Ontology Comparison Report ========================== Files used: - file 1 (old): go-2011-06-18.obo; date: 17:06:2011 13:42; CVS revision: 1.2042 - file 2 (new): go-2011-06-25.obo; date: 24:06:2011 15:09; CVS revision: 1.2067 NEW TERMS ========= ID name namespace GO:0001173 DNA-dependent transcriptional start site selection biological_process GO:0001174 transcriptional start site selection at RNA polymerase II promoter biological_process GO:0001175 transcriptional start site selection at RNA polymerase III promoter biological_process GO:0001176 transcriptional start site selection at bacterial-type RNA polymerase promoter biological_process GO:0001177 regulation of transcriptional open complex formation at RNA polymerase II promoter biological_process GO:0001178 regulation of transcriptional start site selection at RNA polymerase II promoter biological_process GO:0002188 translation reinitiation biological_process GO:0035898 parathyroid hormone secretion biological_process GO:0035899 negative regulation of blood coagulation in other organism biological_process GO:0035900 response to isolation stress biological_process GO:0035901 cellular response to isolation stress biological_process GO:0035902 response to immobilization stress biological_process GO:0035903 cellular response to immobilization stress biological_process GO:0035904 aorta development biological_process GO:0035905 ascending aorta development biological_process GO:0035906 descending aorta development biological_process GO:0035907 dorsal aorta development biological_process GO:0035908 ventral aorta development biological_process GO:0035909 aorta morphogenesis biological_process GO:0035910 ascending aorta morphogenesis biological_process GO:0035911 descending aorta morphogenesis biological_process GO:0035912 dorsal aorta morphogenesis biological_process GO:0035913 ventral aorta morphogenesis biological_process GO:0035914 skeletal muscle cell differentiation biological_process GO:0038008 TRAF-mediated signal transduction biological_process GO:0038009 regulation of signal transduction by receptor internalization biological_process GO:0038010 positive regulation of signal transduction by receptor internalization biological_process GO:0038011 negative regulation of signal transduction by receptor internalization biological_process GO:0038012 negative regulation of Wnt receptor signaling pathway by Wnt receptor internalization biological_process GO:0038013 positive regulation of Wnt receptor signaling pathway by Wnt receptor internalization biological_process GO:0038014 negative regulation of insulin receptor signaling pathway by insulin receptor internalization biological_process GO:0038015 positive regulation of insulin receptor signaling pathway by insulin receptor internalization biological_process GO:0038016 insulin receptor internalization biological_process GO:0038017 Wnt receptor internalization biological_process GO:0038018 Wnt receptor catabolic process biological_process GO:0038019 Wnt receptor recycling biological_process GO:0038020 insulin receptor recycling biological_process GO:0039518 suppression by virus of host cytokine activity biological_process GO:0039519 modulation by virus of host autophagy biological_process GO:0039520 induction by virus of host autophagy biological_process GO:0039521 suppression by virus of host autophagy biological_process GO:0039522 suppression by virus of host mRNA export from nucleus biological_process GO:0039523 suppression by virus of host RNA polymerase II activity biological_process GO:0039524 suppression by virus of host mRNA processing biological_process GO:0039525 modulation by virus of host chromatin organization biological_process GO:0039526 modulation by virus of host apoptosis biological_process GO:0039527 suppression by virus of host TRAF-mediated signal transduction biological_process GO:0071963 establishment or maintenance of cell polarity regulating cell shape biological_process GO:0071964 establishment of cell polarity regulating cell shape biological_process GO:0097081 vascular smooth muscle cell fate commitment biological_process GO:0097082 vascular smooth muscle cell fate specification biological_process GO:0097083 vascular smooth muscle cell fate determination biological_process GO:0097084 vascular smooth muscle cell development biological_process GO:0097085 interferon regulatory factor 3-interferon regulatory factor 5 complex cellular_component GO:0097086 amniotic stem cell differentiation biological_process GO:0097087 interleukin-17A production biological_process GO:0097088 interleukin-17F production biological_process GO:2000763 positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process biological_process GO:2000764 positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis biological_process GO:2000765 regulation of cytoplasmic translation biological_process GO:2000766 negative regulation of cytoplasmic translation biological_process GO:2000767 positive regulation of cytoplasmic translation biological_process GO:2000768 positive regulation of nephron tubule epithelial cell differentiation biological_process GO:2000769 regulation of establishment or maintenance of cell polarity regulating cell shape biological_process GO:2000770 negative regulation of establishment or maintenance of cell polarity regulating cell shape biological_process GO:2000771 positive regulation of establishment or maintenance of cell polarity regulating cell shape biological_process GO:2000772 regulation of cellular senescence biological_process GO:2000773 negative regulation of cellular senescence biological_process GO:2000774 positive regulation of cellular senescence biological_process GO:2000775 histone H3-S10 phosphorylation involved in chromosome condensation biological_process GO:2000776 histone H4 acetylation involved in response to DNA damage stimulus biological_process GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia biological_process GO:2000778 positive regulation of interleukin-6 secretion biological_process GO:2000779 regulation of double-strand break repair biological_process GO:2000780 negative regulation of double-strand break repair biological_process GO:2000781 positive regulation of double-strand break repair biological_process GO:2000782 regulation of establishment of cell polarity regulating cell shape biological_process GO:2000783 negative regulation of establishment of cell polarity regulating cell shape biological_process GO:2000784 positive regulation of establishment of cell polarity regulating cell shape biological_process GO:2000785 regulation of autophagic vacuole assembly biological_process GO:2000786 positive regulation of autophagic vacuole assembly biological_process GO:2000787 regulation of venous endothelial cell fate commitment biological_process GO:2000788 negative regulation of venous endothelial cell fate commitment biological_process GO:2000789 positive regulation of venous endothelial cell fate commitment biological_process GO:2000790 regulation of mesenchymal cell proliferation involved in lung development biological_process GO:2000791 negative regulation of mesenchymal cell proliferation involved in lung development biological_process GO:2000792 positive regulation of mesenchymal cell proliferation involved in lung development biological_process GO:2000793 cell proliferation involved in heart valve development biological_process OBSOLETIONS =========== None TERM MERGES =========== None TERM CHANGES ============ GO:0000408 : EKC/KEOPS complex - name: EKC/KEOPS protein complex + name: EKC/KEOPS complex GO:0000988 : protein binding transcription factor activity + subset: high_level_annotation_qc GO:0000989 : transcription factor binding transcription factor activity - def: Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well. + def: Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0000990 : core RNA polymerase binding transcription factor activity - def: Interacting selectively and non-covalently with an RNA polymerase in order to modulate transcription. + def: Interacting selectively and non-covalently with an RNA polymerase and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0000991 : core RNA polymerase II binding transcription factor activity - def: Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, in order to modulate transcription by Pol II. + def: Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0000995 : core RNA polymerase III binding transcription factor activity - def: Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, in order to modulate transcription by Pol III. + def: Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0000996 : core DNA-dependent RNA polymerase binding promoter specificity activity - name: core RNA polymerase binding promoter specificity activity + name: core DNA-dependent RNA polymerase binding promoter specificity activity - def: An activity that binds to RNA polymerase and which while present in a complex with the core RNA polymerase confers sequence specific recognition of promoter DNA sequence motifs. + def: Interacting selectively and non-covalently with a DNA-dependent core RNA polymerase to form a holoenzyme complex and also, while present in the holoenzyme, interacting with promoter sequences in order to confer sequence specific