Ontology Comparison Report

Files used:

file 1 (old): go-2011-06-18.obo; date: 17:06:2011 13:42; CVS revision: 1.2042
file 2 (new): go-2011-06-25.obo; date: 24:06:2011 15:09; CVS revision: 1.2067

New terms
Obsoletions
Term merges
Term changes
File Stats

New terms

ID	name	namespace
GO:0001173	DNA-dependent transcriptional start site selection	biological_process
GO:0001174	transcriptional start site selection at RNA polymerase II promoter	biological_process
GO:0001175	transcriptional start site selection at RNA polymerase III promoter	biological_process
GO:0001176	transcriptional start site selection at bacterial-type RNA polymerase promoter	biological_process
GO:0001177	regulation of transcriptional open complex formation at RNA polymerase II promoter	biological_process
GO:0001178	regulation of transcriptional start site selection at RNA polymerase II promoter	biological_process
GO:0002188	translation reinitiation	biological_process
GO:0035898	parathyroid hormone secretion	biological_process
GO:0035899	negative regulation of blood coagulation in other organism	biological_process
GO:0035900	response to isolation stress	biological_process
GO:0035901	cellular response to isolation stress	biological_process
GO:0035902	response to immobilization stress	biological_process
GO:0035903	cellular response to immobilization stress	biological_process
GO:0035904	aorta development	biological_process
GO:0035905	ascending aorta development	biological_process
GO:0035906	descending aorta development	biological_process
GO:0035907	dorsal aorta development	biological_process
GO:0035908	ventral aorta development	biological_process
GO:0035909	aorta morphogenesis	biological_process
GO:0035910	ascending aorta morphogenesis	biological_process
GO:0035911	descending aorta morphogenesis	biological_process
GO:0035912	dorsal aorta morphogenesis	biological_process
GO:0035913	ventral aorta morphogenesis	biological_process
GO:0035914	skeletal muscle cell differentiation	biological_process
GO:0038008	TRAF-mediated signal transduction	biological_process
GO:0038009	regulation of signal transduction by receptor internalization	biological_process
GO:0038010	positive regulation of signal transduction by receptor internalization	biological_process
GO:0038011	negative regulation of signal transduction by receptor internalization	biological_process
GO:0038012	negative regulation of Wnt receptor signaling pathway by Wnt receptor internalization	biological_process
GO:0038013	positive regulation of Wnt receptor signaling pathway by Wnt receptor internalization	biological_process
GO:0038014	negative regulation of insulin receptor signaling pathway by insulin receptor internalization	biological_process
GO:0038015	positive regulation of insulin receptor signaling pathway by insulin receptor internalization	biological_process
GO:0038016	insulin receptor internalization	biological_process
GO:0038017	Wnt receptor internalization	biological_process
GO:0038018	Wnt receptor catabolic process	biological_process
GO:0038019	Wnt receptor recycling	biological_process
GO:0038020	insulin receptor recycling	biological_process
GO:0039518	suppression by virus of host cytokine activity	biological_process
GO:0039519	modulation by virus of host autophagy	biological_process
GO:0039520	induction by virus of host autophagy	biological_process
GO:0039521	suppression by virus of host autophagy	biological_process
GO:0039522	suppression by virus of host mRNA export from nucleus	biological_process
GO:0039523	suppression by virus of host RNA polymerase II activity	biological_process
GO:0039524	suppression by virus of host mRNA processing	biological_process
GO:0039525	modulation by virus of host chromatin organization	biological_process
GO:0039526	modulation by virus of host apoptosis	biological_process
GO:0039527	suppression by virus of host TRAF-mediated signal transduction	biological_process
GO:0071963	establishment or maintenance of cell polarity regulating cell shape	biological_process
GO:0071964	establishment of cell polarity regulating cell shape	biological_process
GO:0097081	vascular smooth muscle cell fate commitment	biological_process
GO:0097082	vascular smooth muscle cell fate specification	biological_process
GO:0097083	vascular smooth muscle cell fate determination	biological_process
GO:0097084	vascular smooth muscle cell development	biological_process
GO:0097085	interferon regulatory factor 3-interferon regulatory factor 5 complex	cellular_component
GO:0097086	amniotic stem cell differentiation	biological_process
GO:0097087	interleukin-17A production	biological_process
GO:0097088	interleukin-17F production	biological_process
GO:2000763	positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process	biological_process
GO:2000764	positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis	biological_process
GO:2000765	regulation of cytoplasmic translation	biological_process
GO:2000766	negative regulation of cytoplasmic translation	biological_process
GO:2000767	positive regulation of cytoplasmic translation	biological_process
GO:2000768	positive regulation of nephron tubule epithelial cell differentiation	biological_process
GO:2000769	regulation of establishment or maintenance of cell polarity regulating cell shape	biological_process
GO:2000770	negative regulation of establishment or maintenance of cell polarity regulating cell shape	biological_process
GO:2000771	positive regulation of establishment or maintenance of cell polarity regulating cell shape	biological_process
GO:2000772	regulation of cellular senescence	biological_process
GO:2000773	negative regulation of cellular senescence	biological_process
GO:2000774	positive regulation of cellular senescence	biological_process
GO:2000775	histone H3-S10 phosphorylation involved in chromosome condensation	biological_process
GO:2000776	histone H4 acetylation involved in response to DNA damage stimulus	biological_process
GO:2000777	positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia	biological_process
GO:2000778	positive regulation of interleukin-6 secretion	biological_process
GO:2000779	regulation of double-strand break repair	biological_process
GO:2000780	negative regulation of double-strand break repair	biological_process
GO:2000781	positive regulation of double-strand break repair	biological_process
GO:2000782	regulation of establishment of cell polarity regulating cell shape	biological_process
GO:2000783	negative regulation of establishment of cell polarity regulating cell shape	biological_process
GO:2000784	positive regulation of establishment of cell polarity regulating cell shape	biological_process
GO:2000785	regulation of autophagic vacuole assembly	biological_process
GO:2000786	positive regulation of autophagic vacuole assembly	biological_process
GO:2000787	regulation of venous endothelial cell fate commitment	biological_process
GO:2000788	negative regulation of venous endothelial cell fate commitment	biological_process
GO:2000789	positive regulation of venous endothelial cell fate commitment	biological_process
GO:2000790	regulation of mesenchymal cell proliferation involved in lung development	biological_process
GO:2000791	negative regulation of mesenchymal cell proliferation involved in lung development	biological_process
GO:2000792	positive regulation of mesenchymal cell proliferation involved in lung development	biological_process
GO:2000793	cell proliferation involved in heart valve development	biological_process

