# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 14 Mar 2016: Updated by: TOUCHUP-v1.12 24 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20140311: Eukaryota_PTN000058569 has function phosphatidylinositol binding (GO:0035091) # cellular_component 20140829: Eukaryota_PTN000058569 is found in extrinsic component of membrane (GO:0019898) 20140829: Eukaryota_PTN000058569 is found in endosome (GO:0005768) 20140829: Dikarya_PTN000831256 is found in pre-autophagosomal structure (GO:0000407) 20140829: Eumetazoa_PTN000831110 is found in endosome membrane (GO:0010008) 20140312: Eumetazoa_PTN000831156 is found in cytoplasmic, membrane-bounded vesicle (GO:0016023) # biological_process 20140829: Eukaryota_PTN000058569 participates in endocytosis (GO:0006897) 20140829: Eukaryota_PTN000058569 participates in vesicle organization (GO:0016050) 20140829: Dikarya_PTN000831228 participates in protein retention in Golgi apparatus (GO:0045053) 20140312: Dikarya_PTN000831228 participates in retrograde transport, endosome to Golgi (GO:0042147) 20140312: Dikarya_PTN000831045 participates in retrograde transport, endosome to Golgi (GO:0042147) 20140829: Dikarya_PTN000831256 participates in autophagy (GO:0006914) 20140829: Dikarya_PTN000831256 participates in CVT pathway (GO:0032258) 20140829: Eumetazoa_PTN000831110 participates in early endosome to Golgi transport (GO:0034498) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES Curated by Rama 2014-03-13 Reviewed Pascale and Marc 2014-08-29 # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).