glycosylated or not, and the third residue, which becomes the new terminus by the action of the enzyme, is preferably xylosylated, but this xylose residue must not be further substituted.
def
Catalysis of the hydrolysis of cellobiose from the reducing end of xyloglucans consisting of a beta-(1->4) linked glucan carrying alpha-D-xylosyl groups on O-6 of the glucose residues. To be a substrate, the first residue must be unsubstituted, the second residue may bear a xylosyl group, whether further glycosylated or not, and the third residue, which becomes the new terminus by the action of the enzyme, is preferably xylosylated, but this xylose residue must not be further substituted.
GO:0033946 : xyloglucan-specific endo-beta-1,4-glucanase activity
def
Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the endohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan.
def
Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the endohydrolysis of (1->4)-beta-D-glucosidic linkages in xyloglucan.
GO:0033948 : fructan beta-(2,1)-fructosidase activity
def
Catalysis of the hydrolysis of terminal, non-reducing 2,1-linked beta-D-fructofuranose residues in fructans.
synonym
"beta-(2-1)-D-fructan fructohydrolase activity" EXACT [EC:3.2.1.153]
"beta-(2-1)-linkage-specific fructan-beta-fructosidase activity" EXACT [EC:3.2.1.153]
"beta-(2-1)fructan exohydrolase activity" EXACT [EC:3.2.1.153]
def
Catalysis of the hydrolysis of terminal, non-reducing (2->1) linked beta-D-fructofuranose residues in fructans.
synonym
"beta-(2,1)-fructan exohydrolase activity" EXACT [EC:3.2.1.153]
"beta-(2,1)-linkage-specific fructan-beta-fructosidase activity" EXACT [EC:3.2.1.153]
GO:0033949 : fructan beta-(2,6)-fructosidase activity
def
Catalysis of the hydrolysis of terminal, non-reducing 2,6-linked beta-D-fructofuranose residues in fructans.
synonym
"beta-(2-6)-fructan exohydrolase activity" EXACT [EC:3.2.1.154]
def
Catalysis of the hydrolysis of terminal, non-reducing (2->6) linked beta-D-fructofuranose residues in fructans.
synonym
"beta-(2,6)-fructan exohydrolase activity" EXACT [EC:3.2.1.154]
GO:0033989 : 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity
xref
Reactome:REACT_110153 "25(S) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA, Mycobacterium tuberculosis"
Reactome:REACT_89457 "25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA, Mycobacterium tuberculosis"
GO:0033994 : glucuronan lyase activity
def
Catalysis of the reaction: (1,4)-beta-D-glucuronan = an oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl end + (1,4)-beta-D-glucuronan. This reaction is the eliminative cleavage of (1->4)-beta-D-glucuronans to give oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl groups at their non-reducing ends. Complete degradation of glucuronans results in the formation of tetrasaccharides.
def
Catalysis of the reaction: (1->4)-beta-D-glucuronan = an oligosaccharide with 4-deoxy-beta-D-gluc-4-enuronosyl end + (1->4)-beta-D-glucuronan. This reaction is the eliminative cleavage of (1->4)-beta-D-glucuronans to give oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl groups at their non-reducing ends. Complete degradation of glucuronans results in the formation of tetrasaccharides.
GO:0034007 : S-linalool synthase activity
synonym
"Lis" RELATED [EC:4.2.3.25]
GO:0034038 : deoxyhypusine synthase activity
xref
Reactome:REACT_33278 "EIF5A + spermidine <=> EIF5A(Dhp) + 1,3-diaminopropane, Plasmodium falciparum"
Reactome:REACT_88614 "EIF5A(Dhp) + 1,3-diaminopropane <=> EIF5A + spermidine, Plasmodium falciparum"
xref
Reactome:REACT_113251 "EIF5A(Dhp) + 1,3-diaminopropane <=> EIF5A + spermidine, Caenorhabditis elegans"
Reactome:REACT_115046 "EIF5A + spermidine <=> EIF5A(Dhp) + 1,3-diaminopropane, Caenorhabditis elegans"
GO:0034130 : toll-like receptor 1 signaling pathway
xref
Reactome:REACT_8005 "Toll Like Receptor TLR1:TLR2 Cascade, Chlamydia trachomatis"
xref
Reactome:REACT_8005 "Toll Like Receptor TLR1:TLR2 Cascade, Homo sapiens"
GO:0034134 : toll-like receptor 2 signaling pathway
xref
Reactome:REACT_101124 "Toll Like Receptor 2 Cascade, Dictyostelium discoideum"
Reactome:REACT_109018 "Toll Like Receptor 2 Cascade, Drosophila melanogaster"
Reactome:REACT_109921 "Toll Like Receptor 2 Cascade, Xenopus tropicalis"
Reactome:REACT_110359 "Toll Like Receptor 2 Cascade, Danio rerio"
Reactome:REACT_29705 "Toll Like Receptor 2 Cascade, Oryza sativa"
Reactome:REACT_30806 "Toll Like Receptor 2 Cascade, Taeniopygia guttata"
Reactome:REACT_31781 "Toll Like Receptor 2 Cascade, Bos taurus"
Reactome:REACT_32312 "Toll Like Receptor 2 Cascade, Saccharomyces cerevisiae"
Reactome:REACT_65361 "Toll Like Receptor 2 Cascade, Gallus gallus"
Reactome:REACT_7980 "Toll Like Receptor 2 Cascade, Homo sapiens"
Reactome:REACT_81077 "Toll Like Receptor 2 Cascade, Canis familiaris"
Reactome:REACT_91964 "Toll Like Receptor 2 Cascade, Mus musculus"
Reactome:REACT_92534 "Toll Like Receptor 2 Cascade, Rattus norvegicus"
Reactome:REACT_92918 "Toll Like Receptor 2 Cascade, Arabidopsis thaliana"
Reactome:REACT_94528 "Toll Like Receptor 2 Cascade, Caenorhabditis elegans"
Reactome:REACT_97650 "Toll Like Receptor 2 Cascade, Sus scrofa"
Reactome:REACT_98284 "Toll Like Receptor 2 Cascade, Schizosaccharomyces pombe"
xref
Reactome:REACT_101124 "Toll Like Receptor 2 (TLR2) Cascade, Dictyostelium discoideum"
Reactome:REACT_109018 "Toll Like Receptor 2 (TLR2) Cascade, Drosophila melanogaster"
Reactome:REACT_109921 "Toll Like Receptor 2 (TLR2) Cascade, Xenopus tropicalis"
Reactome:REACT_110359 "Toll Like Receptor 2 (TLR2) Cascade, Danio rerio"
Reactome:REACT_29705 "Toll Like Receptor 2 (TLR2) Cascade, Oryza sativa"
Reactome:REACT_30806 "Toll Like Receptor 2 (TLR2) Cascade, Taeniopygia guttata"
Reactome:REACT_31781 "Toll Like Receptor 2 (TLR2) Cascade, Bos taurus"
Reactome:REACT_32312 "Toll Like Receptor 2 (TLR2) Cascade, Saccharomyces cerevisiae"
Reactome:REACT_65361 "Toll Like Receptor 2 (TLR2) Cascade, Gallus gallus"
Reactome:REACT_7980 "Toll Like Receptor 2 (TLR2) Cascade, Homo sapiens"
Reactome:REACT_81077 "Toll Like Receptor 2 (TLR2) Cascade, Canis familiaris"
Reactome:REACT_91964 "Toll Like Receptor 2 (TLR2) Cascade, Mus musculus"
Reactome:REACT_92534 "Toll Like Receptor 2 (TLR2) Cascade, Rattus norvegicus"
Reactome:REACT_92918 "Toll Like Receptor 2 (TLR2) Cascade, Arabidopsis thaliana"
Reactome:REACT_94528 "Toll Like Receptor 2 (TLR2) Cascade, Caenorhabditis elegans"
Reactome:REACT_97650 "Toll Like Receptor 2 (TLR2) Cascade, Sus scrofa"
Reactome:REACT_98284 "Toll Like Receptor 2 (TLR2) Cascade, Schizosaccharomyces pombe"
GO:0034188 : apolipoprotein A-I receptor activity
is_a
GO:0034186
relationship
has_part GO:0034186
GO:0034199 : activation of protein kinase A activity
xref
Reactome:REACT_103211 "PKA activation, Caenorhabditis elegans"
xref
Reactome:REACT_111951 "PKA activation, Plasmodium falciparum"
Reactome:REACT_92035 "PKA activation, Caenorhabditis elegans"
GO:0034220 : ion transmembrane transport
xref
Reactome:REACT_105437 "Ion channel transport, Saccharomyces cerevisiae"
Reactome:REACT_28150 "Ion transport by P-type ATPases, Dictyostelium discoideum"
Reactome:REACT_84760 "Ion transport by P-type ATPases, Schizosaccharomyces pombe"
Reactome:REACT_95760 "Ion channel transport, Schizosaccharomyces pombe"
Reactome:REACT_96459 "Ion transport by P-type ATPases, Saccharomyces cerevisiae"
Reactome:REACT_99181 "Ion channel transport, Dictyostelium discoideum"
GO:0034329 : cell junction assembly
xref
Reactome:REACT_33407 "Cell junction organization, Dictyostelium discoideum"
GO:0034332 : adherens junction organization
xref
Reactome:REACT_31798 "Adherens junctions interactions, Sus scrofa"
xref
Reactome:REACT_108185 "Adherens junctions interactions, Sus scrofa"
Reactome:REACT_115366 "Adherens junctions interactions, Drosophila melanogaster"
GO:0034348 : type III interferon receptor activity
is_a
GO:0034347
relationship
has_part GO:0034347
GO:0034407 : cell wall (1->3)-beta-D-glucan metabolic process
name
cell wall 1,3-beta-D-glucan metabolic process
def
The chemical reactions and pathways involving beta-1,3 glucans, compounds composed of glucose residues linked by 1,3-beta-D-glucosidic bonds, found in the walls of cells.
name
cell wall (1->3)-beta-D-glucan metabolic process
def
The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.
synonym
"cell wall 1,3-beta-D-glucan metabolic process" EXACT []
GO:0034409 : ascospore wall (1->3)-beta-D-glucan metabolic process
name
ascospore wall 1,3-beta-D-glucan metabolic process
def
The chemical reactions and pathways involving beta-1,3 glucans, compounds composed of glucose residues linked by 1,3-beta-D-glucosidic bonds, found in the walls of ascospores.
name
ascospore wall (1->3)-beta-D-glucan metabolic process
def
The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.
synonym
"ascospore wall 1,3-beta-D-glucan metabolic process" EXACT []
GO:0034411 : cell wall (1->3)-beta-D-glucan biosynthetic process
name
cell wall 1,3-beta-D-glucan biosynthetic process
def
The chemical reactions and pathways resulting in the formation of 1,3-beta-glucans, compounds composed of glucose residues linked by 1,3-beta-D-glucosidic bonds, found in the walls of cells.
name
cell wall (1->3)-beta-D-glucan biosynthetic process
def
The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.
synonym
"cell wall 1,3-beta-D-glucan biosynthetic process" BROAD []
GO:0034413 : ascospore wall (1->3)-beta-D-glucan biosynthetic process
name
ascospore wall 1,3-beta-D-glucan biosynthetic process
def
The chemical reactions and pathways resulting in the formation of 1,3-beta-glucans, compounds composed of glucose residues linked by 1,3-beta-D-glucosidic bonds, found in the walls of ascospores.
name
ascospore wall (1->3)-beta-D-glucan biosynthetic process
def
The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.
synonym
"ascospore wall 1,3-beta-D-glucan biosynthetic process" BROAD []
GO:0034520 : 2-naphthaldehyde dehydrogenase activity
is_a
GO:0016620
is_a
GO:0004029
GO:0034530 : 4-hydroxymethylsalicyaldehyde dehydrogenase activity
is_a
GO:0016620
is_a
GO:0004029
GO:0034593 : phosphatidylinositol bisphosphate phosphatase activity
is_a
GO:0004437
is_a
GO:0016791
GO:0034594 : phosphatidylinositol trisphosphate phosphatase activity
is_a
GO:0004437
is_a
GO:0016791
GO:0034595 : phosphatidylinositol phosphate 5-phosphatase activity
is_a
GO:0004437
is_a
GO:0016791
GO:0034596 : phosphatidylinositol phosphate 4-phosphatase activity
is_a
GO:0004437
is_a
GO:0016791
GO:0034602 : oxoglutarate dehydrogenase (NAD+) activity
xref
Reactome:REACT_79126 "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+, Saccharomyces cerevisiae"
xref
Reactome:REACT_112439 "alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+, Escherichia coli"
Reactome:REACT_113722 "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+, Oryza sativa"
Reactome:REACT_114766 "alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+, Oryza sativa"
Reactome:REACT_115236 "alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+, Arabidopsis thaliana"
Reactome:REACT_115335 "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+, Escherichia coli"
Reactome:REACT_115419 "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+, Arabidopsis thaliana"
Reactome:REACT_30875 "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+, Saccharomyces cerevisiae"
GO:0034641 : cellular nitrogen compound metabolic process
xref
Reactome:REACT_102044 "Metabolism of amino acids and derivatives, Sus scrofa"
xref
Reactome:REACT_109042 "Metabolism of amino acids and derivatives, Sus scrofa"
GO:0035004 : phosphatidylinositol 3-kinase activity
xref
Reactome:REACT_111081 "Synthesis of PIP3 from PIP2 by PI3K, Homo sapiens"
GO:0035005 : 1-phosphatidylinositol-4-phosphate 3-kinase activity
name
phosphatidylinositol-4-phosphate 3-kinase activity
name
1-phosphatidylinositol-4-phosphate 3-kinase activity
synonym
"phosphatidylinositol-4-phosphate 3-kinase activity" EXACT []
GO:0035299 : inositol pentakisphosphate 2-kinase activity
is_a
GO:0004428
is_a
GO:0016301
GO:0035338 : long-chain fatty-acyl-CoA biosynthetic process
xref
Reactome:REACT_112257 "Synthesis of very long-chain fatty acyl-CoAs, Dictyostelium discoideum"
Reactome:REACT_112844 "Synthesis of very long-chain fatty acyl-CoAs, Plasmodium falciparum"
Reactome:REACT_113523 "Synthesis of very long-chain fatty acyl-CoAs, Mycobacterium tuberculosis"
GO:0035643 : L-DOPA receptor activity
is_a
GO:0072544
relationship
has_part GO:0072544
GO:0035666 : TRIF-dependent toll-like receptor signaling pathway
xref
Reactome:REACT_111135 "TRIF mediated TLR3 signaling, Homo sapiens"
Reactome:REACT_111936 "TRIF mediated TLR3 signaling, Schizosaccharomyces pombe"
Reactome:REACT_112079 "TRIF mediated TLR3 signaling, Caenorhabditis elegans"
Reactome:REACT_112508 "TRIF mediated TLR3 signaling, Taeniopygia guttata"
Reactome:REACT_112658 "TRIF mediated TLR3 signaling, Xenopus tropicalis"
Reactome:REACT_112958 "TRIF mediated TLR3 signaling, Danio rerio"
Reactome:REACT_113472 "TRIF mediated TLR3 signaling, Sus scrofa"
Reactome:REACT_113475 "TRIF mediated TLR3 signaling, Oryza sativa"
Reactome:REACT_113731 "TRIF mediated TLR3 signaling, Gallus gallus"
Reactome:REACT_113758 "TRIF mediated TLR3 signaling, Dictyostelium discoideum"
Reactome:REACT_114089 "TRIF mediated TLR3 signaling, Canis familiaris"
Reactome:REACT_114251 "TRIF mediated TLR3 signaling, Saccharomyces cerevisiae"
Reactome:REACT_114313 "TRIF mediated TLR3 signaling, Drosophila melanogaster"
Reactome:REACT_114629 "TRIF mediated TLR3 signaling, Mus musculus"
Reactome:REACT_114730 "TRIF mediated TLR3 signaling, Bos taurus"
Reactome:REACT_115269 "TRIF mediated TLR3 signaling, Rattus norvegicus"
Reactome:REACT_115453 "TRIF mediated TLR3 signaling, Arabidopsis thaliana"
GO:0035738 : envenomation
def
The process by which venom is forced into an organism by the bite or sting of another organism.
def
The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the manifestation of damage to the bitten organism.
