# HISTORY
25 Mar 2016: Updated by: TOUCHUP-v1.15
15 Mar 2016: Updated by: TOUCHUP-v1.14

# molecular_function
20141114: root_PTN000970771 has function N-acyltransferase activity (GO:0016410) 
20141114: Eukaryota_PTN000285423 has function sphingosine N-acyltransferase activity (GO:0050291) 
20141114: Caenorhabditis elegans_PTN000285611 has LOST/MODIFIED function sphingosine N-acyltransferase activity (GO:0050291) 

# cellular_component
20141114: root_PTN000970771 is found in endoplasmic reticulum (GO:0005783) 

# biological_process
20141114: root_PTN000970771 participates in lipid metabolic process (GO:0006629) 
20141114: Eukaryota_PTN000285423 participates in ceramide biosynthetic process (GO:0046513) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
Annotation of the MF based on the mutational study of PMID: 16951403
Residues required for activity are: H182, H183, L189, D210, D213, and L216 (Figure 2).

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).