recognition of promoter DNA sequence motifs. GO:0001007 : RNA polymerase III transcription factor binding transcription factor activity - def: Interacting selectively and non-covalently with an RNA polymerase III transcription factor in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well. + def: Interacting selectively and non-covalently with an RNA polymerase III transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0001026 : TFIIIB-type transcription factor activity - def: Once recruited to an RNA polymerase III promoter by one or more other transcription factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex. + def: Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, Once recruited to an RNA polymerase III promoter by one or more other transcription factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex. GO:0001027 : RNA polymerase III type 1 promoter TFIIIB-type transcription factor activity - def: Once recruited to an RNA polymerase III type 1 promoter by TFIIIA-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex. + def: Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 1 promoter by TFIIIA-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex. GO:0001028 : RNA polymerase III type 2 promoter TFIIIB-type transcription factor activity - def: Once recruited to an RNA polymerase III type 2 promoter by a TFIIIC-type factor, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex. + def: Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 2 promoter by a TFIIIC-type factor, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex. GO:0001029 : RNA polymerase III type 3 promoter TFIIIB-type transcription factor activity - def: Once recruited to an RNA polymerase III type 3 promoter by SNAP-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex. + def: Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 3 promoter by SNAP-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex. GO:0001040 : RNA polymerase III hybrid type promoter TFIIIB-type transcription factor activity - def: Once recruited to an RNA polymerase III hybrid type promoter, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex. + def: Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III hybrid type promoter, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex. GO:0001053 : plastid sigma factor activity - def: A sigma factor that binds to the plastid PEP core RNA polymerase enzyme to confer promoter specificity. + def: Interacting selectively and non-covalently with a plastid PEP core RNA polymerase to form a holoenzyme complex and also, while present in the holoenzyme, interacting with promoter sequences in order to confer sequence specific recognition of plastid PEP core promoter DNA sequence motifs. GO:0001071 : nucleic acid binding transcription factor activity + subset: high_level_annotation_qc GO:0001076 : RNA polymerase II transcription factor binding transcription factor activity - def: Interacting selectively and non-covalently with an RNA polymerase II transcription factor in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well. + def: Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0001082 : RNA polymerase I transcription factor binding transcription factor activity - def: Interacting selectively and non-covalently with an RNA polymerase I transcription factor in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well. + def: Interacting selectively and non-covalently with an RNA polymerase I transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0001083 : RNA polymerase II basal transcription factor binding transcription factor activity - def: Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well. + def: Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0001134 : transcription factor recruiting transcription factor activity - def: The function of binding to a transcription factor and recruiting it to the transcription machinery complex in order to modulate transcription. + def: Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, recruiting that specific transcription factor to the transcription machinery complex and thus permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0001139 : core RNA polymerase II recruiting transcription factor activity - def: Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, in order to facilitate the aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase. + def: Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way in order to facilitate the aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase. GO:0001320 : age-dependent response to reactive oxygen species involved in chronological cell aging - synonym: "age-dependent response to reactive oxidative species during chronological cell aging" EXACT [] + synonym: "age-dependent response to reactive oxidative species during chronological cell aging" RELATED [] GO:0003199 : endocardial cushion to mesenchymal transition involved in heart valve formation - name: endocardial cushion to mesenchymal transition involved in valve formation + name: endocardial cushion to mesenchymal transition involved in heart valve formation + synonym: "endocardial cushion to mesenchymal transition involved in valve formation" EXACT [GOC:bf] GO:0003249 : cell proliferation involved in heart valve morphogenesis + is_a: GO:2000793 GO:0003302 : transforming growth factor beta receptor signaling pathway involved in heart jogging + is_a: GO:0035463 GO:0003850 : 2-deoxyglucose-6-phosphatase activity + xref: KEGG:R02587 - is_a: GO:0019203 + is_a: GO:0050308 GO:0004331 : fructose-2,6-bisphosphate 2-phosphatase activity - is_a: GO:0019203 + is_a: GO:0050308 GO:0004346 : glucose-6-phosphatase activity - def: Catalysis of the reaction: D-glucose 6-phosphate + H2O = D-glucose + phosphate. + def: Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate. + xref: RHEA:16692 + xref: KEGG:R00303 - is_a: GO:0019203 + is_a: GO:0050309 GO:0006849 : plasma membrane pyruvate transport + is_a: GO:0034220 GO:0008877 : glucose-1-phosphatase activity - def: Catalysis of the reaction: D-glucose 1-phosphate + H2O = D-glucose + phosphate. + def: Catalysis of the reaction: alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate. + xref: RHEA:19936 + xref: KEGG:R00304 - is_a: GO:0019203 + is_a: GO:0050308 GO:0010569 : regulation of double-strand break repair via homologous recombination - is_a: GO:0006282 + is_a: GO:2000779 GO:0010746 : regulation of plasma membrane long-chain fatty acid transport + is_a: GO:0034762 GO:0010747 : positive regulation of plasma membrane long-chain fatty acid transport + is_a: GO:0034764 GO:0010748 : negative regulation of plasma membrane long-chain fatty acid transport + is_a: GO:0034763 GO:0014902 : myotube differentiation - is_a: GO:0051146 + is_a: GO:0035914 GO:0015911 : plasma membrane long-chain fatty acid transport + is_a: GO:0055085 GO:0019050 : suppression by virus of host apoptosis - is_a: GO:0019054 + is_a: GO:0039526 GO:0019051 : induction by virus of host apoptosis - is_a: GO:0019054 + is_a: GO:0039526 GO:0019057 : modulation by virus of host translation - name: modulation of host translation by virus + name: modulation by virus of host translation + synonym: "modulation of host translation by virus" EXACT [GOC:bf] GO:0019363 : pyridine nucleotide biosynthetic process - is_a: GO:0042364 GO:0019364 : pyridine nucleotide catabolic process - is_a: GO:0042365 GO:0019975 : interleukin-17 binding - def: Interacting selectively and non-covalently with interleukin-17. + def: Interacting selectively and non-covalently with any member of the interleukin-17 family of cytokines. GO:0030368 : interleukin-17 receptor activity - def: Combining with interleukin-17 to initiate a change in cell activity. + def: Combining with any member of the interleukin-17 family of cytokines to initiate a change in cell activity. GO:0030953 : astral microtubule organization - name: spindle astral microtubule organization + name: astral microtubule organization GO:0030954 : astral microtubule nucleation - name: spindle astral microtubule nucleation + name: astral microtubule nucleation GO:0031053 : primary miRNA processing - name: primary microRNA processing + name: primary miRNA processing - synonym: "primary miRNA processing" EXACT [] + synonym: "primary microRNA processing" EXACT [] GO:0031054 : pre-miRNA processing - name: pre-microRNA processing + name: pre-miRNA processing - synonym: "pre-miRNA processing" EXACT [] + synonym: "pre-microRNA processing" EXACT [] GO:0031623 : receptor internalization - def: A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation; receptors are subsequently taken up into endocytic vesicles and targeted to the lysosome or vacuole for degradation. Receptor internalization serves as a mechanism to downregulate receptor signaling. + def: A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane. GO:0031657 : regulation of cyclin-dependent protein kinase activity involved in G1/S - name: regulation of cyclin-dependent protein kinase activity involved by G1/S + name: regulation of cyclin-dependent protein kinase activity involved in G1/S GO:0032620 : interleukin-17 production - def: The appearance of interleukin-17 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. + def: The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. GO:0032660 : regulation of interleukin-17 production - def: Any process that modulates the frequency, rate, or extent of interleukin-17 production. + def: Any process that modulates the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines. GO:0032700 : negative regulation of interleukin-17 production - def: Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-17 production. + def: Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines. GO:0032740 : positive regulation of interleukin-17 production - def: Any process that activates or increases the frequency, rate, or extent of interleukin-17 production. + def: Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines. GO:0032932 : negative regulation of astral microtubule depolymerization - name: negative regulation of spindle astral microtubule depolymerization + name: negative regulation of astral microtubule depolymerization GO:0033209 : tumor necrosis factor-mediated signaling pathway - def: A series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor. + def: A series of molecular signals generated as a consequence of a tumor necrosis factor binding to a cell surface receptor. - synonym: "tumor necrosis factor alpha-mediated signaling pathway" EXACT [] - synonym: "TNF-alpha-mediated signaling pathway" EXACT [] + synonym: "tumor necrosis factor alpha-mediated signaling pathway" NARROW [] + synonym: "TNF-alpha-mediated signaling pathway" NARROW [] GO:0034246 : mitochondrial RNA polymerase binding promoter specificity activity - def: An activity that binds to mitochondrial RNA polymerase and which while present in a complex with the mitochondrial RNA polymerase confers sequence specific recognition of mitochondrial promoter DNA sequence motifs. + def: Interacting selectively and non-covalently with a mitochondrial RNA polymerase to form a holoenzyme complex and also, while present in the holoenzyme, interacting with promoter sequences in order to confer sequence specific recognition of mitochondrial promoter DNA sequence motifs. GO:0035195 : gene silencing by miRNA + synonym: "gene silencing by microRNA" EXACT [GOC:pr] GO:0035196 : production of miRNAs involved in gene silencing by miRNA + synonym: "production of microRNAs involved in gene silencing by microRNA" EXACT [GOC:pr] GO:0035278 : negative regulation of translation involved in gene silencing by miRNA + synonym: "negative regulation of translation involved in gene silencing by microRNA" EXACT [GOC:pr] GO:0035279 : mRNA cleavage involved in gene silencing by miRNA + synonym: "mRNA cleavage involved in gene silencing by microRNA" EXACT [GOC:pr] GO:0035280 : miRNA loading onto RISC involved in gene silencing by miRNA + synonym: "microRNA loading onto RISC involved in gene silencing by microRNA" EXACT [GOC:pr] GO:0035281 : pre-miRNA export from nucleus - name: pre-microRNA export from nucleus + name: pre-miRNA export from nucleus + synonym: "pre-microRNA export from nucleus" RELATED [] GO:0035424 : MAPK import into nucleus involved in innate immune response + is_a: GO:0035556 GO:0035893 : negative regulation of platelet aggregation in other organism + is_a: GO:0035899 GO:0039502 : suppression by virus of host type I interferon-mediated signaling pathway + is_a: GO:0019054 GO:0042132 : fructose 1,6-bisphosphate 1-phosphatase activity - is_a: GO:0019203 + is_a: GO:0050308 GO:0042235 : interleukin-17 biosynthetic process - def: The chemical reactions and pathways resulting in the formation of interleukin-17. + def: The chemical reactions and pathways resulting in the formation of any member of the interleukin-17 family of cytokines. GO:0045378 : regulation of interleukin-17 biosynthetic process - def: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-17. + def: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of any member of the interleukin-17 family of cytokines. GO:0045379 : negative regulation of interleukin-17 biosynthetic process - def: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-17. + def: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of any member of the interleukin-17 family of cytokines. GO:0045380 : positive regulation of interleukin-17 biosynthetic process - def: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-17. + def: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of any member of the interleukin-17 family of cytokines. GO:0046778 : modification by virus of host mRNA processing - is_a: GO:0019056 + is_a: GO:0019054 GO:0046780 : suppression by virus of host mRNA splicing - is_a: GO:0046778 + is_a: GO:0039524 GO:0047386 : fructose-2,6-bisphosphate 6-phosphatase activity - is_a: GO:0016791 + is_a: GO:0050308 GO:0050307 : sucrose-phosphate