Gene Ontology OBO file definition changes
Files used:
- file 1 (old): 17:06:2011 13:42, cvs revision 1.2042
- file 2 (new): 24:06:2011 15:09, cvs revision 1.2067
- Database: seqdb, 2011-07-09
Terms with changed definitions
GO:0000989 : transcription factor binding transcription factor activity
OLD: Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.
NEW: Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
GO:0000990 : core RNA polymerase binding transcription factor activity
OLD: Interacting selectively and non-covalently with an RNA polymerase in order to modulate transcription.
NEW: Interacting selectively and non-covalently with an RNA polymerase and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
GO:0000991 : core RNA polymerase II binding transcription factor activity
OLD: Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, in order to modulate transcription by Pol II.
NEW: Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
0 annotations
GO:0000995 : core RNA polymerase III binding transcription factor activity
OLD: Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, in order to modulate transcription by Pol III.
NEW: Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
GO:0000996 : core DNA-dependent RNA polymerase binding promoter specificity activity
(was core RNA polymerase binding promoter specificity activity)
OLD: An activity that binds to RNA polymerase and which while present in a complex with the core RNA polymerase confers sequence specific recognition of promoter DNA sequence motifs.
NEW: Interacting selectively and non-covalently with a DNA-dependent core RNA polymerase to form a holoenzyme complex and also, while present in the holoenzyme, interacting with promoter sequences in order to confer sequence specific recognition of promoter DNA sequence motifs.
0 annotations
GO:0001007 : RNA polymerase III transcription factor binding transcription factor activity
OLD: Interacting selectively and non-covalently with an RNA polymerase III transcription factor in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.
NEW: Interacting selectively and non-covalently with an RNA polymerase III transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
0 annotations
GO:0001026 : TFIIIB-type transcription factor activity
OLD: Once recruited to an RNA polymerase III promoter by one or more other transcription factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.
NEW: Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, Once recruited to an RNA polymerase III promoter by one or more other transcription factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.
0 annotations
GO:0001027 : RNA polymerase III type 1 promoter TFIIIB-type transcription factor activity
OLD: Once recruited to an RNA polymerase III type 1 promoter by TFIIIA-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.
NEW: Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 1 promoter by TFIIIA-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.
0 annotations
GO:0001028 : RNA polymerase III type 2 promoter TFIIIB-type transcription factor activity
OLD: Once recruited to an RNA polymerase III type 2 promoter by a TFIIIC-type factor, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.
NEW: Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 2 promoter by a TFIIIC-type factor, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.
0 annotations
GO:0001029 : RNA polymerase III type 3 promoter TFIIIB-type transcription factor activity
OLD: Once recruited to an RNA polymerase III type 3 promoter by SNAP-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.
NEW: Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 3 promoter by SNAP-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.
0 annotations
GO:0001040 : RNA polymerase III hybrid type promoter TFIIIB-type transcription factor activity
OLD: Once recruited to an RNA polymerase III hybrid type promoter, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.
NEW: Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III hybrid type promoter, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.
0 annotations
GO:0001053 : plastid sigma factor activity
OLD: A sigma factor that binds to the plastid PEP core RNA polymerase enzyme to confer promoter specificity.
NEW: Interacting selectively and non-covalently with a plastid PEP core RNA polymerase to form a holoenzyme complex and also, while present in the holoenzyme, interacting with promoter sequences in order to confer sequence specific recognition of plastid PEP core promoter DNA sequence motifs.
GO:0001076 : RNA polymerase II transcription factor binding transcription factor activity
OLD: Interacting selectively and non-covalently with an RNA polymerase II transcription factor in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.
NEW: Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
0 annotations
GO:0001082 : RNA polymerase I transcription factor binding transcription factor activity
OLD: Interacting selectively and non-covalently with an RNA polymerase I transcription factor in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.
NEW: Interacting selectively and non-covalently with an RNA polymerase I transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
GO:0001083 : RNA polymerase II basal transcription factor binding transcription factor activity
OLD: Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.
NEW: Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
GO:0001134 : transcription factor recruiting transcription factor activity
OLD: The function of binding to a transcription factor and recruiting it to the transcription machinery complex in order to modulate transcription.