Obsoletions

None

Term merges

None

Term changes

Changes in term-related data
File 1 (17:06:2011 13:42, 1.2042)	File 2 (24:06:2011 15:09, 1.2067)

GO:0000408 : EKC/KEOPS complex
name ~~EKC/KEOPS protein complex~~	name EKC/KEOPS complex

GO:0000988 : protein binding transcription factor activity
	subset high_level_annotation_qc

GO:0000989 : transcription factor binding transcription factor activity
def Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.	def Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0000989 : transcription factor binding transcription factor activity

def
Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.

def
Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0000990 : core RNA polymerase binding transcription factor activity
def ~~Interacting selectively and non-covalently with an RNA polymerase in order to modulate transcription.~~	def Interacting selectively and non-covalently with an RNA polymerase and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0000991 : core RNA polymerase II binding transcription factor activity
def ~~Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, in order to modulate transcription by Pol II.~~	def Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0000991 : core RNA polymerase II binding transcription factor activity

def
~~Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, in order to modulate transcription by Pol II.~~

def
Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0000995 : core RNA polymerase III binding transcription factor activity
def ~~Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, in order to modulate transcription by Pol III.~~	def Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0000996 : core DNA-dependent RNA polymerase binding promoter specificity activity
name ~~core RNA polymerase binding promoter specificity activity~~ def ~~An activity that binds to RNA polymerase and which while present in a complex with the core RNA polymerase confers sequence specific recognition of promoter DNA sequence motifs.~~	name core DNA-dependent RNA polymerase binding promoter specificity activity def Interacting selectively and non-covalently with a DNA-dependent core RNA polymerase to form a holoenzyme complex and also, while present in the holoenzyme, interacting with promoter sequences in order to confer sequence specific recognition of promoter DNA sequence motifs.