GO:0035821 : modification of morphology or physiology of other organism
is_a
GO:0044419
is_a
GO:0051704
GO:0035872 : nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
xref
Reactome:REACT_102126 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Xenopus tropicalis"
Reactome:REACT_105549 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Gallus gallus"
Reactome:REACT_109121 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Mus musculus"
Reactome:REACT_112945 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Drosophila melanogaster"
Reactome:REACT_75913 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Homo sapiens"
Reactome:REACT_85368 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Rattus norvegicus"
Reactome:REACT_91372 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Danio rerio"
Reactome:REACT_95496 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Bos taurus"
Reactome:REACT_95597 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Taeniopygia guttata"
Reactome:REACT_97582 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Canis familiaris"
Reactome:REACT_99740 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Sus scrofa"
GO:0035892 : modulation of platelet aggregation in other organism
is_a
GO:0044364
GO:0035916 : modulation of calcium channel activity in other organism
is_a
GO:0035821
is_a
GO:0044359
GO:0035917 : negative regulation of calcium channel activity in other organism
is_a
GO:0044362
GO:0052204
GO:0042008 : interleukin-18 receptor activity
is_a
GO:0042007
relationship
has_part GO:0042007
GO:0042010 : interleukin-15 receptor activity
is_a
GO:0042009
relationship
has_part GO:0042009
GO:0042012 : interleukin-16 receptor activity
is_a
GO:0042011
relationship
has_part GO:0042011
GO:0042014 : interleukin-19 receptor activity
is_a
GO:0042013
relationship
has_part GO:0042013
GO:0042016 : interleukin-20 receptor activity
is_a
GO:0042015
relationship
has_part GO:0042015
GO:0042018 : interleukin-22 receptor activity
is_a
GO:0042017
relationship
has_part GO:0042017
GO:0042020 : interleukin-23 receptor activity
is_a
GO:0042019
relationship
has_part GO:0042019
GO:0042124 : 1,3-beta-glucanosyltransferase activity
def
Catalysis of the splitting and linkage of 1,3-beta-glucan molecules, resulting in 1,3-beta-glucan chain elongation.
def
Catalysis of the splitting and linkage of (1->3)-beta-D-glucan molecules, resulting in (1->3)-beta-D-glucan chain elongation.
GO:0042132 : fructose 1,6-bisphosphate 1-phosphatase activity
xref
Reactome:REACT_113175 "D-fructose 1,6-bisphosphate + H2O => D-fructose 6-phosphate + orthophosphate, Escherichia coli"
GO:0042133 : neurotransmitter metabolic process
xref
Reactome:REACT_115498 "Metabolism of Noradrenaline, Dictyostelium discoideum"
GO:0042136 : neurotransmitter biosynthetic process
xref
Reactome:REACT_86523 "Neurotransmitter Clearance In The Synaptic Cleft, Schizosaccharomyces pombe"
Reactome:REACT_88812 "Neurotransmitter Clearance In The Synaptic Cleft, Saccharomyces cerevisiae"
xref
Reactome:REACT_107523 "Neurotransmitter Clearance In The Synaptic Cleft, Schizosaccharomyces pombe"
Reactome:REACT_112396 "Neurotransmitter Clearance In The Synaptic Cleft, Escherichia coli"
Reactome:REACT_115066 "Neurotransmitter Clearance In The Synaptic Cleft, Dictyostelium discoideum"
GO:0042148 : strand invasion
xref
Reactome:REACT_972 "Strand invasion, Homo sapiens"
GO:0042157 : lipoprotein metabolic process
xref
Reactome:REACT_112911 "apolipoprotein(a) + LDL => Lp(a), Xenopus tropicalis"
GO:0042167 : heme catabolic process
xref
Reactome:REACT_114440 "Heme degradation, Caenorhabditis elegans"
GO:0042197 : halogenated hydrocarbon metabolic process
xref
Reactome:REACT_97585 "Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide, Xenopus tropicalis"
GO:0042304 : regulation of fatty acid biosynthetic process
xref
Reactome:REACT_112072 "AMPK inhibits chREBP transcriptional activation activity, Danio rerio"
GO:0042359 : vitamin D metabolic process
xref
Reactome:REACT_101026 "Vitamin D (calciferol) metabolism, Caenorhabditis elegans"
GO:0042392 : sphingosine-1-phosphate phosphatase activity
xref
Reactome:REACT_33509 "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [extracellular], Drosophila melanogaster"
Reactome:REACT_82438 "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - PPAP], Drosophila melanogaster"
xref
Reactome:REACT_113452 "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - SGPP], Schizosaccharomyces pombe"
Reactome:REACT_114519 "sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - SGPP], Saccharomyces cerevisiae"
GO:0042446 : hormone biosynthetic process
xref
Reactome:REACT_102442 "Biosynthesis of amine and peptide hormones, Sus scrofa"
Reactome:REACT_104251 "Biosynthesis of amine and peptide hormones, Arabidopsis thaliana"
Reactome:REACT_105476 "Biosynthesis of amine and peptide hormones, Rattus norvegicus"
Reactome:REACT_107945 "Biosynthesis of amine and peptide hormones, Drosophila melanogaster"
Reactome:REACT_110983 "Biosynthesis of amine and peptide hormones, Canis familiaris"
Reactome:REACT_15314 "Biosynthesis of amine and peptide hormones, Homo sapiens"
Reactome:REACT_32056 "Biosynthesis of amine and peptide hormones, Staphylococcus aureus N315"
Reactome:REACT_33912 "Biosynthesis of amine and peptide hormones, Gallus gallus"
Reactome:REACT_80318 "Biosynthesis of amine and peptide hormones, Danio rerio"
Reactome:REACT_85276 "Biosynthesis of amine and peptide hormones, Bos taurus"
Reactome:REACT_85503 "Biosynthesis of amine and peptide hormones, Taeniopygia guttata"
Reactome:REACT_86029 "Biosynthesis of amine and peptide hormones, Mycobacterium tuberculosis"
Reactome:REACT_87059 "Biosynthesis of amine and peptide hormones, Dictyostelium discoideum"
Reactome:REACT_88717 "Biosynthesis of amine and peptide hormones, Mus musculus"
Reactome:REACT_91733 "Biosynthesis of amine and peptide hormones, Xenopus tropicalis"
Reactome:REACT_92236 "Biosynthesis of amine and peptide hormones, Caenorhabditis elegans"
Reactome:REACT_99547 "Biosynthesis of amine and peptide hormones, Oryza sativa"
GO:0042590 : antigen processing and presentation of exogenous peptide antigen via MHC class I
xref
Reactome:REACT_111119 "Antigen processing-Cross presentation, Homo sapiens"
GO:0042626 : ATPase activity, coupled to transmembrane movement of substances
xref
Reactome:REACT_101912 "LTC4 is exported from the cell, Danio rerio"
Reactome:REACT_102827 "LTC4 is exported from the cell, Caenorhabditis elegans"
Reactome:REACT_103276 "LTC4 is exported from the cell, Drosophila melanogaster"
Reactome:REACT_104723 "LTC4 is exported from the cell, Sus scrofa"
Reactome:REACT_108270 "LTC4 is exported from the cell, Oryza sativa"
Reactome:REACT_15474 "LTC4 is exported from the cell, Homo sapiens"
Reactome:REACT_29118 "LTC4 is exported from the cell, Mus musculus"
Reactome:REACT_29646 "LTC4 is exported from the cell, Taeniopygia guttata"
Reactome:REACT_30914 "LTC4 is exported from the cell, Xenopus tropicalis"
Reactome:REACT_31426 "LTC4 is exported from the cell, Rattus norvegicus"
Reactome:REACT_78784 "LTC4 is exported from the cell, Saccharomyces cerevisiae"
Reactome:REACT_81117 "LTC4 is exported from the cell, Arabidopsis thaliana"
Reactome:REACT_81345 "LTC4 is exported from the cell, Gallus gallus"
Reactome:REACT_81764 "LTC4 is exported from the cell, Schizosaccharomyces pombe"
Reactome:REACT_87167 "LTC4 is exported from the cell, Dictyostelium discoideum"
Reactome:REACT_91861 "LTC4 is exported from the cell, Bos taurus"
Reactome:REACT_94905 "LTC4 is exported from the cell, Canis familiaris"
xref
Reactome:REACT_111189 "ABCA4 mediates retinal transport, Homo sapiens"
Reactome:REACT_15474 "ABCC1 mediates LTC4 export from the cell, Homo sapiens"
GO:0042654 : ecdysis-triggering hormone receptor activity
is_a
GO:0042562
relationship
has_part GO:0042562
GO:0042692 : muscle cell differentiation
xref
Reactome:REACT_113484 "Myogenesis, Caenorhabditis elegans"
GO:0042730 : fibrinolysis
xref
Reactome:REACT_29927 "Dissolution of Fibrin Clot, Caenorhabditis elegans"
GO:0042776 : mitochondrial ATP synthesis coupled proton transport
xref
Reactome:REACT_102259 "Enzyme-bound ATP is released, Taeniopygia guttata"
Reactome:REACT_76939 "Formation of ATP by chemiosmotic coupling, Taeniopygia guttata"
GO:0042781 : 3'-tRNA processing endoribonuclease activity
synonym
"tRNase Z" RELATED [EC:3.1.26.11]
GO:0042787 : protein ubiquitination involved in ubiquitin-dependent protein catabolic process
xref
Reactome:REACT_101051 "Multiubiquitination of APC/C-associated Cdh1, Arabidopsis thaliana"
Reactome:REACT_101618 "Ubiquitination of Cyclin A by APC/C:Cdc20 complex, Arabidopsis thaliana"
Reactome:REACT_107859 "Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex, Arabidopsis thaliana"
Reactome:REACT_34698 "Ubiquitination of Securin by phospho-APC/C:Cdc20 complex, Arabidopsis thaliana"
xref
Reactome:REACT_114376 "Ubiquitination of Cyclin A by APC/C:Cdc20 complex, Oryza sativa"
GO:0042972 : licheninase activity
def
Catalysis of the hydrolysis of 1,4-beta-D-glucosidic linkages in beta-D-glucans containing 1,3- and 1,4-bonds.
def
Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3) and (1->4) bonds.
GO:0042973 : glucan endo-1,3-beta-D-glucosidase activity
def
Catalysis of the hydrolysis of 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans.
def
Catalysis of the hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans.
GO:0042981 : regulation of apoptosis
xref
Reactome:REACT_103151 "Regulation of Apoptosis, Saccharomyces cerevisiae"
Reactome:REACT_91144 "Regulation of Apoptosis, Schizosaccharomyces pombe"
Reactome:REACT_95902 "Regulation of Apoptosis, Dictyostelium discoideum"
GO:0043097 : pyrimidine nucleoside salvage
xref
Reactome:REACT_92837 "Pyrimidine salvage reactions, Sus scrofa"
xref
Reactome:REACT_101113 "Pyrimidine salvage reactions, Sus scrofa"
GO:0043101 : purine-containing compound salvage
xref
Reactome:REACT_103029 "Purine salvage, Sus scrofa"
xref
Reactome:REACT_88584 "Purine salvage, Sus scrofa"
GO:0043123 : positive regulation of I-kappaB kinase/NF-kappaB cascade
xref
Reactome:REACT_24918 "IRAK1 recruits IKK comlex, Homo sapiens"
xref
Reactome:REACT_24918 "IRAK1 recruits IKK complex, Homo sapiens"
GO:0043161 : proteasomal ubiquitin-dependent protein catabolic process
xref
Reactome:REACT_32577 "Degradation multiubiquitinated Cyclin A, Taeniopygia guttata"
GO:0043225 : anion transmembrane-transporting ATPase activity
xref
Reactome:REACT_111162 "The ABCC family mediates organic anion transport, Homo sapiens"
GO:0043252 : sodium-independent organic anion transport
xref
Reactome:REACT_34045 "Transport of organic anions, Gallus gallus"
xref
Reactome:REACT_113843 "Transport of organic anions, Danio rerio"
GO:0043404 : corticotropin-releasing hormone receptor activity
is_a
GO:0051424
relationship
has_part GO:0051424
GO:0043441 : acetoacetic acid biosynthetic process
xref
Reactome:REACT_102599 "Formation of Acetoacetic Acid, Mycobacterium tuberculosis"
Reactome:REACT_103100 "Formation of Acetoacetic Acid, Mus musculus"
Reactome:REACT_103442 "Formation of Acetoacetic Acid, Canis familiaris"
Reactome:REACT_103949 "Formation of Acetoacetic Acid, Gallus gallus"
Reactome:REACT_105058 "Formation of Acetoacetic Acid, Danio rerio"
Reactome:REACT_105676 "Formation of Acetoacetic Acid, Plasmodium falciparum"
Reactome:REACT_110249 "Formation of Acetoacetic Acid, Taeniopygia guttata"
Reactome:REACT_1733 "Formation of Acetoacetic Acid, Homo sapiens"
Reactome:REACT_28148 "Formation of Acetoacetic Acid, Xenopus tropicalis"
Reactome:REACT_30761 "Formation of Acetoacetic Acid, Schizosaccharomyces pombe"
Reactome:REACT_80115 "Formation of Acetoacetic Acid, Oryza sativa"
Reactome:REACT_80443 "Formation of Acetoacetic Acid, Rattus norvegicus"
Reactome:REACT_80856 "Formation of Acetoacetic Acid, Bos taurus"
Reactome:REACT_85987 "Formation of Acetoacetic Acid, Caenorhabditis elegans"
Reactome:REACT_86901 "Formation of Acetoacetic Acid, Sus scrofa"
Reactome:REACT_87123 "Formation of Acetoacetic Acid, Staphylococcus aureus N315"
Reactome:REACT_87774 "Formation of Acetoacetic Acid, Drosophila melanogaster"
Reactome:REACT_94761 "Formation of Acetoacetic Acid, Arabidopsis thaliana"
Reactome:REACT_94961 "Formation of Acetoacetic Acid, Saccharomyces cerevisiae"
Reactome:REACT_95940 "Formation of Acetoacetic Acid, Dictyostelium discoideum"
GO:0043687 : post-translational protein modification
xref
Reactome:REACT_89099 "Post-translational modification: gamma carboxylation and hypusine formation, Plasmodium falciparum"
xref
Reactome:REACT_113592 "Post-translational modification: gamma carboxylation and hypusine formation, Caenorhabditis elegans"
GO:0043733 : DNA-3-methylbase glycosylase activity
name
DNA-3-methyladenine glycosylase III activity
def
Catalysis of the hydrolysis of alkylated DNA; recognizes and removes alkylated 3-methylpurines and pyrimidines by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic or apyrimidinic (AP) site.
