# HISTORY 29 Aug 2016: Saved by pascalegaudet using Paint 2.22 # molecular_function 20160829: Eukaryota_PTN000366978 has function protein kinase activity (GO:0004672) 20160829: Eukaryota_PTN000366978 has function protein serine/threonine kinase activity (GO:0004674) 20160829: Amoebozoa_PTN001423729 has function myosin heavy chain kinase activity (GO:0016905) 20160829: Fungi_PTN001271469 has function GTPase activity (GO:0003924) # cellular_component 20160829: Eukaryota_PTN000366978 is found in cytoplasm (GO:0005737) 20160829: Amoebozoa_PTN001423729 is found in actomyosin contractile ring (GO:0005826) 20160829: Fungi_PTN001271469 is found in cytoplasm (GO:0005737) 20160829: Fungi_PTN001271469 is found in endoplasmic reticulum (GO:0005783) # biological_process 20160829: Amoebozoa_PTN001423729 participates in myosin II filament organization (GO:0031038) 20160829: Fungi_PTN001271469 participates in endoplasmic reticulum organization (GO:0007029) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).