GO:0001007 : RNA polymerase III transcription factor binding transcription factor activity
def Interacting selectively and non-covalently with an RNA polymerase III transcription factor in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.	def Interacting selectively and non-covalently with an RNA polymerase III transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0001007 : RNA polymerase III transcription factor binding transcription factor activity

def
Interacting selectively and non-covalently with an RNA polymerase III transcription factor in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.

def
Interacting selectively and non-covalently with an RNA polymerase III transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0001026 : TFIIIB-type transcription factor activity
def Once recruited to an RNA polymerase III promoter by one or more other transcription factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.	def Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, Once recruited to an RNA polymerase III promoter by one or more other transcription factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.

GO:0001026 : TFIIIB-type transcription factor activity

def
Once recruited to an RNA polymerase III promoter by one or more other transcription factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.

def
Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, Once recruited to an RNA polymerase III promoter by one or more other transcription factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.

GO:0001027 : RNA polymerase III type 1 promoter TFIIIB-type transcription factor activity
def Once recruited to an RNA polymerase III type 1 promoter by TFIIIA-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.	def Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 1 promoter by TFIIIA-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.

GO:0001027 : RNA polymerase III type 1 promoter TFIIIB-type transcription factor activity

def
Once recruited to an RNA polymerase III type 1 promoter by TFIIIA-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.

def
Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 1 promoter by TFIIIA-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.

GO:0001028 : RNA polymerase III type 2 promoter TFIIIB-type transcription factor activity
def ~~Once recruited to an RNA polymerase III type 2 promoter by a TFIIIC-type factor, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.~~	def Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 2 promoter by a TFIIIC-type factor, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.

GO:0001028 : RNA polymerase III type 2 promoter TFIIIB-type transcription factor activity

def
~~Once recruited to an RNA polymerase III type 2 promoter by a TFIIIC-type factor, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.~~

def
Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 2 promoter by a TFIIIC-type factor, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.

GO:0001029 : RNA polymerase III type 3 promoter TFIIIB-type transcription factor activity
def Once recruited to an RNA polymerase III type 3 promoter by SNAP-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.	def Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 3 promoter by SNAP-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.

GO:0001029 : RNA polymerase III type 3 promoter TFIIIB-type transcription factor activity

def
Once recruited to an RNA polymerase III type 3 promoter by SNAP-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.

def
Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 3 promoter by SNAP-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.

GO:0001040 : RNA polymerase III hybrid type promoter TFIIIB-type transcription factor activity
def ~~Once recruited to an RNA polymerase III hybrid type promoter, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.~~	def Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III hybrid type promoter, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.

GO:0001040 : RNA polymerase III hybrid type promoter TFIIIB-type transcription factor activity

def
~~Once recruited to an RNA polymerase III hybrid type promoter, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.~~

def
Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III hybrid type promoter, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.

GO:0001053 : plastid sigma factor activity
def ~~A sigma factor that binds to the plastid PEP core RNA polymerase enzyme to confer promoter specificity.~~	def Interacting selectively and non-covalently with a plastid PEP core RNA polymerase to form a holoenzyme complex and also, while present in the holoenzyme, interacting with promoter sequences in order to confer sequence specific recognition of plastid PEP core promoter DNA sequence motifs.

GO:0001071 : nucleic acid binding transcription factor activity
	subset high_level_annotation_qc

GO:0001076 : RNA polymerase II transcription factor binding transcription factor activity
def Interacting selectively and non-covalently with an RNA polymerase II transcription factor in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.	def Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0001076 : RNA polymerase II transcription factor binding transcription factor activity

def
Interacting selectively and non-covalently with an RNA polymerase II transcription factor in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.

def
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0001082 : RNA polymerase I transcription factor binding transcription factor activity
def Interacting selectively and non-covalently with an RNA polymerase I transcription factor in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.	def Interacting selectively and non-covalently with an RNA polymerase I transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0001082 : RNA polymerase I transcription factor binding transcription factor activity

def
Interacting selectively and non-covalently with an RNA polymerase I transcription factor in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.