name
DNA-3-methylbase glycosylase activity
def
Catalysis of the reaction: DNA containing 3-methylbase + H2O = DNA with abasic site + 3-methylbase. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylpurine or 3-methylpyrimidine base and the deoxyribose sugar to remove the methylated base, leaving an apurinic or apyrimidinic site.
synonym
"DNA-3-methyladenine glycosylase III" RELATED []
GO:0043734 : DNA-N1-methyladenine dioxygenase activity
synonym
"alkB" NARROW []
GO:0043744 : N2-acetyl-L-aminoadipate kinase activity
def
Catalysis of the reaction: N2-acetyl-L-aminoadipate + ATP = N2-acetyl-L-aminoadipyl-delta-phosphate + ADP.
alt_id
GO:0043868
def
Catalysis of the reaction: ATP + N-acetyl-L-aminoadipate = ADP + N-acetyl-L-aminoadipate 5-phosphate.
synonym
"acetylaminoadipate kinase activity" EXACT []
"LysZ" RELATED []
"N-acetyl-L-aminoadipate 5-phosphotransferase activity" EXACT []
"N-acetylaminoadipate kinase activity" EXACT []
GO:0043896 : glucan 1,6-alpha-glucosidase activity
def
Catalysis of the hydrolysis of 1,6-alpha-D-glucosidic linkages in 1,6-alpha-D-glucans and derived oligosaccharides.
def
Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in (1->6)-alpha-D-glucans and derived oligosaccharides.
GO:0043916 : DNA-7-methylguanine glycosylase activity
def
Catalysis of the hydrolysis of alkylated DNA; recognizes and removes the alkylated base 7-methylguanine.
xref
EC:3.2.2.-
def
Catalysis of the reaction: DNA containing 7-methylguanine + H2O = DNA with abasic site + 7-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methylguanine and the deoxyribose sugar to remove the 7-methylguanine, leaving an abasic site.
xref
EC:3.2.2.21
MetaCyc:3.2.2.21-RXN
GO:0043928 : exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
xref
Reactome:REACT_100454 "mRNA Decay by 5' to 3' Exoribonuclease, Rattus norvegicus"
Reactome:REACT_101018 "mRNA Decay by 5' to 3' Exoribonuclease, Caenorhabditis elegans"
Reactome:REACT_99503 "mRNA Decay by 3' to 5' Exoribonuclease, Schizosaccharomyces pombe"
xref
Reactome:REACT_30153 "mRNA Decay by 3' to 5' Exoribonuclease, Schizosaccharomyces pombe"
Reactome:REACT_34492 "mRNA Decay by 5' to 3' Exoribonuclease, Caenorhabditis elegans"
GO:0044245 : polysaccharide digestion
xref
Reactome:REACT_114891 "Digestion of dietary carbohydrate, Escherichia coli"
GO:0044255 : cellular lipid metabolic process
xref
Reactome:REACT_104402 "Fatty acid, triacylglycerol, and ketone body metabolism, Dictyostelium discoideum"
Reactome:REACT_94266 "Fatty acid, triacylglycerol, and ketone body metabolism, Sus scrofa"
xref
Reactome:REACT_112736 "Peroxisomal lipid metabolism, Plasmodium falciparum"
Reactome:REACT_83359 "Fatty acid, triacylglycerol, and ketone body metabolism, Sus scrofa"
Reactome:REACT_89268 "Fatty acid, triacylglycerol, and ketone body metabolism, Dictyostelium discoideum"
GO:0044257 : cellular protein catabolic process
xref
Reactome:REACT_103470 "Degradation of newly synthesized ApoB-48, Bos taurus"
xref
Reactome:REACT_86672 "Degradation of newly synthesized ApoB-48, Bos taurus"
GO:0044267 : cellular protein metabolic process
xref
Reactome:REACT_98814 "Metabolism of proteins, Sus scrofa"
xref
Reactome:REACT_81994 "Metabolism of proteins, Sus scrofa"
GO:0044281 : small molecule metabolic process
xref
Reactome:REACT_111217 "Metabolism, Homo sapiens"
Reactome:REACT_112077 "Metabolism, Xenopus tropicalis"
Reactome:REACT_112140 "Metabolism, Dictyostelium discoideum"
Reactome:REACT_112621 "Metabolism, Mus musculus"
Reactome:REACT_112912 "Metabolism, Arabidopsis thaliana"
Reactome:REACT_113131 "Metabolism, Schizosaccharomyces pombe"
Reactome:REACT_113305 "Metabolism, Canis familiaris"
Reactome:REACT_113457 "Metabolism, Mycobacterium tuberculosis"
Reactome:REACT_113568 "Metabolism, Rattus norvegicus"
Reactome:REACT_113610 "Metabolism, Caenorhabditis elegans"
Reactome:REACT_113934 "Metabolism, Escherichia coli"
Reactome:REACT_114081 "Metabolism, Gallus gallus"
Reactome:REACT_114137 "Metabolism, Sus scrofa"
Reactome:REACT_114421 "Metabolism, Saccharomyces cerevisiae"
Reactome:REACT_114473 "Metabolism, Danio rerio"
Reactome:REACT_114495 "Metabolism, Staphylococcus aureus N315"
Reactome:REACT_114668 "Metabolism, Plasmodium falciparum"
Reactome:REACT_114983 "Metabolism, Drosophila melanogaster"
Reactome:REACT_115063 "Metabolism, Taeniopygia guttata"
Reactome:REACT_115388 "Metabolism, Oryza sativa"
Reactome:REACT_115420 "Metabolism, Bos taurus"
GO:0044284 : mitochondrial crista junction
name
crista junction
def
Tubular structures of relatively uniform size that connect mitochondrial cristae to the inner mitchondrial membrane.
name
mitochondrial crista junction
def
A tubular structure of relatively uniform size that connects a mitochondrial crista to the mitochondrial inner boundary membrane.
synonym
"crista junction" EXACT []
"cristae junction" EXACT []
relationship
part_of GO:0005743
GO:0045007 : depurination
xref
Reactome:REACT_107234 "Recognition and association of DNA glycosylase with site containing an affected purine, Schizosaccharomyces pombe"
xref
Reactome:REACT_99935 "Recognition and association of DNA glycosylase with site containing an affected purine, Schizosaccharomyces pombe"
GO:0045087 : innate immune response
xref
Reactome:REACT_101086 "Innate Immunity Signaling, Bos taurus"
Reactome:REACT_108180 "Innate Immunity Signaling, Arabidopsis thaliana"
Reactome:REACT_110518 "Innate Immunity Signaling, Taeniopygia guttata"
Reactome:REACT_31297 "Innate Immunity Signaling, Xenopus tropicalis"
Reactome:REACT_32992 "Innate Immunity Signaling, Gallus gallus"
Reactome:REACT_6802 "Innate Immunity Signaling, Homo sapiens"
Reactome:REACT_78575 "Innate Immunity Signaling, Canis familiaris"
Reactome:REACT_81815 "Innate Immunity Signaling, Saccharomyces cerevisiae"
Reactome:REACT_81962 "Innate Immunity Signaling, Dictyostelium discoideum"
Reactome:REACT_86987 "Innate Immunity Signaling, Mus musculus"
Reactome:REACT_88681 "Innate Immunity Signaling, Drosophila melanogaster"
Reactome:REACT_90618 "Innate Immunity Signaling, Caenorhabditis elegans"
Reactome:REACT_90753 "Innate Immunity Signaling, Schizosaccharomyces pombe"
Reactome:REACT_94451 "Innate Immunity Signaling, Rattus norvegicus"
Reactome:REACT_95471 "Innate Immunity Signaling, Sus scrofa"
Reactome:REACT_95642 "Innate Immunity Signaling, Oryza sativa"
Reactome:REACT_99610 "Innate Immunity Signaling, Danio rerio"
xref
Reactome:REACT_101086 "Innate Immune System, Bos taurus"
Reactome:REACT_108180 "Innate Immune System, Arabidopsis thaliana"
Reactome:REACT_110518 "Innate Immune System, Taeniopygia guttata"
Reactome:REACT_31297 "Innate Immune System, Xenopus tropicalis"
Reactome:REACT_32992 "Innate Immune System, Gallus gallus"
Reactome:REACT_6802 "Innate Immune System, Homo sapiens"
Reactome:REACT_78575 "Innate Immune System, Canis familiaris"
Reactome:REACT_81815 "Innate Immune System, Saccharomyces cerevisiae"
Reactome:REACT_81962 "Innate Immune System, Dictyostelium discoideum"
Reactome:REACT_86987 "Innate Immune System, Mus musculus"
Reactome:REACT_88681 "Innate Immune System, Drosophila melanogaster"
Reactome:REACT_90618 "Innate Immune System, Caenorhabditis elegans"
Reactome:REACT_90753 "Innate Immune System, Schizosaccharomyces pombe"
Reactome:REACT_94451 "Innate Immune System, Rattus norvegicus"
Reactome:REACT_95471 "Innate Immune System, Sus scrofa"
Reactome:REACT_95642 "Innate Immune System, Oryza sativa"
Reactome:REACT_99610 "Innate Immune System, Danio rerio"
GO:0045153 : electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity
xref
Reactome:REACT_112720 "Electron transfer from ubiquinol to cytochrome c of complex III, Canis familiaris"
Reactome:REACT_112947 "Electron transfer from ubiquinol to cytochrome c of complex III, Drosophila melanogaster"
Reactome:REACT_113468 "Electron transfer from ubiquinol to cytochrome c of complex III, Rattus norvegicus"
Reactome:REACT_113728 "Electron transfer from ubiquinol to cytochrome c of complex III, Bos taurus"
Reactome:REACT_115341 "Electron transfer from ubiquinol to cytochrome c of complex III, Sus scrofa"
GO:0045174 : glutathione dehydrogenase (ascorbate) activity
xref
Reactome:REACT_107653 "Reduction of dehydroascorbate to ascorbate, Caenorhabditis elegans"
xref
Reactome:REACT_114041 "Reduction of dehydroascorbate to ascorbate, Arabidopsis thaliana"
Reactome:REACT_114537 "Reduction of dehydroascorbate to ascorbate, Oryza sativa"
Reactome:REACT_114703 "Reduction of dehydroascorbate to ascorbate, Danio rerio"
GO:0045216 : cell-cell junction organization
xref
Reactome:REACT_114636 "Cell-cell junction organization, Drosophila melanogaster"
GO:0045329 : carnitine biosynthetic process
xref
Reactome:REACT_95542 "Carnitine synthesis, Sus scrofa"
xref
Reactome:REACT_115020 "Carnitine synthesis, Mycobacterium tuberculosis"
Reactome:REACT_115191 "Carnitine synthesis, Staphylococcus aureus N315"
Reactome:REACT_91272 "Carnitine synthesis, Sus scrofa"
GO:0045506 : interleukin-24 receptor activity
is_a
GO:0045510
relationship
has_part GO:0045510
GO:0045507 : interleukin-25 receptor activity
is_a
GO:0045511
relationship
has_part GO:0045511
GO:0045508 : interleukin-26 receptor activity
is_a
GO:0045512
relationship
has_part GO:0045512
GO:0045509 : interleukin-27 receptor activity
is_a
GO:0045513
relationship
has_part GO:0045513
GO:0045786 : negative regulation of cell cycle
xref
Reactome:REACT_112803 "p75NTR negatively regulates cell cycle via SC1, Drosophila melanogaster"
GO:0046134 : pyrimidine nucleoside biosynthetic process
xref
Reactome:REACT_29545 "Pyrimidine biosynthesis, Sus scrofa"
xref
Reactome:REACT_29226 "Pyrimidine biosynthesis, Sus scrofa"
GO:0046135 : pyrimidine nucleoside catabolic process
xref
Reactome:REACT_77811 "Pyrimidine catabolism, Sus scrofa"
xref
Reactome:REACT_113010 "Pyrimidine catabolism, Schizosaccharomyces pombe"
Reactome:REACT_29523 "Pyrimidine catabolism, Sus scrofa"
GO:0046209 : nitric oxide metabolic process
xref
Reactome:REACT_102514 "Metabolism of nitric oxide, Staphylococcus aureus N315"
Reactome:REACT_31937 "Metabolism of nitric oxide, Drosophila melanogaster"
Reactome:REACT_79883 "Metabolism of nitric oxide, Escherichia coli"
Reactome:REACT_86871 "Metabolism of nitric oxide, Dictyostelium discoideum"
xref
Reactome:REACT_114905 "Metabolism of nitric oxide, Taeniopygia guttata"
GO:0046320 : regulation of fatty acid oxidation
xref
Reactome:REACT_102936 "Activated AMPK stimulates fatty-acid oxidation in muscle, Plasmodium falciparum"
xref
Reactome:REACT_114959 "Activated AMPK stimulates fatty-acid oxidation in muscle, Mycobacterium tuberculosis"
GO:0046478 : lactosylceramide metabolic process
def
The chemical reactions and pathways involving lactosylceramides, Gal beta(1,4)Glc beta(1,1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides.
def
The chemical reactions and pathways involving lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides.