NEW: Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, recruiting that specific transcription factor to the transcription machinery complex and thus permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
0 annotations
GO:0001139 : core RNA polymerase II recruiting transcription factor activity
OLD: Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, in order to facilitate the aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.
NEW: Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way in order to facilitate the aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.
GO:0004346 : glucose-6-phosphatase activity
OLD: Catalysis of the reaction: D-glucose 6-phosphate + H2O = D-glucose + phosphate.
NEW: Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate.
GO:0008877 : glucose-1-phosphatase activity
OLD: Catalysis of the reaction: D-glucose 1-phosphate + H2O = D-glucose + phosphate.
NEW: Catalysis of the reaction: alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate.
GO:0019975 : interleukin-17 binding
OLD: Interacting selectively and non-covalently with interleukin-17.
NEW: Interacting selectively and non-covalently with any member of the interleukin-17 family of cytokines.
GO:0030368 : interleukin-17 receptor activity
OLD: Combining with interleukin-17 to initiate a change in cell activity.
NEW: Combining with any member of the interleukin-17 family of cytokines to initiate a change in cell activity.
GO:0031623 : receptor internalization
OLD: A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation; receptors are subsequently taken up into endocytic vesicles and targeted to the lysosome or vacuole for degradation. Receptor internalization serves as a mechanism to downregulate receptor signaling.
NEW: A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane.
GO:0032620 : interleukin-17 production
OLD: The appearance of interleukin-17 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
NEW: The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032660 : regulation of interleukin-17 production
OLD: Any process that modulates the frequency, rate, or extent of interleukin-17 production.
NEW: Any process that modulates the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.
GO:0032700 : negative regulation of interleukin-17 production
OLD: Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-17 production.
NEW: Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.
GO:0032740 : positive regulation of interleukin-17 production
OLD: Any process that activates or increases the frequency, rate, or extent of interleukin-17 production.
NEW: Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.
GO:0033209 : tumor necrosis factor-mediated signaling pathway
OLD: A series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.
NEW: A series of molecular signals generated as a consequence of a tumor necrosis factor binding to a cell surface receptor.
GO:0034246 : mitochondrial RNA polymerase binding promoter specificity activity
OLD: An activity that binds to mitochondrial RNA polymerase and which while present in a complex with the mitochondrial RNA polymerase confers sequence specific recognition of mitochondrial promoter DNA sequence motifs.
NEW: Interacting selectively and non-covalently with a mitochondrial RNA polymerase to form a holoenzyme complex and also, while present in the holoenzyme, interacting with promoter sequences in order to confer sequence specific recognition of mitochondrial promoter DNA sequence motifs.
0 annotations
GO:0042235 : interleukin-17 biosynthetic process
OLD: The chemical reactions and pathways resulting in the formation of interleukin-17.
NEW: The chemical reactions and pathways resulting in the formation of any member of the interleukin-17 family of cytokines.
0 annotations
GO:0045378 : regulation of interleukin-17 biosynthetic process
OLD: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-17.
NEW: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of any member of the interleukin-17 family of cytokines.
0 annotations
GO:0045379 : negative regulation of interleukin-17 biosynthetic process
OLD: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-17.
NEW: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of any member of the interleukin-17 family of cytokines.
0 annotations
GO:0045380 : positive regulation of interleukin-17 biosynthetic process
OLD: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-17.
NEW: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of any member of the interleukin-17 family of cytokines.
GO:0050309 : sugar-terminal-phosphatase activity
OLD: Catalysis of the reaction: H2O + a sugar phosphate = a sugar + phosphate; for example: D-glucose 6-phosphate + H2O = D-glucose + phosphate.
NEW: Catalysis of the reaction: H2O + sugar phosphorylated on the terminal carbon = a sugar + phosphate.
GO:0060414 : aorta smooth muscle tissue morphogenesis
OLD: The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. The aorta originates in the left ventricle of the heart and transports oxygenated blood to the rest of the body.
NEW: The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.
0 annotations
GO:0072615 : interleukin-17 secretion
OLD: The regulated release of interleukin-17 from a cell or group of cells.
NEW: The regulated release of any member of the interleukin-17 family of cytokines from a cell or group of cells.