def
Interacting selectively and non-covalently with an RNA polymerase I transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0001083 : RNA polymerase II basal transcription factor binding transcription factor activity
def Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.	def Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0001083 : RNA polymerase II basal transcription factor binding transcription factor activity

def
Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.

def
Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0001134 : transcription factor recruiting transcription factor activity
def ~~The function of binding to a transcription factor and recruiting it to the transcription machinery complex in order to modulate transcription.~~	def Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, recruiting that specific transcription factor to the transcription machinery complex and thus permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0001134 : transcription factor recruiting transcription factor activity

def
~~The function of binding to a transcription factor and recruiting it to the transcription machinery complex in order to modulate transcription.~~

def
Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, recruiting that specific transcription factor to the transcription machinery complex and thus permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0001139 : core RNA polymerase II recruiting transcription factor activity
def Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, in order to facilitate the aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.	def Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way in order to facilitate the aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.

GO:0001139 : core RNA polymerase II recruiting transcription factor activity

def
Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, in order to facilitate the aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.

def
Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way in order to facilitate the aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.

GO:0001320 : age-dependent response to reactive oxygen species involved in chronological cell aging
synonym ~~"age-dependent response to reactive oxidative species during chronological cell aging" EXACT []~~	synonym "age-dependent response to reactive oxidative species during chronological cell aging" RELATED []

GO:0003199 : endocardial cushion to mesenchymal transition involved in heart valve formation
name ~~endocardial cushion to mesenchymal transition involved in valve formation~~	name endocardial cushion to mesenchymal transition involved in heart valve formation synonym "endocardial cushion to mesenchymal transition involved in valve formation" EXACT [GOC:bf]

GO:0003249 : cell proliferation involved in heart valve morphogenesis
	is_a GO:2000793

GO:0003302 : transforming growth factor beta receptor signaling pathway involved in heart jogging
	is_a GO:0035463

GO:0003850 : 2-deoxyglucose-6-phosphatase activity
is_a ~~GO:0019203~~	xref KEGG:R02587 is_a GO:0050308

GO:0004331 : fructose-2,6-bisphosphate 2-phosphatase activity
is_a ~~GO:0019203~~	is_a GO:0050308

GO:0004346 : glucose-6-phosphatase activity
def ~~Catalysis of the reaction: D-glucose 6-phosphate + H2O = D-glucose + phosphate.~~ is_a ~~GO:0019203~~	def Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate. xref KEGG:R00303 RHEA:16692 is_a GO:0050309

GO:0006849 : plasma membrane pyruvate transport
	is_a GO:0034220

GO:0008877 : glucose-1-phosphatase activity
def ~~Catalysis of the reaction: D-glucose 1-phosphate + H2O = D-glucose + phosphate.~~ is_a ~~GO:0019203~~	def Catalysis of the reaction: alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate. xref KEGG:R00304 RHEA:19936 is_a GO:0050308

GO:0010569 : regulation of double-strand break repair via homologous recombination
is_a ~~GO:0006282~~	is_a GO:2000779

GO:0010746 : regulation of plasma membrane long-chain fatty acid transport
	is_a GO:0034762

GO:0010747 : positive regulation of plasma membrane long-chain fatty acid transport
	is_a GO:0034764

GO:0010748 : negative regulation of plasma membrane long-chain fatty acid transport
	is_a GO:0034763

GO:0014902 : myotube differentiation
is_a ~~GO:0051146~~	is_a GO:0035914

GO:0015911 : plasma membrane long-chain fatty acid transport
	is_a GO:0055085

GO:0019050 : suppression by virus of host apoptosis
is_a ~~GO:0019054~~	is_a GO:0039526

GO:0019051 : induction by virus of host apoptosis
is_a ~~GO:0019054~~	is_a GO:0039526

GO:0019057 : modulation by virus of host translation
name ~~modulation of host translation by virus~~	name modulation by virus of host translation synonym "modulation of host translation by virus" EXACT [GOC:bf]

GO:0019363 : pyridine nucleotide biosynthetic process
is_a ~~GO:0042364~~

GO:0019364 : pyridine nucleotide catabolic process
is_a ~~GO:0042365~~

GO:0019975 : interleukin-17 binding
def ~~Interacting selectively and non-covalently with interleukin-17.~~	def Interacting selectively and non-covalently with any member of the interleukin-17 family of cytokines.