GO:0046487 : glyoxylate metabolic process
xref
Reactome:REACT_115415 "Glyoxylate metabolism, Schizosaccharomyces pombe"
Reactome:REACT_115484 "Glyoxylate metabolism, Mycobacterium tuberculosis"
GO:0046557 : glucan endo-1,6-beta-glucosidase activity
def
Catalysis of the random hydrolysis of 1,6-linkages in 1,6-beta-D-glucans.
def
Catalysis of the random hydrolysis of (1->6) linkages in (1->6)-beta-D-glucans.
GO:0046558 : arabinan endo-1,5-alpha-L-arabinosidase activity
def
Catalysis of the endohydrolysis of 1,5-alpha-arabinofuranosidic linkages in 1,5-arabinans.
synonym
"endo-1,5-a-L-arabinanase activity" EXACT []
def
Catalysis of the endohydrolysis of (1->5)-alpha-arabinofuranosidic linkages in (1->5) arabinans.
GO:0046592 : polyamine oxidase activity
xref
Reactome:REACT_78052 "Spermine is oxidized to spermidine, Saccharomyces cerevisiae"
Reactome:REACT_85463 "N-acetylspermine is oxidised to spermidine, Saccharomyces cerevisiae"
Reactome:REACT_86745 "N-acetylspermidine is oxidized to putrescine, Saccharomyces cerevisiae"
xref
Reactome:REACT_108826 "N-acetylspermine is oxidised to spermidine, Saccharomyces cerevisiae"
Reactome:REACT_112199 "N-acetylspermidine is oxidized to putrescine, Drosophila melanogaster"
Reactome:REACT_112853 "N-acetylspermine is oxidised to spermidine, Drosophila melanogaster"
Reactome:REACT_114114 "Spermine is oxidized to spermidine, Caenorhabditis elegans"
Reactome:REACT_114150 "Spermine is oxidized to spermidine, Drosophila melanogaster"
Reactome:REACT_114231 "N-acetylspermine is oxidised to spermidine, Caenorhabditis elegans"
Reactome:REACT_114621 "N-acetylspermidine is oxidized to putrescine, Caenorhabditis elegans"
Reactome:REACT_78001 "N-acetylspermidine is oxidized to putrescine, Saccharomyces cerevisiae"
Reactome:REACT_84703 "Spermine is oxidized to spermidine, Saccharomyces cerevisiae"
GO:0046777 : protein autophosphorylation
xref
Reactome:REACT_80221 "Intermolecular autophosphorylation of ATM within dimeric ATM complexes, Caenorhabditis elegans"
GO:0046853 : inositol or phosphatidylinositol phosphorylation
def
The process of introducing a phosphate group into inositol or a phosphatidylinositol. Inositol is the cyclic alcohol 1,2,3,4,5,6-cyclohexanehexol, which is widely distributed in nature and acts as a growth factor in animals and microorganisms.
subset
gosubset_prok
is_a
GO:0006020
GO:0046835
def
OBSOLETE. The process of introducing a phosphate group into inositol or a phosphatidylinositol. Inositol is the cyclic alcohol 1,2,3,4,5,6-cyclohexanehexol, which is widely distributed in nature and acts as a growth factor in animals and microorganisms.
comment
This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids.
is_obsolete
true
consider
GO:0046854
GO:0052746
GO:0046920 : alpha-(1->3)-fucosyltransferase activity
name
alpha(1,3)-fucosyltransferase activity
def
Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha(1,3)-linkage.
name
alpha-(1->3)-fucosyltransferase activity
def
Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->6) linkage.
synonym
"alpha(1,3)-fucosyltransferase activity" EXACT []
"alpha-(1,3)-fucosyltransferase activity" EXACT []
"alpha-1,3-fucosyltransferase activity" EXACT []
GO:0046921 : alpha-(1->6)-fucosyltransferase activity
name
alpha(1,6)-fucosyltransferase activity
def
Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha(1,6)-linkage.
name
alpha-(1->6)-fucosyltransferase activity
def
Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->6) linkage.
synonym
"alpha(1,6)-fucosyltransferase activity" EXACT []
"alpha-(1,6)-fucosyltransferase activity" EXACT []
"alpha-1,6-fucosyltransferase activity" EXACT []
GO:0046933 : hydrogen ion transporting ATP synthase activity, rotational mechanism
xref
Reactome:REACT_94502 "ATP is synthesized from ADP and Pi by ATPase, Taeniopygia guttata"
GO:0046934 : phosphatidylinositol-4,5-bisphosphate 3-kinase activity
xref
Reactome:REACT_100772 "PI3K converts Phosphatidylinositol-4,5-bisphosphate to Phosphatidylinositol-3,4,5-trisphosphate, Xenopus tropicalis"
Reactome:REACT_110694 "PI3K converts Phosphatidylinositol-4,5-bisphosphate to Phosphatidylinositol-3,4,5-trisphosphate, Taeniopygia guttata"
Reactome:REACT_12636 "PI3K converts Phosphatidylinositol-4,5-bisphosphate to Phosphatidylinositol-3,4,5-trisphosphate, Homo sapiens"
Reactome:REACT_32593 "PI3K converts Phosphatidylinositol-4,5-bisphosphate to Phosphatidylinositol-3,4,5-trisphosphate, Rattus norvegicus"
Reactome:REACT_80332 "PI3K converts Phosphatidylinositol-4,5-bisphosphate to Phosphatidylinositol-3,4,5-trisphosphate, Canis familiaris"
Reactome:REACT_83904 "PI3K converts Phosphatidylinositol-4,5-bisphosphate to Phosphatidylinositol-3,4,5-trisphosphate, Bos taurus"
Reactome:REACT_84814 "PI3K converts Phosphatidylinositol-4,5-bisphosphate to Phosphatidylinositol-3,4,5-trisphosphate, Mus musculus"
Reactome:REACT_90594 "PI3K converts Phosphatidylinositol-4,5-bisphosphate to Phosphatidylinositol-3,4,5-trisphosphate, Gallus gallus"
Reactome:REACT_92080 "PI3K catalyses the phosphorylation of PIP2 to PIP3, Drosophila melanogaster"
Reactome:REACT_94133 "PI3K converts Phosphatidylinositol-4,5-bisphosphate to Phosphatidylinositol-3,4,5-trisphosphate, Danio rerio"
is_a
GO:0035004
xref
Reactome:REACT_100772 "PIK3 converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3), Xenopus tropicalis"
Reactome:REACT_110694 "PIK3 converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3), Taeniopygia guttata"
Reactome:REACT_115133 "PI3K phosphorylates PIP2 to PIP3, Xenopus tropicalis"
Reactome:REACT_12636 "PIK3 converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3), Homo sapiens"
Reactome:REACT_32593 "PIK3 converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3), Rattus norvegicus"
Reactome:REACT_80332 "PIK3 converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3), Canis familiaris"
Reactome:REACT_83904 "PIK3 converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3), Bos taurus"
Reactome:REACT_84814 "PIK3 converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3), Mus musculus"
Reactome:REACT_90594 "PIK3 converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3), Gallus gallus"
Reactome:REACT_94133 "PIK3 converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3), Danio rerio"
is_a
GO:0052813
GO:0046950 : cellular ketone body metabolic process
xref
Reactome:REACT_84796 "Ketone body metabolism, Sus scrofa"
xref
Reactome:REACT_107371 "Ketone body metabolism, Sus scrofa"
GO:0046951 : ketone body biosynthetic process
xref
Reactome:REACT_32527 "Synthesis of Ketone Bodies, Sus scrofa"
xref
Reactome:REACT_92114 "Synthesis of Ketone Bodies, Sus scrofa"
GO:0046952 : ketone body catabolic process
xref
Reactome:REACT_33641 "Utilization of Ketone Bodies, Oryza sativa"
Reactome:REACT_79469 "Utilization of Ketone Bodies, Arabidopsis thaliana"
Reactome:REACT_96439 "Utilization of Ketone Bodies, Sus scrofa"
xref
Reactome:REACT_33137 "Utilization of Ketone Bodies, Sus scrofa"
GO:0047057 : vitamin-K-epoxide reductase (warfarin-sensitive) activity
xref
Reactome:REACT_85801 "vitamin K epoxide -> vitamin K hydroquinone, Sus scrofa"
xref
Reactome:REACT_106636 "vitamin K epoxide -> vitamin K hydroquinone, Sus scrofa"
Reactome:REACT_113699 "vitamin K epoxide -> vitamin K hydroquinone, Drosophila melanogaster"
GO:0047069 : 7,8-dihydroxykynurenate 8,8a-dioxygenase activity
synonym
"7,8-dihydroxykynurenate:oxygen 8,8alpha-oxidoreductase (decyclizing)" EXACT [EC:1.13.11.10]
GO:0047106 : 4-hydroxyphenylacetaldehyde dehydrogenase activity
is_a
GO:0016620
is_a
GO:0004029
GO:0047107 : gamma-guanidinobutyraldehyde dehydrogenase activity
is_a
GO:0016620
is_a
GO:0004029
GO:0047207 : 1,2-beta-fructan 1F-fructosyltransferase activity
def
Catalysis of the reaction: (1,2-beta-D-fructosyl)(n) + (1,2-beta-D-fructosyl)(m) = (1,2-beta-D-fructosyl)(n+1) + (1,2-beta-D-fructosyl)(m-1).
def
Catalysis of the reaction: [(1->2)-beta-D-fructosyl](n) + [(1->2)-beta-D-fructosyl](m) = [(1->2)-beta-D-fructosyl](n+1) + [(1->2)-beta-D-fructosyl](m-1).
GO:0047252 : beta-mannosylphosphodecaprenol-mannooligosaccharide 6-mannosyltransferase activity
def
Catalysis of the reaction: 1,6-alpha-D-mannosyloligodaccharide + beta-D-mannosylphosphodecaprenol = 1,6-alpha-D-mannosyl-1,6-alpha-D-mannosyl-oligosaccharide + decaprenol phosphate.
def
Catalysis of the reaction: (1->6)-alpha-D-mannosyloligosaccharide + beta-D-mannosylphosphodecaprenol = (1->6)-alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-oligosaccharide + decaprenol phosphate.
GO:0047255 : galactogen 6-beta-galactosyltransferase activity
synonym
"beta-(1-6)-D-galactosyltransferase activity" EXACT [EC:2.4.1.205]
synonym
"beta-(1,6)-D-galactosyltransferase activity" EXACT [EC:2.4.1.205]
GO:0047264 : heteroglycan alpha-mannosyltransferase activity
def
Catalysis of the reactions: heteroglycan + GDP-mannose = 1,2-alpha-D-mannosylheteroglycan + GDP, and heteroglycan + GDP-mannose = 1,3-alpha-D-mannosylheteroglycan + GDP.
xref
MetaCyc:2.4.1.48-RXN
def
Catalysis of the reaction: heteroglycan + GDP-mannose = alpha-D-mannosylheteroglycan + GDP.
GO:0047290 : (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity
synonym
"neuac-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase activity" EXACT [EC:2.4.99.7]
GO:0047309 : dihydroxyphenylalanine transaminase activity
synonym
"dopa aminotransferase activity" EXACT [EC:2.6.1.49]
GO:0047360 : undecaprenyl-phosphate galactose phosphotransferase activity
synonym
"Poly(isoprenol)-phosphate galactosephosphotransferase activity" EXACT [EC:2.7.8.6]
GO:0047372 : acylglycerol lipase activity
xref
Reactome:REACT_86016 "2-AG hydrolysis to arachidonate by MAGL, Dictyostelium discoideum"
Reactome:REACT_95587 "2-acylglycerol + H2O -> glycerol + fatty acid, Saccharomyces cerevisiae"
xref
Reactome:REACT_112247 "Digestion of diacylglycerols by extracellular PTL:colipase, Xenopus tropicalis"
Reactome:REACT_112520 "DAG is metabolized by DAGL to 2-AG, Arabidopsis thaliana"
Reactome:REACT_112608 "2-AG hydrolysis to arachidonate by MAGL, Arabidopsis thaliana"
Reactome:REACT_112674 "DAG is metabolized by DAGL to 2-AG, Oryza sativa"
Reactome:REACT_113210 "Digestion of triacylglycerols by extracellular PTL:colipase, Gallus gallus"
Reactome:REACT_113735 "2-acylglycerol + H2O -> glycerol + fatty acid, Arabidopsis thaliana"
Reactome:REACT_114438 "2-acylglycerol + H2O -> glycerol + fatty acid, Staphylococcus aureus N315"
Reactome:REACT_114496 "Digestion of triacylglycerols by extracellular PTL:colipase, Xenopus tropicalis"
Reactome:REACT_114762 "Digestion of diacylglycerols by extracellular PTL:colipase, Gallus gallus"
Reactome:REACT_114842 "2-acylglycerol + H2O -> glycerol + fatty acid, Oryza sativa"
Reactome:REACT_115057 "2-AG hydrolysis to arachidonate by MAGL, Staphylococcus aureus N315"
Reactome:REACT_115200 "2-AG hydrolysis to arachidonate by MAGL, Oryza sativa"
Reactome:REACT_115325 "DAG is metabolized by DAGL to 2-AG, Caenorhabditis elegans"
Reactome:REACT_81812 "2-AG hydrolysis to arachidonate by MAGL, Dictyostelium discoideum"
Reactome:REACT_94131 "2-acylglycerol + H2O -> glycerol + fatty acid, Saccharomyces cerevisiae"
GO:0047379 : ADP-dependent short-chain-acyl-CoA hydrolase activity
synonym
"propionyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.18]
"propionyl-CoA hydrolase activity" EXACT [EC:3.1.2.18]
"propionyl-CoA thioesterase activity" EXACT [EC:3.1.2.18]
"short-chain acyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.18]
"short-chain acyl-CoA hydrolase activity" EXACT [EC:3.1.2.18]
"short-chain acyl-CoA thioesterase activity" EXACT [EC:3.1.2.18]
synonym
"ADP-dependent propionyl coenzyme A hydrolase activity" NARROW [EC:3.1.2.18]
"ADP-dependent propionyl-CoA hydrolase activity" NARROW [EC:3.1.2.18]
"ADP-dependent propionyl-CoA thioesterase activity" NARROW [EC:3.1.2.18]
"ADP-dependent short-chain acyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.18]
"ADP-dependent short-chain acyl-CoA hydrolase activity" EXACT [EC:3.1.2.18]
"ADP-dependent short-chain acyl-CoA thioesterase activity" EXACT [EC:3.1.2.18]
GO:0047380 : ADP-dependent medium-chain-acyl-CoA hydrolase activity
synonym
"medium-chain acyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.19]
"medium-chain acyl-CoA hydrolase activity" EXACT [EC:3.1.2.19]
"medium-chain acyl-thioester hydrolase activity" EXACT [EC:3.1.2.19]
"medium-chain hydrolase activity" EXACT [EC:3.1.2.19]
"myristoyl-CoA thioesterase activity" EXACT [EC:3.1.2.19]
synonym
"ADP-dependent medium-chain acyl coenzyme A hydrolase activity" EXACT [EC:3.1.2.19]
"ADP-dependent medium-chain acyl-CoA hydrolase activity" EXACT [EC:3.1.2.19]
"ADP-dependent medium-chain acyl-thioester hydrolase activity" EXACT [EC:3.1.2.19]
"ADP-dependent medium-chain hydrolase activity" EXACT [EC:3.1.2.19]
"ADP-dependent myristoyl-CoA thioesterase activity" NARROW [EC:3.1.2.19]
GO:0047470 : (1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase activity
def
Catalysis of the reaction: 4-(1,4-alpha-D-glucosyl)(n-1)-D-glucose = 1-alpha-D-(1,4-alpha-D-glucosyl)(n-1)-alpha-D-glucopyranoside.