phosphatase activity - name: sucrose-phosphatase activity + name: sucrose-phosphate phosphatase activity - synonym: "sucrose-6F-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.24] - synonym: "sucrose-6-phosphatase activity" EXACT [EC:3.1.3.24] + synonym: "sucrose-6F-phosphate phosphohydrolase activity" EXACT systematic_synonym [EC:3.1.3.24] + xref: KEGG:R00805 + xref: KEGG:R06211 + xref: RHEA:19292 - is_a: GO:0016791 + is_a: GO:0050308 GO:0050308 : sugar-phosphatase activity - synonym: "sugar-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.23] + synonym: "sugar-phosphate phosphohydrolase activity" EXACT systematic_synonym [EC:3.1.3.23] + synonym: "sugar-phosphate phosphatase activity" EXACT [] + xref: KEGG:R00804 - is_a: GO:0016791 + is_a: GO:0019203 GO:0050309 : sugar-terminal-phosphatase activity - def: Catalysis of the reaction: H2O + a sugar phosphate = a sugar + phosphate; for example: D-glucose 6-phosphate + H2O = D-glucose + phosphate. + def: Catalysis of the reaction: H2O + sugar phosphorylated on the terminal carbon = a sugar + phosphate. - synonym: "xylitol-5-phosphatase activity" EXACT [EC:3.1.3.58] - synonym: "sugar-omega-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.58] + synonym: "xylitol-5-phosphatase activity" NARROW [EC:3.1.3.58] + synonym: "sugar-omega-phosphate phosphohydrolase activity" EXACT systematic_synonym [EC:3.1.3.58] - xref: MetaCyc:SUGAR-TERMINAL-PHOSPHATASE-RXN - is_a: GO:0019203 + is_a: GO:0050308 GO:0060172 : astral microtubule depolymerization - name: spindle astral microtubule depolymerization + name: astral microtubule depolymerization GO:0060414 : aorta smooth muscle tissue morphogenesis - def: The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. The aorta originates in the left ventricle of the heart and transports oxygenated blood to the rest of the body. + def: The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. - relationship: part_of GO:0048844 + relationship: part_of GO:0035909 GO:0060804 : positive regulation of Wnt receptor signaling pathway by BMP signaling pathway - name: positive regulation of WNT receptor signaling pathway by BMP signaling pathway + name: positive regulation of Wnt receptor signaling pathway by BMP signaling pathway - def: A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in an increase in the rate, frequency or extent of a WNT receptor signaling pathway. + def: A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in an increase in the rate, frequency or extent of a Wnt receptor signaling pathway. + synonym: "positive regulation of WNT receptor signaling pathway by BMP signaling pathway" EXACT [GOC:bf] GO:0060948 : cardiac vascular smooth muscle cell development + is_a: GO:0097084 GO:0060949 : cardiac vascular smooth muscle cell fate commitment + is_a: GO:0097081 GO:0060964 : regulation of gene silencing by miRNA + synonym: "regulation of gene silencing by microRNA" EXACT [GOC:pr] GO:0060965 : negative regulation of gene silencing by miRNA + synonym: "negative regulation of gene silencing by miRNA" EXACT [GOC:pr] GO:0061050 : regulation of cell growth involved in cardiac muscle cell development + is_a: GO:2000725 GO:0061246 : establishment or maintenance of bipolar cell polarity regulating cell shape - is_a: GO:0008360 + is_a: GO:0071963 GO:0061340 : establishment or maintenance of monopolar cell polarity regulating in cell shape - is_a: GO:0008360 + is_a: GO:0071963 GO:0061362 : negative regulation of maintenance of bipolar cell polarity regulating cell shape + is_a: GO:2000750 GO:0061372 : activin receptor signaling pathway involved in heart jogging + is_a: GO:0061311 GO:0070456 : galactose-1-phosphate phosphatase activity - is_a: GO:0016791 + is_a: GO:0050308 GO:0070878 : primary miRNA binding - name: pri-miRNA binding + name: primary miRNA binding + synonym: "pri-miRNA binding" EXACT [] GO:0070883 : pre-miRNA binding + synonym: "pre-microRNA binding" EXACT [GOC:pr] GO:0071430 : pre-miRNA-containing ribonucleoprotein complex export from nucleus - name: pre-microRNA-containing ribonucleoprotein complex export from nucleus + name: pre-miRNA-containing ribonucleoprotein complex export from nucleus + synonym: "pre-microRNA-containing ribonucleoprotein complex export from nucleus" EXACT [] GO:0071527 : semaphorin-plexin signaling pathway involved in outflow tract morphogenesis + is_a: GO:0061311 GO:0071847 : TNFSF11-mediated signaling pathway + synonym: "tumor necrosis factor superfamily member 11-mediated signaling pathway" EXACT [Wikipedia:RANKL] + synonym: "receptor activator of nuclear factor kappa-B ligand signaling pathway" EXACT [Wikipedia:RANKL] + synonym: "TNF-related