GO:0030368 : interleukin-17 receptor activity
def ~~Combining with interleukin-17 to initiate a change in cell activity.~~	def Combining with any member of the interleukin-17 family of cytokines to initiate a change in cell activity.

GO:0030953 : astral microtubule organization
name ~~spindle astral microtubule organization~~	name astral microtubule organization

GO:0030954 : astral microtubule nucleation
name ~~spindle astral microtubule nucleation~~	name astral microtubule nucleation

GO:0031053 : primary miRNA processing
name ~~primary microRNA processing~~ synonym ~~"primary miRNA processing" EXACT []~~	name primary miRNA processing synonym "primary microRNA processing" EXACT []

GO:0031054 : pre-miRNA processing
name ~~pre-microRNA processing~~ synonym ~~"pre-miRNA processing" EXACT []~~	name pre-miRNA processing synonym "pre-microRNA processing" EXACT []

GO:0031623 : receptor internalization
def A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation; receptors are subsequently taken up into endocytic vesicles and targeted to the lysosome or vacuole for degradation. Receptor internalization serves as a mechanism to downregulate receptor signaling.	def A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane.

GO:0031623 : receptor internalization

def
A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation; receptors are subsequently taken up into endocytic vesicles and targeted to the lysosome or vacuole for degradation. Receptor internalization serves as a mechanism to downregulate receptor signaling.

def
A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane.

GO:0031657 : regulation of cyclin-dependent protein kinase activity involved in G1/S
name ~~regulation of cyclin-dependent protein kinase activity involved by G1/S~~	name regulation of cyclin-dependent protein kinase activity involved in G1/S

GO:0032620 : interleukin-17 production
def ~~The appearance of interleukin-17 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.~~	def The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.

GO:0032660 : regulation of interleukin-17 production
def ~~Any process that modulates the frequency, rate, or extent of interleukin-17 production.~~	def Any process that modulates the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.

GO:0032700 : negative regulation of interleukin-17 production
def ~~Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-17 production.~~	def Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.

GO:0032740 : positive regulation of interleukin-17 production
def ~~Any process that activates or increases the frequency, rate, or extent of interleukin-17 production.~~	def Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.

GO:0032932 : negative regulation of astral microtubule depolymerization
name ~~negative regulation of spindle astral microtubule depolymerization~~	name negative regulation of astral microtubule depolymerization

GO:0033209 : tumor necrosis factor-mediated signaling pathway
def ~~A series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.~~ synonym ~~"TNF-alpha-mediated signaling pathway" EXACT []~~ ~~"tumor necrosis factor alpha-mediated signaling pathway" EXACT []~~	def A series of molecular signals generated as a consequence of a tumor necrosis factor binding to a cell surface receptor. synonym "TNF-alpha-mediated signaling pathway" NARROW [] "tumor necrosis factor alpha-mediated signaling pathway" NARROW []

GO:0034246 : mitochondrial RNA polymerase binding promoter specificity activity
def An activity that binds to mitochondrial RNA polymerase and which while present in a complex with the mitochondrial RNA polymerase confers sequence specific recognition of mitochondrial promoter DNA sequence motifs.	def Interacting selectively and non-covalently with a mitochondrial RNA polymerase to form a holoenzyme complex and also, while present in the holoenzyme, interacting with promoter sequences in order to confer sequence specific recognition of mitochondrial promoter DNA sequence motifs.