def
Catalysis of the reaction: 4-[(1->4)-alpha-D-glucosyl](n-1)-D-glucose = 1-alpha-D-[(1->4)-alpha-D-glucosyl](n-1)-alpha-D-glucopyranoside.
GO:0047514 : 1,3-beta-D-glucan phosphorylase activity
def
Catalysis of the reaction: 1,3-beta-D-glucosyl(n) + phosphate = 1,3-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate; substrates include laminarin.
def
Catalysis of the reaction: [(1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate; substrates include laminarin.
GO:0047515 : 1,3-beta-oligoglucan phosphorylase activity
def
Catalysis of the reaction: oligomeric 1,3-beta-D-glucosyl(n) + phosphate = 1,3-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate.
def
Catalysis of the reaction: [oligomeric (1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.
GO:0047517 : 1,4-beta-D-xylan synthase activity
def
Catalysis of the reaction: UDP-D-xylose + 1,4-beta-D-xylan(n) = UDP + 1,4-beta-D-xylan(n+1).
def
Catalysis of the reaction: UDP-D-xylose + [(1->4)-beta-D-xylan](n) = UDP + [(1->4)-beta-D-xylan](n+1).
GO:0047536 : 2-aminoadipate transaminase activity
xref
Reactome:REACT_112934 "alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate, Escherichia coli"
Reactome:REACT_113111 "alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate, Staphylococcus aureus N315"
Reactome:REACT_113427 "alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate, Saccharomyces cerevisiae"
Reactome:REACT_114940 "alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate, Schizosaccharomyces pombe"
GO:0047551 : 2-oxoaldehyde dehydrogenase (NAD) activity
is_a
GO:0016620
is_a
GO:0004029
GO:0047552 : 2-oxoaldehyde dehydrogenase (NADP+) activity
is_a
GO:0016620
is_a
GO:0033721
GO:0047555 : 3',5'-cyclic-GMP phosphodiesterase activity
xref
Reactome:REACT_115190 "cGMP is degraded by PDEs, Plasmodium falciparum"
GO:0047560 : 3-dehydrosphinganine reductase activity
xref
Reactome:REACT_106626 "3-ketosphinganine + NADPH + H+ => sphinganine + NADP+, Schizosaccharomyces pombe"
Reactome:REACT_34769 "3-ketosphinganine + NADPH + H+ => sphinganine + NADP+, Mycobacterium tuberculosis"
Reactome:REACT_80028 "3-ketosphinganine + NADPH + H+ => sphinganine + NADP+, Dictyostelium discoideum"
Reactome:REACT_82369 "3-ketosphinganine + NADPH + H+ => sphinganine + NADP+, Saccharomyces cerevisiae"
xref
Reactome:REACT_104625 "3-ketosphinganine + NADPH + H+ => sphinganine + NADP+, Dictyostelium discoideum"
GO:0047617 : acyl-CoA hydrolase activity
alt_id
GO:0008778
GO:0016291
GO:0016292
synonym
"acyl-CoA thioesterase activity" EXACT []
"acyl-CoA thioesterase I activity" NARROW []
"acyl-CoA thioesterase II activity" NARROW []
"acyl-CoA thiolesterase activity" EXACT []
xref
EC:3.1.2.-
GO:0047657 : alpha-1,3-glucan synthase activity
synonym
"UDP-glucose:alpha-D-(1-3)-glucan 3-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.183]
"UDPglucose:alpha-D-(1-3)-glucan 3-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.183]
synonym
"UDP-glucose:alpha-D-(1->3)-glucan 3-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.183]
"UDPglucose:alpha-D-(1->3)-glucan 3-alpha-D-glucosyltransferase activity" EXACT [EC:2.4.1.183]
GO:0047683 : aryl-aldehyde dehydrogenase (NADP+) activity
is_a
GO:0016620
is_a
GO:0033721
GO:0047712 : Cypridina-luciferin 2-monooxygenase activity
synonym
"cypridina-type luciferase activity" EXACT [EC:1.13.12.6]
GO:0047787 : delta4-3-oxosteroid 5beta-reductase activity
synonym
"delta-4-3-oxosteroid 5-beta-reductase activity" EXACT []
synonym
"delta4-3-oxosteroid 5-beta-reductase activity" EXACT []
GO:0047911 : galacturan 1,4-alpha-galacturonidase activity
def
Catalysis of the reaction: 1,4-alpha-D-galacturonide(n) + H2O = 1,4-alpha-D-galacturonide(n-1) + D-galacturonate.
synonym
"galacturan 1,4-a-galacturonidase activity" EXACT []
def
Catalysis of the reaction: [(1->4)-alpha-D-galacturonide](n) + H2O = [(1->4)-alpha-D-galacturonide](n-1) + D-galacturonate.
synonym
"galacturan alpha-1,4-galacturonidase activity" EXACT []
GO:0047962 : glycine N-benzoyltransferase activity
xref
Reactome:REACT_103512 "benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A, Sus scrofa"
Reactome:REACT_87885 "salicylate-CoA + glycine => salicyluric acid + Coenzyme A, Sus scrofa"
xref
Reactome:REACT_100176 "benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A, Sus scrofa"
Reactome:REACT_81307 "salicylate-CoA + glycine => salicyluric acid + Coenzyme A, Sus scrofa"
GO:0047969 : glyoxylate oxidase activity
xref
Reactome:REACT_112040 "Conversion of glyoxylate to oxalate, Dictyostelium discoideum"
Reactome:REACT_112588 "Conversion of glyoxylate to oxalate, Arabidopsis thaliana"
Reactome:REACT_112724 "Conversion of glyoxylate to oxalate, Drosophila melanogaster"
Reactome:REACT_113190 "Conversion of glyoxylate to oxalate, Escherichia coli"
Reactome:REACT_113242 "Conversion of glyoxylate to oxalate, Mycobacterium tuberculosis"
Reactome:REACT_114948 "Conversion of glyoxylate to oxalate, Oryza sativa"
GO:0048011 : nerve growth factor receptor signaling pathway
xref
Reactome:REACT_34527 "Signalling by NGF, Sus scrofa"
xref
Reactome:REACT_112151 "Signalling by NGF, Plasmodium falciparum"
Reactome:REACT_112852 "p75 NTR receptor-mediated signalling, Dictyostelium discoideum"
Reactome:REACT_33617 "Signalling by NGF, Sus scrofa"
GO:0048106 : establishment of thoracic bristle planar orientation
name
establishment of body bristle planar orientation
name
establishment of thoracic bristle planar orientation
synonym
"establishment of body bristle planar orientation" EXACT [GOC:bf]
GO:0048205 : COPI coating of Golgi vesicle
xref
Reactome:REACT_33523 "COPI Mediated Transport, Schizosaccharomyces pombe"
xref
Reactome:REACT_34581 "COPI Mediated Transport, Schizosaccharomyces pombe"
GO:0048208 : COPII vesicle coating
xref
Reactome:REACT_104797 "COPII (Coat Protein 2) Mediated Vesicle Transport, Plasmodium falciparum"
Reactome:REACT_109280 "COPII (Coat Protein 2) Mediated Vesicle Transport, Caenorhabditis elegans"
xref
Reactome:REACT_83562 "COPII (Coat Protein 2) Mediated Vesicle Transport, Plasmodium falciparum"
GO:0048718 : cibarial fish-trap bristle morphogenesis
name
fish trap bristle morphogenesis
def
The process in which the anatomical structures of a fish trap bristle are generated and organized.
name
cibarial fish-trap bristle morphogenesis
def
The process in which the anatomical structures of a cibarial fish-trap bristle are generated and organized. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium.
synonym
"fish trap bristle morphogenesis" RELATED [GOC:rc]
GO:0048725 : cibarial fish-trap bristle development
name
fish trap bristle development
def
The process whose specific outcome is the progression of the fish trap bristle over time, from its formation to the mature structure.
name
cibarial fish-trap bristle development
def
The process whose specific outcome is the progression of the cibarial fish-trap bristle over time, from its formation to the mature structure. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium.
synonym
"fish-trap bristle development" EXACT [GOC:rc]
GO:0050061 : long-chain-aldehyde dehydrogenase activity
def
Catalysis of the reaction: a long-chain aldehyde + NAD+ = a long-chain carboxylate + NADH + H+.
is_a
GO:0016620
def
Catalysis of the reaction: a long-chain aldehyde + NAD+ = a long-chain carboxylate + NADH + H+. A long-chain aldehyde is one with more than 12 carbons.
is_a
GO:0004029
GO:0050145 : nucleoside phosphate kinase activity
xref
Reactome:REACT_34318 "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP [CMPK1], Caenorhabditis elegans"
Reactome:REACT_79145 "(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP [CMPK1], Caenorhabditis elegans"
Reactome:REACT_85344 "dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK], Caenorhabditis elegans"
xref
Reactome:REACT_112506 "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP [CMPK1], Escherichia coli"
Reactome:REACT_112761 "(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP [CMPK1], Escherichia coli"
Reactome:REACT_83351 "(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP [CMPK1], Caenorhabditis elegans"
Reactome:REACT_88127 "dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK], Caenorhabditis elegans"
Reactome:REACT_90614 "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP [CMPK1], Caenorhabditis elegans"
GO:0050197 : phytanate-CoA ligase activity
xref
Reactome:REACT_113403 "phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate, Taeniopygia guttata"
Reactome:REACT_114248 "phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate, Saccharomyces cerevisiae"
GO:0050248 : Renilla-luciferin 2-monooxygenase activity
synonym
"renilla-type luciferase activity" EXACT [EC:1.13.12.5]
GO:0050269 : coniferyl-aldehyde dehydrogenase activity
is_a
GO:0016620
is_a
GO:0004030
GO:0050291 : sphingosine N-acyltransferase activity
xref
Reactome:REACT_115485 "sphinganine + stearyl-CoA => dihydroceramide + CoASH, Drosophila melanogaster"
GO:0050294 : steroid sulfotransferase activity
xref
Reactome:REACT_112914 "beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP, Danio rerio"
Reactome:REACT_115144 "beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP, Gallus gallus"
GO:0050327 : testosterone 17-beta-dehydrogenase (NAD+) activity
xref
Reactome:REACT_78645 "Reduction of androstenedione to testosterone, Caenorhabditis elegans"
xref
Reactome:REACT_112435 "Reduction of androstenedione to testosterone, Mycobacterium tuberculosis"
GO:0050353 : trimethyllysine dioxygenase activity
xref
Reactome:REACT_102702 "trimethyllysine + alpha-ketoglutarate + O2 => beta-hydroxy-trimethyllysine + succinate + CO2, Bos taurus"
Reactome:REACT_105506 "trimethyllysine + alpha-ketoglutarate + O2 => beta-hydroxy-trimethyllysine + succinate + CO2, Saccharomyces cerevisiae"
xref
Reactome:REACT_97973 "trimethyllysine + alpha-ketoglutarate + O2 => beta-hydroxy-trimethyllysine + succinate + CO2, Bos taurus"
GO:0050390 : valine decarboxylase activity
synonym
"l-valine carboxy-lyase activity" EXACT [EC:4.1.1.14]
GO:0050397 : Watasenia-luciferin 2-monooxygenase activity
synonym
"watasenia-type luciferase activity" EXACT [EC:1.13.12.8]
GO:0050427 : 3'-phosphoadenosine 5'-phosphosulfate metabolic process
xref
Reactome:REACT_105535 "Cytosolic sulfonation of small molecules, Schizosaccharomyces pombe"
Reactome:REACT_29071 "Cytosolic sulfonation of small molecules, Saccharomyces cerevisiae"
xref
Reactome:REACT_114637 "Cytosolic sulfonation of small molecules, Escherichia coli"
GO:0050428 : 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process
xref
Reactome:REACT_107642 "Formation of PAPS, Saccharomyces cerevisiae"
Reactome:REACT_97279 "Formation of PAPS, Schizosaccharomyces pombe"
xref
Reactome:REACT_114402 "Formation of PAPS, Escherichia coli"
GO:0050442 : 3-propylmalate synthase activity
synonym
"n-propylmalate synthase activity" EXACT [EC:2.3.3.12]
GO:0050471 : uracilylalanine synthase activity
synonym
"willardiine synthase activity" EXACT [EC:2.5.1.53]
GO:0050500 : 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase activity
def
Catalysis of the reaction: phosphate + beta-D-galactopyranosyl-(1,3)-N-acetyl-D-glucosamine = N-acetyl-D-glucosamine + alpha-D-galactopyranose 1-phosphate.