activation-induced cytokine-mediated signaling pathway" EXACT [Wikipedia:RANKL] - is_a: GO:0019221 + is_a: GO:0033209 GO:0072615 : interleukin-17 secretion - def: The regulated release of interleukin-17 from a cell or group of cells. + def: The regulated release of any member of the interleukin-17 family of cytokines from a cell or group of cells. GO:0090342 : regulation of cell aging - synonym: "regulation of cellular senescence" EXACT [GOC:BHF, GOC:dph, GOC:tb] + intersection_of: GO:0065007 + intersection_of: regulates GO:0007569 GO:0090343 : positive regulation of cell aging - synonym: "positive regulation of cellular senescence" EXACT [GOC:BHF, GOC:dph, GOC:tb] GO:0090344 : negative regulation of cell aging - synonym: "negative regulation of cellular senescence" EXACT [GOC:BHF, GOC:dph, GOC:tb] GO:0097068 : response to thyroxine stimulus + synonym: "response to T4 stimulus" EXACT [Wikipedia:Thyroxine] + synonym: "response to T4" EXACT [Wikipedia:Thyroxine] GO:0097069 : cellular response to thyroxine stimulus + synonym: "cellular response to T4 stimulus" EXACT [Wikipedia:Thyroxine] GO:0097073 : interferon regulatory factor 5 complex GO:0097080 : plasma membrane selenite transport + synonym: "plasma membrane hydrogenselenite transport" EXACT [] GO:2000036 : regulation of stem cell maintenance + is_a: GO:2000736 GO:2000042 : negative regulation of double-strand break repair via homologous recombination - is_a: GO:0045738 + is_a: GO:2000780 GO:2000100 : regulation of establishment or maintenance of bipolar cell polarity regulating cell shape + is_a: GO:2000769 GO:2000247 : positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape - is_a: GO:0048522 + is_a: GO:2000771 GO:2000477 : regulation of metanephric glomerular visceral epithelial cell development + is_a: GO:2000696 GO:2000631 : regulation of pre-miRNA processing - name: regulation of pre-microRNA processing + name: regulation of pre-miRNA processing + synonym: "regulation of pre-microRNA processing" EXACT [] GO:2000632 : negative regulation of pre-miRNA processing - name: negative regulation of pre-microRNA processing + name: negative regulation of pre-miRNA processing - synonym: "negative regulation of pre-miRNA processing" EXACT [GOC:obol] + synonym: "negative regulation of pre-microRNA processing" EXACT [GOC:obol] GO:2000633 : positive regulation of pre-miRNA processing - name: positive regulation of pre-microRNA processing + name: positive regulation of pre-miRNA processing - synonym: "positive regulation of pre-miRNA processing" EXACT [GOC:obol] + synonym: "positive regulation of pre-microRNA processing" EXACT [GOC:obol] GO:2000634 : regulation of primary miRNA processing - name: regulation of primary microRNA processing + name: regulation of primary miRNA processing - synonym: "regulation of primary miRNA processing" EXACT [GOC:obol] + synonym: "regulation of primary microRNA processing" EXACT [GOC:obol] GO:2000635 : negative regulation of primary miRNA processing - name: negative regulation of primary microRNA processing + name: negative regulation of primary miRNA processing - synonym: "negative regulation of primary miRNA processing" EXACT [GOC:obol] + synonym: "negative regulation of primary microRNA processing" EXACT [GOC:obol] GO:2000636 : positive regulation of primary miRNA processing - name: positive regulation of primary microRNA processing + name: positive regulation of primary miRNA processing - synonym: "positive regulation of primary miRNA processing" EXACT [GOC:obol] + synonym: "positive regulation of primary microRNA processing" EXACT [GOC:obol] GO:2000637 : positive regulation of gene silencing by miRNA + synonym: "positive regulation of gene silencing by microRNA" RELATED [GOC:pr] GO:2000722 : regulation of cardiac vascular smooth muscle cell differentiation + is_a: GO:2000026 GO:2000725 : regulation of cardiac muscle cell differentiation + is_a: GO:0055024 GO:2000730 : regulation of termination of RNA polymerase I transcription + is_a: GO:0006356 GO:2000733 : regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation + is_a: GO:0072106 GO:2000750 : negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape - is_a: GO:0048523 + is_a: GO:2000770 FILE STATS ========== Term counts for the old and new files Ontology Old file New file Change molecular function 9023 9023 (9023 defined) (9023 defined) cellular component 2854 2855 +1 (2854 defined) (2855 defined) biological process 20896 20983 +87 (20896 defined) (20982 defined) Obsolete 1559 1559 0 (4.5% of total) (4.5% of total) (0.0%) Totals 32773 32861 +88 (+0.3%) 32773 (100.0%) defined 32860 (100.0%) defined 34332 inc. obs 34420 inc. obs