GO:0035195 : gene silencing by miRNA
	synonym "gene silencing by microRNA" EXACT [GOC:pr]

GO:0035196 : production of miRNAs involved in gene silencing by miRNA
	synonym "production of microRNAs involved in gene silencing by microRNA" EXACT [GOC:pr]

GO:0035278 : negative regulation of translation involved in gene silencing by miRNA
	synonym "negative regulation of translation involved in gene silencing by microRNA" EXACT [GOC:pr]

GO:0035279 : mRNA cleavage involved in gene silencing by miRNA
	synonym "mRNA cleavage involved in gene silencing by microRNA" EXACT [GOC:pr]

GO:0035280 : miRNA loading onto RISC involved in gene silencing by miRNA
	synonym "microRNA loading onto RISC involved in gene silencing by microRNA" EXACT [GOC:pr]

GO:0035281 : pre-miRNA export from nucleus
name ~~pre-microRNA export from nucleus~~	name pre-miRNA export from nucleus synonym "pre-microRNA export from nucleus" RELATED []

GO:0035424 : MAPK import into nucleus involved in innate immune response
	is_a GO:0035556

GO:0035893 : negative regulation of platelet aggregation in other organism
	is_a GO:0035899

GO:0039502 : suppression by virus of host type I interferon-mediated signaling pathway
	is_a GO:0019054

GO:0042132 : fructose 1,6-bisphosphate 1-phosphatase activity
is_a ~~GO:0019203~~	is_a GO:0050308

GO:0042235 : interleukin-17 biosynthetic process
def ~~The chemical reactions and pathways resulting in the formation of interleukin-17.~~	def The chemical reactions and pathways resulting in the formation of any member of the interleukin-17 family of cytokines.

GO:0045378 : regulation of interleukin-17 biosynthetic process
def ~~Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-17.~~	def Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of any member of the interleukin-17 family of cytokines.

GO:0045379 : negative regulation of interleukin-17 biosynthetic process
def ~~Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-17.~~	def Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of any member of the interleukin-17 family of cytokines.

GO:0045380 : positive regulation of interleukin-17 biosynthetic process
def ~~Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-17.~~	def Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of any member of the interleukin-17 family of cytokines.

GO:0046778 : modification by virus of host mRNA processing
is_a ~~GO:0019056~~	is_a GO:0019054

GO:0046780 : suppression by virus of host mRNA splicing
is_a ~~GO:0046778~~	is_a GO:0039524

GO:0047386 : fructose-2,6-bisphosphate 6-phosphatase activity
is_a ~~GO:0016791~~	is_a GO:0050308

GO:0050307 : sucrose-phosphate phosphatase activity
name ~~sucrose-phosphatase activity~~ synonym ~~"sucrose-6-phosphatase activity" EXACT [EC:3.1.3.24]~~ ~~"sucrose-6F-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.24]~~ is_a ~~GO:0016791~~	name sucrose-phosphate phosphatase activity synonym "sucrose-6F-phosphate phosphohydrolase activity" EXACT systematic_synonym [EC:3.1.3.24] xref KEGG:R00805 KEGG:R06211 RHEA:19292 is_a GO:0050308

GO:0050308 : sugar-phosphatase activity
synonym ~~"sugar-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.23]~~ is_a ~~GO:0016791~~	synonym "sugar-phosphate phosphatase activity" EXACT [] "sugar-phosphate phosphohydrolase activity" EXACT systematic_synonym [EC:3.1.3.23] xref KEGG:R00804 is_a GO:0019203

GO:0050309 : sugar-terminal-phosphatase activity
def ~~Catalysis of the reaction: H2O + a sugar phosphate = a sugar + phosphate; for example: D-glucose 6-phosphate + H2O = D-glucose + phosphate.~~ synonym ~~"sugar-omega-phosphate phosphohydrolase activity" EXACT [EC:3.1.3.58]~~ ~~"xylitol-5-phosphatase activity" EXACT [EC:3.1.3.58]~~ xref ~~MetaCyc:SUGAR-TERMINAL-PHOSPHATASE-RXN~~ is_a ~~GO:0019203~~	def Catalysis of the reaction: H2O + sugar phosphorylated on the terminal carbon = a sugar + phosphate. synonym "sugar-omega-phosphate phosphohydrolase activity" EXACT systematic_synonym [EC:3.1.3.58] "xylitol-5-phosphatase activity" NARROW [EC:3.1.3.58] is_a GO:0050308