synonym
"1,3-b-galactosyl-N-acetylhexosamine phosphorylase activity" EXACT []
def
Catalysis of the reaction: phosphate + beta-D-galactopyranosyl-(1->3)-N-acetyl-D-glucosamine = N-acetyl-D-glucosamine + alpha-D-galactopyranose 1-phosphate.
synonym
"beta-1,3-galactosyl-N-acetylhexosamine phosphorylase activity" EXACT []
"beta-D-galactopyranosyl-(1,3)-N-acetyl-D-hexosamine:phosphate galactosyltransferase activity" EXACT [EC:2.4.1.211]
GO:0050501 : hyaluronan synthase activity
def
Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl(1,4)beta-D-glucuronosyl(1,3)](n) + 2n UDP.
synonym
"HAS activity" EXACT [EC:2.4.1.212]
def
Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)](n) + 2n UDP.
synonym
"alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1,3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1,4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity" EXACT [EC:2.4.1.212]
"HAS activity" BROAD [EC:2.4.1.212]
GO:0050512 : lactosylceramide 4-alpha-galactosyltransferase activity
synonym
"Gal-beta-1-4Glc-beta-1-Cer alpha-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.228]
"galbeta1-4Glcbeta1-Cer alpha1,4-galactosyltransferase activity" EXACT [EC:2.4.1.228]
synonym
"Gal-beta-(1,4)-Glc-beta-1-Cer alpha-(1,4)-galactosyltransferase activity" EXACT [EC:2.4.1.228]
"Gal-beta-1,4-Glc-beta-1-Cer alpha-1,4-galactosyltransferase activity" EXACT [EC:2.4.1.228]
GO:0050513 : glycoprotein 2-beta-D-xylosyltransferase activity
synonym
"beta1,2-xylosyltransferase activity" EXACT [EC:2.4.2.38]
synonym
"1,2-beta-xylosyltransferase activity" EXACT [EC:2.4.2.38]
GO:0050567 : glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
synonym
"glu-tRNA(gln) amidotransferase activity" EXACT [EC:6.3.5.-]
GO:0050569 : glycolaldehyde dehydrogenase activity
is_a
GO:0016620
is_a
GO:0004029
GO:0050613 : delta14-sterol reductase activity
xref
Reactome:REACT_113353 "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR], Drosophila melanogaster"
Reactome:REACT_115123 "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2], Drosophila melanogaster"
GO:0050614 : delta24-sterol reductase activity
xref
Reactome:REACT_33198 "Reduction of desmosterol to cholesterol, Caenorhabditis elegans"
GO:0050632 : propionyl-CoA C2-trimethyltridecanoyltransferase activity
xref
Reactome:REACT_29142 "3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA, Sus scrofa"
Reactome:REACT_81247 "Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA, Drosophila melanogaster"
Reactome:REACT_81883 "3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA, Drosophila melanogaster"
Reactome:REACT_88640 "Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA, Drosophila melanogaster"
xref
Reactome:REACT_106600 "3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA, Sus scrofa"
GO:0050633 : acetyl-CoA C-myristoyltransferase activity
xref
Reactome:REACT_100645 "3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA, Caenorhabditis elegans"
Reactome:REACT_100898 "3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA, Escherichia coli"
Reactome:REACT_106290 "3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA, Escherichia coli"
Reactome:REACT_110772 "3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA, Escherichia coli"
Reactome:REACT_34047 "3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA, Escherichia coli"
Reactome:REACT_51199 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Bos taurus"
Reactome:REACT_79953 "3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA, Caenorhabditis elegans"
Reactome:REACT_87877 "3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA, Escherichia coli"
Reactome:REACT_94959 "3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA, Escherichia coli"
xref
Reactome:REACT_103468 "3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA, Caenorhabditis elegans"
Reactome:REACT_90562 "3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA, Caenorhabditis elegans"
Reactome:REACT_99776 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Bos taurus"
GO:0050772 : positive regulation of axonogenesis
xref
Reactome:REACT_112731 "Axonal growth stimulation, Danio rerio"
Reactome:REACT_113936 "Axonal growth stimulation, Rattus norvegicus"
GO:0050796 : regulation of insulin secretion
xref
Reactome:REACT_79002 "Regulation of Insulin Secretion, Plasmodium falciparum"
xref
Reactome:REACT_114254 "Regulation of Insulin Secretion, Oryza sativa"
Reactome:REACT_114277 "Regulation of Insulin Secretion, Saccharomyces cerevisiae"
Reactome:REACT_114911 "Regulation of Insulin Secretion, Arabidopsis thaliana"
Reactome:REACT_115218 "Regulation of Insulin Secretion, Schizosaccharomyces pombe"
GO:0050852 : T cell receptor signaling pathway
xref
Reactome:REACT_112881 "TCR signaling, Plasmodium falciparum"
GO:0050999 : regulation of nitric-oxide synthase activity
xref
Reactome:REACT_104392 "eNOS activation and regulation, Escherichia coli"
Reactome:REACT_28565 "eNOS activation, Staphylococcus aureus N315"
Reactome:REACT_32691 "eNOS activation, Dictyostelium discoideum"
Reactome:REACT_82873 "eNOS activation, Escherichia coli"
Reactome:REACT_84429 "eNOS activation, Drosophila melanogaster"
Reactome:REACT_87573 "eNOS activation and regulation, Staphylococcus aureus N315"
Reactome:REACT_88732 "eNOS activation and regulation, Drosophila melanogaster"
Reactome:REACT_89487 "eNOS activation and regulation, Dictyostelium discoideum"
xref
Reactome:REACT_112087 "eNOS activation and regulation, Taeniopygia guttata"
Reactome:REACT_114898 "eNOS activation, Taeniopygia guttata"
GO:0051084 : 'de novo' posttranslational protein folding
xref
Reactome:REACT_30483 "Protein folding, Plasmodium falciparum"
xref
Reactome:REACT_90293 "Protein folding, Plasmodium falciparum"
GO:0051092 : positive regulation of NF-kappaB transcription factor activity
xref
Reactome:REACT_113398 "TAK1 activates NFkB by phosphorylation and activation of IKKs complex, Taeniopygia guttata"
Reactome:REACT_113766 "TAK1 activates NFkB by phosphorylation and activation of IKKs complex, Drosophila melanogaster"
GO:0051118 : glucan endo-1,3-alpha-glucosidase activity
def
Catalysis of the endohydrolysis of 1,3-alpha-D-glucosidic linkages in isolichenin, pseudonigeran and nigeran.
def
Catalysis of the endohydrolysis of (1->3)-alpha-D-glucosidic linkages in isolichenin, pseudonigeran and nigeran.
GO:0051119 : sugar transmembrane transporter activity
xref
Reactome:REACT_81012 "GLUT7 and GLUT11 transport glucose and fructose, Drosophila melanogaster"
xref
Reactome:REACT_112187 "GLUT7 and GLUT11 transport glucose and fructose, Plasmodium falciparum"
Reactome:REACT_113009 "GLUT7 and GLUT11 transport glucose and fructose, Dictyostelium discoideum"
Reactome:REACT_113132 "GLUT7 and GLUT11 transport glucose and fructose, Oryza sativa"
Reactome:REACT_113932 "GLUT7 and GLUT11 transport glucose and fructose, Mycobacterium tuberculosis"
Reactome:REACT_113992 "GLUT7 and GLUT11 transport glucose and fructose, Arabidopsis thaliana"
GO:0051139 : metal ion:hydrogen antiporter activity
xref
Reactome:REACT_112591 "NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages, Staphylococcus aureus N315"
GO:0051149 : positive regulation of muscle cell differentiation
xref
Reactome:REACT_113620 "CDO in myogenesis, Caenorhabditis elegans"
GO:0051168 : nuclear export
xref
Reactome:REACT_112801 "Nuclear export of snRNA transcripts, Drosophila melanogaster"
Reactome:REACT_113944 "Nuclear export of snRNA transcripts, Danio rerio"
GO:0051170 : nuclear import
xref
Reactome:REACT_86962 "snRNP nuclear import and release, Bos taurus"
GO:0051394 : regulation of nerve growth factor receptor activity
is_a
GO:0043393
GO:0051395 : negative regulation of nerve growth factor receptor activity
is_a
GO:0032091
GO:0051396 : positive regulation of nerve growth factor receptor activity
is_a
GO:0032092
GO:0051421 : regulation of endo-1,4-beta-xylanase activity
def
Any process that modulates the frequency, rate or extent of endo-1,4-beta-xylanase activity, the catalysis of the endohydrolysis of 1,4-beta-D-xylosidic linkages in xylans.
def
Any process that modulates the frequency, rate or extent of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
GO:0051422 : negative regulation of endo-1,4-beta-xylanase activity
def
Any process that stops or reduces the rate of endo-1,4-beta-xylanase activity, the catalysis of the endohydrolysis of 1,4-beta-D-xylosidic linkages in xylans.
def
Any process that stops or reduces the rate of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
GO:0051423 : positive regulation of endo-1,4-beta-xylanase activity
def
Any process that activates or increases the frequency, rate or extent of endo-1,4-beta-xylanase activity, the catalysis of the endohydrolysis of 1,4-beta-D-xylosidic linkages in xylans.
def
Any process that activates or increases the frequency, rate or extent of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
GO:0051436 : negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
xref
Reactome:REACT_106068 "Autodegradation of Cdh1 by Cdh1:APC/C, Arabidopsis thaliana"
Reactome:REACT_79515 "Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components, Caenorhabditis elegans"
Reactome:REACT_79948 "Phosphorylation of Cdh1 by Cyclin B1:Cdc2, Caenorhabditis elegans"
Reactome:REACT_87706 "Association of Emi1 with Cdh1, Sus scrofa"
xref
Reactome:REACT_101227 "Association of Emi1 with Cdh1, Sus scrofa"
Reactome:REACT_113042 "Phosphorylation of Cdh1 by Cyclin B1:Cdc2, Saccharomyces cerevisiae"
Reactome:REACT_113195 "Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components, Arabidopsis thaliana"
Reactome:REACT_113808 "Phosphorylation of Cdh1 by Cyclin B1:Cdc2, Schizosaccharomyces pombe"
Reactome:REACT_114563 "Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components, Oryza sativa"
GO:0051437 : positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
xref
Reactome:REACT_101549 "SCF-beta-TrCP mediated degradation of Emi1, Schizosaccharomyces pombe"
Reactome:REACT_87110 "Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1, Drosophila melanogaster"
Reactome:REACT_93035 "SCF-beta-TrCP mediated degradation of Emi1, Caenorhabditis elegans"
xref
Reactome:REACT_112598 "Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1, Bos taurus"
Reactome:REACT_113510 "Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1, Arabidopsis thaliana"
GO:0051439 : regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
xref
Reactome:REACT_103190 "Regulation of APC/C activators between G1/S and early anaphase, Caenorhabditis elegans"
xref
Reactome:REACT_114183 "Regulation of APC/C activators between G1/S and early anaphase, Saccharomyces cerevisiae"
GO:0051726 : regulation of cell cycle
xref
Reactome:REACT_81253 "Inactivation of Myt1 kinase, Saccharomyces cerevisiae"
Reactome:REACT_85274 "Activation of Cdc25C, Danio rerio"
Reactome:REACT_96416 "Activation of Cdc25C, Dictyostelium discoideum"
xref
Reactome:REACT_112480 "Inactivation of Wee1 kinase, Dictyostelium discoideum"
Reactome:REACT_113569 "Activation of Cdc25C, Saccharomyces cerevisiae"
Reactome:REACT_113990 "Activation of Cdc25C, Schizosaccharomyces pombe"
Reactome:REACT_114323 "Activation of Cdc25C, Caenorhabditis elegans"
Reactome:REACT_83089 "Inactivation of Myt1 kinase, Saccharomyces cerevisiae"
GO:0051751 : alpha-1,4-mannosyltransferase activity
def
Catalysis of the transfer of a mannose residue from GDP-mannose to an oligosaccharide, forming an alpha-1,4-linkage.
def
Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->4) linkage.
GO:0051753 : mannan synthase activity
def
Catalysis of the reaction: mannan(n) + GDP-mannose = mannan(n+1) + GDP. This reaction is the formation of the beta-1,4-linked mannan backbone in substrates such as galactomannan.
def
Catalysis of the reaction: mannan(n) + GDP-mannose = mannan(n+1) + GDP. This reaction is the formation of the beta-(1->4)-linked mannan backbone in substrates such as galactomannan.
GO:0051765 : inositol tetrakisphosphate kinase activity
is_a
GO:0004428
is_a
GO:0016301
GO:0051766 : inositol trisphosphate kinase activity
is_a
GO:0004428
is_a
GO:0016301
GO:0051818 : disruption of cells of other organism involved in symbiotic interaction
is_a
GO:0044364
GO:0051899 : membrane depolarization
xref
Reactome:REACT_81474 "Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels, Gallus gallus"
xref
Reactome:REACT_114683 "Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels, Xenopus tropicalis"
GO:0052204 : negative regulation of molecular function in other organism involved in symbiotic interaction
is_a
GO:0044362
GO:0052205 : modulation of molecular function in other organism involved in symbiotic interaction
is_a
GO:0044359
GO:0052725 : inositol-1,3,4-trisphosphate 6-kinase activity
xref
Reactome:REACT_25214 "ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5/6-P4, Homo sapiens"
GO:0052726 : inositol-1,3,4-trisphosphate 5-kinase activity
xref
Reactome:REACT_25214 "ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5/6-P4, Homo sapiens"
GO:0052742 : phosphatidylinositol kinase activity
is_a
GO:0004428
is_a
GO:0016301
GO:0052744 : phosphatidylinositol monophosphate phosphatase activity
is_a
GO:0004437
is_a
GO:0016791
GO:0052745 : inositol phosphate phosphatase activity
is_a
GO:0004437
is_a
GO:0016791
GO:0052756 : chitobiose phosphorylase activity
def
Catalysis of the reaction: chitobiose + phosphate = N-acetyl-D-glucosamine + N-acetyl-alpha-D-glucosamine 1-phosphate. This reaction is the phosphorolysis of chitobiose, (GlcNAc)2, a dimer of beta-1,4-linked glucosamine units.
def
Catalysis of the reaction: chitobiose + phosphate = N-acetyl-D-glucosamine + N-acetyl-alpha-D-glucosamine 1-phosphate. This reaction is the phosphorolysis of chitobiose, (GlcNAc)2, a dimer of beta-(1->4) linked glucosamine units.