GO:0060172 : astral microtubule depolymerization
name ~~spindle astral microtubule depolymerization~~	name astral microtubule depolymerization

GO:0060414 : aorta smooth muscle tissue morphogenesis
def The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. The aorta originates in the left ventricle of the heart and transports oxygenated blood to the rest of the body. relationship ~~part_of GO:0048844~~	def The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. relationship part_of GO:0035909

GO:0060804 : positive regulation of Wnt receptor signaling pathway by BMP signaling pathway

name
~~positive regulation of WNT receptor signaling pathway by BMP signaling pathway~~
def
A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in an increase in the rate, frequency or extent of a WNT receptor signaling pathway.

name
positive regulation of Wnt receptor signaling pathway by BMP signaling pathway
def
A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in an increase in the rate, frequency or extent of a Wnt receptor signaling pathway.
synonym
"positive regulation of WNT receptor signaling pathway by BMP signaling pathway" EXACT [GOC:bf]

GO:0060948 : cardiac vascular smooth muscle cell development
	is_a GO:0097084

GO:0060949 : cardiac vascular smooth muscle cell fate commitment
	is_a GO:0097081

GO:0060964 : regulation of gene silencing by miRNA
	synonym "regulation of gene silencing by microRNA" EXACT [GOC:pr]

GO:0060965 : negative regulation of gene silencing by miRNA
	synonym "negative regulation of gene silencing by miRNA" EXACT [GOC:pr]

GO:0061050 : regulation of cell growth involved in cardiac muscle cell development
	is_a GO:2000725

GO:0061246 : establishment or maintenance of bipolar cell polarity regulating cell shape
is_a ~~GO:0008360~~	is_a GO:0071963

GO:0061340 : establishment or maintenance of monopolar cell polarity regulating in cell shape
is_a ~~GO:0008360~~	is_a GO:0071963

GO:0061362 : negative regulation of maintenance of bipolar cell polarity regulating cell shape
	is_a GO:2000750

GO:0061372 : activin receptor signaling pathway involved in heart jogging
	is_a GO:0061311

GO:0070456 : galactose-1-phosphate phosphatase activity
is_a ~~GO:0016791~~	is_a GO:0050308

GO:0070878 : primary miRNA binding
name ~~pri-miRNA binding~~	name primary miRNA binding synonym "pri-miRNA binding" EXACT []

GO:0070883 : pre-miRNA binding
	synonym "pre-microRNA binding" EXACT [GOC:pr]

GO:0071430 : pre-miRNA-containing ribonucleoprotein complex export from nucleus
name ~~pre-microRNA-containing ribonucleoprotein complex export from nucleus~~	name pre-miRNA-containing ribonucleoprotein complex export from nucleus synonym "pre-microRNA-containing ribonucleoprotein complex export from nucleus" EXACT []

GO:0071527 : semaphorin-plexin signaling pathway involved in outflow tract morphogenesis
	is_a GO:0061311

GO:0071847 : TNFSF11-mediated signaling pathway
is_a ~~GO:0019221~~	synonym "receptor activator of nuclear factor kappa-B ligand signaling pathway" EXACT [Wikipedia:RANKL] "TNF-related activation-induced cytokine-mediated signaling pathway" EXACT [Wikipedia:RANKL] "tumor necrosis factor superfamily member 11-mediated signaling pathway" EXACT [Wikipedia:RANKL] is_a GO:0033209

GO:0072615 : interleukin-17 secretion
def ~~The regulated release of interleukin-17 from a cell or group of cells.~~	def The regulated release of any member of the interleukin-17 family of cytokines from a cell or group of cells.