GO:0052761 : exo-1,4-beta-D-glucosaminidase activity
def
Catalysis of the reaction: [beta-(1,4)-D-glucosamine]n-[N-acetyl-D-glucosamine]m = D-glucosamine + [beta-(1,4)-D-glucosamine](n-1)-[N-acetyl-D-glucosamine]m. This reaction is the hydrolysis of chitosan or chitosan oligosaccharides to remove a D-glucosamine residue from the non-reducing termini; chitosan is a linear polysaccharide composed of randomly distributed beta-(1,4)-linked D-glucosamine and N-acetyl-D-glucosamine units.
def
Catalysis of the reaction: [beta-(1->4)-D-glucosamine]n-[N-acetyl-D-glucosamine]m = D-glucosamine + [beta-(1->4)-D-glucosamine](n-1)-[N-acetyl-D-glucosamine]m. This reaction is the hydrolysis of chitosan or chitosan oligosaccharides to remove a D-glucosamine residue from the non-reducing termini; chitosan is a linear polysaccharide composed of randomly distributed beta-(1->4)-linked D-glucosamine and N-acetyl-D-glucosamine units.
GO:0052762 : gellan lyase activity
def
Catalysis of the reaction: gellan = n beta-D-4-deoxy-delta4,5-GlcAp-(1,4)-beta-D-Glcp-(1,4)-alpha-L-Rhap-(1,3)-beta-D-Glcp. This reaction is the eliminative cleavage of beta-D-glucopyranosyl-(1,4)-beta-D-glucopyranosyluronate bonds of gellan backbone, releasing tetrasaccharides containing a 4-deoxy-4,5-unsaturated D-glucopyranosyluronic acid at the non-reducing end; in the product, the abbreviations are D-glucose (Glc), D-glucuronic acid (GlcA), and L-rhamnose (Rha).
def
Catalysis of the reaction: gellan = n beta-D-4-deoxy-delta4,5-GlcAp-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp. This reaction is the eliminative cleavage of beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyluronate bonds of gellan backbone, releasing tetrasaccharides containing a 4-deoxy-4,5-unsaturated D-glucopyranosyluronic acid at the non-reducing end; in the product, the abbreviations are D-glucose (Glc), D-glucuronic acid (GlcA), and L-rhamnose (Rha).
GO:0052763 : ulvan lyase activity
def
Catalysis of the cleavage of a carbon-oxygen bond in ulvan, a carbohydrate composed of a repeating structure of [->4)-beta-D-GlcA-(1,4)-alpha-L-Rha 3S-(1,4)-alpha-L-IdoA-(1,4)-alpha-L-Rha 3S-(1->]n. Continued digest of ulvan with an enzyme that can catalyze this reaction results in ulvanobiouronic acid A 3-sulfate [->4)-beta-D-GlcpA-(1,4)-alpha-L-Rhap 3-sulfate-(1->]n with 4-deoxy-L-threo-hex-4-enopyranosiduronic acid at the non-reducing end.
def
Catalysis of the cleavage of a carbon-oxygen bond in ulvan, a carbohydrate composed of a repeating structure of [->4)-beta-D-GlcA-(1,4)-alpha-L-Rha 3S-(1->4)-alpha-L-IdoA-(1->4)-alpha-L-Rha 3S-(1-]n. Continued digest of ulvan with an enzyme that can catalyze this reaction results in ulvanobiouronic acid A 3-sulfate [->4)-beta-D-GlcpA-(1->4)-alpha-L-Rhap 3-sulfate-(1-]n with 4-deoxy-L-threo-hex-4-enopyranosiduronic acid at the non-reducing end.
GO:0052764 : exo-oligoalginate lyase activity
def
Catalysis of the cleavage of glycosidic bonds through a beta-elimination reaction on alginate, a linear polysaccharide consisting of guluronate (G) and mannuronate (M) as the monomer constituents. An oligoalginate is a linear polymer of two, three or four units of (1,4) alpha-L-guluronic acid and beta-D-mannuronic acid, releasing monosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends.
def
Catalysis of the cleavage of glycosidic bonds through a beta-elimination reaction on alginate, a linear polysaccharide consisting of guluronate (G) and mannuronate (M) as the monomer constituents. An oligoalginate is a linear polymer of two, three or four units of (1->4)-alpha-L-guluronic acid and beta-D-mannuronic acid, releasing monosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends.
GO:0052766 : mannoside alpha-1,4-mannosidase activity
def
Catalysis of the hydrolysis of the alpha-1,4 linkage of the terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.
def
Catalysis of the hydrolysis of the alpha-(1->4) linkage of the terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.
GO:0052767 : mannosyl-oligosaccharide 1,6-alpha-mannosidase activity
def
Catalysis of the hydrolysis of the alpha-1,6 bonds of alpha-D-mannose residues in mannosyl-oligosaccharide.
def
Catalysis of the hydrolysis of the alpha-(1->6) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide.
synonym
"alpha-1,6-mannosyl-oligosaccharide alpha-D-mannohydrolase activity" EXACT []
GO:0052768 : mannosyl-oligosaccharide 1,3-alpha-mannosidase activity
def
Catalysis of the hydrolysis of the alpha-1,3 bonds of alpha-D-mannose residues in mannosyl-oligosaccharide.
synonym
"1,4-alpha-mannosidase activity" BROAD []
"1,4-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity" EXACT []
"alpha-1,4-mannosidase activity" BROAD []
def
Catalysis of the hydrolysis of the alpha-(1->3) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide.
synonym
"1,3-alpha-mannosidase activity" BROAD []
"1,3-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity" EXACT []
"alpha-1,3-mannosidase activity" BROAD []
"alpha-1,3-mannosyl-oligosaccharide alpha-D-mannohydrolase activity" EXACT []
GO:0052769 : beta-6-sulfate-N-acetylglucosaminidase activity
synonym
"beta-6-SO3-N-acetylglucosaminidase activity" BROAD []
GO:0052775 : endo-1,3-alpha-L-rhamnosidase activity
def
Catalysis of the reaction: R1-L-rhamnose-(1,3)-alpha-L-rhamnose-R2 + H2O = R1-L-rhamnose + L-rhamnose-R2. This reaction is the hydrolysis of an alpha-1,3-linkage between two rhamnose residues in a polysaccharide chain.
def
Catalysis of the reaction: R1-L-rhamnose-(1->3)-alpha-L-rhamnose-R2 + H2O = R1-L-rhamnose + L-rhamnose-R2. This reaction is the hydrolysis of an alpha-(1->3) linkage between two rhamnose residues in a polysaccharide chain.
synonym
"endo-(1,3)-alpha-L-rhamnosidase activity" EXACT []
"endo-(1->3)-alpha-L-rhamnosidase activity" EXACT []
GO:0052786 : alpha-linked polysaccharide catabolism to maltotriose
def
The breakdown of large alpha-linked polysaccharides by hydrolysis of 1,4-alpha-D-glucosidic linkages to yield maltotriose.
def
The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltotriose.
GO:0052787 : alpha-linked polysaccharide catabolism to maltopentaose
def
The breakdown of large alpha-linked polysaccharides by hydrolysis of 1,4-alpha-D-glucosidic linkages to yield maltopentaose.
def
The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltopentaose.
GO:0052789 : mannan 1,3-beta-mannosidase activity
def
Catalysis of the hydrolysis of 1,3-beta-D-mannosidic linkages in mannans, releasing mannose.
def
Catalysis of the hydrolysis of (1->3)-beta-D-mannosidic linkages in mannans, releasing mannose.
GO:0052790 : chitooligosaccharide deacetylase activity
def
Catalysis of the reaction: chitooligosaccharide with N-acetylglucosamine at nonreducing terminal + H2O = chitooligosaccharide with glucosamine at nonreducing terminal + acetate. This reaction is the deacetylation of a chitooligosaccharide at the nonreducing N-acetylglucosamine residue; chitooligosaccharide are composed of -1,4-linked-D-glucosamine (GlcN) and N-acetyl-D-glucosamine (GlcNAc) in varying proportions.
def
Catalysis of the reaction: chitooligosaccharide with N-acetylglucosamine at nonreducing terminal + H2O = chitooligosaccharide with glucosamine at nonreducing terminal + acetate. This reaction is the deacetylation of a chitooligosaccharide at the nonreducing N-acetylglucosamine residue; chitooligosaccharide are composed of (1->4)-linked D-glucosamine (GlcN) and N-acetyl-D-glucosamine (GlcNAc) in varying proportions.
GO:0052794 : exo-alpha-(2->3)-sialidase activity
name
exo-alpha-(2,3)-sialidase activity
name
exo-alpha-(2->3)-sialidase activity
synonym
"exo-alpha-(2,3)-sialidase activity" EXACT []
"exo-alpha-2,3-sialidase activity" EXACT []
GO:0052795 : exo-alpha-(2->6)-sialidase activity
name
exo-alpha-(2,6)-sialidase activity
name
exo-alpha-(2->6)-sialidase activity
synonym
"exo-alpha-(2,6)-sialidase activity" EXACT []
"exo-alpha-2,6-sialidase activity" EXACT []
GO:0052796 : exo-alpha-(2->8)-sialidase activity
name
exo-alpha-(2,8)-sialidase activity
name
exo-alpha-(2->8)-sialidase activity
synonym
"exo-alpha-(2,8)-sialidase activity" EXACT []
"exo-alpha-2,8-sialidase activity" EXACT []
GO:0055056 : D-glucose transmembrane transporter activity
xref
Reactome:REACT_109737 "Glucose transport by class III GLUTs, Mycobacterium tuberculosis"
Reactome:REACT_34322 "Glucose transport by class III GLUTs, Dictyostelium discoideum"
Reactome:REACT_79045 "Glucose transport by class III GLUTs, Sus scrofa"
Reactome:REACT_83648 "Glucose transport by class III GLUTs, Drosophila melanogaster"
Reactome:REACT_87643 "Glucose transport by class III GLUTs, Escherichia coli"
xref
Reactome:REACT_113478 "Glucose transport by class I GLUTs, Caenorhabditis elegans"
Reactome:REACT_113923 "Glucose transport by class I GLUTs, Plasmodium falciparum"
Reactome:REACT_114069 "Glucose transport by class I GLUTs, Dictyostelium discoideum"
Reactome:REACT_114121 "Glucose transport by class I GLUTs, Mycobacterium tuberculosis"
Reactome:REACT_114352 "Glucose transport by class I GLUTs, Drosophila melanogaster"
Reactome:REACT_114492 "Glucose transport by class I GLUTs, Arabidopsis thaliana"
Reactome:REACT_115387 "Glucose transport by class I GLUTs, Oryza sativa"
Reactome:REACT_81510 "Glucose transport by class III GLUTs, Sus scrofa"
GO:0055085 : transmembrane transport
xref
Reactome:REACT_28801 "Transmembrane transport of small molecules, Sus scrofa"
Reactome:REACT_32562 "SLC-mediated transmembrane transport, Sus scrofa"
xref
Reactome:REACT_101975 "SLC-mediated transmembrane transport, Sus scrofa"
Reactome:REACT_114546 "ABC-family proteins mediated transport, Staphylococcus aureus N315"
Reactome:REACT_114763 "ABC-family proteins mediated transport, Escherichia coli"
Reactome:REACT_114890 "ABC-family proteins mediated transport, Plasmodium falciparum"
Reactome:REACT_115378 "ABC-family proteins mediated transport, Mycobacterium tuberculosis"
Reactome:REACT_96633 "Transmembrane transport of small molecules, Sus scrofa"
GO:0055086 : nucleobase-containing small molecule metabolic process
xref
Reactome:REACT_90371 "Metabolism of nucleotides, Sus scrofa"
xref
Reactome:REACT_31512 "Metabolism of nucleotides, Sus scrofa"
GO:0060397 : JAK-STAT cascade involved in growth hormone signaling pathway
xref
Reactome:REACT_111133 "Growth hormone receptor signaling, Homo sapiens"
GO:0060624 : regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process
name
regulation of ascospore wall 1,3-beta-D-glucan biosynthetic process
def
Any process that modulates the rate, frequency, or extent of ascospore wall 1,3-beta-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of 1,3-beta-glucans, compounds composed of glucose residues linked by 1,3-beta-D-glucosidic bonds, found in the walls of ascospores.
name
regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process
def
Any process that modulates the rate, frequency, or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D--glucosidic bonds, found in the walls of ascospores.
synonym
"regulation of ascospore wall 1,3-beta-D-glucan biosynthetic process" BROAD []
GO:0060634 : regulation of 4,6-pyruvylated galactose residue biosynthetic process
def
Any process that modulates the rate, frequency, or extent of 4,6-pyruvylated galactose residue biosynthetic process, the chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain.
def
Any process that modulates the rate, frequency, or extent of 4,6-pyruvylated galactose residue biosynthetic process, the chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-(1->3)-. The galactose residue is part of a larger polysaccharide chain.