GO:0090342 : regulation of cell aging
synonym ~~"regulation of cellular senescence" EXACT [GOC:BHF, GOC:dph, GOC:tb]~~	intersection_of GO:0065007 regulates GO:0007569

GO:0090343 : positive regulation of cell aging
synonym ~~"positive regulation of cellular senescence" EXACT [GOC:BHF, GOC:dph, GOC:tb]~~

GO:0090344 : negative regulation of cell aging
synonym ~~"negative regulation of cellular senescence" EXACT [GOC:BHF, GOC:dph, GOC:tb]~~

GO:0097068 : response to thyroxine stimulus
	synonym "response to T4 stimulus" EXACT [Wikipedia:Thyroxine] "response to T4" EXACT [Wikipedia:Thyroxine]

GO:0097069 : cellular response to thyroxine stimulus
	synonym "cellular response to T4 stimulus" EXACT [Wikipedia:Thyroxine]

GO:0097073 : interferon regulatory factor 5 complex

GO:0097080 : plasma membrane selenite transport
	synonym "plasma membrane hydrogenselenite transport" EXACT []

GO:2000036 : regulation of stem cell maintenance
	is_a GO:2000736

GO:2000042 : negative regulation of double-strand break repair via homologous recombination
is_a ~~GO:0045738~~	is_a GO:2000780

GO:2000100 : regulation of establishment or maintenance of bipolar cell polarity regulating cell shape
	is_a GO:2000769

GO:2000247 : positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape
is_a ~~GO:0048522~~	is_a GO:2000771

GO:2000477 : regulation of metanephric glomerular visceral epithelial cell development
	is_a GO:2000696

GO:2000631 : regulation of pre-miRNA processing
name ~~regulation of pre-microRNA processing~~	name regulation of pre-miRNA processing synonym "regulation of pre-microRNA processing" EXACT []

GO:2000632 : negative regulation of pre-miRNA processing
name ~~negative regulation of pre-microRNA processing~~ synonym ~~"negative regulation of pre-miRNA processing" EXACT [GOC:obol]~~	name negative regulation of pre-miRNA processing synonym "negative regulation of pre-microRNA processing" EXACT [GOC:obol]

GO:2000633 : positive regulation of pre-miRNA processing
name ~~positive regulation of pre-microRNA processing~~ synonym ~~"positive regulation of pre-miRNA processing" EXACT [GOC:obol]~~	name positive regulation of pre-miRNA processing synonym "positive regulation of pre-microRNA processing" EXACT [GOC:obol]

GO:2000634 : regulation of primary miRNA processing
name ~~regulation of primary microRNA processing~~ synonym ~~"regulation of primary miRNA processing" EXACT [GOC:obol]~~	name regulation of primary miRNA processing synonym "regulation of primary microRNA processing" EXACT [GOC:obol]

GO:2000635 : negative regulation of primary miRNA processing
name ~~negative regulation of primary microRNA processing~~ synonym ~~"negative regulation of primary miRNA processing" EXACT [GOC:obol]~~	name negative regulation of primary miRNA processing synonym "negative regulation of primary microRNA processing" EXACT [GOC:obol]

GO:2000636 : positive regulation of primary miRNA processing
name ~~positive regulation of primary microRNA processing~~ synonym ~~"positive regulation of primary miRNA processing" EXACT [GOC:obol]~~	name positive regulation of primary miRNA processing synonym "positive regulation of primary microRNA processing" EXACT [GOC:obol]

GO:2000637 : positive regulation of gene silencing by miRNA
	synonym "positive regulation of gene silencing by microRNA" RELATED [GOC:pr]

GO:2000722 : regulation of cardiac vascular smooth muscle cell differentiation
	is_a GO:2000026

GO:2000725 : regulation of cardiac muscle cell differentiation
	is_a GO:0055024

GO:2000730 : regulation of termination of RNA polymerase I transcription
	is_a GO:0006356

GO:2000733 : regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
	is_a GO:0072106

GO:2000750 : negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape
is_a ~~GO:0048523~~	is_a GO:2000770

File Stats

Term counts for the old and new files
Ontology	Old file	New file	Change
molecular function	9023 9023 (100.0%) defined	9023 9023 (100.0%) defined	0
cellular component	2854 2854 (100.0%) defined	2855 2855 (100.0%) defined	+1
biological process	20896 20896 (100.0%) defined	20983 20982 (100.0%) defined	+87
Obsolete	1559 (4.5% of total)	1559 (4.5% of total)	0 (0.0%)
Totals	32773 32773 (100.0%) defined 34332 inc. obsoletes	32861 32860 (100.0%) defined 34420 inc. obsoletes	+88 (+0.3%)