GO:0060635 : positive regulation of (1->3)-beta-D-glucan biosynthetic process
name
positive regulation of 1,3-beta-D-glucan biosynthetic process
def
Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta-1,3 glucans.
synonym
"positive regulation of 1,3-beta-glucan biosynthetic process" BROAD []
name
positive regulation of (1->3)-beta-D-glucan biosynthetic process
def
Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.
synonym
"positive regulation of 1,3-beta-D-glucan biosynthetic process" EXACT []
GO:0060636 : negative regulation of (1->3)-beta-D-glucan biosynthetic process
name
negative regulation of 1,3-beta-D-glucan biosynthetic process
def
Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta-1,3 glucans.
synonym
"negative regulation of 1,3-beta-glucan biosynthetic process" BROAD []
name
negative regulation of (1->3)-beta-D-glucan biosynthetic process
def
Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.
synonym
"negative regulation of 1,3-beta-D-glucan biosynthetic process" EXACT []
GO:0060917 : regulation of (1->6)-beta-D-glucan biosynthetic process
name
regulation of 1,6-beta-glucan biosynthetic process
def
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta-1,6 glucans.
name
regulation of (1->6)-beta-D-glucan biosynthetic process
def
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans.
synonym
"regulation of 1,6-beta-glucan biosynthetic process" EXACT []
GO:0070251 : pristanate-CoA ligase activity
xref
Reactome:REACT_112851 "pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate, Taeniopygia guttata"
Reactome:REACT_113004 "pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate, Saccharomyces cerevisiae"
GO:0070371 : ERK1 and ERK2 cascade
xref
Reactome:REACT_112775 "ERK2 activation, Arabidopsis thaliana"
Reactome:REACT_112819 "ERK2 activation, Dictyostelium discoideum"
Reactome:REACT_115367 "ERK2 activation, Oryza sativa"
GO:0070380 : high mobility group box 1 receptor activity
is_a
GO:0070379
relationship
has_part GO:0070379
GO:0070423 : nucleotide-binding oligomerization domain containing signaling pathway
xref
Reactome:REACT_112657 "NOD1/2 Signaling Pathway, Drosophila melanogaster"
GO:0070506 : high-density lipoprotein particle receptor activity
is_a
GO:0008035
relationship
has_part GO:0008035
GO:0070595 : (1->3)-alpha-glucan metabolic process
name
1,3-alpha-glucan metabolic process
def
The chemical reactions and pathways involving alpha-1,3 glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds.
name
(1->3)-alpha-glucan metabolic process
def
The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.
synonym
"1,3-alpha-glucan metabolic process" EXACT [GOC:mah]
GO:0070596 : (1->3)-alpha-glucan biosynthetic process
name
1,3-alpha-glucan biosynthetic process
def
The chemical reactions and pathways resulting in the formation of alpha-1,3 glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds.
name
(1->3)-alpha-glucan biosynthetic process
def
The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.
synonym
"1,3-alpha-glucan biosynthetic process" EXACT [GOC:mah]
GO:0070597 : cell wall (1->3)-alpha-glucan metabolic process
name
cell wall 1,3-alpha-glucan metabolic process
def
The chemical reactions and pathways involving alpha-1,3 glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds, found in the walls of cells.
name
cell wall (1->3)-alpha-glucan metabolic process
def
The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.
synonym
"cell wall 1,3-alpha-glucan metabolic process" EXACT [GOC:mah]
GO:0070598 : cell wall (1->3)-alpha-glucan biosynthetic process
name
cell wall 1,3-alpha-glucan biosynthetic process
def
The chemical reactions and pathways resulting in the formation of 1,3-alpha-glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds, found in the walls of cells.
name
cell wall (1->3)-alpha-glucan biosynthetic process
def
The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-glucosidic bonds, found in the walls of cells.
synonym
"cell wall 1,3-alpha-glucan biosynthetic process" EXACT [GOC:mah]
GO:0070599 : fungal-type cell wall (1->3)-alpha-glucan metabolic process
name
fungal-type cell wall 1,3-alpha-glucan metabolic process
def
The chemical reactions and pathways involving alpha-1,3 glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds, found in the walls of ascospores.
name
fungal-type cell wall (1->3)-alpha-glucan metabolic process
def
The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores.
synonym
"ascospore wall 1,3-alpha-glucan metabolic process" EXACT [GOC:mah]
GO:0070600 : fungal-type cell wall (1->3)-alpha-glucan biosynthetic process
name
fungal-type cell wall 1,3-alpha-glucan biosynthetic process
def
The chemical reactions and pathways resulting in the formation of 1,3-alpha-glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.
name
fungal-type cell wall (1->3)-alpha-glucan biosynthetic process
def
The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.
synonym
"fungal-type cell wall 1,3-alpha-glucan biosynthetic process" EXACT [GOC:mah]
GO:0070605 : regulation of (1->3)-alpha-glucan metabolic process
name
regulation of 1,3-alpha-glucan metabolic process
def
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving alpha-1,3 glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds.
name
regulation of (1->3)-alpha-glucan metabolic process
def
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.
synonym
"regulation of 1,3-alpha-glucan metabolic process" EXACT [GOC:mah]
GO:0070606 : regulation of (1->3)-alpha-glucan biosynthetic process
name
regulation of 1,3-alpha-glucan biosynthetic process
def
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of alpha-1,3 glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds.
name
regulation of (1->3)-alpha-glucan biosynthetic process
def
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.
synonym
"regulation of 1,3-alpha-glucan biosynthetic process" EXACT [GOC:mah]
GO:0070607 : regulation of cell wall (1->3)-alpha-glucan metabolic process
name
regulation of cell wall 1,3-alpha-glucan metabolic process
def
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving alpha-1,3 glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds, found in the walls of cells.
name
regulation of cell wall (1->3)-alpha-glucan metabolic process
def
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.
synonym
"regulation of cell wall 1,3-alpha-glucan metabolic process" EXACT [GOC:mah]
GO:0070608 : regulation of cell wall (1->3)-alpha-glucan biosynthetic process
name
regulation of cell wall 1,3-alpha-glucan biosynthetic process
def
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of 1,3-alpha-glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds, found in the walls of cells.
name
regulation of cell wall (1->3)-alpha-glucan biosynthetic process
def
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.
synonym
"regulation of cell wall 1,3-alpha-glucan biosynthetic process" EXACT [GOC:mah]
GO:0070609 : regulation of fungal-type cell wall (1->3)-alpha-glucan metabolic process
name
regulation of fungal-type cell wall 1,3-alpha-glucan metabolic process
def
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving alpha-1,3 glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds, found in the walls of ascospores.
name
regulation of fungal-type cell wall (1->3)-alpha-glucan metabolic process
def
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores.
synonym
"regulation of fungal-type cell wall 1,3-alpha-glucan metabolic process" EXACT [GOC:mah]
GO:0070610 : regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process
name
regulation of fungal-type cell wall 1,3-alpha-glucan biosynthetic process
def
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of 1,3-alpha-glucans, compounds composed of glucose residues linked by 1,3-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.
synonym
"regulation of fungal type cell wall 1,3-alpha-glucan biosynthetic process" RELATED [GOC:dph, GOC:tb]
name
regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process
def
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.
synonym
"regulation of fungal type cell wall 1,3-alpha-glucan biosynthetic process" EXACT [GOC:dph, GOC:tb]
GO:0070629 : (1->4)-alpha-glucan metabolic process
name
1,4-alpha-glucan metabolic process
def
The chemical reactions and pathways involving alpha-1,4 glucans, compounds composed of glucose residues linked by 1,4-alpha-D-glucosidic bonds.
name
(1->4)-alpha-glucan metabolic process
def
The chemical reactions and pathways involving (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds.
synonym
"(1->4)-alpha-D-glucan metabolism" EXACT [GOC:mah]
"1,4-alpha-D-glucan metabolism" EXACT [GOC:mah]
GO:0070630 : (1->4)-alpha-glucan biosynthetic process
name
1,4-alpha-glucan biosynthetic process
def
The chemical reactions and pathways resulting in the formation of alpha-1,4 glucans, compounds composed of glucose residues linked by 1,4-alpha-D-glucosidic bonds.
name
(1->4)-alpha-glucan biosynthetic process
def
The chemical reactions and pathways resulting in the formation of (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds.
synonym
"(1->4)-alpha-D-glucan anabolism" EXACT [GOC:mah]
"(1->4)-alpha-D-glucan biosynthesis" EXACT [GOC:mah]
"(1->4)-alpha-D-glucan formation" EXACT [GOC:mah]
"(1->4)-alpha-D-glucan synthesis" EXACT [GOC:mah]
"1,4-alpha-glucan biosynthetic process" EXACT [GOC:mah]
GO:0070747 : interleukin-35 receptor activity
is_a
GO:0070746
relationship
has_part GO:0070746
GO:0070780 : dihydrosphingosine-1-phosphate phosphatase activity
xref
Reactome:REACT_113400 "sphinganine 1-phosphate + H2O => sphinganine + orthophosphate, Schizosaccharomyces pombe"
Reactome:REACT_114387 "sphinganine 1-phosphate + H2O => sphinganine + orthophosphate, Saccharomyces cerevisiae"
GO:0070892 : lipoteichoic acid receptor activity
is_a
GO:0070891
relationship
has_part GO:0070891
GO:0070915 : lysophosphatidic acid receptor activity
def
Combining with lysophosphatidic acid to initiate a change in cell activity.
def
Combining with the phospholipid derivative lysophosphatidic acid, and transmitting the signal across the membrane by activating an associated G-protein.
synonym
"LPA receptor activity" EXACT [PMID:15755723]
relationship
has_part GO:0035727
GO:0071344 : diphosphate metabolic process
xref
Reactome:REACT_107476 "Pyrophosphate hydrolysis, Schizosaccharomyces pombe"
Reactome:REACT_28188 "Pyrophosphate hydrolysis, Sus scrofa"
Reactome:REACT_99059 "Pyrophosphate hydrolysis, Caenorhabditis elegans"
xref
Reactome:REACT_100411 "Pyrophosphate hydrolysis, Sus scrofa"
Reactome:REACT_112316 "Pyrophosphate hydrolysis, Oryza sativa"
Reactome:REACT_113577 "Pyrophosphate hydrolysis, Plasmodium falciparum"
Reactome:REACT_114742 "Pyrophosphate hydrolysis, Arabidopsis thaliana"
Reactome:REACT_115179 "Pyrophosphate hydrolysis, Mycobacterium tuberculosis"
Reactome:REACT_34239 "Pyrophosphate hydrolysis, Schizosaccharomyces pombe"
Reactome:REACT_81374 "Pyrophosphate hydrolysis, Caenorhabditis elegans"
GO:0071377 : cellular response to glucagon stimulus
xref
Reactome:REACT_113140 "Glucagon signaling in metabolic regulation, Plasmodium falciparum"
GO:0071553 : G-protein coupled pyrimidinergic nucleotide receptor activity
relationship
has_part GO:0019103
GO:0071634 : regulation of transforming growth factor beta production
synonym
"regulation of TGFb production" EXACT [GOC:mah]
GO:0071635 : negative regulation of transforming growth factor beta production
synonym
"negative regulation of TGFb production" EXACT [GOC:mah]
GO:0071636 : positive regulation of transforming growth factor beta production
synonym
"positive regulation of TGFb production" EXACT [GOC:mah]
GO:0071898 : regulation of estrogen receptor binding
is_a
GO:0043393
GO:0071969 : fungal-type cell wall (1->3)-beta-D-glucan metabolic process
name
fungal-type cell wall 1,3-beta-D-glucan metabolic process
def
The chemical reactions and pathways involving 1,3-beta-glucans, compounds composed of glucose residues linked by 1,3-beta-D-glucosidic bonds, found in the walls of ascospores.
synonym
"fungal-type cell wall 1,3-beta-glucan metabolic process" BROAD []
name
fungal-type cell wall (1->3)-beta-D-glucan metabolic process
def
The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.
synonym
"fungal-type cell wall 1,3-beta-D-glucan metabolic process" EXACT []
GO:0071970 : fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process
name
fungal-type cell wall 1,3-beta-D-glucan biosynthetic process
def
The chemical reactions and pathways resulting in the formation of 1,3-beta-glucans, compounds composed of glucose residues linked by 1,3-beta-D-glucosidic bonds, found in the walls of ascospores.
synonym
"fungal-type cell wall 1,3-beta-glucan biosynthetic process" BROAD []
name
fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process
def
The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.
synonym
"fungal-type cell wall 1,3-beta-D-glucan biosynthetic process" EXACT []
GO:0072078 : nephron tubule morphogenesis
relationship
part_of GO:0072028
GO:0072088 : nephron epithelium morphogenesis
relationship
part_of GO:0072028
GO:0090282 : positive regulation of transcription involved in G2/M-phase of mitotic cell cycle
intersection_of
GO:0045893
part_of GO:0000086
GO:0090334 : regulation of cell wall (1->3)-beta-D-glucan biosynthetic process
name
regulation of cell wall 1,3-beta-D-glucan biosynthetic process
def
Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of 1,3-beta-glucans, compounds composed of glucose residues linked by 1,3-beta-D-glucosidic bonds, found in the walls of cells.
name
regulation of cell wall (1->3)-beta-D-glucan biosynthetic process
def
Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.
synonym
"regulation of cell wall 1,3-beta-D-glucan biosynthetic process" BROAD []
GO:0097003 : adipokinetic hormone receptor activity
relationship
has_part GO:0055100
has_part GO:0097004
GO:2001077 : (1->3),(1->4)-beta-glucan binding
name
beta-1,3-1,4-glucan binding
def
Interacting selectively and non-covalently with beta-1,3-1,4-glucan.
name
(1->3),(1->4)-beta-glucan binding
def
Interacting selectively and non-covalently with (1->3),(1->4)-beta-glucan.
synonym
"(1,3),(1,4)-beta-glucan binding" EXACT []
"1->3,1->4-beta-glucan binding" EXACT []
"beta-(1,3),(1,4)-glucan binding" EXACT []
"beta-(1->3),(1->4)-glucan binding" EXACT []
"beta-1,3-1,4-glucan binding" EXACT []
"beta-1->3,1->4-glucan binding" EXACT []
GO:2001078 : (1->6)-beta-D-glucan binding
name
beta-1,6-D-glucan binding
def
Interacting selectively and non-covalently with beta-1,6-D-glucan.
name
(1->6)-beta-D-glucan binding
def
Interacting selectively and non-covalently with (1->6)-beta-D-glucan.
synonym
"(1,6)-beta-D-glucan binding" EXACT []
"1,6-beta-D-glucan binding" EXACT []
"1->6-beta-D-glucan binding" EXACT []
"beta-(1,6)-D-glucan binding" EXACT []
"beta-(1->6)-D-glucan binding" EXACT []
"beta-1,6-D-glucan binding" EXACT []
"beta-1->6-D-glucan binding" EXACT []
GO:2001081 : (1->4)-beta-D-galactan binding
synonym
"(1,4)-beta-D-galactan binding" EXACT []

File Stats

Term counts for the old and new files
Ontology Old file New file Change
molecular function 9138
9138 (100.0%) defined
9148
9148 (100.0%) defined
+10
cellular component 2918
2918 (100.0%) defined
2918
2918 (100.0%) defined
0
biological process 21506
21506 (100.0%) defined
21549
21549 (100.0%) defined
+43
Obsolete 1592
(4.5% of total)
1597
(4.5% of total)
+5 (+0.3%)
Totals 33562
33562 (100.0%) defined
35154 inc. obsoletes
33615
33615 (100.0%) defined
35212 inc. obsoletes
+58 (+0.2%)

Ontology report info